LOCUS       DAVLZS010000001        76839 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLZS010000001 DAVLZS010000000
VERSION     DAVLZS010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 76839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76839
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.001"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(42..2000)
                     /gene="ftsH"
                     /locus_tag="VYO88_000001"
     CDS             complement(42..2000)
                     /gene="ftsH"
                     /locus_tag="VYO88_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1718189.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2016..2558)
                     /gene="hpt"
                     /locus_tag="VYO88_000002"
     CDS             complement(2016..2558)
                     /gene="hpt"
                     /locus_tag="VYO88_000002"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1718190.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2562..3839)
                     /gene="tilS"
                     /locus_tag="VYO88_000003"
     CDS             complement(2562..3839)
                     /gene="tilS"
                     /locus_tag="VYO88_000003"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1718191.1"
                     /translation="MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3836..5104)
                     /locus_tag="VYO88_000004"
     CDS             complement(3836..5104)
                     /locus_tag="VYO88_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1718192.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSFPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5224..5592)
                     /locus_tag="VYO88_000005"
     CDS             complement(5224..5592)
                     /locus_tag="VYO88_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1718193.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5585..5851)
                     /locus_tag="VYO88_000006"
     CDS             complement(5585..5851)
                     /locus_tag="VYO88_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1718194.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5909..9418)
                     /gene="mfd"
                     /locus_tag="VYO88_000007"
     CDS             complement(5909..9418)
                     /gene="mfd"
                     /locus_tag="VYO88_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1718195.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELVLQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9419..9988)
                     /locus_tag="VYO88_000008"
     CDS             complement(9419..9988)
                     /locus_tag="VYO88_000008"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1718196.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10059..11174)
                     /gene="ychF"
                     /locus_tag="VYO88_000009"
     CDS             complement(10059..11174)
                     /gene="ychF"
                     /locus_tag="VYO88_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1718197.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKIVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11294..12460)
                     /locus_tag="VYO88_000010"
     CDS             complement(11294..12460)
                     /locus_tag="VYO88_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1718198.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKGGSTVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLL
                     PAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIP
                     FNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALEWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKTVLMLRLY
                     KARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHA
                     SILLNAGLPYKEIQTRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS"
     gene            complement(12556..13008)
                     /locus_tag="VYO88_000011"
     CDS             complement(12556..13008)
                     /locus_tag="VYO88_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV1718199.1"
                     /translation="MDKINYFSAEEAILLHDIEVIEKIGGLHGVKDKGRVFSVFEHLQ
                     NDDYYPDFETKLTVLVFNTVQFHMFNDGNKRSSIVFGIKFLTINHLDYLIPFFIETME
                     NIVLWVAMGLIDFNFLKEIISSILYYEELTEKVKEKLVQIALAEENNK"
     gene            complement(13008..14012)
                     /locus_tag="VYO88_000012"
     CDS             complement(13008..14012)
                     /locus_tag="VYO88_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1718200.1"
                     /translation="MTDLTTSQIERQNILNNSLALQKAEEILKVPGFYFEDTFYFTNS
                     QLATFFEVDIRTIERLVEAHKTELTENGYHTLRGEKLAKFKENAFATDTNVGSKVTQL
                     SISSFRTLLNFAMLLTNSDIAKQVRNTLLDIVINVLTEKTGGHVKFINQRDKNYLSTA
                     LEEDNARKIFTNAIDKYVSGSNFKYGQLTNEIYKAIFKERASEYKKILKLNKNDNARA
                     TMYSEVLIVIASFEKGVAYEIEQKSKSSNQKLTNTDVIEIIQRLANHPMQEPHLMHAR
                     EKMASRDLSFRNAKHEKLAEYIRPISEEDFERFIGEQSKSLSEQIDEHRQVFERLRDK
                     "
     gene            complement(14161..15117)
                     /locus_tag="VYO88_000013"
     CDS             complement(14161..15117)
                     /locus_tag="VYO88_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1718201.1"
                     /translation="MAKNSPQDLENREYFSKRLNLLMEQKGVRQIDLHNALDIPKSTI
                     TGYVKGKSLPTAGNLQKIADFLNVKKSFLDLRFIDTVSTSTLKELLDNNQREKVFEMF
                     FNKIKEILSFKKDYMNMEYIRGKIAFDQGVLGRVLQSSIINPGIVEIFNGLDLSDISK
                     NNEALLLSKQREAREYAYNNVLTMITNEYITRLINVIEREQALNTSYVHSEISNLINS
                     LNNKIDSYGAVVFEVNEIIEKIGIQDRKILGYCLQRKISSVQNEINDLVHNNTNNSFC
                     VTKNKIFTEKSDIIDTIEFDYYKGIQNRLNDLAEEIREHFSD"
     gene            15443..16090
                     /locus_tag="VYO88_000014"
     CDS             15443..16090
                     /locus_tag="VYO88_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEV1718202.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIKTWEAKPKHAHSTMNNLLLKAVTDMNAKQLVKSRGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKNTPKKRVRATKKA"
     gene            16522..16974
                     /locus_tag="VYO88_000015"
     CDS             16522..16974
                     /locus_tag="VYO88_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718203.1"
                     /translation="MTETTYENLTRRINRISAEMQEIGEKNGLSRLSLLASQTKFIKE
                     ELSRLLWIELPELNDSHKIEAVSKSTTGMFFHPGIFEMDAMRQAFFKRQAMHFFENEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            16971..17171
                     /locus_tag="VYO88_000016"
     CDS             16971..17171
                     /locus_tag="VYO88_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718204.1"
                     /translation="MTLDLDNMTQAEFDKQMAEIKERNPNIFQLISDFLDRKVTPEEV
                     DEFLKMERAEQVEYIKNYQARV"
     gene            17173..17388
                     /locus_tag="VYO88_000017"
     CDS             17173..17388
                     /locus_tag="VYO88_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718205.1"
                     /translation="MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPDYGRYIQLAGVNVWGGME"
     gene            17385..17678
                     /locus_tag="VYO88_000018"
     CDS             17385..17678
                     /locus_tag="VYO88_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718206.1"
                     /translation="MSYTMNLYPDIEKIPDETYFTKEIFLATCLNNTIRIAVARGVLT
                     SQLLDKETKEVVCKTLDTIIENQKAILQGVASGQITFVNKSKGEEGLDESIRE"
     gene            17659..18000
                     /locus_tag="VYO88_000019"
     CDS             17659..18000
                     /locus_tag="VYO88_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1718207.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            17993..18268
                     /locus_tag="VYO88_000020"
     CDS             17993..18268
                     /locus_tag="VYO88_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718208.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEAREKVPPRLTKLINRVELK
                     EELKISDNTLNKWESQGLRRYQPPDDGTRIIFYLVDDIRRFMGVENG"
     gene            18408..19268
                     /locus_tag="VYO88_000021"
     CDS             18408..19268
                     /locus_tag="VYO88_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEV1718209.1"
                     /translation="MTIYEARGFQSNLVYPFDKMEPFQYIERFKPLVVPESADPEEYK
                     RTQAPYCLSGKVMPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSALFGY
                     SYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLF
                     NGFGDEGGRNVAVTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSS
                     IARAEYRKRG"
     gene            19321..20790
                     /locus_tag="VYO88_000022"
                     /pseudo
     CDS             19321..20790
                     /locus_tag="VYO88_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434361.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            21063..21230
                     /locus_tag="VYO88_000023"
     CDS             21063..21230
                     /locus_tag="VYO88_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718210.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEINDFMATVEVLDVKFSGTPSSESF
                     NSVAIVLVLYR"
     gene            21313..21843
                     /locus_tag="VYO88_000024"
     CDS             21313..21843
                     /locus_tag="VYO88_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718211.1"
                     /translation="MTLKTFSDKAKTFTFTYEFKDLDTAMVAGHALLGYMTGTYEVPS
                     ISITHKDKGTLVAEYVEDHKLNKTFKRICDSFKDYYNQPVDDEAFEERYKRERVLQLK
                     ESEDFENLLEKVTDYELELLDYADRLLSDKPIPMDSMTAFGTLEMLGDESISLLQKLD
                     VEVEYKGLAGYTEHLK"
     gene            21914..22417
                     /locus_tag="VYO88_000025"
     CDS             21914..22417
                     /locus_tag="VYO88_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718212.1"
                     /translation="MKRLAIETITKPMKLRGISKGIAELDGQRLEIDLDNLMIDFGGE
                     SFELDRIAGTKGGNRYFFLCPDCGRRCRLLYKRYLYFSCGTCLDIHKSTLNRSKTDCQ
                     YYWELALKEARKVEPGWSPRRGGYMFDSFPERPKYMKRDRYHKHYKKFLKYIEKGDRF
                     WLNGLRL"
     gene            23104..23514
                     /locus_tag="VYO88_000026"
     CDS             23104..23514
                     /locus_tag="VYO88_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV1718213.1"
                     /translation="MTPEQVKEKLEGVKWINKEIEGLYLELAALESGIIKKQELSNTR
                     VQTSRVNTTENNPISVLKLKEDTLQRIERLNEERMEISRLIDKLANPLERSVLRLFYL
                     NVLDAWQVAEEIDKSKTAVYIIRQKAIEHLANVG"
     gene            23670..24062
                     /locus_tag="VYO88_000027"
     CDS             23670..24062
                     /locus_tag="VYO88_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1718214.1"
                     /translation="MELDKFKTMMNVRERMTYFLRFQRMAGSENQVTIDEEAWKLVLP
                     YRWDLSGEHEKAIREGLEIFAQDINSIENKRARKYFIIHYCYMRKKTMSECVEMAATS
                     STSYHRYKQIAVLNFARIHQNGELEVYK"
     gene            24116..24274
                     /locus_tag="VYO88_000028"
     CDS             24116..24274
                     /locus_tag="VYO88_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718215.1"
                     /translation="MIEDFLIDLENIQLEDMEIDFNMDIDIDLNIDFEIDVDLDDLDL
                     TLLQELEA"
     gene            complement(24703..24897)
                     /locus_tag="VYO88_000029"
     CDS             complement(24703..24897)
                     /locus_tag="VYO88_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1718216.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(24962..26098)
                     /gene="dnaN"
                     /locus_tag="VYO88_000030"
     CDS             complement(24962..26098)
                     /gene="dnaN"
                     /locus_tag="VYO88_000030"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1718217.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTNEDFMQLITPVRTN"
     gene            complement(26257..27618)
                     /gene="dnaA"
                     /locus_tag="VYO88_000031"
     CDS             complement(26257..27618)
                     /gene="dnaA"
                     /locus_tag="VYO88_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1718218.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(27831..28589)
                     /locus_tag="VYO88_000032"
     CDS             complement(27831..28589)
                     /locus_tag="VYO88_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1718219.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIIYFSNQEEYSRIINSLK"
     gene            complement(28647..29828)
                     /locus_tag="VYO88_000033"
     CDS             complement(28647..29828)
                     /locus_tag="VYO88_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEV1718220.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            30011..30490
                     /gene="rlmH"
                     /locus_tag="VYO88_000034"
     CDS             30011..30490
                     /gene="rlmH"
                     /locus_tag="VYO88_000034"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1718221.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            30534..30607
                     /locus_tag="VYO88_000035"
     tRNA            30534..30607
                     /locus_tag="VYO88_000035"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30568..30570,aa:Arg,seq:tct)
     gene            30772..30897
                     /gene="comC"
                     /locus_tag="VYO88_000036"
     CDS             30772..30897
                     /gene="comC"
                     /locus_tag="VYO88_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1718222.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRISRIILDFLFLRKK"
     gene            30918..32243
                     /locus_tag="VYO88_000037"
     CDS             30918..32243
                     /locus_tag="VYO88_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1718223.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVIFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTITPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            32240..32992
                     /locus_tag="VYO88_000038"
     CDS             32240..32992
                     /locus_tag="VYO88_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1718224.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            33044..33115
                     /locus_tag="VYO88_000039"
     tRNA            33044..33115
                     /locus_tag="VYO88_000039"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33077..33079,aa:Glu,seq:ttc)
     gene            33121..33194
                     /locus_tag="VYO88_000040"
     tRNA            33121..33194
                     /locus_tag="VYO88_000040"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33155..33157,aa:Asn,seq:gtt)
     gene            complement(33235..33777)
                     /locus_tag="VYO88_000041"
     CDS             complement(33235..33777)
                     /locus_tag="VYO88_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1718225.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            33905..35538
                     /locus_tag="VYO88_000042"
                     /pseudo
     CDS             33905..35538
                     /locus_tag="VYO88_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(35568..38120)
                     /locus_tag="VYO88_000043"
     CDS             complement(35568..38120)
                     /locus_tag="VYO88_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1718226.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSRVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMILPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPITVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(38182..39804)
                     /locus_tag="VYO88_000044"
     CDS             complement(38182..39804)
                     /locus_tag="VYO88_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1718227.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNISELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            40010..41035
                     /gene="trpS"
                     /locus_tag="VYO88_000045"
     CDS             40010..41035
                     /gene="trpS"
                     /locus_tag="VYO88_000045"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1718228.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            41187..42665
                     /gene="guaB"
                     /locus_tag="VYO88_000046"
     CDS             41187..42665
                     /gene="guaB"
                     /locus_tag="VYO88_000046"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1718229.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSINEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(42799..43272)
                     /gene="tnpA"
                     /locus_tag="VYO88_000047"
     CDS             complement(42799..43272)
                     /gene="tnpA"
                     /locus_tag="VYO88_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEV1718230.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            complement(43452..44549)
                     /gene="recF"
                     /locus_tag="VYO88_000048"
     CDS             complement(43452..44549)
                     /gene="recF"
                     /locus_tag="VYO88_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1718231.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(44552..44920)
                     /gene="yaaA"
                     /locus_tag="VYO88_000049"
     CDS             complement(44552..44920)
                     /gene="yaaA"
                     /locus_tag="VYO88_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV1718232.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEPDEYQADKVEKEQIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            45079..46329
                     /locus_tag="VYO88_000050"
     CDS             45079..46329
                     /locus_tag="VYO88_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1718233.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGYMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            46326..47609
                     /locus_tag="VYO88_000051"
     CDS             46326..47609
                     /locus_tag="VYO88_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1718234.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            47651..48472
                     /locus_tag="VYO88_000052"
     CDS             47651..48472
                     /locus_tag="VYO88_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1718235.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVTLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            48483..49028
                     /gene="pgsA"
                     /locus_tag="VYO88_000053"
     CDS             48483..49028
                     /gene="pgsA"
                     /locus_tag="VYO88_000053"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1718236.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            49025..49852
                     /locus_tag="VYO88_000054"
     CDS             49025..49852
                     /locus_tag="VYO88_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1718237.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            49837..50676
                     /locus_tag="VYO88_000055"
     CDS             49837..50676
                     /locus_tag="VYO88_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1718238.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRIFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            50669..51463
                     /locus_tag="VYO88_000056"
     CDS             50669..51463
                     /locus_tag="VYO88_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1718239.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            51522..52340
                     /gene="mreC"
                     /locus_tag="VYO88_000057"
     CDS             51522..52340
                     /gene="mreC"
                     /locus_tag="VYO88_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1718240.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTVVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            52340..52834
                     /gene="mreD"
                     /locus_tag="VYO88_000058"
     CDS             52340..52834
                     /gene="mreD"
                     /locus_tag="VYO88_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1718241.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            52928..54106
                     /locus_tag="VYO88_000059"
     CDS             52928..54106
                     /locus_tag="VYO88_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1718242.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            54330..55109
                     /gene="rpsB"
                     /locus_tag="VYO88_000060"
     CDS             54330..55109
                     /gene="rpsB"
                     /locus_tag="VYO88_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1718243.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAALETQADSIEEIVEVVEGDNA"
     gene            55188..56228
                     /locus_tag="VYO88_000061"
     CDS             55188..56228
                     /locus_tag="VYO88_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1718244.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKSQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            56474..56814
                     /gene="tnpB"
                     /locus_tag="VYO88_000062"
                     /pseudo
     CDS             56474..56814
                     /gene="tnpB"
                     /locus_tag="VYO88_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(56847..57155)
                     /locus_tag="VYO88_000063"
                     /pseudo
     CDS             complement(56847..57155)
                     /locus_tag="VYO88_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            57146..57544
                     /locus_tag="VYO88_000064"
     CDS             57146..57544
                     /locus_tag="VYO88_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1718245.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(57741..58661)
                     /gene="cysK"
                     /locus_tag="VYO88_000065"
     CDS             complement(57741..58661)
                     /gene="cysK"
                     /locus_tag="VYO88_000065"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1718246.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGATDVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(58946..59581)
                     /locus_tag="VYO88_000066"
     CDS             complement(58946..59581)
                     /locus_tag="VYO88_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1718247.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            59637..60935
                     /locus_tag="VYO88_000067"
     CDS             59637..60935
                     /locus_tag="VYO88_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1718248.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            60932..61594
                     /locus_tag="VYO88_000068"
     CDS             60932..61594
                     /locus_tag="VYO88_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1718249.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            61674..62222
                     /gene="raiA"
                     /locus_tag="VYO88_000069"
     CDS             61674..62222
                     /gene="raiA"
                     /locus_tag="VYO88_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1718250.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            62358..64331
                     /locus_tag="VYO88_000070"
     CDS             62358..64331
                     /locus_tag="VYO88_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1718251.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            64328..64780
                     /gene="rplI"
                     /locus_tag="VYO88_000071"
     CDS             64328..64780
                     /gene="rplI"
                     /locus_tag="VYO88_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1718252.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            64824..66176
                     /gene="dnaB"
                     /locus_tag="VYO88_000072"
     CDS             64824..66176
                     /gene="dnaB"
                     /locus_tag="VYO88_000072"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1718253.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            66178..66444
                     /locus_tag="VYO88_000073"
     CDS             66178..66444
                     /locus_tag="VYO88_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718254.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            66533..67879
                     /gene="cbpD"
                     /locus_tag="VYO88_000074"
     CDS             66533..67879
                     /gene="cbpD"
                     /locus_tag="VYO88_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1718255.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      67962..68064
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            68135..68425
                     /locus_tag="VYO88_000075"
     CDS             68135..68425
                     /locus_tag="VYO88_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1718256.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            68388..69146
                     /locus_tag="VYO88_000076"
     CDS             68388..69146
                     /locus_tag="VYO88_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1718257.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            69184..70191
                     /locus_tag="VYO88_000077"
     CDS             69184..70191
                     /locus_tag="VYO88_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1718258.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            70191..70919
                     /locus_tag="VYO88_000078"
     CDS             70191..70919
                     /locus_tag="VYO88_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718259.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLHLTTLIITHSIEEALNISDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            71038..71496
                     /locus_tag="VYO88_000079"
     CDS             71038..71496
                     /locus_tag="VYO88_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1718260.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            71498..73930
                     /locus_tag="VYO88_000080"
     CDS             71498..73930
                     /locus_tag="VYO88_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1718261.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGNTLKI
                     GVKAGQLKFDIA"
     gene            74572..75225
                     /gene="rr06"
                     /locus_tag="VYO88_000081"
     CDS             74572..75225
                     /gene="rr06"
                     /locus_tag="VYO88_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1718262.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            75222..76553
                     /gene="hk06"
                     /locus_tag="VYO88_000082"
     CDS             75222..76553
                     /gene="hk06"
                     /locus_tag="VYO88_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1718263.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            76636..>76839
                     /locus_tag="VYO88_000083"
     CDS             76636..>76839
                     /locus_tag="VYO88_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718264.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGM"
BASE COUNT        24189 a        13160 c        15303 g        24187 t
ORIGIN      
        1 ctaaactgca caaaaaagag aggctccagc ctctctcagg gttatttttc gtcattcatt
       61 tttgacttta cttcatcata ggatagtgca tgagattcct cttctactgc ttcaggcatc
      121 tttcctgttt cgtaaagagc tttaatttgt gtactatcca atgtttcgta tttcaataat
      181 gcttctgcaa ttaacttgtg agtttcacga tttgactgaa taatttcagc agctttattt
      241 cgtgcctcat ttaataatga acgaacctcc tcatcaattt cataagctgt ttgttctgaa
      301 attgattttt gaggactctg tgcaccaagc atagcatggt ttccttcata ttgtactggg
      361 ccaagttttt cactcatacc gtactctgta accattgcac gtgccatttg tgtcgcttgt
      421 tcaaagtcgt ttgaagctcc tgtagtttgg acattaaaga taatttcttc agctacacgt
      481 ccacccatta agccagccaa ttgctctttc atatcttctt tagatagaag catttgatcc
      541 tctttaggaa gtgcaatcat gtatccgcct gcacggccgc gtggtacaat tgtaacctta
      601 tggacaacgc gagcattcga caagactaga ccaacaatgg tatgtcctgc ctcatggtaa
      661 gcaaccaatt ctcgttcttt ttgtgaaact gtcttatctt tcttagaagg tccagcaata
      721 actctatctt ctgcttcatc aatatctgaa gcatcaatta tcgatttatt gcgacgagca
      781 gcaactaaag ctgcttcatt caagacattc tctaaatcag caccaacaaa gcctggagtt
      841 tgttgagcca ctaatttcaa atcaacatct tctgctaaag gcttgttctt agcgtgaact
      901 ttcaagattg cttcacgacc tttaacatca ggacggccaa ccaatacttt tctatcaaaa
      961 cgtcctggac gcaaaagggc aggatcaagt acatctgaac ggtttgtcgc agcgatgacg
     1021 ataatccctt catttccctc aaaaccatcc atctcaatca aaagttggtt caaggtttgt
     1081 tcacgttcgt cattacctcc gccgagaccg actccacgtt gacgtccaac agcatcaatt
     1141 tcatcgataa agatgatagc tggtgctgct tttttggcat cctcaaaaag agagcgaaca
     1201 cgactagctc caactccgac aaacatttct acaaagtcag aacctgagat actaaagaat
     1261 ggaacacctg cttctccagc gactgcctta gcaagcaaag ttttacctgt ccccggaggt
     1321 ccctccaaaa gaacacctgc tggaatacgg gctccaagtt ttgtgaatcg ttttggatct
     1381 tttaagaact caacaacttc aactagttct tgtttttctt cttcagctcc agcaacatct
     1441 gaaaatctta ctttaatatc ttctttattt gctgctttag ccttactacg tccaaaactc
     1501 attggattac ggccattgcc tcctcccata tttcccatca tagagaatag gaagaagaat
     1561 agaattccaa atggcacaat ggatacgagt agattaatcc atataccact tgaactttca
     1621 tgcttaacag ttacttctgc tttatggtca gtagcaagtt tttgcaattc tgatacggta
     1681 gtatctgcag gaagaatagt gctggtaaat ttctctacct tagtaacaga tggcgtgaaa
     1741 aactgaatac ctgttccttc tttacttgtt ttaggatttt tatagacacc agaaacttcg
     1801 ataacactac catttggttg gtaagttaat tcttttacat taccatcggt aatttcttgt
     1861 accaactcag tatagttgat ttgctgactt cctcctgagt tattcccaga atagaaatac
     1921 tggaatcctg tcacaaggaa aaagataaat aataaccata gaaaaggatt tttaattaaa
     1981 ccattatttt gttttttcat taaagattat tctttctaat ttgaatacac ttcctctttc
     2041 aatactccaa tataaggaag attacgataa ttttctttgt agtctaaacc ataacctact
     2101 acaaactcat ttgggatagt aaagcaggta tagtctgcct caatttctac aacacgtcct
     2161 tctggtttat ccaacaaggt tgcaatttta acagaagctg cttctcttgc tttaaacata
     2221 tctcgcaaat tcttcaaagt ttgacctgta tcaatgatat cttctacaaa tagaacatgt
     2281 cttcctttga tatcttgagt cacatcttgt ttaatattga taacaccact acttgctgtt
     2341 ccaccatggt agctagaaac catcatgaag tccatttcaa tatgtgtatc aatatgtttg
     2401 accaattcag ccataaaagg aatagatcct tttaaaatcc caactaagat tggatttttt
     2461 cctgcatagt ctttagttaa ttgagcacct agttttttag ctgcttctgt aatttcatcg
     2521 tgtgaaacga ggactttttt aatatcgttt tctaacattt tttacctatc tattttttct
     2581 atataaagta cagtgttcat tatatcattt ttcgtttttt tactcaaatt attggtcgca
     2641 attcccaaaa ttgagacaat ttcaccaaat tgctcaataa taagagcaga gtttctcttt
     2701 tccataggga ttttcaaatc aataaataaa cgtctgagtt tttttctatg cccattttga
     2761 atcaaaacat ctcctgtttt tcgatgacga atgtgtatgg atgtttcacg tgaaacaggt
     2821 atttgttgaa ttaattcacc ttctaatgga agtccaaaag aaaataaata tccttgataa
     2881 gctacctgat tttgatagtg taacacaagt tcatcttcct tttcatcagc ctgcggactg
     2941 attttacaaa tctgaaactg ttggtactct tttatcaatt catagccatt tttaatcgga
     3001 tgacgatact ggcttttaga ttttaaaatc tgctgaactt cagcaaactg agcttttgta
     3061 agattcaaat ctggaaaacg attcagataa gtttgaagta aaactctttg tgtagactca
     3121 gagtaagaaa ataactgctg taaattttcc acatcaatat tgttagataa ttcagctatt
     3181 gccaaatcat aatctaaaat ttcattgccg atgcctaaga ttgcatccct aaatcgagga
     3241 ttttcttttt ccaattctgg taagtaagag tttcgaatac gatttcgaaa ataatgattc
     3301 tcctgatttg atgtatcttc aaagtgaaaa attgatggaa agtctttttt ctgaaaatgc
     3361 aagaagggac gaatgatttc tatctctccg actacttgct tctccttaat tcctgataga
     3421 tagcgcaagc gagttcctcg aatcaagcgc atcaaaatcg tttccacctg atcatcagca
     3481 tggtgggcag tgactaaagc tgtcgcacct gtctttttca tgacctcttg aaaaaaatca
     3541 taacgaaaat ttcgtgcacg cgcttctgaa aattctcctg aaaaattgct gatataaata
     3601 ggaagttctg cttcagcagc caacttcctt aattcctttt cttcccaatc tgattcaatt
     3661 ctctgcttat gattcacatg agccagaatc aattcaatct ctaactcttt ttgataagta
     3721 gacaatacct taaatagaaa catagaatct aatccaccag aaagagctag aaccgcctta
     3781 gcatgctttt tgaaatatcc cttcttgaga aaatgattta aaaaatcttg ttccctcatt
     3841 ttagaacctc ataaacatcc ttggctatct tagaaatcgt atcataatca gaattcttag
     3901 tgaaaataga aagaataaat ggagaatctg catagacaac acccgtatca tgcttaaatt
     3961 catccgcatc tccaatttta tgagctactt taacagaaac acctttggca attcgctgac
     4021 tatcaaaatc tgttttagtc aaagactcta gcacaaatcc attttgatta taaatagctt
     4081 ccataaactt cccggccatc ttagaagaaa tcaatttttc ttttggatcc caatcatctc
     4141 ccataatggc agacattttg gatttgaatg tggcatcaga ttggtttgaa atgtaatatc
     4201 ccaatagatt atgagctaca ttatcagatt cttttgatac tttcgtaatt aaatccttta
     4261 aagaatattc tttattatct tcttttttag gaagactacc acttccctct ggtttataag
     4321 aacctggaaa atcattgact gcagatacgt attttacagt cgtatctaac tgataaagac
     4381 cctcatttat tttttcttgc gtataataga gataggagag tttcaaaacg ctggctgcat
     4441 acatcttttc atcttgattg ataccagctt cttttccagt agtcagttgc ttaacataaa
     4501 tagagaaaga atctttctga tatttttcag ataacatttc ttgaacttta ctcatccgat
     4561 tatcttcttc agaagttgat tctttagcta cccatccagc ctgatcaata tgtagaaatt
     4621 ctcttccttc tacaaacatg gtcttatcga ttgatacttg cgaataagct gataaggatg
     4681 atttcacttc ttttaaatca taaggactat tgtacagttt aaagtcagat tctaaccata
     4741 ctttttttat tgttggagtt acctctgatt gatcatataa aaatcgtttg tccgcagcta
     4801 taaattgatg atttgatagc ttaaatactg gaattccttg tttatttaag cgccactcgg
     4861 ttatttgaaa acttgttttg ggagtcaatt tcccagattc cactactaaa tcttcattcg
     4921 cataaacagg aacctctcca taaaccatgg gaaaacttaa tttttctcta aaataaatac
     4981 caaagtcaga ttgtgaaagg taataaattt ctttcgaagt atagacgact tctttttctg
     5041 tgctaacaac ttttgaaatg gtcaaaaaac ttggtagcaa caaaataatt aagaatttac
     5101 gcattcttcc tttccttttc ttcttgtaaa cgcaataatt gatttttatc agccaattct
     5161 tccagctttt catctgacaa actcaaaaat tgctctatta cgtctaataa attttccatt
     5221 ttatcacctt tgaagcaagt caggaatcgt ataaactttt tccctcgact tagaataata
     5281 gtacttcgct cgtgtatatt tggcagcata atcttcatct ttcaacttgg tagcaaatgc
     5341 tgtttcctta tccttttcat cactcaaagt ttgatactga gtttgcaagt ctgctaattg
     5401 ctgacgtctt tggagtaatt gctgataact ctgcgctaaa ttaaaagttg gcaagataaa
     5461 taatagcata atcaaaatca ataccccccc cataaaacga ttccgttttt gtcgttcttt
     5521 catcaggtag cgacgacgtt ggtattcatt ttgaataaaa gaattattca attgtacaat
     5581 atttttagac attttcttct acccgtgttt cactgataat ttcatacatg cctgctgcat
     5641 cttctttttt tgtactatct ttcatctcta gtacttttac aagcagcaac ttattgccaa
     5701 agcgaatttc aacttggtca ttaactttca agtccgttga acttttggcc aagattccat
     5761 taaccttgat tctaccttta tctgctactt cctttgcgac tgtacgacgc ttgataattc
     5821 gcgatacttt taaatattta tctaatctca tccttattac ctcaatttat tattgtacca
     5881 tttttatcta ttttatagaa gaaaaatatc aaatggaatt ttcttcctta aactctttta
     5941 tctctaataa actttctcca aaaatcagca gaccttctaa aatttcataa tctttcttat
     6001 tttggacatc aaatacaagc tccattaatc ccttattctc agcgatgcct gcttttaagt
     6061 tcgttacgga taaagcttta aaataatctt gagctaaaaa cagtcgttga gtgacttttt
     6121 caaattgaat tgtaatttta ttatcttttc tttccacacg ttgaacaaag accttgtcca
     6181 agtatgattt aaccaaacca atctctaaaa gataggctac tacatctggg tattctccaa
     6241 aacggtctat caactcctct tgtaactctt cataattgac acggttgtca atttgacgaa
     6301 ttttcttgta aatttcaatc ttatgtcgtt gatcagaaat ataagtatca ggaagatagg
     6361 catcaatttg caaaaccaac tcagcattcc ctttggttct tgtgttagcg ttagcattac
     6421 cgtttcgttt agcaatagct tcctctaata actgcgaata caattcaaaa ccaacagaat
     6481 caatgaaacc agactgggat tttcctaaaa gatttcctgc tccacgaatc gaaagatctc
     6541 gcattgcaat cttaaagcca gagcccaatt ctgtaaatcc tttaatcgct tctaatctct
     6601 tttcagagac ttcactgatt gatttttctg gacgatacat gagataagca taagcaatac
     6661 gattactacg accgactctt cctcttaact gatataaggt tgacaagccc atatggtccg
     6721 cattttcaat aaataaagta ttagcatttg gaatgtccac ccctgtctca ataatagtag
     6781 tcgtcaccaa gatatcgtat tgtccctcaa taaagtctaa tagagtattt tccaactgga
     6841 cttcactcat tcgaccatga acatatccaa tcgaagcctc cggaatcaac tcctgtaatt
     6901 ctgaaacctt ctgaacaatt gtatcaactt tgttgtaaag atagtaaact tgacctccac
     6961 gctccatttc acgcaagaca gcatcacgaa tgacactatc attcttttcc aaaacatagg
     7021 tctgaacagg atagcgatta gtcggcggag tttcaataac agacaaatct ctgattccca
     7081 gcatagacat atggagggta cgagggattg gcgtagcggt caaggttagg acatccactt
     7141 gtttcttcag ttctttcaaa gtttccttat gcttgacacc aaatcgctgt tcctcatcaa
     7201 taatcatcaa gcccaaatca gcaaacacaa catcttttga caaaacacga tgtgttccaa
     7261 tcaaaatatc gacttgaccg tttttcaatt tttcaagtgt tgcagtctgc tcttttttac
     7321 ttctaaagcg actcaacaca tcaacattaa ctgcaaaatt ttggaatcgt tccttaaaat
     7381 tcgtatagtg ctgttgcgct aaaaccgtcg tcggaactag aatgacaacc tgtttgtgat
     7441 cattgactgc tttaaaggct gcacgcatag caacttcagt ctttccaaaa ccaacatccc
     7501 caactaaaag tcgatccatt ggctgagaag cctgcatatc cctcttgatt tcctcaatac
     7561 tacgaagttg atcatccgtt tcaacataag ggaaagcatc atcaaaggca tcttgatcat
     7621 catcatcagc tgagaaagca aaacccttca actgactacg ttcagagtag agtttgatta
     7681 aatcatcagc tatatcctct acctggttct taaccttttg cttggccttt ttaaaatgac
     7741 cgtcatttaa tttattgagt tttggagctt taccatcact tgaaatatat ttggacagta
     7801 gatgaatctg ttccacgggg atagaaattt gatcaccatt ttggtattgg acactgacat
     7861 aatcgcgatg aattcccttg atttcaatgg tttcaattcc tagatattga ccaatcccat
     7921 ggatatgatg gacaacatag tccccttttt caagttcatt gtaatctttt aatctctctg
     7981 catttgaaac atgttgtctt cgaaaacgac gctttaattt cttttgaaaa atctcatgtt
     8041 cagttatcaa taaaatcttt tcatctacaa aatgaaaacc atgtctgaga ttaccctcta
     8101 ttaagtttac agattcttta cagatacttg tcttatctct agaatccaat ttaatctgat
     8161 attcctctaa catatcctcc aatgttttac ttcccattga attgctagac tgcagaataa
     8221 tggtgtaatc cattttttta tatcgttcaa tttcttcttt tagaaaagaa aactgattga
     8281 aaaattcctg cataggatat tgattgaatt gataaatttt gtcaaatttg agatttccta
     8341 aacccttttg aagattagag aaaaaggtca ctggactttg ttttttatag atttgttcaa
     8401 tatcagaaaa atactgcata tcagaaaatg ctttactatt ctgtaattct tctgtaaagt
     8461 actgcgctaa gtctctttca aagacttcat actgattcat caatttttga taatcatcaa
     8521 agaatattgg agtatctttt tcaatataat caaagacagt ccatgtctta tcatagcaca
     8581 aagataaaaa cttccgagag tctgcatgac tttgtttttg gtgaaaactt gaaagaattt
     8641 cttctaggta tgatttcaaa ataggtgata aagtttttga aatttgtttt tctaaagctg
     8701 actgtcctcg ttgataatcc ttttctctca aaagcatatc actagctgga aagatagtga
     8761 gttctgtctt attttctttc gataattgtg tttctacttc aaatgacctg ataccatcaa
     8821 tttcatcacc aaaaaactca attcgacaag gttctaactg ggatatttca aaaatatcta
     8881 aaatatctcc tcgaagacta aattcgccct gagtttgtac ttgagtaact tttcgatagc
     8941 cattttcctt taactgatgg ataaacgcgt gttgatcata ttcttcacca actgagattt
     9001 ttacaatact atctttgaat gcattgggag acggtaaaat caatcgactt gctgcgatat
     9061 tacaaactaa aatccctttc ttagatgaat cagtcaaaaa acgcaaggct tcaacccgtg
     9121 aaataatttt ttcctgtgaa gacatcaaaa actccaccat aggagcatca tctaccaaaa
     9181 atggatagac gagttcctca cccaagatag aaataagatc actaacaagt ccttctgctt
     9241 ctccataagt tgacgtcaat aacacaatcc tatcttcttt ttctaaactg cttgcaattg
     9301 caagagcctt agtagatgtt gataaaccaa gtattagttg tcttttctta tctgttaaat
     9361 tttgatgcca ttttttaatc tgatcatttt ctgagaataa atctaataag gtcaccattt
     9421 atccgttata cctctgcatt gttttctcaa aatttttctc ttgtaaatag tattttacag
     9481 aatcgtcaac tttgtcaaca gactgtaaaa taccgatata atcatccctg tcaaacttac
     9541 tcaaaacatg atgaacaact gacataccat ttttaggtct tccaattcca atcttaacac
     9601 ggttaaagac ctgagttcct atatgttgaa taatagactt gataccatta tgaccacctg
     9661 ctgagccttt tgctcttaaa cgaattttcc caacttccat gtcaagatca tcgtaaatga
     9721 taagtaaatc gtcaatatcc aaaccatagt aagttaataa agcatgaact gcttttccac
     9781 tttcattcat aaaggtcgtt ggtttaacca gataaatttt ttctccattt aggaaaaagg
     9841 atgctaggtc agcttgaaat atcttatcgt gtgtaaaagt gacattctgt ttcttcgcta
     9901 gttgatcaat caacataaaa ccaacattgt gttttgtttc aaaatattta tcccctggat
     9961 ttcccaagcc tacaagtaat ttggtcattt atttttcctt tcaaaagcca aaagggttgg
    10021 aatttttttc caacctaatt gacaccattt attaattttt agacattaaa gcggaattcc
    10081 atgatatcgc catcttgaac gatatattct tttccttctt cacgcaagcg tccagcttct
    10141 tttacggcct tttcagatcc gtatttcact agatcttcat atgacatggt tactgcacga
    10201 ataaagcctt tttcaaagtc tgagtggata ataccagctg cttgaggagc cttcatacca
    10261 cgtttgaaag tccaagcgcg aacttctttt tcaccagctg tgaagtaagt tcccaatcca
    10321 agcaagtggt aagctgcacg cgtcaactta tctacacctg attctgtcaa accaatggct
    10381 tcaagaaact cttttttatc ttcatcatcc aattcagaaa tttcttcctc agcacgcgca
    10441 gaaataacga ctacttcagc attttctgtc gctgcaaatt cacgaatttg tttgacatag
    10501 tcgatagagt caggttctga aaccacatcc tcgtccacat tagctacata aagaactggt
    10561 ttagtcgtca aaaggaaaag acctttgaca accttttgtt cctcatctgt aaattcaatg
    10621 gtacgagctg atttcccgtc ttctaggact ggtttaatct tttgaagaac attgaattct
    10681 gctactgatt ctttatcttt ttgcgtacgt gccatctttt ctacacgcgc atatcgtttg
    10741 ttcactgatt ctaagtcagc aagaattaat tccagattaa ttgtatcaat atctgcaagt
    10801 ggatctacaa aggcgtcttc acgtccttgc tcgcgcatca cattttcatc atcaaaagca
    10861 cgaactacgt gaacaatcgc atctacttca cgaatattgg ccaagaattt attccctagc
    10921 ccctctcctt ttgaagctcc ttttacaatc cctgcaatat ctgtaaattc aaatgttgtg
    10981 ggaactatct ttttaggagt tatcatttca gttagttttt gtaggcgttc atctggaact
    11041 tccaccattc caacatttgg atcaatcgtc gcaaatgggt agtttgctgc ctctgctcct
    11101 gcttttgtaa ttgcattaaa tagtgttgat ttaccaacgt ttggcaaacc aacgatacct
    11161 gctgtcaaag ccatatttct cattctccgt tttcatttca atccctaata ttataacaca
    11221 aaaagggtaa acttgctaaa attccttgat atagctattt cccataactg aaataataat
    11281 tttatggact tttttaggaa ctttttaatt tttcaatagc tttttcataa aatgaagtag
    11341 catttttctg attgtctttg gataggtggc tataaatatc catggtcata gaaagttttg
    11401 catgaccgag ccgtgtttgt atctctttgt aaggtagtcc agcattgagc aagatactag
    11461 catgagtgtg gcggaaggcg tggaacgtaa aacgagggca tccagcacgt tccaaatgtt
    11521 ttactaacct gaaactaagc attctagcgt ctatatgctt atcaaagcta ttagagaata
    11581 ctttctcata ggtcaacccc atttctttcc ctatttggga ttgtcttgct ttatagagcc
    11641 gtagcatgag caccgtctta ttatccaagt caattaccct aatacttgat ttagtcttag
    11701 ggccagtgat ttctttgata atatttaacg ttttatttac gtctagtgtg ccgtttttta
    11761 ggtcaatatc agaccactct aaggctagac actcacgaat gcgcaaacca gtcgctaaaa
    11821 gtgtcttata tagcaccgta tcgtagaaat ttttgtaagt gtttggcagc tgctccaggt
    11881 aagtcaagaa tttttttaag ttatcatcat ccagatattt cagtttttgc ccttcttttt
    11941 ccttacgacg tggcacgata acatcacggg cagggttaaa ggggatagct tgcaaagata
    12001 cggcatattt aagtatgcgt ttgtttagag agtgaaggag cggatattct tggaatcctt
    12061 tgcctagttg attatagtct tttgcccatt gattgacttg cttttgaatg attgggggcg
    12121 tcagtttatc cagcctataa tttccgaaag ctggaagtag atatttatct attttgaatt
    12181 tggtacccat taaggtcgat tttttaaccg tatggcagta cgtttctagc caattctcca
    12241 ccagttcggc gtaagtcttt atctcaaccg ccttatatac tgtagaccct cctttttcaa
    12301 agtctatttg agcctgtagc gctttggctt tgagttctct cttggttcgc cctgatatag
    12361 tcgtcttgac tttcttacct gttacggtat cgataccaag gtagacgcta gagcgataga
    12421 ctgtagaacc gtcttttttg gtgtattctg ttattttcat gatgataaac ctttctaaaa
    12481 tacatcagca ggcaagctat tattaaaaag gttttagatt atggtttata tcatgttgag
    12541 cttacgggaa agattttatt tgttattttc ttcagctaaa gctatctgta caagtttttc
    12601 ttttactttt tcagtgagtt cctcatagta gagaattgaa gaaataattt cttttaaaaa
    12661 attgaaatcg attaacccca ttgctaccca taagacaata ttttccattg tttcgataaa
    12721 gaagggaatg aggtaatcaa ggtgattgat tgttaaaaat ttaataccga agacaatgct
    12781 acttctctta tttccatcat tgaacatatg aaattgaact gtattaaata ctagcactgt
    12841 aagttttgtt tcaaagtctg gatagtaatc gtcattctgt aagtgttcaa atacactaaa
    12901 tacccttccc ttatctttaa caccgtgtaa accacctatt ttctcaatta cttcaatgtc
    12961 gtgtagtaaa attgcttctt cagcagaaaa ataattgatt ttatccatta tttatctctc
    13021 aatctttcaa aaacttggcg gtgttcatca atttgttccg aaagtgattt actttgttcg
    13081 ccaataaatc tttcaaaatc ttcttcagaa attggacgga tatattctgc taatttctca
    13141 tgtttggcat tcctgaaaga tagatcccta ctagccattt tctctctggc atgcattaaa
    13201 tggggttctt gcattgggtg atttgctaat ctctgaatta tctcgattac atcagtatta
    13261 gttagttttt gatttgaaga cttactcttt tgttcaatct cataagcaac ccctttctca
    13321 aaactagcaa taactataag tacctcacta tacattgttg cgcgagcatt atcattttta
    13381 ttcaatttca gtattttttt atattctgat gctctttctt taaagattgc tttgtaaatt
    13441 tcattcgtta attgaccata tttaaaatta cttccagaga catacttatc aatggcattt
    13501 gtaaatattt ttctagcatt atcttcttct aatgcagtcg atagataatt tttgtcacgc
    13561 tggtttataa attttacatg gccaccagtc ttctcagtta acacattaat gacaatatca
    13621 agtagggtat ttcttacttg cttagctata tcactattgg ttaacaacat agcaaaatta
    13681 agcaatgttc tgaacgatga gatacttaat tgtgtaactt tgctaccgac atttgtgtcg
    13741 gtagcaaaag cattttcttt aaatttagct agtttttctc cacgtaaagt gtgataacca
    13801 ttttcagtaa gctccgtttt atgagcttca acaagtcttt caatagttcg aatgtcgact
    13861 tcgaaaaagg tagctagctg agaatttgta aaataaaaag tatcctcaaa gtagaaacca
    13921 ggtactttta aaatctcttc agctttttgt aatgctaaag aattatttaa aatattttgt
    13981 ctttctattt gtgaggttgt cagatcagtc ataatttctc ctttttgtcg agttaatttg
    14041 ccaataactc ccgatatttc aagagtttta ttttattttc gtgtcgttag agtatattag
    14101 aaaatcttga actccgcgaa tacacgcgct tcaggattgt tgaacattgt ggcgcgtggg
    14161 ttagtcgctg aagtgttccc tgatttcttc agctaaatca ttcaagcggt tctgaatacc
    14221 tttatagtaa tcaaattcaa tggtgtcaat gatgtcactt ttttcagtaa atatcttgtt
    14281 ttttgtaaca caaaagctat tatttgtatt attgtgaaca aggtcattta tctcattttg
    14341 aacagaagat attttccttt gtaagcaata gcctaagatt tttcgatctt gaatacctat
    14401 tttttcaatt atttcattca cttcaaagac aactgcccca tagctatcaa ttttattgtt
    14461 aaggctattg ataagattag aaatttcaga atgcacatag gaggtattga gagcttgctc
    14521 acgttcaata acgtttatta aacgtgtaat atattcgtta gtaatcatgg tgagtacatt
    14581 attataagcg tactccctag cttcgcgctg tttggaaagt agtagagcct cattattttt
    14641 tgagatatct gataaatcaa gtccgttgaa aatttcaaca ataccagggt ttattattga
    14701 agactgaaga acgcgaccca aaacaccctg gtcaaatgct atttttcctc gaatgtactc
    14761 catattcata taatcttttt taaagctaag tatttctttg attttattga agaacatctc
    14821 aaaaaccttt tctctttgat tattatctag caactctttt agtgtgctgg ttgaaactgt
    14881 atcaataaac cgcagatcta ggaaagattt ttttacgttc aaaaaatcag ctattttttg
    14941 taaattccca gcggttggta aagattttcc ttttacatat cccgtaattg tacttttagg
    15001 aatatctaaa gcgttatgaa ggtcaatttg tctaacccct ttttgttcca taagaaggtt
    15061 gagccgttta gagaagtatt ctctattttc aagatcttga ggactatttt tagccatgac
    15121 tttaaccctt tcagttgtaa gttatacatt gattataaca caaaataaaa acaaagtacg
    15181 aaaataaata aacttttttc taaaaacact tgactaagta cgaaaaagat agtacatata
    15241 taccgtttga acttttaaaa gaattgtctg caatttacca agttaaattg gacaatattt
    15301 ttttaggaga tagtacgaaa aaaatagaac taaataaaag agagttgcaa taatgagagt
    15361 attattttaa gtcaatggtg gcagaaatca aaccagacat aacaatagat gaattatttt
    15421 atagctagaa aggagcaaac caatggaact agtctatatg gacggtaaaa aagagccgta
    15481 tacactgagc agtattgtgg cagagtgtgc agaagtcaag cacagacatt tgaagatttt
    15541 gctaaataaa caccgagagg acttcgagag tttcggaaag gtgcaattta aaatttcacc
    15601 ttcagaaagt gggcaaaatg tacgggacta tattttaaat gaacaacaag caacattgct
    15661 gatcacttac ttacgaaata cagaacccgt aaaagagttt aagaagaacc tagtcaaagc
    15721 attctttgaa atgcgtgagg aactttctaa gtttcgtatg cagagggcgc tagaaaagcc
    15781 aaaaagaaaa accttgcatg acagtattaa aacatgggag gcaaaaccca agcacgcgca
    15841 tagcaccatg aacaacctgt tactgaaggc agtaactgac atgaacgcta agcagttagt
    15901 aaaaagccgt gggggctata atggcattga tagcttgacc agtgacgagc tggagcaata
    15961 ccaggcattt gaggatatgg taatagccat gattggcttg aatatgagtt atcaggaaat
    16021 caaagctatg gcattcagaa ataaaaaaaa cacgccaaag aagcgtgtga gagcaacaaa
    16081 aaaggcttag caataaccac accgcagagc ctttcacact aacactaaaa cgaatttaac
    16141 aaaaagcagg caagctatta tcaaagaggt tttagtaaag atttatacct agattatagc
    16201 atatttaggg caatttgacc atacggagag cgccaactct ttaaactggt actttctcac
    16261 gctttcaatt tggcgagtct gagcgtgagg ctagtactta caagaaaaaa ctgtataaga
    16321 aacaactcaa aaagccccac gctcagaagt ttggcgaccg agagcatgag gctgtaggca
    16381 agaaaaactg tataagaaac aaccattcaa aatccccaca ctcgccatcg ctcaactttg
    16441 agtgtgagga tcagcatgta tagtaaaagg tattaaatgg cccttagggc aactacacaa
    16501 catagaaaca gaggtaaaaa catgacagaa acaacatacg agaatttaac tagacgtata
    16561 aacagaatta gcgcagaaat gcaagaaatt ggcgaaaaaa atgggcttag tagactttcg
    16621 ttattggcaa gtcagacaaa attcatcaaa gaagaattat cccgtttact ttggattgaa
    16681 ctccctgaat tgaatgacag ccataaaatc gaagcggtct ctaaaagcac tacgggaatg
    16741 tttttccacc ctggtatttt tgaaatggac gctatgcgac aagcattctt taaacgccaa
    16801 gctatgcact tttttgagaa cgaagcagag caacaggcgt atatagaaca tgctgaaaag
    16861 gagtatttag aggctactat aaccttaaaa gatattcttt ttaactctaa aaatggaact
    16921 cagagagtaa ataaaagttg tcttatagag aagtttgagg aggcaatgca atgacactag
    16981 acctagacaa catgacacaa gcagaatttg ataaacaaat ggctgaaatc aaggagagaa
    17041 atccaaacat ttttcaactg atttctgatt ttttagatag aaaggtaaca cccgaagagg
    17101 tggatgagtt tttgaagatg gagcgagctg aacaagtgga atatattaag aattatcaag
    17161 cgagggtata acatgaatga gctagatata agtaacacac aggctgctgt cttaatcgtg
    17221 attttgattg gcttactgct ttatttaaac caccgagacc gcaaaaaaag cgcccaaatt
    17281 gagcgagaaa accaacagac gataaaaaca cctagcgagg atttaaaccc tgattatggg
    17341 cgatatatcc agcttgcagg agtcaacgta tggggaggga tggaatgagt tacacaatga
    17401 atttataccc cgatattgaa aaaataccag atgaaaccta ttttactaaa gagatttttc
    17461 tagcaacgtg cttgaataac acaatcagaa tagcagtagc cagaggagtg ctaacatctc
    17521 aacttttaga caaagaaact aaagaagttg tttgtaaaac cttggataca atcatagaaa
    17581 atcaaaaagc tattttgcaa ggggtagcga gcggacaaat aacctttgta aataaaagca
    17641 aaggagagga ggggttggat gagtctatca gagaatgaca agcgagtttt aagactaatc
    17701 aaggtagggg ctgagaactc cataacaggg tcagaaatta gcctgacaac caagctaaca
    17761 gaaagaactg tacgtgacat tatcaagcgt ctagtagtta agcacaacat ccctattgta
    17821 ggggttagat gtggcgtttt tagtgggtac tttattccag cgaataaagg cgagttacta
    17881 gatggcgcta aggcttttta caaccaagta caggaggaga gcaagcgcct agcggtgttg
    17941 atgaatagcg acctagaaag ctacaaagaa accttgaagg aggtgggcgg atatgtttag
    18001 cctaagccga gaaagcgagc aagacctagc gcatggcatt ctggaggtag tggaaagata
    18061 cctggaagcg cgtgagaaag taccgccaag attgaccaag ttaataaata gagttgaact
    18121 caaagaggaa ttgaaaatta gtgacaacac gctgaataag tgggaaagtc agggtttaag
    18181 acgctatcaa ccgccggacg atggtactag aataatattt tatttagtgg atgacattcg
    18241 taggtttatg ggggtggaga atgggtagat ataacacaca cccagcgcaa ggcggaggtc
    18301 attatcatga cattaaattg tataagcacc gtggcagatc tttggaacag ttccaagaac
    18361 aaaagctact gaagaagtta aaaaaaaacg caaaaagggg cgatagtatg acaatttatg
    18421 aggctagagg tttccagagt aatcttgtct atccatttga taagatggag ccgttccagt
    18481 acattgaacg ctttaagcct ttggtagtcc ctgaaagtgc tgatccggag gaatacaaaa
    18541 gaactcaggc gccatattgt ttaagtggta aggttatgcc ggagaaaaac gggagttaca
    18601 aacgaaacaa ctccagtcta atctatcggg atttgatttt ccttgattat gacgatatac
    18661 aggggacgac tgaggacttc atagaagccg tttctagcgc tttgtttggc tactcttata
    18721 tcttataccc gactatcaaa catagcatag aaaagccccg ttttcgcctt gtggtgaaat
    18781 ctaacaacgt gatgaacgag gcaacctata agcaggtagt aaaagagatt gctgacaaga
    18841 ttgggctacc ctttgacatg gccagtttaa cctggtcaca actccaaggg ctaccagtaa
    18901 caacaggcga cccagcaact tatcaaaaga ttgtagagca tggacttgat tatccagtcc
    18961 ccaaggttga accaagagcg aagcaaggaa ctactgagcg ttataaacct agagtaagtg
    19021 gccagaggtc aatgactatg aggatcattg acacgctttt caacggattt ggagacgagg
    19081 gagggcgtaa cgtggcagtg acacgctttg tgggattact cttcaataag tgggttgatt
    19141 gtgacctaga gaccgcctat gaactgacaa agatagccaa tagtgtgaca gttgaaccat
    19201 tgcctattga agagctagac cgcactttta gcagtatagc acgggctgag tatagaaaga
    19261 gaggttagaa ccatagaact agaagaatta gcaaacctaa aaagtgaaat catggaggta
    19321 atggagcaag aacaccctcc tagaacgatg aaggagcttg aaaatcgtat ctttaaagct
    19381 ggagaagaat ggcgggcaga acatactgaa actaaggtaa atgagaccac aggggacgtt
    19441 accgaaaagg ttgccatgcc tcagacattc acagtagcaa aaatactgag cgagattgtc
    19501 acatttactt ttatcagcaa gagcaatata cctgattata gcctgctcta tatctatgat
    19561 ttagacgagg gtatctatac cgctagtaat gatctattca atcttttgtg taagaccttt
    19621 gacgttagaa ttaaacccag agagtggcca cagattaagt taatggttag aacattggca
    19681 aagatacgaa aacctttaga gagtgctaac cttgtacctg taaagaatgg cattattgac
    19741 ctaagaacta aggagctact cccctttagt cctaagtatg taattacaag taagataagc
    19801 acggcctacc acgcgcctaa acgagtccca acagatagag agggcaaaac ttttgatgat
    19861 tggctaaact caatcgcttg taatgatagt gaactggtaa cactgttttg gcagattatc
    19921 cttgaagcta ttaaccctaa ccatacccga aataagtttg ctatcttcta cggggacggt
    19981 aacaatggta aagggacatt ccagcgcttc cttatcaatc tgatagggga aagtaatata
    20041 tcagccttga agcctgcaca gttcggagaa aagcataact tggagacctt ggtaggtaag
    20101 gtttgtaata ttggggatga agcgcctaac gaatatttaa aaaatccgtc tgatttaatg
    20161 agtatcacta gtggcgacac tgttctagtc aatccaaaag gacgcccagc ctttgaagct
    20221 actttcaagc tattcaatat cttttcaggg aattatattc ccaatggtgg caacaagaca
    20281 aaaggctggt atcgtagaat tatgatcgtc ccttttaatg ctgactttaa cggggagaag
    20341 gaaaaacctt ggattaaaaa tgagttttta gcaaacaagg aagtcctaga gtatgccctc
    20401 tacaaagcta tcaatcaaga gccatttact cactttatcg aacctaaagc agttaaagga
    20461 ctcctagaag aataccagga ggataatgac tacttacttt catgggttaa gcatgaatac
    20521 atggaaaaag gttgacatga gctggacgta gtacctgttt ttatcgttac aagatcacta
    20581 aagcactatg ccgaagatat gggaataccc aaacccaatg tttacggggc tggtaaagaa
    20641 actatcaagc acttacaaca gttgacacct aatcggtatt ctctaagaaa gaaaagagtt
    20701 ccttcagaag attttgaaaa actagaggca tgggacgttg acaagataaa aatgcggaca
    20761 cctcaacact ctatcactaa acaagaataa gtgtgacgtt ctttttttgc ttaaaccctt
    20821 gataatactg attttcttaa aaaaagtgtg acgttgtgac attctttcca actcttacat
    20881 atagagaaaa atgcagtatt tatatatagg aacgataaaa caaaagaacg tcacagggtc
    20941 acaggggtgg tgaaacacct agagcctcaa gggtttgaac gtgtgacgtt ctttgtcaca
    21001 gaaggtcaca gaacacgaaa aatattacat aatttacctt aaaataaaga aatgacaaca
    21061 acatgaaagt taaactattt gaatatacta gacgatggga aaaagaagac tttgagaaag
    21121 agatcaatga cttcatggca actgttgaag tgctggacgt taaattttct ggtacaccat
    21181 ctagtgaatc ctttaattcg gtggctatcg tattggtatt atacagataa caaaatgggg
    21241 tagatagtac cgaccccctt gtaatggtgt aactactagt gacaccttta aaacagaaag
    21301 aggaaaaaca acatgacatt aaaaacattt tcggataaag ccaaaacatt tactttcact
    21361 tacgaattta aagacctaga tactgctatg gtagcaggtc acgcgctact gggatatatg
    21421 actgggactt atgaagtacc atctatttca ataactcaca aggataaagg gacgcttgtc
    21481 gctgagtatg tggaagatca caagctaaac aagactttca agcgtatttg tgacagtttc
    21541 aaagactatt acaaccaacc agtggacgat gaagcatttg aagaacgtta taaacgggag
    21601 cgcgtgctcc aactcaaaga gtcagaggac tttgagaact tgctggaaaa agtaacagac
    21661 tacgagctgg aactattaga ctatgctgat cgcttgcttt ctgataagcc tatccctatg
    21721 gactctatga ccgcttttgg tacgttggaa atgctgggcg atgaaagtat tagcctactc
    21781 caaaagttgg acgtagaggt cgaatataaa ggccttgctg gttatacaga gcatttgaag
    21841 tagaacacag gggagcaatc ccctttttgt tatcaagtca atagttttgg gtttttccat
    21901 atagggggaa ataatgaagc ggttagcaat agaaacaatc actaaaccaa tgaagctgag
    21961 aggaatatct aagggtatag ctgagttgga cggtcaacgt ttagagattg atttggataa
    22021 tttaatgatt gattttggtg gagagtcatt tgaattagac agaatagcag gaactaaggg
    22081 aggtaataga tatttctttc tttgccctga ttgtgggaga cggtgcaggt tgctttataa
    22141 acggtattta tattttagtt gcggtacttg tctagatatc cacaagagca ccctgaaccg
    22201 tagtaaaacg gattgccaat actactggga gcttgcacta aaagaagcca gaaaggtaga
    22261 accagggtgg agtcctagac gtggtggata tatgtttgat agtttccctg aaagaccaaa
    22321 gtatatgaag cgtgacaggt atcataagca ctataagaag tttttgaagt atattgaaaa
    22381 aggagataga ttttggctga atggtttgag attgtaggac aatatgaagt agtgtgcaat
    22441 ttacaaaaca aacaaatact acatatttga cggtttgaat gttaaaaaag ctagatatat
    22501 caaggattta agtaagtaga gtgttccaaa agagggtgag gtaagggtga ggttacatat
    22561 aaaaagtaca aggttagtac aaggtcacat acttcaaaat agcaaggttt tagcaaggta
    22621 cagggctttt ttctagtgat agaaccctaa tattacccta aggtatagct acttttttag
    22681 aaccatagaa cggtaaggtt acggtaaggt atcgaagttt tccaatggtg aggtaagggt
    22741 gaggtaagag caaaaaatgt aaaggttttg tcaaggttgc gtatttaaaa gccccaaggt
    22801 taccacaagg tagagaggtt taccgagggt tagaaaaggt gagattttgc ttaggtagtg
    22861 gcagtaaata tgcctggaaa atggcagggt tatgtgtgtt gaactccgag cgaacgccga
    22921 gaaagtggct atatctccct ccccacgcac ttctatgagc ttcacaccgt cattgtacat
    22981 tttttctcac ggggaagcat ttgaagctag agcgaacata gagaaaacga aaaaagccaa
    23041 gacactctct gtctcagcta atagttctca caaagactat tatatcatag aggaggccga
    23101 ggcatgacac cagagcaggt aaaagaaaaa ctagagggcg ttaagtggat aaacaaagag
    23161 atagaaggct tatatttaga gcttgcagct ttagaaagtg gtattatcaa aaagcaagaa
    23221 ctaagcaata ccagagtaca aacaagcagg gtaaatacga ccgagaataa ccctataagt
    23281 gttctaaaac taaaagagga tacacttcag agaattgagc gacttaatga agagagaatg
    23341 gaaatatcta ggctaatcga taagctagcc aatccgcttg aacgttctgt tctcaggctg
    23401 ttctacttga atgttcttga cgcttggcaa gttgctgagg aaatagataa atcaaagact
    23461 gcagtataca ttataaggca aaaagccata gaacacttag caaatgtggg gtaataggtg
    23521 agcacaaaaa aacgcctaga acaatctaag cgctaaagag tagtggacgg tgtgcctgtc
    23581 ccgtcatctc atactatgaa gttgcgtagc gacactatca tctctacctc acttctcttt
    23641 agactattat accacaaagg agcgaactaa tggagctgga taagtttaaa acgatgatga
    23701 acgtcagaga gcggatgacc tactttctac gtttccagag gatggcagga agtgaaaacc
    23761 aagttacgat agatgaagag gcttggaaac ttgtcttacc ttatcggtgg gatttgagcg
    23821 gtgagcatga aaaagcaatc cgtgaggggt tggaaatatt cgcccaagac atcaacagta
    23881 tagaaaacaa acgagctaga aaatacttta ttatccatta ctgttacatg agaaagaaaa
    23941 caatgagcga atgcgtagaa atggcagcta ctagctccac tagctaccac cgatataaac
    24001 aaatagccgt cttaaatttt gcgagaatcc accagaacgg agagctagaa gtgtataagt
    24061 aggcgtttgt ggtgttttgt tgagaaatgt tgagatttaa gtgagggggg atgacatgat
    24121 tgaagatttt ttgattgatt tggagaatat ccaattagag gatatggaga tagattttaa
    24181 catggatata gacatcgatt taaacataga ttttgaaata gatgttgacc ttgatgattt
    24241 agatttaacc ttactacaag aattagaagc gtaaatgttg gcaaatgtag gctgaggctt
    24301 catattcgtc ccctattttg ctttggtttg gactggacaa ttaaaacacc atggataaac
    24361 tagaagccct cagaaacgag tctaggggct tttgtgaggt cataatctta taaaccacgc
    24421 gcttcatggt ataatatacc tatcagcaac cagcaataaa aaaagcacgt ttaaccgtgc
    24481 tagtttcttg cctgctgaac tcgtcattta ttgccctttt gtggggcttt ttttgtggac
    24541 tttttgagaa tttttaagaa cttttaatga tttctaatca aatgagattt ttcaaaaagt
    24601 cagtaatatc aagggtttag gcgctttaaa caagtttaaa agcgtataga ttacaatcta
    24661 acacaaaaag ggataaagtg ctaaccctct aactaagggt tctcagtcaa taattttatt
    24721 catttttcgc tcaaaatcat atcgccccat catgacaaca tgctcacaat tactgcattt
    24781 tattttgata tctgctccta cacgtgtaat ttcccaacga ttagcctttt taccagtcga
    24841 cttgattgta caagcgtgtg attttttcat ctcaacaaaa tttccaactt gatacatact
    24901 actctccttt tctttttcga ttatatcata aaagaggcga gccaggctca acctctttca
    24961 cttaatttgt acgaactggt gtaatgagct gcatgaagtc ttcgttagta tctgctggca
    25021 caagagtaaa tggacgaaca gctgagataa agctaatggt caccttttcg ctatttaaag
    25081 ctttaagaga atcaatcaag taagttgggt tgaaactaat ggtcaaatct tcaccagtaa
    25141 cctgatcagt atcgatttct tcgtttactt taccaacttc tggagagtga acatgggcgc
    25201 taacaacccc atccttaatt tcaagtttca cagtaccatt ttgagtcgca cttgataaaa
    25261 gacgggcacg ctccattgac tggcgtaagt ttaccacatt aaaagtaata gtagtgttaa
    25321 agtctgttgg aatcaagcga tctgtatcag gatagtttcc ttctaggaga cgagtataga
    25381 agctaatatt ttcgcttcta aagaggattt ggttattggc aaagaaaatc tctacagttt
    25441 cgatatcatc tgtaaatacc gctgaaaatt cgcgtagaga acggctagga attacgacat
    25501 caaaatcatc actatttttt tcaagagtca attttttctg gcttaggcga tgagagtctg
    25561 ttgcaactgt ttttaactct ttgtgttgac tcaatacgaa gtggacacct gttaaaatcg
    25621 gacgactctc ttgtgtactt gcagcaaagg ctgtttcatt aataattttc ttgagtaatt
    25681 ttgtttcaag tattaaagga gtgcttgctg aaatttcttg gattcgtgga tattgttcgc
    25741 tatcttttcc ttttagggta atttctgatt tgccactggt taaaacaatt tgattttgtt
    25801 caatttcttt aaaatcaaga gttacatcag gtaaactaga tactacattg ataaagaaag
    25861 aagcttcaag aaggatcgaa cctaaagaag taattaacaa accagcatct tcattttttt
    25921 gagaaataaa attttcaatt gaaatttgac catttgaacc aattaaagta ataccttcat
    25981 tggtcacgtc aatttttact gttgataaaa taggaatggc atttttagaa ctaatagctc
    26041 tcttagtagt atttaatgct tgtagaaata aatttttatt aattgaaaaa tgaatcatgg
    26101 attctccttt atttattttt agtattagaa agataatagt aataatagag tctgtgaaat
    26161 ctgtggaaaa cagcctttaa acaagtcata tcaagttttt tagcttgttt aaaaaatgtg
    26221 gataaaaaag ataaaaaact aaaagttatc cacaaattat ttgattttct ttttgattga
    26281 ttcaatttct aaacgtaaat tatcgtcttg atcaatcaaa gattttattt tggcatgggc
    26341 atgaatgact gtggtatgat cttttccccc aaattccttc ccaatttttg gaagactatt
    26401 atctgttagt tctctagata aatacatggc tacttgacgg gccaaaacaa tattttgaag
    26461 gcgtctactt cccttcattt ctttgatact aacaccataa aagttaccaa cttcagtttg
    26521 gattttatca attgggatga cgagcatttg gctaacatct tgtttgcggg ctctaatggc
    26581 ttctgcagca atatcaatag tgatatcctt gatttttttt actctggcaa ttaaagtgat
    26641 gtcgttgatg gctccctcaa gatctcgaac atttgaatca aattgcccag ctaggtattc
    26701 tagagtatca ctttggaaat tgtagcctaa atgttccgtt ttactttgta aaatggcaat
    26761 acgtgtttca aagtcagggg gtgtgatagt ttgtgtcaat ccccaactaa aacgcgtgac
    26821 aagcctctcc tcgagccctt ctagatgttt tggactacga tcactcgtta ggacaatctg
    26881 tttttgcttg tcatgaaggg cgttaaaggt attgaaaaat tcttcctgag ttgcaacttt
    26941 ttttccgctg agtgactgga tatcatcgat taacaaaaga tcaagactac gataggtctt
    27001 tttaaacttt tccatttccc caagtcttag gtgatcaaga aagtcattaa taaagctttc
    27061 ggcagggata tatttaacac gcgcattagg aatatttttt agaatttcat ttccaatagc
    27121 gtttaataag tgagtcttac caaggcctgg tcctccatag ataaaaagag ggttataggt
    27181 cagagccaaa tcttcagaga cagctaaagc ggctgacaca gcccaaacat ttccatcccc
    27241 ttgaataaag ttatcaaagg tatacttttc ttttaatccc gtatctgaat aaggaataga
    27301 tactaacttt ggactatagt tataaagagt taaatttgta gcttcttcaa cttgtgagct
    27361 agtcgtatct tgaggtttgg tgaaaatata gtggggagtt atttcagcgt cataaatttc
    27421 aaaaccagct actacaataa tatcttttag ttgtttttcc cagaccattt ccatttcaga
    27481 gcgaggtaga aatatagtgg caacattttc ctctaccttg atgagttcag cttgaatagc
    27541 atagaaatca tacatggatc gagtcagtct ttcttgtgca aattctaata tacgattcca
    27601 aaattgtttt tctttcaatc ctttctcctc ctttactatt taaaagttta atactagaga
    27661 tattttacca tagatagcaa gaattttcca caagctgtga aaaataatcc acaatgttac
    27721 taaactttat ccacaggttg gggataaaag aagaaattat tgatttatta agctttttat
    27781 cgaaaaacat agtggataac cttgtgagat aaaaaaataa aagaacagcc ttatttcagg
    27841 ctgttgataa ttctactata ttcttcttga tttgaaaaat aaataatgat ttttccactg
    27901 tcttttttag atagtttaat ttctacatct aatccgagta gttttcttaa ctgtttttct
    27961 tcattttgta tgaaataatt agttttttgc tgtttctttt gttttttctc tgtcagaaga
    28021 gcttctaact tccttacaga aatatcttct tctataatcc gttgaaagaa atagtcttgt
    28081 tgttccttat ttaacccaac tagggaacgc gcatgggctt gtgatagttt gccattttct
    28141 acttctgaga gaatctgttc tggcaaggaa agtaaacgaa tggagttgct gatatatgga
    28201 cgagacttgc ccatcttatc tgcaatttca gcatgggtga atcctttctc tacgagagat
    28261 tcataggcgc gtgcttcttc tattgggttt aaattttctc tctgtaaatt ttcaataatg
    28321 gactggacca tcatctcttg gtctgaaatc tgtttaacaa cagctgggat agaccgtaga
    28381 ccagctaaaa gtgaagcccg atagcgtctc tctcctgcaa ggatttcata accaataaca
    28441 ggagattgac gaacaataat cggttgaatg accccatttt ctttgataga ctgtgctagt
    28501 tcatctagtt tttctctatc aaattctttt cggggttgat agggattttt ttgtatatct
    28561 gtgatagaaa tcatttcaaa tttttccatg attctacact aacacatctt ttctcttatg
    28621 taaagctttc tttacataga tgtcaattaa gattctaaat cacctgaact cttgttaagt
    28681 ttgatagagg tagtttcttc tttcccgtta cgatagtagg ttatcttaat ggtgtctccg
    28741 atagaatggt tgtaaagagc actttgtaag tctgttgatg aagcaatctc tttgtcatct
    28801 acttttgtaa ttacatcgta tttttcaagg tgaccattgg caggcatatt actttgtacc
    28861 gaacgaacaa ttacaccaga tgtaacatta cttggaatat tgagtcttct gatgtcgctt
    28921 gtactcacat tagataaatt aaccatctgg attcccaaag ctggacgcgt cacttttccg
    28981 tttttttcta actgttcaat aatattgata gcatcatttg caggaattgc gaaaccaaga
    29041 ccttctacag atgttcctcc atttgtagca attttacttg aggtaattcc gataacctgc
    29101 ccttgaatat tgatcagtgg gccgccagag ttacctgggt taatagcagt atcagtttgg
    29161 atggcttttg tagaaatagc ttgtccatct tccgatttta aggatacatt tctattgaga
    29221 ctggatacga taccttgagt gacagtattt gcatattcag aacctaacgg gctaccgatg
    29281 gcaatagcag tttctcctac agttaactta ctagaatcac caaactcagc tactgttgtc
    29341 actttttctg aagagatttt gacgacagca atatcagaga aagtgtcagc tccgacaatt
    29401 tctccaggta ctttagtccc atctgacaat cgaatatcta ctttgctggc gccatttata
    29461 acgtgattgt tggtgacgat gtaagcttct ttatcattct ttttataaat aactccagat
    29521 ccttcactag agattcgctg agaatctgtg tcagtatcat cattgccaaa tacgctattt
    29581 tgtctgtttg ccgaataagt aataacagaa acaacagcat cttttacttt gttaacagcc
    29641 tgtgttgttg aattttcgtt cttataggca gtttgtgtaa tagtactatt gttgttagag
    29701 ttgtttacac tacttttttg agttagttga gttattgaaa aactacccaa ggctccacta
    29761 aaaaagctaa tgacgataac gactaataat tgaaaccatt ttttgtaaaa tgtttttaga
    29821 tgtttcatat ttgcctccat atgtttgaat tactgaaagt ataaactgac tagcttaatt
    29881 ataacttaaa cacaaaagtt ttacacaaac tgtggataac tcttttgaaa ctgtgatttt
    29941 cttaattgaa atctattttt tattttgtga ataagatgtg aaaaaataga gaatatgtta
    30001 gaatagagtc atgaaaatta aagttgtaac agttgggaaa ctgaaagaaa agtatttaaa
    30061 agatggtatc gcagagtatt caaaacgaat ttctagattt gctaagtttg aaatgattga
    30121 gttatcagat gaaaaaacac cagataaggc cagtgaatca gaaaatcaaa agattttaga
    30181 aatagaaggt cagagaattt tatcaaaaat tgctgaccgt gatttcgtta ttgtgttagc
    30241 cattgaaggg aaaactttct tctcagaaga atttagtaag cagttagaag aaacttctat
    30301 aaaaggattt tctactctta cttttattat tgggggaagt ttaggattat catcatctgt
    30361 aaaaaataga gccaatcttt ctgtcagttt tggtcgccta accttacccc atcagttaat
    30421 gagactagtt cttgttgaac aaatctatcg cgcttttacg attcagcagg gattccccta
    30481 ccataaatag aaaattgact tttaattgaa tttttggtag aataattgta ttaggtctca
    30541 tagctcagct ggatagagca ttcgccttct aagcgaacgg tcgcaggttc gaatcctgct
    30601 gggatcaata taatagcaaa gctgggaatt ttcccggctt ttttcttaaa aaagtacact
    30661 ttgggagaaa aaaatgacag ttgagagaat tttatctaaa acgaaattcc attttgtata
    30721 atggtttttg taagttagct tacaagaaaa aacattttag gagattttat tatgaaaaac
    30781 acagttaaat tggaacagtt tgtagctttg aaggaaaaag acttacaaaa gattaaaggt
    30841 ggggagatga ggatttcaag aatcatcctt gattttcttt tcctacgaaa aaagtaatga
    30901 aataaggaga aagagtaatg gatttacttg gatttgggac agttattgtt cattttttaa
    30961 ttattagtca cagttaccgt ttaatttgta aaggtcgaat aaatagaaaa gaattatacg
    31021 tttttggtgc ttatacatta ctaactgaaa tagtacttga attttccttt tatcttctat
    31081 atttagataa aatagggatt gaaagatttt tatttccttt gggcttatat tcctattttc
    31141 gatggatgaa acagtatgag agggatagag gactattcct aagtttacta ctatctcttt
    31201 tatatgagag cactcataac tttctgtccg taattttctc ctctataaca ggagataatt
    31261 ttgttttaca atatcatttc ccattctttt tcgttgtgac ggtgttaacc tattttgtta
    31321 cattaaaaat catttactat ttccatttgg aactagccta ttttgacaag gactaccttt
    31381 atcctttctt gaaaaaagta ttttttgctt tactattgct acatattgta tctttcgttt
    31441 cagatatggt aagtacgatt aaacatttga atagttttgg aagtattttg tcatctattg
    31501 tctttatctc tctccttttg accttctttg caatgaattc tcataaagtt caaatggaga
    31561 aagagattgc tttgaagcag aagaaatttg aacagaaaca tttacagaat tacacagatg
    31621 aaattgttgg tctgtataat gaaatccgtg gttttcgaca tgattatgct ggaatgcttg
    31681 tcagcatgca gatggcaatt gacagtggta atttacagga aattgacaga atttacaatg
    31741 aagttttagt caaagcaaat cataaattgc gttcagataa gtacacttac tttgatttga
    31801 acaacataga agactcagct ttacgaagtt tggttgctca gtcaattgtc tatgctcgaa
    31861 ataatggtgt agagtttaca ctggaagtaa aagatacgat taccaagctt ccaattgaac
    31921 tattggattt ggttcgtatc atgagcgttt tattgaataa tgctgtcgaa ggatcggctg
    31981 atagctataa aaagcagatg gaagtagcag ttattaagat ggaaactgaa acagttattg
    32041 tgattcagaa ttcatgtaaa atgacgataa ctccttcagg agatctattt gccttaggat
    32101 tctccactaa gggaagaaat cgcggagtcg gattaaataa tgtgaaagaa ctactagata
    32161 agtataacaa tattatttta gaaacagaga tggaaggcag tacatttaga caaatcatta
    32221 gatttaagag ggaatttgaa tgaaagtttt aattttagaa gatgttattg aacatcaagt
    32281 gagactagag agaatattgg atgaaatttc gaaagaatcg aatattccaa tatcatacaa
    32341 gacaacggga aaagtccgtg aatttgaaga atacattgaa aatgatgaag taaatcagct
    32401 ttatttccta gatatcgata ttcatggaat tgagaaaaag ggatttgaag tggctcagct
    32461 cattcgtcat tacaatcctt acgctattat cgtctttatc actagtcgat cagagtttgc
    32521 gactctaacc tataaatacc aggtatcagc cctagatttt gttgataagg atatcaatga
    32581 tgagatgttt aagaagagaa ttgagcaaaa tatcttctac acgaagagta tgttacttga
    32641 aaatgaagat gttgtagatt atttcgacta caattacaag ggaaatgatt taaaaattcc
    32701 ttaccatgat attttgtata ttgaaacaac aggggtatct cataaattgc gcattattgg
    32761 taagaatttt gcaaaagagt tttatggtac catgacagat attcaggaaa aggacaaaca
    32821 tactcagcga ttttattctc ctcacaagtc atttttggta aatataggca atatcagaga
    32881 aattgatcga aaaaacttag aaattgtttt ctatgaagac catcgttgtc ctatttcaag
    32941 attaaaaatt agaaaattaa aagatatttt agagaaaaaa tctcaaaagt gattgacaat
    33001 tagcaagaaa ttgatataat ggttatatct gctacagata gaaggtccgt tggtcaaggg
    33061 gttaagacac cgccttttca cggcggtaac acgggttcga atcccgtacg gactatttta
    33121 tccgccatag ctcagttggt agtagcgcat gactgttaat catgatgtcg taggttcgag
    33181 tcctactggc ggagtataga taaaagggaa cacagctgtg ttcctctttt tgtatcaatt
    33241 tgtatcacca agcattttca taaggaagtc tgttatttct tgagaacttt ctttttttcc
    33301 atgtgcaatc caagtttggc agacaccaaa aagtgcatga gttagataga tgctactata
    33361 ttctaattca gtggtattta gattcagttg cataaatcgc ttttgtaaat ctgtactgag
    33421 catgatatga agtttatttc gtaagaaatt ttggatttct ttagtcccat tttcagaaag
    33481 aagggcagcc agaagtggtt ctgactctag atattcaaaa acttctaaaa tagcgtctct
    33541 tttgtgatga gcatgttttt gaaaaatata ttcaaatgta tggaatagct tgctttgata
    33601 gtgctcaatc atatcatact tatccttata gtgagtatag aagctggaac gactaattcc
    33661 ggctttttct actaatttga cagtagaaat tttatcaaat ggctgttcca tcagtaattg
    33721 taccatagcg ttttcaatag ttcgctttgt ttttaagcgt ttgttacttt cttgcatatt
    33781 tcctccttgt aaacaaatta gactatatgt ctaaaaatag attttttatc ttgtaattta
    33841 gattttttaa tgtataatct attatatcaa aattttagac aatatgttta aaaaaggaga
    33901 aactatgttt aaagaatgga aagcaattta aaaaaaacca acctttatta ttgtcatgat
    33961 cgggatttct cttattccag ctctgtacaa tatcatattt ttgtcatcaa tgtgggagcc
    34021 atatgggcaa ttgtctgact tacctgtggc agttgtaaat aatgataaag aggcttccta
    34081 taatggtaat actatggcaa taggaaaaga catggtgtcc aatttaaaag aaaataaaac
    34141 cttggatttt cattttgtag atgaagagga aggaaagaag ggattggaag atggcgatta
    34201 ctatatggta gtgactttac caagtgattt atctgaaaaa acaactacat tatccaatat
    34261 tcaatcgaca gcagcttatc aatcattgac aagtgagcaa caaactgaga taagtgattc
    34321 tgtatctcaa aattcaactg atagtattca atcggctcag tcaattgtag ctttagtaca
    34381 aggtttacag ggaagtttag aaaacttaca aaatcaatct tctaatcttt cgactttaaa
    34441 aaatcaagct aatcaagtat tacctattac ttctacttct ttgataggat tgtcaagtgg
    34501 attaacagag atacaaggag ctgttactag caaattagtt cctgccagtc agtcgattgc
    34561 atcaggtgta aacgcatata ctacaggtgt tgataaagtt tctcagggcg caagtcaact
    34621 aagtgaaaaa aatgccacct tgacaggtag tttggatcaa ctagtttcag gctcaaacac
    34681 cttgacacaa aaatcttcta gattgacagc aggagttgat aaattacaat cagaatctgg
    34741 gcaattagca gacaaatcca gtcagttact ttcaggtgct tctccattag agaatggagc
    34801 taataaattg gcagatggat ctaggaaact agcagaaggt ggaacaaagt taacttctgg
    34861 attggaagat atacagacag gacttgataa tgctagtgat caactcaaat cagcatcaac
    34921 agaatctaaa aatgcagaga ttttgccaaa tccactcaat ctttcaaaaa cagacaatga
    34981 tcaagttcct gtaaatggaa tcgcaatggc tccttatatg atatcagttg ctctttttgt
    35041 tgcagcaata tcaacaaata tgatattttc gaaattgcct tcaggacgtc atccagagag
    35101 ccgttgggct tggttgaaat ctcgagctga aataaatggt attatagctg ttttggcagg
    35161 aattttggta tatggaggag ttcatcttat tggtttaact gctaatcatg agatgagaat
    35221 atttattctc atcatcctaa caagtttagt attcatgtct atggtgacca ctttaacaac
    35281 gtggaatagc cgtataggag ctttcttctc acttattttg cttttactac agttagcatc
    35341 aagtgcaggt acttatccac ttgctttgac aaatgatttc tttagatcta ttaatccctg
    35401 gttaccaatg agctattcag tttcgggatt acgacaaaca atctccatca acaagtcatt
    35461 ttcctagctg tcatactagc tctatttact ggtttaggta tgctagccta tcaacataag
    35521 aaaatggaag aagattaaaa aaatcgaccg attaactggt cgatttttta tgccttagat
    35581 gactttcgtc tgtgattata gattccaaat agtaagagag aagtaaagga acagattgct
    35641 ccagtaataa aaccattggg aatgaaggaa agtgtaatag ttcctttccc cttgggaatg
    35701 tcaactttca taaatccagt ttgagcttgt ttaatttcta ttttcttacc atcttggtag
    35761 gcagaccaac ctttgtcata aggaatggtg aagaaaatag atgtatcttg ttggacatca
    35821 tatgtagcaa aaaccttgtt tttagaagtt gatactgtga taggttgttc tttaattttt
    35881 tgaattgcct cggtgaaagt tttggtatct aaacgataga aggtaggaga ttcaaatgat
    35941 acttgtgaat ttccagggaa actaacattg atattgaaag tttttttctc tttagtatat
    36001 cctagattaa agaaggagaa gacattatca gttgtaaaag tctttttttc accatttaca
    36061 aggatgtcaa ccttcttttg tttatcgtta gaaaagtgaa ggtttatgaa agagagataa
    36121 acttggctgt tttctggaac ttcaatttga tactggattg ctgcatcttc atttgaagaa
    36181 cttgtgacac taatcaaatc attagtattt tctatttttt ctgttttttc ataaggtatt
    36241 ggagaaaaat aatcaaaatt gacgttagca agttgattta aaaatgaggc ctgattatcc
    36301 aaggtatgtt cattgaactt gacatcattg taaacagatt gactagcaac tgcaatcgga
    36361 agagagtatt gattttcata tagggtaaga ttatcttttt gatagatatc tttaaagcca
    36421 tacttatcaa taggactgtc tgagatattg tactggatac caaataaact atcagccaaa
    36481 atactattat ttgcatatcg gagattgaga ttagtcccag aggatttaaa accaagttta
    36541 tctaaagtag agcttgatga acgatttcga acagatgaaa attgagagat tccattgtag
    36601 ttgaatttca tactgtcatt tcctgtctga gtttgtagtt tttcagtacg agtaaattga
    36661 tttccaatat atgttgagaa agattccata gctgggatat ctcgactata agcacttcga
    36721 gaagcaaatc cccattcctt agcaattccg tccatttgag atgaagcatt taaactcatt
    36781 tcaaccagta taaataaaga gattagaatg gcaaatagat tcacagatat aaactttttg
    36841 ataactgcaa ggagtaaaag agaatagaca accaaaaatt caagagtaag cagaatattc
    36901 aaatctgtta aaaaagaata atgcgatttt agatagatgg tagctaaaaa tcctgttact
    36961 acaagaaaaa gcgaaactaa aaaattccag actttaagtt ctttcagacg ctttaagact
    37021 tctgctgctg tgtaaattaa caaggtagag aaaatccaag catagcgatg taaaaacatg
    37081 tttggagtat gcatgccttg ccaaaataag tcaagagctt ctatgtaaaa gcttgcaatt
    37141 agaaatgcaa agaatattac atatatgagt ttcacgtgaa acttaataga tttcagcgta
    37201 aaaaataaaa tggtcaaaat aaagggaagt agtccaacaa aaatcattgg gatggcccca
    37261 tactttgttg tgtcaaagga accaatgaat tgcttagcaa agagatcaag ataccagcta
    37321 ctttcagttt gaaactttgt aacttcagtc aatttttccc catgtgtctg taaatcaaac
    37381 agagtgggaa gaatcataat caaactagcc ataccggcta aaaaggagat aactataaaa
    37441 tcaagaacag atgattttcg agtcttaaag tcccacgaaa tttgacagag ataccagaaa
    37501 ataagaaaca atactgtcat atatccaaaa taataatttt gaataaataa gattgacaga
    37561 cttgtaaagt acaataggag tttcttttca gttatcagta gatgtaaacc agttataatt
    37621 aaaggaatca agataaaaac atctagccag gtttttatct ctaattgact gacagtgaaa
    37681 ctcatcagag cataggaagt agataaggct agttttaaag tctgagggat agattgaaac
    37741 aatttattca aactaaaaaa ggttgacaga ccaatcaatc caaattttaa gagagttgtc
    37801 agatagatag catctggcat attcgttaga tcaaaaaagt aaactagagg cgcgagaaaa
    37861 ctacccaagt aataactaga tagggcatag aagtttagcc ctagaccact tgtaaaggtg
    37921 taaaacagac tactatttcc atgtaggata tttcgtaagg ctacatcaaa aataacgtat
    37981 tgatgaaagc catctcctaa tagaggagag ttgtcgctat tccagtagat accttgagat
    38041 agatatactc tagacataat cactacagga atgatgaaag aaataaaata ggttcgatat
    38101 gtttttaaaa atgatttcat gttacctcgt agaatgatag aaaactcagt tggttaaccc
    38161 aactgagttt tgaagtttta tttagtcttt ccaaagttct ttaacttttg cttgtacttc
    38221 tgcattttct aggaattcat cgtaggtttc atcgatacgg tcaatgacgc catttttaga
    38281 taagacaatg atatggttag ccaaagtttg aataaactcg tggtcatggc tggcaaagat
    38341 gattgattct ttaaagtttt tcaatccatc attcaagctt gagatagatt ccaagtccaa
    38401 gtgatttgtt ggatcatcaa gtacaaggac atttgatttt aagagcatga gttttgaaag
    38461 catgacacga actttttctc cccctgacaa gacatttaca ggtttgttaa cttcatctcc
    38521 agagaagagc atacggccga ggaagccacg taggaaagta ttgtcatctt cttctttact
    38581 tgcgaattga cgcaaccagt caagaattga ttctcctcct gcaaaatcag ctgagttatc
    38641 ttttggtagg taagattgac tagttgtaac tccccacttg acagttcctt catagtcaat
    38701 atctcccatg attgcacgaa ttaatgcagt cgtttgaata tcattttgtc caataagtgc
    38761 tgtcttatca tctggacgca agatgaaact aatattatcc aagatagttt caccatcaat
    38821 ctttacagtt agattttcta ctgtcaagag atcattacca atctcacgtt ccgctttaaa
    38881 gttgataaat ggatatttac gactagatgg tacaatctct tctagctcaa tcttatcaag
    38941 cattttctta cgtgatgtgg cctgccttga cttagaagca ttggcagaga aacgagcaac
    39001 gaattcttgc aattgtttaa ttttttcttc tgctttagca ttacggtctg ctagcaattt
    39061 agcagcaagc tcagaagatt ctttccagaa gtcgtagttt ccgacataga gtttgatttt
    39121 tccaaagtca aggtcggcca tgtgagtaca aactttgttt aagaagtgac ggtcgtggga
    39181 tactacgata actgtgttat caaagtcaat caagaagtct tctaaccaag taatcgattg
    39241 gatatccaaa ccgttagtag gctcgtccaa gagaagaaca tctggtttac caaaaagtgc
    39301 tttggcgagg agaaccttta ctttttcacc gttggccaat tcgcttatgt tttggtagtg
    39361 taattcttct ggaatgttta ggttttgaag tagttgagag gcttcactct ctgcttccca
    39421 acctccaagt tcggcaaact ctccttcgag ttcggcagca cgaaccccgt cctcgtctga
    39481 gaaatcttcc ttcatgtaga tagcatcttt ctctttcatg atgctataaa gtttttcatt
    39541 tcccatgata acgacatcaa tggcacgttc atcttcgtag tcaaagtgat tttgacgaag
    39601 aacagagaga cgttcatctg gaccaagaga gatgtgacca gtagtaggtt cgatatctcc
    39661 agctaaaatt tttaaaaagg ttgattttcc ggcaccatta gcaccgatta atccgtaagt
    39721 atttccttct gtaaatttga tattgacatc atcaaaaagt ttgcgatcac taaaacgtag
    39781 tgaaacatca gatactgtaa gcaatatttt tctcctatat gtgtaatata tttattctac
    39841 tagaaaatac agaaatattc aaatttttat ttgtcaattt tgtgtaaatt atatttacag
    39901 tatcctttac acaaatctgt aaaaagcaag gctgatttat tttgataaat tacggttatt
    39961 tcattaaaaa aatgctataa ttgaaaggac tatatcgaag gagaacaaaa tgactaaacc
    40021 cattatttta acaggagacc gtccaacagg aaaattgcat attggacatt atgttggaag
    40081 tctcaaaaat cgagtattat tacaggaaga ggataagtat gatatgtttg tgttcttggc
    40141 tgaccaacaa gccttgacag atcatgccaa agatcctcaa accattgtag agtctatcgg
    40201 aaatgtggct ttggattatc ttgcagttgg attggatcca aataagtcaa ctatttttat
    40261 tcaaagccag attccagagt tggctgagtt gtctatgtat tatatgaatc tagtttcgtt
    40321 agcacgtttg gagcgaaatc caacagtcaa gacagagatt tctcagaaag gatttggaga
    40381 aagcattccg acaggattct tggtctatcc aatcgctcaa gcagctgata tcacagcttt
    40441 caaggctaat tatgttcctg ttgggacaga tcagaaacca atgattgagc aaactcgtga
    40501 aattgttcgt tcttttaaca atgcatataa ctgtgatgtc ttggtagagc cggaaggtat
    40561 ttatccagaa aatgagagag cagggcgttt gcctggttta gatggaaatg ctaaaatgtc
    40621 taaatcacta aataatggta tttatttagc tgatgatgcg gatactttgc gtaaaaaagt
    40681 aatgagtatg tatacagatc cagatcatat ccgcgttgag gatccaggta agattgaggg
    40741 aaatatggtt ttccattatc tagatgtttt tggtcgtcca gaagatgctc aagaaattgc
    40801 tgatatgaaa gaacgttatc aacgaggtgg tcttggtgat gtgaagacca agcgttatct
    40861 acttgaaata ttagaacgtg aactaggtcc tattcgtgag cgccgtattg aatttgctaa
    40921 ggatatggga gaagtttata atatgattca aaaaggtagt gaaagagcgc gtgaagttgc
    40981 gggtcaaacc ctatctgagg taaaaggggc aatgggactt cattacttta actaagttta
    41041 ttttacaaga aactatcatt tctatctcga agaaaagata gttttttatt tacccctgta
    41101 acatttgaca aatttttata gaatggtatg atagatacaa tataaaaaga gtcaagctca
    41161 aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga cactaaattt ttgaaaaaag
    41221 gttttacctt tgatgatgta ttgcttattc cagctgaaag tcatgtgttg cctaacgatg
    41281 cagatttaac aactaaattg gcagataatt tgactttaaa tatcccaatt attaccgctg
    41341 ccatggacac agttacagag agtcaaatgg ccattgctat tgctcgtgca ggtggtctcg
    41401 gagttatcca taaaaacatg tcaattgctc aacaagcaga cgaggttcgt aaggtaaaac
    41461 gttctgaaaa tggagttatt attgatccgt tcttcttgac gcctgaacat acaattgctg
    41521 aagcagatga gcttatgggt cgttaccgca tcagtggtgt tccagttgtt gaaacacttg
    41581 aaaatcgtaa attggttggt attttgacaa accgagatct tcgttttatt tcagattata
    41641 atcaaccaat ttcaaaccat atgactagtg aaaatcttgt tactgctcct gtgggtacgg
    41701 atcttgcaac ggctgagagt attcttcaag agcatcgtat tgaaaaactt ccgttggtcg
    41761 atgaagaagg cagtctttct ggtttgatca ctatcaaaga tattgaaaaa gttattgagt
    41821 ttccaaatgc ggctaaagat gaatttggtc gtcttctagt tgcaggtgca gtaggtgtta
    41881 cttcagatac atttgaacgt gcagaggctc tttttgaggc aggagcggat gcgattgtta
    41941 ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa aattgccgag attcgtgctc
    42001 atttcccaga tcggactttg attgctggaa atattgctac tgctgaaggt gcacgtgccc
    42061 tttatgaagc gggtgtagac gttgttaagg ttggtattgg accaggttct atctgtacta
    42121 ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc tatctacgat gctgcagctg
    42181 ttgcgcgcga atatggtaaa acgattattg ctgacggtgg gatcaagtat tctggagata
    42241 ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct tggatctatg tttgctggaa
    42301 ctgatgaagc tccaggcgaa actgaaatct tccaaggacg taaattcaag acttaccgtg
    42361 gtatgggatc aattgctgct atgaagaaag gttcaagcga ccgttatttc caaggttcta
    42421 tcaatgaagc aaacaagctc gttccagaag gaattgaagg tcgtgttgct tataaaggag
    42481 cggcagctga tattgttttc caaatgattg gtggtattcg ctctggtatg ggttactgtg
    42541 gtgcagctaa ccttaaagaa ctacacgata atgctcaatt tattgaaatg tctggtgctg
    42601 gtttgaaaga aagccatcct catgatgtgc aaattactaa tgaggcacca aattattcta
    42661 tgtaaaaaat caaaaccacc agtgtgaact ggtggtttgt tctgcggcta taagccgctt
    42721 ctaccggcca gggccaaagg cccaccgaaa tagcttcctc gcgcaccact ttcccgagca
    42781 ggtgctaaag caccttagtt acttcctctt atttatttcg ccagtaaacg gatctactga
    42841 ctcgaataac gtgagctggt ctgctactct gtcttcttgt aattgattct gaatatattc
    42901 agctatcact ttctgattac ggcctaccgt atctacataa tagcctctac accaaaactt
    42961 gcgattgcca tatttgtatt ttaaattcgc atgcttatca aaaatcatca aactgctctt
    43021 gccctttaaa tagcccataa aggacgaaac actaagtttc ggaggaatac tgataagcat
    43081 gtgaatatgg tctgaacaag cattcgcttc atggattatt acacccttac gctcacataa
    43141 gtcacgtatg attcttccga tactagcttt gtatctgcca taaatgattt gacgacgata
    43201 tttgggtgca aaaacaatat gatatttaca attccatgtg gtatgtgata aactttgatt
    43261 atcctctctc atgaggtacc tcctgtatga tatgttgtag tggcggagaa accacttcta
    43321 tcttatcatt ttaggaggtt ctttttgtta ccacgctaaa agctctatgg aaccactagc
    43381 atagctagtg gttttcggga gacaacaatg aaaagaactc cagtgaaaac aggagttctt
    43441 ttacaatgtt gtcaatttcc atttacagca gctttaccat cctgaatagt gaagatactt
    43501 agattttctg gtagattttg aagatggtct aagcttgttg ttgtgataaa ggtttggatt
    43561 gattgagaaa tcgtttctaa taattttaat tgtctagtgt tgtcaagttc actcatcaca
    43621 tcgtcaagca gtaatatagg agattctgtg gtaatgcttt ccattaattc gatttctgct
    43681 aattttatcg agaggacgag actacgatgt tgaccttggc ttccgaaact agcatccatc
    43741 ccatttatat aaaaagaaat gtcatctcga tgaggaccga caccagtatt ctttttaaat
    43801 aaatctctgg atttactttt ttctaaagca attttgaaag attcggataa gttttgtttg
    43861 tcagttatat tgacagaaga ttgataggat attgacaact cttcgatctg attagagagt
    43921 tcaaaatgtt tcttacgccc aaatgattct agttttttta tgaaatctaa gcggtgattc
    43981 attacacgac atccataatc aactagctga tcatctaaca cagaaaggaa tgtttcatct
    44041 attttttgat ctgattttag gtaagtgttt ctttgcttta ggatgtggtt ataattggtt
    44101 aagtcagata agtagattgg cttaatttgc ccaagttcca tatcaatgaa ttttcgtcga
    44161 atcgaaggtg ctcctttaat tagttgtaaa tcttcaggag caaataagac aacattcatg
    44221 tgtcctacat aatctgaaag gcgtgcctgt tttaagtgat taacttttgt tacacggcct
    44281 ttttgtgtta gttcgatttc taggggaatg gatccagttt ttttctgaac gagacctgaa
    44341 agatgaagtt gttcctcatc aaaatgaatg agatttttat ctgttcgagt tcgatgacta
    44401 cgcgttaagg ctaaaaaata gatagcctct aacatgtttg tttttccttg tgcattacgt
    44461 cccaaaaaga cattcaattt aggattaaag tctattttcg tttctttgta attacgaaaa
    44521 gtcttgagag atagatgttg tagccacatg attatctacc agggaatcgt ggagcttgtt
    44581 ggcttttagg tgatgaagca ggtttcgatt tgtctttttt aactccctta ttcatctttt
    44641 tgacaagttt agcgatctgt tctttttcaa ctttatcagc ttggtattca tctggttctt
    44701 cagaagtagg ttgtgtcaac aagatgtcaa tgttcatgtc agggatgtca actttatcgc
    44761 caatacgaag tttttttcca cgacgactct ctaattccct attaaagtaa acagaatgtt
    44821 cagagagaaa tgatttaata gctcctccgc tatgtgtaat tccaagttct ttgagtagtg
    44881 cttggagggt aataaattct tcaaataatt tgtattccat aattcacctc aatctttggt
    44941 attataccat attttcctaa aaatagtgag agagacagcg agaaatgtaa gcgattttta
    45001 tttcaaaagt gttacaggga acaagaaaat ttcaggtttt cgtgatataa tagaagtctg
    45061 tatataagga ggtaaatcat ggagttagtg catggaattt caacacattt tatccaatca
    45121 aaaaagttta aaacaaacaa aattaccgtg cgttttaccg ctccattatc ccttgatacg
    45181 attgcaggtt acatgttgag tgcaagtatg ctagagactg ctaatcagat gtaccccact
    45241 tctcaagatt tgaggagaca cttggccagt ctatacggta cagatatgtc aaccaattgt
    45301 ttcagaagag ggcaaagcca cattatagaa ttgacattta cctatgttcg tgatgagttt
    45361 ttaagtagga aaaacgtgct aacctctcag attttggaac ttgtaaaaga aactcttttt
    45421 tcacccgtag tagttgataa tgggtttgat ccggccttat ttgaaattga gaaaaaacaa
    45481 ttgctagcaa gtttagcagc tgatatggat gattcttttt attttgcaca taaagaattg
    45541 gataaattgt tttttcatga tgaacgtctt caattggaat atagtgattt acgaaatcgt
    45601 attttagctg aaactccaca aagttcttat tcttgtttcc aagaattttt agccaatgat
    45661 cgaatagatt tctttttcct aggtgatttt aatgaggttg aaattcaaaa tgtattagaa
    45721 tcatttggct ttaaaggtcg aaaaggagat gtgaaggttc agtattgtca accttattct
    45781 aatatccttc aggaaggtat ggttcggaaa aatgtgggac aatccatttt ggaattaggt
    45841 tatcattacc gttctaaata tggtgatgag caacatttac ccatgattgt aatgaatggt
    45901 ttacttggtg gatttgctca ctctaagctc tttacaaatg tccgtgaaaa tgctggatta
    45961 gcttatacca tttcaagtga gcttgattta tttagtggat tcttgaggat gtatgctggt
    46021 atcaatcgag aaaatcgtaa ccaggctcgt aaaatgatga ataatcaact gcttgattta
    46081 aaaaaaggtt attttacaga gtttgagtta aatcagacca aggaaatgat tcgttggtcg
    46141 ttgttacttt ctcaagataa tcaatcttca ttgattgaac gtgcttatca aaatgcctta
    46201 tttggaaaat cttcagcaga ctttaaaagt tggattgcaa agcttgaaca aattgacaaa
    46261 gatgctattt gtagagtagc taataatgtg aaactacaag cgatttactt tatggaagga
    46321 atagaatgac aaaggttgtt tttgaagaaa aatactatcc agctgtaaaa gaaaaggttt
    46381 atcgaactcg tttggccaac ggattgacag ttgctctttt gcctaaaaag gaatttaaag
    46441 aggtttacgg gagtgtaact gtacagtttg gttcggtaga tacgtttgtc acagaagttg
    46501 acgggtatgt aaaacaatat cctggaggaa ttgctcattt tcttgaacat aaattatttg
    46561 agagagaaga ttctagtgat ttgatgtcgg cttttacgag tctaggtgca gatagtaatg
    46621 cctttacaag ctttacaaaa acaaactatc ttttttcagc aacggattat tttttagaaa
    46681 atttagattt acttgatgaa ttggtaacat cagcacactt tactgaagct tccattctga
    46741 cagagcagga tattattcag caagaacgag aaatgtacca agatgatcca gattcgtgtt
    46801 tattcttttc aactttagcg aatttgtatc ctggtacacc tttagcaact gatatagttg
    46861 gaagtgagga gtccatttcc caaatcaatc taactaattt gcaagaaaat tttacaaagt
    46921 tttacaaacc tgtaaacatg tctctgtttt tagttggtaa ttttgatgtg gagcgagtac
    46981 aggactattt tgaaagcaaa gaactgaaag attcagattt tcaggaagta gcaagagaaa
    47041 agttgttttt acagcctgta aagccaacag atagtatgag aatggaagta tcttctccca
    47101 aactagcgat tggagttaga ggtaagcgag aagtttctga agcggattgc tatcgacatc
    47161 atattttatt aaaattattg tttgcaatga tgtttggttg gacttcggat cgttttcaaa
    47221 aatgttatga atcaggtaaa attgatgcat ccttatctct ggaagttgaa gtaacaagtc
    47281 gctttcattt tgtcatgttg acaatggata cgaaagagcc agttgctttg tctcatcaat
    47341 ttaggaaggc tattcgtaat tttacaaagg atttagatat tacagaggaa catttagata
    47401 ttatcaaaag agagatgttt ggcgaatttt tcagtagcat gaactctctt gaatttattg
    47461 caacgcaata tgatgctttt gaaaatggtg agacaatttt tgatttgccg aaaattttac
    47521 aggaaattac tttagaggat gttcttgatg ctggacatca tttaatagat gatggtgaca
    47581 tagttgattt tacaatattc ccatcgtagt aacctatcat aatagacact agaaagaagg
    47641 gatgacaagt atgagaaaaa aaacaattgg agaggtttta cgattagcta gaatcaatca
    47701 gggattgagt ttagatgaat tgcagaaaaa gacagagatc cagttagata tgttggaagc
    47761 aatggaagca gacgatttcg atcaacttcc aagtcctttt tacacgcgtt ctttcttgaa
    47821 aaaatatgca tgggctgttg agttagatga ccaaattgtt ttggatgctt atgattctgg
    47881 gagtatgatt acttatgagg aagtagatgt tgatgaagat gagttgacag gtcgtagacg
    47941 ttcaagtaag aaaaagaaga aaaaaacatc atttttacct ttattttatt ttatcctttt
    48001 tgctttatcg attttaattt ttgtgactta ttatgtttgg aactatattc aaactcaacc
    48061 agaggagcct tctctttcta attacagtgt ggttcaatca acaagttcaa ctagctctgt
    48121 tccccactcc tcaagtagta gttcttctag tatagaatca gctataagtg tatcaggcga
    48181 aggaaatcat gtagaaatcg cttataagac aagtaaggaa acagttaaat tgcaattggc
    48241 agtttcagat gttacaagtt gggtcagtgt ttcagaaagc gaacttgagg gcggtgtaac
    48301 cttatcgcca aagaagaaaa gtgcagaagc aacagttgca actaaaagtc ctgtaacaat
    48361 tacgttaggt gttgtaaaag gtgttacttt gacagtagat aatcagactg ttgatttatc
    48421 gaaattaaca gctcagactg gacaaatcac tgtaaccttt actaaaaatt aaggaaaaac
    48481 gaatgaaaaa agaacaaatt cccaatctct taacaatagg tcgaattctc tttataccta
    48541 tttttatctt tattttaacg ataggaaatt cgatagagag tcatatagtt gcagctatta
    48601 tctttgctgt tgccagtatt accgactatt tagatggata tttagctcgt aaatggaatg
    48661 tggtcagtaa ttttggtaaa tttgcagatc ctatggcgga taagttacta gttatgtcgg
    48721 cttttattat gttgattgag ttaggtatgg ctccggcttg gattgttgca gtgattatct
    48781 gtcgtgagtt agctgtgaca ggtttaaggc ttttattggt tgaaactggt ggaacaattt
    48841 tagcagcagc aatgcctgga aaaattaaaa cttttagtca gatgtttgct attattttct
    48901 tgctattaca ttggactttg cttggtcaag ttctacttta tgtagcctta tttttcacta
    48961 tctactctgg ctatgactat ttcaagggta gtgcctatgt atttaaaggg acatttggtt
    49021 cgaaatgaaa tcaataattg atgtaaaaaa tctttctttt cgctataaag aaaatcagaa
    49081 ctactacgat gtgaaggata ttacgtttca cgtgaaacgt ggagaatggc tttcgattgt
    49141 agggcataat ggtagtggta aatcaacgac ggttcgatta attgatggct tactggaagc
    49201 agaatccgga gagattgtaa ttgatggcca acgtttgact gaggaaaatg tttggaatat
    49261 acgtcgtcaa atcggtatgg tttttcaaaa tccagacaat caatttgttg gagcgactgt
    49321 tgaagatgat gttgcttttg gtttggaaaa tcagggactt tctcgtcaag aaatgaaaaa
    49381 gagagtagaa gaagctctgg ctttagttgg catgttggac tttaaaaaga gagagccagc
    49441 gcgtctatca ggtggccaaa agcaacgtgt ggccattgca ggtgttgtag ccctaagacc
    49501 agctatttta atcttagatg aagcaacgag tatgttggat cctgaggggc gtagagaact
    49561 tattgggaca gtaaaaggaa ttcgaaaaga ctatgatatg acggtcattt ctattaccca
    49621 tgatttggaa gaagtcgcca tgagtgatcg cgtattggtc atgaaaaaag gggaaattga
    49681 atcaactagt agtccaaggg agcttttctc tcgaaatgat ttagatcaaa ttggattaga
    49741 cgatcctttt gctaatcaat taaaaaaatc tttgagccag aatggctatg atttacctga
    49801 aaattatttg acagaaagtg agctagagga taagctatgg gaattgctct agaaaatgtg
    49861 aattttacat atcaagaagg tactccctta gcttcagcag ctttgtcgga tgtttctttg
    49921 acgattgaag atggctctta tacagcttta attgggcaca caggtagtgg taaatcaact
    49981 attttacaac tcttaaatgg tttattggtg ccaagtcaag ggagtgtgag gatttttgat
    50041 accttaatca cctcgacttc taaaaataaa gatattcgtc aaattagaaa acaggttggc
    50101 ttggtatttc agtttgctga aaatcagatt tttgaagaaa cggttttgaa ggacgttgct
    50161 tttggaccgc aaaattttgg agtttctgaa gaagatgctg tgaagactgc gcgtgagaaa
    50221 ctggctctgg ttggaattga tgaatcactt tttgatcgta gtccgtttga gctgtcaggg
    50281 ggacaaatga gacgtgttgc cattgcaggc atacttgcca tggagccagc tatattagtc
    50341 ttagatgagc caacagctgg tctagatcct ctagggagaa aagagttgat gaccctgttc
    50401 aaaaaactcc accagtcagg gatgaccatc gtcttggtaa cgcatttgat ggatgatgtt
    50461 gctgaatatg caaatcaagt ctatgtaatg gaaaagggac gtttagtaaa ggggggcaaa
    50521 ccaagtgatg tctttcaaga cgttgttttt atggaagaag ttcagttggg agtacctaaa
    50581 attacggcct tttgtaaacg attggctgat agaggcgtgt catttaaacg attaccgatt
    50641 aagatagagg agttcaagga gtcgctaaat ggatagtatg attttggggc gttatatccc
    50701 aggggattcg attgttcacc gattggatcc acgtagcaaa ttgcttgcta tgatgctact
    50761 gattttgatt gtgttttggg ctaataaccc cttgacgaat ctgattcttt ttatagcgac
    50821 agggatattt attgccttgt caggagtatc tctttcattt tttattcagg gcttgaagtc
    50881 tatgtttttc ttgattgcct tcacaactat ttttcaacta tttttcattt ctaatgggaa
    50941 tgttttattt gagttttcgt ttgtgagaat cacggattat gctttgcaac aagctgggat
    51001 tattttttgt cgctttgtat tgattatttt cttttcaact ttgttaacct taacaaccat
    51061 gcctttaagt ttggcatcag ctgtcgaagc tttattagca cctttaaagc gtgtgaaagt
    51121 tccagttcat gaaattggat tgatgctgtc tatgagtttg cgttttgtcc caaccttgat
    51181 ggatgatacg actcggatta tgaatgcaca gaaagctcgt ggagtggatt ttggagaagg
    51241 aagcatcgtt caaaaagtaa aggcgatgat tcccattttg attcctcttt ttgcgacaag
    51301 tttaaaacgt gcagattcct tggctatcgc tatggaagcg cgtggctatc agggtggaaa
    51361 aggcagaagt caataccgac aattgaaatg gactctaaag gatacgctga ccattcttgt
    51421 tattctcgta cttggttgtt gtttattttt cttaaaatct tagtagcttt caggaattga
    51481 taaaaagtta ctgtaacagt ttttgatata aaggtaggaa tatgaaccgt tttaaaaaat
    51541 caaaatatgt cattattgtt tttgtcactg ttctgcttgt gtcagctctc ttagcgacga
    51601 cttattcaag tacagttgtg acaaaattag gagatggaat ctcattggtt gatagagttg
    51661 tacaaaaacc ttttcagtgg tttgattctg tcaaatcaga tttggctcat ttgacacgaa
    51721 catataatga aaatgaaagt ttgaagaaac agctttacca attagaagtt aaatcaaatg
    51781 aggtggaaag tttaaagaca gaaaatgaac aactgcgcca attgcttgat atgaagtcta
    51841 aattgcaagc cacaaagact ttagcagcag atgttattat gcgttctccg gtatcttgga
    51901 agcaggagtt gaccttagat gcaggtagat caaaaggtgc ttctgagaac atgttagcta
    51961 ttgcaaatgg tggcttgatt gggagtgttt caaaagtaga ggagaactct actatagtca
    52021 accttctgac aaatacggaa aatgctgata agatttctgt taaaattcaa catggctcta
    52081 ctacaattta tggaattatt attggctatg acaaggaaaa tgacgttctt aaaattagcc
    52141 aattaaatag taatagcgat attagtgcgg gagataaggt gactactggt ggattaggaa
    52201 actttaacgt tgctgatatt cctgttggtg aagtggttgc cacaacgcat agtacagact
    52261 atttgacacg agaagtaact gttaaattga gtgcagatac tcataatgta gatgtgatag
    52321 aattagtggg gaattcataa tgagacagtt gaagcgagtt ggagtatttt tattgcttcc
    52381 tttctttgtt ctaattgacg cccatattag ccagcttctg ggctcatttt tcccccatgt
    52441 acatttggct agtcattttc tttttctatt tctcttattt gagacgatag aagtatcaga
    52501 gtatctctac ctagtctatt gttttgttat aggcttggtt tatgatgttt actttttcca
    52561 tctaataggg attacaactc tcttatttat cttattggga gccttccttc ataaattgaa
    52621 tagtgttatt ttgttgaatc gttggacaag aatgctagct atgattgtgc tgacattcct
    52681 gtttgaaatg ggtagttatc ttttggcttt tatggtaggg ttgacagtag atagcatgtc
    52741 gatttttata gtctatagct tggtaccgac gatgatttta aattttttat ggattactgt
    52801 ttttcaattt atttttgaaa aatattatct ataagaacga catataaatg taacaaaggc
    52861 gtaatattta ttaggccttt ttttggtata ctagtattgt ctttaaaaga aggagtatct
    52921 acgtaatatg aagaaaaaaa tcttagcgtc acttttatta agtacagtaa tggtttctca
    52981 agtagctgtt ttaacaactg cgcatgcaga aacgactgat gacaaaattg ctgctcaaga
    53041 taataaaatt agtaacttaa cagcacaaca acaagaagcc caaaaacaag ttgaccaaat
    53101 tcaggagcaa gtatcagcta ttcaagctga gcagtctaac ttgcaagctg aaaatgatag
    53161 attacaagca gaatctaaga aactcgaggg tgagattaca gaactttcta aaaacattgt
    53221 ttctcgtaac caatcgttgg aaaaacaagc tcgtagtgct caaacaaatg gagccgtaac
    53281 tagctatatc aataccattg taaactcaaa atcaattaca gaagctattt cacgtgttgc
    53341 tgcaatgagt gaaatcgtat ctgcaaacaa caaaatgtta gaacaacaaa aggcagataa
    53401 aaaagctatt tctgaaaaac aagtagcaaa taatgatgct atcaatactg taattgctaa
    53461 tcaacaaaaa ttggctgatg atgctcaagc attgactacg aaacaggcag aactaaaagc
    53521 tgctgaatta agtcttgctg ctgagaaagc gacagctgaa ggggaaaaag caagtctatt
    53581 agagcaaaaa gcagcagctg aggcagaggc tcgtgcagct gcggtagcag aagcagctta
    53641 taaagaaaaa cgagctagcc aacaacaatc agtacttgct tcagcaaaca ctaacttaac
    53701 agctcaagtg caagcagtat ctgaatctgc agcagcacct gtccgtgcaa aagttcgtcc
    53761 aacatacagt acaaacgctt caagttatcc aattggagaa tgtacatggg gagtaaaaac
    53821 attggcacct tgggctggag actactgggg taatggagca cagtgggcta caagtgcagc
    53881 agcagcaggt ttccgtacag gttcaacacc tcaagttgga gcaattgcat gttggaatga
    53941 tggtggatat ggtcacgtag cggttgttac agctgttgaa tcaacaacac gtatccaagt
    54001 atcagaatca aattatgcag gtaatcgtac aattggaaat caccgtggat ggttcaatcc
    54061 aacaacaact tctgaaggtt ttgttacata tatttatgca gattaattta cagagggact
    54121 cgaatagagc cctcttttca ggttttaccg tgacaatccc tattaaaaat tatatcaaaa
    54181 tagcttgaaa atattggaaa agtatggtaa aatgaaaatt gtcgtgtgaa cgataatact
    54241 cattcttgat gaattgtgaa gcagttgccc ttgggtcgtt ttgcgagttg aagtcaagaa
    54301 gaggaaaaaa acaaaaagga gaaatactca tggcagtaat ttcaatgaaa caacttcttg
    54361 aggctggtgt acactttggt caccaaactc gtcgctggaa tcctaagatg gctaagtaca
    54421 tctttactga acgtaacgga atccacgtta tcgacttgca acaaactgta aaatacgctg
    54481 accaagcata cgacttcatg cgtgatgcag cagctaacga tgcagttgta ttgttcgttg
    54541 gtactaagaa acaagcagct gatgcagttg ctgaagaagc agtacgttca ggtcaatact
    54601 tcatcaacca ccgttggttg ggtggaactc ttacaaactg gggaacaatc caaaaacgta
    54661 tcgctcgttt gaaagaaatt aaacgtatgg aagaagatgg aactttcgaa gttcttccta
    54721 agaaagaagt tgcacttctt aacaaacaac gtgcgcgtct tgaaaaattc ttgggcggta
    54781 tcgaagatat gcctcgtatc ccagatgtga tgtacgtagt tgacccacat aaagagcaaa
    54841 tcgctgttaa agaagctaaa aaattgggaa tcccagttgt agcgatggtt gacaccaata
    54901 ctgatccaga tgatatcgat gtaatcatcc cagctaacga tgacgctatc cgtgctgtta
    54961 aattgatcac agctaaattg gctgacgcta ttatcgaagg acgtcaaggt gaggatgcag
    55021 tagcagttga agcagaattt gcagctttag aaactcaagc agattcaatt gaagaaatcg
    55081 ttgaagttgt agaaggcgac aacgcttaat ttatacaaat agtaattacc taggagggcg
    55141 gggcttagcc cggctctcct attttcaaaa aatataggag aattaaaatg gcagaaatta
    55201 cagctaaact tgtaaaagag ttgcgtgaaa aatctggtgc cggtgttatg gacgctaaaa
    55261 aagcgcttgt agaaacagac ggtgacatcg aaaaagcgat tgaattgctt cgtgaaaaag
    55321 gtatggctaa ggcagctaag aaagctgacc gtgttgctgc agaaggtttg actggtgttt
    55381 atgttaacgg taatgttgca gcagttattg aagtaaacgc tgaaactgac ttcgttgcaa
    55441 aaaacgctca attcgttgaa ttggtaaata ctacagctaa agtcattgct gaaggaaaac
    55501 ctgctaacaa cgaagaagct cttgctttga taatgccttc aggtgaaact cttgaagctg
    55561 catacgtatc tgcaacagca actatcggag agaaaatctc attccgtcgc tttgcattga
    55621 ttgaaaaaac agacgcacaa cactttggag cataccaaca taacggtgga cgtatcggtg
    55681 ttatttcagt tgttgaaggt ggagacgaag cacttgctaa acaattgtca atgcacatcg
    55741 cagcgatgaa accaacagtt ctttcttaca aagaattgga tgagcaattc gttaaagatg
    55801 agttggcaca attgaatcac gttatcgacc aagacaacga aagccgtgca atggttaata
    55861 aaccagctct tccacacttg aagtatggat caaaatctca attaactgat gatgttattg
    55921 ctcaagctga agctgacatc aaagctgaat tggctgcaga aggcaaacca gaaaaaatct
    55981 gggacaaaat tattccaggt aaaatggatc gcttcatgct tgataacact aaagttgacc
    56041 aagcttacac acttcttgca caagtttaca tcatggatga cagcaagaca gttgaagcat
    56101 accttgaatc agttaacgct tcggtagttg agtttgctcg ctttgaagtt ggtgaaggta
    56161 tcgagaaagc tgcaaacgac ttcgaagctg aagttgcagc tacaatggca gcagccttga
    56221 ataactaata atagaaagga agcaaattgc ttcctttttt gtatagggct tagatttttc
    56281 ctgaaattgt tttttcccca gtctcactcg attagaataa ttaaaacaaa aagccctata
    56341 ataagggcta agtgcattta ggagactata cttcaaattc atagtaagcg cgtcataaca
    56401 aggtatctat cctaattccc caacttccag tatactagat aaaaaataat tatcggagga
    56461 aaggtattgt actatgatga ttcaactaag tgatttaggt caagttcaca ttgtttgtgg
    56521 caagacagat atgaggcagg gaatagactc attagcctat gtagttaaaa cccactttga
    56581 attggattct ttctccggtc aagtctttct cttttgtggt ggacgtaaag accgctttaa
    56641 agccctttac tgggatggtc aaggattttg gctactatat aaacgctttg agaacgtcag
    56701 actgacttgg cccagtacag aaaaggatgt caaagctctc acacctgaac aagtagactg
    56761 gcttatgaag ggcttttcta tcactccaaa aataaatcca tcagaaagtc gtgatttcta
    56821 ttgaaatgag gactttcttt ttatactcat ctgctttcaa aaagcattct agtccatctc
    56881 cgattaacga tggactttat cacatccttc tccagtcctt gtataacatc ttggagttga
    56941 ttcatgacat cttccaaagt ttaaaaggct ttattcttaa atccacgttt acgaatctct
    57001 ttccacactt gttcaatggg gttcatctct ggtgtgtatg gaggaataaa tgcaaagcca
    57061 atattagtcg gaatctttaa ggtacttgat ttatgccata tagcattgtc cataacgagt
    57121 aaaagataat catctggata agcttgtgaa atctcctatt cctaaagccc ctttagcgca
    57181 taactttggc tcagcttcta ttatcgctca caccatccat cagaagttta atctgaaggt
    57241 acccaattat cgccaagaag aagattgggc taggatgggt ttaccaatca cacgtaagga
    57301 aatctctaat cggcatatca agacgagtca atactatttg gagccccttt ataacctctt
    57361 gcgagagaga ctattgactc agcccttact tcatgcggat gaaacttctt atagggtgct
    57421 agagagtgat agtcagctga cttactattg gacttttttg tctgggaaag ctgagaaaca
    57481 agggattacg ctttaccatc atgtcctaat cgatttgttc atatcttatt tcaatccatt
    57541 ataaatagtg agaaatatct atcctatctt ctagaatgtc ttccaaacgt ggaaactctc
    57601 gtaaacaaag aggttttaga ggcctattta ccatggacta aagttgtaca agaaaagtgc
    57661 aaataagaaa tctccagatt aggaactatc cgtgagttct ctagtctgga gatttttcaa
    57721 tatacttcgt tattggacgg ttacaattca taaagtgctg tagagagata acgttcaccg
    57781 ttatctggtg ctagggcaag gactttttta cctgtaccta attttttggc aacctcgatg
    57841 gctccgtaga tagctgcagc tgaggaaatc cctacaagga agccttcttt tccaccaatt
    57901 tcacgtccga gtgcaagagc gtcatctgat gttacacgaa cgataccatc ataggcttta
    57961 gtatcaagtg tatcaggaat aaatccagct gagatacctt gaattttgtg aggaccaggt
    58021 ttttcaccag atagaatagc agattcatct gcttctactg caaaaacttg aatgttagaa
    58081 ttttctgatt tgagtgcatg agaaacacca gaaatcgttc caccggtacc tactccagca
    58141 acaaaggcat ctaatccatc tttaccgaaa gcagctagta tctcagctcc tgttgttctt
    58201 tcgtgtactt ctggattagc tggattgtca aattgaagag gaaggaaacc atcacgttca
    58261 gcagcgattt cttgagcctt agcaatagca cctttcattc cctcgctacc aggagttagg
    58321 acgagttcag caccataagc ttggataatt ttacgtcgtt ctacactcat agtttcaggc
    58381 ataacgatga cgactttata ccctttagca gcacctaccc atgaaagtcc aataccagtg
    58441 tttccacttg ttgcttcaac aatagtagaa ccaggtttca gaataccatc ttgttcagct
    58501 ttttcaatca tgctaagggc aatacggtct tttacagatg aaccaggatt aaatgcttca
    58561 agctttatat agacgtctgt agcaccttct ggcacgatgt tgttaagttt aacaatcggt
    58621 gtttgaccga ttaattcagt aatgttgtta taaatagaca tatgaatacc tctttgtata
    58681 agatatcttt agtataacgt tatctatacc atttgtaaaa tatagaaatc ctatcgaagc
    58741 gataggattt ctatatatca tagatcaaag tcattaattt tcaagtgatt gcgttcagct
    58801 aattctagta aataggtgtg aaggaaaacg atatcaggtt tcgtttgaat tgcttcattt
    58861 tctagtatat tttggtacgc atctttttat tttgctcgct aaagtagttg tgagaatgtc
    58921 aacgaaacgc tgtattattc attgtttaca ctaagtttac aggaacttca acctctcgta
    58981 aaccttggtc agttaaagtg acttttccat taaaaaactc cacaagtgca gctttaatag
    59041 tttctttttc ttctttatca acataaatca tcgtatcgac ttgatctgta aagtttgtat
    59101 ccagctccat gagatcatgt tctttaagga agttactgta ctcttggtac tgagcataag
    59161 acatttgaat agcaatgcca gcctgttctt ttatttcaat aataccaatt tctttgacag
    59221 ctaaggcgac actgccggcg taagcacgaa ttagtcctcc agcgcctagt ttaataccac
    59281 caaagtagcg tgtcacgacc acacagacat tggtgagatt gtgattttct agtaccccaa
    59341 gcatgggaac accagcagta ccactaggct caccatcatc acttgtacgt ttaatttcac
    59401 tacgttctcc aataataaag gcagagcagt tatgtgtcgc tttgtagtgt tcttttttga
    59461 tggcagtaat gaagtcacga gcctcttctt cgctataaac acgcttggca tggcagataa
    59521 agcgagattt tttgatttct tcttggactt ggccgtcctc tttaattgtc ctaaattcca
    59581 tgatttaatt gtactaaaaa atcatctaaa gtgctagttt ttacgaataa agaagtatga
    59641 aagtaaattt agattatctc ggtcgtttat ttactgagaa tgaattaaca gaagaagaac
    59701 gtcagttggc ggagaaactt ccagcaatga gaaaggagaa ggggaaactt ttctgtcaac
    59761 gttgtaatag tactattcta gaagaatggt atttgcccat cggtgcttac tattgtcgag
    59821 agtgcttgct gatgaagcga gtcagaagtg atcaaacttt atactatttt ccgcaggagg
    59881 attttccgaa gcaagatgtt ctcaaatggc gcggccaatt aactcctttt caagagaagg
    59941 tgtcagaggg actgcttcaa gcagtagaca agcaaaagcc aaccttagtt catgcggtaa
    60001 caggagctgg aaagacagaa atgatttatc aagtagtggc taaagtgatc aatgcgggtg
    60061 gtgcagtgtg tttggctagt cctcgcatag atgtttgttt ggagctgtac aagcgcctgc
    60121 aacaggattt ttcttgcggg atagctttgc tacatggaga atcggaacct tattttcgaa
    60181 caccactagt tgttgcaaca acccatcagt tattgaagtt ttatcaagct tttgatttgc
    60241 tgatagtgga tgaagtagat gcttttcctt atgttgataa tcccacgctt taccacgctg
    60301 tcaagaatag tgtaaaggag aatggattga gaatcttttt aacagcgact tcgaccaatg
    60361 agttagataa aaaggtccgt ttaggagaac taaaaagact gagtttaccg agacggtttc
    60421 atggaaatcc gttgattatt ccaaaaccaa tttggttatc ggattttaat cgctacttag
    60481 acaagaatcg tttgtcacca aagttaaagt cctatattga gaagcagaga aagacagctt
    60541 atccgttact catttttgct tcagaaatta agaaagggga gcagttagca gaaatcttac
    60601 aggagcaatt tccaaatgag aaaattggct ttgtatcttc tgtaacagag gatcgattag
    60661 agcaagtaca agcttttcga gatggagaac tgacaatact tatcagtacg acaatcttgg
    60721 agcgtggagt taccttccct tgtgtggatg ttttcgtagt agaggccaat catcgtttgt
    60781 ttaccaagtc tagtttgatt cagattggtg gacgagttgg acgaagcatg gatagaccga
    60841 caggagattt gcttttcttc catgatgggt taaatgcttc aatcaagaag gcgattaagg
    60901 aaattcagat gatgaataag gaggctggtc tatgaagtgc ttgttatgtg ggcagactat
    60961 gaagactgtt ttaactttta gtagtctctt acttctgagg aatgatgact cttgtctttg
    61021 ttcagactgt gattctactt ttgaaagaat tggggaagag aactgtccaa attgtatgaa
    61081 aacagagttg tcaacaaagt gtcaagattg tcaactttgg tgtaaagagg gagttgaagt
    61141 cagtcataga gcgattttta cttacaatca agctatgaag gattttttca gtcggtataa
    61201 gtttgatgga gacttcctgt taagaaaagt tttcgcttca tttttaagtg aggagttgaa
    61261 aaagtacaaa gagtatcaat ttgttgtaat tcccctaagt cctgatagat atgctaatag
    61321 aggatttaat caggttgagg gcttggtaga ggcagcaggc tttgagtatc tggatttatt
    61381 agagaaaaga gaagagagag ccagttcttc taaaaatcgt tcagagcgct tggggacaga
    61441 acttcctttc tttattaaaa gtggagtcac tattcctaaa aaaatcctac ttatagatga
    61501 tatctatact acaggagcaa ctataaatcg tgttaagaaa ctgttggaag aagctggtgc
    61561 taaggatgta aaaacatttt cccttgtaag atgaggaaaa aatttgcaaa aatagaatga
    61621 aagcgttata ataaaatcat aaaaacaaaa atgtttagaa agaaggtact catatgatta
    61681 aatatagtat ccgtggtgaa aacctagaag taacagaagc aattcgtgat tatgtagttt
    61741 ctaaactcga aaagatcgaa aagtacttcc aaccagaaca agagttggat gcccgaatta
    61801 acttaaaagt ttatcgtgaa aaaacggcta aagtggaagt aacgattccg cttggatcta
    61861 ttactctccg cgcagaagat gtatctcaag atatgtatgg ttcaattgac cttgtaactg
    61921 ataaaattga acgtcagatt cgtaaaaata aaacaaaaat cgagcgtaaa aataaaaata
    61981 aggtagcaac tggtcaatta tttacagatg ctttggtgga agattcaaat gttgtccagt
    62041 ctaaagttgt tcgttcaaaa caaattgatt taaaaccaat ggatttggaa gaagcaattc
    62101 tacaaatgga tttattgggg catgatttct ttatctatgt ggatgttgaa gatcagacaa
    62161 ccaatgtgat ttatcgtcgt gaggatggcg aaattggttt gttagaggtt aaagaatctt
    62221 aatttcaata tgtgtaaagg taggtttact gaattgtaaa ctaccttttt cttataattg
    62281 atagaattac tgattacact tttaaaaagt cgctttttga ggggtattat ggtataatgg
    62341 gtgccaagag gttttgaatg aaaaaatttt atgtaagtcc aatttttcct attctagtag
    62401 gattgattgc gtttggagtc ttatccactt tcattatttt tgttaataat aatctgttga
    62461 cggttttaat tttgtttctt tttgtaggag gctatgtttt tttatttaag aaactgagag
    62521 tgcattatac aaggagtgat gtagaacaga tacagtatgt aaaccaccaa gcggaagaaa
    62581 gtttgacatc tctattggaa caaatgcctg taggtgttat gaaattgaat ttatcttctg
    62641 gagaggttga gtggtttaat ccctatgctg aattgatttt gaccaaggaa gatggtgatt
    62701 ttgatttaga agctgttcaa acgattatca aggcttcagt aggaaatccg tctacttatg
    62761 ccaagcttgg tgagaagcgt tatgctgttc atatggatgc ttcttccggt gttttgtatt
    62821 ttgtagatgt atccagggaa caagccataa cagatgaatt ggtaacaagt cgaccagtga
    62881 ttgggattgt ctctgtggat aattatgatg atttggagga tgcaacttct gagtcagata
    62941 ttagtcaaat caatagtttt gtagctaatt ttatatcaga gttttcagaa aaatacatga
    63001 tgttttctcg tcgggtaagt atggatcgat tttatctatt tactgactac acggtgcttg
    63061 agggcttgat gaatgataaa ttttctgtta ttgatgcttt cagagaagag tcgaaacaga
    63121 gacagttgcc cttgacctta agtatgggat tttcttatgg cgatggaaat catgatgaga
    63181 tagggaaagt tgctttgctc aatttgaact tggctgaagt acgtggtggc gaccaggtgg
    63241 ttgttaagga aaacgacgaa acgaaaaatc cagtttattt tggtggtggg tctgctgctt
    63301 caatcaagcg tacacggact cgtacgcgcg ctatgatgac agctatttca gataagattc
    63361 ggagtgtaga tcatgttttt gtagtcggtc acaaaaattt agacatggat gctttgggct
    63421 ctgctgtagg tatgcagttg ttcgccagca atgtgattga aaatagctat gctctttatg
    63481 atgaagaaca aatgtctcca gatattgaac gagctgtttc attcatagaa aaagaaggag
    63541 ttacgaagtt gttgtctgtt aaggatgcaa tggggatggt gaccaatcgt tctttgttga
    63601 ttcttgtaga ccattcaaag acagccttaa cattatcaaa agaattttat gatttattta
    63661 cccaaaccat tgttattgac caccatagaa gggatcagga ttttccagat aatgcggtta
    63721 ttacttatat cgaaagtggt gcaagtagtg ccagtgagtt ggtaacggaa ttgattcagt
    63781 tccagaattc taagaaaaat cgtttgagtc gtatgcaagc aagtgtcttg atggctggta
    63841 tgatgttgga tactaaaaat ttcacctcgc gagtaactag tcggacattt gatgttgcta
    63901 gctatctcag aacgcgcgga agtgatagta ttgctatcca ggaaatcgct gcgacagatt
    63961 ttgaagaata tcgtgaggtc aatgaactta ttttacaggg gcgtaaatta ggttcagatg
    64021 tactaatagc agaggctaag gacacgaaat gctatgatac agttgttatt agtaaggcag
    64081 cagatgccat gttagccatg tcaggtattg aagcgagttt tgttcttgcg aagaatacac
    64141 aaggatttat ctctatctca gctcgaagtc gtagtaaact gaatgtacaa cggattatgg
    64201 aagagttagg cggtggaggc cactttaatt tggcagcagc tcaaattaaa gatgtaacct
    64261 tgtcagaagc aggtgaaaaa ctgacagaaa ttgtattaaa tgaaataaag gaaaaggaga
    64321 aagaagaatg aaagtaatct ttttagcaga tgttaaagga aaaggtaaaa aaggcgaaat
    64381 taaggaagta ccaacagggt atgcgcaaaa ctttcttatc aaaaagaatc tagccaaaga
    64441 agcgactgct caagctgtag gtgaacttcg tggtaaacaa aaatcggaag aaaaagctca
    64501 cgctgagatg attgcagaag gaaaagcaat taaagcacaa cttgaagcag aagaaactgt
    64561 tgtagaattt gttgaaaaag ttggtccaga tggtcgtacc tttggttcta ttaccaataa
    64621 gaagattgca gaagaattgc aaaagcaatt tggaattaag attgataaac gtcatattca
    64681 agtacaagct ccgattcgag cggttggttt gattgatgtg ccagtgaaaa tctatcaaga
    64741 tatcacaagt gtaatcaatc ttcgtgtgaa agaaggataa gtttacactt tcttgacaag
    64801 attgtaaaag gaagggaagt ctgatggcag aagtagaaga gttacgagta caacctcaag
    64861 atatcttagc tgagcaatcc gttttagggg ctatctttat tgatgagagt aaacttgttt
    64921 ttgtgcgaga atacattgag tctcgggact tttttaagta tgcccatcgt ttgattttcc
    64981 aagccatggt cgatttatcc gatcgtggtg atgccataga tgcaacaacg gttcgtacta
    65041 tccttgataa tcaaggtgat ttacagaata ttggtggctt gtcttacttg gttgagattg
    65101 ttaattctgt gccaacttct gctaatgcgg agtattatgc taagattgtt gcagaaaaag
    65161 caatgctacg tcgtttaatt gccaagttga cagagtctgt caaccaagct tacgaagcgt
    65221 cacaaccagc tgatgaaatt attgctcagg cagaaaaagg gttgattgat gtcagtgaaa
    65281 atgcaaatcg aagcgggttt aagaacattc gagatgtgtt gaatctcaac tttggaaatc
    65341 tggaagctcg ctcgcaacaa acgaccgata ttacaggtat tgcgacaggt tatcgtgatt
    65401 tggatcatat gacaacagga cttcatgagg aggagttgat tatcttagca gctcgtccag
    65461 cagttggtaa gacagcattt gccttgaata tcgctcagaa cattgggact aagttggaca
    65521 aaacggttgc tattttttca ctcgaaatgg gtgcggaaag cttggtagat cgtatgttag
    65581 ctgcagaagg cttggtggag tcacattcta tccgtacagg gcaattgaca gatgaggagt
    65641 ggcaaaaata tactattgct cagggtaatc tagctaacgc cagtatctat atcgatgata
    65701 cgccaggtat tcggattaca gagattcgtt ctcgttctcg taaattggct caagaaactg
    65761 gaaatcttgg tttgattttg atagactatt tgcaacttat cacgggaact ggtcgagaaa
    65821 atcgtcaaca agaagtttct gaaatttctc gtcagttgaa aatactagcc aaggaattga
    65881 aggttccagt aatcgctctg agtcagcttt ctcgtggtgt agaacaacgt caggacaaga
    65941 gaccggtctt gtctgatatt cgtgaatctg ggtctattga gcaggacgct gatatcgtag
    66001 cttttctcta tcgcgatgac tactatgaac gtggtggtga agaagaggag ggtatcccaa
    66061 ataataaggt ggaagttatt atcgagaaaa accgtagtgg agctcgtgga acagtggaat
    66121 tgattttcca aaaagaatac aataaatttt caagtatctc aaagagggag gcataagatg
    66181 tcagatgcat ttacagatgt agccaagatg aaaaaaatca aagaagaaat taaggcacat
    66241 gagggacaag tcgtagaaat gactttggag aatggtcgta agcgccaaaa aaatagattg
    66301 ggtaagctaa ttgaagttta tccatctcta tttattgtgg agtttgggga tgtggaagga
    66361 gataaacaag ttaatgttta cgttgaatcc tttacttact cagatattct tacagaaaag
    66421 aatttgattc attatcttga ctaaagtgag aaattttctc actttttctt ttttctccga
    66481 ataatttagg tgaaggcaat catcgcttta tattattttt taaggaggaa gaatgaaaat
    66541 tttaccgttt atagcaagag gaacaagtta ttacttgaag atgtcagtta aaaagcttgt
    66601 tcctttttta gtagtaggat tgatgctagc agctggtgat agtgtctatg cctattccag
    66661 aggaaatgga tcgattgcgc gtggggatga ttatcctgct tattataaaa atgggagcca
    66721 ggagattgat cagtggcgca tgtattctcg tcaatgtact tcttttgtag cctttcgttt
    66781 gagtaatgtc aatggttttg aaattccggc agcttatgga aatgcgaatg aatggggaca
    66841 tcgtgctcgt cgggaaggtt atcgtgtaga taatacaccg acgattggtt ccattacttg
    66901 gtctactgca ggaacttatg gtcatgttgc ctgggtgtca aatgtaatgg gagatcagat
    66961 tgagattgag gaatataact atggttatac agaatcctat aataaacgaa ttataaaagc
    67021 aaacacgatg acaggattta ttcattttaa agatttggat ggtggcagtg ttgggaatag
    67081 tcaatcctca acttcaacag gcggaactca ttattttaag accaagtctg ctattaaaac
    67141 tgaaccccta gttagtgcaa ctgtgattga ttactattat cctggagaga aggttcatta
    67201 tgatcaaatt ctcgaaaaag acggctacaa gtggttgagt tatactgcct ataatggaag
    67261 ctatcgttat gttcaattgg aggctgtgaa taaaaatcct ctaggtaatt ctgttctttc
    67321 ttcaacaggt ggaactcatt attttaagac caagtctgct atcaaaactg aacccctagt
    67381 tagtgcaact gtgattgatt actattatcc tggggagaag gttcattatg atcagatact
    67441 tgaaaaagac ggctacaagt ggttgagtta tacggcttat aacggaagtc gtcgctatat
    67501 acagctagag ggagtgactt cttcacaaaa ttatcagaat caatcaggaa atatctctag
    67561 ctatggatcc aataatagtt caactgtcgg ttggaagaaa ataaatggta gttggtatca
    67621 tttcaaatca aatggttcta aatcaacagg atggctgaaa gacggttcta gctggtatta
    67681 tttgaaatta tctggtgaaa tgcagacagg atggttaaag gagaatggct cgtggtatta
    67741 tctgggtagt tcaggggcaa tgaaaacagg ctggtaccag gtctctggta agtggtatta
    67801 ttcttactct tcaggcgcct tagctgttaa tacgacggtg gatggctaca gagtaaacag
    67861 tgatggagaa cgagtataga aaattggagt aggagaaatt tcctgctctt ttctgtaagc
    67921 agtttccttg acatttttct tattttgcgc tatcatatat acatataata tatgggagtc
    67981 tgtgtacagt ctgagaggaa gtgttaaact tcgaccgcac ctgatctggg taatgccagc
    68041 ggagggaacg atacttagtc taattttgca ccttttccat gtatggtaaa ggtttttctt
    68101 tttttaaaaa ggaaaacgag aagaggaggt tcttatgaaa gcaagcattg ccttgcaagt
    68161 tttaccccta gtacagggga ttgatcggat agctgttatt gatcaggtca ttgcttatct
    68221 gcaaactcaa gaagtgacga tggtagtgac accatttgaa acggtcttgg aaggggagtt
    68281 tgatgagctt atgcgcattc taaaagaagc gctggaagtg gcagggcagg aggcagacaa
    68341 tgtctttgcc aatgtcaaaa taaatgtagg agagatttta agtattgatg agaaacttga
    68401 gaagtatact gagacgacac attagtctat tgggctttct cggagtattg tcaatctggc
    68461 agttagcagg ttttcttaaa ctgctcccca agtttatcct gccgacacct cttgaaattc
    68521 tccagccctt tgttcgtgac agagaatttc tctggcacca tagctgggcg accttgagag
    68581 tggctttact ggggctgatt ttgggagttt tgattgcctg tcttatggct gtgctcatgg
    68641 atagtttgac ttggctcaat gacctgattt accctatgat ggtggtcatt cagaccattc
    68701 cgaccattgc catagctcct atcctggtct tgtggctagg ttatgggatt ttgcccaaga
    68761 ttgtcttgat tatcttaaca acaacctttc ccatcatcgt tagtattttg gacggtttta
    68821 ggcattgtga caaggatatg ctgaccttgt ttagtctgat gcgggccaag ccttggcaaa
    68881 tcctgtggca ttttaaaatc ccggttagcc tgccttactt ttatgcaggt ctgagggtca
    68941 gtgtctccta cgcctttatc acaactgtgg tatctgagtg gttgggaggt tttgaaggtc
    69001 ttggtgttta tatgattcag tctaaaaaac tgtttcagta tgataccatg tttgccatta
    69061 ttattctggt gtcgattatc agtcttttgg gtatgaagct ggtcgatatc agtgaaaaat
    69121 atgtgattaa atggaaacgt acttaaaata gagcgttttt gaaaaagaaa agaggaaatc
    69181 aaaatgaaga aaacatggaa agtgttttta acgcttgtaa cagctcttgt agctgttgtg
    69241 cttgtggcct gtggtcaagg aactgcttct aaagacaaca aagaggcaga acttaagaag
    69301 gttgacttta tcctagactg gacaccaaat accaaccaca cagggcttta tgttgccaag
    69361 gaaaaaggtt atttcaaaga agctggagtg gatgttgatt tgaaattgcc accagaagaa
    69421 agttcttctg acttggttat caacggaaag gcaccatttg cagtgtattt ccaagactac
    69481 atggctaaga aattggaaaa aggagcagga atcactgccg ttgcagctat tgttgaacac
    69541 aatacatcag gaatcatctc tcgtaaatct gataatgtaa gcagtccaaa agacttggtt
    69601 ggtaagaaat atgggacatg gaatgaccca actgaacttg ctatgttgaa aaccttggta
    69661 gaatctcaag gtggagactt tgagaaggtt gaaaaagtac caaataacga ctcaaactca
    69721 atcacaccga ttgccaatgg cgtctttgat actgcttgga tttactacgg ttgggatggt
    69781 atccttgcta aatctcaagg tgtagatgct aacttcatgt acttgaaaga ctatgtcaag
    69841 gagtttgact actattcacc agttatcatc gcaaacaacg actatctgaa agataacaaa
    69901 gaagaagctc gcaaagtcat ccaagccatc aaaaaaggct accaatatgc catggaacat
    69961 ccagaagaag ctgcagatat tctcatcaag aatgcacctg aactcaagga aaaacgtgac
    70021 tttgtcatcg aatctcaaaa atacttgtca aaagaatacg caagcgacaa ggaaaaatgg
    70081 ggtcaatttg acgcagctcg ctggaatgct ttctacaaat gggataaaga aaatggtatc
    70141 cttaaagaag acttgacaga caaaggcttc accaacgaat ttgtgaaata atgacagaaa
    70201 ttagactaga gcacgtcagt tatgcctatg gtcaggagag gattttagag gatatcaacc
    70261 tacaggtgac ttcaggcgaa gtggtttcca tcctaggccc aagtggtgtt ggaaagacca
    70321 ccctctttaa tctaatcgct gggattttag aagttcagtc agggagaatt gtccttgatg
    70381 gtgaagaaaa tcccaagggg cgcgtgagtt atatgttgca aaaggatctg ctcttggagc
    70441 acaagacggt gcttggaaat atcattctgc ccctcttgat tcaaaaggtg gataaggcag
    70501 aagctatttc ccgagcggat aaaattcttg cgaccttcca gctgacagct gtaagagaca
    70561 agtatcctca tgaacttagc ggtgggatgc gccagcgtgt agccttactc cggacctacc
    70621 tttttgggca caagctcttt ctcttagatg aggcctttag cgccttggat gagatgacaa
    70681 agatggaact ccacgcttgg tatcttgaga ttcacaagca gttgcatcta acaaccctga
    70741 tcatcacgca tagtattgag gaggccctca atatcagcga ccgcatctat atcttgaaaa
    70801 atcgccctgg gcagattgtt tcagaaatta aactagattg gtctgaagat gaggacaagg
    70861 aagtccaaaa gattgcctac aaacgtcaaa tcttggcaga attaggctta gataagtaga
    70921 aaaataggga gttggtgaag attatccttt accagcgccc tttttctttt aaaaatgaga
    70981 aaatttcggt ataatagtca aacaaggtca aggtttaaag agagaggtgg gtttgttatg
    71041 agatttaaaa atacatcgga tcatattgag gcctacatca aggcgatttt agatcaatct
    71101 ggtatcgtgg agttgcaacg gagtcagttg gcagatacct ttcaggttgt tcctagtcag
    71161 attaactacg tgatcaagac acgctttacg gaaagtagag gctacttggt tgaaagtaag
    71221 cgtggtggcg gaggctacat tcgtatagga cggattgagt tttctagtca tcatgaaatg
    71281 ctccgggagc tgctttactc gattggtgag cgagtcagtc aagaaattta tgaggatatt
    71341 ctccagcttt tggttgagca ggaattgatg accaagcagg agatgaattt gctagaatca
    71401 gtagctttgg atcgcgtttt aggagaagaa gctccagttg ttcgagcaaa catgctacgt
    71461 cagatcatac aagaggtaga tagaaaaggg aagtaagatg aactattcaa aagcattgaa
    71521 tgaatgtatc gaaagtgcct acatggttgc tggacatttt ggagctcgtt atctagagtc
    71581 ttggcacttg ttgattgcca tgtctaatca cagttatagt gtagcagggg caactttaaa
    71641 tgattatccg tatgagatgg accgtttaga agaggtggct ttggaactga ctgaaacgga
    71701 ctatagccag gatgaaactt ttacggaatt gccgttctcc cgtcgtttgc agattctttt
    71761 tgacgaagca gagtatgtag cgtcagtggt ccatgctaag gtgctaggta cagagcacgt
    71821 cctctatgcg attttgcatg atggcaatgc cttggcgact cgtatcttgg agagggctgg
    71881 tttttcttat gaagacaaga aagatcaggt caagattgct gctcttcgtc gaaatttaga
    71941 agaacgggca ggctggactc gtgaagatct caaggcttta cgccaacgcc atcgtacagt
    72001 agctgacaag caaaattcta tggccaatat gatgggcatg ccgcagactc cgagtggtgg
    72061 tctcgaggat tatacgcatg atttgacaga gcaagcgcgt tctggcaagt tagaaccagt
    72121 catcggtcgg gacaaggaaa tctcacgtat gattcaaatc ttgagccgta agactaagaa
    72181 caaccctgtc ttggttgggg atgctggtgt cgggaaaaca gctctggcgc ttggtcttgc
    72241 tcagcgtatt gccagtggtg atgtgcctgc ggaaatggct aagatgcgcg tgttagaact
    72301 tgatttgatg aatgtcgttg cagggacacg cttccgtggt gactttgaag aacgcatgaa
    72361 taatatcatc aaggatattg aagaagatgg ccaagtcatc ctctttatcg atgaactcca
    72421 caccatcatg ggttctggta gcgggattga ttcgactctg gatgcggcca atatcttgaa
    72481 accagccttg gcgcgtggaa ctttgagaac ggttggtgcc accactcagg aagaatatca
    72541 aaaacatatc gaaaaagatg cggcactttc tcgtcgtttc gctaaagtga cgattgaaga
    72601 accaagtgtg gcagatagta tgactatttt acaaggtttg aaggcgactt atgagaaaca
    72661 tcaccgtgta caaatcacag atgaagcggt tgaaacagcg gttaagatgg ctcatcgtta
    72721 tttaaccagt cgtcacttgc cagactctgc tatcgacctc ttggacgaag cagcagcaac
    72781 agtgcaaaat aaggcaaagt atgtaaaagc agacgattca gatttgagtc cagctgacaa
    72841 ggccctgatg gatggcaagt ggaaacaggc agcccagcta atcgcaaaag aagaggaagt
    72901 acctgtctac aaagacttgg tgacagagtc tgatattttg accaccttga gtcgcttgtc
    72961 aggaatccca gttcaaaaac tgactcagac tgacgctaag aaatatctaa atcttgaagc
    73021 agaactccat aaacgggtta tcggtcaaga tcaagctgtt tcaagtatta gtcgtgcgat
    73081 tcgccgtaat cagtcaggaa ttcgcagtca caagcgtccg atcggttcct ttatgttcct
    73141 aggacccaca ggtgtcggta agaccgagtt ggccaaggct ttggcagaag ttctctttga
    73201 tgacgaatca gcccttatcc gctttgatat gagtgagtat atggagaaat tcgcagccag
    73261 ccgtctaaat ggagctcctc caggctatgt gggttacgaa gaaggtgggg agttgacaga
    73321 gaaggttcgc aataaaccct attccgttct cctctttgat gaggtagaga aggctcaccc
    73381 agatatcttt aatgttctct tgcaggttct ggatgacggt gtcttgacag atagcaaggg
    73441 acgcaaggtc gatttttcaa ataccattat cattatgaca tcgaacctag gtgcgactgc
    73501 ccttcgtgat gataagactg ttggttttgg ggctaaggat attcgttttg accaggaaaa
    73561 tatggaaaaa cgcatgtttg aagaactgaa aaaagcttat agaccggaat tcatcaaccg
    73621 tattgatgag aaggtggtct tccatagcct atctagtgac catatgcagg aagtggtgaa
    73681 gattatggtc aagcctttag tggcaagttt ggctgaaaaa ggcattgact tgaaattaca
    73741 agcttcagct ctgaaattgt tagcaaatca aggatatgac ccagagatgg gagctcgccc
    73801 acttcgcaga accctgcaaa cagaagtgga ggacaagttg gcagaacttc ttcttaaggg
    73861 agatttagtg gcaggcaaca cacttaagat tggtgtcaaa gcaggccagt taaaatttga
    73921 tattgcataa aagaataaaa gtatcagcat ctgaccataa gtcacagtgg agtgaaactc
    73981 aatgaaaatc aaagagcaaa ctaggcagct agccgcaggt tgctcaaaac actggtttga
    74041 ggttgcagat agagctgacg tggtttgaag agattttcga agagtatgaa actaaaacct
    74101 atagcttcta aacgatccgt ggttttcacc attcaacaca aaattcatat gtttattacc
    74161 ctccgtcgta tttgtcttag agcgtgtgta gtagaaaaag agcagtctta tctgaaattt
    74221 ttattctttc aaaagagacc tgtttctttt ttgcatgtca aatccgttct agctggtatt
    74281 tgaaaaatca aactaatatt caatgaaaat caaagaacaa actaggaagc tagccgcagg
    74341 ttgctcaaaa cactgttttg aggttgtaga tagagctgac gtggtttgaa gagattttcg
    74401 aagagtataa gctgcaagat gaatgatttt cttgtattga cgttgttgtt gacaaaaagt
    74461 agcggataaa tgaaatccat tccattatca tagatgatag gctggtagga aattttcaaa
    74521 tagcatacag gaaatagatg tatggagttc tggtagtaga aagggagaga gatgaacatt
    74581 ttagttgcag atgacgagga aatgattaga gaaggaattg cagcatttct gacagaagag
    74641 ggttatcatg tcattatggc taaggatgga caagaggtct tggaaaaatt tcaagatctc
    74701 cctatccatc tcatggtact ggatttaatg atgcctagga agagtggttt tgaagtgtta
    74761 aaagaaatca atcaaaagca cgatattcct gtcatcgtct tgagtgctct gggagatgaa
    74821 actactcagt cacaggtatt tgatctctat gctgatgatc atgtgacaaa acctttttct
    74881 ttggtactgc ttgtcaagcg tattaaggcg cttatcagac gttactacgt catagaggat
    74941 atttggcgat atcaggatgt aacagtggat tttacctctt acaaagcaca ttataaaaat
    75001 gaagaaattg atctcaaacc aaaggaatta ctggtactaa agtgtttgat tcagcataaa
    75061 aatcaagttt taagtagaga gcagatattg gaagaaattt caaaagatgt agctgattta
    75121 ccttgtgata gggtcgttga tgtctatatt cgtactcttc gcaaaaaatt agctttagat
    75181 tgtatcgtga ctgtgaaaaa tgttgggtat aagattagct tatgataaaa aatcctaaat
    75241 tattaaccaa gtctttttta agaagttttg caattctagg tggtgttggt ctagtcattc
    75301 atatagctat ttatttgacc tttccttttt attatattca actggagggg gaaaagttta
    75361 atgagagcgc aagagtgttt acggagtatt taaagactaa gacatctgat gaaattccaa
    75421 gcttactcca gtcttattca aagtccttga ccatatctgc tcaccttaaa agagatattg
    75481 tagataagcg gctccctctt gtgcatgact tggatattaa agatggaaag ctatcaaatt
    75541 atatcgtgat gttagatatg tctgttagta cagcagatgg taaacaggta accgtgcaat
    75601 ttgttcacgg ggtggatgtc tacaaagaag caaagaatat tttgcttttg tatctcccat
    75661 atacattttt ggttacaatt gctttttcct ttgttttttc ttatttttat actaaacgct
    75721 tgctcaatcc tcttttttac atttcagaag tgactagtaa aatgcaagat ttggatgaca
    75781 atattcgttt tgatgaaagt aggaaagatg aagttggtga agttggaaaa cagattaatg
    75841 gtatgtatga gcacttgttg aaggttattc atgagttgga aagtcgtaat gagcaaattg
    75901 taaaattgca aaatcaaaag gtttcctttg tccgcggagc atcacatgag ttgaaaaccc
    75961 ctttagccag tcttagaatt atcctagaga atatgcagca taatattgga gattacaaag
    76021 atcatccaaa atatattgca aagagtataa ataagattga ccagatgagc cacttattgg
    76081 aagaagtact ggagtcttct aaattccaag agtggacaga gtgtcgtgag accttgactg
    76141 ttaagccagt tttagtagat attttatcac gttatcaaga attagctcat tcaataggtg
    76201 ttacaattga aaatcaattg acagatgcta ccagggtcgt catgagtctt agggcattgg
    76261 ataaggtttt gacaaacctg attagtaatg caattaaata ttcagataaa aatgggcgcg
    76321 taatcatatc cgagcaagat ggctatctct ctatcaaaaa tacatgtgcg cctctaagtg
    76381 accaagaact agaacattta tttgatatat tctatcattc tcaaatcgtg acagataagg
    76441 atgaaagttc cggtttgggt ctttacattg tgaataatat tttagaaagc tatcaaatgg
    76501 attatagttt tctcccttat gaacacggta tggaatttaa gattagcttg tagacagatt
    76561 agttttttat taaagttcat atagggttaa cataagtgtg ttattctttg tgtagataaa
    76621 agaaaggata ctaatatggt attagcgatt attttagtaa cattccttat tcgattgatt
    76681 tttttaaagc gttcgataga gaatgagaaa cgaatcctta gcaatggcgg gaaagaattt
    76741 ggagttgaga atacaaaacg attaactatg gctcatattg ttttttatct ctcttgcttg
    76801 gttgaggcaa tggtgcacaa gacaattttt gatggcatg
//
LOCUS       DAVLZS010000002        76180 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLZS010000002 DAVLZS010000000
VERSION     DAVLZS010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 76180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.002"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..1378)
                     /locus_tag="VYO88_000084"
     CDS             complement(<1..1378)
                     /locus_tag="VYO88_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1718265.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            1672..2595
                     /locus_tag="VYO88_000085"
     CDS             1672..2595
                     /locus_tag="VYO88_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1718266.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            2655..3260
                     /locus_tag="VYO88_000086"
     CDS             2655..3260
                     /locus_tag="VYO88_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1718267.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            3279..4523
                     /locus_tag="VYO88_000087"
     CDS             3279..4523
                     /locus_tag="VYO88_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1718268.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(4640..4897)
                     /locus_tag="VYO88_000088"
     CDS             complement(4640..4897)
                     /locus_tag="VYO88_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1718269.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(4939..6975)
                     /locus_tag="VYO88_000089"
     CDS             complement(4939..6975)
                     /locus_tag="VYO88_000089"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1718270.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(7187..8104)
                     /gene="glyQ"
                     /locus_tag="VYO88_000090"
     CDS             complement(7187..8104)
                     /gene="glyQ"
                     /locus_tag="VYO88_000090"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1718271.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(8473..9234)
                     /locus_tag="VYO88_000091"
     CDS             complement(8473..9234)
                     /locus_tag="VYO88_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1718272.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QPVIWSDFNAATQIIRESAVPTYTNNRRVVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(9507..10349)
                     /locus_tag="VYO88_000092"
     CDS             complement(9507..10349)
                     /locus_tag="VYO88_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1718273.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTTAVQSGAPRVD
                     DVDF"
     gene            complement(10464..11855)
                     /locus_tag="VYO88_000093"
     CDS             complement(10464..11855)
                     /locus_tag="VYO88_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1718274.1"
                     /translation="MDKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKSFSDQDLSAWNFDYKDS
                     QIILYPSSVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(12090..12467)
                     /locus_tag="VYO88_000094"
     CDS             complement(12090..12467)
                     /locus_tag="VYO88_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1718275.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSVQDFYTSIDV
                     LAELDNGIQVIIEIQIHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            12700..13677
                     /locus_tag="VYO88_000095"
     CDS             12700..13677
                     /locus_tag="VYO88_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1718276.1"
                     /translation="MLKLGIIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            13674..14756
                     /locus_tag="VYO88_000096"
     CDS             13674..14756
                     /locus_tag="VYO88_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1718277.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYISATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDINVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(14820..15866)
                     /locus_tag="VYO88_000097"
                     /pseudo
     CDS             complement(14820..15866)
                     /locus_tag="VYO88_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(16250..17446)
                     /gene="tuf"
                     /locus_tag="VYO88_000098"
     CDS             complement(16250..17446)
                     /gene="tuf"
                     /locus_tag="VYO88_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1718278.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(18357..19226)
                     /locus_tag="VYO88_000099"
     CDS             complement(18357..19226)
                     /locus_tag="VYO88_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1718279.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKATEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(19450..20058)
                     /locus_tag="VYO88_000100"
     CDS             complement(19450..20058)
                     /locus_tag="VYO88_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1718280.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            complement(20016..21122)
                     /locus_tag="VYO88_000101"
     CDS             complement(20016..21122)
                     /locus_tag="VYO88_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1718281.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDILLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(21233..21487)
                     /locus_tag="VYO88_000102"
     CDS             complement(21233..21487)
                     /locus_tag="VYO88_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718282.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(21827..22273)
                     /locus_tag="VYO88_000103"
     CDS             complement(21827..22273)
                     /locus_tag="VYO88_000103"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1718283.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDVLREVPTIFECLECFFKTR"
     gene            complement(22346..22671)
                     /locus_tag="VYO88_000104"
                     /pseudo
     CDS             complement(22346..22671)
                     /locus_tag="VYO88_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            22905..24623
                     /locus_tag="VYO88_000105"
     CDS             22905..24623
                     /locus_tag="VYO88_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1718284.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            24734..25081
                     /locus_tag="VYO88_000106"
     CDS             24734..25081
                     /locus_tag="VYO88_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1718285.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(25360..26196)
                     /locus_tag="VYO88_000107"
     CDS             complement(25360..26196)
                     /locus_tag="VYO88_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1718286.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(26209..26838)
                     /locus_tag="VYO88_000108"
     CDS             complement(26209..26838)
                     /locus_tag="VYO88_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1718287.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(26848..27489)
                     /locus_tag="VYO88_000109"
     CDS             complement(26848..27489)
                     /locus_tag="VYO88_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1718288.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(27635..28864)
                     /locus_tag="VYO88_000110"
     CDS             complement(27635..28864)
                     /locus_tag="VYO88_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1718289.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(28854..30020)
                     /locus_tag="VYO88_000111"
     CDS             complement(28854..30020)
                     /locus_tag="VYO88_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1718290.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            30164..31177
                     /locus_tag="VYO88_000112"
     CDS             30164..31177
                     /locus_tag="VYO88_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1718291.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(31222..31641)
                     /locus_tag="VYO88_000113"
     CDS             complement(31222..31641)
                     /locus_tag="VYO88_000113"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1718292.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(31652..33058)
                     /gene="atpD"
                     /locus_tag="VYO88_000114"
     CDS             complement(31652..33058)
                     /gene="atpD"
                     /locus_tag="VYO88_000114"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1718293.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(33144..34022)
                     /locus_tag="VYO88_000115"
     CDS             complement(33144..34022)
                     /locus_tag="VYO88_000115"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1718294.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(34038..35543)
                     /locus_tag="VYO88_000116"
     CDS             complement(34038..35543)
                     /locus_tag="VYO88_000116"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1718295.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(35558..36094)
                     /locus_tag="VYO88_000117"
     CDS             complement(35558..36094)
                     /locus_tag="VYO88_000117"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1718296.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(36094..36588)
                     /gene="atpF"
                     /locus_tag="VYO88_000118"
     CDS             complement(36094..36588)
                     /gene="atpF"
                     /locus_tag="VYO88_000118"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1718297.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(36602..37318)
                     /gene="atpB"
                     /locus_tag="VYO88_000119"
     CDS             complement(36602..37318)
                     /gene="atpB"
                     /locus_tag="VYO88_000119"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1718298.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(37353..37553)
                     /locus_tag="VYO88_000120"
     CDS             complement(37353..37553)
                     /locus_tag="VYO88_000120"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1718299.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(37628..38560)
                     /locus_tag="VYO88_000121"
                     /pseudo
     CDS             complement(37628..38560)
                     /locus_tag="VYO88_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(39012..39410)
                     /locus_tag="VYO88_000122"
     CDS             complement(39012..39410)
                     /locus_tag="VYO88_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1718300.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(39738..40220)
                     /gene="greA"
                     /locus_tag="VYO88_000123"
     CDS             complement(39738..40220)
                     /gene="greA"
                     /locus_tag="VYO88_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1718301.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(40291..41946)
                     /gene="mltG"
                     /locus_tag="VYO88_000124"
     CDS             complement(40291..41946)
                     /gene="mltG"
                     /locus_tag="VYO88_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1718302.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(42027..42521)
                     /locus_tag="VYO88_000125"
     CDS             complement(42027..42521)
                     /locus_tag="VYO88_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1718303.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(42518..42982)
                     /locus_tag="VYO88_000126"
     CDS             complement(42518..42982)
                     /locus_tag="VYO88_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1718304.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(42992..44326)
                     /locus_tag="VYO88_000127"
     CDS             complement(42992..44326)
                     /locus_tag="VYO88_000127"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1718305.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDT
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(44337..44954)
                     /locus_tag="VYO88_000128"
     CDS             complement(44337..44954)
                     /locus_tag="VYO88_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1718306.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTAPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(45002..48100)
                     /locus_tag="VYO88_000129"
     CDS             complement(45002..48100)
                     /locus_tag="VYO88_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1718307.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIVQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADNHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(48193..49359)
                     /locus_tag="VYO88_000130"
     CDS             complement(48193..49359)
                     /locus_tag="VYO88_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1718308.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            complement(49367..50461)
                     /locus_tag="VYO88_000131"
     CDS             complement(49367..50461)
                     /locus_tag="VYO88_000131"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1718309.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(50619..52301)
                     /locus_tag="VYO88_000132"
     CDS             complement(50619..52301)
                     /locus_tag="VYO88_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718310.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKYFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTIYSSSKGSSVALENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENR
                     PVLKDITCSIFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKE
                     WRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDT
                     EVGERGRLLSGGRSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEK
                     TVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            complement(52473..54431)
                     /locus_tag="VYO88_000133"
     CDS             complement(52473..54431)
                     /locus_tag="VYO88_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1718311.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(54634..56256)
                     /locus_tag="VYO88_000134"
     CDS             complement(54634..56256)
                     /locus_tag="VYO88_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1718312.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            56362..57807
                     /locus_tag="VYO88_000135"
     CDS             56362..57807
                     /locus_tag="VYO88_000135"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1718313.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(57850..58047)
                     /locus_tag="VYO88_000136"
     CDS             complement(57850..58047)
                     /locus_tag="VYO88_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1718314.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(58148..58756)
                     /locus_tag="VYO88_000137"
     CDS             complement(58148..58756)
                     /locus_tag="VYO88_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV1718315.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            complement(58781..59293)
                     /locus_tag="VYO88_000138"
     CDS             complement(58781..59293)
                     /locus_tag="VYO88_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1718316.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(59380..60315)
                     /locus_tag="VYO88_000139"
     CDS             complement(59380..60315)
                     /locus_tag="VYO88_000139"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1718317.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(60386..60685)
                     /locus_tag="VYO88_000140"
     CDS             complement(60386..60685)
                     /locus_tag="VYO88_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1718318.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(60675..61424)
                     /locus_tag="VYO88_000141"
     CDS             complement(60675..61424)
                     /locus_tag="VYO88_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1718319.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(61478..61837)
                     /locus_tag="VYO88_000142"
     CDS             complement(61478..61837)
                     /locus_tag="VYO88_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1718320.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(61839..63239)
                     /locus_tag="VYO88_000143"
     CDS             complement(61839..63239)
                     /locus_tag="VYO88_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1718321.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(63534..63773)
                     /locus_tag="VYO88_000144"
     CDS             complement(63534..63773)
                     /locus_tag="VYO88_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1718322.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(63805..64275)
                     /gene="ssbA"
                     /locus_tag="VYO88_000145"
     CDS             complement(63805..64275)
                     /gene="ssbA"
                     /locus_tag="VYO88_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1718323.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(64287..64577)
                     /locus_tag="VYO88_000146"
     CDS             complement(64287..64577)
                     /locus_tag="VYO88_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1718324.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(64730..66076)
                     /gene="asnS"
                     /locus_tag="VYO88_000147"
     CDS             complement(64730..66076)
                     /gene="asnS"
                     /locus_tag="VYO88_000147"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1718325.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(66092..66457)
                     /locus_tag="VYO88_000148"
     CDS             complement(66092..66457)
                     /locus_tag="VYO88_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1718326.1"
                     /translation="MIDHFEIKVKDLQILEGFYRSFLVPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGIEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(66450..67637)
                     /locus_tag="VYO88_000149"
     CDS             complement(66450..67637)
                     /locus_tag="VYO88_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1718327.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYSFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(67634..68122)
                     /locus_tag="VYO88_000150"
     CDS             complement(67634..68122)
                     /locus_tag="VYO88_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1718328.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            68443..68991
                     /locus_tag="VYO88_000151"
     CDS             68443..68991
                     /locus_tag="VYO88_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1718329.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            complement(69228..76157)
                     /locus_tag="VYO88_000152"
     CDS             complement(69228..76157)
                     /locus_tag="VYO88_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1718330.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIIGLELRSNSNKGTVSETPVAKKADTTEAKEEAKPAAR
                     TTDRSAVDSSVLATNAPAKVETTSAPKSTNEILKPGLNLSDARQNPAIRKEDVDRGYS
                     GFRTAGSGFRAAGSGFRAAGPENKPILNPNNTIAFSDISQGSHSFRGIGHSRGGREIH
                     YDVTTVRRGDNIEFTINYSAPGNLREFVNNNFILDKGDGFGNPSNATITSSNPRVREQ
                     SKSISQGANYVSHSGYSMTSAISTNTEQTIRFSLPIINLNGDLSVRLKPVTFNVDQGG
                     GGAATSNDPYSNSNYYYRANPLYLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQT
                     RLVREGEKGQRQITYKVHRFGNETLLGLPISNSVTKEAKPRIMQIGVAKDLIDTVKPR
                     VDQNKVGDTNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAKG
                     EKGDRGERGLTGAQGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTGAQGAKGEKGD
                     RGERGLTGAKGEKGDRGERGLTGAQGAKGEKGAQGERGLTGAKGEKGDQGERGLTGAQ
                     GEKGDRGERGLTGAKGEKGAQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTST
                     VVRDGFDGASPLVATQRNDADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEK
                     GDKGEQGLQGRDGEQGPKGEDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFD
                     GASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNG
                     KDGFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTT
                     LTFYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDG
                     DTFVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGE
                     KGDQGERGLTGSKGEKGDQGERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPA
                     GPQGPKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGR
                     NGTNGQSPTITATRSVQNGKNGVLVTITPVEGRPQTTFVEDGQKGADGKTPTVTITEG
                     QNGTHTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTE
                     TGDVYVKNNGNWDKEGNIKGPKGDKGAQGAKGEKGAQGERGLTGAQGAKGADGAVGRD
                     GRDGKDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERG
                     EDGKTPEVTVTPGKDGHSTDITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKN
                     GNPSHTIVTFYTDENNDGKYTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETK
                     VYQEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQP
                     TTVFVQDGAKGETGATGQDGQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNG
                     KDGRAPKIKVEDITSPSRIRRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNS
                     KDIYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTE
                     NPDGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAI
                     IKDGKDGKAATATTTENPDGSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNG
                     DGSHTIVITNPEGVTTETTVRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGR
                     EPKLEVIDNNDGSHTIKVTGADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGR
                     EYKSIIKDGKDGKDSVSPTVTVKNNNYGTHVVTITNPDGSKTEMVIKDGKDGKSPKVS
                     VEDNGDGSHTITIINSDGTVTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPS
                     NDKPVPPTPNVPTPEVPVKPVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQ
                     PVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRR
                     KEA"
BASE COUNT        21729 a        16815 c        13973 g        23663 t
ORIGIN      
        1 atttttcagc cgtaagggca gccattgtga tgtagttgta tggtttgttg aagtgtggca
       61 agaagaagag gtctgtcaat gccaatttat caattgtcac atgctcttgg atagcaagtg
      121 agaacatgtg gattcccatg ctaattgcaa tatcatgtga aaccatttgg gcaccaagaa
      181 tttcacggct atctttgtca aagacaatct taattgctac ttcatggttg tcatgtttca
      241 tgaattctgg tttttgaaga tcgttaaagc ctgtttcagt tgcgttgtaa ccagcagctt
      301 tcgctttttc aagagtcaaa ccagttgaaa ccatgtgaag accgtagatt gagataccat
      361 ttgaaccttg aacaccgatt ccttccaatt catgtccaca agcattgtag gcaccaacga
      421 taccagtgcg aacagcattt gaagcaagag cgatatagct tgtatcttta cgagcattgt
      481 cataaacagt cgcacagtca ccaacagcgt aaacgcctgg gatagatgtt tcttgtttct
      541 tgtctacaag gaaggcaccg ttgcgaaaga gttcgatctt accatctgca agggctgtgt
      601 ttggacggaa accaactgca aggataacca tatccacgtc aaagctttct ttgtcagtaa
      661 tcaagcgttc aactttaccg tcaccttcga ttgctttaac agtttgacct agagccaagc
      721 ggatgttgtg atcttccaag ttcttcgcca tcatttgtgt gaagtctttg tcatagtaac
      781 cgttcaagac agtatcaacg atatcaacaa gaacaacttc ttttccaaga cgttcaaagg
      841 cttcagcaag ttcaacaccg atgtaaccac caccaacaac ggcgatacgg tcgaggtgtt
      901 ggctcttgtc agaaagttta ttgataactt cttcagcatt ttggtacaat ttcacgaatt
      961 gtacgttttc aagagttgct ttaaattcgc ggtttccttt aacaatttca acaccttcga
     1021 ttggtggcaa gattggtgta gaacctgtag cgaaaatcaa tttttcgtat gattctttgt
     1081 gctcttttcc ttcaacttcc gctgtaacta ctttgttatc atagtcgatt gaaagaacag
     1141 gtgagttcat gtaaacttta gcacctttag cttccaattt ttctttatca gaatagaaca
     1201 agccttcagc accgtcaatt tgttcaccaa tccaaagagc cattccacat cctaggaaag
     1261 agatgttaga gttttggtca aatacaacaa tttcgttctc atttccaaaa ttatccaaca
     1321 tggtattgat acatgctgta ccagcgtggt tagcaccgac tacaacgatt ttactcataa
     1381 aaatttcctg ccttcattct aaatttacct tactagtata ccatttaccg ttagcgttta
     1441 caaggggggt actattattt cagcattttt tatcaaaaat aattccccat ttatcctgtt
     1501 ttcaagcctc atgaatttta tgagcatatt tcttgacttt ttccaaattt tgtttgtgaa
     1561 aattctaact ttatggtatt ataataacat gaaaatgaaa tgtaagggct tcaatttaga
     1621 tgattatttg atattacaac ttattttcta taagagaaag gagttggtag cttgactctt
     1681 cgttcacatt ctgaacggct aatggggact actatcacta tttcattagt ggatgagcaa
     1741 gccgatatct ttctccaaaa atcctttgac ttgctcaaag aacttgaata ccgcttcaac
     1801 gccaatagtc aagaatctga gttgatggaa atcaattatc aagcaggaat agcccccgtc
     1861 acggttcatc cagacctgtt tgagttgatt tcacttgggt tagagcatag cctagcgctc
     1921 tctagccacc tcaatatcag cattggtccc ttaattcaaa cctggcgtat cggtttttca
     1981 gatgccaagg tcgcccagcc tcaagaaatt gaatcggtgc tgcctctaat caatcctcat
     2041 ggtatcgagt tagattcttc tacttctact gtgtttttaa aacagaaagg aatgaagatc
     2101 gatctaggtt gtttagccaa aggatacagt gcggataagg ttgcccaatt tcttaggaaa
     2161 gagggggtga cttctgcctt gatcaatctg ggagggaata tcctgaccat tggaaaaaat
     2221 caggcaagag gggataaccc atggcaaatc gggattcaag acccagccaa tcctagggga
     2281 aatcatttaa tgaccatccc tgttgtcaat aaatctgtcg tgacttcagg catttatgaa
     2341 cgtcacctga ccgtcgatgg acaagattac catcacattt ttgacagtca aacaggatat
     2401 cctgttgaaa cggaactagc gagtctaaca atcatctctg ataaatcagt cgatggcgaa
     2461 atctggacga ctcgactctt tggagaaaga cctgcttcta tcctctggca agtcgaaagt
     2521 ttggagggca tcgaagtcat cctcatcgat aaagaaggcc acctaagctg ttcttcagga
     2581 attcctactc tatagagaca actgtttcaa tggaatttta aaattgtatt atgtaaaaag
     2641 agaaaggaaa tctcatgtta aaacttattg ctattgttgg aacaaattca aaacgttcta
     2701 caaaccgtca attgcttcaa tacatgcaaa aacactttac tgacaaagct gaaattgaac
     2761 ttgttgaaat caaggccatt cctgtcttca acaaaccagc tgacaagcaa gtacctgctg
     2821 aaatattgga aattgctgct aaaatcgaag aggcagatgg cgttattatc ggtactcctg
     2881 agtatgatca ctctattcca gctgttttga tgagcgctct tgcttggttg tcttatggta
     2941 tttacccact tttgaacaaa ccaatcatga ttacaggtgc ttcttacggt acgcttggtt
     3001 catctcgtgc ccaattgcaa cttcgtcaaa tcttgaatgc tcctgaaatc aaggcaaatg
     3061 ttcttccaga tgaattcttg ctctcacact ctcttcaagc atttaaccca agtggcgact
     3121 tggttgacct tgatgttatc aagaaattgg atgccatctt tgatgacttc cgtatctttg
     3181 taaaaatcac agaaaaatta cgtaatgcac aagaattact tcgcaaagat gctgaagact
     3241 ttgactggga aaatttgtaa gataggagac caaaaagaat gaaatttgtt ggacttgttg
     3301 gatcaaacta cgatcaatca tataaccgta agctcttgga atttatccgt cgctacttca
     3361 aactcaaatt tgaattagaa gttcttgaaa ttgacgaagt tccaatgttt aaccaagatg
     3421 aaaaatggga tgaaagtttc caattacgtt atttatataa caaaattact cgtgcagatg
     3481 gtgttatcat tgctactcct gagcataacc acactatctc agcttcactc aaatctgtac
     3541 ttgaatggct ttcatacgaa gttcatccat ttgaaaacaa gcctgttatg attgtgggtg
     3601 catcatacta tgaccaagga acatcacgtg ctcaagttca ccttcgtaaa atccttgatg
     3661 ctccaggtgt taatgcctac acgcttccag gtaacgaatt ccttcttggt aaagctaagg
     3721 aagcttttga taacaacgga aatatcacca acgaaggcac tgttaaattc cttgaaactt
     3781 gcttagataa ctttgttaaa tacgtaggag tcgtttcgaa attgaaaaaa ccaaaaccaa
     3841 tcgaatcaga agacttggat tgtggaaaac caatcgctac aaccatcaca gaagttgacc
     3901 ctgacgatcc agaatgggta gaaaaagttg cagcaatcac tggtgctgtt tctggtgata
     3961 cctatgtcaa attggaccac ggtatcctaa cagttaacca aattgatatg ttcttgaaag
     4021 ctatgccatt tgaattgaca tacgctgacg acaacaacca attcctctac tacaacaacg
     4081 ctcaccaaga tccagacact atgttcgcta aacgtgtacc acctcaatca ggtagccgta
     4141 tgtcgactgt tcatggttct cttccaccag cacgtatgaa gaacgtagag tgggttatcg
     4201 gaacacttcg caacggaaac caagaatacg tccgtacgat cgttccaggt tctcctgcag
     4261 gtgttatcaa cactcacaac taccaagcaa tgtactatcc tgatggatca tacgctggta
     4321 tcaatgaaat cgtctttaac ttccaaccat ggcttgactg gtacctaaaa gagactggtc
     4381 aacgtttggt gggtggtagc ggaccatttg ctcctgctgc cggaggtcat ggagacgccg
     4441 atgctacttc tggcgcttct gattcagggg atgctggagg ccacggtggt gacgcagacg
     4501 ctacagccgg tgcaagttac taatgatagt ttttaggaac cattatggtt ccttttttag
     4561 cgaaaaaaga ctagcaaaca caaactgcta gtctttttgt tatcgtttca tctatctttg
     4621 ttaaaagaaa gagtacatat tatgaatttg ggtcatcaag actacggcca tgtaatcctt
     4681 tttcacgttg tacttggcgt agtttttctg gtgtaacatc gtttccttct tcgtccacaa
     4741 ttttgattcc ttcaatgtgg tgacgaacag cgcggcgata accttcgatg tactcctcac
     4801 gtagtttggc ttgttccact ttttcttctg atgttaagcc ttctgttttt ttctttttag
     4861 caagctcatt gatacgagca atttttttcg gatccatttc ttctcctttg taataagata
     4921 aagtccgttt atcaaatttt atttagtgtt aatttggtta aaacaagcaa acttagctgc
     4981 tttcttggtt agttgtgaca agattgccaa acgattttga cggacagcct gatcttcagc
     5041 cattaccata gtattttcaa agaaagcatc aatgactggg ctaagcgcaa agagttgttt
     5101 caattgctga cttgcaggtc ctgataaaac gagtgtttct actgcttctg ccaaagcttt
     5161 ttcttggtca ttctcaaata gtgctgaatc aactgtagca accccttctg ccttctcagc
     5221 caggttaaag gcacgagaaa gtgattcaac agatggttta aaatcttctt ccttgcttac
     5281 ttctacgaga gcacttgctg cttccaacat atctgccaca acaaagtttg aacctgcaag
     5341 aactgcttcc ttgatatctt ttggagtaga gcccatcatc ttatcaacac gagccttgat
     5401 aaagtccata acctctgctt tattttcata agtcaaactg tcaaatttca atgcataaag
     5461 gctatcaatc agctcatcca tagcaatgtg ccaaccaaag gcatccaaga tacgaaccac
     5521 accttgagtt gcacgacgaa gggcataagg gtcattagaa cctgatggaa tcaatcctac
     5581 tgagaagaaa ctcaaaatcg tatccaattt gtctgcaatg gctagaactg cgccgacctt
     5641 gctctctgga agttctcctt cagctgatgt aggcatgtag tgttcacgaa tagcagctgc
     5701 caccgctgga gtttcaccag caagaagggt gtatttttca cccataattc cttggagttc
     5761 gtcaaattca ccaaccatac ctgtcaacaa gtcaaacttg taaatggctg ctgcacgagc
     5821 aaggtcaact gtttcatcca ctgacaaacc agctttttct gccaaaagta cagtgatttg
     5881 acccgtacga atcatgtgtt cacgaaggga accaatcttc tcatggaagg tgacattgtt
     5941 taatttttca acaagatctg aaatcaccaa tttttggtct tcacgccaga agaattctcc
     6001 gtcttccaag cgggctacca agactttttc atttcctttg atgacatttt tcaaacgctc
     6061 tgcgtttccg ttacgaacag aaatgaagtt tggcaagagt tttccatctt gatcacgaac
     6121 aacaaagtaa cgctggtgtt ccttcataga agtcaccaag acttcttctg gaacttcaag
     6181 gtatttagca tcaaaacttc ccatgaaggc agttgggtat tcaaccaaat tcaagacttc
     6241 attcagcaaa tccgcatcaa tttcgatacg tacaccatgt tttgcctcaa tttccttgat
     6301 ttggtcaaca atcatttgct cacgttcaca tggatctgcg attacaaact gcttacgaag
     6361 gtcttcttca tagctcaatg ctgactgaat tttggtttct ttccccaaga aacgatggcc
     6421 acggctcaca cgacttccct tgatatcaag gaaatccaag tcaaactctt gctcatccaa
     6481 gagaacagtt aaagtgtgaa cagggcggat gtattcaaag ctatttccag cccagtgcat
     6541 gctgacaggg aaagtcaatg acttcaagac atctacaaca ccaggaacaa tggcttcaac
     6601 tgcttgacca acttcttcct tagtgacata gacatattct tcacccttga tttcacggaa
     6661 ttcgatatct tcaacagtca aacctttccc acggacaaat ccttgagctg ctttggtgaa
     6721 gtttccatca ctatccaagg caattttctt tgctggtccc ttgaaatctt ctgtcaaatc
     6781 agactgtttg tctgataaac cagtcacacg aacagccaaa cgacgtggtg ttgagaaggt
     6841 ttgaatggct tcaaaagaca ggcggttttc cttgaggaag gctgccattt tttcgcctag
     6901 ttgtttttca cttggtgtga caacataggc tggtaattct tcaagaccga gttctactaa
     6961 taagtttttt gtcatgtttt ttctccgaaa agtatctttt tattttccag tttgccttat
     7021 gtgattggca cgcaagcaac caacttcgtt gtttcattgc taaaattgga gccaaaagtc
     7081 tccaattttg cctagtatcc ttagtttcac taaggatacc ttcatcactg cggcaactgg
     7141 ctcagggctc actctgttcg cccattttcg taatttgtca ctctctttat tctgcgtctt
     7201 ctgctaggag tttagctctt gtttcttcat ccaaaagtgg gtagcctagg cgtttgcgtt
     7261 ctgcgacaaa ggttttggct acgacacggg ccaagttacg gatacgagcg atatagcctg
     7321 cacgctctgt tacagatacg gcaccacgcg cgtcaagcag attaaaggta tgtgaacatt
     7381 tgagaacata gtcataggca gggtgtacca agccttcttc taatgcacga ccagcttctt
     7441 tttcaaactt atcaaagttt tcaagcaaca tttcttggtc cgaaatttca aatgaatatt
     7501 ttgagtgctc atactcaggc tggataaaga tttctccgta ttttacacca tcagcccact
     7561 cgatatcata gacagagtct acttcttgaa tgtaagaagc caagcgctcc aaaccatagg
     7621 taacttccgc agtcacaggg ctagttgcca atccaccgac ttgttggaaa taagtgaact
     7681 gagtgatttc cattccgtca agccaaactt cccaaccaag accagctgaa ccagttgatg
     7741 ggttttccca gttgtcctca acaaaacgaa tatcgtgctc caaaggattg attcccaatt
     7801 tttccaaaga ctcaaggtaa agttcttgga tatttgatgg agaaggcttc atgaccacct
     7861 ggaattggtg gtgttggtag agacggttag ggttttcccc ataacgaccg tcagcaggac
     7921 gacgtgatgg ctctacataa gctgcattcc atggctcagg tccgatagca cgaaggaaag
     7981 tgtaaggact cattgttccc gcaccttttt cattatcata agcctgcata agcatacaac
     8041 cttggtcatt ccaaaattgt tgcaaagtaa ggatgatttc ctggaaagtc aatttcttag
     8101 acattgttta ctccttttta tataaattac ttgcgacatg agtctgcctc gtcgatcata
     8161 cgaggcaaga cgagttagta ctgcgtctag ctcaggcact ctagtgctga gcgtggggca
     8221 gtcctactgt aaggaggttt ctgccactga tgcagtaaaa tgttaatttc tcagacattg
     8281 aatactcctt aataaaaaat aatttcttgc gacacgagtc tgcctcgtcg attatacgag
     8341 gcaagacgag ttagtactgc gtctagctca ggcactctag tgctgagcgt ggggcagtcc
     8401 gactgtaagg aggtttctgc cactgatgca gtgaaatgtt aatttctcag acattgaata
     8461 ctcctttagt ttttatattt ctttttcaat taatttctgc tgaacaaacc aatctaacaa
     8521 gggaaaagtt ttttctgtat ttgcccataa atgataagaa tcaaagaccg cttgtacact
     8581 acctaaattt tctaccaact tatctactgt caaaaagctg cgccagtatt cataaaaaat
     8641 acttgcatag ttcttatcat aagtcgaaga accaaaatca ttcaatgaat gccaaccata
     8701 cttcttctga aaaagttcta cgagagattg attacaaatt ttttccgctt gaaattcctc
     8761 ttctgtcaag aaatacttgc gactaatata ttcaaccatc ccctcttcga accagatata
     8821 agagtcataa ccatcaaaat catctaaaaa atgctccgac caatgagcta actcatgtcc
     8881 tacaatctgt aagaggaaat tttcagataa agaatgatag tggctttcta ttgcttgagt
     8941 ttgctcagaa cactcgtagt ccatcaactg atacaaatac aactctttcc aaacagctaa
     9001 atcaggcgtc ataaccactc gtctattatt tgtataggtt ggaacagcac tttccctaat
     9061 aatctgtgta gcagcattaa aatctgacca aataacgggt tgcggtaaat cacagactgc
     9121 aagttcattc tttaaaaaag attgataatc tttcaacttt tcagtatttc ttactacaaa
     9181 atcacgaaat gtagctagtt gactatcgtc ttttacaaga taaaggttgt ccacggctct
     9241 cctttctttc acacaataga ctgaataagc aaaagaacca catctgacaa tcctaggttg
     9301 atttaaccta ggggcgtcag aaacgcggtt ccaccctaat ttattacttc attgtttttg
     9361 aaaatactac agaaagcgcc agctcattat tttgccctac ttggctccca ctgtcccaag
     9421 ctcgcttgaa gaacgccata agactttctt tcctgctgac tattatatca aaaattagaa
     9481 taatgtacaa ttctttttat gattttctag aaatccacat catcaactcg tggagccccc
     9541 gactgaacag cagtcgtttt taaggtttct ctctcctcat gactcagttc aattccaaaa
     9601 caatcaagat tagcttgaat acgagaggtt gtgacagatt ttggaagtgg taaaaatcct
     9661 tctgccaagc tccaggccaa ggctatctga gcaaccgatt ttccgtgatt tgctgctatt
     9721 tcttggactt gcttgctatc aaacagttct ccttgtccaa aaggccccca agcttccaat
     9781 aaaattccct tttcacgaca gtaagctacg acttcctctt gatacacacc tggcgccaag
     9841 cgaacttgat tgaccgcagg aacgatagtt gcagtttcaa gcaaggcatc caaatgatgg
     9901 ggaagaaaat tgctaacgcc gatagcacgg attttccctt cttgatagag gtcttccatc
     9961 gctctccaaa cttccgcatt gcgagttttc catgcgtcat tttctctgag cggttttggg
    10021 ttcggccaat gaatcaaata caaatccaaa taatccaagc ccagtttttc tatagatttt
    10081 tccaaagctt gacgagtttg ctcataggtt tgctgactat tccaaagctt ggtagttacg
    10141 aacatttctt cacgtggaac tccgctatct ttgattgctt gaccaacact ttcttcattc
    10201 tgataaatcg ccgccgtatc aatatgacga taaccagcct tcaaggcttc taacactgca
    10261 cgataggctt cttctccatc cttagcctta aaagttccaa atcccaatac tggaatttct
    10321 actccattat ttaattgata ggtattcata tgcttctcct tctatattta ttcatcaatt
    10381 atagcataaa acatttttta agtagtacta tcttctgtaa aaaataagtc tgtcaaatat
    10441 ctaacagacc tattttttct tgcttattca tcacgactat agtacagctc atgagctttt
    10501 aggcgagtat tgagcatctc tggtatggtc acaaaggtat aaccttgatt tttcaaatac
    10561 tcaatgaccc ttggcaaggc attgactgtc ggactgtgaa tatcatgcat caaaacgata
    10621 gagccgttag ctacttgatg ctgaatttct gtcaaaatag atgcttcatt tttactcttc
    10681 cagtccagac tatccacatc ccacatgata aagctcaaat ccaagctatt gcgaatatca
    10741 tctgtaatag caccataagg tggacgcatg agtttagaac tagaacccag cactttagtt
    10801 agcacatcct cagtatcagt aatctgcttt ttagcttcat caagagagag ttgcgagaga
    10861 atcggatggc tccaactatg gtttccaaca acatgacctt cagattttat cctcttcacc
    10921 aagtcctcat tcccagaaac atttttccca agcacaaaga aagtcgcttt aatatcatat
    10981 ttagctaggg tctctaatac ctgcggggtc gttgctggat ttggaccatc atcgaaggtt
    11041 agagcgacaa ctttttgata tttcttatca aagtaagatt ggtacaaggc cgcatctttt
    11101 tcgagtaagt acgaagattg gataacatca aagaaagcag atactggcaa ggctatctct
    11161 tctaaatttt caaccacaga acttggataa aggataatct gactatcctt gtaatcaaaa
    11221 ttccatgcag acaagtcttg gtcagagaag ctttttacaa tctgctcact ctggtcttgc
    11281 tctatttttt tatcctctat gaaggaggtc aactctttta tcagctgttc cttagcctta
    11341 ctagcatctg aaaacagttg gtcaagtgta aaaggttgcc catcttctgt taagtgaacc
    11401 tttcctagac tggtcttttc agtctcttca atcttaaaag caactaaatc atagatttgt
    11461 ttggtcacat tacgattaac gactcccttt aaacctgact cttcttgctc tgtatagtag
    11521 aaaacaagat tgtccttact ttctagcttg tccttaacat cttgatttat cagctcccta
    11581 acagaggaaa tcactttctc cccttggaga ggataatagg caatcacttc ggcttgcccc
    11641 tgacgaaaat gctccttctg atttccctca ctcaattgat catctttctc ttttttgagc
    11701 gattcaatct tttgctcaaa acttttttgc tggtagatct taaaagcaat aaatccgcct
    11761 aataggcaaa tagaaattgc taaaatacca atcaaagcca ataatacatg tctcgttttc
    11821 ccgtgtctgc cacgtcccag tctactttta tccatattta tatcataaca aatttgagca
    11881 ataatttcaa tgatacaatt tggcaatcca caattcctct agcaagccaa agcatcttac
    11941 atcaactcca acatccgtat ctgtagagat tatgtagttt tctatctatg gaatttctag
    12001 tagattgaag ctagaatagt agacctatac ttctaaaaca ttgttagaaa tcgattttac
    12061 tgtcctgatc gatttgtcct attctcattt cattttacta taaaactatg aaaagctagg
    12121 tcatctgaga agtaattact atcgacaatt gcgatagcgt atactggtgc gatttgtttg
    12181 tagctctggt gggtatcacc ttcacgttgg cgaatttttt ctaggttttg attaacctga
    12241 ctgcacagat aagcccatag gcgattgatg aaaaaattct gatgatgaat ctgaatttcg
    12301 atgataactt ggattccatt atctaactcc gccaagacgt ctatactagt atagaaatcc
    12361 tgcactgagt agggcatgga aggcaagacg tgaatgttac ttccctccaa aatcgtcaca
    12421 ttttttgctg gcaagtccag catatcgcgg ataaattgac aaatcattag tttggctgat
    12481 acccggatgt ctgagaatcc tccttttcct ccttctatta tagcacattt ttaaatctag
    12541 gtttgctaga ttctatgctt ctatctattt attcggaaaa gaaagctttt cttcagaaga
    12601 aagctaatag cttatttgaa attttctcct ctctgttgga tagtcccgtc tatctatgtt
    12661 ataatgaaag aaggatttaa aatcggaaaa ggagtattta tgctaaaatt aggtatcatc
    12721 ggaactggcg ctatcagcca tcatttcata gaagcagccc ataccagtgg agaataccaa
    12781 ctggtcgcaa tctattctag aaaactagaa actgcagcaa cctttgcttc tcgctatcaa
    12841 aatatccaac tattcgatca attagaagtc ttcttcaaat cttcttttga tttagtctat
    12901 atcgccagtc caaactcctt acattttgct caggcaaaag ctgccttgtc tgctggtaaa
    12961 catgttattc tcgaaaagcc agctgtcact caaccacaag aatggtttga tttgattcaa
    13021 acagctgaaa aaaataactg ttttatcttt gaagcagctc gtaattacca cgagaaagcc
    13081 tttactacta tcaaaaactt tttagcagat aagcaagtgt taggagcaga tttcaactat
    13141 gccaaatact cttccaagat gcctgacttg ttgactggac aaacaccaaa tgtcttttca
    13201 gaccgttttg ctggtggagc cctcatggat ttggggattt atcccctcta tgctgctgtt
    13261 cgtctttttg gaaaagccaa tgacgcgact taccatgctc aacagcttga caatagcatt
    13321 gacctaaatg gagatggtat cctcttctac ccagactatc aagttcacat caaggctgga
    13381 aaaaacatca cttccaatct tccttgcgag atttatacaa cagatggaac cttgactctc
    13441 aacacgattg agcatattcg ctcagctatt tttaccgacc accaaggaaa tcaagtccag
    13501 cttcctatcc aacaggctcc tcatacgatg actgaggaag tcgctgcatt tgcacacatg
    13561 atccagcaac cagatctgaa tctctaccaa acttggctgt atgatgcagg ctctgttcat
    13621 gagctactat ataccatgcg ccagactgct ggcattagat ttgaggcaga aaaatgaaaa
    13681 ccaaactacc gactgaatgg caagaactga gtgaccaact cggtttccaa gaattcaccc
    13741 ccattcaaac tcaactattt gagccccttc ttgctggaga aaacctccta ggagtgagcc
    13801 aaaccggaac tggtaagacc ctagcgtatc tcctaccaag tcttctcaga ctacaaaaga
    13861 aaaaagccca acaactcttg attctagcac caaatacgga acttgctgga cagatttttg
    13921 atgtatgtaa aacgtgggca gaagctatcg gattgactgc tcaactcttc ctttcaggtt
    13981 caagtcagaa acgacaaatt gaacgtctta aaaaggggcc agaaattctg attggaactc
    14041 ctggccgtat ctttgaactc attaaactta aaaaaatcaa gatgatgaat gtggaaacca
    14101 tcatcctgga tgaatttgac caattactag atgattctca gattcacttt gtagaaaaaa
    14161 tcactcacta cgcacctcgt gaccaccaac tggtctacat aagtgccacg accaagtttg
    14221 accaagaaaa gattgtgccg aatacacgca ctattgatct ctctgatcaa aaattggaca
    14281 atatccagca tttctacatg caggtagacc aacgtcatcg agtggatatg ctacgaaaac
    14341 tggctcatgt agaggatttc cgtggtctag tcttcttcaa tagcctgtca gaccttggga
    14401 atgccgagga aaaactacag tatcgtgata tattggctgt ttccctcgct agtgatatta
    14461 atgttaaatt tagaaaagtc atcttagaaa agtttaaaga taaccaacta accctgcttc
    14521 ttgcaactga ccttttggct cgtggaattg atatcgatag cctagaatgt gtcgtaaact
    14581 ttgatattcc tagagatagc gaaacctaca cacaccgtgc tggccgtact ggtcgtatgg
    14641 gcaaggaagg ttatgttatc actctcgtca ctcatccaga agaaatcaaa aaacttaaaa
    14701 agtttgcaag tatccgagaa attgtcctaa aaaaccaaga actctatatc aaataaagcc
    14761 ccattgctct atacacatcc agtgtatgga gcttttttat aagcaattca attttatact
    14821 catctgcttt caaaaagcat tctagtccat ctccgattaa cgatggactt tatcacatcc
    14881 ttctccagtc cttgtatgac atcttggagt tgattcatga catcttccaa agttcgaaag
    14941 gctttattct taaatccacg tttacgaatc tctttcaaca cttgttcaat gggttcatct
    15001 ctggtgtgta tggaggaata aatgcaaagc caatattagt cggaatcttt aaggtacttg
    15061 atttatgcca tatagcattg tccataacga gtaaaagata atcatctgga taagcttgtg
    15121 aaagctcttc taaaaaggcg ttcatccact cagtattaca tccaccagct attaagaaaa
    15181 atgattcgcc tgtatgggca tcaacagctc cataacaata gcgaaattct cgtatatagt
    15241 gactgtggac atgtgaacct actcctattg gagaccaaca agatcccagt ttactgattc
    15301 taccgaaacc agcatcatct tggtacatca agcgaacctt atgaaaaggt ctactggttt
    15361 taaagcgctt tcttgtcttc ttgaattgag attttatttt tagacgcgac aatggtttga
    15421 gcatctgctt tcctaggatg ttctggacgt ggcgtaatat ttcgccaacc atggcgcttc
    15481 aacagttgat agaaggcatc acgtgtgtag gaacgaccta actccttttt ataagcctga
    15541 aataaggcat caattgtaac aaattctcct gcctctgcag ccttcaaatg acgggcaaga
    15601 aaggctttct cttcctcaac tgtcatatat gcatggttac gaccaccacg tgtttcttga
    15661 aggagagagt cgagtccgaa ctcctcatat ttttttacat tttgctaaat cgttgtttga
    15721 ttacagtcta aaagctctat aatctcttta taagatttgc ccatcagacg aaatagaacg
    15781 atttgaaggc gtttatgata tttagctgta cgagagtctt ttaaaagtgt tttgatggtt
    15841 tggatttctt ctttagttga tttcatatta ctattgtata atgctttttg atttgagtct
    15901 agtattatac tcttcgaaaa tctcttcaaa ccgcgtcagc ttcgccttgt cgtatagatg
    15961 ttactgactt cgtcagttct atctacaacc taaaaacagt gttttgagca gtctgcagct
    16021 aactttctat aacaaaatga aataagaaca agacaaatca atcaagacaa tcaaatcgat
    16081 ttctaagaat gttttagaag tagatgtgta ctattctagt ttcaatatat tatagtttgc
    16141 tctttgattt tcattgagta ttagttcaat atctaaaaaa agaaccttgc caagcaagat
    16201 tcttttagtg tctgacttaa ataattgttc ttctgggaac taaatcgaat taagcttcga
    16261 tttctgtaac catacctgaa ccaacagtac gtccaccctc acggatagag aatgtagtac
    16321 cttgttctac ggcgattggg tgaatcaact caacatcgat tgtcacgtta tcaccaggca
    16381 ttaccatttc agtacctgct ggaagttcga ttgaacctgt aacgtcagta gtacggaagt
    16441 agaattgtgg acggtagttg ttgaagaatg gagtgtgacg tccaccttct tctttagtaa
    16501 ggatgtagac ttcacctttg aatttagtgt gtgggttgat tgaacctggt ttagcaataa
    16561 cttgtccacg ttcgatttca tcacgttgaa caccacgaag aaggacacct acgttatctc
    16621 cagcaagacc ttcgtcaagt tgtttacgga acatttcaac accagtaaca actgcttttt
    16681 gagtttcttc tttgatacca acgatttcga tttcgtcgtt gactttaacg ataccacggt
    16741 cgatacgtcc tgaagcaact gtaccacgtc cagtgattga gaatacgtcc tcgactggaa
    16801 gaagcaatgg tttgtcagtg tcacgttctg gttctgggat atactcatca actgtgttca
    16861 tcaattccat aacgatgtct tcgtatttag agtcaccttc aagagcttta agtgctgaac
    16921 cttggataac tggaagatcg tcacctggga agtcgtattc tgacaatagg tcacggattt
    16981 ccatttcaac caattcaagc aattcttcgt cgtcaaccaa gtcaactttg ttcatgaaga
    17041 cgataaggtg tttaacacca acctgacgtg aaagaaggat gtgctcacga gtttgtggca
    17101 ttggtccgtc agttgaagct actacaagga tagctccgtc catttgagca gcaccagtga
    17161 tcatgttttt aacgtagtcc gcgtgtcctg gagcgtcgat gtgagcgtag tgacgttttt
    17221 cagtttcgta ctcaacgtgc gcagtgttga tagtgatacc gcgttcgcgt tcttctggag
    17281 cagcatcgat agacgcatag tctttaggtt ggttaactga tgaaggcaag cgacgtgcca
    17341 aaacagttgt gatagctgca gttagggtag ttttaccgtg gtcaacgtgt ccgatagtac
    17401 caatgttaac gtgtggttta ctacgatcgt atttttcttt tgccatttga gtaaaagcct
    17461 ccaataaaat atattttata gatagacagt aggcaataca gtctaacttt ccttactatt
    17521 ttatcaaatt tcagctaaat tgcaagtgtt ttacaacgtt tttgtgaatt attcttggta
    17581 aaaatttaac taattaatag aaagtactaa atagacttat ccttcaagga gttttcagca
    17641 ttatccatcc actcacttgc tgaaaatgta aacagtctct ggtttatata gtaaaatgaa
    17701 acaagaatag ggcaaatcgt tcaggacagt caaatcgatt tctaacaatg ttttagaagt
    17761 agatgtgtac tattctagtt tcaatctact atacaacctc aaaactgtgt tttgaacaac
    17821 ctgcggctag cttcttagtt tgccctttga ttttcattga gtataaaatt gcagataaaa
    17881 cgataacaat cataggactc agcagagtca atgtaggtcg aagaatagcc cccctaatcg
    17941 cttattttat agtaaaatga aatagaaact gaacattttg ttgaggaagg taaatcaatt
    18001 cctcacaatg tttgagaaag aagggaggac tattccaact tcaacccact ataaagcaga
    18061 cttacaagat agggaaccca tctccgataa tatatagtag aatgaaaact gcacaatttg
    18121 attggagaat tcaaaccaat ttctcacaat gttttagaaa caagggtcta ttatttcaac
    18181 tgcaacctac tatagtccat tgaagctgga atagcccact gagacttcta aaccactgct
    18241 ggagaggagt ttgtttagag tttctttcat ttccctaaaa aatcaaaaag agagaaccag
    18301 tctgatcctc tcttacttat agatggtgct cactcaaatg ttaaaggagc tatttcttag
    18361 agataaagga atttgaatac agctactgcc gcaattgctg ctgcgatagg tgctactact
    18421 ggtacccaag aataccacca ttttgaatcg cctttatgct caccaagaac tgattttgga
    18481 aggaaagcat gaaggagacg tggtcccaag tcacgggctg ggttcaaggc aggtcctgta
    18541 ggtcctccaa gtgatgttac caaagccata acgaggaatc caagtgccaa gtgagccaca
    18601 gaaagtcctg aagcagtgtg tggagccacc tgtgctttaa tagccaagtc agaaaaatca
    18661 actgtttgtc ctgcttctgt tgccttttgt ttcatgaatt gaagcacttc agcaccaaag
    18721 aagtttttag tcaaaccaag agctgcaaag aacaaaacaa atgaaccaac aaactcatta
    18781 atcaaaccat tgacagttgc tgcatagcga ctttcttttg taccatggtc aatacttgaa
    18841 atagttgaga aagttcccaa gatgttattt gggttttcag ttttcaagta gaatggacgg
    18901 tatgttgcca caactaaggc ttggccaaag atagccccca agacttgcgc gataatgtaa
    18961 ggtaccactt gtgcccaagg gaaaagaccg ctaactgcaa gccctagagt gaaagcaggg
    19021 ttgatgtgat tcccagatac gttaccaaac atcaaggctg ggatcataac ccccatacca
    19081 taaccaacag cgatgacgat ccagccactt tggtgacctt tcgtaccttt aagttcaacg
    19141 ttggcaactg caccattccc aagaatgatc aaaatggcag ttcccaaaaa ttcagtggca
    19201 tacttcagtg cccatgtgaa atccatttgc tagattctcc ttaaaatttt ttagatattc
    19261 cttattttat caatttttac cctatttagc aactgatttc tggaaatatt tttaaaaaaa
    19321 taggattcat agtttcccag ttcaacagac ttgtaagcgt ttttattctt tacgaaagac
    19381 ctcgttctca aaaccaggaa aaaagcccac atctgtgagc ttttcctggt tcctagattc
    19441 taaaatctat tatttttcat cttctttttt cttgaaaaat cctaatccta gaccagctaa
    19501 caaggtcatg ataccagcac tagccaaggt agcattagct tctgtacctg tgtttggcaa
    19561 ttcctctctc ttacctgtct cataagtcgg aacttctggg tctggattca ctggagtttc
    19621 agtttttgga gtacctggtt ctggagttgg tttatctggt gttggagtct cttgatttgg
    19681 tagttctggg tttggtgtcg gaacacttgg atgctctgga tttggttgtg ggattggttt
    19741 ttctggtgtt gataaacggt cataccttac cgttatttct ttatcactag agtctgacgt
    19801 aacttcttgt gattcaactg ttggaatatc tggatctttg tacttgtcaa tcttaccaga
    19861 tataacctcg tcccagtttc ctgttgtcca ttcaccgtag gttacaactc ccgtgacctt
    19921 gttctcagtt tttgtacggc ttaaggttac aggttgaaca acatcttctt ttacattttg
    19981 gttcgtaact ttatcaacgt aatgaatgat acgcgttata gtcttcgtct cagtagaggt
    20041 tgctgttttg ggaaccactg tttcctcaac attctcacgg tagtaatagt caactgttgc
    20101 accgtcttct ggtacgcatt tgcaggagtt gctaccaagg tgtatgttgt tttccttgtg
    20161 ataactcggt cttctttgtc ctcagttgtt gttttccctt caatagtttt tgattctgtg
    20221 gtatactcag aacctatcgc taaatcagct tttataacag actctaccaa cttctcttgc
    20281 ctaccttctt tatagtaatt ggctgttact gtagcagtgg ttggcgcttc gctttctcta
    20341 taaactaagg tcactgttct accttcgctt acaatattcc cagttaaact tgcagaattt
    20401 gtatctgctt ctttaaaagt ataatatttt ccgtcagtag tagtcatgct actgagtttt
    20461 ttatctgtga cattatagct ggtaccaatc agttgttttt tattggtaat gtaggttccg
    20521 tcactttctt tttctccaat tccagtatca tttttcaatg atagcaaacg cccttgttca
    20581 tcaacatagc gaactttcac attttctgag attagttctg ccaattctga ggtttttttc
    20641 tttttcttga tttcttcggt tattttccct ttctcttctt cgggaatatt tagttttgga
    20701 atgatttttt caacaacggt tcgtgatggt tccacagtat cttggatgac tgaaaagtca
    20761 gctagaattg ggagattata ctgaacacgg tgactttgag tgtttactcc tactctttca
    20821 ttattctctg aaaatacttg tacggtataa gaaacaacat cttttcctaa tagaatatcc
    20881 ccagtagaga aatagccgcc ttttcctagt ttgctatctc cagagcccac ttctttccta
    20941 atcttatcag atagtttttt accagtcagt acattcgttc gcacaatccc tttgtctacc
    21001 cctacaaagt gggagaactt tttgaactct tcagaaccag atctagccca accattatta
    21061 agggcatttg cttttgtatt tgtattctct ctcaaaagtt tggcgattag aattatattc
    21121 atcggcactt agagttgctg ctatatctga ctcttgaata ccaacttcct tactaccatt
    21181 tctagcggca gtatatgtgt atttatctgt ttctacttct agctgattat ccttaacatg
    21241 ataggtaatt ttctcctggt ataagagtct tcagtagttt atatactctg tcatcatctt
    21301 tagctttaga agcagctgag tttagccaag ttggggtatt aggagtatct ttatcagcct
    21361 gtttcaagac attattcaag tcatttgcta gcctattggt tatcctcact gtgaaagttt
    21421 tcttccagtc tgaaccactt ttattagact tagatatgct catgaaatcc tggtcaacat
    21481 tcaacacaat atcgccttgt tttttagcat cttccgttgc ttctgcttca aattgatcat
    21541 ggagtttttg ttgctctggt gtatagtttt tttatttaca cgatttaatg tactattttt
    21601 tattttagta ttaagaactc cattaatacg atttttaaac tctgcttcaa aaaatccctt
    21661 aatttgttgg tgcgcaagtt caacattcaa acctttctta tacaagtctt cattctgaac
    21721 gatttcggct acacggtgaa tggtttgatt gtataccgtc ttctcttaac cagcagtatc
    21781 cttagtttta atgactactc gataggttcc tttagaaccg ttatagtcat ctagttttaa
    21841 aaaagcattc caaacattca aaaatagttg gaacttccct taatacatcc gtcactttct
    21901 ttttcaagat agcccaagct tgctcaatag gattcaaatc cggtgaataa ggtggtagag
    21961 gtaagaaaaa gtgtttatct tggatgcaga gttcatccaa aatgttcttg ggatgaaaac
    22021 cagcattgcc catgacaata acatgaggtg tcttcaaagc aggtaggagt tgcgttttga
    22081 accactccac aaagaaatcg cttgtcatgc ttttcttgta aatcatggga gctataaact
    22141 ctccgtctac ttgtcctgca acaattgaag ttcgctcaaa acgacgtccg ctaatctttt
    22201 catagacttt ctcccctcta ggagcccctg cataaggacg atagagatag cggtcgattc
    22261 ctgtttcatc aatataaaca ggtgctaggt gctttaaact attaaaattc ttaagaaata
    22321 aggctacttt tctgggtctt gttccttaaa gctcgtcatc tttttttaaa gtgaccttaa
    22381 tctgctttaa agctgcccat actgaaggaa cagcacaatc aaaatgtgcc gcaatttccc
    22441 gtaaaaaagc atctggatga gcctctacaa aggctttcaa ttcctctaaa ggaatctttc
    22501 ggtttttgac gactcgcttt ttcctctcta tgtgttcttg ttcacgtctt tcttttccca
    22561 cgtgaagaga gttctgacgc caacaccaaa aaacttggct gcctcgacat ggctgtgccc
    22621 ctctttgatg taatctaatg ctcgctgttt aaaatcagta ctatatgcca tagctttatt
    22681 ataatatgct tgtttaaaac taagtaacta tatcaatgtt ttgttatgag aagatttact
    22741 ttttttactg aaattgaatt tttcctagcc tcaacatcat ataaccccaa aattcaatct
    22801 gacctggttt gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat
    22861 ataattaaac tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa
    22921 attaccagaa atgggttgat tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa
    22981 atatggacga aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag
    23041 gtatgcgtgg cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag
    23101 ctactgaagg attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg
    23161 tagcaattgc ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag
    23221 ttcttgctaa acacggcatc aaatcttacg tatttgaaag ccttcgtccg actccagaac
    23281 tatcatttgc agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca
    23341 accctgctcc atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac
    23401 acgatgcgga cgctttgact acttatatcc gtgcaatcga aaacccattt gcagttgaag
    23461 ttgctgatgt ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagctgttg
    23521 acatagaata ccttaaagag gttaaggaca taaacatcaa cccagccttg attgaagaat
    23581 ttggtaaaga catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc
    23641 gtcgtgctct tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg
    23701 ctgacccaga cttttcaact gtaacatctc caaacccaga aagccaagca gcctttgccc
    23761 ttgctgaaga acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg
    23821 ctgaccgtgt tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta
    23881 accaaatcgg tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc
    23941 ttcctgaaaa tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg
    24001 ctgaaagcta cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa
    24061 aaatccaaga attcgaagaa aaacacaacc acacttacat gatgggattt gaagaaagct
    24121 tcggttactt gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtag
    24181 ttgctgaact tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag
    24241 aaatctataa agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg
    24301 tcgatggtgc tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaacag
    24361 aatggaacgc aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg
    24421 ctgacggtac tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg
    24481 ctgacggttc atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca
    24541 ttgcagttgt aggggaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag
    24601 aaatcaatgc atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt
    24661 tttcgtatca aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa
    24721 gcgaggtaat ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt
    24781 tgtgcgtgcg caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa
    24841 aacttgccct tactgccgta aatttgcagg tacattgtca ggtgtcgtag ctgaaaccaa
    24901 agctcacatt tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt
    24961 ccgctcacgc tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat
    25021 caacgtccgt tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta
    25081 aaaaatcagc taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt
    25141 gatattatgc gttttattgt tcctaaaaca gttacatcag tatttcatta cagaacattt
    25201 taattttgga agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca
    25261 tattcaatta tccatattca atcgctatta tcgttttcct agattacaaa aaaaactacg
    25321 ttttgctaat caaaacgcag tttcagccac tattttatct tactgtcctt cttttacttc
    25381 tttggttgct acatcttctc caaaccattt ttggctgatt tcttggaact tgccgtcctt
    25441 gtaaagacta gaaaaagctt catttatctt cttaaccaag tttgtatctt ccttacgggc
    25501 tccaaccgca aaagcttctg tttctagtcc aactgtaaag acattataat cgtttaaaac
    25561 accttctgct tctaaataat agtttgcata gacacggtca atcaatagac catcaattcg
    25621 atcgtttttc aaatcaatca aggcttcatt aaaggtttgg tattgattcg cttccttatt
    25681 agcgacaata ttcttcaaaa tttctggatt tgcttcaaag tccgcataac cagatgaacc
    25741 agcttgagct cctaatgtct ttccagtcat atcctttgca gtcgtgatac cagatgattt
    25801 cttcgtaacc aatacctgct cattcttcat atatgagtta ctgaaagcca ccttttcacg
    25861 gcgttcgtct gtagcggaat agccattcca aatcagatca atcgttcctt ttgtcaattc
    25921 agcttctttc aaatcccaat caatcggttg ccaatttacc gtgattccgt atttttcaaa
    25981 aacagctgta gctaaatcaa tatcaaatcc tgcataagaa ccatctttct gagcaaatcc
    26041 cattggaaca aaagtactat caaatccaat agtaatagac ttgttagact ggtactttga
    26101 ccaattatct ccactagttt cgctagaatt tttcccacaa gctactaaga acaaagcagt
    26161 catcagactg actaatacaa gcatccattt tttcatccat ttttcctcct atttaggttc
    26221 tactttcaat aatacatctg cgatattttc agcaaactgc aaatcatggg taaccacaat
    26281 ctgggtcatc ccaagttccc tattttgcaa gattagcttc tccacttcca aacgtaattc
    26341 tggatccagg gcagaagttg gttcatcgta gccaatgatt tctgggtcaa tcatcatagc
    26401 acgcgccaaa gccacccgct gcttttgccc accagatagt gagaaaggat aggcctctgc
    26461 gtgtcctcct agtcctaact gttccaagag cccactcgcc ttcttctcag cctcttcctg
    26521 cttcattccc atggtcttca caggcgataa agtcaaattt tccagaactg atagatgagg
    26581 aaatagttga aaatcttgga agacaaatcc cagtaggttg cgcttctgca attcatccag
    26641 ctctaaaggt tgtccattat aaaagatttg ccctgaatca atggtttcaa gacctgcaag
    26701 catacgtaaa agagttgtct tacctccacc agaaggtcca acgatagcca ggatttgctt
    26761 ttcaggaata cttagactga aatcagacag gatttgtttg tctccaaaga ctttattgat
    26821 atttcgtaat tctaacatag ctgcccccta tctataataa ctatacttct tctcaacttt
    26881 tttggaaata attgtcacaa tcccaattaa aatcaagtaa atggctcctg ccaagaacat
    26941 aggaaccaga ctagcatcgc ggttagcagc tgttcgacta gccaagataa ggtctgaaat
    27001 tccgagagca tagaccaaag aagtatcctt gaccaaactc ataacttcat taaagacact
    27061 aggaagaacg atcttggtca cttggggcaa gataatatag cgcactctgt caaaagggct
    27121 aaacttcaag accttggcag cctcatactg tcctcttgga atagtgtcaa ttcccccacg
    27181 gaaaatttct gcaaagtaag ctgcatagtt gagaacaaag gcaataatag ctgcaggaag
    27241 gcggtctaaa cgaatcccaa tacttgggag cacataatag ataaaaatca gttgcaagag
    27301 taagggggtt cctcgcataa cccagatgta aatgttaatc agataatgga ggggcttcca
    27361 atggacttgc aaggcaaagg caatcaaaac gcccaaggga atcgaaaata gcaagaccag
    27421 tgcaaagacc tgtacagtcg tgctcgcacc attcagtaaa ctcggtaata tctcaaataa
    27481 ataagacata ctgcacctcc taaaagtaat tgttcctatt atagcatgaa taaacaagat
    27541 taccaagtat ttttgtaaaa agattctacc atatacaaat aaaaaccgta gctatcaaaa
    27601 gagataaact acagttctat atgtttaaac attcttacaa tctctcaaac agttcttgca
    27661 tttgcacatc atctggaacc agttttaagt aagtgtgagc atggactttt gcttcttcaa
    27721 aatgtcccaa ttcacgcaag agatagatat agtgttccag aaattctgga ttgtccttca
    27781 aatctcctgt caactcttga taatgctcat aagcagtatc caaatcgtcc atttcttgat
    27841 aagaacgagc aatcatccac ttggtcaaaa gattttctgg ctcctcactc tgcaagtcta
    27901 gaatatcctc ataacgctcc tgctccagat aaatagtggc taaacgaagc aagatttctt
    27961 ctgtatcctc agcgtcttct tttgcagtaa ggagataatt ttctgcacca ctagcatcat
    28021 gcaattcata agaaaattgt gaagcagcta gcaagaggcg agtttcaaag ggatttttct
    28081 ctaatccttg cttagcgata cgcagggctt cttgaacttg atgttcctta tgtaaagcct
    28141 gactgtaccc atactcatag ccttcaaagt caggagaaat ggtatcaagc tgcttaaagt
    28201 agagggtggc tttttgatat tcttcttgat caaaataaag actggccaac tcaaaagctg
    28261 ttaagtcatc gtattctaac tccagggctt tttctaaaaa ctcagtagcc gtttcaaatt
    28321 tccctaactg agcataggca aagccaattc gttgataggt ggaaatgccc gtttgctcat
    28381 aaatcgagcg attatctaac tgggcatagg cttgaatagc cgcttggtaa ttttccaact
    28441 cactatccaa ctctgccaaa cccaatatca agagagaatc ctctgagtag gtcaaggcct
    28501 ccaataattt ctcacgtgcc acatctgtca aaccttccag ctggtaaagg tctgccttca
    28561 aaaccaaaga cgagacatac cagtcactgt cagcttggat ttcctcaaga taggtaaagg
    28621 cttcttctat ttgaccatcc tcgctagcaa ttgcagctag attaagatga acctctggaa
    28681 aatcctctac aattttcagg taaatttcct tggcctgagg atagaaacca atcccttcaa
    28741 gataagttgc caactcatac agaagatcac ttgaatcatt ttctaaagct ttggcgaaat
    28801 aatgctcagc cttagttaaa tcttgctcct ccaaagcctg taacatctgt tgactattgt
    28861 tcactcttga cttcctcacc ctctaattca tatagaccac tgactacctt ataccattcg
    28921 aaaatggctg aaatgacaac cttagcagag gcataaaccg gaataccaag taaaactccc
    28981 cagataccaa acatagatcc tgaagttaac aaaacaaaga gaacattaat agggtggatg
    29041 tttaattgac ttcccaaaat caatggagag acaaaacggc cttcaatagt ttgttctacg
    29101 ataaagacaa tcactacttt caaaagcatg actggaccag caatcaaacc caataccagg
    29161 gcaggaagca tggctagaaa gctaccaaga taagggacca gatttaaaat accagcagta
    29221 acccccagcg taaccgcata gcgtagacca ataatcttga agaagatgat aaacattact
    29281 gctacaataa tagccactgt cacttgccct cgaacatagt tggacaactg ttgattcaca
    29341 tctgatagaa cttgtccaac aggttccttc aattttcttg gaatgaattg ggtcaaataa
    29401 ttacgcaagc ctttcccatc acgcaagaga taaaagagca tgaaaggaac gataatcaag
    29461 gcaacaatca cttgagaagc cccgctaata aaggcactca cccagttgac tgcctgagat
    29521 gaaaccttac ttgccaaaac tgtagcctgg ctagaaaaat tggtcaaaac ttgctctaat
    29581 tgaggtctga aatcatctgg caggtgctgg gctaccaatc cattaacaat cctatctata
    29641 tcttctaagt aaacaggaac gtttcttgca aaggtcaaaa cctgacgttg cagatttgga
    29701 atggcgactg ccaagcccca aatgataaag agagcgataa taacaaagac aatagtgata
    29761 gctataacac gattaacctt atgcttctcc atccaatcaa caataggatt caacaaataa
    29821 tataacaaac cagacaaaat gactggcaac atcacaactg ctaaaaagtc taaaacaggt
    29881 gaaaatagaa aactaatctt acttaaaata aaaagattca atcccaataa taaggttact
    29941 aaaaataccg taattgcctt gttatctaaa aaccacttga aaaaccaaga taggctaaaa
    30001 tgtttctctt tttgctccat aaatacttcc tttctattgt tctcccatta taccattttt
    30061 gaaacaaaat aactcttttt taaagtgctt acatctaatt ggatgtcttt aatttgcttg
    30121 tttttgtgat ataatagtct tatctttaca tagaggtata gtaatgaaag aaactgttta
    30181 ttttggaact tatacacgtc gtacttctca agggatttac aaggcagact ttgatacaga
    30241 aactggtcag ctttcaaatc tagaactttt tgcagctgag ccaagtccaa cctaccttgc
    30301 ctttgaccag caccaacatt tatacactgt tggtagccaa gacgataagg ggggaattgc
    30361 agcctatcaa actgacggga ctgtgttaaa tcatgttgtt gaagaaggag ctccccactg
    30421 ttatgttgct gtcgatgaaa agcgtgattt ggtttacgca gccaactatc acaagggaca
    30481 agtccttgtt tataaacgcc aggaagatgg tagtcttcta cttagtgata tggatcaaca
    30541 cagtggccaa ggtccacatg aaaatcaagc ttccccccat gttcactata cagatttaac
    30601 acctgaccac tatctagtga cctgcgactt gggaactgac caagtcatca cctatgacct
    30661 cgatcaagaa ggaaaattat ctaagctcta tacctatcac agcaagccag gagcaggctc
    30721 acgccatatc attttccata accactataa aatcgcttat ctcatttgtg aactcaatag
    30781 tactatcgaa gttttaatct acgatggcgt tggcgaattt gaacgtatgc aggtcatttc
    30841 aactttaccg gaagcttacg aaggctttaa tggaaccgct gctattcatc tctctaaaga
    30901 cggtaaatac ctctacgctt ctaaccgtgg ccatgattct atcgcagtat ataccatcct
    30961 tgcggacggt agcttagagt tattagaaat cgttccaacg catggtcaga ctccacgtga
    31021 ttttgatttg acacccgacc aaaaatttct cattgttgtc catcaagact ctgacaatgc
    31081 aactgtcttt aaacgtaatt gtgacaatgg tcgtctagca gaactctcca acgacttcca
    31141 tgttcccgaa gcagtctgca tccgttttgc tccttaaaac accataaaaa atgaacttgg
    31201 tattttcaag ttcatttttt cttatagtct atttccgaca ttaatacggt taatggcacg
    31261 ttgcaaagca atcttagcac gacgttcttg gtcaatcaaa tgtttgtctt gtgcttcttc
    31321 aattgcacgt tctgcacgaa gtttggcacg ttctgcacga ctgatatcga tatcacgagc
    31381 acgttctgca gagtcagcga cgattgtaat catatcattg gcaatttcaa taacgccacc
    31441 gtttactgca atccagttca cgtgatcttt atcatcgata cgttttacct ttacttcatc
    31501 aactgctaaa accgcaatca tattttcatg tcgtggcaag atccccatct caccatccag
    31561 agttcgaacc gatacatagc tggcatggtg atcatagacg agaccatctg gtgtcacgat
    31621 ctggacagtt aactgagcca taggtcacct cttaaaatcc cattttttca gcttttgcaa
    31681 tcacatcttc gatagaacct acaccacgga aggcatcttc tggcaagtgg tcgtatttac
    31741 catcaaggat ttccttaaag ccacgtacag tttcagcaac tggaacataa gaacctggct
    31801 gaccagtaaa ttgttccgca acattgaagt tttgtgacaa gaagaactgg atacgacggg
    31861 cgcgagcaac caaggtcttt tcttcatcag aaagctcatc cataccaagg atagcaatga
    31921 tatcttgcaa ttcatggtaa cgttgaagga cacgttttac ttcagcagca actgcatagt
    31981 gctcttctcc aacgatttca ggtgccaagg cacgtgagct tgaagcaagt gggtcaacgg
    32041 ctgggtagat acccaattgt accaacttac gttccaagtt tgttgttgaa tccaagtgag
    32101 cgaaggctgt tgctggcgct gggtcagtat agtcatccgc tggcacatag atagcctgga
    32161 tagaggttac agaacccttc ttggttgatg tgatacgttc ttgcaattga cccatttccg
    32221 tagcaagtgt tggttggtaa ccaacggctg atggcatacg acccaaaagg gcagatactt
    32281 ctgaaccagc ctgagtgaaa cggaagatat tatcgataaa gagaagcacg tcttggcctt
    32341 ccacatcacg gaagtattca gcgattgtca aaccagtaag ggcaacacgc atacgtgctc
    32401 ctggtggctc attcatctga ccaaagacca tggctgtttt ctcgataacg cctgattctt
    32461 tcatttccca gtaaaggtca ttcccctcac gagtacgttc cccaacacca gtaaatactg
    32521 aaataccacc gtgctcttgg gcaatgttgt gaatcaattc ttggattaag acggttttac
    32581 caactccggc accaccgaaa agtccaactt taccaccttt aaggtaaggg gcaagaaggt
    32641 caataacctt gatccctgtt tcaaggattt cagaagaggt agacaactca tcaaaagttg
    32701 gagctttttt atgaattggc tgacgctctg cgtcttctgt aaaaggagct tccaaatcaa
    32761 tggtatctcc caaaacgttg aagacacgtc ccaaagtttc tttacctact ggtacagaga
    32821 ttggacgacc tgtgtccaat acttccattc cacgagtcaa cccatctgtt gattccatgg
    32881 cgatagtacg aaccatacca tctcctaact ccaaggctac ttcaaggacg atttttgttt
    32941 ttctttcgtc atttttgtag acgacaagtg cattgttaat ctcaggaagt ttttcccctg
    33001 ctgcaaacaa aacgtctaca acgggaccga taacctgagc aattttacct gaactcatct
    33061 ccttctccta ttctatataa gatactgtcg gttcctagct caactaggtc ctaagttcat
    33121 tttcatacga gctggactag agcctattct aaggcactag cacctgctac gatttctgta
    33181 atttcttgtg taatcgccgc ctgtctggca cggttatact gaattgtcaa atcattgatg
    33241 actttcttag cattatctgt cgctgtttgc atggctgtca tacccgcagc attctcagct
    33301 gtcttggcat cgataatggc accgtaaatc atactttctg caaactgagg caacaactgc
    33361 tccagaattt cttctcggct ggtttccaat tcaaaagtca agctgtactc ttcatccgct
    33421 tcatttggat ccaagtcaac aatcggaagc atttgttcca cacgcatttg actggttagc
    33481 gtattgacat ggtggttgta gcaaacataa agctcatcaa agagttcatt ttggtacatt
    33541 tcaacagttt ttgaaataat cttacgaact tgatcaaagc taggttggtc tgccaagcca
    33601 cgtaattcat aaagtggttg aataccgcga gccttaaaga aatcagctcc catcccaccg
    33661 atacagatca tttcaaaacc tttaccgtct gggtggtatt cttctttcaa ctccataaca
    33721 gctttcaaaa tagaggaatt ataacctcca accaaaccgc ggtctgaagt gataacgata
    33781 tagcctgtct tcttcacaga acggctaatc aacatcggat tagttgaagc accagctcca
    33841 ttaccatgaa ggatatctgt caaaagttta cgcactttct gagcgtaaac ttggaagttg
    33901 cgagcagctt cttcagagcg acctaactta gcagccgata ccatttgcat ggcattagtg
    33961 atttgactcg tattttttgt tgaggcgatt tttgttttaa tatcatttag agacactgcc
    34021 atctgacacc tctattctta ttggaagcta gattgattga gaaactctgt aatcgcagca
    34081 tccaagactg cttcttctgg caagtctttt gtatcacgaa tggtttccaa aatctctgga
    34141 tgttgagcat caaagaaggc atggaactct tcctcgaaac gaacaatatc atctactgga
    34201 acagtatcca agaaaccatg tgtcaaagca taaagaatgg ttacttgttt ctcaacaggt
    34261 aatggtttgt gaacaggttg tttcaagacc tcaacggtac gacgtccacg gttcaactta
    34321 gcctgtgttg ctgcgtccaa gtcagaacca aacttagtaa aggcttccaa ctcacggtat
    34381 gaagcaaggt cgatacgaag tgtaccagca accttcttca tggctttgat ttgtgcagaa
    34441 ccacctacac gagatacaga tgaacccgca tcgatggctg gacgaatacc tgcattgaag
    34501 aggccatcgc caaggaagat ttgtccatca gtgatagaaa tcacgttggt tgcgatatag
    34561 gctgagatat ctcctgcttg tgtctcgata aatggtaggg ctgtaattga tccaccacca
    34621 agttcatcag aaactttagc tgagcgctca agcaaacggc tgtggagata gaaaacatcc
    34681 cctgggaagg cttcacgacc tggaggacga cgaagcaaga gcgacagttc acgataagct
    34741 accgcttgtt ttgatagatc atcgtataca atcaaaacat gcttaccttg atacataaat
    34801 tcttccgcca tagcgacccc agtataagga gctaggaaga gcaatggaga tggttgtgaa
    34861 gcagaggctg tcacaacgat tgtgtagtcc aaggcaccgt actgacgaag tgtttctact
    34921 tgcgtacgaa ctgttgattc tttttgtcca atcgcgacgt agatacagat catatcttga
    34981 tctttttggt tcaagattgt atcaatcgca atggttgttt tccctgtctg acggtcaccg
    35041 ataatcaact cacgttgacc acgaccaatc ggtacaaggg cgtcaatagc tttcaaacca
    35101 gtttgcaatg gttctgaaac agacttacgt tgcataacac caggagctgg tgcttctact
    35161 ggacgagttt tatcagtgtg gatttctcca agaccgtcaa ctggacgacc aagcggatcc
    35221 acaacacgac caatcagact ttcacctaca gggacttcca tgattttccc tgtacggcgg
    35281 attgtatcgc cttcacggat atctgtaaag tcacctagga tgataatacc aacgtctgtt
    35341 gactccaagt tttgagccat accataagag ccgttttcaa aattcaacaa ctctccactc
    35401 atgacatttt caaggccgtg agcacgcgca ataccgtccc cgatataggt tacaacacct
    35461 gtttcagtca catcaaaatt gggtttgaaa ttttcaattt gttgcttaat taaagcgctg
    35521 atttcttgtg cgttaattgc caaaagaaca ccactttcta tttcaaattt tctttaacaa
    35581 ctttaagttg ttgtttaata ctcacatcaa ttgtcttgtg attggcaaaa atgacaaaac
    35641 caccaatgag actttcatcg atttgttctt ttacactcct tactttcaga gacatttttt
    35701 tctcaatcaa agggagcaaa cgagtcttct gttcatcagt tagaggatga gcagacgtaa
    35761 tcgtcacttc aaatcgattt gtttcttttt caagtcggtt caagcaatct acaagcacat
    35821 cataaaaaag atttgctctg tgattgtagg ccagaacctg gataaagttt tgtaataaag
    35881 gcgacacaga atcttggaaa aaagcaattg ttttttcctt atccgactcg tctactgcca
    35941 cttgttttaa aaaagaaggc agacctgttt tttcaacaac ttgcttgatt tgagtcaagt
    36001 ctgaaaagat acggtcttct tctccttttt caagtaccaa ttggacaaaa ggcatgctgt
    36061 atttttcaat tacctttact gttttcttgt ccattaagct tctcctagct gatcgatata
    36121 ctgatcaatg agtgctttat gggcatgact gtcaaggttt tgtgagatga ttttaccagc
    36181 taagctgatg gtcaaatctg cgacctcacc cttaacactc tgtaaagctt ctactttatt
    36241 ttgagcaatt tcttgattgg ctttttcttt taagtgtcct gcttctagtt tagcatctgc
    36301 taagatatta gccttacttt gctcagctgt ttcctttgca ttttcaatga ttgtcttagc
    36361 ttctttacgg ctaccagcca attcatcttc gcgtttttga gccaatactt ctgctttttg
    36421 acgggcttct tcagctctgt caatatctga agcaattttt tcagctcttt cttcgaaaat
    36481 gcctgtaata ttagaccatg caaatttttt aatcaagact agcaaaagaa taaaagagcc
    36541 agtgattaaa ataaaattac caattaattc acctactgtt acgtgcatca gttactcctt
    36601 tctattcctc ttcaatatta atcttattcc ctaaatacac agatgtcaaa agagtaaaaa
    36661 cataagcttg gatgcaggaa ataaagacag aaaatgcagt ccaagccaaa ttagctccaa
    36721 aggctactgg ataccaataa atagcttggt gggaaagaag aagtaacaaa ctcgtcatga
    36781 cctctcctgc aaagatattc ccaaaaatcc gcaaagccaa agataagaag tttgtaaatt
    36841 cttccaagat attcatcggt atgacaaaaa caggactcat aaaagatttt atactttttt
    36901 taaatccacg acgacgaacg ctttctatat gtgtcaacaa aatgacaaga aaagataagg
    36961 ttaagtcata ctgtaaatta gcggttggcg aactccacca gttagtccca tcgatcgttt
    37021 gaatctttgt cattaagcca aggttattgg caatcaccat gaaaaggaat aaacaaagga
    37081 aaaagagtga gtaatctttc atgtagcgcg aaccaatgtt aggttctgta aatccaataa
    37141 caaagtcata gacatactca agtacatttt gctttccttt gggtttcaag gtcatattgc
    37201 ggcttgccca ataaataaag acaaaaataa ctcccacaat caacaaagtc atggctaaca
    37261 tagtcagatt gaagataaca ggaccaatag agatgattgg attaatactt tcttccatct
    37321 aaaatcctcc cttttcttct cgttccatgt atttatttga taataaatga gaagacaaga
    37381 gttacaaaga aagttccttc aataaaggca acacctaaaa acatcaaact acgaaactca
    37441 gaaagcatat ctggttggcg tgctactgat ttaaacagtc cattcatcaa taaaccttca
    37501 ccgacagata cgcccataca ggcaatacat aagcctaaaa atgttaaatt cataacaaat
    37561 tctcctttaa aataaaattt acttacttag tgtagtccta aaatttaaat ttgtcaactt
    37621 ttaaccgcta ttggaagcgt ttaataaaaa ttatttccat tttgctaaat ttcaagttca
    37681 agttagccat ccagaagtct tctctgggtg acttgtagtc caagcatttt ttaggatagt
    37741 tgttaatcca cttttcgatg aatgcgactt ctttgggagt cattttcttg gttcccttag
    37801 gtaaccatct acgaatgagc ctgttgtgat tctcattagt tcccctttcc caagaggcat
    37861 agggatgtgc ataataaatg tgctcctcag aaaatacatt agacaagcga ttgaattccg
    37921 ttccattatc tgccgtgatg gaaagaatct tgtgttgttt taagatgagt tttagagcct
    37981 gattgaccac ctcagcactt ttatttggaa tcaatcggat gatctgatgt ctactctttc
    38041 gatccgtcaa gacaagcaag cagtagtttt tcgatctcgt aagtagaacc gtatcaatct
    38101 cataatgccc attctccaag cgaagattga tagcttcagg ccgctgtgcg atggattgac
    38161 cagcaggttt aaagttggtg ctagcctgtt tcttaagcac ttttcctttt ctagggtaaa
    38221 gcagatcctg cttgcttaac cccaattttc catgatgaat ccaatagtaa atggttgaaa
    38281 ttcccacgtt aaccccttta gccatcacca tcatttcagg cgaaaatttt tggttatgat
    38341 agtggagaat cttttccttt agttccttgg tcaagcttga tttcttgacc gagcgcttgc
    38401 gattgttttc ataagactgt tgagcatagt cggcagaata aacctctttg aagcgccctt
    38461 ttccaagaca ttttcggact gtcctacgct tgattttagt gtggatagtt tgaggagctt
    38521 ttccaagcag agaggcaatt tctctatttg atttcccttt gttcgccttt tgtagtataa
    38581 tggttttgca tctctgtgcc tttcttgtgt ttgtggttga acaacaagta taacacagag
    38641 gtgttttctt atgcctacaa gagctttcat tatttccatt ttctttcgga tttcactcta
    38701 ttctgaaaaa cttgtgtata tttactgaag ctagcaagtc ttacctgtaa atttaatgaa
    38761 agcaacacaa aatccgagag gggaatctcg gattaatgtc aatttaaaaa gatagagagt
    38821 ttttagttta aataaattgt tttaaaatat caacaacatc acttcttttc ttaacctgat
    38881 aagccttgat tcctaatttt ggagctacga ttatattgtc ctcaatatcg tctagaaaga
    38941 cacaatttct aggttataac tggtatttat cgatagttac tcatatatat cagtccacct
    39001 ccatactcac cttacagatt cttttgataa taatatcttt gcctaatgta gagatagtct
    39061 tgcaaagaaa aaacttcctt gtagccatgt ttctgataaa agtccggtgc ctggaactgg
    39121 taagtattga caaaggcaaa acaacaattt cgattcttag cttcactttc tgcctgttgc
    39181 aatagttttg aaccgattcc ttgccctcgc agttcctctt ttacaaacaa atactcgatt
    39241 tctagccaat ttccaaaagt ctctgctatc aaacctgcca ggagattgcc cttttcatct
    39301 tcgacataaa gattaagtgg ctcactttca gcctcttctc tttttgaacg gttataaaca
    39361 cgaatcagat tccctatttc ttgcgattta tgtgattcct tattttccaa tctaaagtat
    39421 aatgaaatga aataaaacat gcgcaaatcg attaaggaat ttaatctaat ttctaataat
    39481 gtcttagaaa tcaaagttta ctattttaac ttcaatgcac tatacatcta atactcaata
    39541 aaaatcaaag agcaaactag gaaactagcc gcaggttgct caaaacactg ttttgaggtt
    39601 gtagatgaaa ctgacgaagt cagtaaccat acatacggca aggcgacgct gacgtggttt
    39661 gaagagattt tcgaagagta gcaaaatgga aaaaggagtg agtgaagcac atcgcctccc
    39721 cactcctttt tctgttttta ggctgttttt tcaaccttca agatttttac atcatagcta
    39781 ccaacaggcg tttcaatggt tgctgtatca cctgttttct tgccaatcaa ggcctgccca
    39841 attgggcttt catttgaaac cttacctgca aaggcatccg caccagctga acctacgata
    39901 atataaactt cttcttcgtc ctcaccaatt tcttggatgg tgactgtttt accaatcgct
    39961 acttcgtcct gggcaactgc gtcgctattg acgatttcag catagcggat ttttgtttct
    40021 aagctagaga tttgtccttc gacaaaggct tgttcatcct tagctgcttc gtactcactg
    40081 ttttctgaaa gatcaccgta tgaacgggca atcttaatgc gttctaccac ttctggtcga
    40141 cgaaccaatt tcaattcttc taattctttt tcaagtttct ccttttcctc aagggtcata
    40201 ggatatgttt tttctgccat ttttctcaac tttcttctga taatattttc taaagaaaat
    40261 tatgtgaagt atcacataat tttagtttgt ttagtttaat ttgctgttga catgttcagc
    40321 gacattgcgg tcgtggtctt cttgattgtt agcatagtag accttgcctt ctgtgacatc
    40381 tgctacaaag tagaggttat cgctcttagt ttgattgatg cttgactcaa tcgcatccag
    40441 acttggacta tcgactggac caggcatgag acctacattt ttataaacat tataaggtga
    40501 atcaatgttg gtatcaatcg caacatcctc agctagactg atattttgcc ccagttttcc
    40561 ttgggcatac aagattgcaa tattactttg aagtggcata tcacgattca aacgattgta
    40621 aaatacacct gcaatgagct tacgatcttc tgtcttggca ccttcttttt cgaccaagga
    40681 agcaatggtc aacaactcat tgacagtcaa gtttttagat ttgatagtac tatagtaagg
    40741 agataggttc ttatccatag cagctaacat ctcatcaatc aagctctcaa tagttgtgct
    40801 ttccttgata gagtatgtag ctgggaaaag gtatccttcc aaacgataac gcgcaccgct
    40861 gtcttttaca ggcaaacttt ccagtaaagt aggatatttc gctactgctt gactgataaa
    40921 cgtctcatct tgaactttag ccaagaaagc ctccgctgtc aaagactctt tgaagtcacc
    40981 ttgcaattga cccacagttt gagcaatctg atccaaggta taaccttctg gaattgtcaa
    41041 agtcgcaagt acaggttctt gcggttcatc tgttccacct ttttgcaact ctttgagtaa
    41101 gtcttctgta ctcatactct tttgcaaatt gtagtaacct gctttcaagt cggtataatt
    41161 tttatacttg gcataaaaac taaaaatcag accatgcttt accaaaccag ctttttcaag
    41221 cgtcgtaccg atttcttgaa cgtttgaacc ttctggaatt ccaaccgtca catatttctt
    41281 agaattagca tcgataggta ataaggaatc tagcacgtac tggtaaccaa agtaaccacc
    41341 tgctgagagc aaggcaagga atacaaggaa tgaaatcaca aaagctttca catgtgactt
    41401 cttctctttc ttaggcttaa cgggttttgc tccttctcta cggctacgac gtgatgtatc
    41461 tctgatgata tccactgttt ctgtagcagg cgtaggtgtt tctggacctg cttgttctgc
    41521 ttttttctct gccgtcgtat aggaaacagc tacccttgtt ggggtttcat tgtattctct
    41581 ttcaagtttc ttaggtctaa caggacctgg acctggtctt gatccacttt cttccgctgg
    41641 agaagaaggt acatcttgac ttggatgact tggaacacca ggagtttctc tttgaatctc
    41701 atctgctgga gaagctggta caccttgact tgggtgagta ggcacggtag gagcttttct
    41761 cataatctcc tctaccgttg acaaggaatc agccatgagt tcttcagctg aaggttcatt
    41821 tgcaggagtg cgaactactg cctcatcttc tttcagaact tcatcatagc cttttacttt
    41881 ttctaaatct ctcagaatct gctctttaaa gcttaatttc tcttcttctc ttgacttttc
    41941 actcaaaagt ttttcctcct tgttgataat ccataatatt atatcttaaa agtccaaaaa
    42001 aagcaatcta tgatactttt cctaacttat tttttcattt cccagaccat atcataccat
    42061 gtttcccctg caaaggttga ctgggactgg ccttcgttga caaatccatg tttttcataa
    42121 taggcgatga gatagtcatg acaggttaga ttaatgccat ctctctcatc ttcaagagca
    42181 acttctttca aggctgtcag caatttctga cccagtccga gtccctgtgc ctccttggca
    42241 atagacagac aggtcacaga gatataacca ccaggctcat gactatagtc ttttatttct
    42301 tctgtaaaag actggtcttg cagatggcgg tgcaggccaa ctggtccttc gatataaccc
    42361 atgattcttc cttctttttc agcaaccaga aaagaggtct gaatttctct caaatgtgct
    42421 tcaaagacag aaggaggaat ggcttcttcg accgaaaaat tttcaaattc aagttcaaca
    42481 atccgatcca aatcttctaa tcttgcttgt ctgattttca ttgttcctcc agataaaagg
    42541 gattaaacca aatcatacta tagccctggc tagttgcata gagcaaagtt gcttcttcat
    42601 caacaaaacc gttcatttca aaataggaaa gcagctcatc aggactctcc aaacgaatcc
    42661 ctttgtaatc cagctcaact gccacctctt tcaaggctgc aagaagaagt gttcccaagc
    42721 cctgtctctg atggtcagac tcgatgacta aagaatgtac ttttagatat tgcggattgt
    42781 ctgactgggg acttgataaa atatagccta aaagttgatt ttcatcccta gctagaagaa
    42841 aggtatccgc acacttacgg atactttctt ctaaaatatg ggaaagttgc tgcttttcag
    42901 ctggaaaaga cgaggtctga agtgccccta tctcaggcaa atcagacttg cttgcctgaa
    42961 tgatcttaat tggaatttcc atgggaacat cctattgaac attgcttgtc aagttagaca
    43021 agagacgctc aaatgagtat tcataggttt ggatgtctcc tgctcccata aagacgtaaa
    43081 cagcattgtc atggtctagg agtggagaaa cattttcaac agtaatcact tggtgttttt
    43141 tgttgatttt gttggctagg tcttctacct taacgtcacc atgatctact tcacgagccg
    43201 agccataaat ttgcgctaga taaacagcat ctgcttggtt taaagcatgg gcaaagtcgt
    43261 ccaacaaggc aatggttctt gtaaaggtat gcggttgaaa gactgctaca atttccttgc
    43321 ttgggtattt ctgacgagcc gcatccaagg tcgcaataat ttctgttgga tgatgggcaa
    43381 agtcatcgat aatcactgta tcattgacaa ttttctcagt gaaacgacgt ttaacaccgg
    43441 aaaatgtttt caagtgctca cgcaccaagt tcaaatcaaa tcctgctgtg taaagaagac
    43501 caataacggc tgtcgcattc atgatattgt gacgaccaaa ggttggaatg tggaattgcc
    43561 ccaagttttg tccacggaaa tgaacggtga aggttgaacc agttgttgaa cgaagaagat
    43621 cactagctac aaagtcattg ccttcagctt caaaaccata ataataaatt ggtgtatcag
    43681 acgtaatctt acgcaattca gcatcttcac catagacaaa aagacccttg gtgatttgtt
    43741 tggcatagtc gttaaaggca ttgaaaacat cctcgagact tgtgaaataa tctggatggt
    43801 caaagtcaat gttggtgata atagagtatt ctgggtggta aggcatgaag tgacgctcat
    43861 attcgtcaga ttcaaagaca aaatatttgg cattggccga accacgacct gtcccatctc
    43921 caatcaagaa gctggtatct gtaatgtgag acaagacatg agacaacata cctgtcgttg
    43981 aagtttttcc atgtgctcct gctactccca tgctaacaaa gtcacgcata aagctaccta
    44041 gaaactcatg gtaacgtttg tagctgatac cattttggtc cgcataggca atttcgacgt
    44101 tgttatctgg acgaaaggca tttccagcga taatttccat atcaccgtct agattctttt
    44161 catcaaaagg aagaatggta attcctgcct gctcaagacc gcgttgggta aagtagtact
    44221 tttcaacatc tgatccctga accttgtgcc ccatctggta caacatcaag gccaaggcac
    44281 tcatccctga tcccttaatt ccgataaaat gatatgtctt tgacatgttt tctcccctat
    44341 tctgtcattc tggtcagatt caactcttgg gcaacccgac gttcttgttc tgtttgttta
    44401 ctttttttat tgtagatttg gctcttcttt agaaaatcat aattgttttt ctttggagca
    44461 ggtgctgaca cttcttcatt cttggtaggg atagaatgaa cttcttccgc caagatataa
    44521 tgagactggg tcaatttttg gctatatttg acaaattcac caggattttc cttttggaaa
    44581 ggagctgtcg gttgattgcc ctgtctaact agactgggct gagaatgacg tctcgcaaga
    44641 ctgaaatcct gagttaggta gttagcagag cgtttctttt tcaagtctgc acgcgcttct
    44701 tcacgcgcca cctccgcata gctctttcct tcttttttaa cccctaaagg agctttttta
    44761 ggtttcccta cttgcttttc aatcggtttt actggttttt cttcagcaat aggagcccat
    44821 tctaaataat ttttatctcg atactcaccc ttgatattac tgatcagatc agactcatca
    44881 tagagattca tgactggcat ttcagtcaac atgacctcgt catctgacac caatggaaat
    44941 cgttcttgtt tcattttcta tttcctttca acacttcatt atagcgtatt gtcttgattt
    45001 ttcaagtgct ggcttcagaa attcccaaaa tttctctaat ttctgctagg gtcagactac
    45061 cacgtgactc tgtgccgtcc aatacttgtg acaccagatg tttcttttgt tcttggagtt
    45121 cctgaatttt ttcttcaatg gttcccttgg tcaccaagcg atagacctca accgtttctt
    45181 cctgacccat ccgatgggca cggccaatgg cttgcgcttc caccgcagga ttccaccaaa
    45241 ggtcaaccaa gatcactgta tctgcacctg tcaggttcag accgacccca ccagccttga
    45301 gggaaatcag aaaggcatct ctttctcctt ggttaaaggc cttggtcatg tcttgtcttt
    45361 ccttggctgg ggttgaaccc gtaattttaa aggaagtcag gcccaagtct ggcagttctt
    45421 gttcaatttt ttccaacatt cccttgaact gagagaaaat caagacacgg tgtccgccgt
    45481 ctgccacctg taccagtagg tctcggagac tatctagttt gccgctggct ccctgataat
    45541 cttccataaa cagggcagga gtgtcacata tttgacgcaa gcgcatcaaa ccagataaaa
    45601 tttccacacg acttcgctga aattcctgtt ctgacacttg agccagatgg tctcgcatct
    45661 gttgtaactg ggcaaggtaa atagcctttt gctggtcttc cagttcattt ttataaacca
    45721 cctcaatcaa gtctggcaat tcagtcagaa cttcttcttt cttgcgtcgc atcacgaaag
    45781 gcttgataaa ctgagccact cgctctgctg gcaatttcat aaattctttc ttgcttggca
    45841 aaagtccggg catgacgatt tggaaaatag accacaactc acccagatgg ttttcaatcg
    45901 gagttcctga caaggcaaag accgacggca ccacaaattg tctcaaggtc tgggcaatct
    45961 tggtctgggc atttttcatg acctgagctt catctaagaa aaggaagtca aaggccatcc
    46021 cctgataaag ctcactgtcc tgacggaagg tggcatagct agtcacatag atttgatggt
    46081 tatcggcaag aatctcctca cgacttgctt tcaaaccatg aacaacagcc acatccaact
    46141 gtggagcaaa tttctgaaac tcatccgccc agttgtaaat caaacccgac ggagcgagaa
    46201 tcaagactcg actttctttt gtcacttgac tagtcaaaaa agcaatggtc tgaagggttt
    46261 tcccaagtcc catatcatca gccaaaatcc caccaaaacc ataatgatgg agcatctgca
    46321 accagccaat tcccttttcc tgataatctc gcaagtcagc cttgacctga gttgcttgca
    46381 aaggaaagtc ctctggatgt gtcaaatcct gggccagatt ctggaattct tgtgaaaaag
    46441 aaacacggtc tcgcccttca aagagatgag ctaaactgta ggctaaggat ttccgagcct
    46501 gcaaggtccc atcttttaat tcaaattgcc ccagttcctg tagattttgg cgaattttct
    46561 tggtttcttc atcgaaaaag taaacttgat tagacgaatc aatataaaaa tcctgattgg
    46621 caaccaaggc ctgtatggct tggtcgattt cctcctggac aatatcttga aaatcaaact
    46681 ggatttccaa gagacctccc ttggaggcaa tctgcacctg aggactcgct aggctataaa
    46741 gctcttctag tttatctgat aggtcaacat gcccgagttt ttcaaagact ggaatgatat
    46801 catgaaaaaa atgatagaca gactccgctt ttaaggcctg acgccaagat tgaaaatcgg
    46861 cttcaaagcc cgcagccaaa cagacttgga aaattctttc ttctaagtct gcgtcacttg
    46921 aaaagggtaa ttcttctagc tcttgtcggc tagatacctg tctatttcca taatcaaact
    46981 gaatttctaa acgaatccga ttatcttctt ccctgtcaaa gtaaaaagag ggcgcaaaag
    47041 ttttgatttg tagacgttct ggagctgaaa cggtgcccat ctggataaaa agagtcagac
    47101 aggaggccaa tttgtctcga tcactgctat caaattgcag gtatttcttt ccttgttgac
    47161 ccacaggtaa cgctttaatt tccttgagaa gacgcatctg ctggtctgtt aaaaaataaa
    47221 cctgaccttt atggaaaagt actgctccct gataaaagac attgacccta ggactctcac
    47281 tgatttccat ttcaaaatag tccgaatatt ctgttactgt aaaggcaaat agattggcat
    47341 cagcatgcat atcctgaaaa agcagggttt ggtagctatc cacttgatgg tcaaattgaa
    47401 aatggggcaa ggccatcagt aaattcacac cctgctcaaa aaaggtcaga gggaaaaaga
    47461 ggtgccgacc ttggttttgg aaaaagaggt ctggaaccag cccttcctcc gttagtccgt
    47521 gcaagaaagt caaaagttct tggctggcat catcaaaggc ttcccaagaa agagactcct
    47581 cataaatctt gccaatcata tacgactttc tctgctcgac aatccttaaa aaaagtggaa
    47641 tatcccgaat gacatagtat ttttggctat tgatttggcc gattctcaga gtccacaaga
    47701 tatgattggt tcctgcttcc acctgaccca cagctgataa ctcataggcg cattctgatt
    47761 ttggagataa aattcgatcc aaaaacttgc cacccaaggt caccttggtt tcaacggcct
    47821 ctttttcttc atgaccttct tccagactcc acaagatttc ctgaccacgc tcatcatttt
    47881 tcagaaaatg ctctagcgct gccaaatgca cacagtagcc cctcttttga aaaaaatcac
    47941 aggcacaaaa aatcaaatca tcctctaaac tatagcgcag ttcttcttct gcaacgcgag
    48001 cgtagagccg attgttcttt tctttgatga tatcaacctt accagtttca taaagggcaa
    48061 caccttcgat acgaattttc cccggaatca atttagccat attttcacct ttaccttatc
    48121 tttttattat accatatttt cgcctatgaa aatagccttc taggaagact tttctcctag
    48181 aaggctggat ttttaacatt tggcaaaagt agccacaatc cgctgacaga cttcttgcaa
    48241 cagagatttg ggcatagcta tattgatgcg ggcatggaga cttccttcct ctccaaaatc
    48301 caaaccacgg ttgaggataa ccttggcttc atttctcaac aactcttgca atgtttcatc
    48361 agtcaggtca taagctgaaa agtcaagcca aatcaagtag gtaccttgcg gtttcatgac
    48421 cttgatttta gtctcttttc caaatagatc caccacataa ttgatgtggt cttcaaagac
    48481 ttgcttgagt tcctctagcc aatctttacc gtatcgatag gcagcttctg tcgccaaata
    48541 acccaagcct gaaatttcat gctgattatt ggccaacagg cgtttctgga aagccagtct
    48601 caacttagga ttttcaatga ctgcatagga attttttgtt ccagcaatat taaatgtttt
    48661 agtggcactg ctcaagacga tagcaaaatt tttgaaggca ggattgatgg tattgaaaga
    48721 ctggtgtttg tgaccaaaga gggtcaaatc ttggtgaatc tcatccgaaa ctaacaaaac
    48781 accgtgtttt tggcagagtt ggccaatctt ctccaacact tctttttccc aaacacgtcc
    48841 accaggattg tgagggttgc aaagaacata gagtttaacc tcctcttcca ccaaatcctt
    48901 ttcaagttgg tcaaagtcaa tctcaaacag actatccttt tccactaagg aattagtaat
    48961 caatctacga ttattcaact tgacactgcg agcaaagggt gggtagacag gcgtgttaat
    49021 taaaaccgcc tcgccttctt ttgtaaaggt ttgaatagct gttgagatgg ctggtaccac
    49081 accctcgata aagacaagag cctctttgtc aaagttgtaa ccgtattgtg tagcttccca
    49141 cttttgaact tccttaatta agtcttcact ggcataggta taaccataaa ccagttggtc
    49201 tgcgtaagtt tgcacggctt ggtggatttc aggcaagact acaaagtcca tatccgctat
    49261 ccaagctggt agaacttcac tatccgtttc tgtttctttc catttatagg tatggtgccc
    49321 taaacggttg ggcaggcttg taaaatcata ttttcccatc tttgtcttat ccttctaagg
    49381 cttggcgcaa atctgcaatc aaatctctag catcctcaat cccaatagac aaacgcaaga
    49441 ggtcatctgt caaaccataa gaatggcgta cttctgctgg aatatcagca tgagtttgag
    49501 tcgttggata agtaataaga ctttccactc cacccaaact ttccgcaaaa gagaagacct
    49561 tgagactgtt caaaatatga ggaatgcgtg tttcatcggc tactttaaag gaaatcatgc
    49621 ctccacgacc agtgtagaga acttccttaa ctgctggaga atccttcaaa aaggcaacca
    49681 cttcttgggc gttagctgtt gagcgctcca tacgaagaga caaggtcttg agaccacgaa
    49741 gcaactggta gctgtcaaat ggagacaaga ctgcccctgt tgtattaaga ttgtaaaaaa
    49801 gcttctcgta tagttctaaa ctattggtca caaccactcc agccaagaca tcattgtggc
    49861 ctgctagata cttggttgct gaatggagaa cgatatctgc tccatcttca atcggacgtt
    49921 ggtagatagg gctatagaag gtattgtcca ccaccacttt ggcaccctta gcatgagcca
    49981 attttgctag tttttcgata tcaaattcca acatcaaggg attggttggg gtttcgatat
    50041 agagaacatc cacatccttt tctaactcgg caatcaactc ttcttctgta ttggcatagg
    50101 taaaatggaa atgaccttcc tgctccactt ggttaaacca gcgaaaagaa ccaccgtaaa
    50161 gatcacgcac tgccaagacc ttacttccta ctggaaagac gctaaaggcc agtacaatag
    50221 ctgacatccc tgagctagtc gctagggcat agtctgctga ctcaatagcc gccaagactt
    50281 cctcagcctt actacgagtt ggatttttag tgcgcgtata gtcaaaccca gtagatcgac
    50341 caaactctgg atgctgatag gtcgttgaaa aatgaagtgg tgtcaccaaa gcacctgttg
    50401 cctcatcaga cttgatccct gcttgtgcta aaattgtgtt aatgtgtaat tccttgctca
    50461 tacaattcct ccaaatctat agtaactatt gtaccactta ttttcatcaa ctcattttct
    50521 tcttttcaag agctagttat agtttcaaac tatataaaaa gggagttttt cctgctccct
    50581 ttaatagact ataaaatggt gaatctcaaa agacaccttc actctatcat ttgctcctgc
    50641 acaaaacgag cataacgctc atgattttcc agtagttcct tatgagttcc tgagccagtg
    50701 attttcccct cctctaagaa gaaaatacaa tccacatctt ttaccgttga caagcgatgc
    50761 gctataatca caaccgtctt ctcctttagt acagaataga ggctactgat aatcgcatac
    50821 tcagaatccg catcaagatt agcagtggct tcatcaaata taagaatttc agcatctttt
    50881 aagtaggctc tagctatttg aagtctttgg cttcgccccc ctgacaagag tcgtccgcgt
    50941 tcaccaactt cagtatctag tccctctttc atggagcgaa tctcatcacc tagtgatact
    51001 aagtctagca ctttcatcaa ttcatcatca gttactaagc gattcaaacc gagacaaaga
    51061 ttgtcacgaa tactgccaga taagactgca ttattttgtg aaacccaagc gattttactt
    51121 ctccattctt ttaagttaaa atcatatata cttgattgct ccattagaat atctcctgaa
    51181 agcggtttat aaaaccgctc taataaacgc acaatcgttg attttcctga tccagatggc
    51241 ccaacaaaag caattttttg ccccttgaaa attgaacaag taatatcctt taagacaggt
    51301 cgattttcat cataaccaaa atagacatgg ttaaaattca acccttgtcc tgataccgat
    51361 tttcctccct caaatttttc tttaggaact gcaagcaagt tctccagtgc aactgaagat
    51421 cccttgctac tagaataaat agttacaaaa ttagctatat tactaatagg attaagtaat
    51481 tgaaagaggt aaatcaaaaa cgaaaccaag gttcccacag atatatatcc tgcgctgacc
    51541 cgataacccc cataggttag catcacaact atagtcgcaa agataaataa gagagcaaac
    51601 ggggtctcaa aagaagtaac cctatctgat ttcagtgaat tgttttgtac cctttcaata
    51661 caattatcca aaacatcctg tacacttttc tctgcttggt tagtcttaat taattcatgt
    51721 tcttgaatct tttcagtcaa ttgccctgtt aaaaatccga tttcctcctg taaacgacga
    51781 ctatactttt cactgatatt ggaaaggggc aagataataa acatcataca aggaagagtg
    51841 atgaataaaa gtagagaaag attccaatca agactaaata agactacaat ggaaccaagt
    51901 accataacta aactcagaat aatatttggg aaagtcgtaa ttaaaaactc acgaatgaca
    51961 ctcgtgtcat tgacaatggc agaagtcaac tccccacttt ggctcttatc aaagaagtat
    52021 ttctctgcat aaatcaaccc ctctatcact tttttcctga tttttgctat ctttttttca
    52081 cccgattgac taaacagata gtaaccaata gaagaaaaca aggcttgacc aataaaaatc
    52141 aaaaacgatt gaaatacttt ggaacctata ttttcaatag aactcccatc tattaaaccc
    52201 tttaagataa ggggaagcaa caaagcaagt agactagaca gaacaagtaa gaaactcccc
    52261 ataatcacct tagtatctac tcttaataat tttaatttca taaatactcc ttataatatt
    52321 tcaacggata aagtcgggaa taactcaatt tgaggataaa atctaataaa tcttcctata
    52381 acaaaacgca taacatctag gattttatat acctgatatt atgcgttttt aagcacaaag
    52441 acttcttaca caaacttatc tacaattaga ttttatttga catgttttgc caattcttct
    52501 tgggcttttt tattggattc ttctttttct ttcaaccatt tttctctggc ttttgcatat
    52561 tcgtctgttg tgacaatctt atcttgtact ttgaggtatt tatatgattc aacccctttt
    52621 gtaccggtta aaccataggc agcagcaaat ggtacggttc ttctcaatga tggtgttccc
    52681 ccacgcgaaa cacttggaag aactaaagaa ctatcaatca accaagcttg aatatcagca
    52741 tatttctcat aacgtttggc tggatcttgc tctttattag cttcttccaa catttgagta
    52801 tagacatcca gtccaacttc cttagccttg tcattggctt ctccaggctc tagtccaaga
    52861 ttttgtagaa ctcctccact attagtatta aaaatatcga gataggttga cgggtcttga
    52921 taatcaggtc cccaaccgcc atgatataaa tcatagtctt tctgagcagc tgtttgagca
    52981 aagtagcctg aactgtcaaa ctcatctgat gttaattgct gaatgtcaat cactacatta
    53041 tcagaaccta aaacagattc aattgattgt ttgatagaac taactccttg tatgcctact
    53101 ttatctgtta cttccacagt cttatccaag tggattggga attgaacacc ctttgcttcg
    53161 agttctttct tagcttccgc aaacttagcc ttggctttct caggattgta gtaagggtct
    53221 tgaccatccg caaagttgat accttgccat tccttaccat agttgaccat cttagaggct
    53281 acaacttcac caaagtcttt tcccttgata ctgacaaagt ttggaggaac cactaggtta
    53341 cgcaaaatct ttgttgcacc ttctttccct tcagactgag ccccataaga tgttctgtca
    53401 aaagcaaaat tgatagcctg acggaagttt ttattgagaa ctgcttcctg agtcgatttc
    53461 ttttcaatgt cacttgtttt agaagtataa ttgtaagact tcctatctag gttaaaatta
    53521 aagaaatatg aagttgaatt ttgcatacta tagatgatat tgtttttgta tttttcttta
    53581 atcccttcat agctggagct gttaggaaaa agacgagccg tagtataagc accagctgta
    53641 aaattacgtt ccagtgattc ttggtcgcta ccatcatagt aggtcaattt cacatcgtct
    53701 acaaagacat tcttagcatc ccagtaatta gggtttttct tatattcaat agcagatttt
    53761 gagacaagtg ctttcatcaa gaaaggtcca ttgtacaaaa tactagatgg atccgccttc
    53821 ccaaaatcat ccccttttga tttcaggaaa tctgcattaa caggaaaaag tatcgttgca
    53881 agtgtttttg aattccagta aagttctggt ttaaccaaag tatattgaac cgtttggtca
    53941 tcaagtgcct tgacaccgac agttgaaaag tcgcttgttt taccagtgat atagtcatcc
    54001 aaaccagcaa cagagtcctg cactagatac aaagcttctg attttttatc agctgcatat
    54061 tgcaaacctg tcacaaaatc ctgggcagtt acaggcgcat attcttctcc ctcagaagta
    54121 aaccacttgg catccttacg aagtttgtag gtataggtca aaccgtcctg agaaacagtc
    54181 caatcctctg ctaatgatgg aataatattc ccatattggt cattttctaa taacccgtct
    54241 accaaatttg caacaatatc ggatgttgct gcgcggtttt ctgctagata gttcaaacta
    54301 gatggatcac ttgaataaac atagttatag gtttttgatg cagtgctaga atttccacac
    54361 gcgctcaata aaactcctgt acccaggaca agacctgcca aggttagata tttgctctta
    54421 gactttttca tttccagaac ctcctgcttt aaatatttgt tttattatac aactcttggt
    54481 ttgtttagtc aattgttttt tccaaaaaat caaaaaaacc tcattttcta tttttgaaag
    54541 ataattttag ctattttgac gctaaaaaag gaataagttt caagttctcc taaaagattg
    54601 ttcaacttat tccttttatt tataaatgct accttacgaa agcttaaatt ttgctcgcag
    54661 gcgatctgct tgggcttttc ctattacctt atctaataaa taggtacgca gactcataac
    54721 catataaagt ccacccccca tggcaccgac aagagctaca taaaagaagc tccacaaacg
    54781 tccacttggt tggaagaaaa atcctaacag ccactggatg gttcctatta acagaaacat
    54841 gactagggtc agcaaactga ttaaaatggt tcgcttcaaa atcaccttgc gcttgacacc
    54901 agttacttta caaatatccc gatacatcaa gacgttagga atgatgagag caatggttgt
    54961 tgaaatcaaa ggaccataac tgtggaagag ggcgatggta ggtagttgca agactagctt
    55021 ggcaatagaa ccatagataa aatagagaac ggccttgcgg ttgcggaaca tggcctgaag
    55081 cattggagac aagaccatgt acaagcctaa aataatagac tgcaaaactg caaagacaaa
    55141 taagcccaga gccaaactat ctggcttacc atagaagact gtatatagag gttctcctac
    55201 cataaccact ccaaccgttg ctggtagcaa gaacataaag agtagggtga gactgtcctg
    55261 aaccagacga gaagctgctt tcaagtcccc cttgacatag ttttccgtca aaagtggcaa
    55321 accaacactc ccaatcgaaa cccctacaga aatcaaaatc atcgtgattt tattaggatt
    55381 ggctgagaaa taagaaaaca tgacaaccaa gtcctcattg ctgtagttgg taaaccagct
    55441 catactattg ataaaggtca gctgatccaa aatctggaag agctggatgg cagaccctgt
    55501 caggataaaa ggaatggctt ccttaatggt atcaaccaag agacgcttac tgttaatctt
    55561 atctcctgtt tcaaagactc ttttgagtga accttcttgg gcaaggaaat aaatcaagac
    55621 tgcaaaactg gctaccatac cgacaaaggc agcaaaggtt gattgggtaa cggctgctag
    55681 ataatctcct gaaccgagct tcataatgat aaaggttgct aggagcatcc agataacacg
    55741 aatgacctgc tcagcaattt ggctcatggc ataaggtttg aggttattca tcccttggaa
    55801 aaatcctcgg ataacactca tagacgggaa aatcaagact ccccaagcca agctttgcat
    55861 gattgggatc aagtctttgc ccacgccaga caagtctgct agccaaggag caaagacata
    55921 caagactaaa gcaaaaacca ggcctagtcc tgtcataaag cctaagaagc tccgaatcag
    55981 ggcaaagcta tgctcttctt ctcgcatggt attatacttg gcaacttgct tggccaccgc
    56041 aactggaatc cccgctgttg aaaccaacaa gaaccaagca tagatattgt aacccatggt
    56101 aaagagacca tttgccttag ctgcataagc ccccatccag atgtaccaag ggataatgta
    56161 aacagccccg agtaggcgac tgataaagtt actagccgtt agccaagcag tcccccgtaa
    56221 catctgggcc tgctggtgat tgttttcgtg cgacatagat tcctcattca attttgataa
    56281 ctaggaaaaa ctccttatct tccattataa acttttcctt gttacttgta aatttgcgac
    56341 tttcggttta caatagaaag tatgataaaa attgaaactg tattagatat tttaaagaaa
    56401 gatggccttt ttcgcgaaat tattgaccaa ggtcattacc actacaacta cagcaaagtt
    56461 gtttttgata gcatcagcta cgatagccga aaagtaacag aagacactct tttttttgca
    56521 aaaggcgctg cctttaaaaa agaatacctt ctttctgcta taacacaagg cttagcttgg
    56581 tatgtagctg aaaaggacta cgaagtcggt atccctgtca tcattgtgaa cgatataaag
    56641 aaagccatga gtttgattgc catggagttc tatggtaatc cacaggaaaa actcaaactc
    56701 cttgccttta ctggtactaa gggtaagaca acagcagcct atttcgccta taacatctta
    56761 tctcaagggc atcgacctgc tatgttgtcg accatgaaca caactcttga tggcgagact
    56821 ttctttaagt cagcgttgac aacccctgag agtattgacc tctttgacat gatgaatcag
    56881 gctgtgcaaa atgaccgtac ccacctcatc atggaagtct ccagtcaatc ctatctggtc
    56941 agacgtgtct atggtctaac ctttgatgtg ggagttttcc tcaatatcag cccagaccat
    57001 atcggcccga ttgaacaccc tagctttgaa gactatttct accacaagcg tctcttgatg
    57061 gaaaatagcc gagcagtcat cattaacagt gacatggacc acttctcagt cttgaaagaa
    57121 caggttgaag atcaagacca tgatttctat ggtagccaat ttgataacca aatcgagaat
    57181 tccaaagcct ttagcttttc agctacgggt aaactcgctg gagattatga tatccaactc
    57241 attggcaact tcaaccaaga aaatgcagtt gctgctggac ttgcttgtct ccgtctcgga
    57301 gcaagtcttg aggacatcaa aaaaggcatc gctgcaaccc gcgttcctgg tcgtatggaa
    57361 gtcctcactc agaaaaatgg agccaaggtc ttcatcgact atgcccacaa tggggatagt
    57421 ctgaaaaaac tcatcaatgt ggttgaaact catcaaaccg gaaagattgc tctggttctg
    57481 ggatcaacag gaaacaaggg agaaagtcgt cgtaaggact ttggcctcct cctcaatcaa
    57541 caccctgaga ttcaagtctt tctgactgct gatgacccta actatgaaga cccaatggcc
    57601 attgcagatg aaattagtag ctacatcaat catcctgttg agaagattgc ggatcgccaa
    57661 gaagccatca aggcggcaat ggctatcaca aatcacgaat tagatgcagt tattattgcg
    57721 ggtaagggag ccgattgtta ccaaatcatc cagggcaaga aagaatccta cccaggagat
    57781 acagccgtcg cagaaaatta tttataagaa tagaaaaaat caagggaaaa tgaaaccctt
    57841 gattttttcc tattctttag taaaaacgtt tttcaaacct tcaacggcac cttctacagc
    57901 accttttgcg tcttctacaa cgtcttttgc cttagcaact gttttttcaa cagctccttc
    57961 aagttctgtc ttgctgtctc cagtaacttt accaaaacct tctttgacag cgcctgttgc
    58021 ttgttccaat ttgttttcaa gtgacatatg attgtctcct ttagtttatt ccgatatgtg
    58081 ttaccggtta catatagttt ataccgaata ctaaggaaag tcaaacaatg tactcagaaa
    58141 caagaaatca cgctaagtag aaagttaatc tctccttatc aaaatcgata gccaactcat
    58201 actttccatc ttcattttgc acaatatagc ctaagacaac caaactgtcc acaaagatat
    58261 cacggcattt ctgcataagc tggtcttttt tgagaaattt caacaaaaaa gccgtcatat
    58321 acttgagtgc atactcagga ttaacatctc ctaaaatgtc atagagctcc tgctgttttt
    58381 ctgtcaaagg atactgctgt ttgaccttgt aaaaataatt ggacagggtc attttaatgc
    58441 gcgcaaagtc cgtcttttca actaaaatag ctgcattgat ttgattgcgc aattccgtct
    58501 caaaactctg ctccaacaag gcttgataga ccggactagc ttctctgaca aaaatctctt
    58561 gatccagttc aagactatca agtgattcaa gcgtaggaaa attgaggtaa tagcgcttat
    58621 tttcacgtag aatcaagcct gcctttatat actcttccat gagtttatca actgcaacat
    58681 ctggaaattg agccttaatt tcccgtagaa tcacatcctc atactggtcc agatagcgga
    58741 tcaattctcc aaaaatggct gtctcgtcaa acgagatgga ttaaaaatct gaatcatgaa
    58801 gattcctttc tttacattgt aacagaggcg atgctgccaa ctgactagga ttggtaccag
    58861 cttggttcag aggaacaggc agacctagtt ctatgtaata ctccctccaa aaatcactaa
    58921 tctcctgctc cccatctcca aatttcatag gaatagtttc aaaaataggt aggatttctg
    58981 ctatatactg ggagcagtag aaaccaggtg catctggata gaaagaagca ttgtagggtg
    59041 ctccaagatg tttgcaagct ctttccttca ccgactggat atccatttct ggataaacat
    59101 agaggtcgta caaatgattg gactcaaaga agtctgccgg ttcttgacag acaacaccag
    59161 cctgtccact agcatgataa atcatcccat ccaaataaat ggcaacatgg ctatagttac
    59221 ctgtggaagt ctggatggcc tgtcccatgt ctgacccatc tctcacaaaa atcaaatcgc
    59281 cattttctaa catacttcac tcctagaaaa aaaggagccg aaactccttt cgatataagg
    59341 caaactagac tttccgattt tgagctgaca cccaaaatct tacgcattaa agctttcagt
    59401 taattgaggt accacttgtt tcttacgtga aacggcacca gcaaggaagg catgattgtt
    59461 ttcaagtttg aagttgaaag ccgcttcgac cttgtccata ttggcaccaa gagccaagat
    59521 ttctgagttt gagttgacga tatctgtaat catcaagaca aagtcagagt agccgtttga
    59581 ttcgttggca gcttgcattg cagcttcaat ttctgcttgg cgttccaaaa cttcagcgat
    59641 gtcaactgtg ttcacttggg caacacggac attatttccg ttgagttcaa aagtcttagc
    59701 atcgatgtca atcaattctt cagcagattt gctagccaag ttggtaccag ctttcaacat
    59761 tgccaaacca tattcttcca agttcacacc agccaattca gccaattcag gagcaatgat
    59821 tttatctgtt gggtgtgttg ttggtgattt caaaagaagg gtatctgaaa tcaaacctga
    59881 aagcatcaaa cctgcaatct ctttaggcac agctacacca tgttctttga acatacggta
    59941 aacgattgaa gacgctgatc caactggctc caaacgcatg taaagtgggc ttgcagtttc
    60001 aaagttagcc acacggtggt ggtctacaac accgtaaact tctacttcag cgatatctga
    60061 tacagattgt tggaattcat tgtggtcagt caagataact tgctctgctc cctctgcttt
    60121 ggcagaagtg ataacacgtg gtgcttctac accaaaatag ttcaagacaa aggctgtttc
    60181 ttcatttgga gttccaaggg caacagcttc cgtatccaaa ccgtaagctt cttttgcaag
    60241 gtaggcaaaa gctacagatg atccgatggc atctgagtct ggattttggt gaccaaatac
    60301 tagaatcttg gacatgataa tacctcattt tgtttatttt ctttattgta gcattttttt
    60361 cgctttttga caaaggtaag aggagtcaaa ggactcccca cgattcttca aaataactga
    60421 gtaaatttct atcttgattt tcagataaaa attcttcctt ctgtggcctc ttcttacgct
    60481 tgagaagagc ttcagccgac atggcttctt ccttactggc aaaaccttga gcatagataa
    60541 gtttgactgg caagcgtgct cgtgtatatt tggctccctt cccactattg tggatagcga
    60601 ggcgtcttct cacatcagtc gtatagccta tatagtagga tccatcacga cactccagaa
    60661 cgtacatata agccttatga tccataataa atctcttcga tttcgggcgt ataagagcca
    60721 tcatcattgt ggacaatcaa aggaggtaag accttaaagc cacttgttga gccatccttg
    60781 atcgcctcaa tcaaaagcat attggcttcc ttttctcttt ttggataaac aaactgcagg
    60841 cgcttagggg ctagattatg tcgttttaac gtatccaaaa tatccagaag tcgatcagga
    60901 cgatgaacca tggccaaacg cccattagac ttgagaatac tctgggcact acgacagatt
    60961 tcttccaaat tagtcgtgat ttcgtgtcga gccaagaggt aatgttcact ctcgttcaga
    61021 ttagaataag gatccacctt gaaatagggt ggattacaca aaatcatatc caccttactc
    61081 ccctgaatgt gagcaggcat atttttcaaa tcatcgcaga tgacctgcat ttgctcctct
    61141 aatccattca aacggacaga gcgttcagcc atatccgcca aacgctcctg aatctcaaca
    61201 gacaatatct gtgcttgagt acgagtgcta gcaaaaagcc ccactgctcc attcccagca
    61261 cagaaatcca caatcagccc cttcttagga aaacgtggaa atcgtgataa gagaacacta
    61321 tccaccgaat agctaaaaac ctctctattt tgaatgattt tgatatctgt cgaaaagagc
    61381 tggttaatgc gctctcctga ttttaataat tgttcttctt ccatggtcct attatagcaa
    61441 atttatatta acattacaaa aaatataaaa ctctaaacta cttcttcttt tttaaatggt
    61501 gcagggcttc tccagtccag attggtaaca ttcgtcgaaa gggagcaaaa ccgtagttaa
    61561 agcggtcgct tgaaaagcgt ctccgtctag gaaactggta cttttcttcc tccaaagtgc
    61621 ggatagaaag actggctttc cccgtaaatt catctaaatc cactacctga acttgaacct
    61681 cttcatcgac tttcaaggtt tcatgaatat tttcaataaa tcctgtccga atttctgaaa
    61741 tgtgaatcag ccccgtatca cccgtctcta actcaacaaa ggcaccgtag ggctgaatcc
    61801 ctgtaatacg cccctttagc ttatcaccga ttttcatctt agtcctcgat ttcaatagtt
    61861 tcaattacaa catcttcaac tggcttgtcc atagctcctg tctcaacagc agcaatggca
    61921 tccaagacag cgtaagatgc ttcatcagct aactgaccaa aaaccgtgtg acggcggtct
    61981 aggtgaggtg tcccaccttg attggcatag atttctgcaa tcggttctgg ccaaccacca
    62041 cgagtaattt ctttcttcga ataaggtagg tgttggtttt gcacgataaa gaactggctg
    62101 ccgttggtat ttggaccagc atttgccatg gaaagagcac cacggatatt gtaaagctct
    62161 tctgagaatt catcctcaaa agattcgccg tagattgact cgccacccat accagttcca
    62221 gttgggtctc caccttggat cataaagtcc ttgataatac ggtggaaaat gacaccatca
    62281 tagtagccat cttttgaaag agatacaaag ttagccactg ttttaggagc atgttcaggg
    62341 aaaagcttga tacgtaagtc tccgtgattg gtcttaatag tcgcaagagg accttctact
    62401 gtttcaatgt ctacttgtgg aaaatgcaat tctttttcta ccataccaaa tacttctaag
    62461 gcagcaaaaa tgccatcttc ttctaatgtt tttgtaatat aatctgcttt ttctttgatt
    62521 ttatcatgag aaattcccat ggcaacgctg attccagcat aatcaaagag ttccaagtca
    62581 ttgagaccat ctccaaaaac catgaccttc tctggtttca agccaaggtg ttccacaacc
    62641 ttttccaccc ccgtcgcttt ggagcctgaa atcggcacaa tatcagacga atgttgatgc
    62701 caacgaacca tgcgaagttt gtctgagaga ctgtcaggca agtgcaagtc atctccctta
    62761 tcttcaaaag tccacatctg atagatatct tctttttcat ggaaatcggg atctacatct
    62821 aagtcgggat aaattggatt gatagcttca ctcatcatat cggtgcgagt cgacaacttg
    62881 gcatcatgac tcccaaccaa gccatactca attccttctt gcttagccca agagatatac
    62941 tcctcaacat ctgacttttc aatctgatgc tgataaatga cctgaccttt tttatcttcg
    63001 atataagccc cattcaaagt tacaaaaaag tcaggcttga gatcacgaat ctctggaaca
    63061 acaccaaaaa tgccacgtcc agaggcgatt cctgttaaaa ttcctttttc acgcaactgt
    63121 ttaaaaacag tgggaattgt agttggaata aaccctgtct ttgaattccg caatgtatca
    63181 tcaatatcaa aaaagacaat cttgatcttc tttgccttgt atcttaattt cgcgtccatc
    63241 tcactacctc tttcaatcta actctttcca ttatatcata aagtaggcaa atcccctatt
    63301 ttcaaaaagt ttatcatttt tattttaatt tcttggatga gaaaaaagac atatttatga
    63361 aaaagctcca tcgtgctttt aatgtgttct cttgttttca aactcgtaaa aagggagcca
    63421 ctgagcctga ctcgctctct catttcaaag cttgtgaaaa aagacccgtt ggggtcttaa
    63481 ttcgctttct tgttttcaag ctcatgaaaa agagacccaa ccgggtcttt tctttaatct
    63541 tcgtttacga aaggcatcaa agccattacg cgagcgcgtt tgatagctgt tgttacttta
    63601 cgttggtttt tagctgaagt tcctgttaca cgacgaggaa ggattttccc acgttctgaa
    63661 acgaaacggc taagaagctc agtatctttg taatcaacat attcaatttt gtttgctgcg
    63721 atgtaatcaa cttttttacg gcgtttgaat ccgccacgac gttgttgagc catgtttttt
    63781 ctcctttata agtttagttg tccattagaa tggtaaatca tcatctgaaa tatccaatgg
    63841 gtttgttgct ccaaatggat tttcattacg tgaaaagtct ggtactgaat ttgtaggtgc
    63901 tgaatagttt gcagttggtg cagagtaagc tccacctgtg tgaccctcac gcacactacg
    63961 gctttccaac atttggaaat tctcagccac gacctctgtc acgtagacac gttgtccttg
    64021 ctggttatcg taactacgag tctggatacg acctgtcacc ccgataagtg agcctttttt
    64081 agcccagtta gcaagatttt cagcctgttg gcgccacata acgacattga taaaatcagc
    64141 ctcacgttca ccattttgac tcttaaatgt acggtttact gcaagagtaa aagtcgcaac
    64201 tgctacattt gatggggtat aacgcaactc agcgtcacgt gtcatacgcc ctacaagtac
    64261 aacattgtta atcatagttt accttcttac gcgtcaattt tgacgatcat gtgacgaaga
    64321 atgtcagcgt tgatttttga aagacggtca aactctttaa gagctgcatc gtcatttgct
    64381 tcaacgttaa cgatgtggta aagtccttca cggaaatctt ggatttcgta tgcaagacga
    64441 cgtttttccc aagtttttga ttcaacaaca gttgcaccgt tgtcagtcaa aatagagtca
    64501 aaacgtgcta ccaaagcgtt tttagcttct tcttcaatgt ttggacgaat gatataaaga
    64561 atttcgtatt tagccattga tatgttcctc cttttggtct aatgacccca agactttgca
    64621 aggggtaagt gaggttcgct cacaataaac tattatacta gaaaaaattt ttttacgcaa
    64681 gtaaaaacac tagaattcga aaaaacgcca catgggcgtt ttcctgttct tatggtttga
    64741 tacggtgtaa catacgtggg aatggaatag cttcacggat atgttttgtt cctgctgcga
    64801 aggttaccat acgttcgata ccgataccaa atcctccgtg tggaactgta ccgtatttac
    64861 gaaggtcaag gtagaattca tattctgtac gatccatgcc aagttcatcc atcttagcga
    64921 caagggcatc gtaatcttcc tcacgcatag acccaccgat aatttctcca tagccttctg
    64981 gagcaagcaa gtctgcacaa agcacgcgct ctggatttcc aggaactggt ttcatgtaga
    65041 aggccttgat ggctgctgga tagttcatga caaatgttgg cacaccaaag tggtttgaaa
    65101 tccaagtttc gtgtggtgac ccaaagtcat caccatgctc aagatgctcg tagtcagcat
    65161 cttcatcatt ttcatgctct tgcaagaggt caatggcttg atcgtaagtg atacgtttga
    65221 atggctctgc aatgtagcgt ttcaagagtt ctgtatcacg ttccaaggtt tccaaggctt
    65281 gaggcgcgcg gtcaagaaca ccttgtagaa gagctttcac ataagcttct tgcaagtcaa
    65341 gcgactcatc atgtgtcaag tatgagtact cagcatccat catccagaac tcagtcaagt
    65401 gacggcgtgt ttttgatttt tcagcacgga aaactggacc aaagtcaaag acacgaccaa
    65461 gagccatagc ccctgcttct aggtaaagct gacctgattg gctcaagtag gctggcgttc
    65521 cgaagtagtc agtttcaaag agttctgtag aatcttctgc cgcatttcct gaaagaattg
    65581 ggctgtcaaa cttcataaaa ccgttcttgt caaagaactc ataagttgca tagataatag
    65641 cgttacggat ttgcaacaca gctacttgct tacgagagcg tagccacaag tgacggttat
    65701 ccatcaaaaa gtctgttccg tgttcttttg gtgtgattgg gtagtcttga gattcaccga
    65761 tcacttcgat gtctgtgatg tccaactcat agccaaattt agaacgttcg tcctctttga
    65821 caatacctgt cacataaaca gacgtttctt ggctcaagcg tttgataaca tcaaacttct
    65881 caagtcccac ttcttcacca aatttttcga caaagtttgg tttaaaagcc acaccttgaa
    65941 agaaggctgt tccatcacgc aattgtaaga aagcgatttt tccttttcct gatttgttgg
    66001 caacccaagc gccaatcgtc acttcctgac caacatagtc ttttacgtca ataatcgtta
    66061 cacgttttgt cattattttt ccttttcttt tttattcttt atggcaaacc acctctatat
    66121 tgttcccatc caggtcaatc ataaaagcag catagtaaat cggatgctca cttcgataac
    66181 caggaacccc attgtctcgc ccacctgcct ctatgccagc ctcataacaa gcctgaactt
    66241 cttccttatt ttctgctaaa aaagcaaaat gaacaggatc ttgtgttccc tgagtcagcc
    66301 aaaaatcacc accaggatga gggctgttcg gggatagaaa actaattaga gaactagtct
    66361 taaaagccaa tttatagtcc aaaggaacga gaaaactcct ataaaatcct tctaaaattt
    66421 gtaaatcctt taccttaatc tcaaaatgat caatcattct cactacccat aaatgctttc
    66481 aagcgttcga ctgcttcttt aagcgtgtct aggtctgtcg catagctgag gcggacattt
    66541 tctggtgctc caaatccagc tcctgttacc aaggccactt cggcttcttc taagataaca
    66601 gttgtaaagt ctgtcacatc cgtgtagcct ttcatctcca tggccttttt gacatttggg
    66661 aagagataga aggccccttg tggtttgacc acttcaaatc ctggcacctc tgcaaggagg
    66721 ggatagatgg tattaagacg ttcctcaaag gcctgacgca tgctttctac agtatcttgc
    66781 tcacctgata gagcctcaac tgctgcatat tgggctactg ctgacggatt cgaagttgtt
    66841 tgacctgcaa tcttggacat ggcagcgata atgtctgctt ctccaacggc ataaccaatc
    66901 cgccaaccag tcatggcata ggttttagac acaccattga tgaccactgt ttgcttgcga
    66961 atcgcttccg ataggctaga aatcggtgtg aactcatgac cattataaac caagcggcca
    67021 tagatatcat ctgctaggat gagaatatca ttttctacag cccagtttcc aattgccaag
    67081 agttcctcac gggtgtaaat catacctgtg ggattagatg gcgaattcag caccaaaacc
    67141 ttggtcttgt cagtgcgagc tgcttctaac tgctctacgg tcaccttaaa gtgattgtct
    67201 tccttagcag aaacaaagac gggaacgcct tctgccatct tgacctgatc tccatagcta
    67261 acccagtatg gggttgggat gatgacttca tcacctggat tgaccacagc cataaagaag
    67321 ctatagagag aatatttggc tcccgcagcg actgtcactt gatttgacgc tacagaatag
    67381 ccgtaaaagc gctcaaagta gctattgacc accgccttaa gctctggcag acctgaggtt
    67441 actgtataaa aagaagcacg cccatctcga atcgatgcaa tggcggcatc ttggatattt
    67501 ttgggagtag tgaaatctgg ctcacccaag gttagagaca aaatatctct accctcagcc
    67561 ttcagtgctt tggcacgggc tccagcagcc aaagtcacac tttcttccat ttctaaaaca
    67621 cggttggata gtttcatagg ccctccttgt tgaccaatgc tcctgtttca aaatctacta
    67681 gataaaaatc agatcctgac ttaacttccc agattggctt atcttgataa cggccaaagg
    67741 ttatcttgtc aatctcgcca gctccctttt ccttagaaac cgtttctgct ttttcttgtg
    67801 aaacaccctg atttagctga taaacgtaaa tcttatgatc atctttacca atcaggacag
    67861 caagcgcttc ttgctgttta ttacgaccaa gaacgctgta ataagattcc aagccattgt
    67921 ataaatcaac ctgatcgacc tgctctaatc ctgcatactg ctgagctaat ttttctcctt
    67981 cacttttagc tgtttgatag ggtttcatgc taagagaaac catatacaga aaggaagcac
    68041 tgataaccac aaacaaaatc gtcatcccta gaccatactg ccacagtaga ttattttttg
    68101 ctttgttttg tctttttttc actcgtctat tttaccatct attaagcttt attacaagtg
    68161 aatataagaa tactcttcga aaatctcttc aaaccacgtc agctttatct gcaacctcaa
    68221 agctgtgctt tgagcaacca attctatttc tcccttcaaa caaaaccgat tttgaaagtg
    68281 aaacagttct tactttttca gtcacaaatg actagagttt ccgaaatttt acaattttca
    68341 aataaactct gagcaaattt cttgcaagtt cttttgtttt gttgtaatat attttataac
    68401 aacgagagag ttctcgaaat tttaagaaaa aggagacaca tcatgtctaa aaaagtatta
    68461 tttatcgtcg gatcactacg tcaaggttct ttcaaccacc aaatggcgct cgaagctgag
    68521 aaagcacttg ctggtaaagc ggaagttagc taccttgatt attcagccct tcctctcttc
    68581 agccaagatt tggaagttcc aacacatcca gctgtagctg ctgctcgtga agcagttctc
    68641 gttgcggatg ctatctggat tttctctcca gtctacaact tctctatccc tggtacagtg
    68701 aaaaacttgc ttgactggct atctcgtgcc cttgacttgt ctgatacacg tggcgtttct
    68761 gcccttcaag acaagtttgt cacagtatca tctgtagcca atgcagggca cgatcaactt
    68821 ttcgctatct acaaagacct cttgccattt atccgtacac aaggcgttgg tgatttcact
    68881 gctgcacgtg ttaatgactc tgcctgggca gacggaaaat tggttcttga agaaacagtc
    68941 ctaaactcac ttgaaaaaca agctcaagac ttggtcgaag cgattcagta aaaaatagaa
    69001 aattttagaa agtctaaatc aattatagcc acctaatagg gtggcttttt atttctcaat
    69061 caagattttc agacaaacat cagccatcca aaaaaacctt gagcgttacc actcaaggtt
    69121 tttagcagtc ttttccatca taggaaaatc attctaagaa tattctttca ttcgagatct
    69181 atcacttatc atcttctttc gagaaattag tgactgcttt tggctgatta agcttctttt
    69241 cttcgtccta catataggct caatagaata ccgctaccta aaagaacaga gatataatca
    69301 gattggcttc cagtttcagg taatttgtcc ccacggtttt ctttacctgt agttggtgct
    69361 actgggttag catttactgg agttgctggt tgagccggtg ttggtactac tggttgttct
    69421 ggaaccgctg gtactggttt aaccggtact tctggtgttg gaacagctgg agttggttgt
    69481 actggcactt ctggtgtcgg tacatttggt gttggttgcg ctggcacagg tttaaccggt
    69541 acttctggtg tcggcacatt tggtgttgga ggaactggtt tgtcatttga tggtgttact
    69601 ggtttgtctt ggcatccaca ttttccatct ttaccgtctt taccgtcttt gccgtctcga
    69661 ccatcacgtc catctctacc atctttaata actgtttttg tcacagttcc atcagaattg
    69721 atgattgtga ttgtatgact accatcacca ttatcttcaa cagaaacttt tggtgattta
    69781 ccatctttac cgtctttaat caccatttct gtcttacttc catctggatt agtgattgta
    69841 acaacgtgag ttccatagtt attattttta acagttacag ttggtgaaac gctatcttta
    69901 ccgtctttac catctttgat aatagatttg tattcacgac catcagaatc tacgattgtt
    69961 aatgtatgag ttccatctcc gttatcaacg atgttcgctt ttggtgattt accatcaaag
    70021 attgtagttg tcgttccttt accatcagca cctgtcactt taatagtgtg tgaaccatcg
    70081 ttgttatcaa taacttcaag ttttggttct ctaccatcac gaactgtagt tgttgtagtt
    70141 gttccgtcac catttagaac agagatctta tgagttccat tttgttcatc agttatagtc
    70201 acttttggtg atttaccatc acgaactgtg gtttcagttg tcacaccttc tggatttgta
    70261 ataacgattg tatgacttcc gtctccatta tcacgaacag atgcggttgg agtacgtccg
    70321 tcaacaccgt cacgtccatt cttaacaaca aactcattct tagttccgtc tgggttagtg
    70381 attgttactg tgtggcttcc atctggattt tcagtagttg ttgctgttgc agctttaccg
    70441 tctttaccat ctttgatgat agcgttggta acattgccgt ctccatctgt aactttaaca
    70501 gtatgagttc catcgttgtt atccgttact tcaactttag gagtcttacc gtctttaccg
    70561 tttttaacaa cagtttcttt agttgaacca tctggatttg tcaccgtaat tgtgtggctt
    70621 ccatctgggt tttctgttgt agtgatattc gcagttttac cgtctttacc atctttaaca
    70681 actgttgttg attcagaacc atctgggttt tgaactgtga tagtgtgagt tccatctcca
    70741 ttatcttttg tagtaatagt tggagctgaa ccatcacgtc catctatacc gttataaata
    70801 tctttactat ttaatacttt atcgacacct tcgtcgtata ccccattgtc attaacatca
    70861 tcataaactg taacacggat accgttacgc gttggagttg cagcagcatc tgtatcgcgt
    70921 ctaattcttg aaggtgaagt aatatcttct actttgattt tcggtgcacg gccatcttta
    70981 ccattcttac catcttttac agtgaaggtt actggatctt tacctgatgt tgtgatagtt
    71041 acaacagtgc tttggccatc ttgtccacgt tgagtagtga ttgtaggagt ttgtccatcc
    71101 tgaccggttg caccagtttc tcccttagca ccatcttgaa caaagactgt agttggttgt
    71161 gaaccatcat ggttatcaac agtgatttct acacctttat gccctgcttc atctttacga
    71221 acagctgtaa ctgtaggtga ttttccatct actccatctc taattaccgc aagtggtttt
    71281 tctggattta atggttgtcc tgggttagct ggatcttctt ggtaaacttt agtttcttta
    71341 ccatccttga cagtaagcaa tgatttacca tctcgtccgt ccgcgccttt agcaccatct
    71401 ttaatcattt ctgaacctag aagttcatca gttcctggtg tatatttgcc gtcattgttt
    71461 tcatctgtat agaatgtcac aattgtatga gatggatttc cgttttttcc ttggacacga
    71521 agtaaatcaa cttttggagt tttaccgttc agaccatttt ctccgtcctt aacatttact
    71581 gtaactggat ctttacctgg aacagtgaat gtaatgtcag tactatggcc atctttacct
    71641 ggagttacag ttacttctgg agtcttacca tcttctccgc gttcaccttt gtcaccctta
    71701 gggcctttga tgttgccctc tttatcccag ttgccgttat tcttaacgaa gacgtcgcct
    71761 gtttctgtat taacgtattt atcgccgtct ttaccttgat gtgcttctgg gttagctttg
    71821 ccgttcaaca cgtctttacc gtcacgtcca tcacgaccta ctgcgccatc cgcaccttta
    71881 gctccttgag ctccagttag gccgcgttca ccttgggctc ctttttcacc tttagcacct
    71941 tgtgcacctt tgtcaccttt agggcctttg atgttgcctt ctttatccca gtttccattg
    72001 tttttaacat agacatcacc ggtttcggta ttaatatatt tatctccatt tttaccttgg
    72061 tttggttgtg gatttacttt tccgtttaat acatctttac catcacgacc tgcttgtcct
    72121 gtagctccat cacggatcgt agttgtcaca tctggacttc ctggattatg aaccgttaat
    72181 gtatgtgtgc cgttttgccc ctcagttatt gttactgttg gagttttccc atcagcaccc
    72241 ttttgtccat cctctacaaa tgttgtttgt ggacgacctt ctactggtgt aattgttact
    72301 aatacaccat ttttgccatt ttgcacactt cgtgtcgctg taattgttgg tgattgtcca
    72361 ttagtaccgt ttcttccatc agtgatagtt gctaatggtt ggtttggatt aagtggttgt
    72421 cctggtctag ccggatcctc tacatagact tttgtttcag ttccattttt aacagcaatt
    72481 agagattttc catctttacc tggagttcct ggattacctt gttctccttt tggtccttgt
    72541 ggtcccgctg gtcctctttg tccatctgcg ccttttggtc cttgagctcc atcacgacct
    72601 tgaagacctt gttcaccttt gtcacctttg gcaccttgcg ctccagttaa accgcgttca
    72661 ccttggtctc ctttttcacc tttagatcca gttagaccgc gttcaccctg atctcccttt
    72721 tcacccttga caccttgcgc tccagtcagg ccgcgttctc cttgggctcc tttttcaccc
    72781 ttggcaccat ctgcaccttt gtcacctttc ggtcctttga tgtttcctgc tggttcccaa
    72841 gtgttacctt tcttaacgaa tacatctcct gtttgtgtat ttacgaatgt gtctccatct
    72901 ttaccttctg ttgttgggtc tacttttccg tttaatactt cttttccatc acgtccagat
    72961 gctcctgcag ctccgtcttg tccgtcttta actactgttg tttgaactaa ctcgtctttt
    73021 cctgctgtgt aacttccatc tccatctttg tcaatgtaga atgttaatgt tgtttgtttc
    73081 ttcgcatcat ctcgttctgc tttgactttt ggtgtttttc catcttcacc gtttttaacg
    73141 attgttgtta atgatggtct gttgtctggt tgtgtgattg tgatggtgtg tgttccgtta
    73201 ttgttatctg taactgttac ttctggtgtg aatccatctt ttccgttatc acctttgtca
    73261 ccttttggtc cttgttttcc atctgcgata acaacttctt taagttttgt atctccttca
    73321 tcaaattgat tattatcatt tagatcataa tagaaaataa cagttgttgt tttatctgct
    73381 tcatttctat gagtagaaac aagagggctt gcaccatcaa atccatctct tactactgta
    73441 gtagttatac cacctttacc atcgttaatt gtaattgtat gcgttccatc ttgaccatca
    73501 gttactttaa ctgttggggt tttcccatct tctccttttg gtccttgttc accatcacgc
    73561 ccttgaagac cttgttcacc tttgtcccct ttttcacctt tagcaccatc tgcaattaca
    73621 acttctttta atttcttatc agaagcatct aattcattgt ttccattttt atcgtaatag
    73681 aagataacag ttgttgtctt atctgcgtca tttcgttgag tcgcaactaa tggacttgcg
    73741 ccatcgaaac catctcttac aacagtactt gtaacattac ctctaccgtc gttaatagtg
    73801 atagtatgag tgccgtcatt tttattatct ttaacggtta cggttggagt tacaccgtca
    73861 cgacctgcct gaccttgggc tcctttttca cctttagctc cagttaaacc acgttcgcct
    73921 cggtctcctt tttcaccttg ggctccagtg agaccgcgtt caccttggtc ccctttttca
    73981 cctttagctc cagttaaacc gcgttcacct tgggctcctt tttcaccttt agctccttga
    74041 gctccagtta gaccgcgttc gcctcggtct cctttttcac ctttagctcc agttagaccg
    74101 cgttcgcctc ggtctccttt ttcaccttta gctccttgag ctccggttag accgcgttca
    74161 cctcggtctc ctttttcacc tttagctcct tgagctccag ttagaccgcg ttcacctcgg
    74221 tctccttttt cacctttagc tccttgagct ccagttagac cgcgttcgcc tcggtctcct
    74281 ttttcacctt tagctccagt tagaccgcgt tcaccttggt ctcctttttc acctttagct
    74341 ccatctttaa tagcaatttt ttgaacaagt tcgtctacac cttcagtata aacaccgttt
    74401 ccatcgttat caagatagaa agtgaggtta tttgtatcac cgactttatt ttgatcaaca
    74461 cgtggtttta ctgtatcgat tagatcttta gccacaccaa tttgcataat acgtggctta
    74521 gcttctttag taacactatt actaatcggc aatcctaaaa gtgtttcgtt accaaatcga
    74581 tgaactttat aggtaatttg acgttgtcct ttttcacctt ctcgaactaa tctagtttga
    74641 ccttctggta acttactagt tggaagatag acagtttgga agtcaatgtc ttctgaaaca
    74701 gtcttattat tagtaccacc ataagggttt gcatccaagt atagtgggtt tgctctataa
    74761 taatagttag agttactgta tgggtcattg ctagtagcgg caccaccacc accttggtcc
    74821 acgttaaaag taacaggttt caaacgaaca gacaaatcac catttagatt aatgataggc
    74881 aaactaaatc tgatagtttg ttccgtattt gttgaaatag cagaggtcat actgtatcct
    74941 gagtgagata cgtagttggc accctgacta atagattttg attgctccct tactcttgga
    75001 tttgaacttg tgatcgttgc atttgaagga tttccaaatc catccccttt atccaagata
    75061 aaattattat taacaaattc tctaagattt cctggcgcag aataattaat tgtaaattca
    75121 atattatcac ctctacgtac tgtcgttaca tcataatgga tttcacgacc accacgtgaa
    75181 tgtcctatac cacgaaatga atgtgagccc tgactgatgt cagaaaatgc aatagtatta
    75241 tttggattta agattggttt attttctggt ccagctgctc taaaaccact tccagccgct
    75301 ctaaagccac ttcctgctgt tctaaaacca ctataccctc tatcaacatc ttccttacgg
    75361 atagctggat tttggcgagc atcagaaagg ttcaaacctg gtttcaagat ttcattagta
    75421 gattttggag ctgaagttgt ttctactttg gcaggtgcat tagttgctaa aacgctacta
    75481 tcaacagctg aacggtcagt cgttcttgca gctggcttag cttcttcttt ggcttctgtt
    75541 gtgtcagctt tcttcgctac aggcgtttct gatacagttc ctttgttaga gttagaacga
    75601 agttctagac caataataga tgactctgct gctgataatt cagcttcaga tgcatctgct
    75661 ttcccaagca agctttgacc agcttggata cttgtttgca agttagcagc acttgcttct
    75721 gtatataact tgctttctaa ctttttagca cgcgaaagag ccgttaacaa ttttgacttg
    75781 tcaatagcat cttgatgcgt tacttcctct tttttgtctt ttgcttcttc aactttttct
    75841 gctggtttag taacttctcc agttttaact ggagtcgttt ctactggatt agctacagtt
    75901 ggagctgcat aggttttctc tttattagac gcagaaacct ctgctggttt agtagctgct
    75961 tctcccctac caacagaaat actattggta gtttcttgtt tgttttcttc cgcttgtact
    76021 gtttggacac tagctgctgc acctaatacc aaagcggtac cgagcaagac actaactgca
    76081 ccaaagtaat acttacgaat agaataacgt tgttgcatgc tataccagtc aaatgatttt
    76141 ttatgtgaat gtttcatttt aaactcctag atagtatttt
//
LOCUS       DAVLZS010000003        70557 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLZS010000003 DAVLZS010000000
VERSION     DAVLZS010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70557
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.003"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..1000
                     /locus_tag="VYO88_000153"
     CDS             <1..1000
                     /locus_tag="VYO88_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1718331.1"
                     /translation="LADDGKVKCINLSGKKLDQTALPMQVTQFDFEDKLFIKGLVLEE
                     EKTFAVDHDATVVEADGTEVRIAPLDVQYQNATIWGKLITNFAGPMNNFILGVVVFWV
                     LIFMQGGVRDVDTNQFHIMPQGALAKVGVPETAQITKIGSHEVSNWESLIQAVETETK
                     DKTAPTLDVTISEKGSDKQVTVTPEDSQGRYLLGVQPGVKSDFLSMFVGGFTTAADSA
                     LRILSALKNLIFQPDLNKLGGPVAIFKASSDAARNGIENILYFLAMISINIGIFNLIP
                     IPALDGGKIVLNILEAIRRKPLKQEIETYVTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            1013..2866
                     /locus_tag="VYO88_000154"
     CDS             1013..2866
                     /locus_tag="VYO88_000154"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1718332.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            2965..4344
                     /gene="bglA"
                     /locus_tag="VYO88_000155"
     CDS             2965..4344
                     /gene="bglA"
                     /locus_tag="VYO88_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1718333.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            4536..6344
                     /gene="glmS"
                     /locus_tag="VYO88_000156"
     CDS             4536..6344
                     /gene="glmS"
                     /locus_tag="VYO88_000156"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1718334.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEKYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKRALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMVIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(6421..6558)
                     /locus_tag="VYO88_000157"
     CDS             complement(6421..6558)
                     /locus_tag="VYO88_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718335.1"
                     /translation="MKIKEQTRKLATGCSKQCFEVVDRTDEISNHTYGKATLTWFEEI
                     F"
     gene            6615..7664
                     /locus_tag="VYO88_000158"
     CDS             6615..7664
                     /locus_tag="VYO88_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1718336.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLTAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(7764..11534)
                     /gene="spuA"
                     /locus_tag="VYO88_000159"
     CDS             complement(7764..11534)
                     /gene="spuA"
                     /locus_tag="VYO88_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1718337.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNYRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGDRGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDTASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVRNESV
                     ENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            11951..12364
                     /gene="rpsL"
                     /locus_tag="VYO88_000160"
     CDS             11951..12364
                     /gene="rpsL"
                     /locus_tag="VYO88_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1718338.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            12384..12854
                     /gene="rpsG"
                     /locus_tag="VYO88_000161"
     CDS             12384..12854
                     /gene="rpsG"
                     /locus_tag="VYO88_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1718339.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            13279..15360
                     /gene="fusA"
                     /locus_tag="VYO88_000162"
     CDS             13279..15360
                     /gene="fusA"
                     /locus_tag="VYO88_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1718340.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            15464..19855
                     /locus_tag="VYO88_000163"
     CDS             15464..19855
                     /locus_tag="VYO88_000163"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1718341.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEAIYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFINKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            19957..20220
                     /locus_tag="VYO88_000164"
     CDS             19957..20220
                     /locus_tag="VYO88_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV1718342.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            20213..20491
                     /locus_tag="VYO88_000165"
     CDS             20213..20491
                     /locus_tag="VYO88_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1718343.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWFLVYKVDKSELILNLLRTGSHSDLF"
     gene            20512..20664
                     /locus_tag="VYO88_000166"
     CDS             20512..20664
                     /locus_tag="VYO88_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718344.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            20686..21927
                     /locus_tag="VYO88_000167"
     CDS             20686..21927
                     /locus_tag="VYO88_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1718345.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLYAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVGGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            21937..22167
                     /locus_tag="VYO88_000168"
     CDS             21937..22167
                     /locus_tag="VYO88_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1718346.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            22390..23112
                     /locus_tag="VYO88_000169"
     CDS             22390..23112
                     /locus_tag="VYO88_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1718347.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEIFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            23329..24663
                     /gene="pepC"
                     /locus_tag="VYO88_000170"
     CDS             23329..24663
                     /gene="pepC"
                     /locus_tag="VYO88_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1718348.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(24719..25630)
                     /locus_tag="VYO88_000171"
     CDS             complement(24719..25630)
                     /locus_tag="VYO88_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1718349.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(25654..26457)
                     /locus_tag="VYO88_000172"
     CDS             complement(25654..26457)
                     /locus_tag="VYO88_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1718350.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(26485..27474)
                     /gene="manX"
                     /locus_tag="VYO88_000173"
     CDS             complement(26485..27474)
                     /gene="manX"
                     /locus_tag="VYO88_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1718351.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(27707..28726)
                     /gene="adhP"
                     /locus_tag="VYO88_000174"
     CDS             complement(27707..28726)
                     /gene="adhP"
                     /locus_tag="VYO88_000174"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1718352.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(29065..29877)
                     /locus_tag="VYO88_000175"
     CDS             complement(29065..29877)
                     /locus_tag="VYO88_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1718353.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            30067..31485
                     /locus_tag="VYO88_000176"
     CDS             30067..31485
                     /locus_tag="VYO88_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1718354.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLVITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            31538..32245
                     /locus_tag="VYO88_000177"
     CDS             31538..32245
                     /locus_tag="VYO88_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1718355.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGLVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            32340..33314
                     /gene="folP"
                     /locus_tag="VYO88_000178"
     CDS             32340..33314
                     /gene="folP"
                     /locus_tag="VYO88_000178"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1718356.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            33316..34638
                     /locus_tag="VYO88_000179"
     CDS             33316..34638
                     /locus_tag="VYO88_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1718357.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            34619..35173
                     /gene="folE"
                     /locus_tag="VYO88_000180"
     CDS             34619..35173
                     /gene="folE"
                     /locus_tag="VYO88_000180"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1718358.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHLLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            35216..36028
                     /gene="folB"
                     /locus_tag="VYO88_000181"
     CDS             35216..36028
                     /gene="folB"
                     /locus_tag="VYO88_000181"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEV1718359.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRNRGIHILKESSVLAT
                     EPWGGVEQDSFTNQVVEVETWLPAQVLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(36178..36495)
                     /locus_tag="VYO88_000182"
     CDS             complement(36178..36495)
                     /locus_tag="VYO88_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1718360.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            36852..37298
                     /gene="rplM"
                     /locus_tag="VYO88_000183"
     CDS             36852..37298
                     /gene="rplM"
                     /locus_tag="VYO88_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1718361.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            37318..37710
                     /gene="rpsI"
                     /locus_tag="VYO88_000184"
     CDS             37318..37710
                     /gene="rpsI"
                     /locus_tag="VYO88_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1718362.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRTG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            38020..38172
                     /locus_tag="VYO88_000185"
                     /pseudo
     CDS             38020..38172
                     /locus_tag="VYO88_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            38328..38666
                     /locus_tag="VYO88_000186"
     CDS             38328..38666
                     /locus_tag="VYO88_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV1718363.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDEHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            38882..40291
                     /locus_tag="VYO88_000187"
     CDS             38882..40291
                     /locus_tag="VYO88_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1718364.1"
                     /translation="MGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVAREITSGVLE
                     GKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEPNEEGLQFYD
                     NLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVVFKRYKDKVK
                     YWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVASARAVKIGHE
                     INPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYPEHIFKYWER
                     KGISVDFAAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETEDLVKNNYVK
                     ASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVTADGMVHDDYRIEYLDA
                     HIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDNGKGSYNRSP
                     KKSFGWYKEVISSNGESVE"
     gene            40343..40582
                     /locus_tag="VYO88_000188"
     CDS             40343..40582
                     /locus_tag="VYO88_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEV1718365.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            40712..41026
                     /locus_tag="VYO88_000189"
     CDS             40712..41026
                     /locus_tag="VYO88_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV1718366.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            41144..43123
                     /locus_tag="VYO88_000190"
     CDS             41144..43123
                     /locus_tag="VYO88_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1718367.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDATERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMVQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            43133..43447
                     /locus_tag="VYO88_000191"
     CDS             43133..43447
                     /locus_tag="VYO88_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV1718368.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            43478..43984
                     /locus_tag="VYO88_000192"
     CDS             43478..43984
                     /locus_tag="VYO88_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718369.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFISPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            44064..45410
                     /gene="celB"
                     /locus_tag="VYO88_000193"
     CDS             44064..45410
                     /gene="celB"
                     /locus_tag="VYO88_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV1718370.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            45791..45967
                     /locus_tag="VYO88_000194"
     CDS             45791..45967
                     /locus_tag="VYO88_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718371.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            46368..48581
                     /locus_tag="VYO88_000195"
     CDS             46368..48581
                     /locus_tag="VYO88_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV1718372.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHTTDIPARFGSGWTGYSWNRSLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAERLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(48803..49279)
                     /locus_tag="VYO88_000196"
     CDS             complement(48803..49279)
                     /locus_tag="VYO88_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1718373.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLISRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            49502..52705
                     /locus_tag="VYO88_000197"
     CDS             49502..52705
                     /locus_tag="VYO88_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1718374.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASIRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            53084..53469
                     /gene="tnpA"
                     /locus_tag="VYO88_000198"
                     /pseudo
     CDS             53084..53469
                     /gene="tnpA"
                     /locus_tag="VYO88_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(53848..54477)
                     /locus_tag="VYO88_000199"
     CDS             complement(53848..54477)
                     /locus_tag="VYO88_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1718375.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(54487..55488)
                     /locus_tag="VYO88_000200"
     CDS             complement(54487..55488)
                     /locus_tag="VYO88_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1718376.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISALEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKETYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(55519..56160)
                     /locus_tag="VYO88_000201"
     CDS             complement(55519..56160)
                     /locus_tag="VYO88_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1718377.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(56179..56994)
                     /locus_tag="VYO88_000202"
     CDS             complement(56179..56994)
                     /locus_tag="VYO88_000202"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1718378.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            57266..57700
                     /locus_tag="VYO88_000203"
     CDS             57266..57700
                     /locus_tag="VYO88_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1718379.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            57712..58902
                     /locus_tag="VYO88_000204"
     CDS             57712..58902
                     /locus_tag="VYO88_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV1718380.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            58913..59404
                     /locus_tag="VYO88_000205"
     CDS             58913..59404
                     /locus_tag="VYO88_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1718381.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVTIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            59419..60198
                     /locus_tag="VYO88_000206"
     CDS             59419..60198
                     /locus_tag="VYO88_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1718382.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            60185..61003
                     /locus_tag="VYO88_000207"
     CDS             60185..61003
                     /locus_tag="VYO88_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1718383.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            61003..61296
                     /locus_tag="VYO88_000208"
     CDS             61003..61296
                     /locus_tag="VYO88_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1718384.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            61318..63219
                     /locus_tag="VYO88_000209"
     CDS             61318..63219
                     /locus_tag="VYO88_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV1718385.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKGYI
                     QKCKFFLFDWIEQVREFRPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEEELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPILATYHFFSDKMDLEEAYHFASKELKQQ
                     IETQILEDGSQFEQSILYHVEVYKALLDLCILLPDLQDSFQELLEKMATYIQMMTGLD
                     GRTLTFGDSDSTETTEILSLSAMVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFRSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREVDERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            63279..64280
                     /locus_tag="VYO88_000210"
     CDS             63279..64280
                     /locus_tag="VYO88_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1718386.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(64390..64725)
                     /locus_tag="VYO88_000211"
     CDS             complement(64390..64725)
                     /locus_tag="VYO88_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718387.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLTYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(64736..64978)
                     /locus_tag="VYO88_000212"
     CDS             complement(64736..64978)
                     /locus_tag="VYO88_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718388.1"
                     /translation="MKKEKRQLHYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(64989..65531)
                     /locus_tag="VYO88_000213"
     CDS             complement(64989..65531)
                     /locus_tag="VYO88_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV1718389.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(65547..65741)
                     /locus_tag="VYO88_000214"
     CDS             complement(65547..65741)
                     /locus_tag="VYO88_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1718390.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            65907..66857
                     /gene="rsmH"
                     /locus_tag="VYO88_000215"
     CDS             65907..66857
                     /gene="rsmH"
                     /locus_tag="VYO88_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1718391.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            66869..67186
                     /gene="ftsL"
                     /locus_tag="VYO88_000216"
     CDS             66869..67186
                     /gene="ftsL"
                     /locus_tag="VYO88_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1718392.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            67190..69442
                     /gene="pbpX"
                     /locus_tag="VYO88_000217"
     CDS             67190..69442
                     /gene="pbpX"
                     /locus_tag="VYO88_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV1718393.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            69444..70424
                     /locus_tag="VYO88_000218"
     CDS             69444..70424
                     /locus_tag="VYO88_000218"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1718394.1"
                     /translation="MFISLSAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT        21101 a        12779 c        15772 g        20905 t
ORIGIN      
        1 acttgctgat gatggtaagg ttaaatgcat caatctctca ggtaaaaaat tggatcaaac
       61 agccctccct atgcaggtga cccagtttga ttttgaagac aagctcttta tcaaaggatt
      121 ggttctggaa gaagaaaaaa catttgcagt ggatcacgat gcaacggttg tggaagcaga
      181 tggtactgag gttcggattg cacctttaga tgttcaatat caaaatgcga ctatctgggg
      241 caaactgatt accaattttg caggtcctat gaacaatttt atcttaggtg tcgttgtttt
      301 ttgggtttta atctttatgc agggtggtgt cagagatgtt gataccaatc agttccatat
      361 catgccccaa ggtgccttgg ccaaggtagg agtaccagaa acggcacaaa ttaccaagat
      421 tggctcacat gaggttagca actgggaaag cttgatccaa gctgtggaaa cagaaaccaa
      481 agataagacg gcaccgactt tggatgtgac tatttctgaa aaggggagtg acaaacaagt
      541 cactgttaca cccgaagata gtcaaggtcg ttaccttcta ggtgttcaac cgggggttaa
      601 gtcagatttt ctatccatgt ttgtaggtgg ttttacaact gctgctgact cagctctccg
      661 aattctctca gctctgaaaa atctgatttt ccaaccggat ttgaacaagt tgggtggacc
      721 cgttgctatt tttaaggcaa gtagtgatgc tgctagaaat ggaattgaga atatcttgta
      781 cttcttggca atgatttcca tcaatattgg gatttttaat cttattccga ttccagcctt
      841 ggatggtggt aagattgtgc tcaatatcct agaagccatc cgccgcaaac cattgaaaca
      901 agaaattgaa acctatgtca ccttggccgg agtggtcatc atggttgtct tgatgattgc
      961 tgtgacttgg aatgacatta tgcgactctt ttttagataa tcgaggaata ttatgaaaca
     1021 aagtaaaatg cctatcccaa cgcttcgcga aatgccaagc gatgctcaag ttatcagcca
     1081 tgctcttatg ttgcgtgctg gttatgttcg ccaagtttca gcaggtgttt attcttatct
     1141 accacttgcc aaccgtgtga ttgaaaaagc taaaaacatc atgcgccaag aattcgaaaa
     1201 gattggtgct gttgagatgt tggctccagc ccttcttagt gcagaattgt ggcgtgaatc
     1261 aggtcgttac gaaacctatg gtgaagacct ttacaaacta aaaaaccgtg aaaaatcaga
     1321 ctttatctta ggtccaactc acgaagaaac ctttacagct attgtccgtg attctgttaa
     1381 atcttacaag caattgccac tcaaccttta tcaaattcag cccaagtatc gtgatgaaaa
     1441 acgcccacgt aatggacttc ttcgtacacg tgagtttatc atgaaggatg cttatagttt
     1501 ccacgctaac tatgatagtt tggatagtgt ttatgatgag tacaaagcag cctatgagcg
     1561 tattttcact cgtagtggtt tagacttcaa ggctattatt ggtgacggtg gagccatggg
     1621 tggtaaggat agccaagaat ttatggccat tacatctgct cgtacagacc ttgaccgctg
     1681 ggttgtcttg gacaagtcag ttgcctcatt tgacgaaatt cctgcagaag tgcaagaaga
     1741 aatcaaggca gaattgctca aatggatagt ctctggtgaa gataccattg cttactcaag
     1801 tgagtctagc tatgcagcta acttagaaat ggcaacaaac gagtacaaac caagcaaccg
     1861 tgttgtcgct gaagaagaag ttactcgtgt tgcaacgcca gatgttaaat caattgatga
     1921 agttgcagcc ttcctcaatg ttccagaaga acaaacgatt aaaaccctct tctacattgc
     1981 agatggtgag cttgttgcag cccttctagt tggaaatgac caactcaacg aagtcaagtt
     2041 gaaaaatcac ttgggagcag atttctttga cgttgctagc gaagaagaag tggcgaatgt
     2101 tgttcaagca ggatttggtt cacttggacc agttggtttg ccagagaata ttaaaattat
     2161 tgcagatcgt aaggtacaag atgttcgcaa tgcagttgtc ggtgctaacg aagatggcta
     2221 ccacttgact ggtgtgaacc caggccgtga ttttactgca gaatatgtgg atatccgtga
     2281 agttcgtgag ggtgaaattt ccccagatgg acaaggtgtc cttaactttg cgcgtggtat
     2341 tgagatcggt catattttca aactcggaac tcgctattca gcaagcatgg gagcagatgt
     2401 cttggatgaa aatggtcgtg ctgtgccaat catcatggga tgttacggta tcggtgtcag
     2461 ccgtcttctt tcagcagtga tggagcaaca cgctcgcctc tttgttaaca aaacgccaaa
     2521 aggtgaatac cgttacgctt ggggaatcaa tttccctaaa gaattggcac catttgatgt
     2581 gcatttgatt actgtcaatg tcaaggatga agaagcgcaa gccttgacag aaaaacttga
     2641 agcaagcttg atgggagctg gttatgaagt cttgacagat gaccgtaacg aacgtgtcgg
     2701 tgttaaattt agcgatagtg acttgattgg tcttccaatc cgtatcactg ttggtaaaaa
     2761 agcggccgat ggcattgtag aagttaagat caaggcaact ggtgacacca ttgaggttca
     2821 tgcagataac gtgcttgaaa cgcttgaaat cctaagcaag aaataaaaac tataatcaga
     2881 agaaaaacaa ggaaaaaatg taactagttt ttaccttgtt ttttctgtat aatgggagaa
     2941 atgagtagat aaagaggtaa atgtatgcta agatttccaa aggattttgt ctggggatcc
     3001 tctacttctg gaccgcaaac agaaggacgt gtagctggtg acggtaaggg agacaatctc
     3061 tgggattact ggttccaagt ggagccaaat cgttactata atgggattgg ttcagataag
     3121 acatcgactt tttatgaaaa ttgggagcgg gatattgagc ttttgttaga gactggtcac
     3181 acagcctttc ggacttctat tcagtggtca cggatttttc cacaaggctg tggaaaagtc
     3241 aaccctcaag gtgtggattt ttatcgtaag gtctttgagg ctattaaggc taaaggaatt
     3301 cgtctgttag tcaatctcta tcattttgat ttaccttttg cccttcaaga ggatggtgat
     3361 ggttgggaaa ataaggcgac agtctcagcc tatgaagact atgctcgttt ttgttttgag
     3421 acttatggag atttagtgga tcaatggatt acctttaacg agcccatcgt tcctgtagaa
     3481 tttggttatt tttatgatgc ccattatcca cataaggtgg atgcagaggc agctgttaag
     3541 gtagcctatc atacacaatt ggccagcagc cgggctgtta aggcttgcca tgaacttttg
     3601 cctgattcca agattgggat tgtcctcaac ttgacaccgg cttatccacg tagccagcat
     3661 cctgctgatg tcaaggcagc tcgtattgcg gccctttttc aggcccaatc tttcttagat
     3721 ccatctgtct tgggaactta tccacaggag ttagtagaaa tcttgcatga acacggtctt
     3781 ttacctgatg ctacagagga agagttggaa ctcattcgtg ataatacggt ggacttcctt
     3841 ggtgtgaact actatcaacc tttgcgtgtt atggctcctc gatttgctaa gcatccagag
     3901 agtccactct taccagaaca tttttacgag ccttatgtga tgcctggacg taaaatcaat
     3961 tctcaccgtg gttgggagat ttatgagcaa gggatttatg acatcgccca aaatatcaag
     4021 gaaaattatg gcaatattga gtggatgttg actgagaatg gtatgggtgt tgaaggggaa
     4081 gaaaaattcc gtcaagatgg aatgattcaa gatgattacc gtattgactt tgtaaaaggt
     4141 catcttcgtg aacttcaccg tgccattgaa gatggtgcca actgtaaggg ctacttgatt
     4201 tggaccttta ttgactgctg gtcatggctc aacagctata aaaatcgcta tggtttggtc
     4261 gaattagact tggaaacgca agaacgtcgt ctgaagaaat caggccactg gttcaaagaa
     4321 ttaagcgata ataatggatt ttaaaaagga ctctgactga ttatcccaat cggtcagagt
     4381 tttttgctta caggagctta atttgaacta taccaatttt tactcttgac aagtgaaaga
     4441 aacaagtata tactgttttt gctgattcta taaaagatga attagactat accaatttta
     4501 aggagaaagc acagcttgcc tgtgtcgtat atactatgtg tggaattgtt ggtgttgttg
     4561 gaaacacaaa tgcaactgat attttgattc aagggcttga aaagcttgaa taccgtggct
     4621 atgattctgc gggaattttt gtcctagatg gtgctgataa ccatttggtg aaggctgttg
     4681 gtcgtatcgc agaattgtct gccaagacag ctggtgttga gggaacaact ggtatcggac
     4741 atactcgttg ggcaactcat gggaaaccaa cggaagacaa tgctcaccca caccgatctg
     4801 agacagaacg ttttgtcttg gttcacaatg gggtaattga aaactacctt gaaattaaag
     4861 aaaaatacct tgctgggcac cacttcaaag ggcaaacaga tacggaaatc gccgtacatt
     4921 tgattggaaa atttgcggaa gaagacggtc tctcagttct tgaagccttt aaaagagctc
     4981 ttcatattat ccgtggttca tatgcctttg ccttgattga ctctgaaaat ccagatgtca
     5041 tctatgtagc gaaaaacaaa tctccacttt tgattggtct tggggaaggc tacaatatgg
     5101 tctgctcaga cgccatggct atgattcgtg aaactaacca atacatggaa atccatgacc
     5161 aagagttggt aatcgtcaag gctgatagtg tggaagttca agactatgat ggaaatcgtc
     5221 gtgagcgtgc tagctacact gctgaacttg acttgtcaga tatcggtaag ggaacttacc
     5281 cttactacat gctcaaggaa attgacgagc aaccaactgt tatgcggaaa ctcatccaag
     5341 cctacacaga tgaggctggt caagttgtcg tagacccaga tatcattaag gctgttcaag
     5401 acgcagaccg catctacatc cttgcagctg gaacatctta ccatgcagga tttgcttcta
     5461 agaaaatgtt ggaagaattg acagatacac cagttgaact tggaatctca tctgagtggg
     5521 gctacggtat gccacttctc agcaagaaac cactcttcat ttttatcagc caatctggtg
     5581 aaacagcgga tagtcgtcaa gttttggtca aggctaatga aatggtaatt ccaagcttaa
     5641 cagtgacaaa cgttccaggt tcaaccctct cacgtgaagc caactatacc atgctccttc
     5701 acgcaggtcc tgaaattgcc gtggcatcaa ctaaagccta tacagcgcaa atcgcagccc
     5761 ttgccttcct tgcaaaagca gtcggagaag caaatggtaa tgctaaagcg caagcctttg
     5821 acctggttca tgaattgtca atcgtagctc agtctatcga atcaactctt tcagagaaag
     5881 aaaccattga agccaaggtt cgtgaacttc ttgaaacaac tcgtaacgcc ttttacatcg
     5941 gacgtggtca agattactac gtagccatgg aagcaagtct caaactcaaa gagatttctt
     6001 atatccagtg tgaaggtttt gcggcaggag aactcaagca cggaaccatt gccttgattg
     6061 aagaaggaac gcctgttttg gctctcttgt cagatccagt tcttgccaac catactcgtg
     6121 gaaatatcca agaggtcgca gcccgtggtg ccaaagtcct cactatcgca gaagagaatg
     6181 tagccaaaga taccgacgat atcgtcctta cgaccgtaca tccatacctc tcaccaattt
     6241 caatggtcgt accaacgcaa ttagtcgctt actttgcaac cctccaccgt ggcctcgatg
     6301 tggataaacc acgtaacctt gctaaatcag taacggtaga ataagctaaa aaagtctagt
     6361 tatctaggct ttttctaatg agcaaattgg ttgcttgtac ttaagattcg tgttatactc
     6421 ttagaaaatc tcttcaaacc acgtcaacgt cgccttgccg taggtatggt tactgatttc
     6481 gtcagttcta tccacaacct caaaacactg ttttgagcaa cctgtggcta gcttcctagt
     6541 ttgctctttg attttcattg agtattagaa taatttttca aattgaagga cagagataga
     6601 caaggagaat cacaatggta gaattgggaa tttcaacatt tggggaaata acggagcttg
     6661 aagggactgg acaaacttac agtcatgctg aacgcattcg ccagttggtg gcagagattg
     6721 agctggctga caaggttggt ttggacgtat atgggattgg cgagcaccat cgggcggatt
     6781 ttgcagtatc agccccagag attgtcctga ccgctggggc agtcaatacc aagaaaatcc
     6841 gtttgaccag tgcagtcagc attctgtcaa gcatggaccc gattcgtttg ttccaacagt
     6901 atgccactat cgatgctttg tcaaatggac gagcggagat tatggctgga aggggctctt
     6961 tcacggaatc tttccctctg tttggttatg acttgaaaga ctacgactct ctttttgatg
     7021 agaaattaga cttgcttcag ttagtcaatg aaaagaccaa gttagactgg caaggtcgat
     7081 tgactcaaac gattgctggt aaagaagttt atcctcgtcc agttcaggac aaattgccct
     7141 tgtggatagc tacaggtggt catgtcgaat caacagtgaa gattgctcag gctggtctac
     7201 cgattgtata tgctattatt ggtggtaatc cacgttattt taaaaagttg attcaggctt
     7261 atcgtgagat tggaagcgaa gcgggccatg ctgacaaaga cttgaaagtg ggagcccatt
     7321 cttgggggtg gattgcggaa gatggtgagc aggcggtgaa agattatttc catccgacta
     7381 agcaagtggt ggatgctatt tccaaagacc gtccgcactg gcaggaattg cgttatgagc
     7441 aatatttgga gcaggtaggg ccaaatggcg ccatgtttgt tggcaatcca gatcaggtgg
     7501 ccgaaaaatt gattcgcatg atagaggatt taggattgga ccgcttcatg cttcatctac
     7561 cgcttggttc tatgcctcat gaccaggttc tgagagctat tgaactcttc ggaacacaag
     7621 ttgcacccaa agtacgagct tattttgcta tgaaagaggc ttaataaaaa atcctaatca
     7681 agtttattag gacaacaaat attgtacaaa aattaatccc ccgagctata atgcttgggg
     7741 gatttttcta taggagggct agtttagttc tcttttttat tttttagtaa gaaaccgaga
     7801 ccaaggagcg caaggaggct gattcctgca aataggagtt tgttttcgtt tttgattcct
     7861 gtatttggaa gttcagcttg tttatctggg gttgcaggta tattttcctt gctagagttt
     7921 tctaccgatt cgtttcgaac cgcttctttt acagatgatg cttgtgcttc ttgtgctggt
     7981 tgttcagctt gtgaatcagc tgtagcttgg ctaggtttat tttccgcatc agctactttg
     8041 gcatctggtt tagtagaatc aggtctagct tctggagctg ggtcttgatg ttcaggcttg
     8101 gaaggggttg agtctggttt ctcttctgca gttgactcat ggctagttcc attttgagag
     8161 actcgaagaa cagtagctgt aagggcattc aatttcaagc ctttttcagt ccattcaagt
     8221 cctttcgggt tggcaattcc gactgatcct gcttggtttt catctgccaa aacttccgca
     8281 tttcttagat gtgcaaaggc agttcccaaa ttaaattcgc gagctttttc atccgcattg
     8341 acaaagactg cgtagatatc gccgtttgga gcagtgattt ggtagccaat cactacatcc
     8401 tctttttcca caccattttg gcctgggaca gtgatgaggt ggacacggtc tttgatatct
     8461 tgaagactct taagtcggaa ggcatctgta gattgacgaa gggcaatcaa acctttcata
     8521 tagtcacggc tcttgacatt ttcaggataa gctttaccat ctgtagcctt agtccagtca
     8581 aacttgttga ctgcgtcgct agaatcgtaa gaatcatgga tgaagtaagg atagtcaaat
     8641 gggttgccgt ccttatcacg caacaagtga gatttgtttg gaaccttatc ctctgctact
     8701 ggagtcttgt aggctgggtc acggaattgt ttagtacgtc catattcctg accggagtgg
     8761 ataaatggag ttccttgagc tgtcaagacc atgagatttc caagtcgtaa acgacggtgg
     8821 atttcagcat agttctcagc cttgcttggg tcttttttga tagactgggc aatgatgtca
     8881 aagagggtca agttatcatg ggctgcgatg tattggatga catctccagg gctgtcagct
     8941 tcaaagttag ttggctgagc aatgagattt ttaaagatgg tgttgacatc acgcttgcca
     9001 cctgtgataa aggcaggttg accttcgttt ggataaccag atttgaggtt gttacggatg
     9061 tcatctgaaa agacagcgac agtatcggta tgtttcatcc aatcttggtc agcagcttta
     9121 gtaggcatgt tttcatcacc ggcataggtt ctccaacctt caccaagcat gatgaggttt
     9181 ggattgaggg cgcgtgcagc tttgtaagct tcttcgatag aagcggtgtc atggtctccc
     9241 atcatatcga aacggaatcc atccactttg taggtatcaa ctagatattt gatagagtca
     9301 actaggaggc gtttggtcat atggtgggtt gttcccaagc gtccaccacc aaagctagtt
     9361 cgaggtgtac catcggcatc cataaagtgg tagtagtttg gctctaggtc ttcaaagata
     9421 tcgactttgg ctgtgtggtt ataaacgaca tctaggatag ctcccatacc acgtttgtgg
     9481 atttcgttga tgaggttttt aaattctgcg attcgttttt ctggattctt aggatcgctt
     9541 gagtacatac cagtcaagga gaagtagttt tgagggtcat atccccagtt gtagttgctg
     9601 ttgcttgaag catagtcaga caagcgttca tggtttttca attcattgac aaagtagtaa
     9661 gacaagactg gaaggagctg gatatgggtt acacccaagt ctttgagata gtctagtttt
     9721 tcaatgaagg cttcaaaagt cccaaatggt ttggtcaagt cttttgcaat ggcaggatct
     9781 gaagtgaagt cacgcacatg agcttcgtag ataacggcgt cttcacgagt cttgaaattg
     9841 tgaatcttac cataagtcaa gtcttgaggt ccgagtttag ctggatctac aaaggcggct
     9901 ttagccactt tatgggcatc gtcaatcttg gcatcgtcgc tattccaagc agcaagagat
     9961 ttagcgtaag gatcgagtgc aagaacagtt ttaccttgac gctcgatttg gtattgataa
    10021 tagtagccag tgaaatctgt gattccgagt ttgtttgtgc tgtctagagt ttgtttccaa
    10081 gttcctctgt cccctttttc gagagcgaca gttccaacta ctttgtcagg gtcattcttg
    10141 tcgtagacaa caacagaaac cttatcagca cttggtgacc aaagggtcaa atcaacttgt
    10201 tttccttctt cttttaggtc agctcccagt ttgccatcat agctgtatgt ctcatctttc
    10261 aggcgccagc ttgttttggt agtgaattgg tcggaattgt agctaacagt ataaggatgt
    10321 tttgtgtcag agaaatctcc gctgtaggtc actttcttac cagcttcatc gattgcaaca
    10381 tcggtaatag ttaccttgtt tcctaggtga ttagtgatgt tggagtgttt gaggatatct
    10441 tcttttttag caccgacaag tgttgaaaag ctactttcaa tgctagaagt gcctacgtgt
    10501 tgggctcctg tcatacggat atcatggaca tagtatggat ttgtgtaaat cgattcatca
    10561 tcgtctttta ggaaaatttg gctatgattt ttcaaatctg tgaacttata attttcttta
    10621 cggattttca cgtcgtctcc ttgtttgctc tcatctagta ataaaaatcc aaattctctt
    10681 gcggcttcat taagaggaat gtcgatatag cggccatatt tgcctgtagc cgtaaagtct
    10741 gttccgtcag gccattgagc gctacttgga ttttttacat ctccccagta ccagagagat
    10801 ttcttgtcat agttgccatc tgtgcggtag tagttgacgc gaacagttcc tgcaggttgt
    10861 ggctcgtaag agaaaacctt gtaatcttgg tctaaccaag cctcgttcat ttttggaact
    10921 agtttttcta cagatttatc gccggttaga ttttttccag ctgtattgtt gatgaggaag
    10981 ctaattttct tggcttgttc tccctttaat ttgacatcta ggtaatagcc gtagtcatct
    11041 ttcttggcat ccttgaagga caaagctccg tttggccagt tttcagatgg tttttcaaca
    11101 tcgtcccaag tccatagtcc ttgagcatcc ttgttttctt caggaagttt tttgacatgg
    11161 atacggaagt agttatcttc gatgggctct tctgccttag tttcagttgt tactggacta
    11221 gtagaagtag ttggctctgt tgcaggtttt tcttctgttt tctctaggga agcgtttgca
    11281 tttctaggtg aagaaatatc actttcgttc ttaccagagc cagcagctgt atcagtaaga
    11341 ggttgggcaa gggtggttgt atttctgtag ttgggttcgt tagtggttgg tgtactttcg
    11401 tcggatgaga tagttggtgt agccatggca agcaagacaa ggcttgcgcc gataaggaca
    11461 gaaccagttc catttttgag ggaacggatg ctgtagacca tttttttctc agtgtgagat
    11521 ggtgtttttc tcataatgat tctccaatca ataaatttct atatcagtat agcatgtagt
    11581 aaaacaatat gcaagcgttt tcttttattt gtgaaaaaaa ttcttacttt tgagaagttt
    11641 tctgtactat tttatatgtc agtataaatg acggagataa aaatgtcaca taagccaagc
    11701 cgtattatta ggaagatgat gtgttcccag ctatttttat tcagaaattg atctctaaca
    11761 ttaccaataa aaaagaaaaa tatcttgaca agcaagggaa aattttgtta caataataga
    11821 cggtactttt tacttttggt ctctcaagag tgtacaggga cgtgctgaca aatgttgcaa
    11881 aagtacacac agatgatatc tgtcaccaag tgtatcatca ccaaaaataa aaaaacacag
    11941 gagaatgtag atgcctacaa ttaaccaatt ggttcgcaaa ccgcgtaaat caaaagtaga
    12001 aaaatctaaa tcaccagctt tgaacgttgg ttacaatagt cataaaaaag ttcaaacaaa
    12061 cgtttcttca ccacaaaaac gtggtgttgc aactcgtgtt ggaacaatga cacctaaaaa
    12121 acctaactca gcccttcgta aattcgctcg tgtacgtttg agcaacctta tcgaagttac
    12181 tgcctacatc ccaggtatcg gacacaactt gcaagagcac agcgtggtgc ttcttcgcgg
    12241 tggacgtgta aaagaccttc caggggtacg ttaccatatc gtccgtggtg cacttgatac
    12301 tgcaggtgtt aacgatcgta aacaaggccg ttctaaatac ggtactaaac gtccaaaagc
    12361 ataaggaaag gggataaaga gaaatgagtc gtaaaaatag agctccaaaa cgtgacgtat
    12421 tgccagatcc gctatacaat tcacaactag ttactcgtct tatcaaccgc gttatgcttg
    12481 atggtaaacg tggtactgct gcttcaatcg tttacggtgc ttttgagcaa atcaaagaag
    12541 ctactggcaa cgatgcactt gaagtatttg aaacagctat ggaaaacatc atgcctgtac
    12601 ttgaagtacg tgcacgtcgt gttggtggtt ctaactacca agtcccagtt gaagttcgtc
    12661 cagaacgtcg tacaacactt ggacttcgtt ggttggtaac aatcgctcgt cttcgtggtg
    12721 aacacacaat gcaagaccgt cttgcaaaag aaatcttgga tgctgctaac aacactggtg
    12781 cagctgttaa gaaacgtgaa gatactcacc gtatggctga agctaaccgt gcattcgcac
    12841 acttccgttg gtaagatagg atgcgaaagc gttaagaaag tcccagagaa aatagggaat
    12901 cgaagcaggt tgcggttgca accaatgaga ttcatctttt tctccagact tttagcttga
    12961 gctcaactaa atcatgatgc taggcacggt aaggatgcaa ggtgaaaata ggaaactgac
    13021 gcagtattca acgaatacaa ggagttttat ctttttcacg cagcatcccg ttccagctca
    13081 catcggctaa ctaactttag cccgggttca aattagctaa atcgattagt attagctata
    13141 actcagctta ccatctcgta agttgaaacc aacaatagca tgaaaacatt gagaacgggt
    13201 aggtcctgcc tatccgtttt tattaaaatc gtgttataat agaatagaaa tcaaaaataa
    13261 ataggagaaa caaacctcat ggcacgcgaa ttttcacttg aaaaaactcg taatatcggt
    13321 atcatggctc acgtcgatgc cggtaaaaca acaactactg agcgtattct ttactacact
    13381 ggtaaaatcc acaaaatcgg tgaaactcac gaaggtgcgt cacaaatgga ctggatggag
    13441 caagagcaag aacgtggtat cacgatcaca tctgctgcga caacagctca atggaacaac
    13501 caccgcgtaa acatcatcga cacaccagga cacgtggact tcacaatcga agtacaacgt
    13561 tctcttcgtg tattggatgg tgcggttacc gttcttgact cacaatcagg tgttgaacct
    13621 caaactgaaa cagtttggcg tcaagcaact gagtacggag ttccacgtat cgtatttgcc
    13681 aacaaaatgg acaaaatcgg tgctgacttc ctttactctg taagcacact tcacgatcgt
    13741 cttcaagcaa atgcacaccc aatccaattg ccaatcggtt ctgaagatga cttccgtggt
    13801 atcattgact tgatcaagat gaaagctgaa atctatacta acgaccttgg tacggatatc
    13861 cttgaagaag acatcccagc tgaatacctt gaccaagctc aagaataccg tgaaaaattg
    13921 attgaagcag ttgctgaaac tgacgaagaa ttgatgatga aatacctcga aggtgaagaa
    13981 atcactaacg aagaattgaa agctggtatc cgtaaagcga ctatcaacgt tgaattcttc
    14041 ccagtattgt gtggttcagc cttcaaaaac aaaggtgttc aattgatgct tgatgcggtt
    14101 atcgactacc ttccaagtcc acttgacatc ccagcaatca aaggtattaa cccagataca
    14161 gacgctgaag aaactcgtcc agcatctgac gaagagccat ttgcagctct tgccttcaag
    14221 atcatgactg acccattcgt aggtcgtttg acattcttcc gtgtttactc aggtgttctt
    14281 caatcaggtt catacgtatt gaatacttct aaaggtaaac gtgaacgtat cggacgtatc
    14341 cttcaaatgc acgctaacag ccgtcaagaa atcgacactg tttactcagg tgatatcgct
    14401 gctgccgttg gtttgaaaga tactacaact ggtgactcat tgacagatga aaaatctaaa
    14461 atcatccttg agtcaatcaa cgttccagaa ccagttatcc aattgatggt tgagccaaaa
    14521 tctaaagctg accaagacaa gatgggtatc gcccttcaaa aattggctga agaagatcca
    14581 acattccgcg ttgaaacaaa cgttgaaact ggtgaaacag ttatctcagg tatgggtgaa
    14641 cttcaccttg acgtccttgt tgatcgtatg cgtcgtgagt tcaaagttga agcgaacgta
    14701 ggtgcgcctc aagtatctta ccgtgaaaca ttccgcgctt ctactcaagc acgtggattc
    14761 ttcaaacgtc agtctggtgg taaaggtcaa ttcggtgatg tgtggattga atttactcca
    14821 aacgaagaag gtaaaggatt cgaattcgaa aacgcaatcg tcggtggtgt ggttcctcgt
    14881 gaatttatcc cagcggttga aaaaggtttg gtagaatcta tggctaacgg tgttcttgca
    14941 ggttacccaa tggttgacgt taaagctaag ctttatgatg gttcatatca cgatgtcgac
    15001 tcatctgaaa ctgccttcaa gattgcggct tcactttccc ttaaagaagc tgctaaatca
    15061 gcacaaccag ctatccttga accaatgatg cttgtaacaa tcactgttcc agaagaaaac
    15121 cttggtgatg ttatgggtca cgtaactgct cgtcgtggac gtgtagatgg tatggaagca
    15181 cacggtaaca gccaaatcgt tcgtgcttac gttccacttg ctgaaatgtt cggttacgca
    15241 acagttcttc gttctgcatc tcaaggacgt ggtacattca tgatggtatt tgaccactac
    15301 gaagatgtac ctaagtcagt acaagaagaa attattaaga aaaataaagg tgaagactaa
    15361 tccgtcctca ctctagaagg aagtcactta gtggcttcct tttgtcttta gaaaatacct
    15421 ctaaatatgg taaaatagta gaagaataat gtgaggaaaa tgaatgtcaa atagttttga
    15481 aattttgatg aatcaattgg ggatgcctgc tgaaatgaga caggctcctg ctttagcaca
    15541 ggccaatatt gagcgagttg tggttcataa aattagtaag gtatgggagt ttcatttcgt
    15601 attttctaat attttaccga ttgaaatctt tttagaatta aagaaaggtt tgagcgaaga
    15661 attttctaag acaggcaata aagctgtttt tgaaattaag gctcggtctc aagaattttc
    15721 aaatcagctc ttgcagtcct actataggga ggctttctct gaaggtccat gtgctagtca
    15781 aggttttaag tccctttatc aaaatttgca agttcgtgct gagggtaatc agctatttat
    15841 tgaaggatct gaagcgattg ataaggaaca ttttaagaag aatcatcttc ctaatttagc
    15901 caaacaactt gaaaagtttg gttttccaac ttttaactgt caagtcgaga agaatgatgt
    15961 cctgacccaa gagcaggaag aggcctttca tgctgaaaat gagcagattg ttcaagctgc
    16021 caatgaggaa gcgcttcgtg ctatggaaca actggagcag atggcacctc ctccagcgga
    16081 agagaaacca gtctttgatt ttcaagcgaa aaaagctgca gctaaaccca agctggataa
    16141 ggcggagatt actcctatga tcgaagtgac gacagaggaa aatcgtctgg tatttgaagg
    16201 ggttgttttt gatgtggagc aaaaagtgac tagaacaggt cgtgttttaa tcaactttaa
    16261 aatgacggac tatacttcaa gtttttctat gcaaaagtgg gttaaaaacg aggaagaggc
    16321 ccagaagttt gacctcatca agaagaattc ttggctccga gttcgaggga atgtggagat
    16381 gaataacttc acacgcgatt tgactatgaa cgtacaggat ctgcaggaag ttgttcacta
    16441 tgagcggaag gatttgatgc cagaaggtga gcgtcgggtt gagtttcatg ctcatactaa
    16501 catgtcgact atggatgctt tgccagaggt cgaagagatt gttgcaacag ctgctaagtg
    16561 gggacacaag gcggttgcta tcacagacca tgggaatgtc cagtcctttc cacatggcta
    16621 taaggcggct aagaaagcgg gaatccagct gatctatggg atggaagcca atatcgtgga
    16681 ggaccgtgtc cctatcgtct ataacgaagt ggagatggac ttatcagaag caatctacgt
    16741 ggtctttgac gtggaaacga cgggactttc agctatctat aatgacttga ttcaggttgc
    16801 ggcctctaag atgtacaagg ggaatgttat tgctgaattt gatgaattta tcaatcctgg
    16861 gcatcccttg tcagctttta ctacagagtt aactggaatt acagatgatc atgtcaaaaa
    16921 tgccaaacca ctagaacaag ttttgcaaga attccaagaa ttttgcaagg atacggtcct
    16981 agttgcccac aatgctacct ttgacgttgg ctttatgaat gctaattatg agcgtcatga
    17041 tcttccaaag attagtcagc cagttattga tacgctggag tttgctagaa acctctatcc
    17101 tgagtataaa cgccatggtt tggggccttt gaccaagcgt tttggtgtgg ccttggaaca
    17161 tcaccacatg gccaactacg atgcggaagc gactggtcgt ctgcttttca tctttatcaa
    17221 agaggtagca gaaaaacatg gtgtgaccga tttagctaga ctcaacattg atctaatcag
    17281 tccagattct tacaaaaaag ctcggatcaa gcatgcgacc atctatgtca agaatcaggt
    17341 aggtctaaaa aatatcttta agctggtttc cttgtctaat accaagtatt ttgaaggagt
    17401 gccacggatt ccgagaacgg ttctagatgc ccatcgagag ggcttgattt taggttcagc
    17461 ctgttcagag ggtgaagttt ttgacgtggt cgtttctcaa ggtgtggatg cggcggttga
    17521 ggtggccaag tattatgact ttatcgaggt catgccaccg gctatctatg cgcccttgat
    17581 tgctaaagag caggtcaagg atatggagga actccagacc attatcaaga gtttgataga
    17641 ggttggagac cgccttggca agcctgttct ggctacggga aatgttcact atatcgaacc
    17701 ggaagaagag atttatcgtg aaattatcgt ccgtagtttg ggacagggtg cgatgattaa
    17761 ccgaactatc ggtcatggtg aacatgccca accagcgcca cttccaaagg ctcattttcg
    17821 aacgactaat gagatgttgg atgaatttgc ctttttggga gaggaactgg ctcgtaaact
    17881 ggttattgaa aacactaatg ccttggcaga aatatttgaa cccgttgaag tcgttaaggg
    17941 tgacttgtat acgcctttca tcaacaaggc tgaagaaaca gttgctgagt tgacctataa
    18001 gaaagctttt gagatttatg gaaatccgct gccagatatt gttgatttgc ggattgaaaa
    18061 agaattaaca tccatactgg ggaatggatt tgctgtgatt tatctggcat cgcagatgct
    18121 ggtgcaacgt tctaatgaac ggggttattt ggttggttct cgtgggtctg tcggatctag
    18181 tttcgttgcg accatgattg ggattacgga ggtcaatcct ctctctcctc actatgtctg
    18241 tggtcagtgt cagtacagtg agtttatcac agatggttcg tacggttcag gatttgatat
    18301 gccccataag gactgtccaa actgtggtca caaactcagt aaaaacggac aggatattcc
    18361 gtttgagacc ttccttggtt ttgatgggga taaggttcct gatattgact tgaacttctc
    18421 gggagaagat cagcctagcg cccacttgga tgtgcgtgat atctttggtg aagaatatgc
    18481 cttccgtgcg ggaacggttg gtacggtagc tgccaagact gcctatggat ttgtcaaggg
    18541 ttacgagcga gattatggca agttttatcg tgatgcagaa gtagaacgcc tcgctcaagg
    18601 agcggcgggt gtcaagcgga caacaggcca acacccgggg ggaatcgttg ttattccgaa
    18661 ctacatggat gtctacgatt ttacgcctgt ccagtatcca gcagatgatg tcacggctga
    18721 atggcagacc actcacttta acttccacga tatcgatgag aacgtcctca aactcgatgt
    18781 actgggacat gatgatccga ccatgattcg aaaacttcag gatttgtctg gtattgaccc
    18841 taataaaatt cctatggatg acgaaggcgt gatggcactc ttttctggga ctgatgtgct
    18901 aggggtaaca cctgaacaaa ttggaacgcc tacgggtatg ttggggattc cagagtttgg
    18961 aacaaatttc gtacgtggaa tggtagacga aacccatccg acaacctttg cggaattgct
    19021 tcagctgtct ggtctgtccc acggtactga cgtttggttg gggaatgctc aggatctgat
    19081 taagcaagga atagcggacc tatcgactgt tatcggttgt cgggacgaca tcatggttta
    19141 cctcatgcat gcgggtctgg aacctaagat ggcctttacc attatggaac gggtacgtaa
    19201 gggtttgtgg ctaaagattt cagaagagga gagaaatggc tatatcgaag ccatgaaggc
    19261 taataaggtg ccagagtggt atatcgaatc ctgtgggaaa attaagtaca tgttccctaa
    19321 ggcccatgcg gcagcctacg ttatgatggc cttgcgtgta gcttacttca aggttcacca
    19381 tcctatttat tactactgtg cttacttctc cattcgtgct aaggcttttg atatcaagac
    19441 catgggtgcg ggcttggagg ccatcaagcg cagaatggaa gaaatctctg aaaaacggaa
    19501 gaacaatgaa gcctctaatg tggaaatcga tctctataca actcttgaga ttgtcaatga
    19561 gatgtgggaa cgaggtttca agtttggcaa attagatctc taccgtagtc aggcgacaga
    19621 gttcctcatc gacggggata cccttatccc accatttgta gcaatggatg gtctgggaga
    19681 gaacgttgcc aagcaactgg tgcgggcgcg tgaagaggga gaattcctct ctaaaacaga
    19741 actacgcaag cgtggtggac tctcatcaac cttggttgaa aagatggatg agatgggtat
    19801 tcttggaaat atgccagagg ataaccagtt gagtttgttt gatgagttgt tttaaaaaat
    19861 tgcttaataa tctattaaaa gaggctaacg tatatccaat agatttacat tagctttctt
    19921 ttttgttaaa atagtctatg gaaagagggt gagagtatgt caaagatgag tataagcatc
    19981 cgtctggata gtgaggttaa ggagcaggcc caacaggtgt ttagtaatct gggaatggat
    20041 atgacaacag ctattaatat tttccttcgt caggcaattc aatatcaggg attacctttt
    20101 gatgttagac tagacgaaaa tcggaagttg ctccaagtgt taacggattt agaccaaaat
    20161 cgtaatatga gccagtcttt tgaatcagtc tcagatttga tggaggactt acgtgcttaa
    20221 gattcgttat cataaacagt ttaaaaaaga ttttaagttg gctatgaagc gtggtttgaa
    20281 ggcagaatta ttagaagaag ttttgaattt tctggttcaa gaaaaagaac atcctgccag
    20341 atatcgtgat cattcattga cggcatccaa gcattttcaa ggagttcgtg aatgccatac
    20401 ccagccagat tggtttttgg tttataaagt agacaagtcg gaattgattt taaatttgct
    20461 gaggacaggc agtcacagtg atttatttta atctatttta agggggttct catgaaacta
    20521 agaatatttg cggaagataa gccggctaag aaggtatttg aatatcaatt agaacttgct
    20581 gatcgtacaa ttcttctatc gacagcactc ttgtcaggtg ctattgcttt agcaggaatc
    20641 ttttctgctt tgagagaaaa ataaaaatag aaaagagaaa acaggatggt tttaccaaat
    20701 tttaaagaaa atctagaaaa atatgcgaaa ttgttggttg caaatggaat caacgtgcaa
    20761 cctggtcaca ctttggctct ctctatcgat gtggagcaac gtgagttggc tcacttaatc
    20821 gtcaaagaag cttatgctct gggtgcgcat gaggttatcg ttcagtggac agatgatgtc
    20881 attaaccgtg agaaattcct ctatgcgcca atggagcgtt tggacaatgt gccagaatac
    20941 aagattgctg agatgaacta tcttttggag aacaaggcta gccgtcttgg ggttcgttca
    21001 tctgatccag gtgccttgaa cggagtggat gctgacaagc tttcagcttc tgctaaagct
    21061 atgggacttg ccatgaagcc tatgcgtatc gcaactcaat ctaacaaagt tagctggact
    21121 gtagcagctg cagcaggact tgagtgggct aagaaagtct tcccaaatgc tgcgagcgac
    21181 gaagaagcag ttgatttcct ttgggaccaa attttcaaaa cttgccgtgt ctacgaagca
    21241 gatcctgtta aggcttggga ggaacatgca gccattctca agagcaaggc cgatatgctt
    21301 aataaggagc aattttcagc ccttcactac acagcgccag gaacagattt aacacttggt
    21361 ttgccaaaga accacgtttg ggaatcagct ggtgctgtca atgcacaggg cgaagaattc
    21421 ttgccaaata tgccgacaga agaggtcttc acagcgcctg acttccgtcg tgcagatggt
    21481 tatgtcactt ctacaaaacc gcttagctac aacggaaata tcattgaagg cattaaggtg
    21541 acctttaagg atggacaaat cgtagatatc actgctgaga agggtgatca ggttatgaaa
    21601 gaccttgtct ttgaaaatgc gggtgcgcgt gccttgggtg aatgtgcctt ggtaccagat
    21661 ccaagtccaa tttctcagtc aggcattacc ttctttaaca cccttttcga tgaaaatgcg
    21721 tcaaaccact tggctatcgg tgcagcctat gcgactagcg tcgttggtgg agcagagatg
    21781 agtgaagaag agcttgaagc tgcagggctt aaccgttcag atgttcacgt agactttatg
    21841 attggttcta accaaatgga tatcgatggt attcgtgagg atggaacgcg agtacctctt
    21901 ttccgtaatg ggaattgggc aaattaagga gataatatgt taggaagtat gttcgttggt
    21961 ctcctagtgg gatttttagc aggtgctatg accaatcgtg gagagcgaat gggatgtttt
    22021 ggaaaaatgt ttctcggttg gatcggagcc tttctaggtc acttgctctt tggaacttgg
    22081 gggccagttt tatcaggaac agctattatc ccagctgttt taggtgccat gattgtctta
    22141 gctatttttt ggagacgagg aagttaattt cttaaatctg atactcaatg aaaatcaaag
    22201 agcaaactag gaaactagcc gcaggttgct caaagtactg ctttgaggtt gcagatagaa
    22261 ctgacgaagt cagtaacata tatacggcaa ggcgacgttg acgcggtttg aagagatttt
    22321 tgaagagtat gaaacgaaaa ggaggttggt cattgtacca gcctcctttt gatatgatat
    22381 aatagttcta tgagattaga taaattttta gttgcctgtg cggtgggaag tcggactgag
    22441 gtcaaaaact tgctcaaggc tgggcgcgtg actgtaaatg gtaaaaaaga aaaatcagct
    22501 aaattgcaga ttgatgaaaa aatagatgag attcgctttg atgggcaagt gttggagtat
    22561 gaagagtttg tctactacat gatgaacaag cccaaaggag ttatatcagc gactgaggat
    22621 cccaagcaca gaaccgttct ggacttgttg gatgacttgg cgcggagtaa ggaaattttc
    22681 ccagtaggac gcttggatat tgacacgcat ggtcttttgc tcttgaccaa tgatggtcag
    22741 ctggctcatg ttcttctttc gcccaagcgt catgtggaca agacttatct ggcacaagtc
    22801 aagggaatca tgacccaaga agatgtggag acatttgctg agggtattcc tctcaaagac
    22861 tttacctgtc aacccgctat actggagctt gtatccatag atacagaaaa gaatcaaagc
    22921 caaatccgtg tgaccattgc agaagggaag tttcatcaga tcaagcgtat ggtgggctac
    22981 tgtggcaagg aagtggtgga cttgcaacga ttgactatgg gaactttagt attagatgag
    23041 aacctagaac gaggggaatg gcgtcgcttg accaaggaag aattagaaat tctccgcgct
    23101 aatattattt aatttagttt aatactcaat gaaaatcaaa gagcaaacta ggaaactagc
    23161 cgcaggctgt acttgagtac ggcaaggcga cgttgacgtg gtttgaagag attttcgaag
    23221 agtataaatt cgaaaaaggt gagggacaat gtcctcgcct tttatgtttt ttagttgctt
    23281 cctttgtgaa aagagttata atagactgta gaataaaagg aggaatctat gaacgcgatt
    23341 caagaatcat ttactgataa actatttgcc aactatgaag caaatgtaaa ataccaagcg
    23401 attgaaaatg ctgccagcca caacggaatt tttgcagctc tggaacgtcg ccaaagccat
    23461 gtagacaaca cacctgtttt ctcattggat ttaaccaagg acaaggtcac taaccagaaa
    23521 gcgtctggtc gttgctggat gtttgcggct ctcaacacct tccgccacaa actcatctcg
    23581 caatacaaat tggagaactt tgagttgtca caagcccaca ctttcttctg ggataagtat
    23641 gagaaatcaa actggttctt ggagcaagtc attgcgactt cagaccaaga attgactagc
    23701 cgcaaggtta gcttcttact ccaaacacct caacaagatg gcggtcaatg ggatatggtc
    23761 gtttccctct ttgaaaaata cggtgtcgtg cctaagtcag tttatcctga gtctgtttca
    23821 tctagcagca gtcgtgagct aaatgcgatc cttaataaat tgcttcgtca agatgctcaa
    23881 atcttgcgtg acttgcttgt ttctggtgca gatcaagcga ctgttcaagc taagaaagaa
    23941 gacctcttgc aagaaatctt taactttctt gctatgtcat tgggacttcc accacgcaag
    24001 tttgactttg cttatcgcga taaagataac aactacaaaa gtgaaaaagg aatcacacca
    24061 caagagtttt acaagaaata tgtcaatctt cctttagaag actacgtttc tgttatcaat
    24121 gctccaactg ctgataaacc ttacggaaaa tcttacacag ttgagatgtt ggggaatgtt
    24181 gttggtagcc gtgcagttcg ctacatcaac gttccaatgg agcgcttgaa agaattggcg
    24241 attgcccaaa tgcaagcagg tgagactgtt tggtttggtt ctgatgtcgg ccagctcagc
    24301 aaccgtaagg ctggaatcct tgcgacagat gtttatgact ttgaatcaag catggacatt
    24361 aaacttactc aagacaaggc tggacgtttg gactatagcg aaagcttgat gacccacgcc
    24421 atggtcttga caggtgttga cttggacgaa aatggtaaat caaccaagtg gaaggttgaa
    24481 aactcatggg gagacaaggt cggtacagat ggttactttg ttgcctcaga cgcttggatg
    24541 gacgaataca cataccaaat cgttgttcgt aaggaattgc tgacagcaga agaacaagct
    24601 gcctatggag cagaaccaat cgtacttgca ccatgggatc caatgggagc cttggctgaa
    24661 taaaagcata gaaaaaagga atcagatttt agaacctggt tcctttttag ttgcttgatt
    24721 acatgatgtg aagaacatgt gccacaatac ccactgcgaa gagggcaagg ataatagtga
    24781 ttggagatac ttttttctta agtaagtaca tgcaaagtaa agtaaggagt agtcctgata
    24841 atccaggaat caacatatcc aagttttgtt ggaaagtagt aactttttca ggagtttgag
    24901 acaatccttg tcctacttgt gcgaatgctt cttggatacc tttagaccct tctggcaatt
    24961 tatcccaatg gatataagcc ttttcatcta gttgaacttt agaaacatcg aaagcaaatt
    25021 taatatttac ccaacgttga acaaggacag caagaatgaa catcccaagg atagaagctc
    25081 ctttagtgat atcttgaagg ataccaccag acatatcttt agtgatttct gatccagcct
    25141 tgtatccaat ctcttgaaca taccacaaga atgacatacg aatcaagttc catgcaacaa
    25201 agaagaggag tggacccaag atattgccag taagggcaag tgaagcaccg agagatccaa
    25261 ggattgggcg tactgtaaac cagaatactg ggtcaccgat accagcaaga ggtcccatca
    25321 taccgatttt gaccccttgg atagcagcgt catcgatttc cacaccgtta gcacgttctt
    25381 cttcaagcgc aagagtaacc cccatgactg gagcagctac gtatggatga gtgttgaaga
    25441 actcaaggtg acgctcaaga gcagcgattt gatcttcttt tttagtatag agttttttga
    25501 tagctggaat gagtgtataa gcccagccca agttttgcat ccgttcaaag ttccaagacc
    25561 cttgtaagaa ggttgaacgc caccaaactt ttttacgatc tgatttagtt aattgaagtt
    25621 tttcagtcat gatgttttca gtcctttctt atcttagtag tcttctagga tatcgccgat
    25681 tgggtcgtta gaagttgcgg ctcctccgcc accatttcca ccagttttag aaaggtgaag
    25741 gtagataaga gcgatagcaa caccgatagc accgaatccg attagagtaa tatctgacac
    25801 agcagcgaga acgaaaccaa gagcgaagaa tggccatact tcacgagttg ccatcatgtt
    25861 gataaccatg gcgtaaccaa cggcaacgac cataccacca ccgatagcca taccatcttt
    25921 gagccagtct ggcatggcac taaggatact ttgtacagtt tcagttggta ccataaggag
    25981 aagagctgca ggaagcgcga tacgaagtcc ttggaaaagt agcgcaatga aatgagcacg
    26041 ctccacagcg ccgaagtcac cttttttagc ggcagcatca gcagtgtgaa ccaatccaac
    26101 tgaaattgta cgaacaatca tagttaagaa tagaccagct acggcaagag ggatagcaac
    26161 cgcttgggca acaccgatac cagtcttggt aaagtcacca ccaagaacca tgataatggc
    26221 agcagcgaca gaagcaagtg cagcatcagg agcgatagca gcaccgatat ttgaccaacc
    26281 aagggcaatc atttgaagcg atccaccgag gataatccct gcttccaagt gacctgttac
    26341 aagcccaata agggtacagg ctacaagtgg ttggtgaaat tggaactggt cgaggatgcc
    26401 ttcaagacct gcaaagaagg ctacaacgac tactaaaacc atagaaataa tagacatgtt
    26461 taaaatcctt tcataaataa tggcttattt gacattggct ttgttaatca agtcaaacaa
    26521 atctttttta gaatcatttg gtactttacg gacatcaaat tcaacaccca agtcacgcat
    26581 tttttcaaat gtagcaacat cttctttgtc catagacaaa acggtattga ccaatgtttt
    26641 acctgttgag tgagccatag aaccaacgtt aagagtcttg attggcacgc cgccttcgat
    26701 ggcacgaagg gcatcttgag gtgtttcaaa caagataagg gcatgtgttt ctccaaaacg
    26761 tgggtctttt gaaatctcaa tcagtttttg aattggaacc acgttagcct tgacattacc
    26821 tggagctgct tgtttaatca attctttacg aaggtcgtct ttagccacat tatctgaagc
    26881 aacgatgata cgatttgctt ttgaatctgg agtccaagca gttgcaacct gaccgtgaag
    26941 tagacgtgtg tcaagacggg caagattgat tttcaattta ccgtctccga taacagttcc
    27001 ttctgggata gcagtttggg caactggagc agctgcagcg cttgcaactt cttcaactgg
    27061 atttagctct tctggaagag ctttgatgcc atctttggct tctttaatga tattagcagc
    27121 gactttttct acacctgcag cagcgtccat gaggcgctct gtgtaggctt gaatcaacat
    27181 cggtaagtta agtcctgtga tgatggcaaa cttacgctca ggattttctc ccatcacgcg
    27241 actagcttgg ttaaatggag aaccactcca aaggtcagcc aaaactagaa cctcatcttc
    27301 tgcgtcaaat gcagcaacag cgttattaaa cttagcgtat agatcatcag gaccttcatt
    27361 tggcataaag gtcacaactt gaaccttttc ttgttcacca aagatcatag atcctgactg
    27421 atgaataccc gcagcaaatt cgccgtggct cgcaataatg attccgatac tcattattgt
    27481 cattcctcct tttttgtttt agttttcatt taagaaaact ttaagactgt ttaagtataa
    27541 accgttttca taaaaaaagc aactatttat cataaaaaat taaaaaattt ttatttttgt
    27601 atgttgatat gttgagtttt tgaggagtaa tcttgaattc ttatttaaaa tttaatataa
    27661 aaaagttgga agaagcttcc aacttttaaa ataggtttct attagattag tgggtgaagt
    27721 cgagtaccat acgtccttgg atttggcctt tttccatttc gtcgaaaatg gcaacagcat
    27781 cttctactgg acgtttttga acaactggga ctaccagacc ttctgcacca aattggaagg
    27841 cttcttctaa gtctttacga gttccgacaa gagaaccgat gacttggatt ccatcgagga
    27901 ctgttttaac gatgctgagt tccatcattt cagaaggaag accaacagcg acgacgcgac
    27961 caccagcacg aatggagtca acagcctggt tgaaggcaac tttagacaca gcagttacga
    28021 cagctgaatg agctcctcca tcagtttttt ctttaatgag tccagctaca tcttcaactt
    28081 cgaggccgtt aatcacaatg tcagcgccta cttcttttgc aagggcaagt ttgtcattgt
    28141 tgatatcgac tgcgataaca tgagcattga atactttttt agcgtattga acagcgaggt
    28201 taccaagtcc accagcaccg taaagaacaa cccattggcc tggttcaact tttgcttctt
    28261 tgatagcttt ataggttgtt actccagcac atgtgataga agaagcttgg gctggatcaa
    28321 gtccgtcagg aactttgaca gcatagtcag cagttacgat acattgttca gccataccac
    28381 cgtctactga gtagccagca tttttcactg tacggcaaag ggtttcgcga ccagttgtac
    28441 agtattcgca agtgccacat ccttcaaaga accaagcaac gctgacgcgg tcaccgactt
    28501 taaggctttt cacatctgga gcaatctctt taacgatacc gataccttcg tgcccaagaa
    28561 cacgtcctgg gacttgacca aagtcaccat gagcaacgtg gaggtcggtg tggcaaacgc
    28621 cacagtattc aacttctaca agtgcttccc cagtttcaag tggacggagt actttttctt
    28681 caatagcaac accagtgctt tctggattta caacaacagc tttcatagct atcctccttg
    28741 atattgaccg agaacaggga caacgggact ggattgattt tttgtcaaca gagtcgagtg
    28801 tgacgagctc tcttgtattt atatgtgaag tatatcacaa aagaaagcct tttccaaggt
    28861 tttggagaca aaaagtagaa caatcgatta actggttgat gagactgtga aaagagcaca
    28921 aagaccagct tgcaagctgg tcatactctt cgaaaatctc ttcaaaccac gtcagcttca
    28981 tctacaacct caaagcagtg ctttgagcaa cctacggcta gcttcctagt ttgctctttg
    29041 attctcattg agtatcagta taggttataa gaataagtct tgtagggttt tggcaacccc
    29101 atcttggtcg ttggtaaggg aaatttgctc atctgcataa gggagtagct ctggattggc
    29161 atttttcatg gcataaccct tcccagcaaa agcgagcatt tcggtatcat tgtgttcatc
    29221 tccaaaggca atcaaatctt ttttgtcacg attcattatc ttgagcaagt agtccaaagc
    29281 aaaggccttg ttgacacctt ttggggtaca ttcaaggata ttgagcggac ctccccaggt
    29341 attgatagaa agttgatgct ggtagaaggc gttcatttct tttgccaagg catatttgtc
    29401 actggctctg gtctgcaaga ggatacagtt agggtccttg gtcaccaatt caggctggaa
    29461 ttgatcttca ggctggaaag cttctacacc aaatagtttg ggattggcaa tttcttcatt
    29521 gggatttgta atgtagaatt ttttacgata ttctccagcg ataaaatcgg cttgaatgtc
    29581 ctctgaacgt tgaaccatat ctagcagata ttttttgtct acagtcaaac acttttcaaa
    29641 atcccaaact tggtctggta aatgagtaag ggatccgttg aagttaatca taggagtgtc
    29701 taagcccagt tcacggtaaa aatcttttga catacggtaa gggcgacctg tcgtaataat
    29761 aacctgatgg cctttttcag caactttttt gatggttttt ttggtaaagt cagaaatttg
    29821 actgtctgag ttgagcaggg ttccatctag gtcaactgca ataatttttt tcgtcatatg
    29881 gacctttcta gtgtgttttc agataagatg tcttctatta taacagaaag caggcagaaa
    29941 agcagattcc aaacaaaaaa tgaaattgga ttaatttctt aaacaaatca aacaaagaca
    30001 ttgaaaaagt gaatgataaa tgatataatt ctattattgt tcgtaaaaat taaaaggaga
    30061 ttgatgatgg acaaattatt taaactaaaa gagaacggta cagacgttcg tacagaggtt
    30121 ctcgctggtt taacaacttt ctttgcaatg agctatattc tctttgtaaa cccacaaatt
    30181 ctttcgcaaa caggaatgcc tgctcagggt gtgtttcttg caacgattat cggtgcagtt
    30241 gctggtacct tgatgatggc cttctatgct aacttgccat acgctcaagc accaggtatg
    30301 ggactcaatg ccttctttac ctttacagtc gtatttggac ttggttattc atggcaagaa
    30361 gccctagcta tggtcttcat ctgtgggatt atttcattgg ttattacctt gacaaatgtt
    30421 cgtaaaatga tcattgaatc gattccaaat gcccttcgct cggctatttc agctggtatc
    30481 ggtgtcttcc ttgcctatgt agggattaag aatgctggac ttttgaaatt tacgattgat
    30541 ccaggcaact atactgttgt aggagaaggg gctgacaaag ctcaagcaac gattgcagca
    30601 aactcttcag cagttccagg attggtcagc tttaataatc cagctgtttt agtggctctt
    30661 gcaggacttg ccattactat cttctttgtc atcaaaggga ttaaaggggg aattattctc
    30721 tctatcttga caacaactgt tcttgctatt gcagttggtt tggttgattt gtctagtatc
    30781 gattttgcta ataaccatgt tggtgcagct tttgaagatt tgaagacaat ctttggtgca
    30841 gctcttggtt cagaaggatt gggagctttg gtttcagata cagctcgctt gcctgaaact
    30901 ctgatggcca ttcttgcctt ctcattgaca gatatttttg acacaattgg taccttgatc
    30961 ggtacaggtg aaaaagttgg tattgtagcg acaaatggtg aaaatcacca atcagccaaa
    31021 ttggataagg ctctttactc tgatttgatt ggaacgacag tcggtgccat tgcaggtact
    31081 tcaaacgtaa cgacttatgt tgagtctgct gctggtatcg gtgcaggtgg acgtactggt
    31141 ttgacagcct tggttgtagc tatctgtttt gcgatttcaa gcttctttag cccacttcta
    31201 gcgatcgtac caacagcggc tacagctcca atcttgatta tcgttgggat tatgatgctt
    31261 ggtagcttga aaaatatcca ttgggatgat atgtctgaag cagttcctgc cttcttcaca
    31321 tctatcttta tgggattcag ctactctatc actcaaggga ttgcagttgg tttcttgact
    31381 tacactttga ctaagcttgt caaaggtcaa gttaaagatg ttcatgccat gatttggatt
    31441 ttggatgcct tgtttatcct taactacatc agcatggcct tataatagaa tgacccaggg
    31501 ggatttcccc ccttttttaa tacaaaggag ataggtgatg aaagagaaaa atatgtggaa
    31561 agaattgttg aatcgtgcag gctggatttt ggtcttttta cttgccgtcc ttttatatca
    31621 ggttccccta gtggttacct ctattttgac tttaaaagaa gtagccctgc tacagtcagg
    31681 gctgatagtt gctggccttt caattgtggt tctggtgtta tttattattg gagctcgtaa
    31741 aacgcaattg gcaagtttta atttttcttt ttttagaact aaggatttgg cacgtttggg
    31801 cttgagttat ttagtcatta tctgttcaaa tatacttggt tctatcttgt tgcaactgtc
    31861 aaatgagacg acaacagcta accagtctca gattaacgat atggttcaga atagttctct
    31921 gatttctagc ttcttcttgc tagccttgct tgctccaatt tgtgaggaaa tcttgtgccg
    31981 tgggcttgtt cctaaaaaga ttttccgagg caaggagaac ttgggatttg tagtcggtac
    32041 gattgtgttt gctttattgc atcaaccaag taatttacct tctttattga tttatggagg
    32101 tatgtcgaca gttctatctt ggacggccta caagacccaa cgtttggaaa tgtcgatctt
    32161 gcttcacatg attgttaatg ggattgcttt ctgtttgttg gctcttgtgg tgattatgag
    32221 tcggacatta ggaatttctg tgtaaaagtt tttatgtagg aaccgacctc tttctactag
    32281 ggaaagatga atgcaatcgt gtccatcttt ttctttttat ggtaaaatag aaaaataata
    32341 tgatgaaaat ccttgaggga gtgaccgata tgtcaagtaa agccaatcat gcaaagacag
    32401 ttatttgcgg aattatcaat gtaaccccag actccttttc ggacggtggt caattttttg
    32461 ctcttgagca ggcactccag caggctcgta aattgatagc agaaggagcc agtatgctcg
    32521 atatcggcgg agaatcgact cggccgggaa gtagctatgt tgagatagaa gaggaaatcc
    32581 agcgtgttgt tccagtgatc aaagcgattc gcaaggaaag tgatgtcctc atctctattg
    32641 atacttggaa gagtcaagta gcagaggctg ctttggctgc tggtgccgat ctagtcaatg
    32701 atatcactgg tcttatgggt gatgagaaaa tggctcatgt ggtagctgaa gcgagagcgc
    32761 aagtggtcat catgtttaat ccagttatgg cgcgacctca gcaccctagc tcgctcatct
    32821 tccctcattt tggttttggt caagctttta cagaggaaga gttagcggac tttgaaacat
    32881 tgccaatcga agaattgatg gaggctttct ttgaacgagc actagcgaga gcggcagaag
    32941 ctggtattgc accagaaaat atcctgttgg atccaggaat tggctttggt ctgaccaaga
    33001 aagaaaatct gcttctttta cgggacctgg ataaactaca tcagaagggc tatccaatct
    33061 ttctcggagt gtcgcgcaag cgatttgtca tcaatatcct agaggagaat ggttttgaag
    33121 tcaatcctga gacagagctt ggtttccgca atcgggacac ggcttcggct catgtaacca
    33181 gtatcgctgc aagacagggt gtagaagtgg tgcgcgtgca tgacgtagct agtcacagga
    33241 tggcagttga aattgcctct gccattcgtc tggctgatga agcggaaaat ttagatttaa
    33301 aacaatataa ataagatgaa agaaattgaa aacaatcagt ggattgctaa ctaccggacg
    33361 gatcaaccgc attttggctt ggaacgaatg gtggaactgt tagctttgcg tggcaatccc
    33421 catctcaaac tcaaggttct ccatatcgga gggactaacg gcaagggctc gactattgct
    33481 tttttgaaaa agatgctaga aaagctaggg ctgagagttg gcgtgtttag ttcgccctat
    33541 ctcattcatt acacagacca gattagcatc aatggggaat cgatctcaga agcgaggcta
    33601 gaagctctca tggcagacta tcagtctttg ctggagggag aagcggtcgc caatttacag
    33661 ggcacaaccg agtttgagat tatcacagcc ctagcctatg actactttgc ctcagagcaa
    33721 gtagatgtgg ctatcatgga agttggcatg ggtggacttt tggatagtac caatgtctgt
    33781 cagcccattt tgacaggaat tacaactatt ggcttggatc atgtggccct acttggtgac
    33841 accttggagg ccatagcaga gcagaaggca ggtattatca aacaagggat gcccttggta
    33901 acagggcgta ttgctccaga agccttgact gtgattgacc gcattgcgga agggaaagat
    33961 gcgccgagac ttgcctacgg gacagattat caggttcgtc atcaagaaag tgtggtgaca
    34021 ggggaagtct ttgactatac aagtgctgtc agacaaggtc gcttccagac tagcctgctt
    34081 ggtttgtacc aaatagagaa tgctgggatg gccatagctt tacttgatac tttttgtcaa
    34141 gaagatggtc gagagctagc aagcaatgac tttcttggtc aagccttgga agaaacaagt
    34201 tggccagggc gtttggaaat cgtgtcaaga gatcccttga tgattttgga tggagcccac
    34261 aatccccatg ctatcaaggc cttgttggta accttgcaag aacgttttgc ggattatcat
    34321 aaggaaatcc tcttcacttg tatcaaaacc aaggccttgg aggatatgtt ggacttgctg
    34381 ggagccatgc cagataccga gcttactcta acacattttg cggatagtcg ggcgacggat
    34441 gaaagcgtgc tgaaagaggc agctaagtct agaaatctca gctaccaaga ttggcatgat
    34501 tttctagagc agaatttgac agataaaaaa gaagagaaac aaacagttag gattgtcaca
    34561 ggttccttgt atttcttgag ccaagtgagg gcctatctga tggagaggaa gaacgagaat
    34621 ggatacacaa aagattgaag cagctgtaaa aatgattatc gaggctgtag gagaggacgc
    34681 taatcgcgag ggcttgcagg aaacacctgc tcgtgtagcc cgtatgtatc aagagatttt
    34741 ttcaggtctt ggtcaaacag cagaggaaca tttgtcaaaa tcctttgaaa ttattgacga
    34801 taatatggtg gtagaaaagg atatcttttt ccataccatg tgtgaacacc acttattgcc
    34861 attttatggt agagcgcaca ttgcctacat tccagatggt cgtgtggcag gcttgtctaa
    34921 gctagcccgt acggttgaag tttattcgaa aaaaccacaa attcaagaac gtttgaatat
    34981 cgaagtggcc gatgccttga tggactatct aggtgctaaa ggagcctttg ttgtcattga
    35041 ggcggaacat atgtgtatga gtatgcgtgg tgttagaaaa ccaggcactg caaccttgac
    35101 gacagtagct cgtggtctat ttgaaacaga taaggacctc cgcgaccaag cttatcgttt
    35161 aatggggcta taaaaagaat ccgtttcaag cggatttttc tagaaaggaa tcattatgga
    35221 tcaactgcag attaaggatt tggaaatgtt tgcctatcat ggtctttttc ctagtgagaa
    35281 agaattgggg cagaaatttg tcgtttcagc catcctatcc tatgatatga ccaaggcagc
    35341 tacagacttg gatttaacag cctctgtcca ttacggagaa ttgtgtcagc agtggacgac
    35401 ttggtttcag gaaacgagtg aagatttgat tgaaacggta gcctataaac tggtggaacg
    35461 tacctttgag tcttatcctc ttgtccaaga aatgaagttg gaactgaaaa aaccttgggc
    35521 accggtgcat ttgtcactag atacttgctc ggtaaccatc catcgccgca agcaacgagc
    35581 ctttatcgcc ctaggaagca atatgggaga taaacaagca aacttgaaac aagccattga
    35641 gaaaatgcga aatcgaggta tccatattct caaagagtcc agtgtcttag cgacggagcc
    35701 ttggggtggt gttgagcagg atagctttac caatcaagtg gttgaagtag aaacatggtt
    35761 gcctgcccaa gtgctattag aaaccttgtt agccattgag tcagagctgg gacgggtgag
    35821 agaagtgcat tggggccctc gtttgattga tttggacttg ctctttgtgg aggaccagat
    35881 cctttataca gacgacctca tattgcctca tccttacata gcggaacgcc tttttgtcct
    35941 tgagtcctta caggaaattg cgcctcattt tatccatccg atattaaaac aaccgatccg
    36001 caacttgtat gatgctttga aaaaatagaa aaactctagt tttcagtcac ttgcaactga
    36061 aggctagagt ttttatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg
    36121 tactcaagta cagcttgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta
    36181 aaataggtca ttttcttctg ggaggaggat agtttctcta ccgtccatgt ctaaaaccag
    36241 tactcttggg ggataacgag ggtcgaaagg atggttaaag tcaaaatcaa tggctgtagg
    36301 gaggtgttga cttgaaaagt ggaaggtaat ctttccttgg ttattaagca attgaaactc
    36361 gagttcttct tccaattcaa agacattttt taagaaatgg tcgataatat accaaaaaga
    36421 gtcaatgatg tcatcaggca agctggtaac aatgccaaaa ctagcagacc gcatgtgggt
    36481 attggtaaaa gccatatctc tgtctccttt ctttttcctt atcatacagc aaataggatt
    36541 aaaaatcaag aaaaggtgat tttttgaaaa ggattttaac tacaaggaaa aagaagggaa
    36601 aaaattccca aaaatctacc gaagttaata ggtaaattcc caaattaact tgattatata
    36661 actttcagtt actttgagaa gttaccgaaa aatatttttc atatctattg acttttaggg
    36721 gtgaaatttg gtatgatagt aggcggtatt gtttacccca tttgaaaggc cccggaacct
    36781 tccaaatact tttcgatggg aaggaacacc catcaccgta aacaaaaatc gaactatata
    36841 taggagaaat catgaacaaa acaacattta tggctaaacc aggccaagtt gaacgtaaat
    36901 ggtacgtagt tgacgcaact gatgtaccac ttggacgtct ttctgcagta gttgctagcg
    36961 tacttcgcgg aaaaaacaaa ccaacattta caccacacac tgatacaggt gacttcgtga
    37021 ttgttatcaa tgctgaaaaa gttaaattga ctggtaaaaa agcaactgat aaaatctact
    37081 acactcactc aaaccaccca ggtggattga aacaaatctc tgcaggtgaa cttcgttcta
    37141 aaaatgcagt acgtttgatt gagaaatcag ttaaaggtat gcttccacac aatacacttg
    37201 gacgcgctca aggtatgaag ttgaaagtat ttgttggagc tgagcacact catgctgcac
    37261 aacaaccaga agttcttgac atttcaggac ttatctaagg aaaggaacaa ataaagtatg
    37321 tcacaagcac aatatgcagg tactggacgt cgtaaaaacg ctgttgcacg cgttcgcctt
    37381 gttccaggaa ctggtaaaat cactgttaac aaaaaagatg ttgaagagta catcccacac
    37441 gctgaccttc gtcttgtcat caaccaacca ttcgcagtta cttcaactgt aggttcatac
    37501 gacgttttcg ttaacgttat aggtggtgga tacgctggtc aatcaggagc tatccgtcac
    37561 ggtatcgctc gtgcccttct tcaagtagac ccagacttcc gcgattcatt gaaacgcaca
    37621 ggacttctta cacgtgactc acgtaaagtt gaacgtaaga aaccaggtct taagaaagct
    37681 cgtaaagcat cacaatttag taaacgttaa ttcgaaagaa ttactatact tatacagagc
    37741 acctttcggg gtgttctttt tttatacttt cttactaaat tggtgcaatt gacacagttg
    37801 ttgcgacttt agtcgcttac aaatgtggct gcaacctgac atggtcagtt gcctcaaaac
    37861 gttaatcaat acgattatat caacgtttca aagcactcaa gggtttacct tatttttata
    37921 gtaatgtgaa ataagaatag gacaaaccga ggatagtcaa atcgaattct aacaatgttt
    37981 tagaagtaga ggtgtactat tctagtttca atctactata ttatggataa tgcaagattc
    38041 catagaatgg gtaagttaga actcttgtgt gaagagtttg ggcataaact tttacctctt
    38101 cctccctact cacctgagta caattctatt gagaaaacat gggctctttt gtcctgctct
    38161 tgtttcaatt gactataaat cgctataaga aaaaatcatt ttattggtat aaagaagtga
    38221 ttgaaagtaa tggcgaaacg ttagataatt agttcataaa aaacaagttt agatcctcat
    38281 ctaaacttgt ttttttaaaa ttgaaggatg attttgaagg atataagatg acattgacta
    38341 ttcatgtata ttataaaggt gatggagata gtgcaataaa gtttgcaaga gaaatgcttg
    38401 atagtggcct tgttgaagaa attagaaatc aaaaaggtaa cttgaaatac gaatattttt
    38461 taccaattga aaaagaggga actattctcc ttattgatca gtggataaat caagaagctt
    38521 tagatgaaca tcatcaatca aagacaatgc agaaaatctt agatttaaga aaaaaatatc
    38581 acttgcagat gcaagttgaa cgttatatag aagatgattc tgggatgcca gaaagcgata
    38641 agtcgtttat agacacaggg aattagaatt attgtgagag tttttgtagt ttgaaagtat
    38701 tgaaaatcgt aaagatatca ttacgagaat acaagaagat attgttctat ttccattaaa
    38761 aattacttct tttcttaaca ataaggaaaa agaatgcgtt ttcatctttt ggtttgaggt
    38821 ttataataag agtatcaaag tcaggaggaa aaaagatgac tacttttaaa gatggatttt
    38881 tatgggtggt gctgttgctg ctcatcaact tgaaggtgga tggcaagaag gtggcaaggg
    38941 aattagtgtt gctgatgtta tgactgctgg tcgtcatgga gtagctcgtg aaattacttc
    39001 gggagtttta gagggtaaat attatccaaa tcatgaggcg atagattttt atcatcgtta
    39061 taaagaagac atagcacttt ttgctgaaat gggattcaag tgcttccgta cctctattgc
    39121 atggacgcgt atctttccaa aaggtgatga gttagagccg aatgaagaag gattacagtt
    39181 ttatgataat ctttttgatg aatgcttaaa gaatggtatt gaacctgtca tcactctatc
    39241 tcattttgaa atgccttatc acttagtgac cgaatatggt ggttggaaaa ataggaaatt
    39301 gattgatttc tttgctcgtt ttgcagaagt cgtatttaaa cgttacaaag ataaggttaa
    39361 atattggatg actttcaatg aaatcaataa tcaagcgaat tatcaggaag attttgcacc
    39421 atttactaac tcaggtattg tatatgagga aggtgataat agagaagcaa ttatgtatca
    39481 agcagcacat tacgaattag ttgcttctgc acgagctgta aaaattggtc atgagattaa
    39541 tccagatttt caaataggtt gtatgattgc gatgtgtcca atttatccag ctacttgcaa
    39601 tcctaaggat atcttaatgg caatgaaagc tatgcagaag cgttattatt ttgctgatgt
    39661 gcatgtttta ggtaaatatc ctgagcatat tttcaagtat tgggaacgaa aaggtatttc
    39721 agttgatttt gctgcccagg ataaagaaga tttacttggt gggactgtag attacattgg
    39781 tttcagttac tatatgtcct ttgctatcga ctctcatcgt gaaaataatc cttattttga
    39841 ttatcttgaa acagaagatt tagtgaaaaa taattatgtt aaggcttctg aatgggagtg
    39901 gcaaattgat ccagaaggtt tgcgttatgc gttaaattgg tttacagacc actatcactt
    39961 accactcttt attgttgaaa atggttttgg agctatagat caagttacag cagatggtat
    40021 ggtacatgat gattatagaa ttgaatatct agatgcccat attcgtgaaa tgaaaaaggc
    40081 tgtagttgaa gatggtgttg atttaatggg ttatactcca tggggatgta ttgatttggt
    40141 ttcagctggt accggtgaaa tgcggaaacg ttatggcttt atttatgtag ataaagatga
    40201 taatgggaag ggaagttata atcgttcccc gaaaaaatct tttggctggt ataaggaagt
    40261 tatttcatct aacggtgaat cagtagaata gtataaacaa actgagatta ttctcagttt
    40321 gtttagcata ttgaggtgac atatgattgg aagtattgca gcaattttaa caacatttgc
    40381 atttttacca caagtttttc gtgtagttaa gacaaaggac acaggatcta ttgctctagg
    40441 tatgtatgtt atgcaagtta ttggtattgc attgtggctt gctcatggta ttcgtatagg
    40501 agacttgcct ttgattttag caaatagtgt ttcatttcta ctctcaggaa taattttatt
    40561 ttataaattg aagtataaat aatttttttc catatcattt aggaaaatga gggaattgtc
    40621 attggaaacg ctttatttta taataaaaat agataacaaa taagccaact tagcacagct
    40681 ttgattggat ttaagaaaag gagaaaatat tatggcaaaa gctttaatta tttgtgcagc
    40741 aggaatgtct tcatcactta tggcacagaa aacaacagag tttctaaaag gaaaagggaa
    40801 agatattgta gttgatgcta ttagtgctac tgaaggaggg aaagctatcg cagcagcagc
    40861 ttttgatttg tatcttgtca gccctcaaac aaaaatgtac tttaagcaat ttgaagaggc
    40921 tggttctaaa gcaggaaaac cagttgtaca aatacctcct caagcctata ttcctattcc
    40981 aatgggaatt gaaaaaatgg ctaatttgat tcttgagaat atttgatgaa cacatgaaat
    41041 gtcaataaat atttaagtta agataaattg ttttgagttt gatataaatt gatttaagtg
    41101 tataatatgc ttcaatatat gaaaacatac gttttaggag ggaatgaatg tgttaaacat
    41161 taaagagaaa gatatccttc aatttttaat aaaaaataag gaacgttttg ttacaagcaa
    41221 agaactagca gaatatttat cctgttcaga tagaactgtc cgtaatgtac tgaaattaat
    41281 tgagaagaca atgattattc aaggagtccg gttgatttca aaacaaggtc aagggtatca
    41341 aatatttttt gagaatcaag gcgcttacca ggagtttaga caaacttatg aactggaaga
    41401 agactatacg aaaactgcgg tttcaaaagg tgatgatcgt ttagtattta tcttaaataa
    41461 attattattt gagcaagttc cagttctttt tgatgattta gctgatgaac tttacgttag
    41521 tcgttcaaca ttatctcatg atttcagaaa gatacgagtg atgttatcag agtataattt
    41581 gtccattgag agtagggcga ataaaggagt ttatgtctca ggcgaggaac gtgataaacg
    41641 acgttttatc ataaattatt tcctagagaa tcaatttttt aaaacaatac attgctatgt
    41701 aaaatttaac ttttttgatc aaactgttcc attagaagaa tttgctagaa ttgttttgga
    41761 tgaatgccaa gaggccaacc taaaactatc tgattttgta ctacagaatt tagtagttca
    41821 catagcattg tctgtgattc gtttaaaatc cggatttgaa ataaaaaata tagactgtca
    41881 gatgactgat gatgcaacag agagaaaggt tgcccaaaga attctttcta aagtaagaga
    41941 agtaacaaat caggaatttc cagttcagga aatagactac attactttgc atttgttagc
    42001 taagagtcaa caatgtcaaa aaaatcagaa gaatatttct gaagaagttt taaaaaaatc
    42061 tttatttaaa acatttcaga atttaggatt agatgatatg tataactttt cttcagattt
    42121 ccaactaatt gaaggattga taactcatct aatgacacta caagtacgtt tagaaagccg
    42181 gattacctta aataaccctt tagtagatga aattaaacag aattatagtg atatattctt
    42241 tatgactaga gaaattcttg caaatatgga caagttcttg gagtggacaa tatcagatga
    42301 tgaagtagca tatgtaagtc ttcacttttt agctgctatg gaacgtagca aagagagtac
    42361 taagtttaat attcttgcta tttgtgcaac aggatttggt gcagcccaaa tgttaagaaa
    42421 tcgtttggaa acggagtttg ggaagcgagt agaagttgtt gatgtaatag gctattatga
    42481 attgaatcaa gaaaaactta aaggaataga ttttatagtg tcagctgttg atttatcaaa
    42541 tctatatttt caaatcccag tttttaaagt tagtgtgttt cttaagagtg atgagatgga
    42601 aatgattaga aaagctatgg ttcagatgca agtttctagt tatgtacaat catcaaagat
    42661 taacaaattt gaaaacaacg gctttagaca gtattttagt aaagaaaact ttttaatatg
    42721 tactgaatca gacaaggtaa atttacttga aaagatggtt gagagtttat ctgttggtga
    42781 atcaaatgag tttgaacaat ctttacttta tggaattaaa cagcgcgaag aattaagttc
    42841 agttgttttt tctgaaaaaa ttgcagttcc gcatcctatt cagccctttg gtacagaggg
    42901 aaaggtttcg gttgcaattt gtaaagattc gttactctgg gataatcaaa gttcacatgt
    42961 tcagctagta tttcttctat ctccatcaat atatgggaac gaaggtttgg caactgtgac
    43021 taaaaagata gtctctctga cagagaatga tgaattgcaa aatcagctaa tatcttgcaa
    43081 taactttgaa gattttatta acatatttga gaagataaaa taggaggttc atatgaatca
    43141 agaggaactg caggttgcag catttgaaat tatcctgcat tcgggaaatg caaggtcaga
    43201 aatacatgaa gcatttgcaa aaatgagaga aggtagtttt gatgatgcag aaagtaaatt
    43261 aaatcaatca aatgagataa ttcttgaagc gcatcatgca caaaccaaac tcttgcaaga
    43321 atacgcaagt ggagtggaaa ttaaaattga aattatcatg gtacatgctc aagatcattt
    43381 aatgaccact atgacattat tagaagtagc aaaggaaatg ttagctcttt ataagaaagt
    43441 taactaaata tgtgttgtta tataaggagg aaatgatatg gataaaaaag aacgacaaaa
    43501 gattgaacaa caacgtcgag agatggctct aactaatact tttttcaatc gatatcttct
    43561 tctacgttat tcaatagcac tcttcttttt tgggaatatt tattggcttt tgaatcagtt
    43621 tattagtccc tcgcctatta ttattttccc cattatgctc atagtatttt ctattttagc
    43681 aactattgaa caatttaaac tttatggaaa taggaaagaa aagttgggaa taacactaat
    43741 gtttgttaga atacaaatac ttatttcaat aggattactt gttttaactt ggacaagttg
    43801 gtttaagaat ctttttccga tttttgaaaa taaccaagta gcacgtttat ttgtttttgt
    43861 agttcttcta ttaggtttag ttctgagttt gttagacatt agaagaatta aaaaaattta
    43921 taaacgaaca gataaggctt atcaacaatt tgtccaattg gaaaagaact cacttagttt
    43981 ataatcctga tctagtataa tttgtatttg aaactagtct ttagaaagta aaaattatta
    44041 tgttttatta aggaggtcta tttatggatc aacaaaacgg gttgtttggt tttcttgaaa
    44101 accatgttat gggaccaatg ggcaaacttg ctcagtttaa agtagtgcgt gctatcacgg
    44161 ctgcaggtat ggctgctgta ccatttacta ttgtaggatc aatgtttttg gtattcagta
    44221 ttttgccaca agctttctca ttttggccaa ttgtggcaga tattttctct gcttcatttg
    44281 ataaattcac atcactttac atggttgcaa actatgcgac tatgggttct ctatctcttt
    44341 atttcgttct atcacttgca tatgaattga caaaaattta tgcagaggaa gaagaactca
    44401 atatgaatcc tcttaatggt gccttgctcg ccttgatggc ttttgtcatg acagtaccgc
    44461 aaatcatttt tgatggtgga atgatgaaga ctgtgacaag tctaaaagaa ggtgcagtaa
    44521 ttgcagatgg atgggcaatg ggaaatggag tcgcacgttt tgggacaaca gggattttta
    44581 ccgcaatcat tatggcaatt gtgactgttc ttatttatcg tatgtgtgtt aaacataatt
    44641 gggttattaa aatgcctgaa gctgttccag aaggagtttc tcgtggattt accgctttgg
    44701 ttccgggatt tgttgttgca tttgttgtta tctttatcaa cggtcttctt gtagcaatgg
    44761 gaacagatat ttttaaagtc attgcaattc catttggttt tgtatccaat ctgactaatt
    44821 cgtggattgg tttaatgatt atttatctac tgactcaact actttggatt gtaggtatcc
    44881 acggtgcgaa cattgttttt gcatttgtta gtccaattgc tcttgctaac atggctgaaa
    44941 atgctgctgg cgggcacttc gctgttgcag gtgaattttc taatatgttt gtaattgcag
    45001 gtggttctgg tgcaacttta ggactatgtt tatatattgc ttttgcctct aaatctgaac
    45061 agcttaaagc aataggacga gcatctgtag ttccagcctt atttaatatt aatgaaccat
    45121 taatttttgg attacctatt atctataatc cagccttggc tataccattt attttagcac
    45181 caatggttac tgctactatt tattacgtag cgaattctct aaactttatt aagccaatta
    45241 tcgcacaggt tccatggcca actccagtag ggattggagc tttcttaggg acagcagatc
    45301 ttcgagctgt attagttgct ctagtatgtg catttgcagc attcctagtc tatcttccat
    45361 tcatccgtgt atatgatcaa aaattggtga aagaagagca aggtatctaa taagtaaaaa
    45421 agtatattcg atgatagaat ccatatagtt taaataatga gtgttaatat tagcagtgaa
    45481 gaggtctttt taagatattc ttctctgctt tttcatattt tttcgctatg tagggtatga
    45541 agcaaaatag aaagtagttc gaatagttga taaacaggaa actgctgtta tttaaaaaaa
    45601 aacaataaag taaagtatgt tatcgtagaa tacgatacaa tagtaaaaaa gcaaaaagaa
    45661 tgcgttttat atttgggttt gaggtttata aaataggata agcgtgctga aaacttagat
    45721 atgacaaaca aaataaaatt tttaaaagct acagagaaac atggtataat gtatctaaag
    45781 gaggtagcat atgtccttag atatagataa agaaaagatg acaatcatgg gaatagcttt
    45841 tgaaaacaga tccgttttta agagtgtttg gtatgcttta agtacaaata tgattgaagg
    45901 atggcgacct acggttagtg atgttgaaaa attacgagat gaagctcttg ctctggggat
    45961 gacttaatga agcgcaactg ttatgaatct tatgactatg ttgatccgga taatttatat
    46021 accgatccgg gttcttcagt tctaagaaat aagcaggaag gaaaaaagca cgtgagcttg
    46081 aatatcgtat gattgctagt aagagtttga aattatttat caatcctatc ttagttaata
    46141 gtttaaaagt agtttgtttc acaactgcat aagcttagaa aagttgaaaa gtgataactc
    46201 tttaataaac tcttggtttg ttaaaagata ttttgtccac tgcatttttt caattgacta
    46261 ttatttgtca tagatataac agatagaaca ttgcattcag aataatgaaa aacgcatcaa
    46321 aaatggtgcg ttctgttttt atgctaccat aaaaggagga aaacaaattg aaaattttta
    46381 agggagagtt ttatcgaatc tctgtattaa cagacaagct agtaaggtta gaatactctc
    46441 gaactggaaa ttttgaggat agaacgacac aacttatcta taatagagat tttggccaaa
    46501 tttcgttaga ttatatcgag acatcaaatg tactagatat tatgacggac tattttcatc
    46561 tgcactttaa taaaggagaa tttaacgccg aaaatttatt tatagaatta aaaggaaatt
    46621 ttgccgtata tggtagtcgc tggtattttg gtgaatctat tgaaacgtta aaaggaacag
    46681 ctcggactct ggataaggca gatggagcaa tctcgttaga agatggaatt attagccgaa
    46741 atggtatagc cttattggat gattctcaag gatttatttg ggatgaacaa tctggttata
    46801 ttgagagaga aaatcaaatt gacctgtatt tctttgccta tgggcatgat tatagaggag
    46861 caatcagaga cttttaccat ttgactggtt caacaccctt gttgccaaga tatgctttag
    46921 gcaattggtg gagtagatat tggccttata cgtcggatga atacttggat ttaatagaca
    46981 gatttgaaac agagaaaatt ccattatcta tcggtgtgtt agatatggat tggcatacaa
    47041 ctgacattcc agctcgtttt ggaagtggct ggacaggata tagttggaat agaagcttaa
    47101 taccaaatcc agaacagtta ttgcaacaac ttcatgatag aaagttaaaa ctctccttaa
    47161 atgtccatcc tgctgatggg atacgggctt atgaagaagc ttatcctcaa atcgcagaac
    47221 ggttggggtt aaatgtagaa ctagaagaac ctgctatttt tgattttttt aatccctctt
    47281 ttagggaagc ctactttaaa gatgttcatt atgagctaga aaagcaggga gtagattttt
    47341 ggtggattga ctggcaacaa gggacacaag gtatgctaga tccactttgg cttttaaacc
    47401 attatcacta tcaggatagt tgtaaaaatg cagaaggtgg tttgatttta tcaagatatg
    47461 caggtcctgg tagtcaccgc taccctgttg gtttttcagg ggatactatt attagttgga
    47521 attccttaag gtttcaaccc tattttacag cgacagcatc taatatcggt tatagttggt
    47581 ggagtcatga tatcggtgga catatgttgg gggattatga cgaagagcta caaactagat
    47641 ggctacagtt tggtgttttt agtccgatta ctcgattaca tagttctaga agtcctttta
    47701 atagtaaaga accttggttc ttttcagaaa caacatctaa gattatgaag aaataccttc
    47761 gtttgagaca tcagatgatt ccctatctat ataccatgaa tgtaaagaca catgaggaag
    47821 gtgccccatt aatcagtcca atctattatt tctatccaga gaatgatgag agctataatg
    47881 ttccaaacca atactttttt ggaacagaac tgatggtggc tcccattgta gaaaagatgg
    47941 atttgacatt ccaatctgca aaagtagatg tatggttccc tgaaggtgaa tggtatgact
    48001 tcttttcaga gaaaaaatac acaggtggtg tgaagttaag tgtttatagg gacatctcga
    48061 ctacgcctgt gtttgcaaaa agtggtgcaa tcattccctt ggttggttct gagataggta
    48121 tgggtgttga tttacctgag gttgtagatt ggtatgtatt cccagggaaa caacattctt
    48181 ttgaaatgct tgaagatcaa aatggtcaaa gatataaaac aagattatca atcgattggg
    48241 aaatgggaat ggtagagtta gcattacaag gagattctag tatcgttcca agcaatagaa
    48301 aacatagaat tcattttaaa ggaacgaatg tgtctataat tgaattgcca aataagaatg
    48361 atacagctaa atttgaatgg aaagataata aaaggacatc tttaaatgac gaagttttta
    48421 gactactaaa gacagcttct cttccatatg aattaaaaga tagattgtta aatcaattca
    48481 tcaatgcgaa aaactctcat gacttaatga atatcttgca tcatcaggat aaggaattga
    48541 gagggcgttt gttggaaatg atatttacta gccaaaacta attgatataa ttagaaagtc
    48601 atttgtttag tgtatatgaa gattctgtat ggtattcgtt atcactggtc acattgaaaa
    48661 tgtgaaataa gcacctacaa catagacttt acaacacttc atgtttcata tcatggggtg
    48721 tttttctatt taagtcaaag ccaatcaaaa aatctcacta ttcatcaggt taaaggaaac
    48781 ctaatcatag tgagattgtg aattatagta gagtttgtat cgcctcttca atttgttttg
    48841 ggtctgtttt tgaagaaaag cgttcaaaga cttgcccatc acgactaatg agaaacttag
    48901 cgaaattcca ttcgattcgt tttcctagtg ggccagattt atggtctttt aaccagacat
    48961 agagagggtc tgcttcctta ccgttgacct taatcttggc aaaacgtggg aaggtggttt
    49021 gaaaatgtag gctacagaag gcgttgattt cctctgcgct gccgggtgct tgtcccataa
    49081 actgattgca agggaaatcc aatatttcga agccctgatc ttgatagcgt tcatagagtt
    49141 cttgaagtcc ctggtactgg ggcgttaaac cacatccagt agcagtgttg acaatcaaga
    49201 gaactttacc acgatagcta tccaagggag ttgcttggtt gttttggttc aaaacggaaa
    49261 aatcataaag tgaagtcatg agggcctctt ttctttttct acattgtaac agtttttact
    49321 tttttcgtcg agtcggatgg aagatattgt tgaagaataa gccctcaata tgatagaaac
    49381 cgtttacaaa taactttaaa aatggtatga tttaattaaa ccggtttact tagttgctat
    49441 aaatctctaa tttgagattt agttcctatt gattttacaa tatgtttatt ggagtgtata
    49501 catgcaaaca aaaacaaaga agctcattgt gagtttgtct tcacttgttt tatcaggatt
    49561 tttattaaac cattatatga cagttggagc ggaagaaacg actacgaata ccattcagca
    49621 aagccagaag gaagttcagt atcagcaaag ggatacaaaa aatttagttg aaaatggtga
    49681 ttttggtcag acggaggacg gaagcagtcc gtggacagga agcaaagctc aggggtggtc
    49741 agcttgggta gaccagaaga atagttctgc agatgcctca attcgagtca ttgaggctaa
    49801 ggatggggct atcactatct caagccctga gaaattaagg gcagcggttc accgtatggt
    49861 tcctattgaa gctaagaaaa agtataaact gcgtttcaag attaaaacag atcataaagt
    49921 cgggattgcc aaggttcgta tcattgagga aagtggtaag gacaagcgat tgtggaattc
    49981 tgcaacgacg tcaggaacaa aggactggca gaccattgaa gcagactata gcccgacttt
    50041 agatgttgat aaaatcaagc tggagttatt ctatgaaaca ggaactggga ctgtttcctt
    50101 taaggatatt gagctggtag aggtagcaga ccagctttct gaggattctc aaacagataa
    50161 acagcttgag gaaaagattg atttaccaat tggaaaaaaa catgtttttt ctcttgcgga
    50221 ctatacttat aaggtagaaa atcctgacgt tgcttcagtc aaaaatggaa ttttagaacc
    50281 tcttaaggaa gggacaacca atgtcattgt cagtaaagat ggcaaggaag tgaaaaagat
    50341 tcctttgaag attctagcct ctgttaagga tgcatacaca gaccgtttgg atgactggaa
    50401 tggcatcatc gctgggaatc aatactatga ttctaaaaat gaacagatgg ccaaattaaa
    50461 ccaggaattg gaaggaaagg tagctgatag cctatctagt atttcaagtc aggcggaccg
    50521 cacctatttg tgggaaaaat tttcaaatta taaaatgtct gcaaatctga ctgccactta
    50581 tcggaaattg gaggagatgg ccaagcaagt gaccaatcct tcttctcgtt attatcaaga
    50641 tgaaactgtc gttcgaacag tcagggattc catggaatgg atgcataaac atgtctacaa
    50701 tagtgaaaag agcattgttg ggaactggtg ggattatgaa atcggtacac ctcgtgccat
    50761 caacaatacc ttgtctctga tgaaagaata cttctctgat gaggaaatta aaaaatatac
    50821 agatgtgatt gaaaaatttg taccagatcc cgaacatttc cgaaagacga ctgataaccc
    50881 atttaaggct ctaggtggaa acttagttga tatgggaaga gtaaaagtaa tagctggttt
    50941 actgcgtaag gatgatcaag aaatttcttc taccattcgc tcgattgagc aagtgttcaa
    51001 gttggtagac caaggtgaag gtttttatca agatggatcc tatatcgacc ataccaatgt
    51061 tgcctatacg ggtgcttatg ggaatgtttt gattgatggc ctgtctcaac tgttgccagt
    51121 cattcaaaag accaagaatc caatcgataa agataaaatg caaaccatgt accactggat
    51181 tgataaatcg tttgctcctt tgctggtgaa tggagagctg atggatatga gtcgtggacg
    51241 ctcgatcagt cgtgcaaata gcgaggggca cgtggccgca gtagaagtac taagagggat
    51301 tcaccgaata gcggatatgt ctgaaggaga aaccaaacaa cgtttgcaga gtcttgtgaa
    51361 gaccattgtt caatcggata gttattatga tgtctttaag aatttgaaga cttataagga
    51421 tatcagtttg atgcaatcct tgttaagtga tgcaggagtc gcaagtgttc caagaacaag
    51481 ttacctatct gcctttaaca agatggataa aacagccatg tacaatgcag agaaagggtt
    51541 tggatttggc ttgtcactct tttccagtcg taccttgaat tacgaacaca tgaacaagga
    51601 aaataaacgt ggttggtata cgagtgatgg gatgttctat ctttacaatg gcgatttgag
    51661 tcactatagc gatggctact ggccaacagt taatccatat aagatgcctg gtacaacaga
    51721 gacggatgct aagagagcgg atagcgatac aggtaaagtt ttaccgtctg ctttcgttgg
    51781 aacgagcaaa ctagatgatg ccaatgcgac agcaaccatg gatttcacca actggaatca
    51841 aacattgact gctcataaga gctggtttat gctaaaggat aagatcgcct ttttaggaag
    51901 caatatccaa aacacttcaa cagatactgc tgcaactaca attgaccaga gaaaactgga
    51961 atcaagtaat ccatataaag tctatgtcaa tgataaagaa gcctccctta cagaacaaga
    52021 aaaggattat cctgaaaccc aaagtgtctt tttagaatca tccgattcga aaaagaatat
    52081 tggttacttt ttctttaaga agagttcaat cagtatgagt aaggctttgc aaaagggagc
    52141 ctggaaggat atcaatgaag gacagtcaga caaggaagtt gaaaatgaat ttcttacgat
    52201 tagtcaggct cataagcaaa atggagattc ttatggctat atgctcatcc ctaacgtggg
    52261 tcgtgccacc ttcaatcaaa tgataaaaga gttagaaagt agcctcatcg aaaataacga
    52321 aacccttcag tctgtttatg atgccaaaca aggagtttgg ggcattgtga aatatgatga
    52381 ttctgtctct actatttcca accaattcca agttttgaaa cgtggagtct ataccattcg
    52441 aaaagaaggg gatgaatata agattgccta ctataatcct gaaacccagg aatcagctcc
    52501 agatcaggaa gtctttaaaa agctagagca agcagctcag ccacaagtac agaattcaaa
    52561 agaaaaggaa aaatctgaag aggaaaagaa ccattcggat caaaagaatc tccctcagac
    52621 aggagaaggt cagtcaatct tggcaagtct agggttcttg ctacttgggg cgttttattt
    52681 attccgtaga ggaaagaaca actaatttgt tcatcatcta gatgaattac atgaaactgt
    52741 ggaaaataga aaaaatccga agaaggccaa atatcttcgg atttttcttt taaaaaagat
    52801 aagttgatac ttatcttttt tacttcatta tgtgactata gcgttttgaa actagaatag
    52861 gacgtcataa ctgctaaaag atttctataa attcatttga ttttcctaat caatttgttc
    52921 gtatcctatt tcactccact atattagtcc gtctcgctcc gtgaggtgcg agacaaaaca
    52981 accacccgct atgcgggtgc gcgtcgaagg ttataccaaa aaaactccaa acgcgataca
    53041 ataaaggtgt tcaatccact tgtaaagcga aaggagaaaa aatatggcac aaaaggctca
    53101 tagtttatct cacacaaagt ggaggtgttc tatcacattg tgttcacccc taagtataga
    53161 cgaaaagtca tctataatca atatagaagt agtttaggcg aaatatttca tcgcttgtgt
    53221 agttataaag gtgttgaaat gatcgagggt cacttaatgc cagaccatgt acacatgtta
    53281 gtcagtattc cactaaggct aagtgtttcg agtttcatgg gttatttaaa aggcaaaagt
    53341 gcactcatga tgtttgacaa acacgccaat ctcaagtaca agtttgggaa tcggcatttc
    53401 tgggcggaag gttattatgt aagtccagta gggcttaatg aagccacaat taagaaatat
    53461 agtcaagatt aaagaaatta tccagtggat gatttcttca cgagtatgaa aatttgagaa
    53521 ctagtaaagt atgatatata gtaaaatgaa ataagaacag gacaaaatcg atcaggacag
    53581 tcaaatcgat ttttaacaat gttttagaag tagaggtgta ctattccagt ttcaatctac
    53641 tatagcacta gataaattga gtgtaaaaga atatgaggat ccctttaggg atagtggtaa
    53701 gtaataccaa agtctcttaa agaggcaagt gacgagtcaa gagcaataag gcttgaacaa
    53761 cgtgaaagcc agcgtcttta ggcgctggct gatgatttgg gcttatagct ctgagataaa
    53821 ccacccgtta gacgggtagt tatgatttta tctgagtgta acatactgtt gggcaatctc
    53881 gctgatgcgg tcaaagttgc cttgggaagc gagtttattg agttcgccac caattccaac
    53941 ggcatctgca ccagcagcga accattgagg gatgttgttt aggccgactc ctccggttac
    54001 cattacggaa acttgtggga tcggtgcctt gactgcagag atatatgctg gactgagagt
    54061 actacctggg aagagtttga tgatttcact accggcttca agtgcagtcg tgatctctgt
    54121 gagggtaata cagcctggaa tgtacggtgt gctgtagaga ttgcacattt tcgcagtttc
    54181 agcatggaaa gatggagaaa caacgtaatt tgctccagct agaatggcat ctctagcagt
    54241 tacggcatca agcacagtac ctgcaccgat acaaacactc tgatcgtcct gatacaagtc
    54301 tacaagttcc ttgatgattt gtcctgcata ctgattggta taggcgattt caatagcttt
    54361 gataccgccc ttgatacaag caatcgaggc ttgtagtcct tcttcctttg tatttcctcg
    54421 aatgacagcg acaattttct gtttttttag ttcaataatc gtatctgatt tggtcatgta
    54481 attctcctaa cgaatgatat cttgtgcatt tgccagtaaa ttttcaatac tagttgcgga
    54541 agtggagaga tggtctcctg gaagagtgca tttgagagtt gcgctcgcaa ctgcaaagtc
    54601 aatggtagtt tttagggagg aatgatggag tagttggtaa agggcaccag atataaaggc
    54661 atccccgcta ccaattcgtt gatagactgc agtttttagt tggacagact cttcaaatcg
    54721 ttcttccaga gcataggctt gatagacatt tttgtcttgc tcatcactag atcggagggt
    54781 atggaaaata gccttgaaac cataggtttc ttttaaaagt cgcatgcgat tttccacctc
    54841 ttctaggcta gcactgtctc ttggaaacat ctctagattt tggtcatcaa tcatgagagg
    54901 atcaataccg aagcaatagt cagtaaaacg tgcaaactta gaaaattcat acttggcttc
    54961 tagggctgaa atcatctttg ttctcagatt gagatccatt gaaacgacaa ttcctcggcg
    55021 cttggcttct tccaagagta ggagaaggat cgcacggacc tcttgaccga tagctatggt
    55081 gattccacta aaatgaaaat ggctaatccc ctgaaagaga gaatccatat ctagcatgtt
    55141 tggccgaatc tggctgatac tcgtatgctt acgatcgtag aaaacttcac tttgacgaca
    55201 accaaagccg ttctccaaat agtagaggcc gattcgatcg ccaagccgac agattgaact
    55261 ggtatcgatt tggtgctgtt tcaagaatgt gagaaaacga tctccaatct cgttggcagg
    55321 gagtgcggta aagactttcg ttgagatacc cagggcttgc aaattacaag cgatgttaat
    55381 ttctgatccg ccaaaataag tcgaactggc aacatgatcg ccgatactgg tggcatctaa
    55441 tggtgagatt cgaattaatg gttcgccaaa cagtaatatt ttcgtcatcc attagttcct
    55501 ttctggttta gaatagcttt acttggctaa tacttctttc aaataagcag cgacttcatc
    55561 atcttggcag ttttcaaaga agtattcttg gaagtatttg ccagagatgg tgtctttgag
    55621 gaagtcttgg tcgattgttt taaggatggt catcaaatca ttgtgggtga tttgtttcac
    55681 ctcgtttaag atacgagcgt tgcgttgttc agggattaca cgttctcttg ggtagccacc
    55741 gcccatttct tcagcaaata agcgttcaaa catcaatttg agggtcagtt ctgcccccca
    55801 gccaaatcct ttggcataag ggatagacaa ggcgttacca ccattgattt gagaataaag
    55861 gtaagcgtca gttgggtcca ctgctagacc acagacaaca ccagggaagc tgtttaaagc
    55921 aagcatagcc cctacacccg taccacagcc ggtaacaaca aagtcaactg cctttgtatt
    55981 taaaaggatg gcagccatta gtccgttctg cacataagtt aattgacttt ctccttcttc
    56041 tccacgcata ccatagttaa ataattggta gtctttttta tctgtcgctt cttttagact
    56101 atcgtaaata atgtgattct tgctagcttg actattttca ttgattaatg cgattttcat
    56161 aagatcttct ttctattttt actcaggttg ttttccgatg taggctaaga taccgccatc
    56221 tacatatagg atgtggccat tgacaaaatt gctggcatca ctagcgagaa agacagcagg
    56281 gcccatcaaa tcttcaggat ttccccaacg tgcagcaggt gtttttgcaa tgatgaactg
    56341 gtcaaatggg tggcgagaac catcttcttg caactcacga agaggtgctg tttgaggagt
    56401 ggcaatataa cctggtccaa ttccgttaca ttggatattg gctccaccgt attcagacgc
    56461 aatgttgcgg gtcaacattt tcaagccccc tttagcagca gcataagcgc taactgtttc
    56521 acgtcccagt tcgctcatca tcgaacaaat attgataatc tttccatgcc ctttctttat
    56581 catagaagga ataactgcct ttgaaacgat aaatggtgcg tttaagtcaa tatcgatgac
    56641 cttacggaaa tcagcggcgc tcatttcgca cattggaact cggcggataa taccagcgtt
    56701 attaacgagg atgtcaatga caccaacctc ttgttcgatt tgcttgacca tggcttggat
    56761 accgtcctcg tctgtcacgt cacagacata tccatgggct tcgatgccaa cttcacgata
    56821 agcttcaatc cctttattga ccagatcttg attgatatcg ttaaagacaa tagtagcgcc
    56881 ggcttcagcg taggatttgg caatagcaaa tccaattcca taagaagcgc cggtgatgag
    56941 agcaattttt ccttttaaag aaaactgctc aattgagaat gatgtatttg tcatttgata
    57001 cttcctttca aatttgttaa gacttctcta taaccaaatt atattctagt aaaccggttt
    57061 tgtcaataaa taaatatttt tatttataaa aagatttgtt ttcctaaaaa aacggaagat
    57121 tttgaaactt ctgtctatta aaatgattaa aaagataatg aaagcgctaa tattttttta
    57181 aaaaaactat tgacaagata aaaataaagg attacaatgg ggaatataaa gtaaaccggt
    57241 aaacctaaac aagaaaggag aaaagatgaa aattgtactt gtagggcatg gacattttgc
    57301 tacagggatt tatagttctt tacaattgat tgcaggcaat caagaaaatg tggaggcgat
    57361 tgactttgtg gaaggaatgt cagcagatga actcaagcaa aaaatcttac ttgcaatttc
    57421 aaatgaagaa gaagttttaa tcctaagtga tctcttggga ggatcgccat tcaaggtttc
    57481 ttctaccata atgggagaaa atccagccaa aacaatgaat gttctctcgg gtttgaactt
    57541 agccatgtta atggaagcag tctttgctag aatggctcat agctttgatg aggttgttaa
    57601 taaatcagta gtggcggccc agggcggagt cgtaaatggt aaagaattgt tttcaacgga
    57661 tgcagaggaa gaggaagaag atttcgaatc gggtatttaa agggtaaaag aatgataaaa
    57721 aaggttacga ttgaaaaaat aaaatcgcct gagcgcttct tagaagtacc acttctgacg
    57781 aaagaagaag tcggccaggc aatcgataag gttattcggc agttagaact caaccttgac
    57841 tatttcaagg aagatttccc gacgccagct acctttgata atgtctatcc aatcatggat
    57901 aacacggaat ggaccaatgg tttctggaca ggagaactgt ggttggctta tgaatacagt
    57961 caacaggatg catttaaaaa catcgctcat aaaaatgttc tttctttcct ggatcgtgtc
    58021 aataagagag tagaattgga tcaccatgat ctcggcttct tgtacacacc gtcttgtatg
    58081 gctgaatata agataaatgg agatggagag gctagagaag caaccttgaa agctgcagat
    58141 aagttgattg aacgctatca agaaaaaggt ggttttattc aagcttgggg agacttgggc
    58201 aagaaagagc attaccgttt gattatcgac tgcttgctca atatccaact cttattcttt
    58261 gcttatcaag aaacaggcga tcaaaaatac tacgatattg cagaaagcca tttctatgct
    58321 tcagctaata atgtaatccg tgatgacgct tcgtccttcc acaccttcta ttttgatcct
    58381 gagacaggtc aaccctttaa aggtgtaacg agacaagggt atagtgatga ttcatgctgg
    58441 gcacgtggtc aatcatgggg agtctatggt attcctttga cttatcgtca cttaaaagac
    58501 gagtcctgct ttgacttgtt taagggtgtg accaattatt tcttgaatcg tctgccaaaa
    58561 gatcatgtgt cctattggga tttgattttt aatgatggta gtgatcaatc acgagattct
    58621 tcagcaacag ctatcgccgt ctgtgggatt catgaaatgc taaaacatct cccagaggtg
    58681 gatgctgaca aagatattta taaacatgct atgcatgcca tgcttcgttc cttgatcgaa
    58741 cattatgcaa atgatcaatt tacccctggt gggacaagtc tcctccacgg tgtgtactca
    58801 tggcattcag gtaaaggagt ggatgaaggc aatatctggg gtgactacta ttacctagaa
    58861 gcccttatcc gtttctacaa agactggaac ctatattggt aggaggagaa atatgacaat
    58921 gccaaatatt attatgaccc gtatcgatga acggttgatt catggacaag gacaactttg
    58981 ggtaaaatac ctaggttgta atacggtcat tgttgccaat gacgaagtaa gcacggacaa
    59041 gatgcaacaa actctgatga aaacagttgt gccagactca gttgccatgc gtttcttccc
    59101 tttgcaaaag gtgattgata tcattcacaa ggctaatcct gctcaaacga tctttatcgt
    59161 tgtaaaggat gtgaaggacg ctttaacctt ggtagaaggt ggtgtcacta tcaaagaaat
    59221 caatattggg aacattcaca atgcccctgg taaagagcaa gtgacacgct ccatcttcct
    59281 gggtgaagag gacaaggcgg ccctcaagga attgagccaa actcatcaag taacatttaa
    59341 tacgaaaaca actccaacag gaaatgatgg agctgttcaa gtcaacatta tggactatat
    59401 ttaaaagagg agatcgttat gtcgattaat gtatttcaag cgattttaat tggattatgg
    59461 acagctttct gttttagtgg aatgctgtta ggaatttaca ccaatagatg tattgttctg
    59521 tcatttggtg tcggaattat tctaggtgat ctgcctactg ctcttgcaat gggagctatt
    59581 ggtgaattgg cttatatggg attcggtgtt ggtgctggag gtactgttcc accaaaccca
    59641 atcggacctg gtatctttgg taccttgatg gctatcacta gtgctggtaa agtcagtcca
    59701 gaagcggctc ttgccctctc tactccgatt gctgtggcga ttcaattctt acaaactttc
    59761 gcctacactg tacgtgctgg tgcgcctgaa acagctatga agcacttgaa aaaccataat
    59821 ttgaagaaat ttaagttcac tctaaatgca acaatttggt tgtttgcctt tattggattt
    59881 accttgggtt gcttgggtgc cctttcaatg gataccttgt tgaaactcgt agactacatt
    59941 ccaccggtat tgcttacagg tttgacagtt gctggtaaaa tgctcccagc tatcggtttt
    60001 gcgatgatct tgtcagtgat ggctaagaaa gagttgattc cctttgtctt gttgggatat
    60061 gtttgtgcag cttatctaaa catcccaaca attggtattg caattgtagg tactatcttt
    60121 gctttgattg aattttataa caagccaaaa acagcgaatc atgtggtaga ggaggaagca
    60181 cacgatgact ggatctaaca aattaacaaa acgtgattat cttaaaacgt ctttgcgggc
    60241 attcttttgt caaaatggat ttaactatag taactatcaa gggttgggat atgccaatgt
    60301 aatgtatcct gctttgaaaa aacactatgg agaggatcag gaaggtttct accaagcctt
    60361 ggaagaaaac tgtgaattct ataataccaa tccacacttc ctgcctttta ttaccagctt
    60421 gcaccttgta atgttggaaa atggccgtcc ggcaaaagaa acacgtagca tcaagatggc
    60481 cttgatggga ccattggcag gtattgggga ttctctttct caattctgtt tagctccatt
    60541 gttctcaacc atcgcagctt cgtttgctca agaaggcttg gttgtcggtc caatcttgtt
    60601 cttccttgcg atgaatacga ttttaacagc gattaaattg tcaactggtc tgtatggata
    60661 caaactagga acaactgtga ttgataaact aagcgaacag atggcaacga tttctcgtat
    60721 tgccaatatt atcggtgtaa ccgtaattgc tggtttggca gcgacatctg ttaagattat
    60781 ggtgccgatt acctttgctg caggggaagt taaagcagac gctaaacaaa gtatcgtaag
    60841 tattcaggga atgcttgata aggttgctcc agctcttcta ccagccctat ttacactttt
    60901 agtttactac ttgatcaaag aaaagaaatg gacaacatat aaactcgtta ttttaacagt
    60961 tatcatcgga attatcggaa gctggcttaa gattatagct taatggatac aacattgttt
    61021 tatggaatag tgattgtctt ggcagtgagt ccccttttac tgtcaagctt tcattctatt
    61081 cgtcagcaaa agttgcttcg caaacagatg gagcaacgac aagagtattt agcttcttta
    61141 acatctggtg atgaagtgtt gttattgtct ggaattcatg gaaaaatcat ttctatcaaa
    61201 gatgacttgg tctccttgca gattgcaaaa ggtgtggtca tctatgtaga aaaggaaagt
    61261 gtaatgggaa agacaaaaga actgcttttt aagtagttct ttttctggta atagataatg
    61321 aaagaagaaa gaagacaatt ttttgaaaga gtcgatggaa accaatgtcg tgattatatc
    61381 ttgtcccact gttcaaaaga ctatgagaaa gtcaagagtt cccttgaacg cttgatggac
    61441 aatcgtttta tgtttgatag tccttgggat atggagcctt gttcaaaaat ccatcaaatc
    61501 cagccgatgg tatgggatca agtatttgaa gatgatccag aatggtctta tatgctcaat
    61561 cgacaagaat atctcttgca gtttatgata gggtatctgg tagaaggaga taagggctat
    61621 attcaaaagt gcaagttctt tctatttgac tggattgagc aggtgagaga atttcgtcct
    61681 caatctttga tgactagaac cttggatacg ggtattcgtt cctttacttg gttgaaacta
    61741 ctcttgctcc tcttgaaatt tgacttgcta gaggaggaag aactagagaa aattttggtc
    61801 agtctagaaa agcagattga ctttatgaaa agccattatc gcgccaagta cacccttagt
    61861 aactggggga ttttacaaac gattccgata cttgcaacct atcatttctt ttcagataag
    61921 atggacctag aagaagctta ccattttgct tcaaaggagt tgaaacagca gatcgagacg
    61981 cagattttag aagatggaag ccagtttgaa cagtcgattc tctatcatgt agaggtttat
    62041 aaagccttgc tggacttgtg tatcttgctt ccggacttgc aagatagttt tcaagagctg
    62101 ctggaaaaga tggcgactta cattcaaatg atgacaggtc tagatggacg gaccttgact
    62161 tttggtgata gcgattctac agaaacgaca gagattttga gcctgtctgc tatggttttg
    62221 aacaaggaag accttcttaa cggtctggat gttaaagtcg atttacttag cctcctgttc
    62281 ctggggcgag aaaaggtcaa gcgactgcag gaatttgaaa agagagcttg gcagcctaag
    62341 ttcaggagct ttgaagattc tgggcatgtt tgcattaagg atgaacatcg ttatctattt
    62401 tttaaaaacg gtccgctggg aagtgcccat agccatagtg acgagaatag tttttgctta
    62461 cagtatcaag gccaaccgat tttcatagat gctgggcgtt attcttatcg ggaggtagat
    62521 gaacgttatc tcttaaagag tgcttggagt cattcgacct gcattgtaga tgggaaagct
    62581 ccggaaagaa tcacgggatc ctgggaatat gaatactatc ctcactccct gttttgtcac
    62641 cataaagaaa gggagggagt gcattatatt gaaggggctt attggtcagc agaacctgat
    62701 ttgccttatc ttcacaagag aaaaatcctc atgttggtag aggatgtctg gctcttggta
    62761 gatgacatca ggtgtcaagg tcagcatgag gcgttgactc agtttatcct tgacaaggat
    62821 gtgacctatc aagatgggaa aatcaatcag ttgagactat ggagtgaagt tgattttgat
    62881 ttggaagata ccatcatttc tcctaaatac aatgagcttg aaagaagtag caaactcacc
    62941 aagcgccaat tctttgagaa tcagatgctg gattatacca tcattgcgca tgagagtttt
    63001 gaaatcatcc gtcattctgt ctaccagaca gatgatcgtg aagtggaaaa tgctctggct
    63061 tttgaagtaa aaaatgacga aacagacaag ctgattctgt tattaagcga ggatatttgt
    63121 gtaggtgaaa aattgtgcct cgttgacgga acaaaaatgc gtggaaaatg tctagtatat
    63181 gataaaataa atgagagaat gattcgcttg cagtgctaga aataggcatt ttgaatagtg
    63241 aatatgttat aataagtatt agtaggaggt gttttagatt ggagaagaaa ctgaccataa
    63301 aagacattgc ggaaatggct cagacctcga aaacaaccgt gtcattttac ctaaacggga
    63361 aatatgaaaa aatgtcccaa gagacacgtg aaaagattga aaaagttatt catgaaacaa
    63421 attacaaacc gagcattgtt gcgcgtagct taaactccaa acgaacaaaa ttaatcggtg
    63481 ttttgatcgg tgatattacc aacagtttct caaaccaaat tgttaaggga attgaggata
    63541 tcgccagcca gaatggctac caggtaatga taggaaatag taattacagc caagagagtg
    63601 aggaccggta tattgaaagc atgcttctct tgggagtaga cggctttatt attcagccga
    63661 cctctaattt ccgaaaatat tctcgtatca tcgatgagaa aaagaagaaa atggtctttt
    63721 ttgatagtca gctctatgaa caccggacta gctgggttaa aaccaataac tatgatgccg
    63781 tttatgacat gacccagtcc tgtatcgaaa aaggttatga acattttctc ttgattacag
    63841 cggatacgag tcgtttgagt actcggattg agcgggcaag tggttttgtg gatgctttaa
    63901 cagatgctaa tatgcgtcac gccagtctaa ccattgaaga taagcatacg aatttggaac
    63961 aaattaagga atttttacaa aaagaaatcg atcccgatga aaaaactctg gtatttatcc
    64021 ctaactgttg ggccctacct ctagtcttta ccgttatcaa agagttgaat tataacttgc
    64081 cacaagttgg gttgattggt tttgacaata cggagtggac ttgcttttct tctccaagtg
    64141 tttcgacgct ggttcagccc tcctttgagg aaggacaaca ggctacaaag attttgattg
    64201 atcagattga aggccgcaat caagaagaaa ggcaacaagt cttggattgt agtgtgaatt
    64261 ggaaagagtc gactttctaa aatgaaggaa aatgacttgc aatttctgtt aagaaataaa
    64321 ataatcccac ctagaacaag ctaggtggga ttatttgcct atgaaatgag aaattatggg
    64381 agcaagctcc taaatcaact gtttttgatc tacttcttta actacttgat aaaagttata
    64441 gaagtaggtc aaacttgaaa tgatggttac gactaggaat attgaaaatt tccattggac
    64501 agggttggtt aaaagttgtg gaaaggatat gaggagaaag aagagggctg cgttgaggac
    64561 aggtatccgt tttgattgta ttttctcaag tcctttattg agcgcaggaa gaaagaggag
    64621 taggagtagt aaaactgtat gagaaacagc tcctgaaata agggcgaaga aaaggaaaat
    64681 actgataaaa acatgaatga tcagtagtct agctagtgat ttcataaggc acctcctaat
    64741 cctggtcttt tttagctctt gcaatacgaa gtgagtcgac aatatgtatc atcactccga
    64801 aaaagaaagc tcccagtata gttttaaaaa tatgttttgt atttagaaga gaactgataa
    64861 aatttggatt ttcacttgtt agggtatcaa tgagtggaat tataaaaaat atcactgttc
    64921 cataaatcga acctgctttc agacctggat aatgtaactg tctcttttct tttttcatag
    64981 ggcacctcct aatcctcatc ttgatttttc ttagtttttg caatgcgacg ggagatgagg
    65041 aactgtatgc tcgctccgaa gaaaatagaa ccgagaatgc ttgatacacc atttcttata
    65101 gtgagaagag aatgaaaata gtcctgacct tcacctatga gtatcctgag aagaggagtt
    65161 ataaaaaaca tccatagacc aaagaacaaa cctgctttca gacctgggta atgtagttgc
    65221 ttactttctt tctcgctcag catgtctgga tcaatagctg taatccctgt ttttttcatt
    65281 tggtaggtga catagccagc agcgatgagg gcaatcacta aaatcagagg aggatagatt
    65341 agagccactt cttgagggta tttataggcc agaaggagtg gaataagatt tccgaaaatc
    65401 atcagataaa agaggacgat aaaaacttgg ttcccaatac tatcggcctc acgccgtttg
    65461 tattcgtcaa ggggaccaga aataccgtat gtgcgtttga tcagtttttc agtgaaggtt
    65521 tcttttttca tgagtttgct ccttttttaa aaatcttcct cccaaaagag actgttgagg
    65581 tcagtttgga ggctgcgggc gagattgaga cagagttcca aggttggatt gtacttgtcg
    65641 ttttcaatca tattgatagt ctgtctcgag acaccgatat ccttggcgag ttcgagctgg
    65701 gaaataccca attccttgcg aaattctttc acacgattca tctgttctcc tttctgattt
    65761 atgtcgtata tatttgacta tattatagtc ttttaaacat aaagtgtcaa gtatttttga
    65821 catatttttt gaagaaatag tagtctcctt gtcctatttg tctgacaagt gcaagctggt
    65881 cggatttgtg gtaaaataga taagatatga caaaagaatt tcatcatgta acggtcttac
    65941 tccacgaaac gattgatatg cttgacgtaa aacctgacgg tatctacgtt gatgcgactt
    66001 tgggtggagc aggccatagc gagtatttat taagtaaatt aagtgaaaaa ggccatctct
    66061 atgcctttga ccaggatcag aatgccattg acaatgcgca aaaacgcttg gcaccttaca
    66121 ttgagaaggg aatggtgacc tttatcaagg ataacttccg tcatttacag gcacgtttgc
    66181 gcgaagctgg tgttcaggaa attgatggaa tttgttatga cttgggagtg tctagtcctc
    66241 aattggacca gcgtgagcgt ggtttttctt ataaaaagga tgcgccactg gacatgcgga
    66301 tgaatcagga tgctagtctg acagcctatg aagtggttaa tcactatgac tatcatgatt
    66361 tggttcgtat tttcttcaaa tacggtgagg ataaattctc taaacagatt gcgcgtaaga
    66421 ttgagcaagc gcgtgaagtg aagccgattg agacaacgac tgagttagca gagattatca
    66481 agttggtcaa acctgccaag gaactcaaga agaagggtca tcctgctaag cagattttcc
    66541 aggctattcg aattgaagtc aatgatgaac tgggggcggc agatgagtcc atccagcagg
    66601 ctatggatat gttggctctg gatggtagaa tttcagtgat tacctttcat tccttagaag
    66661 accgcttgac caagcaattg ttcaaggaag cttcaacagt tgaagttcca aaaggcttgc
    66721 ctttcatccc agatgatctc aagcccaaga tggaattggt gtcccgtaag ccaatcttgc
    66781 caagtgcgga agagttagaa gccaataacc gctcgcactc agccaagttg cgcgtggtca
    66841 gaaaaattca caagtaagag ggaaaaagat ggcagaaaaa atggaaaaaa caggtcaaat
    66901 actacagatg caacttaaac ggttttcgcg tgtggaaaaa gctttttact tttccattgc
    66961 tgtaaccact cttattgtag ccattagtat tatttttatg cagaccaagc tcttgcaagt
    67021 gcagaatgat ttgacaaaaa tcaatgcgca gatagaggaa aagaagaccg aattggacga
    67081 tgccaagcaa gaggtcaatg aactattacg tgcagaacgt ttgaaagaaa ttgccaattc
    67141 acacgatttg caattaaaca atgaaaatat tagaatagcg gagtaagata tgaagtggac
    67201 aaaaagagta atccgttatg cgaccaaaaa tcggaaatcg ccggctgaaa acagacgcag
    67261 agttggaaaa agtctgagtt tattatctgt ctttgttttt gccatttttt tagtcaattt
    67321 tgcggtcatt attgggacag gcactcgctt tggaacagat ttagcgaagg aagctaagaa
    67381 ggttcatcaa accacccgta cagttcctgc caaacgtggg actatttatg accgaaatgg
    67441 agtcccgatt gctgaggatg caacctccta taatgtctat gcggtcattg atgagaacta
    67501 taagtcagca acgggtaaga ttctttacgt agaaaaaaca caatttaaca aggttgcaga
    67561 ggtctttcat aagtatctgg acatggaaga atcctatgta agagagcaac tctcgcaacc
    67621 taatctcaag caagtttcct ttggagcaaa gggaaatggg attacctatg ccaatatgat
    67681 gtctatcaaa aaagaattgg aagctgcaga ggtcaagggg attgatttta caaccagtcc
    67741 caatcgtagt tacccaaacg gacaatttgc ttctagtttt atcggtctag ctcagctcca
    67801 tgaaaatgaa gatggaagca agagcttgct gggaacctct ggaatggaga gttccttgaa
    67861 cagtattctt gcagggacag acggcattat tacctatgaa aaggatcgtc tgggtaatat
    67921 tgtacccgga acagaacaag tttcccaacg aacgatggac ggtaaggatg tttatacaac
    67981 catttccagc cccctccagt cctttatgga aacccagatg gatgcttttc aagagaaggt
    68041 aaaaggaaag tacatgacag cgactttggt cagtgctaaa acaggggaaa ttctggcaac
    68101 aacgcaacga ccgacctttg atgcagatac aaaagaaggc attacagagg actttgtttg
    68161 gcgtgatatc ctttaccaaa gtaactatga gccaggttcc actatgaaag tgatgatgtt
    68221 ggctgctgct attgataata atacctttcc aggaggagaa gtctttaata gtagtgagtt
    68281 aaaaattgca gatgccacga ttcgagattg ggacgttaat gaaggattga ctggtggcag
    68341 aatgatgact ttttctcaag gttttgcaca ctcaagtaac gttgggatga ctctccttga
    68401 gcaaaagatg ggagatgcta cctggcttga ttatcttaat cgttttaaat ttggagttcc
    68461 gacccgtttc ggtttgacgg atgagtatgc tggtcagctt cctgcggata atattgtcaa
    68521 cattgcgcaa agctcatttg gacaagggat ttcagtgacc cagacacaaa tgattcgtgc
    68581 ctttacagct attgctaatg acggtgtcat gctggagcct aaatttatta gtgccattta
    68641 tgatccaaat gatcaaactg ctcggaaatc tcaaaaagaa attgtgggaa atcctgtttc
    68701 taaagatgca gctagtctaa ctcggactaa catggttttg gtagggacgg atccggttta
    68761 tggaaccatg tataaccaca gcacaggcaa gccaactgta actgttcctg ggcaaaatgt
    68821 agccctcaag tctggtacgg ctcagattgc tgacgagaaa aatggtggtt atctagtcgg
    68881 ggtaaccgac tatattttct cggctgtatc gatgagtccg gctgaaaatc ctgattttat
    68941 cttgtatgtg acggtccaac aacctgaaca ttattcaggt attcagttgg gagaatttgc
    69001 caatcctatc ttggagcggg cttcagctat gaaagactct ctcaatcttc aaacaacagc
    69061 taaagctttg gagcaagtaa gtcaacaaag tccttatcct atgcctagtg tcaaggatat
    69121 ttcacctggt gatttagcag aagaattgcg tcgcaatctt gtacaaccca tcgttgtggg
    69181 aacaggaacg aagattaaaa acagttctgc tgaagaaggg aagaatcttg ccccgaacca
    69241 gcaagtcctt atcttatctg ataaagcaga ggaagttcca gatatgtatg gttggacaaa
    69301 ggagactgct gagacctttg ctaagtggct caatatagaa cttgaatttc aaggttcggg
    69361 ctctactgtg cagaagcaag atgttcgtgc taacacagct atcaaggaca ttaaaaaaat
    69421 tacattaact ttaggagact aatatgttta tttccctcag tgctggaatt gtgacatttt
    69481 tactaacttt agtaggaatt ccggccttta tccaatttta tagaaaggcg caaattacag
    69541 gccagcagat gcatgaggat gtcaaacagc atcaggcaaa agctgggact cctacaatgg
    69601 gaggtttggt tttcttgatt acttctgttt tggttgcttt ctttttcgcc ctatttagta
    69661 gccaattcag caataatgtg ggaatgattt tgttcatctt ggtcttgtat ggcttggtcg
    69721 gatttttaga tgactttctc aaggtctttc gtaaaatcaa tgaggggctt aatcctaagc
    69781 aaaaattagc tcttcagctt ctaggtggag ttatcttcta tcttttctat gagcgcggtg
    69841 gcgatatgct ttctgtcttt ggttatcaag tgcatctagg gattttctat attgtcttcg
    69901 ctcttttctg gctagtcggt ttttcaaacg cagtaaactt gacagacggt gttgacggtt
    69961 tagctagtat ttccgttgtg attagtttgt ctgcctatgg agttattgcc tatgtgcaag
    70021 gtcagatgga tattcttcta gtgattcttg ccatgattgg tggtttgctc ggtttcttca
    70081 tctttaacca taagcctgcc aaggtcttta tgggtgatgt gggaagtttg gccctaggtg
    70141 ggatgctggc agctatctct atggctctcc accaagaatg gactctcttg attatcggaa
    70201 ttgtgtatgt ttttgaaaca acttctgtta tgatgcaagt cagttatttc aaactgacag
    70261 gtggtaaacg tattttccgt atgacgcctg tacatcacca ttttgagctt gggggattgt
    70321 ctggtaaagg aaatccttgg agcgagtgga aggttgactt cttcttttgg ggagtgggac
    70381 ttctagcaag tctcctgacc ctcgcaattt tatatttgat gtaagaatgg caccctgatg
    70441 tttcagggtg tttttgtgtt taaatacaca atgaaaatca aagaacaatc tagaaagcta
    70501 actttaggct gctcaaaaca tagtagtttg aaactagaat agtacacctc tacttct
//
LOCUS       DAVLZS010000004        68873 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLZS010000004 DAVLZS010000000
VERSION     DAVLZS010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.004"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..138
                     /locus_tag="VYO88_000219"
     CDS             <1..138
                     /locus_tag="VYO88_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718395.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
     gene            complement(618..767)
                     /gene="rpmG"
                     /locus_tag="VYO88_000220"
     CDS             complement(618..767)
                     /gene="rpmG"
                     /locus_tag="VYO88_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1718396.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(783..965)
                     /gene="rpmF"
                     /locus_tag="VYO88_000221"
     CDS             complement(783..965)
                     /gene="rpmF"
                     /locus_tag="VYO88_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1718397.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(1117..1317)
                     /locus_tag="VYO88_000222"
     CDS             complement(1117..1317)
                     /locus_tag="VYO88_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1718398.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(1320..2327)
                     /locus_tag="VYO88_000223"
     CDS             complement(1320..2327)
                     /locus_tag="VYO88_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1718399.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            2519..4549
                     /locus_tag="VYO88_000224"
     CDS             2519..4549
                     /locus_tag="VYO88_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1718400.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            4553..4837
                     /locus_tag="VYO88_000225"
     CDS             4553..4837
                     /locus_tag="VYO88_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1718401.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            4850..6196
                     /locus_tag="VYO88_000226"
     CDS             4850..6196
                     /locus_tag="VYO88_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1718402.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            6200..7057
                     /locus_tag="VYO88_000227"
     CDS             6200..7057
                     /locus_tag="VYO88_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1718403.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            7054..7986
                     /locus_tag="VYO88_000228"
     CDS             7054..7986
                     /locus_tag="VYO88_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1718404.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            8219..9922
                     /gene="ilvD"
                     /locus_tag="VYO88_000229"
     CDS             8219..9922
                     /gene="ilvD"
                     /locus_tag="VYO88_000229"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1718405.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(10038..10118)
                     /locus_tag="VYO88_000230"
                     /pseudo
     CDS             complement(10038..10118)
                     /locus_tag="VYO88_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10176..10517)
                     /locus_tag="VYO88_000231"
     CDS             complement(10176..10517)
                     /locus_tag="VYO88_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1718406.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10641..11492
                     /gene="rgg"
                     /locus_tag="VYO88_000232"
     CDS             10641..11492
                     /gene="rgg"
                     /locus_tag="VYO88_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1718407.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSTEY
                     YRKTLDS"
     gene            11683..12930
                     /locus_tag="VYO88_000233"
     CDS             11683..12930
                     /locus_tag="VYO88_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV1718408.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASVFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLDLSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANVFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLDLLFTLFIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            13008..14297
                     /locus_tag="VYO88_000234"
     CDS             13008..14297
                     /locus_tag="VYO88_000234"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1718409.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLEIISKNFSEIFEKLGFYTQ"
     gene            14294..14371
                     /locus_tag="VYO88_000235"
                     /pseudo
     CDS             14294..14371
                     /locus_tag="VYO88_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14638..14952
                     /locus_tag="VYO88_000236"
     CDS             14638..14952
                     /locus_tag="VYO88_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718410.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            14962..15168
                     /locus_tag="VYO88_000237"
     CDS             14962..15168
                     /locus_tag="VYO88_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1718411.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            15168..15365
                     /locus_tag="VYO88_000238"
     CDS             15168..15365
                     /locus_tag="VYO88_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718412.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            15421..16101
                     /locus_tag="VYO88_000239"
     CDS             15421..16101
                     /locus_tag="VYO88_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1718413.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVAIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            16113..16754
                     /locus_tag="VYO88_000240"
     CDS             16113..16754
                     /locus_tag="VYO88_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1718414.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            16772..17002
                     /locus_tag="VYO88_000241"
     CDS             16772..17002
                     /locus_tag="VYO88_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718415.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            17038..17118
                     /locus_tag="VYO88_000242"
                     /pseudo
     CDS             17038..17118
                     /locus_tag="VYO88_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            17242..17325
                     /locus_tag="VYO88_000243"
                     /pseudo
     CDS             17242..17325
                     /locus_tag="VYO88_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
     gene            17444..19207
                     /gene="aspS"
                     /locus_tag="VYO88_000244"
     CDS             17444..19207
                     /gene="aspS"
                     /locus_tag="VYO88_000244"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1718416.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVVAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            19185..20126
                     /locus_tag="VYO88_000245"
     CDS             19185..20126
                     /locus_tag="VYO88_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1718417.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(20130..20321)
                     /locus_tag="VYO88_000246"
     CDS             complement(20130..20321)
                     /locus_tag="VYO88_000246"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718418.1"
                     /translation="MKIKVQTRKLAAGCSKHYFEVVDRTDEVSSKHGFEVVDETDEVS
                     NHIYGKVKLTWFEEIFEEY"
     gene            complement(20463..21449)
                     /locus_tag="VYO88_000247"
     CDS             complement(20463..21449)
                     /locus_tag="VYO88_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1718419.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(21459..22259)
                     /locus_tag="VYO88_000248"
     CDS             complement(21459..22259)
                     /locus_tag="VYO88_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1718420.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(22512..23354)
                     /locus_tag="VYO88_000249"
     CDS             complement(22512..23354)
                     /locus_tag="VYO88_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1718421.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(23356..24648)
                     /locus_tag="VYO88_000250"
     CDS             complement(23356..24648)
                     /locus_tag="VYO88_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1718422.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(24759..26030)
                     /locus_tag="VYO88_000251"
     CDS             complement(24759..26030)
                     /locus_tag="VYO88_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1718423.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            26580..28097
                     /gene="malQ"
                     /locus_tag="VYO88_000252"
     CDS             26580..28097
                     /gene="malQ"
                     /locus_tag="VYO88_000252"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1718424.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28123..30381
                     /gene="glgP"
                     /locus_tag="VYO88_000253"
     CDS             28123..30381
                     /gene="glgP"
                     /locus_tag="VYO88_000253"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1718425.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLRVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(31426..31998)
                     /locus_tag="VYO88_000254"
     CDS             complement(31426..31998)
                     /locus_tag="VYO88_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718426.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(32621..33469)
                     /locus_tag="VYO88_000255"
     CDS             complement(32621..33469)
                     /locus_tag="VYO88_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1718427.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            33621..33899
                     /locus_tag="VYO88_000256"
     CDS             33621..33899
                     /locus_tag="VYO88_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718428.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            33901..35964
                     /locus_tag="VYO88_000257"
     CDS             33901..35964
                     /locus_tag="VYO88_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1718429.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(36042..37298)
                     /locus_tag="VYO88_000258"
     CDS             complement(36042..37298)
                     /locus_tag="VYO88_000258"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1718430.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGGRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            37440..39905
                     /locus_tag="VYO88_000259"
     CDS             37440..39905
                     /locus_tag="VYO88_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1718431.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            39970..40881
                     /locus_tag="VYO88_000260"
     CDS             39970..40881
                     /locus_tag="VYO88_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1718432.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIVLIILPMIFLSIEEAKESR"
     gene            41111..41809
                     /gene="dapD"
                     /locus_tag="VYO88_000261"
     CDS             41111..41809
                     /gene="dapD"
                     /locus_tag="VYO88_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1718433.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            41877..43007
                     /locus_tag="VYO88_000262"
     CDS             41877..43007
                     /locus_tag="VYO88_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1718434.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            43019..43558
                     /locus_tag="VYO88_000263"
     CDS             43019..43558
                     /locus_tag="VYO88_000263"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1718435.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKRVLTPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            43542..44219
                     /locus_tag="VYO88_000264"
     CDS             43542..44219
                     /locus_tag="VYO88_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1718436.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(44286..45185)
                     /gene="galU"
                     /locus_tag="VYO88_000265"
     CDS             complement(44286..45185)
                     /gene="galU"
                     /locus_tag="VYO88_000265"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1718437.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(45207..46223)
                     /locus_tag="VYO88_000266"
     CDS             complement(45207..46223)
                     /locus_tag="VYO88_000266"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1718438.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            46435..46875
                     /locus_tag="VYO88_000267"
     CDS             46435..46875
                     /locus_tag="VYO88_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1718439.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(46998..47414)
                     /locus_tag="VYO88_000268"
     CDS             complement(46998..47414)
                     /locus_tag="VYO88_000268"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1718440.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(47482..48132)
                     /gene="phoU"
                     /locus_tag="VYO88_000269"
     CDS             complement(47482..48132)
                     /gene="phoU"
                     /locus_tag="VYO88_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1718441.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(48147..48899)
                     /gene="pstB"
                     /locus_tag="VYO88_000270"
     CDS             complement(48147..48899)
                     /gene="pstB"
                     /locus_tag="VYO88_000270"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1718442.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(48901..49716)
                     /gene="pstA"
                     /locus_tag="VYO88_000271"
     CDS             complement(48901..49716)
                     /gene="pstA"
                     /locus_tag="VYO88_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1718443.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(49709..50572)
                     /gene="pstC"
                     /locus_tag="VYO88_000272"
     CDS             complement(49709..50572)
                     /gene="pstC"
                     /locus_tag="VYO88_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1718444.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(50690..51565)
                     /locus_tag="VYO88_000273"
     CDS             complement(50690..51565)
                     /locus_tag="VYO88_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1718445.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(51732..53063)
                     /locus_tag="VYO88_000274"
     CDS             complement(51732..53063)
                     /locus_tag="VYO88_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1718446.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(53064..53771)
                     /locus_tag="VYO88_000275"
     CDS             complement(53064..53771)
                     /locus_tag="VYO88_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1718447.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(53855..54331)
                     /locus_tag="VYO88_000276"
     CDS             complement(53855..54331)
                     /locus_tag="VYO88_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1718448.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEVVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            54338..54884
                     /locus_tag="VYO88_000277"
                     /pseudo
     CDS             54338..54884
                     /locus_tag="VYO88_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55199..56890)
                     /locus_tag="VYO88_000278"
     CDS             complement(55199..56890)
                     /locus_tag="VYO88_000278"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1718449.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            57026..57472
                     /gene="argR"
                     /locus_tag="VYO88_000279"
     CDS             57026..57472
                     /gene="argR"
                     /locus_tag="VYO88_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1718450.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            57523..60057
                     /gene="mutS"
                     /locus_tag="VYO88_000280"
     CDS             57523..60057
                     /gene="mutS"
                     /locus_tag="VYO88_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1718451.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDLYNMTPMQVMNVLVELKQKL"
     gene            60204..61898
                     /gene="patA"
                     /locus_tag="VYO88_000281"
     CDS             60204..61898
                     /gene="patA"
                     /locus_tag="VYO88_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1718452.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(62228..62491)
                     /locus_tag="VYO88_000282"
                     /pseudo
     CDS             complement(62228..62491)
                     /locus_tag="VYO88_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            62689..64455
                     /gene="patB"
                     /locus_tag="VYO88_000283"
     CDS             62689..64455
                     /gene="patB"
                     /locus_tag="VYO88_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1718453.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEILI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            64594..65283
                     /locus_tag="VYO88_000284"
     CDS             64594..65283
                     /locus_tag="VYO88_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1718454.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            65287..65466
                     /locus_tag="VYO88_000285"
     CDS             65287..65466
                     /locus_tag="VYO88_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718455.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            65453..66802
                     /locus_tag="VYO88_000286"
     CDS             65453..66802
                     /locus_tag="VYO88_000286"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1718456.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            66927..68387
                     /locus_tag="VYO88_000287"
     CDS             66927..68387
                     /locus_tag="VYO88_000287"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1718457.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREEFIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            68401..68835
                     /locus_tag="VYO88_000288"
     CDS             68401..68835
                     /locus_tag="VYO88_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1718458.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGKERASKFNER"
BASE COUNT        20232 a        12775 c        14912 g        20954 t
ORIGIN      
        1 gaatcaggtt caatggctac tggttggttt acagtttctg gtaaatggta ctatacctat
       61 aattcaggag atttattagt aaacacgact acacccgatg gctatcgagt caatgctaac
      121 ggtgagtggg taggataggt atccattagc taaatctaat cattctgaac taaaaaatct
      181 tcttacatat gtaggaagat tttttggatt ctcaaaacta gtttaaaaga ctacgctatt
      241 taaaccaatt ttaagaatgg atatataagg atattcagaa atctagttgg tcaacttttg
      301 tattttgaat ataccttaga tggtgacgat gtcttggtat atctggtact cacttacata
      361 ttctaactta ttttaactaa gatgcaactg tagttggtga atttgctaca aatagtgtag
      421 aggcgttatt tgaaaaatat acaaaaaagg aaccccaact tacatttgag tttctcttac
      481 ttttaatcgt ccgaatccgt attcttattt caaaaaatgt agtcattcga atgatttctc
      541 ttgcaatata gtgaaattaa caaaaagaaa aaacgctgat caagcgtttt tcttctgtat
      601 tgattcgtat tgaatgctta cttcacttct gtaaacacaa cgtgtttgcg aagttttggt
      661 gagtatttct tcaattgaag gcggtctgga gtgttacgtt tgtttttaga agtaaggtac
      721 aagcgttcac cagattcttt gtgttcaagt gtaatattta cgcgcatggt atctcccttc
      781 tattattcag ctgatgcagc tttagcgatt ttacgtcctt tgtagtatcc tttaagtgat
      841 acacggtgag aacgtgagta atctccagta gtttcgtcaa agtttacaga tggagctgtt
      901 actttgtagt gtgtacgacg tttgtttttc ttcgcttttg aagtgcgacg tgcaggtact
      961 gccattttga tttctccttt aggtatttat attcgattca atctactgat tttcatcaac
     1021 catactagga taacacattt tttttgtaaa gtaaagttac ttgacaaaaa aagatgaaaa
     1081 aattctccta tccgacacgg cagacaggag aaggtgttaa atatcaatct caaatggttc
     1141 gtcaatggtt tctgatacgt attttccgtc tttcttccgt tgcttgacac actctgtgag
     1201 gagatattcg atttggccat tgactgaacg aaagtcgtct tctgcccatg atgcgagtgc
     1261 agcgtataac tttgttgaga gtcgaagggg gatctgcttt tttttagctt cagccatctt
     1321 tagtaaagac ttcctgtgtt gacaattggt tgtgcatcat gattgccaca aagaacgaca
     1381 aggagatttg aaaccatggc agcttttcgt tcttcgtcaa gttctaccaa ttccccttca
     1441 ttgagccgtt ctagtgccat ttcaaccatt cctacagcac catctacaat catcttacgt
     1501 gcatcaataa tggcagatgc ttgttggcgt tgaagcataa cggcagcaat ttctggagca
     1561 taagctaggt aagtgatacg tgcttcaagg atttccaagc cagcatcctc aacacgactt
     1621 tggatttctt cacgaatacg gttagcaaca atttcgctag agccacggag actaccttca
     1681 tctgcttgcc catcacccgt agtatccaca ttaggagaca catcgtaagg atagatgcgg
     1741 acaatattac ggagggcgct atcacattgc aatgaaagat attctttgta gttatcaacg
     1801 ttgaagactg ccttagcggt atcgacaact ctccaagtta ccgcgatacc gatttctaca
     1861 gggtttccta agcaatcatt gattttttga cgagaattgc tcaaggtcat gactttgagg
     1921 gaaatgtgtt tcttgccaat ttcaagattt acatcattgt catttgatga tttagctcct
     1981 aaaaaaggag attttgtgct aacatcacca ctttgtccaa gtcgagtgtg gtttgcaggg
     2041 ttgactgcta cgctgaaggg attgacaaag taaaaaccag gttctttgat ggtacctgta
     2101 taattaccaa agagtgtcag aaccagagct tcctgaggtt tgacaacttt taaaccagca
     2161 tgagctagac ctgcaattac gattagtaaa ggtccgataa taattccaaa aatgttttcc
     2221 gaaccaaccc ccattataaa tataaagata ccaagtacga ttgtcaactc aatgagaatc
     2281 aatgcgaata caccatttgg ttttgaattg attagttttt cagtcataag aatgacctcc
     2341 tgttatttga tatctaaatg atatcacttt aatttataaa gtcaatagaa agttgaaaaa
     2401 taatcactaa aaactttcag cccaataatt tcttttaaaa ggtgagatta tattgtgctc
     2461 aaatactctt ttattcttat aatttttaca ctataattgt agttagaaag gaagagaaat
     2521 gtttgattat agagcactag ttattttgat gactttgatg gatcattgtg agctatcatt
     2581 atatgaatta tctgttaagg tgagcttacc tataaaggaa gtcaaagaag gaatagatta
     2641 tttagtgcct tatctagcta ataaagggat agtgctggat aaaaaacaag gtcgctatag
     2701 tttatcaaat cgtacgaagc agtctttgac agatattatt aagtcggatg aattggtttt
     2761 accaaagtcg actcgcttag ctttaatcta tctttacact ttttgccgat tagattttat
     2821 atcgaataat cattaccaag actttttgaa agtaagtaag aatacaacct tatctgatat
     2881 tcaatcatta agaaagatta tgttagataa tgatttggag ctagggtaca gtagagcaaa
     2941 aggttatact ttacacggtt cagagtggaa taagcaccgc ttagcttttc aaatggttag
     3001 tgagttgctg gaatcctcca tagggatttg gggtttggat tatgttttat ccagttgggg
     3061 gtattcatta acttatgatt tgattgatca ggtagttaaa gattattatg agaagctaca
     3121 gctagtacct attgttaatc aattaaaagt ttaccttttc ggtttagtat tcattctgtg
     3181 taggtatcaa agggatgttg aaagagtatg tctttcagag acattagtat ctcctgttat
     3241 tcaagatata accactattt tattggatac agtggttgat ttgggaatta tagatacggt
     3301 gttttctgag gatgattatc gctatatcac cgttttatta tcaagttgct ttgaaggtga
     3361 agtagatgtt gctccggttt actttaatca attaacagag gctattataa gtagaatgga
     3421 agatatttct ttgttacatt ttaaacaaag ggaaggattg agagaaaatc ttcgccgcca
     3481 ccttataccg gcttactata gattaaagtt cggcctacct agttcaaatg aatatgtatt
     3541 gcatgttaaa gaacattatc ctgatttatt tgaattagtc aaagattctt tgatgccctt
     3601 gatggacgct attgacaatc ccatacctga tagtgaaaca gcatattttg ttatccattt
     3661 cggaggttat ttaaagaaag cagatacttt gcctcaaaaa tggtataaag cagcaatcat
     3721 ttgtcctaat ggtgttagtt cttcattgat gttaaaagag aatctattag cattatttcc
     3781 tcaaattgag tttataggaa cctcaaagat tgatgattta caggtgaaag ctagtagtga
     3841 ctatgatatg gttttttcta ccataaaggt ggagacagaa aagccaaatt atctagtttc
     3901 ggttatgatg actgaagagc aagcaataca actagtagaa ctagtgttaa aagattttcc
     3961 gaatttagag tatggagatt ttgagattga acaaatcctg aatattgtca aaagatatgg
     4021 aattattaca caagaattgg aattaagatt ggcgttaaag aattatcttt atcaaaaaaa
     4081 tgatagaaag gaaattgtac cagtgctaga acaacttatt accaaagaaa cctatcaggt
     4141 tagttcgcaa aaattaggat ggaaggaggc gattcgttta gcagctaaac cgcttttgga
     4201 tcaagataag ataactgaga actaccctga ggcaatgatt caaaaagtag aagagtttgg
     4261 accttttatt aatttaggga agggagtagc aattcctcac gctcggccag atgaaggtgt
     4321 gaatgaaata ggaatgtcaa tgttagtttt ggaagaaccg atttatttat tggataatcc
     4381 agaacaagag gtaagattgt tgatttgtat tgcagccatt gataatgaga gtcatttaaa
     4441 ggctttgtca catttaacaa caattttaag agataaaaat catgttcaaa ctttaatatc
     4501 atcaaaaaac tataatgata ttaaaatgat aattaaacag gaggattaga taatgttaaa
     4561 aattggtaca gcttgtggtt caggattagg ttcaagtttt atggtacaga tgaatattga
     4621 atctgtattg agtgatttga atgtttcgga tgtagaagtt gaacattatg atttaggtgg
     4681 agcagatcca aatgcagctg atatttggat tgttggtcgt gatctagctg attcagctag
     4741 tcatcttgga gatgttcgta tcttaaatag tattattgat atggatgaac tacgagaatt
     4801 aattactaaa ctttgtgaag aaaaaggact tatataggag gctagcgtca tgatgaagtt
     4861 catattggat attgttagta caccagctat tttagtagct ttaattgcaa ttttaggatt
     4921 agttcttcag aagaagaaat tacctgatat tattaaaggt ggaattaaga cctttgttgg
     4981 tttcttagtt gtatctggtg gtgcaggaat tgtacaaaat tctttaaatc catttggtac
     5041 catgtttgag catgcttttc atttatctgg cgttgtgccg aataatgaag caattgtagc
     5101 tgtagcttta acaacatatg gctcagctac tgcaatgatt atgtttgcag gaatggtgtt
     5161 caatatctta atcgctcgtt ttactcgatt taaatatatt tttttaacag ggcaccacac
     5221 tctatatatg gcatgtatga ttgcggtcat tttatcagtt gctggcttta ctagcttgcc
     5281 tctcatctta ctaggaggat tagcactcgg tattattatg agtatttccc cagcatttgt
     5341 gcaaaaatat atggttcaat taactggaaa tgacaaggtg gctttaggtc atttcagttc
     5401 tttgggatat tggttgagtg gttttactgg tagccttatc ggtgacaaat caaaatcaac
     5461 agaggacatt aaatttccaa agagtttagc ttttttacgt gatagtactg ttagtatcac
     5521 tttatctatg gcagttattt acattattgt agctatcttt gcagggtcag aatatataga
     5581 aaaagaaatc agtagtggta caagtggtct agtttatgct ttacaattag caggtcaatt
     5641 tgcagcaggg gtatttgtta ttttagcagg tgttcgcctt attttgggcg aaattgttcc
     5701 agcctttaaa ggtatttcag agcgtcttgt acctaattca aaacctgctt tggattgtcc
     5761 gattgtttat acttatgcac ctaatgcagt tctaattgga tttatctcta gttttattgg
     5821 tggtttagta agtatggcaa ttatgattgc ttcaggaacg gttgttatct taccaggcgt
     5881 tgtgcctcat ttcttctgtg gagcgactgc aggtgttatt gggaatgcat ctggtggtgt
     5941 tcgtggagcc actattggag catttttaca aggtatttta atcagttttc tcccagtctt
     6001 tttaatgcca gttttgggag gactcggttt ccaaggatca actttctcag atgcagattt
     6061 tggtctatca ggaattattt taggaatgtt aaatcaattt ggctcacaag caggcattgt
     6121 gattggtctt gttcttattt tagcagttat gtttggagta tcctttatta aaaagccatc
     6181 tgcaaaggag gaataaggga tgattttaag taaaaataga gaagatgagt taagaaaatt
     6241 tgcgactaac atccgattaa atactcttag aacattgaat catcttggat tcggacatta
     6301 cggaggaagt ctgtctatcg tagaagtttt agcagtgctt tatggtgaaa taatgccaat
     6361 gactccagaa atatttgcag cacgagatag agattatttc atattatcaa aaggtcatgg
     6421 aggaccagct ctatacagta cactctattt gaatggtttc tttgacaaag aattcttata
     6481 ttctttaaat acaaatggaa ccaaattacc gtctcatcct gatagaaatc taacgccagg
     6541 catagatatg acaacgggct ctttaggaca aggaattagt gttgcaactg gacttgcata
     6601 tggtcagaga ataagaaaga gtccctttta tacttatgct attgttggag atggtgagtt
     6661 aaatgaggga caatgttggg aggctataca gtttgcttct catcaacagt tatccaactt
     6721 aattgtattt gttgatgata acaaaaaaca attagatggt tttacaaagg atatttgtaa
     6781 tccaggtgat ttcgtagaaa aattttcagc atttggattt gaatccatta gggtcaaggg
     6841 ttcagatatt agagaaattt atgaagggat tgtccaatta aaacagtcaa ataattcatc
     6901 acctaagtgc attgtattag atactattaa aggtcaaggg gttcaagagc tggaagaaat
     6961 gaaatccaac catcatcttc gccctactgt agaggagaga caaatgttaa cttcagttgt
     7021 agaaagatta agtcaggaat tggaggaaac agaatgatga gaagcacgaa agaattacgg
     7081 catgtatata gagacttcct tttagaggct aatcaaagtt attctgatat agtagtctta
     7141 gaagctgatt tgtcaagttc gatggctact cataatcttg aaaaggactt tggagaccgt
     7201 tatgtgaatg ttgggattat ggaagcagaa atggtcggcc ttgcagcagg cttgtctatt
     7261 caggggttta gaccttatct tcatacattt ggtccttttg cttcacgaag agtatttgat
     7321 caattattta tttctcttgg atacgcacaa ttggatgcca ctgtgattgg atcagatgca
     7381 ggagtaactg cagaaatgaa tggtgggaca catatgccat ttgaagaaat tggattgtta
     7441 cgtttaattc ctaaatcgat catttttgaa gcaactgatg atatccaatt tcgtgaaata
     7501 ttgaaccaga cattagactt aaaaggacta aaatatattc gaacaattag aaaagctcca
     7561 gttcctgtgt atcaaggtgg agaagatttt tctaaaggct acattgagtt aaggcatggt
     7621 gaagatcttg taatcgttgc ttctggtata atggttgctc caagtattcg agttgcagat
     7681 gaactgtcta aattaggtta ttcagtaagt gtgatagatt tatttagaat caaaccgata
     7741 ccagaacaga taaaaacaat gttaagtgga aaaactatat ttactgtaga aaaccacaat
     7801 cagataggtg gaattggcag ttctttatgt gaattattct ctgatgatgg aatgacaaaa
     7861 attcatcgga tgggtgttca agaaagattc ggtcaagtag ggaaaatgga ttatcttctt
     7921 aatgagtatg gtttgagtga atcgaatata aaagagaagg ttctagaaat ttataatgca
     7981 agatagatgt taaatacact tatctgaaag aatttctgta aaaattacag tacgttattt
     8041 aaagaaagcg gattaaaaag catattctgg tcatcagaaa gtgcactaat ccgctttgtt
     8101 gtttttaatt ttaaatattt cacatgcgta tagaattttc tgaaaattca agaattttat
     8161 tctgttcatt gcctttaaat tgtgctataa tagtaaaaac tgaaatggga gggataagat
     8221 gactgaatta gataaacgtc accgcagtag catctatgac agcatggtta aatcacctaa
     8281 ccgtgctatg cttcgtgcga ctggtatgac agataaggac tttgaaacat cgattgtggg
     8341 agtgatttcg acttgggcgg aaaatacacc atgtaacatt cacttgcatg atttcgggaa
     8401 actggctaaa gaaggtgtca aatctgcagg cgcttggcct gtacagtttg gaaccattac
     8461 cgtagcggac gggattgcta tgggaacgcc tggtatgcgt ttctctctaa catctcgtga
     8521 catcatcgcg gactccatcg aggcggctat gagtggtcac aacgtggatg ccttcgtcgc
     8581 tatcggtggc tgtgacaaga acatgcctgg atctatgatt gctattgcta atatggatat
     8641 cccagctatt ttcgcctatg gtggaactat tgcaccggga aatcttgatg gtaaagatat
     8701 cgacttggtt tctgtctttg aaggtatcgg aaaatggaac cacggtgata tgacagctga
     8761 ggacgtgaaa cgtcttgaat gtaatgcctg ccctggccct ggtggttgtg gtggtatgta
     8821 tactgctaat accatggcaa ctgctatcga agttctaggg atgagtttgc cagggtcatc
     8881 ctctcaccca gctgaatcag ctgataagaa agaagatatc gaagcagcag gacgtgctgt
     8941 tgttaagatg ttggagcttg gtctcaaacc atcagatatc ttgactcgtg aagcctttga
     9001 agatgctatc actgtaacga tggctctcgg tggttctaca aacgccactc ttcacttgct
     9061 cgccattgcc catgccgcaa atgttgactt gtcacttgag gacttcaata cgattcaaga
     9121 acgtgtgcct cacttggccg acttgaaacc atctggtcag tatgtcttcc aagacctcta
     9181 cgaagtcggt ggtgtccctg cggttatgaa gtacttgttg gcaaatggtt tccttcacgg
     9241 agatcgcatc acatgtactg gtaagactgt agctgaaaac ttggctgact ttgcagactt
     9301 gactccaggc caaaaagtta tcatgccact tgaaaatcca aaacgtgcgg atggtccgct
     9361 tatcatcttg aacgggaacc ttgctcctga cggtgcagtt gccaaggtat caggtgttaa
     9421 agtgcgtcgt cacgttgggc cagctaaggt ctttgactca gaagaagatg cgattcaggc
     9481 cgttctgaca gatgaaatcg ttgatggcga tgtagtcgtt gttcgttttg ttggacctaa
     9541 aggtggtcct ggtatgcctg agatgctgtc actttcttca atgattgttg gtaaaggtca
     9601 gggagataag gtggccctct tgacggacgg acgtttctct ggtggtactt atggtctggt
     9661 tgttggacat atcgctcctg aagctcagga tggtggacca attgcctatc tccgtaccgg
     9721 cgatatcgtt acggttgacc aagataccaa agaaatttcc atggccgtat ccgaagaaga
     9781 acttgaaaaa cgcaaggcag aaacaacctt gccaccactt tacagccgtg gtgtcctcgg
     9841 taaatatgcc catatcgtat catctgcttc acgcggagcc gtgacagact tctggaatat
     9901 ggacaagtca ggtaaaaaat aaactcatac tcgaaaatct cttcaaatca cgtcaacgtc
     9961 gccttgccgt aggtatggtt actgacttcg tcagttctat ctacaacctc aaaacagtgt
    10021 tttgagctga cttcgtcagt tctatccata acttcaaaac agtgttttga gcaacctgcg
    10081 gctagttttc tagtttgccc tttgattttc attgagtatc aaaaagcaag ccattttcgg
    10141 cttgcttttt tcatctttaa aagtgattgg cctgcttaac gaggtggtag tccaagggca
    10201 atacggccat agcgactgat tcgtgtgatt ttccaagcag gcgaccaggt aacttcaacc
    10261 ttgatatctt tgataccctc gatttgtttc agacctgcca cgatttcaat aggcaggctt
    10321 tcggcgcaat cacaggcagt atcggtgaag gtcatgacaa tcttgcagag ccccgtttca
    10381 tccagattga tttcataaat cagacctaga ttgtaaacat ccaattccac atctgtatca
    10441 aaaactttct ctagtttttc gataatttgg tcttgcaagg ccaaagcacg gtcattgatt
    10501 ttgatatcgt ctctcatagc agtccctcca cgtgataaat atcctctatt ttctcataat
    10561 tctgacaatt tggcaagttt ttgatgaatt ttctgaaaaa tatgataaaa tgaagaaaat
    10621 acggaatcaa ggggaagtct atggagcaga ttggaaaagt ctttagacaa ttacgagaat
    10681 caagaaatat ctcactgaga caagcaaccg gaggacaatt ttcgccgtct atgttgtccc
    10741 gttttgaaac aggtcagagt gagctttcgg tggaaaagtt tctatttgct ctggaaaata
    10801 tatctgccag tgtggaggag atcctctttc tggcgagagg tttccagtat gatacagatt
    10861 ctgagttgag aaaagaaatt acagatgtct tggaaccaaa gaatatagca cctcttgagg
    10921 acttatatcg cagggagtat caaaagcatg cccattctca caacaaacag aaacatattc
    10981 taaatgccat tattatcaag tcttatatga agagcataga tgaaagggta gagttaacag
    11041 cagaggaagg aaaagtcctt catgattatt tgttttctac cgagatctgg ggaatctatg
    11101 aactcaattt attttcagtc agttctccat ttttatctgt ttctcttttt actagatatg
    11161 tacgagaaat ggtacgtaaa tctgattttc taatggaaat gtctggcaat cgaaaccttt
    11221 ttcatactat actattgaat ggctttttag ctagtattga gtgtgaagaa tttaccaatg
    11281 cctattattt taaacgtgtt atcgaagagc atttctacaa ggaaaatgag acctatttcc
    11341 gaattgttta tctgtgggca gaaggtctcc ttgatagcaa gcaaggtaga gtcaaggaag
    11401 gtcagaaaaa gatggaggat gctgtccgta tttttgagat gcttggctgt aataaatcta
    11461 ccgaatacta tagaaaaact ctcgattctt gaatatctgc aaaccaagaa aaaatttgaa
    11521 gcgatagaac tgttgccctc tctcaggtca ttacaaaagt tctatcgttt ttttgctcat
    11581 tttgtttgtt gcatatattc aaaagaatcg tttcgcaaat tcataagtgc tatactaaag
    11641 ctattcttga tgtagaactt agaacaagga gggagattat ctatgaaact attgtttaga
    11701 aatccagctt atagaatttt gactttatca cgcttcttca atgcttttgg tgcttcggtt
    11761 ttcaacctgg tctttatcgt ctatgcatcg accttgtcac aagcatcttt tgctgttgct
    11821 atggcgaata ttgtcatgat tcttccgacc ttctttacag tttttgcagg gattcgggca
    11881 gattacacga gggacaaggt caaatggatg gtctatagcg gtttgtttca ggcggttcta
    11941 ttttttctag cagccctagt tgttcagcaa gctagtctct ttgccttttc tagcctgtgt
    12001 ttgatcaatg tcattagtga tatcatcagt gattttgcag gtggcctgcg tatgcctctt
    12061 attaaggaaa aagtagctga agatgatttg atggaggctt attctttttc acagttcatc
    12121 acctatattt cagctattgg tggtcaagct ttcggagtct ggctcttaga tctatcggtc
    12181 aacaattttt ctctcgttgc gggaatcaat gcctgctttt tcctagtatc agccactatc
    12241 ctctttttag gaaaaagcaa attgagcctg tcaatgtcat ctgctgatgg tgaaaactta
    12301 aaaaatgaga agctttctat caaagaccag ttcctaacaa tttaccgaaa tttacgtctc
    12361 gtttttctta aaagtggaca gaaaaacttt ggttttatgc tctttgctgt cttgcttatt
    12421 aattccttgg gtggcgcttt gggtggaatt tataatatct tctttttgag ccattctctc
    12481 ttgaattttt cttatacaga ggcactattt atcaatcaat tctgtgtttt agtagcaatc
    12541 atcatcagta gccttacggg caatgattat tttgggaagc agtccttgcc tagattgatg
    12601 atgtgggcga ccgtaggact tagtctagtt ggtttggcta acgtattcaa tcaagtcgtg
    12661 cttggtttgc tatttctctt ctttactctg tatgtgtctg gtaaagttca accaaagatt
    12721 agtgccatgc tcatgaaaaa tctagctcca gaggttctag ctcgtactag taatttttta
    12781 gatctattgt ttaccttatt catacctgtg ggaacagctt gtttttcact agtagccgta
    12841 tggaatatac agttgacttg gatgctattt gttggtcttt ccttgctagc tatttttttg
    12901 acaattctta atctcaaaaa tgatatctaa atcctaattt ttttcttact gttttaatcc
    12961 ctctatttat ggtaaaataa gactattaag tttaaagagg attccctatg aaattacaaa
    13021 aaccaaaagg aacgcaggat attttacctg ctgagtctgc taagtggcag tacgttgagg
    13081 gctttgcccg tgagattttc aagcgctata actatgcaga agtgcgcacg cctatttttg
    13141 agcattacga ggttatcagc cgctctgtcg gagatacaac ggatatcgta accaaggaaa
    13201 tgtacgattt ttatgacaag ggtgaccgtc atattaccct ccgtccagaa ggaactgcgc
    13261 ccgttgtccg ttcctatgtg gaaaataaac tcttcgcccc agaagtgcaa aagccaagca
    13321 agttctacta tatgggacct atgttccgtt atgagcgtcc acaggcaggg cgcttgcgcc
    13381 aattccacca gattggtgtt gagtgttttg gctctagcaa tccagctacc gatgtggaaa
    13441 caatcgttat ggcagcccat tttttgaagg aaatcggtat tcaaggtgtc aaattgcacc
    13501 tcaacactct tggaaatcct gagagccgtg cagcctaccg ccaagccttg attgactatt
    13561 tgacaccgct caaggagacc ttgtctaagg atagccaacg tcgcttggag gaaaatcctc
    13621 ttcgtgtctt ggactctaag gaaaaagaag acaaggtggc agtagagaat gcgccgtcta
    13681 tcttggactt tcttgatgaa gaaagccaag ctcattttga tgctgtgcgt cagatgttgg
    13741 aaaatcttgg agtagattac atcatcgata ccaatatggt gcgtggtctg gactactaca
    13801 accacaccat tttcgagttt atcacagaga ttgagggcaa tgacttgaca gtctgtgcgg
    13861 gtggtcgcta cgatggtttg gttgcttact ttggaggccc tgaaactgct ggatttggtt
    13921 ttgggcttgg tgtagagcgt ctgcttctca tccttgaaaa acaaggcgtg gccctcccta
    13981 tcgaaaatgc cctagatgtc tatatcgcag tcttgggtga tggagcaaat gtcaaagctc
    14041 tagaactagt ccaagctctt cgccaacaag gtttcaaagc agagcgtgat tacctcaacc
    14101 gtaagctcaa agctcagttc aagtcagccg atgtctttgt ggctaagacc ctcatcaccc
    14161 taggagagag tgaagtcgaa agcggacaag tgacggtcaa gaacaatcaa actcgagaag
    14221 aagtgcaagt gtcacttgag ataatcagca aaaatttctc agaaatcttt gaaaaactag
    14281 gattttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa
    14341 acagtgtttt gaagttatgg atagaactga tgaagtcagc tcaaaacact gttttgaggt
    14401 tgtggataga actgacgaag tcagtaacca tacctacggc aaggtgaagc tgacgtggtt
    14461 tgaagagatt ttagaagagt attaatgata gataaagtgg tcaggaactt actcctgacc
    14521 tttttctttt gcaaaatgac aaaaatcata aactttttga caactatact tgtcaaaaag
    14581 aaaaagatat gttacaatga attcaagtta agaaatagaa agcagaaagg agttataatg
    14641 tgggtattag gatttatact atttatgatt ttcttttatt ctaataattc taaaaaaatc
    14701 aagaaactag agaataaaat caaaaaactt gagcgaaaag agaaaggaaa cgcagaaatg
    14761 tcgagattat tacaagaaat gattggaaag gaaccaatta taacgggagt gtatattggg
    14821 ccagataact gggaagttgt ggatgttgat gaggaatggg tcaaactacg tagtgttgat
    14881 aatacgggaa aagaaaaatt caagttgcaa cgtattgaag atatccaaac cgttgaattt
    14941 gacggagagt aggtgtgtaa cgtgcaacta aaaaatcgtc taaaagagct tcgagctcgc
    15001 gatggtctca atcaaaccga cctagccaaa ctggcagggg tttccagaca gaccattagc
    15061 ctactagaac gggatgagta caccccatcc attatcattg ccctgaaaat atctcaaatt
    15121 ttcaacgaaa cagtcgaatc ggtatttcgt ttggaggagg acgagtgatg aacaagtata
    15181 aagtgattta ttatgtagtg gtcatagctt tattagtcag cgtatttcta ctgattggga
    15241 tggacctaag ctggtttaat ccctatcaaa gcgaccaatt tgtttgggtc tactttgctc
    15301 tcatcccagt aactgaatgg attgaaaaga aatccaaaaa tctagcaagt gaaaaaggag
    15361 aatgaatatg aaaaagaaac gtagattgtt atttttgatg tctattgtct tgggggggtc
    15421 ttgggcatgt ttgtagggat gtttaaggca cgtgtcgaat cccacgaaat tattttagat
    15481 gtaaaagcct tgatgccatg gatatcagct atttgtttac tgataggttt cattagtatg
    15541 tttttgactt tcaatttctt aaagaaaagc agaaaatttc attccttgta tcaagaggaa
    15601 atggatgacg atctgaatga aacctattat gtgcaaatgt atcggaatct tgagtttgga
    15661 accattgctt ttaatattac aggtgtagcg attccattgg ctatttttat ttcattaagt
    15721 gaggtgatta tattgcatac aaaccctcaa acatttttcc tttctttctt actctttgtg
    15781 gtattcttag tcgctcaaaa atctcttttt aaaaccattg cgattgttcg tcagtttgat
    15841 ttggaatttt tcgctacacc aaaggatgtc ttgaactata taaattctta tgatgaaggg
    15901 gagcgtcagg ctaatttgga acagagtttt cgaattttat tccaattaca ccaatatgtc
    15961 ttaccagcct tatatatttt tcttattatc ctttctttct tgacaggaga gattcagtta
    16021 ctagctttct tgcttgtagg agccatccat gtttatatca atgtgatgca gttacctatg
    16081 gtaaaacgtt atttcaaata aaggagttat ctatgaaatt acttaaaaac cttggctggt
    16141 ttcttctagc ccttctatcc tttttcttta tctatggctt tattcagggg ctcgcgactg
    16201 cgtcgcttgc tttaggcgct tcaccctatg ctgttactct actctatgtg gtcttggctg
    16261 gagtatatgt gtacggcatt tacaaatggt atcagaaagc tcctgtttat attgagaaga
    16321 gcggctttaa ccgatttatt tggcttcctg ccttggtttg gttcttatct ctggtcgttc
    16381 aattcttctt gccagatgat ccttcagtaa atcagcaaat agcgacagac ttgaccttgt
    16441 ctcaaccact tttctcattc tttgctgtgg ttatttttgc tcctttgacg gaagagattg
    16501 tttttagagg gatgttagca cgctatctct ttcctaagca ggacaatagt aaacgaaccc
    16561 tgatttttct tctggtatct agtcttctat ttgccttgat tcattttcca ggtgatgtgc
    16621 aacaattttt tgtctatttt agccttggtt ttagtttggg tttggcttac attagcagaa
    16681 aaggtctggt ctacagtatt tctcttcacg ctttgaataa tttagtcggc tttttgatga
    16741 ttctcatgct ataatagagt caggaggtca catgaaacga gtaattttat tagcagtgat
    16801 tcaggcagtc gttctatttt tcatcattgg agcgctagct tatgccttca aaggcgattt
    16861 cttctataac tatctagcag ttgtctttgc tcctattgca ggtgtactgc gttttgggac
    16921 ggcttacata acggaaattg tcttgcctcg aaaggcagcc gaaatcgctg aaaagcgtaa
    16981 agcaggcaaa aattcaaaat aaaagagtcc ggtgaagttc atcggatttt tgtattatac
    17041 tcaatgaaaa tcaaagagca aactaggaag ctaaccgcag gttgctcaaa acactgtttt
    17101 gaggttgtgg atgaaactga cgaagtcagc tcaaaacatg gttttgaggt tgtagatgaa
    17161 actgacgaag tcagctcaaa acatggtttt gaggttgtag atgaaactga cgaagtcagc
    17221 tcaaaacatg gttttgaggt tgtagatgaa actgacgaag tcagtaacca tacctacggt
    17281 aaggcgacgc tgacgtggtt tgaagagatt ttcgaagagt attagcgcta atttttaggg
    17341 ctttcacctg acttttaaag actggcaaac ttttctgatg attttcatga agagcctgcg
    17401 cttttatggt aaaatagtaa cagaataaaa gaggagagaa ataatgaaac gtagtatgta
    17461 tgctggtcgt gttcgtgagg aacacatcgg acaagaaata accttgaaag gatgggttgg
    17521 gcgtcgtcgt gaccttggtg gtttgatctt tatcgatctt cgtgaccgtg aaggaatcat
    17581 gcagttggtt atcaaccctg aaaaagtatc tgcagaggtt atggcaacag ctgaaagcct
    17641 tcgtagcgaa tttgttattg aggtgactgg tcaggtcgtt gcgcgtgagc aagccaatga
    17701 taagttgcca actggtgcgg ttgagttaaa cgtgacagct cttattgtgc ttaacacagc
    17761 taagacaaca ccatttgaga ttaaggatgg cattgaggca aatgacgata cacgtttgcg
    17821 ttaccgttac cttgaccttc gtcgtccaga aatgttggaa aatcttaaac ttcgtgccaa
    17881 ggtgacccac tctatccgca actacttgga tgagttggag tttatcgacg tggagacacc
    17941 attcctttct aagtcaacgc ctgaaggggc gcgtgattat ttagtgccgt ctcgtgttaa
    18001 taaggggcat ttttacgctc ttcctcaaag tccacaaatc acgaaacagc tcttgatgaa
    18061 tgctggtttt gaccgttact accaaatcgt taaatgtttc cgtgacgagg acttgcgtgg
    18121 agaccgccag cctgaattta ctcaggtcga cttggaaacg tccttcctta ctgagcaaga
    18181 aatccaagat attacagaag gcttgatcgc gcgcgtgatg aaggaaacaa aaggcatcga
    18241 agtaacgcta ccgttccctc gtatgaaata cgatgatgct atggctcttt acggttctga
    18301 caagccagat actcgttttg acatgttgct tcaggacttg acagaagtgg tcaaaggtgt
    18361 agactttaaa gtcttttcag aagcacttgc tgtaaaagcg attgtggtca aaggagctgc
    18421 ggacaactat tcacgtaaag acatcgacaa gatgacggaa gtagccaaac agtatggtgc
    18481 caaaggtctt gcttgggtca aggtggttga tggagaatta aacggaccag ttgccaagtt
    18541 cttgactggt atccaagaag aattgacaac agcgcttgct cttgaagata aggacttggt
    18601 tctctttgtg gcggatacgc ttgaagtggc taatgcaaca ctgggtgccc ttcgtggacg
    18661 tattgctaaa gagcttggct tgattgataa tgataagttc aacttccttt gggtggttga
    18721 ctggccgatg tttgaatggt ctgaagaaga aggtcgctac atgagcgccc accatccatt
    18781 cacacttcca caggaagaga ctgctcacga attagaaggt gatttggcta aggttcgtgc
    18841 cattgcttac gatatcgtct tgaacggtta tgagcttggt ggtggtagcc ttcgtatcaa
    18901 ccaaaaagac cttcaagaac gcatgttcaa ggctcttggt ttctcagctg aagaagccaa
    18961 tgaccagttt ggtttccttc ttgaagccat ggactatggt ttcccaccac acggtggttt
    19021 ggctatcggg cttgatcgtt ttgtcatgtt gcttgctgga gaagaaaata tccgtgaagt
    19081 cattgccttt cctaagaaca acaaggcaac tgacccaatg acacaagctc catcaacagt
    19141 cgctctcaaa caactagagg aactcagctt acaagtagaa gaagatgaaa caagcaaaac
    19201 gaattaagcg gtggcgctat tatctgcgcc gctttgctta tcagataaaa attttacgtg
    19261 tcttacaaag tatctctcga gaaaagtatg atgagaagat ttcggcctct ctggtctatg
    19321 gttttttatc agcagtagca gttaatttct ttttccaacc agggcatgtg tattcgagtg
    19381 gtgcaacagg tctggcacag attatctctg ccttgagtaa tcactggttt ggttttcata
    19441 ttccgatttc gctaagcttc tacgccatta acttcccttt gatggtctta gcttggtatc
    19501 agattggcca taagttcacc gtctttacct ttatcacggt atctatgagt tccttcttta
    19561 tccagtttgt ccctgtggca accttgacgg aggatcccat tatcaattcc ctttttgggg
    19621 gtgttgttat gggtttgggg attggttttg ctcttcgaaa caatatctcc agtggtggga
    19681 cggatatcgt cagcctgact attcgcaaga aaacgggtaa gaatgtcggt agtatttctt
    19741 tcttggtaaa tggaactatc atgctgatag caggtttaac ctttggttgg aaatacgctc
    19801 tttattctat gattaccatc tttgtctcta gccgtgtgac agacgcagtc tttactaagc
    19861 aaaagcgtat gcaggccatg attgtgacaa atcatccaga gaaggtaatt gaaaaaatcc
    19921 ataaaaaatt gcaccgcgga gcaaccatga tccacgatgc agaaggaacc tataatcacg
    19981 agagaaaggc agttttaatc actgtcatta cacgtgcaga gtttaatgaa tttaaacaga
    20041 ttatgacaca agtggatcca agctcctttg tctctgtctc ggaaaatgtt catattctag
    20101 gaagatttgt tgagatagat aattagtgat taatactctt cgaaaatctc ttcaaaccac
    20161 gtcagcttca ccttgccgta tatatggtta ctgacttcgt cagtttcatc tacaacctca
    20221 aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa cctcaaaata gtgttttgag
    20281 caacctgcgg ctagcttcct agtttgcact ttgattttca ttgagtataa aaagatcttg
    20341 ggaaaagact caatttcagt agaaaaggaa gtaaatcttc ccacaataaa acgcatagta
    20401 tcaagttttt tcaatacctg atagtatgcg tttttgcttt taacgacttt ttgcccagtc
    20461 tcttattttt cgataatttt gtgggcgatc aattgacggt aacaaatttg tttattgttt
    20521 ttattatcat taataatctg gagaatagtt tcaagggaaa cacgaccaag ctctaaacta
    20581 ttgatatcga cataggctgc caagttgagc ttgggattaa ccgagtcaaa gctgagaaca
    20641 gggacatcca gctggtgttt ggcaatatag ttacaaacac cttcagctag gaggctatcg
    20701 gttgtgatga tagcatcaat ttgtggatcg tgcttgaata atcgcttgct aaatttatag
    20761 cccttttctt ccagaaactc gtcggcaaag tagatgcgat tgttgtcagt ggtaagtttg
    20821 taatgtttaa gcgcctgttc atagcctgtt aaacggtctt tggtcacgaa gagcttttta
    20881 cttcctccga taaaggcaat gcgtttgcag ccttttttga tgaaatattc agtcgcatca
    20941 aaaccagctt gaacattgtc gttgtcgaca agtgggatga aaggagatag agatttacct
    21001 aggataagga aggggaactg ttcttctgcg acgagtttta cgagagggtc ttcttcttgg
    21061 gcatagagaa agattagccc atctacacgc ttgccgtaga ccatttgtga aatagcgttg
    21121 agacgctcct tctcatcttt ccctgttgct atctgaatgg catagtggtt ttcagatgcg
    21181 acttgagaga tgccacgtag aaccgatgga aagaagggat tctggtagaa ggcgtctgag
    21241 tcatcaggaa gaactaatcc gataacctga gtatagctgc ttaccaagct acgagcgttg
    21301 aggtttgggt ggtagttgag ttccttcata gctttgcgaa cgcgtttttt tgtttcgtcg
    21361 ctaatggttg atttattttg aataacacgg gttacggttg aaggcgaaac accagcagcc
    21421 ttggccacgt ctttaatcgt aacgggcata aaaatctcct atttatggta atttggatca
    21481 cggaaatgtg ttttataaaa gatagtgacc agatacagaa caaaaagaat attttgtaca
    21541 gtaatcaggg ttgtcatatt ttggccaaat aatcccaaaa taagtgtaat cagagtcggc
    21601 aatcctaaac agttcaagat aaagtgatag cactctttaa aggttctaaa tgaaaagagg
    21661 cgtgatttct tagtgatata aaggagaaga ctagctccta gagagacgat aaagaaattc
    21721 aaaccaaaga ggaagctcgc accgagaact aggaagaggc tgatatagac acgattttgt
    21781 tggtaccagt ctttagaaat tgcttgggtc aagctgtctt tgcttttgaa actctcagtc
    21841 tgaatggctc ggtaagagat gcgggtcagc tccttgcttt ccttgctgat gactagctca
    21901 tttgtatcga aatgcagttg caagtcctta ggtaattcct tgatttgact tggaccaatc
    21961 acaacagaag gggtttgact agctgttcca gtataagtta atgtgccatc gacaattgta
    22021 gcatgttcag agagatcctg gacaacctca tttgtcagag gttcatagac attatcgata
    22081 aaagtttcta gcggataggt ctcctgggag ctgttttgga tagcaatggg taccatagac
    22141 aagctgataa ggaagatact ggtaaagaga agttgaaacc agttgagctc gaaacgtttg
    22201 gacaggggct tacgaaaccc ccaaatactt gaaaaatagg aaaatggata tggaagcata
    22261 ggtatctttc taaaaggtgt tttctatatg agtattatta tatagagaaa tgcgctttat
    22321 ttcaagtcta ggagaaaaat tgcttgctac aaggatatta tttacagtga caatcgctaa
    22381 tagtcaatga aaatcaaagt gcaaactagc cacaggttgc tcaaagcaca actttgaggt
    22441 tggagataaa gctgacgtgg tttgaagaga ttttcgaaga gtataaaatg aaaaagggtg
    22501 gcggggataa attatccctt gtcgccacca cttgtaagtc ctgaaacaaa gttcttttgt
    22561 aggaagaaga agagaataca gattggaagg gcgatgagga tagcacctgc tgagaagtag
    22621 gcaatcttca agtttttcgc attgttaacg aaggtttgga gacctacggc aacagtaaag
    22681 tattctttct cacgaagcaa gaaactagag aggatgtagt ccccgaaagg tcccatgaag
    22741 gcccagagag cttgtacggc aaccattggg cgaacaagtg gaagaacaat ttgccagaag
    22801 cggcggaagt gtcctgcacc gtctagtttt gcagattcgt ctaaagacat tggcactgta
    22861 tcgaagtagc ctttcatgag ccaagcattc atcgggatac caccaccaac gtagaggaag
    22921 atgaggaacc agttgtggtt aagggcgttc aacataagcg ccataacgaa gaaggctgtc
    22981 aaagcggcca tagttggcac catttggatg atcaagaaga agaccaaact ttgtttacga
    23041 gccaagaagt tgtaacggct gtaagcataa ccagcaagta cgatgatact tgtttgaaca
    23101 gccatggtaa ttaaggcgat aatcaaagtg ttgaggtacc aagtaccgta caaggtttca
    23161 gtgaagaggc ctttaaagtt atcaaaattg aggtcgatgt tagtatctag tttaaaggct
    23221 gagacgttac ctgctttaaa ggctgacata atggtaatca acagtggata gataattaca
    23281 attgatagac caatcaggta aaggtaagta aggctttgag tcagtctacg tttgagttta
    23341 attgagttat tcatcttaga cgtcctccat atcaaatgcg tgtagtttct tgaatgcgat
    23401 catagagatt gaaatgacaa tgatagagat gatcaaggta acagctgccg ccattgagta
    23461 ttgaggagat gtacctgttg tcaaacggta gatccatgag atcaagatat cggttgaacc
    23521 agctccacct ccgacactac caggtcctcc accattgaag aggtacatga tagagaagtt
    23581 gttaaagttg aaggtgtatt ggctaatcaa agtaggtgcc gcaacagcca aaatcattgg
    23641 gaaagtgatg ttgcggaatt tttgccaagc gttggcaccg tcaatataag ctgcttcgta
    23701 aaggtcgtta ggaatagatt gcaagatacc caaggtcaga acgtagatgt atgggaatcc
    23761 gagccaacct tgcatcataa tcaaggcaat cttagtccaa gttgggtctg ttttccaagg
    23821 aataagagct ccatcaagga aaggaaggaa tttagccaag attggcaata cttgagtgtt
    23881 gatagcaccg acactatcgt taaacatgtt tgagaatgtc aagatagtga tgaaggctgg
    23941 gacagcccaa ggaagaagga aaataacacc aaagatacgt tttcctttga taaatggttg
    24001 gttagcaatg atagctgtga agataccaat tacgatttgt aaagtagaag ctgccaaagc
    24061 ccaaatgata gtccaagaaa gaacagaacc aaaggcagaa cggaaggtac tcaagctcca
    24121 aatgtttgta aagttggtca aaccaaccca gtccaacaac ttgtttggtg gcaagtgttg
    24181 gaagtcgtag ttggtaaagg cgatcatcaa ggttacgata actgggaaga taatcgcgaa
    24241 ggtcatggca acataagatg gaatgatcaa gaggtaaggg aagccatttt cataaatccc
    24301 tttgatcatg tctttgagtg tgcgtggaac tggaattcca ttgttaatgc gttttgcaat
    24361 cgtatgtgca tctttgatat ttgagaaata aaagagtaca taaacgatta caaagattag
    24421 atggaaggca ccacgaatca gcataaagag ggaattatca cgacctggtt tgtcaccaag
    24481 agtgatgagg ttgctcaatt caggggttgc aagtgctagg aagtaaagga caaatacgat
    24541 ggttacacca aggaagataa aacctttggc tttttgttta ttgtaaatct gtcctaaccc
    24601 aggaatgata gacagcaggg ctgctttact aggttgttgc ttttccatat taactccttt
    24661 cataggatac tactttttta taagaaagct aaattatttg tgtctctatt gataaattca
    24721 aagggggatt tgatttccac cccccttgaa caaatttttt attcaccaaa tttttgtttg
    24781 attgtttctt tgatcaatgt tacagcatcg ttagcagctg ttttagcatc tttttgacca
    24841 cttacagcat caaagagcat atttttcgct ggatcccaaa ctgcagacat ttgagagatg
    24901 tttggcagtg gttgagtgtt cttgaactgt ttgataacag ctgttgtcaa ctcatcgttt
    24961 ttaccttcag cgtatgaacg agcctcagta ttagctggga tttcgttagt cttatcatat
    25021 aatacttttt gttgttcagt tgcaacaagg aagtctacaa atttttgaga agcttcaagg
    25081 ttcttaacgg cttgaggaat gacccaagct ttaccaccac cgaatgcagc atattctttt
    25141 ccatttggaa gagttgggat agttgcaact ccgtagttta ctttagcatc tttaaaggct
    25201 tgagctttcc aaggtccgtc gatgatagca gctgttttac cttcttggaa ttgagtttgg
    25261 attaagtttc cagcaccttc tgtatcttgc atacctttag gccatttttc gtaccaagat
    25321 ttagcgtagt tgatacctgc gatagaaccg tcgtttgcaa gaccgatgtc tttagcgtct
    25381 ttaccgtttt ggccaaagac gtaagcaccg ttaccggcaa gaagtccata tgtatagtag
    25441 aagtttgtcc agtcagctag gaaggcagta gttttaccat cttcaccagc gaatgcgtat
    25501 ttgctatctt tagcaaggtt ttccaagtca gcaaatgttt ttggagcatc tttcaccaag
    25561 tctttgttgt agtacataac aagtgactcg ataacggcag gagcaccgta aactttacca
    25621 ttagcagctg ttacaagaga tttagttgtg tcgtctgttt tagcaccatc gctcaatttc
    25681 acttctgaaa gttgtccgtc agaaccaagg ctacctacac ggtcgtatgg agccatcata
    25741 acatcaggga cattaccaga ttggttgtca agagaaagtt tatcaagacc tcctagagca
    25801 tcaccagttt taagagtgac ttttactcca gcttcttttt cataagcttt agcaacctct
    25861 tcaatatagc tcttatatcc ctcgtctaca tatacagtga gttctttgac ttcagatgaa
    25921 ccagaatcag caggcttatc agcagttttg cttccgcaag ctaccaaaag caagctagca
    25981 agtgtagcag ttccaagcac cgcagtgctc ttcataaatt tagatgacat agtgtattcc
    26041 tcccaaagaa tagcaagttt tattgataag gaaacgcaaa cgttttcctt tatgagctta
    26101 gtatagcaca aatagaaaac ggttgcaagt attttttgta aaaatttaaa aaaattttta
    26161 agcttgattt gatagcataa ttttacattt taatagaaga aaagtatgaa atagataaga
    26221 atacagtatt tttaataaaa atatatggaa tctgtctaaa gagggaaatc aggaggggct
    26281 acctccctgt ttctaatccc tatctatttt ctatagacgt ttgtgctttg ttgcatataa
    26341 attcaagctc cctaaggagg ttttgtactt tgtagactgt ctcgtgagag tcaaacttta
    26401 ggattagata gttttaagtt atctttgcta aaatgagtta gtctccttaa aaataatcaa
    26461 aaaagttttt taaaaacgct tgcaattatg cttgaaaagg agtatactta taagtaacgc
    26521 aaacgtttgc gtctgcaaaa tacgcaacgt tccattattt taacacacga ggtgctatta
    26581 tgaaaaaacg tcaaagtggt gtgttgatgc acatctcttc tcttccagga gcttacggaa
    26641 tcggatcatt tggtcaaagt gcttacgact tcgttgattt cttggtccgt acaaaacaac
    26701 gttactggca aatccttcca ttaggagcaa ctagttacgg ggattctcct taccaatctt
    26761 tctcagcctt cgcaggaaac actcatttta tcgatttaga tatcttggtg gagcaaggtt
    26821 tgttggaagc aagtgacctt gaaggagttg actttggtag cgatgcgtct gaagttgact
    26881 atgctaaaat ctactatgca cgtcgtcctc ttttagaaaa agcggtgaag cgtttctttg
    26941 aagtcggaga tgttaaagat tttgagaaat ttgctcaaga caaccaatca tggcttgagc
    27001 tctttgctga gtatatggct atcaaagagc attttgacaa tcttgcttgg actgaatggc
    27061 cagatgcaga tgctcgtgct cgtaaagctt cagcacttga aagctatcgt gagcaattgg
    27121 cagacaagtt ggtttaccac cgtgtgactc aatacttctt cttccaacaa tggttgaaat
    27181 tgaaagctta cgctaacgac aaccacatcg aaatcgttgg ggacatgcca atctacgtag
    27241 cggaagattc aagtgatatg tgggcaaatc cacatctctt caaaacagat gtcaatggta
    27301 aggctacttg tatcgcagga tgtccaccag atgagttttc tgtaactggt cagctttggg
    27361 gtaacccaat ctatgactgg gaagcaatgg acaaagacgg ctacaaatgg tggattgaac
    27421 gcttgcgtga aagcttcaaa atctacgata tcgttcgtat cgaccacttc cgtggcttcg
    27481 aatcttattg ggaaatccct gctggttccg atacagcagc acctggtgag tgggtgaaag
    27541 gtccaggcta caagcttttt gcagccgtta aggaagaact tggtgagcta aacatcatcg
    27601 cagaagacct tggcttcatg acagatgaag tgatcgaatt gcgtgaacgt actggcttcc
    27661 caggaatgaa gattcttcaa tttgccttca acccagaaga cgaaagcatt gatagcccac
    27721 acttggcacc tgctaactca gttatgtaca caggaacaca cgataacaat acggttcttg
    27781 gttggtaccg taatgagatt gatgatgcga ctcgtgagta catggctcgt tacacgaacc
    27841 gtaaagaata cgaaacagtg gtacacgcta tgcttcgtac agtattttca tcagttagct
    27901 ttatggcaat tgcaactatg caagatttac tagaattgga tgaggcagct cgtatgaact
    27961 tcccatctac ccttggtgga aactggtctt ggcgtatgac tgaagatcaa ttgacaccag
    28021 ctgtcgagga aggtttgctt gacttgacaa caatttatcg ccgaattaat gaaaatttgg
    28081 tagatttaaa gaaataagac aataatcagg agacaactaa acatgttatc actacaagaa
    28141 tttgtacaaa atcgttacaa taaaaccatt gcagaatgta gcaatgaaga gctttacctt
    28201 gctcttctta actacagcaa gcttgcaagc agccaaaaac cagtcaacac tggtaagaaa
    28261 aaagtttact acatctcagc tgagttcttg attggtaaac tcttgtcaaa caacttgatt
    28321 aaccttggtc tttacgacga tgttaaaaaa gaacttgcag ctgcaggtaa agacttgatc
    28381 gaagttgaag aagttgaatt ggaaccatct cttggtaatg gtggtttggg acgtttggct
    28441 gcctgcttta tcgactcaat tgctactctt ggtttgaatg gtgacggtgt tggtcttaac
    28501 taccactttg gtcttttcca acaagttctt aaaaacaacc aacaagaaac aattccaaat
    28561 gcatggttga cagagcaaaa ctggttggtt cgctcaagcc gtagctacca agtaccattt
    28621 gcagacttta ctttgacatc aactctttac gatattgatg ttactggtta tgaaacagcg
    28681 actaaaaacc gcttgcgttt gtttgacttg gattcagttg attcttctat tattaaagat
    28741 ggtatcaact ttgacaagac agatatcgct cgcaacttaa ctctcttcct ttacccagat
    28801 gatagtgacc gtcaaggtga attgctccgt atcttccaac aatacttcat ggtttcaaac
    28861 ggtgcgcaat tgatcatcga cgaagcaatc gaaaaaggaa gcaacttgca tgaccttgct
    28921 gactacgcag ttgtccaaat caacgatact cacccatcaa tggtgattcc tgaattgatt
    28981 cgtcttttga ctgcacgtgg tatcgagctt gacgaagcaa tctcaattgt tcgtagcatg
    29041 actgcctaca ctaaccacac aatccttgct gaggcgcttg aaaaatggcc tcttgaattc
    29101 ttgcaagaag tggttcctca cttggtacca atcatcgaag aattggaccg tcgtgtgaag
    29161 gcagagtaca aagatccagc tgttcaaatc atcgatgaga gcggacgtgt tcacatggct
    29221 cacatggata tccactacgg atacagtgtt aacggggttg cagcactcca tactgaaatc
    29281 ttgaaaaatt ctgagttgaa agccttctac gacctttacc cagaaaagtt caacaacaaa
    29341 acaaacggta tcactttccg tcgttggctt atgcatgcta acccaagatt gtctcactac
    29401 ttggatgaga ttcttggaga tggttggcac catgaagcag atgagcttga aaaacttttg
    29461 tcttatgaag acaaagcagc tgtcaaagaa aaattggaaa gcatcaaggc tcacaacaaa
    29521 cgtaaattgg ctcgtcactt gaaagaacac caaggtgtgg aaatcaatcc aaattctatc
    29581 tttgatatcc aaatcaaacg tcttcacgag tacaaacgcc aacaaatgaa cgctttgtac
    29641 gtgatccaca aataccttga catcaaagct ggtaacatcc ctgctcgtcc aatcacaatc
    29701 ttctttggtg gtaaagcagc tccagcctac acaatcgctc aagatatcat tcacttgatc
    29761 ctttgcatgt cagaagttat tgctaacgat ccagcagtag ctccacactt gcgagtagtt
    29821 atggttgaaa actacaacgt tactgcagca agcttcctta tcccagcatg tgatatctca
    29881 gaacaaatct cacttgcttc taaagaagct tcaggtactg gtaacatgaa attcatgttg
    29941 aacggagctt tgacacttgg tactatggac ggtgctaacg tggaaatcgc tgagttggtt
    30001 ggagaagaaa acatctacat cttcggtgaa gattcagaaa ctgttatcga cctttacgca
    30061 aaagcagctt acaaatcaag cgaattctac gctcgtgaag ctatcaaacc attggttgac
    30121 ttcatcgtta gtgatgcagt tcttgcagct ggaaacaaag agcgcttgga acgtctttac
    30181 aatgaattga tcaacaaaga ctggttcatg actcttcttg acttggaaga ctacatcaaa
    30241 gtcaaagagc aaatgcttgc tgactacgaa gaccgtgacg catggttgga taaagtcatc
    30301 gttaacattt ctaaagcagg attcttctca tctgaccgta caatcgctca gtataacgaa
    30361 gacatctggc acttgaacta atactcttcg aaaatctctt caaaccacgt cagctttatc
    30421 tgcaacctca aagcggtgct ttgagcaacc tgcggctagc ttcctagttt actctttggt
    30481 tttcattgag tataagatac aaatttatac taatacattt tgtaaaaaag cgagtttcga
    30541 ttgaaattcg cttttttaaa tgctgtagat ttgggtcaat cttgtctaaa aatagggaaa
    30601 tcctagatac agtgaagact ttaaatgctg gtttttactg tcctcagcct tatatttttt
    30661 cgtagttgat tacctcacac ctcttgtatt cgcttacata aagtattata atataattgt
    30721 aggaaagaag gtgtttttat gatatacaca cttaaattgg tgttgtttat tacctttctt
    30781 gtaataagct tgttacctga taagattttt ggaaaaaata aaaaaatttg gaaaatagtt
    30841 tttgcaatat tgacggcagt ggcagcattg tcatttatgt actaagttat tttaagaatg
    30901 tagggaaata aaccctacat tctttttagt tttttctgtt ttctaaattc tatttatcca
    30961 agcgcttcaa catttcttgc ttcttcgctt caagttctgc acgcttttct tcgatttcgg
    31021 catgtttttt ctcgagttca gaacaacttg caccattgct aaattctttt cgccatcagg
    31081 agatagggtg agtcgacatg tctattactc acccaaagca gtcctacaaa gcaggaattt
    31141 tctgttactt ttttggaaat agtaacgttt atacagcttt gacacttcgt atcaaagcgc
    31201 caaacacact ccgagggatt tacagaaagc agaaaaggaa tgatctggta taagatcatt
    31261 ccttttctct ctttttcttt aagtaattat atacaatgta cgacgaagtc gtcattgcaa
    31321 tgctgatcca ccacctaaag ggaactttaa acaacattga taagataaag aatataaaca
    31381 acgaaaatac gttataccca attaatttta ttgtatatct catgattaaa agttaatcct
    31441 tccgttgtta ggaatggcat catttttatc ccataattgt gctaaataag tccccggtga
    31501 taataaattc atagcggatt ctaaagcaac atcatttaca aaccaactac ctagatatct
    31561 agaaattgct gaacgaatag cactttttgc tgcatgtttt ccttttactt taattagatt
    31621 tgcaaggcct gcagtagttc ctcctaatgc taaagctatt gcagtatcta atagagcacc
    31681 catttgatta actgtaatac cttgccaagc tgctctaaat ggagagtatg taggtgggat
    31741 tgtataatcg ccttgtaatt gtcggttaat tacttctttg atccattgtt gtgagacgtc
    31801 tggatgaaaa gattggattt cgtttgcaag tgtattgatt tgttcttctg ttagagaagt
    31861 gacaggttga agttccatat ttgtttcaat ttgtgatact tgttcagaag cgtatacagc
    31921 tgaaacactt ggaatcgctg atacaattaa cacaattgac gtcaaaaaaa ccgaaataaa
    31981 tttcattaat ttgttcatga gcttttctcc tttttatttg tatctgctta cattttatta
    32041 tatactgtta ttatagtcaa gaaaaatatg ctattatgtt aaaaaaatat ttttaaaaat
    32101 ataaatggac ggatttattt tggattttat ttgttatttt gacctgcctc tatattggta
    32161 accatgattt gtttactctc aatcatcaag aattctcttt tcgtggtagc gtttggggtc
    32221 tggtactggc cttatatcac ttattgttca ttgataagtt tgtaatttcg aatcgaaaat
    32281 aaagattaga actatgattg actggctact tttaatattg attttggagg aagattttgt
    32341 ctctattatt tattatttta aatttattta ttttgtataa gatctattct ttgaggcggg
    32401 aaaaatcgaa atacttgatt tatacggcct atatcatatt tggggtaaat gtagtatatg
    32461 gtattcaatg gttattaaga gaactgattt caactatttc cccttaatgt gtatggaaac
    32521 tataacaaaa cgcataagat taaggtttgt gtacctgttc ttatacgttt ttgtaatatt
    32581 gaagattttc ggtaagtttt atacctttgg gaagtctagt ttagaatgct ttcccaacca
    32641 aaatctctgc ttcgatggta atctctgtca gttggctcca gtcaatcttg ctctggtcaa
    32701 catgaaagag gagaggagtc atactgagta gggcttggag ttgttctgct gtgatagtct
    32761 tagtcagaga ggcagtttga ctagatagga tggtaaagtg ctcctggaaa tgctccttga
    32821 tatcttggtt agaatactcc ttgtttgtca gctggtcctg tactctttga cggatttctt
    32881 tgaggtgatt ttcagttggg ataaccttta tcaagatacc gtctttggat aaaacgcgac
    32941 gaaattctcc atagttggca ggtgagaaga tatcaagcag aatatccatg ttagcgtctt
    33001 ttataggaag tcgtgccaag tcgccaacga accaattgac tgcccagttg ggttcacttt
    33061 tagcagcgat ttggactgaa tctttggaga tgtcaaaggc atagaaagtt ttttcagagt
    33121 gactttcttg tagtttgcga gaatagaatc cttcaccaca accgatatcc aaaattgttg
    33181 tggtagtttt tgagcttgca agcaagtcag atacagcatc taagatagct tggtaaaagc
    33241 cggcttctag gatttgttga cggttttgaa aattttcctt gtcgtagtta gcagattgct
    33301 tgatttgagg tgctagattg acatagccaa atttcgccaa gtcaaaagaa tgacggttgc
    33361 agcacttgaa attagtctct aacagagtca gattttcttg acagatagga caggcaaagg
    33421 cagtcgcaga agcaaaacgc tgaagtttgg gcttgagatt tgtattcata gtttaagtgt
    33481 atcaaaagag gcaaatgaaa gcaactttag gaataagtag atgggagatt cagtagaaat
    33541 aaaactaatt ctccaattta tagaatgaaa ttgcttttat atctaaattg ctatataata
    33601 atgataagga ggaaataagt atgttaaaag aagtattaac cgttgcaaaa gttgcgaaaa
    33661 aatcttcatt atttttgggt ggtgtcgcat ttggtaccct tggtttgaaa atcttagcaa
    33721 gtaaggaagc taaaaaaggt tattctaaag ctttggctaa ggcttacaag ttgaaagacg
    33781 agctagatgc atctgtttct gttgtgaagc aacatggaga cgatgtcttg caagatgcca
    33841 aatatttgta cgagcaagag aaaaaagaag agcaattaga tagccttata ggtgaataat
    33901 atgtctttta aagtgctaca tagaggatac caacatatcc gactatcatc ttctttttca
    33961 cttaccttgg atattcaaga ctatcttcgt tccttggcga gagatgaaaa ggggattgag
    34021 tctatccagt tttacatgga tcaacagcac tttactctac gcataaaaga aggcttttct
    34081 gtattagata atgcagaagc ctttttaaaa agaattgata aagggaaagt ttctgagttg
    34141 atgactcttc ccattcgtag agaagagagt gcttattcta ttgtttcagg tgcagcggtt
    34201 aagcgtgtac tttttcgtag ttttgtgccg tatcctattc gctatatatg gacttgttat
    34261 caggctttgg gttatattag agaagcctat caaacactag cgcgtaagga actaacgatg
    34321 gaagtcttgg actgttcggc tattttattg tccttgttta tgaaccaatc caagacagct
    34381 agcaatatca tgtttatgct tgatttgggg aatcatttag atcagtggtc cttgaaaaaa
    34441 actgcaacag atttagaaca gagtcttctt gcaaaagaga gcgatgtatt cctagtacag
    34501 ggcgatacgg ttgttagtat aaagagttcc gatgttcaaa taggagatgt cttgatctta
    34561 tctcaaggaa atgaaattct gtttgatggg caagtagttt caggtttagg tatggtcaac
    34621 gaaagttcct tgacaggaga gagttttcca gttgaaaaaa gagagtctga tttggtttgt
    34681 gcaaatacag tattagaaac tggagagtta cgcattcgtg taacagataa tcagatgaac
    34741 agccgtattt tacagctgat tgagttgatg aagaaatctg aagaaaacaa gaaaacgaaa
    34801 caacgctatt tcatcaagat ggcggataaa gtcgtcaaat ataatttctt gggggctggg
    34861 ctgacttacc tattgacagg ttctttttct aaggctattt ctttcctatt ggtcgatttc
    34921 tcctgcgctt tgaaaatctc tactcctgta gcttatttga cagttatcaa ggaagggttg
    34981 aaccgtgaaa tggtgattaa ggatggagat gttctggaga aatatctgga agttgatact
    35041 ttcttgtttg ataagacagg aacaatcaca actagttatc ctatagttga aaaggtgtta
    35101 ccttttggag actatagtga ggaagatatt ctcagaatca gtgcctgtct tgaggaacac
    35161 atttatcatc ctattgctaa tgccatcgtc aagcaagctg agatagaggg aattgaacat
    35221 gaggaaatgc atgggaaact ccaatatatc gcaagcaagg ggatcaaatc tcatatagat
    35281 ggccaaccag ttcttattgg gaattatgtc ttgatgcagg atgagcagat tcatatcagt
    35341 tcagaacaaa atgctttaat tgaagagtac aagagtcact acaatctctt attcttggct
    35401 tatcaaaatg aattgattgg aatgttctgc attcatactc ctttgagaaa agaagcaaaa
    35461 acagccttgg ataaacttaa ggcacagggg aaaaaattga ttctggcaac aggagacacc
    35521 ttgattagga cagaggaatt agtcaaagat ttgccctttg atcaggtcta tacagacttg
    35581 aaacctgatg ggaaatttga gttagtagag aaactgcaga aagcaggtca cactattttg
    35641 atggttggag atggattgaa tgactcagcg gctctaactc tatcagatat cggtgtggtg
    35701 atgaatgaga gtgcagatat ttctaagcag atgagtgata tcttattgtt agataatcgt
    35761 ttggatttct tccaagagtt ggattcgtta tcatcatctt tgcaaacact catcaagaaa
    35821 aatattcaag ataccgttgt cgtaaatagt agtttgattg gctttggctt atttaattgg
    35881 ctcagtcctt caaatctctc tatcttacat aatctaacaa ccttgcgcat tgtcctgcgt
    35941 agcctgtcta ttaaaaatag atagatgaga gttattaaca gcaaaaagga gttacctttc
    36001 tcgaggttaa ctcctttgtt tatagataaa tgttgaatag tttagtaagt caatacaaag
    36061 tattttttct tcccacgacg gataacagtc agttcatttt ctaacttatc agcgtcactc
    36121 aagacatagt caaggtcttg gatgcggccg ccgtttacgt agatggctcc gttttggacg
    36181 tcttcacggg cttggcgttt tgagttaact ataccagatg agacgagcag ttccacgata
    36241 ttgttgtgtt cgtctgcctg tacttggtag tttggcacac cacgaagtcc ttgtttgagc
    36301 tctttgacag aaaggttttt gatgtttcct gcaaagagtt gctcagtgat gttaagtgct
    36361 tctttgtagg cttcttctcc gtgaacaagt gtaacaactt cacgagccaa gactttttga
    36421 gccaagcgtt cgtgtggcgc tgcttcaaat tgtttgcgaa tatcttcaat ctcatcaagt
    36481 gacaagaaag taaagatttt caagaagcga acagcgtcag cgtccatcac gttcatccag
    36541 aattggtaca tttcgtatgg agaagtcttt tcgggattga gccagacggc atttccttct
    36601 gatttaccaa atttcttacc agttgcatct gtgattagtg gaacagtgat aacgtgacca
    36661 gtcttgtccg ccttacgacg aagcaattcg gtaccagctg tcatatttcc ccactggtca
    36721 gaaccaccga tttgaagagt gacattatgg tcttggttaa ggacgaagaa gtcgtaccct
    36781 tgcatgattt ggtaagcgaa ctcagtgtaa gaaattcctg tttcgatccg ttttttaaca
    36841 gattccttac tcatcatgta gttgaccgtg aagtattttc caatatcacg gaggaagtca
    36901 atgaagctga tgctgccaaa ccagtcgtag ttgttgacca tgacagcctt gttttcgcca
    36961 ttttcaaagt caagaaaacg agaaagttgt ccttggatag acttgaccca gccatctact
    37021 gtgtcttttg tttggagact acgttcagca tctttgaagg acggatctcc gatgagacct
    37081 gtagcaccgc caacgagcgc ataaggtttg tgacctgcta gttgcaagcg acgacttgtc
    37141 aagattgcga caaggtggcc taggtgaagg ctgtcagcag ttggatcgta gccagtataa
    37201 taagaaactt gaccttcttc tagggcttta cgcaaagctt cttcatcagt cgtttgaaat
    37261 atcaaaccac gctcttttag ctcatcaaaa atgtgcatgt gtcttttctc ctttttaaaa
    37321 ttattgtttc tacctattgt atcacaaact tgggcaatag cctagcagaa tagggaagaa
    37381 agtggctatt ttattgaaaa tttccctttt gtggtataat agataaagtg aggaaatcca
    37441 tgcaaaatca attaaatgaa ttaaaacgaa aaatgctgga atttttccag caaaaacaaa
    37501 aaaataaaaa atcagctaga cctggcaaga aaggttcaag taccaaaaaa tctaaaacct
    37561 tagataagtc agccattttc ccagctattt tactgagtat aaaagcctta tttaacttac
    37621 tctttgtact cggttttcta ggaggaatgt tgggagttgg gattgctttg gggtacggag
    37681 tggccttatt tgacaaggtt cgggtgcctc agacagaaga attggtgaat caggtcaagg
    37741 acatctcttc tatttcagag attacctatt cggacgggac ggtgattgct tccatagaga
    37801 gtgatttgtt gcgcacttct atctcatctg agcaaatttc ggaaaatctg aagaaggcta
    37861 tcattgcgac agaagatgaa cactttaaag aacataaggg tgtagtaccc aaggcggtga
    37921 ttcgtgcgac cttggggaaa tttgtaggtt tgggttcctc tagtgggggt tcaaccttga
    37981 cccagcaact aattaaacag caggtggttg gggatgcgcc gaccttggct cgtaaggcgg
    38041 cagagattgt ggatgctctt gccttggaac gcgccatgaa taaagatgag attttaacga
    38101 cctatctcaa tgtggctccc tttggccgaa ataataaggg acagaatatt gcaggggctc
    38161 ggcaagcagc tgagggaatt ttcggtgtag atgccagtca gttgactgtt cctcaagcag
    38221 catttttagc aggacttcca cagagtccca ttacttactc tccttatgaa aatactgggg
    38281 agttgaagag tgatgaagac ctagaaattg gcttaagacg ggctaaggca gttctttaca
    38341 gtatgtatcg tacaggtgca ttaagcaaag acgagtattc tcagtacaag gattatgacc
    38401 ttaaacagga ctttttacca tcgggcacgg ttacaggaat ttcacgagac tatttatatt
    38461 ttacaacttt ggcagaagct caagaacgta tgtatgacta tctagctcag agagacaatg
    38521 tctccgctaa ggagttgaaa aatgaggcaa ctcagaagtt ttatcgagat ttggcagcca
    38581 aggaaattga aaatggtggt tataagatta ctactaccat agatcagaaa attcattctg
    38641 ccatgcaaag tgcggttgct gattatggct atcttttaga cgatggaaca ggtcgtgtag
    38701 aagtagggaa tgtcttgatg gacaaccaaa caggtgctat tctaggcttt gtaggtggtc
    38761 gtaattatca agaaaatcaa aataatcatg cctttgatac caaacgttcg ccagcttcta
    38821 ctaccaagcc cttgctggcc tacggtattg ctattgacca gggcttgatg ggaagtgaaa
    38881 cgattctatc taactatcca acaaactttg ctaatggcaa tccgattatg tatgctaata
    38941 gcaagggaac aggaatgatg accttgggag aagctctgaa ctattcatgg aatatccctg
    39001 cttactggac ctatcgtatg ctccgtgaaa agggtgttga tgtcaagggt tatatggaaa
    39061 agatgggtta cgagattcct gagtacggta ttgagagctt gccaatgggt ggtggtattg
    39121 aagtcacagt tgcccagcat accaatggct atcagacctt agctaataat ggagtttatc
    39181 atcagaagca tgtgatttca aagattgaag cagcagatgg tagagtggtg tatgagtatc
    39241 aggataaacc ggttcaagtc tattcaaaag ctactgcgac gattatgcag ggattgctac
    39301 gagaagttct atcttctcgt gtgacaacaa ccttcaagtc taacctgact tctttaaatc
    39361 ctactctggc taatgcagat tggattggga agactggtac aaccaaccaa gacgaaaata
    39421 tgtggctcat gctttcgaca cctagattaa ccctaggtgg ctggattggg catgatgata
    39481 atcattcatt gtcacgtaga gcaggttatt ctaataactc taattacatg gctcatctgg
    39541 taaatgcgat tcagcaagct tccccaagca tttgggggaa cgagcgcttt gctttagatc
    39601 ctagtgtagt gaaatcggaa gtcttgaaat caacaggtca aaaaccaggg aaggtttctg
    39661 ttgaaggaaa agaagtagag gtcacaggtt cgactgttac cagctattgg gctaataagt
    39721 caggagcgcc agcgacaagt tatcgctttg ctattggcgg aagtgatgcg gattatcaga
    39781 atgcttggtc tagtattgtg gggagtctac caactccatc cagctccagc agttcaagta
    39841 gtagttctag cgatagcagt aactcaagta ctacacgacc ttcttcttca agggcgagac
    39901 gataattctc taaatgaagt ggccaatcaa tggattgcca cttttttcct ttcgtgttac
    39961 aataagggta tgaatcagta tcagaaaaag attgttaacg gaaaaattta ttcgctccta
    40021 tccggcttaa tatggggaat ctgtggaatt ttaggagagt acttctttac tcattatcag
    40081 gtgtcttcgg gctggattac ctctatgcgt ttgacactgg cagggagtct tgtactcatt
    40141 tggtctgcaa tacaattaaa atcgcaagtg ctagatattt ggcgagacaa gaaaaattac
    40201 ctgccctttt tagcctatgc tattttgggg attttttcag ttcagtattt tttctatctc
    40261 tgtgtagaat actcaaatgc tacgacagca actattttac agtttattag ccctgtcttt
    40321 atcctctttt acaatcgctt ggtttatcaa aaacgagcgt caaaaagcgc tgttttctat
    40381 gttttggttg ccatgctggg tgtttgcttg atggcgacaa agggagatct ctctcagtta
    40441 tccatgacgc cgctagctct tataacaggt ttgctgagtg ccatgggtgt tatgtttaat
    40501 gttatcttgc cccaaccttt tgctaagcgt tatggttttg ttcctacggt tgggtggggg
    40561 atgattttgg caggtttgtt tagcaatgtc ctctcgccgg tttatcagct ttcctttact
    40621 cttgatattt ggagtatctt gatttgcctc attatcgctt tctttggaac ggcttttgct
    40681 tttttcattt ccatgaaggc tgtgtccttg gtttctcctt tggtggtttc cgttatcagt
    40741 gccagtgaac ctctctcttc tgctctcttg agtgttttgt tcttaggatt agtagtggat
    40801 tggtccctcc ttctagctat agtcttgatt attttaccca tgatattttt gtctatagaa
    40861 gaagcgaaag aaagtagata aaaagtcttt tcttaattct aaaagtgtgc tatactagaa
    40921 tagtcaataa aacacgggga gatagttgtg aagagtgttt ttaggttgta tcggtagggg
    40981 cttgctttta ccgacagcac gttttatctc acaaccctaa aaaatcatac ctaaaaacag
    41041 acaaaaaggt ttcaaatttg aggccttttt tggtagaata ggtatcatta taacgaacca
    41101 ggaggcacct atgactgcta caaaaatgaa cgctcaagaa attatccaat ttatcgccaa
    41161 tgctgaaaag aaaaccagtg tcaaagtaac ctttgagggg caactcgcaa ctgctgtgcc
    41221 tagctctgtt gtcaaactag gaaatgtcct attcggagac tggaaggacg tggctccgct
    41281 tcttgaaggt ttggtagaaa atcaagatta tgttgtcgag caagatgctc gtaattctgc
    41341 agttcctttg ctagataagc gtgctatcaa cgctcgtatc gagccaggtg ctattatccg
    41401 tgaccaagtg gaaattggtg acaatgctgt tatcatgatg ggagctgtta tcaatatcgg
    41461 tgctgaaatc ggtgctggaa ccatgattga catgggtgcc atccttggtg gccgtgccat
    41521 cgttggaaaa aatagccacg ttggtgcagg tgcagttttg gcaggtgtga ttgagccagc
    41581 tagtgctgaa ccagtccgtg tcggagacaa tgttcttatc ggtgctaatg cagtggttat
    41641 cgaaggagtc caaatcggta gtggttcagt tgtcgcagca ggagctattg ttacccaaga
    41701 tgtcccagaa aacgtggtag tagcaggtgt tccagctcgt attatcaaag aaattgatgc
    41761 ccaaactcaa caaaaaacag cgctagagga tgcgcttcgt accttgtaat tgtaaaagta
    41821 aaaaagaggc ggaacccttt ttccagcctc tttctgctat atcggaggac agatagatgt
    41881 tagatttgat tcagactaga cgagatttac accagatacc agagattggc ttggaggagt
    41941 tcaagactca ggcttatttg ctggatgtga ttgagaaatt gactacgggc aaggattttg
    42001 ttcaaattcg tacttggcgg acagggattt tggtctacct gcagggaagt cagccggagc
    42061 gaaccattgg ttggcggaca gatattgatg gcctgcctat cgtcgaacaa acaggtctac
    42121 cttttgcttc tcaacaccaa ggtcgcatgc atgcctgtgg tcatgatttt catatgacca
    42181 ttgccttagg ctgtcttgag cgcgcccttg aggagcaacc caagaataat ctgctctttc
    42241 tatttcagcc tgctgaagaa aatgaagctg gtggtatgct catgtatgag gacggtgctt
    42301 ttggagattg gttgccaaac caattctatg gtctccatgt tcgtccagat ttgaaagtcg
    42361 gccagattgc gactaatact catacactct ttgcaggaac ttgcgaggtg aagatccgtt
    42421 tcaaaggcaa aggtggccac gcagcttttc ctcatgaagc caatgacgcc ttggtggcgg
    42481 ctagttactt tgtgacccaa gtgcagtcag ttgttagccg caatgtcaac ccaatcgagg
    42541 gagcagtggt gaccttcggc gtttttcaag ctggaaccac caacaatgtc atcacagaca
    42601 cagctttttt acatggaact attcgtgcct tgacacagga catgagtctc ttggtgcaaa
    42661 agagggtaaa aacagttgca gaaggggttg cagctgcctt tgatatggaa gtcgaagtgg
    42721 aactcaaaca aggtggatac ctacctgttg agaacaatcc agccttggcg cgtgaactga
    42781 tggacttctt tgacgagaaa gacggaatcg agttgattga tatcgaacct gctatgacag
    42841 gcgaggactt tggttatctc ctttcaaagg ttgatggcgt gatgttttgg ctaggtatcg
    42901 atagtcccta cgctcttcat caccctcaaa tgagtcctaa ggaagaagtc ttagctattg
    42961 gggtggctgc ggtgtctagt ttcctgaaaa agaaggcagc agaatagagg gcttgtctat
    43021 gaaatcggaa ttacgcaagc aagtcttgca tgaaatgaag gctttatctc aagaacaaaa
    43081 acaggctata gaccaagctt taaccgagcg aattttacaa cacccctttt atcaagaagc
    43141 caaggtcatc gcaacctacc tctctttttc tcatgagttt caaacgcggg aactgattga
    43201 gcaggcgctg aaggacggca agagggttct gacacctaag acctatccca aggggcgcat
    43261 ggactttgtg gtctatgatc cgcaacagtt ggtaaaaact gcctttgcct tactggagcc
    43321 acagggagat ttggaagtgg tggatgtatc tcagattgat ttgattcatg ttcctggcct
    43381 ggcttttacg acggatggat atcggattgg atatggtgga ggttattatg accgctatct
    43441 ggaacatttt tctggtcata ctttgagtac ggttcatcct tgtcaaattc aggactttat
    43501 acctgaaaac catgatattc ctgttcagga ggtattaatt gatgaaggaa atctttgata
    43561 gacgttaccc tgtgacgagt ttcttcctct tagtgacggc cttggtattt ttactaatgt
    43621 tggtcactgc aggcggaaac tttgacaggg cagatacatt atttcgattt ggagccatgt
    43681 atgggccagc tattcgcctc tttcccgagc aggtttggcg tctcttgtct gccatttttg
    43741 ttcatattgg gtgggaacat ttcattgtta atatgctttc actttattat cttggaaggc
    43801 aggtagagga gattttcggc tctaagcagt tcttttttct ctatctctta tcaggaatga
    43861 tgggcaatct ctttgttttt gtatttagtc ctaaatcctt agcagcaggc gcctctacct
    43921 ctctttatgg gctatttgcc gcgattatca ttcttcgcta tgcaactcgc aatccttata
    43981 tccaacagct agggcaatcc tatctgacac tttttgtggt taacattatt ggaagtgttc
    44041 tgattccagg aatcagccta gcaggccata tcggtggtgc agttggtggc gcatttctag
    44101 cagttatctt tccagttaga ggagaaaaac ggatgtataa caccagccag agattaggag
    44161 cggtagtctt gttcgtagga ctcgccattt tgcttttcta caagggaatg ggaatgtgac
    44221 gaagttgaaa gaaaatttgt gtaatgaaaa aagataaggc attttttgaa ccttatcttt
    44281 ttattttatt ccttctcagt caattctttt ccaagttgga tgaggtaatt cttcaaatca
    44341 tctttgactt gtggatgttt gagggcgtag tcaatagatg ttttcataaa gccaaactta
    44401 tccccaacgt cgtaacgagc tcctgtaaat tcacgggcaa aaacacgctg tgttttatta
    44461 agagtatcga ttgcatcagt aagttggatt tcatttccag caccaggagc ttggttttcg
    44521 aggatttgga aaatttcagg cgtgaggagg tagcgtccga taatagcaag gtcgctagga
    44581 gcgtcctctg gagctggttt ttcaacaaag gtttcaacac tgtaaagacc atcttttcct
    44641 tcgccttgcg gagcaataac cccgtaagca gatacttcgt catgagggac tggcatgaca
    44701 gcgatagtag acgcgtgggt acgcttgtag tcatccatga gttgtttggt aagtggaaca
    44761 gccttttcgt ctgtgatatc catcaagtca tcaccaagca taacgacaaa aggttcattt
    44821 ccgacgaaag ccttggcttg caaaacagca tctccgagac cgcgtggatg agtttggcgg
    44881 ataaaatgca gacgcatgcc agttgtttca tcaactagct tcaaaagatc tgttttccct
    44941 ttttctttga ggttatattc caattcgaag tttgaatcga agtggtcctc aatagaacgt
    45001 tttgatttac cagtgacaac tagaatatct tcaatacctg atttgagagc ctcttccacg
    45061 ataaactgga tagttggttt gtctacgatt ggcaacattt ctttggcaag ggccttggtt
    45121 gctggtaaaa atcgagttcc tagtccagca gcagggataa ctgcctttct aacttttgat
    45181 gtcataaaaa tcctttctat agagggttaa gaccactcat tttctgcttt aaattcattg
    45241 ttcatgatgt cataaatggc atctttgata ttggttccgt gataaataac ttggtaaata
    45301 gcctgtgtaa tgggcatata gactccaagt tcttgggcta gttcataggc tgctcgagtc
    45361 gttgaaattc cttcgattac catgcccata ttagcttcta tatcagctag ggattctcct
    45421 cgtccgagag catctccagc tctccagtta cgagagtgga tggaagttcc cgttacgatc
    45481 aaatctccca caccagataa gccgctatag gtcaatggac tggccccgag tgctacccct
    45541 aggcgggtga tttctgctaa acctcgagcg atgatggctg ccttagcatt atcaccaaat
    45601 ccaagaccat gtaaagctcc agcaccgaca gcaataatat ttttaagagc accagcagtt
    45661 tcaaccccga taacatccgt attggtataa agtcggaagt agtgattact aaatagctcc
    45721 tgaacgtatt gagctgtttg taaatcttta gaagcagcag ttattaaagt taggtcacgc
    45781 acaatggtct cttctgcatg actaggccct gaaacaacga cgatatcact acggagatgt
    45841 tcaggaattt cttcttcaag aatggttgat aatcgtttat ggctatcagg ttctaatccc
    45901 tttgatgcgt gcatgatgat aaccttatgg tccaaggttt gtgcaacttg ctgggcaaca
    45961 agtcgtgtca cttttgttgg gacaacaaac aaaatcgcat ccacattttt caatgtttct
    46021 gctaagtcgg tgtaggcaat gatattttcg tctagaacga catctttaaa gtagtgctta
    46081 ttagtatggt gtgtattaat ttcattgatt tgctcgggaa gatttcccca aatacgtacc
    46141 tcgtgtccat tgtcatttaa gacttgtgaa agggcggttc cccaagaacc aggccccaag
    46201 acggcgacgg tttgtttttc catgatttcc tccttgatag atttctttct cttattctat
    46261 catattctag gggattttgc acttgcatta ctggggtatg gtggaaaaat acacaaagac
    46321 cgagatgaag ggataaactc ttagtcttta gttaaagtga gaagaaatct gatagatagt
    46381 ttgattcagt atatgcttat aatagaggta aacaactcag gaagttcttg taggttgcga
    46441 gagtttggcg aaaaaattaa aagattacgt ttggctaaaa aaatcagtcg ttcagaattt
    46501 tgtggtgatg agtctgaatt aagtatccgt caattaatta gaattgaaaa tggagaatcc
    46561 agaccaacac taacaaagtt aaaatatatt gctgaacgtt tggaggttga agattacaag
    46621 ttgatgccaa gttatataga gttggataag gaatacctag aattgaagta tttcttgatg
    46681 aggactccta catacgaaga tgaaactatc gcccaaaaga aagagagtgt ttttgataag
    46741 atttttgaag agtattatga taggctacct gaggaagaaa gatttatcat cccaaattat
    46801 tcatatctag cactagcgaa ctacacagtt caaaaattac cagaaaagct agttgaaata
    46861 ctgtccttct ggtgattttg cttaatttct gatgttcgag acatgattga ggagatttgt
    46921 cttgattttt tcctaaaaaa gggcagactc ctcccttggt ttgatgctcg atttttaaaa
    46981 taaggtgact tattctgtta ggcagttttc ccctgccctc tagctctata tggaacaggg
    47041 agtatcagat ttatctggca gattgtatca aataaggctt gaaactgttt tgaataggcg
    47101 tatagacttg agaatttgag aatatgtcgt ctagcagtag agacatattt tccggcaata
    47161 tgaaggaaga gacgtcgaaa acgcttgata gtcaaggcct ttacttcatc accagctagc
    47221 tgctttaaaa agaggtagag attataagcc agacagccca tcatcatacg tacttcattc
    47281 ttaatcatgg tcgaactatc tgtcttatcc ccaaagaatc ctgctttcct ttctttgata
    47341 aagttttcag cattccctcg ttcacgatag aattgaaaca gctcctcact atctacactg
    47401 cttaaattgg tcaaatgaac ttttttacaa ccataaaaaa gagcacttaa tcgtactctt
    47461 ctcttttaag gattagttga attaattcaa atccactagt tctcctgttt ctaggtagac
    47521 taggcgttca caaatgttag caatgtaatc agcgaagcgt tccagatgcc ctatgatata
    47581 aaggtattga gttccattgg gaattgaggt ttcttggtct ttcataagtc caatgatttc
    47641 ctttgataag gcataataat attggtcaat ctgttcatct ttttgagcaa tactaatagc
    47701 ttttgaggct tggtgcaaag gaaaggcaac caataaatcg gctagcatgc tgagggataa
    47761 tttacccatt tggtgtaact gttcttcgtc aggggctagt tgattttctt ttagttgcaa
    47821 aacagctttg gcaatgcctg ccatatggtc tcccatacgt tcaaggtctg aacaagaaga
    47881 catgatgcta atcacaaatc gaaggtcaga cacttgtggc tgctgcaagg ccaacaaacg
    47941 ggcacaggtc aattcgatag cgctttgacc ttggttgata gcatgatcct tattgataat
    48001 tagctctgcc atctccttgt ctttggaggc taaggccagt aaggtttttg aagctgtttc
    48061 aaggacaagt tgccctagtc ctaaaaagga ttgttctaat tcatgcaatt ctaagtcaaa
    48121 ttgatttctc ataggttttt ccttccttat ccgaaccgtc ctgaaatata gtcttctgtg
    48181 cgctgatctt ttggattggt aaacacgtca acggtgtctc caaattcgca aatttctcct
    48241 gttaagaaaa aagcagtttt atctgaaata cgtgaagctt gttgcatgtt atgggtaaca
    48301 atgataatcg tataatcctt ttttagttgc tgaatgaggt cttcaatttt taaagtggag
    48361 atagggtcta aggctgaagt cggctcatcc attaacagaa tatcaggttc tactgctaaa
    48421 gctcgcgcaa tgcaaaggcg ttgctgctga ccgccagata aggacatggc actcttttta
    48481 agatcatctt tgacttcttc ccaaatggct gcccctttta aagatttctc cactaaggca
    48541 tctaattgtt ttttgtctcg aataccatgt gtccttgggc cataagccac gttatcatag
    48601 atagacatgg caaagggatt aggctgttga aaaaccatcc ctacacgctt acgtagctga
    48661 ttaaggttga atttgctact ataaatatct tgctcatcta agaggacttg gccttcaata
    48721 tggcaagaag gaaccaaatc gttcatccga ttaagggttt ttagaaaagt tgatttgcca
    48781 caaccagatg ggcctatcaa ggcagtaatc tgtctttctg gtaattgaat cgaaatattt
    48841 tttaaggctt gaaaatcccc gtaaaataag tctaggtgtc taactgaaaa tgttcccata
    48901 ctaggaagct cctttcacaa gtttccgaga taataagctt gatagagtat ttatcattaa
    48961 aacagtaata atcaaaatca cgccggtagc ataggcttca ttgacatgta gcccctcact
    49021 tgacagcata tacatatgta gggctagaga acggcctgaa gacatgagac tacttggcgt
    49081 attggtagag gtacctaatg tatacatgag ggcagctgtt tcaccaacga tacggccaat
    49141 agctagtatc actccagcta aaatacctgg catggcaact ggtagaacaa ttctaaaaac
    49201 agtccgtaac ttacctgccc caagtccata acttgcttga cgcatgctat cactaacaga
    49261 taaaagggct tcttctgttg agcgaataat gactggcaac accatgataa ctgaggttaa
    49321 gattcctgat aacagagagt attgaaaacc taagaagact acaaagaaga gcatgccaaa
    49381 cagaccaaaa acaatggaag gaatcccaga caaggtatct gaggccaatc gcatgatttt
    49441 aacacaaagg gaatcttttt ttgtatattc cacaagataa aaaccagcaa aaatccctat
    49501 gggcaaggct aaaagaagag caccaaaaac cagaataacg gtggaaataa tcgctggcat
    49561 aagggaaatg ttctcagaag tataagtcca agaaaagagg gatagactta gatgaggtaa
    49621 gcctttgatg aggataaaac caatgattaa aaagagagag ccaaaggtta aagctgaaaa
    49681 acaataaacg agaagtttta gcaggtattt actcataaga tgattttcct ttcaagtagg
    49741 caaagtaggc attaatcaag agaataagga aaaagagaac tgctgaggtt gcaataaggg
    49801 cttccctatg ctgacctgat gcgtaagcca tttccagaac aatattggtt gttaaggttc
    49861 tggttcctga aaagagtcca cttggaataa tcggctggtt gcctgccacc aaaataactg
    49921 ccatggtttc acctactgcg cgaccgattc ctaaaataac tgctgataaa ataccagatc
    49981 tcgcagctgg caagatgaca ctaaaaatac tccgttcatg actagctcct agagccaagc
    50041 taccagaata atacgttttg ggaactgttc ggatagcaga ttctgacaaa ctgataatgg
    50101 ttggcaaaat cattattcct aatagtaacg aagcggttag gacactcatg ccatttccta
    50161 aaaagcttct aatccaaggc accaataatt gtaggccgaa aaaaccataa acaatagatg
    50221 gaatggccgc catcaagttg atagctgatt ttaagaagcc atagacgggc tttggacaat
    50281 aataaaccat aaacaccgat gtcaagatgc ctgttggcac cccaatcaca atcgctccta
    50341 aggtaattaa taaggaacca acgatcattg gtaaaatacc atagcttgcc ggaatgttcg
    50401 ttggcgacca atcactgcct aataaaaaac gggcaaagcc gtagttagcc atgaaaggta
    50461 agccattact aaaaataaag aaacagatta gcaaaatagc tacaacagct actgttgcac
    50521 tcatgaaaaa aattgcccta aaaactgctt ctttgaaggc ttgttttgtc acatcttgtc
    50581 ctttctagtg aagaaagtaa gggagatacg acacctccct acttgccttc tttatcttat
    50641 tgtacgatga aacgtctgca tctctttaga gatttatgga gcaaacattt tatttaatct
    50701 tgtcccaggt ggttaatttg ccactaaaaa cgtctgcaag ttcagccata ctgacttggc
    50761 ttgccttatt gtcattattg accacaacag caataccgtc taaagcaata gcatcatggg
    50821 tgagactctt accttcttca ggagttaatt ccctagaaac cataccaata tcagcggttt
    50881 tctccttaac agcggtaata cctgctgaag acccattaga ggtaatatca atcgtaactt
    50941 ctggattttc ttttttataa gcttctgcta atttttccat taaagaagat actgaagtgg
    51001 aacctacaac agacaacttg cctgataagt gttggcttgt atattctgtg gtttcagttt
    51061 tagcttcaat aaatttatta tctgtgacca cttgttgacc ttgtttggag tggataaagc
    51121 tgataaaatc ttgacctagc ttggaaagat tagaagacca aacaatgttg aagggacgtt
    51181 gaagagggta ttcaccatct aaaactgtgt ctcgactagc cttgacacca tcaatctcta
    51241 aagccttgac agatttcgtt aaagatccca aggagatgta gccgatagca ttagcattcc
    51301 cttgaactgc tgagagaaca ccttctgtac tattttgaat cacagctgtt ttggcagtgt
    51361 tgtcaatttt tttatcaccg tcttttttga gaatccctgt gatttctgtg aaggcacccc
    51421 gtgttccaga gccattttct cgtgaaatca cctcaatcgt tcctgaagct gactgtttgg
    51481 aagcagctga ctgattgcca caggcaacaa gcccaaatcc tgataagcca atggctgcaa
    51541 gagtaagcat ttttttgaat ttcataataa tcacctttat ctctatgtat ttttcttgtg
    51601 taggcttact acatttatag tctaacaagt ctttgtaaag gtttatccct gattcatgta
    51661 aagattgtgt aaagaatcaa aaaaagccac ttttgaaaaa tggctgctcc taaaaatagc
    51721 tttaaaaatt attagtcctg tgcgaaagat tggttaggaa gaaaaatcgt gaagcaactg
    51781 cctctgccaa gctgactcgt caccgtgact tggccaccta ataattgact gagttctttg
    51841 acaatggcaa ggccaagacc agtgccacca gtttgtctgc ttcgaccttt attaactcgg
    51901 taaaaacgtt caaaaatacg atcctgctct aattgactaa taccaatccc tgtatctgat
    51961 acagaaatct taatgccttc gttcaccttt tgggtcttga cctcaatttt tcccccttgt
    52021 tcagtgtaac ggatggcatt ggataaaaga ttgagtaaga tttgggaaag taattgacta
    52081 tctgatacga gggtgacatc atctggcacc tgcaccttta gctgtaaatc cttcttcttg
    52141 agctgaggtt gcaagctttg agtcaaatct tgtacaaatt ctgccaaaga aagggtcgtc
    52201 cattgtatag gcatttgttg agccttagat aaggtaagaa gatgctcaac aatatgctca
    52261 agacgcaaac tttctttgta aataatgtct agaaagtcat ccttgagcgc ttcttcttca
    52321 gctgacatcc ccttaatggt ttcagcaaag cccttaatcg aagtaactgg tgtcctcaat
    52381 tcatgggagg catttgagac aaaggctaaa tttaactttt cataagttct aatcgttgtt
    52441 aaatcatata gcaagacgag cacagcttcc acagattggg tggggctaaa aacgggaact
    52501 gctgtcactt ctaaaatcaa gtcaccctca tgaaacccac ttacttcttg ttttaacctt
    52561 gttttttgat caaaggcttg gtgaactaaa ttccgaatat ccatccgttt gaggtcatca
    52621 agtgaactta tgtcgccgtc cacatcggga aaataatgag gcagagagcg actggataat
    52681 aacatctgac cttgagcgga aactaaaaac gtccccatgg ttaggtgcga cagaagaacc
    52741 tccattgttt cggctaggtc cttgtattgc tgatcctgtt gggagacttt ggtttttagg
    52801 ccagacacat actgagccaa agactttaag tcttcttgcc ctttttctaa aaagtattca
    52861 ctactggtca agagaggttg gtgcaaggtc tcaaaagcaa cttcccattt ccaaaggcaa
    52921 aagagccagt agccacctag tcccaaagaa agggctagaa gaaagagacc gatgccttta
    52981 ctgatccaag ttaatgccat ccctgcaatc agaatgaggc taacacttag attgactagc
    53041 caaaattgaa ggtagcgttt catctataac tccttgaact tataaccata accccgaatg
    53101 gttcgaataa attgaggggc tttaggattg tcttcaattt tttccctcaa cttaccaata
    53161 tgaacgtcca ccaaacgtgt ttcctgccca aagtcatacc cccagatacg ttccaaaaga
    53221 cgctctctag tcagtgtcat gttgggatgt ttcataagat agagcaagag ttcaaattct
    53281 tttggggtca aactcagtaa cttattcgcc ttgtagactt catgacgctc agggtatact
    53341 ttcaaggtcc caaatagcca agaatcgtca gcgatattat ctgaatcatc tccttcttgt
    53401 tctcctttag ttcgcctgag gacagccttg acacgcgcca gcaattctct agggctaaaa
    53461 ggcttggtca ggtagtcatc agcccctaat tccaaggcca aaaccttatc aaattcatca
    53521 cttttcgcag aaaccatcat aattggagtt ttgacgcctt tggctctcag ccgcttacaa
    53581 acttccatgc catctaattg tggtaacatg atatcaagca agataaaatc aaagggttct
    53641 gtttctgcca aagctaaggc cttccgtcca tttgttacca attgagtaga aaagccttcc
    53701 ttacttaaat ggtagtcaag taatttcaga atgtgttctt catcatccac taataagact
    53761 tgttttgtca tctattatct cctattggta acattataac acaattatca gaaatcctaa
    53821 cattgctaaa tcagattaaa tttgcttatc aagactagta tctggtcaaa cgctcaatca
    53881 tctccttgtg ctctggatag gtcgccagta gatctaccct ttcaaataat tcaaaatcct
    53941 caaattcaaa accaggagca acaagacaag aaaccagagc atcatcctta tcaactgttg
    54001 atccccaaat agtgccctta ggaacacagt agtgaagttg ttgccctttg gatatgtcca
    54061 ggcctaaagt gactacttcg tagtgaccat ctgctgtaat catgtgaaca gtaagtgggg
    54121 atcctgcatg aaaataccag atttcatctg ctgtcaatcg gtgaaaatgt gaaggattcg
    54181 tttcttctaa taagaaataa atactggtat aaagcgccct tcccttacca gcaaggttta
    54241 tagtgtctga agcttttttt gtttgtctaa aatagccacc ttcaacatgg ggagctaact
    54301 ctagagttct tatcaagtct tctttatcca tcggggccaa tgggttgaag taactcttgt
    54361 tcaaagtggt tttacgattt caagaactcc tctcagttct gaggacacgg taatgattga
    54421 tgcgacggaa gtaaaaatca atcgctctaa aaaaagaatt agcgaatgat tttggtaaaa
    54481 agaaatttca cgctatgaag gctcaagcga ttgtcacaag tcaagggaga attgtttctt
    54541 tggatatcgc tgtgaactat tgtcatgata tgaagttgtt caaaatgagt cgcagaaata
    54601 tcggacaagc tggaaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc
    54661 ctcaagcaca aactccacgt aaagccagca aactcaagcc gctaacagct gaagataaag
    54721 cctataacca tgcgctatcc aaggagagaa gcaaggttga gaacatcttt gccaaagtaa
    54781 aaacgtttaa aatattttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa
    54841 tgaatttgag tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta
    54901 ttatttggtt aggtgaatta gtgaagcgtt taggcaagtg tctctggtta cgacgtcatg
    54961 gcctctaaat cgattatatt taggggtcat gactagtgaa gcagttagct agttcgcata
    55021 taagcggcta gcgtctaaca attaggaact ttagttccaa taactttaag attacgacgt
    55081 tttaggacat aaatcgatca tatttatgtc ctaaaactag tgaagcgcct agccaaagtc
    55141 cgaataggat ttggcgttag ttacttagat tgctttgcaa tcaagtaact ttggcgattt
    55201 acatcttctc tggcgcttct actccaagca agcgaagggc ttctttgaga acgactgcgg
    55261 ttgcgtagct gagggctaga cggctgtcgc gttctgggct ttcatccaag atacgtgtat
    55321 gtgcatagta tttgttaaag gattgagcca ggctaattgc aaatttagca atgatagaag
    55381 gttcaaagtt atctgccgca cggttgataa tacgtgggaa gtcttgaatg agtttaatga
    55441 tttcccagct ttcagtatca ttcaagctat agttgccagc tgtttctggt ttgaaatcgg
    55501 ctttgcgtaa gatagattgg atacgagcgt aggcatattg aacgtaaggt ccagtttcac
    55561 cctcgaagga taccatagct tctaggtcga agtcgtatcc atttgtacgg tcagttttga
    55621 ggtcatagaa tttaatggct ccaaccccaa cagcatgtgc tacttggtct ttgttttcta
    55681 gttcaggatt tttagcctcg atttggacct tggcacggct aacagcctct gcaacagtag
    55741 gctctagcaa gatgacattc cctttacgag tagagagctt cttcccttct tttgtaacca
    55801 gaccaaaagg aacgtgggta atgtcgtcac tccaatcgta gcccatctct tgcaagacag
    55861 ctttgagttg tttaaagtgg gcagattgct cttgaccaac gacgtagata gatttagcaa
    55921 attggtattc atttttacgg tagagggctg cagccaagtc acgtgtgata tagagagttg
    55981 caccatcaga cttcttgatg agggctggat gttcaattcc atatttctca agattcacaa
    56041 cttgggcacc ttctgattca agaagtagtc ctttttcaga aagaatgtct acaactgcat
    56101 ccatcttatc attgtagaag gcttctccgt tatagctgtc aaattcaacc ttcaattcat
    56161 tgtaaaggcg gttaaattcc actaaacttt catcgcggaa ccattgccaa agagcgagag
    56221 cttcctcatc tccattttca agtttacgga accattcgcg cgcttcttca tccaagctag
    56281 ggtcattttc agcttcagcg ttgatgcgga catagagttt aaggagttca tcgattggat
    56341 gagcttttac agcttcttcg tcgccccatt ttttgtaggc aacaatcaac atcccaaatt
    56401 gtttacccca gtctcccaaa tggttgacct tgaccgtttg ataaccgatt ttttggaaaa
    56461 tatgtgacaa gctatctccg ataacagttg aacgcaggtg gccaatagaa aatggtttag
    56521 cgatattcgg actagacatg tcgataacaa cattttcttg tttgccaata ttttggtcag
    56581 catagtgttc tttttcagtg gtaacagctt gcaatacttg agcagaaatg gcagatttat
    56641 caaggaaaaa gttaacgtaa ggtcctgttg cgacaacttt ttcaaaggct tggctgttca
    56701 ttttttcagc cagttcagcc gcaatcattt gtggtgcttt acgttcgact ttggcaagag
    56761 aaaaagcagg gaaagcgatg tcacccattt ctgagttttt aggggtttcc agtaacttta
    56821 aaatagcctc ttggtccagg ctatcaatga tgctagccaa ttcgctagca atcaattctt
    56881 ttgtattcat taagagctcc tttttggact tttctactat tttaacacaa ttttaaagaa
    56941 agaagaaaaa atttttgaaa tctcctgttt ttttggtata atatggttat aaatatagtt
    57001 ataaatatgc acgcaagagg attttatgag aaaaagagat cgtcatcagt taataaaaaa
    57061 aatgattact gaggagaaat taagtacaca aaaagaaatt caagatcggt tggaggcgca
    57121 caatgtttgt gtgacgcaga caaccttgtc tcgtgatttg cgcgaaatcg gcttgaccaa
    57181 ggtcaagaaa aatgatatgg tgtattatgt actagtaaat gagacagaaa agattgattt
    57241 ggtggaattt ttgtctcatc atttagaagg tgttgcaaga gcagagttta ccttggtgct
    57301 tcataccaaa ttgggagaag cctctgtttt ggcaaatatt gtagatgtaa acaaggatga
    57361 atggatttta ggaacagttg ctggtgccaa taccttattg gttatttgtc gagatcagca
    57421 cgttgccaaa ctcatggaag atcgtttgct agatttgatg aaagataagt aaggtcttgg
    57481 gagttgctct caagacttat ttttgaaaag gagagacaga aaatggcgat agaaaagcta
    57541 tcacccggca tgcaacagta tgtggatatt aaaaagcaat atccagatgc ttttttgctc
    57601 tttcggatgg gtgattttta tgaattattt tatgaggatg cggtcaatgc tgcgcagatt
    57661 ctggaaattt ccttaacgag tcgcaacaag aatgccgaca atccgatccc tatggcgggt
    57721 gttccctatc attctgccca acagtatatc gatgtcttga ttgagcaggg ttataaggtg
    57781 gctatcgcag agcagatgga agatcctaaa caagcagttg gggttgttaa acgagaggtt
    57841 gttcaggtca ttacgccagg gacagtggtc gatagcagta agccggacag tcagaataat
    57901 tttttggttt ccatagactg cgaaggcaat caatttggcc tagcttatat ggatttggtg
    57961 acgggtgact tttatgtgac aggtcttttg gatttcacgc tggtttgtgg ggaaatccgt
    58021 aacctcaagg ctcgagaagt ggtgttgggt tatgacttgt ctgaggaaga agaacaaatc
    58081 ctcagccgcc agatgaatct ggtactctct tatgaaaaag aaagctttga agaccttcat
    58141 ttattggatt tgcgactggc aacggtggag caaacggcat ctagtaagct gctccagtat
    58201 gttcatcgga ctcagatgag ggaattgaac cacctcaaac ctgttatccg ctacgaaatt
    58261 aaggatttct tgcagatgga ttatgcgacc aaggctagtc tggatttggt tgagaatgct
    58321 cgctcaggta agaaacaagg cagtcttttc tggcttttgg atgaaaccaa aacggctatg
    58381 gggatgcgtc tcttgcgttc ttggattcat cgccccttga ttgataagga acgaatcgtc
    58441 caacgtcaag aagtagtgca ggtctttctc gaccatttct ttgagcgtag tgacttgaca
    58501 gacagtctca agggtgttta tgacattgag cgcttggcta gtcgtgtttc ttttggcaaa
    58561 accaatccaa aggatctctt gcagttggcg actaccttgt ctagtgtgcc acggattcgt
    58621 gcgattttag aagggatgga gcaacctact ctagcctatc tcatcgcaca actggatgca
    58681 atccctgagt tggagagttt gattagcgca gcgattgctc ctgaagctcc tcatgtgatt
    58741 acagatgggg gaattatccg gactggattt gatgagactt tagacaagta tcgttgcgtt
    58801 ctcagagaag ggactagctg gattgctgag attgaggcta aggagcgaga aaactctggt
    58861 atcagcacgc tcaagattga ctacaataaa aaggatggct actattttca tgtgaccaat
    58921 tcgcaactag gaaatgtgcc agcccacttt ttccgcaagg cgacgctgaa aaactcagaa
    58981 cgctttggaa ccgaagaatt agcccgtatc gagggagata tgcttgaggc gcgtgagaag
    59041 tcagccaacc tcgaatacga aatatttatg cgcattcgtg aagaggtcgg caagtacatc
    59101 cagcgtttac aagctctagc ccaaggaatt gcgacggttg atgtcttaca gagtctggcg
    59161 gttgtggctg aaacccagca tttgattcga cctgagtttg gtgacgattc acaaattgat
    59221 atccggaaag ggcgccatgc tgtcgttgaa aaggttatgg gggctcagac ctatattcca
    59281 aatacgattc agatggcaga agataccagt attcaactgg ttacagggcc aaacatgagt
    59341 gggaagtcta cctatatgcg tcagttagcc atgacggcgg ttatggccca gctgggttcc
    59401 tatgttcctg ctgaaagcgc ccatttaccg atttttgatg cgatttttac ccgtatcgga
    59461 gcagcagatg acttggtttc gggtcagtca acctttatgg tggagatgat ggaggccaat
    59521 aatgccattt cgcatgcgac caagaactct ctcattctct ttgatgaatt gggacgtgga
    59581 actgcaactt atgacgggat ggctcttgct cagtccatca tcgaatatat ccatgagcac
    59641 atcggagcta agaccctctt tgcgacccac taccatgagt tgactagtct ggagtctagt
    59701 ttacaacact tggtcaatgt ccacgtggca actttggagc aggatgggca ggtcaccttc
    59761 cttcacaaga ttgaaccggg accagctgat aaatcctacg gtatccatgt tgccaagatt
    59821 gctggcttgc cagcagacct tttagcaagg gcggataaga ttttgactca gctagagaat
    59881 caaggaacag agagtcctcc tcccatgaga caaactagtg ctgtcactga acagatttca
    59941 ctctttgata gggcagaaga gcatcctatc ctagcagaat tagctaaact ggatttgtat
    60001 aatatgacac ctatgcaggt tatgaatgtc ttagtagagt taaaacagaa actataaaac
    60061 caagactcac tagttaatct agctgtatca aggagacttc tttgacaatt ctccactttt
    60121 ttgctagaat aacatcacac aaacagaatg aaaaggagct gacgcattgt cgctcccttt
    60181 tgtctatttt ttaaggagaa agtatgctga ttcagaaaat aaaaacctac aagtggcagg
    60241 ccttggcttc gctcctgatg acaggcttga tggttgctag ttcacttctg caaccgcgtt
    60301 atctgcagga agtattagac gccctcctta ctgggaaata tgaagctatt tatagtatcg
    60361 gggcttggtt gattggtgtg gccgtagtcg gtctagttgc tggtggactc aatgttgtcc
    60421 tcgcagccta tattgcccaa ggagtttcat ccgaccttcg ggaggatgcc ttccgtaaaa
    60481 ttcaaacctt ttcttatgct gatattgaac aatttaatgc gggaaatcta gtcgttcgaa
    60541 tgacaaatga tatcaaccag attcagaacg ttgtcatgat gaccttccaa attcttttca
    60601 gacttcccct cttgttcatc ggttcgttta tcctagcggt tcaaacctta ccttctctgt
    60661 ggtgggtgat tgttctcatg gtagtcttga tttttggttt gactgctgtc atgatgggaa
    60721 tgatggggcc tcgttttgcc aagtttcaaa cccttcttga gcgcatcaat gccattgcca
    60781 aggaaaattt acgtggcgtt cgtgtggtca agtcctttgt ccaagaaaaa gagcaatttg
    60841 ctaagtttac agaggtctca gacgagcttt ttggtcaaaa cctttacatt ggttatgcct
    60901 tttcagtagt ggaacccttt atgatgttgg ttggttacgg ggcggtcttc ctctctattt
    60961 ggctggtcgc gggaatggtt cagtcggatc cgtctgttgt tggttccatc gcttcttttg
    61021 ttaattacct aagccagatt atctttacca ttgttatggt tggatttttg ggaaattctg
    61081 tcagccgtgc catgatttcc atgcgtcgta ttcgagaaat tcttgacgca gagccagcta
    61141 tgaccttcaa ggatatccca gatgaagagt tggttggaag ccttagcttt gaaaatgtga
    61201 cctttaccta tccaatggac aaggaaccga tgctgaaaga tgtgagcttt actattgaac
    61261 ctggtcaaat ggttggtgta gttggagcga cgggtgcagg aaagtcaacc ttggctcaat
    61321 tgattccacg tctctttgat ccacagaacg gggccattaa aatcggtggc aaggatattc
    61381 gagaagtgag tgaaggaacc ctgcgtaaaa cagtttccat cgttctccaa cgtgccattc
    61441 tttttagtgg aacgattgca gataacttga gacaggggaa gggaaatgct actctatttg
    61501 aaatggagcg cgcagccaat attgcccagg ctagtgaatt cattcatcgt atggagaaaa
    61561 cctttgaaag tccagttgaa gaacggggaa ccaatttctc tggtggacaa aaacaaagga
    61621 tgtcgattgc gcgtgggatt gtcagcaatc cacgtattct gatttttgac gattcgacct
    61681 cagccttgga tgccaaatca gagcgcttgg tgcaagaagc tttgaataag gacttgaagg
    61741 ggacgacaac cattattatt gctcaaaaaa ttagctcggt tgtccatgca gacaagatct
    61801 tggttctaaa tcaaggacga ttgattggtc aaggcacgca tgcagacttg gttgccaaca
    61861 atgccgttta ccgtgaaatc tatgaaacac agaaatgaaa gacaaactat aagaaaagtc
    61921 aatagtttta tctaaattat ttcttatttc aatttgatga tttggcgatg attttagagc
    61981 acggcaaaaa gcccttgaaa aagtccattt tttcaaaggt aatcctgtgt taatttcaga
    62041 aattacatca ctttttgttc gtcaaatggc agctcttttt taggatataa aacagggttc
    62101 ggataagttt ttttgcaagg tggatgatgg ctacattgta atgttttcct tgttctaatt
    62161 tagtcttaag ataggcctta aaagcaggcg aaaagcgagg gcatgctttg gcagcttgta
    62221 tgagtaccta ccgcagatga ggggaacccc gtttgaccat tcttccagct aaatcaatct
    62281 gacctgactg ataaatagaa gaatccagtc cagcgaaagc ttgtaattga gcaggattat
    62341 caaaggcatg aatattttga atctcggcta aaatgaccgc ccctaaacga ttcccaatcc
    62401 cagtaaccgt cgtgatgacc gagttgaact cagccatcaa gtcattgaca catgtttccg
    62461 ccttgtcaat gagcctcttg taatgtttga tgttttcatt acacgagata aaacgtttat
    62521 gcgttatcaa actcatgacc aattgaaaca aaaagctgtg gttagatcct ttcggaaatt
    62581 gtcaagcgat tggaggaaat gaactaatcc acagcggctt attccaagta taccacttgg
    62641 gctttggcag tagctaactg cgctaaatat aatataagga ggagtaaaat gaagacagtt
    62701 caattttttt ggcattattt taaggtctac aagttctcat ttgtagttgt catcctgatg
    62761 attgttctgg cgacttttgc ccaagccctc tttccagtct tttctggaca agcggtgacg
    62821 cagctagcca atttagttca agcttatcaa aatggcaatc cagaacttgt atggcaaagc
    62881 ctatcaggaa tcatggtcaa tcttggcctg ctggttttgg ttctatttat ctctagtgta
    62941 atatacatgt gtctcatgac gcgcgtgatt gcagaatcga ccaacgagat gcgcaaaggc
    63001 ctctttggta agcttgctca gttgacggtt tctttctttg accgtcgaca agatggcgat
    63061 atcctgtctc attttaccag tgatttggat aatatcctac aagcctttaa cgaaagcttg
    63121 attcaggtca tgagcaatat tgttttatac attggtctga ttcttgtcat gttttcgaga
    63181 aatgtgacgc tggctctcat caccattgcc agcaccccat tggctttcct tatgctgatt
    63241 ttcatcgtga aaatggcacg caaatacacc aacctccagc agaaagaggt agggaagctc
    63301 aacgcctata tggatgagag catctcaggc caaaaagccg tgattgtgca aggaattcaa
    63361 gaggatatga tggcaggatt tcttgaacaa aatgagcgcg tgcgcaaggc aacctttaaa
    63421 ggaagaatgt tctcaggaat tcttttccct gtcatgaatg ggatgagcct gattaataca
    63481 gccatcgtca tctttgctgg ttcggctgta cttttgaatg ataagtctat tgaaacaagt
    63541 acagccctag gtttgattgt tatgtttgca caattttcac agcagtacta ccagcctatt
    63601 atccaagttg cagcgagttg gggaagcctt cagttggcct ttactggagc tgaacgaatt
    63661 caggaaatgt ttgatgcaga ggaggaaatc cgacctgaaa aggctccaac cttcactaag
    63721 ttgcaagaaa gtgttgaaat cagtcatatc gatttttcat acttgcctga taaacctatt
    63781 ttgaaagatg tcagcatttc tgcccctaaa ggccagatga cagcagttgt tgggccgaca
    63841 ggttcaggaa aaacgactat tatgaacctc atcaatcgct tttatgatgt tgatgctggt
    63901 ggtatttatt ttgatggtaa agacattcgt ggctatgact tagatagtct tagaagcaag
    63961 gtgggaattg tattgcaaga ttcggtcttg tttagcggaa cgattagaga caatatccga
    64021 tttggtgtgc cagatgctag tcaggaaatg gttgaggtag cagcaaaagc aacccacatt
    64081 cacgactata tcgaaagttt gcctgataag tacgatactc ttattgatga tgaccagagc
    64141 atcttttcaa cagggcagaa gcaattgatt tcaatcgctc gaaccctgat gacagatcca
    64201 gaaattctca ttctcgatga agcaacttca aacgtagata cggtgacaga aagcaagatt
    64261 cagcatgcca tggaggtggt tgtagcaggt agaactagtt tcgtcattgc ccaccgcttg
    64321 aaaaccattc tcaatgcaga tcagattatt gtccttaaag atggagaagt cattgaacgt
    64381 ggtaaccacc atgaactttt gaagctaggt ggcttttatt cagaactcta tcacaatcaa
    64441 tttgttttcg aatgagaaag aagttgtcct atgtgggcag ctttttcttg tccataaaaa
    64501 atgtttatca cagccttaaa aaaaacatat tagacgaaag tcattttgag tgatatgata
    64561 ggattatcgt tagcattcga aaggagaggc atcatggcta gaacggttgt aggagttgct
    64621 gcaaatctat gtcccgtaga cgcagaaggc aaaatcattc attcatctgt atcttgtaga
    64681 ttcgcagaga tcattcgtca agtcggtggt ctccctttag tcattcctgt tggtgatgag
    64741 tcagttgtac gtgattatgt ggaaatgatt gacaaactca ttttgacagg aggccaaaat
    64801 gttcatcctc agttttatgg agagaaaaag accgtcgaga gcgatgatta caatctggtc
    64861 cgtgacgaat ttgaattggc actcttgaag gaagcgcttc gtcagaataa accaattatg
    64921 gcaatctgtc gcggtgtcca acttgtcaat gttgcctttg gtggaaccct caatcaagaa
    64981 atcgaaggtc actggcaagg actacctttc gggacatctc actctattga gacagtagaa
    65041 ggaagcgtgg tggctaagct atttgggaaa gaaagtcagg tcaactcagt tcatcgtcaa
    65101 agcattaaag atttggcacc taatttccgt gtaactgcta ttgattcaag agaccaaact
    65161 attgaagcga ttgagtctat cgacgagcac cgcattatcg gtttacagtg gcatccagag
    65221 tttctggtta atgaagaaga tggcaattta gaattatttg agtatttatt gaatgaactg
    65281 taacgattgg aacatctggt cgttctttct tttatttttt caaaattttt agaatgtggc
    65341 attttacgca aacgtttgaa ttctgataaa aattggagaa attcgacaaa aaaacttgaa
    65401 aaaaacgaag gtaagcgtta tgatagaaaa gaagaaatat tggaggaaga acatgtcaca
    65461 tattaaattt gattattcaa aagttttaga caaatttgtt gcaccacatg aagtggaata
    65521 catgcaatca caagtaacag cagcagatga attgatccgt aaaggaactg gtgctggtag
    65581 cgacttcttg ggatggttgg accttcctga aaaatacgac cgcgaagaat ttgaccgcat
    65641 cttgaaagct gctgagcaaa tcaagtcaga cagcgatgtt ttggttgtga tcggtattgg
    65701 tggatcttac cttggtgcaa aagcagcaat cgacttcttg aatcaccatt ttgctaactt
    65761 gcaaacaaaa gaagaacgca aagctccaca aatcctttac gcaggaaact caatctcatc
    65821 tacttacctt gctgacttgg tagagtatgt tgcagacaaa gacttctcag taaacgtaat
    65881 ttctaaatca ggtacaacaa ctgaaccagc gattgctttc cgtgtcttta aagaactctt
    65941 ggttaagaaa tacggtcaag aagaagctaa caaacgtatc tatgcaacaa ctgaccgcca
    66001 aaagggtgct gttaaggttg aagcagacgc taacggttgg ggaacatttg ttgttccaga
    66061 tgatatcggt ggacgcttct cagtattgac agccgttggt ttgcttccaa tcgcagcatc
    66121 aggagctgac ataaaagctc ttatggaagg tgcgaatgca gctcgcaaag actacacttc
    66181 agacaaaatc tctgaaaacg aagcttacca atacgcagct gttcgtaaca tcctttatcg
    66241 taaaggctat gcaactgaga tcttggtaaa ctatgagcca tcacttcaat acttctcaga
    66301 atggtggaaa caattggctg gtgaatcaga aggaaaagac caaaaaggta tctacccaac
    66361 ttcagccaac ttctcaactg acttgcactc acttggtcaa tttatccaag aaggaactcg
    66421 tatcatgttt gaaacagttg tccgtgttga caaacctcgt aaaaacgtgc ttattcctac
    66481 tttggaagaa gaccttgacg gacttggtta ccttcaagga aaagacgttg actttgtaaa
    66541 caaaaaagca actgacggtg ttcttcttgc ccacacagat ggtgatgtac caaacatgta
    66601 tgtgactctt ccagagcaag acgctttcac tcttggttac actatctact tcttcgaatt
    66661 ggcaattgcc ctttcaggtt acttgaatgc tatcaaccca tttgaccaac caggtgttga
    66721 agcttataaa cgtaacatgt ttgcccttct tggaaaacca ggatttgaag aattgagcaa
    66781 agaacttaac gcacgtctat aatagaagaa aagagtggtt tgcccactct ttttactctc
    66841 tttatccata gaaattggac tcagccaaga cttgtgatat aattatagaa agcaaaaagg
    66901 cagacgccta gataatagga gaaactatgt caaaagatat ccgcgtacgt tacgcaccaa
    66961 gtccaacagg actactacac atcggaaatg ctcgtacagc attgtttaat tacttgtatg
    67021 cgcgccatca tggtggaaca tttctcatcc gtatcgaaga tactgaccgt aaacgccatg
    67081 tcgaggatgg tgaacgttca caacttgaaa accttcgctg gttaggcatg gattgggatg
    67141 aaagtccaga atcacatgag aattatcgcc agtctgagcg tttggacttg tatcaaaaat
    67201 atattgacca actattagct gaaggaaaag cctataaatc ttacgttaca gaagaagagt
    67261 tggcagctga acgcgaacgc caagaagtag ctggcgaaac accacgctac atcaatgaat
    67321 accttggtat gagtgaagaa gaaaaagcag cttacatcgc agaacgtgaa gcagcaggga
    67381 tcatcccaac tgttcgtttg gctgtcaatg agtcaggtat ctacaagtgg catgatatgg
    67441 tcaaaggcga tatcgaattt gaaggtggca atatcggtgg tgactgggtt atccaaaaga
    67501 aagacggtta cccaacttac aactttgccg ttgttatcga tgaccacgat atgcaaatct
    67561 ctcatgttat ccgtggagat gaccatattg ctaatacacc aaaacagctt atggtctatg
    67621 aagctcttgg ttgggaagct ccagagttcg gtcacatgac cttgattatc aactctgaga
    67681 ctggtaagaa gttatctaaa cgtgatacta atacacttca atttatcgaa gattaccgaa
    67741 agaaaggtta ccttccagaa gcagtcttta actttattgc tcttcttggt tggaacccag
    67801 gtggtgaaga tgagattttc tctcgtgaag aattcattaa actttttgat gaaaaccgcc
    67861 tcagcaagtc accagcagcc tttgatcaga aaaaactaga ctggatgagc aatgattata
    67921 tcaagaatgc agaccttgaa accatctttg aaatggcaaa accattctta gaggaagcag
    67981 gccgtttgac tgacaaggct gaaaaattag ttgagctcta taaaccacaa atgaaatcag
    68041 tagatgagat tatcccattg acagatcttt tcttctcaga tttcccagaa ttgacagaag
    68101 cagagcgcga agtcatgacg ggtgaaacag ttccaacagt tcttgaagca ttcaaagcaa
    68161 aacttgaagc gatgacagat gatgaatttg tgacagaaaa tatcttccca caaattaaag
    68221 cagtccaaaa agaaacaggt attaaaggga aaaatctttt catgcctatt cgtatcgcag
    68281 tttcaggcga aatgcatggg ccagaattac cagatacaat tttcttgctt ggacgtgaaa
    68341 aatcaattca gcatatcgaa aacatgctaa aagaaatctc taaataaaga ggatacaata
    68401 atggacatct gggaaaagat gtacgaagaa gcacagaaac tatacaatcc acatgaagta
    68461 tcagactttg tttatgccaa tcatgttgta gctgcagtag aagcaggaga tggacaaata
    68521 tttacaggat tctgtatgga gggaacctgt ggtgttttcc atctctgcgc agaacgggcg
    68581 gccctcttca atatgtacca attttcagga caaactaagg ttaagaaagt attagccttt
    68641 cgagacaaac caccttatgg tggaagttca gccatgcctt gcggtgcttg tagagaattc
    68701 cttttagagc ttaatgctga aaataaagat gcagaattca tgatggacta taatataaga
    68761 aaaacagtta aagtcgcaga actaatccct tattggtggg gaaaagaacg tgcttctaag
    68821 tttaatgagc gatagaagag tcagtataat tctggctttt tttactataa gtt
//
LOCUS       DAVLZS010000005        67665 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLZS010000005 DAVLZS010000000
VERSION     DAVLZS010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67665
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.005"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(141..1076)
                     /locus_tag="VYO88_000289"
     CDS             complement(141..1076)
                     /locus_tag="VYO88_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1718459.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEINSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1073..1933)
                     /locus_tag="VYO88_000290"
     CDS             complement(1073..1933)
                     /locus_tag="VYO88_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1718460.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIS
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYS
                     QYQLVRKATL"
     gene            2041..4203
                     /locus_tag="VYO88_000291"
     CDS             2041..4203
                     /locus_tag="VYO88_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1718461.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     ELQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            4238..5497
                     /locus_tag="VYO88_000292"
     CDS             4238..5497
                     /locus_tag="VYO88_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1718462.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDTIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMPRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5511..6377
                     /locus_tag="VYO88_000293"
     CDS             5511..6377
                     /locus_tag="VYO88_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1718463.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6391..7224
                     /locus_tag="VYO88_000294"
     CDS             6391..7224
                     /locus_tag="VYO88_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1718464.1"
                     /translation="MKQDERKALIGKYTLLILGTVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7535..8977
                     /gene="gtfA"
                     /locus_tag="VYO88_000295"
     CDS             7535..8977
                     /gene="gtfA"
                     /locus_tag="VYO88_000295"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1718465.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9115..10308
                     /locus_tag="VYO88_000296"
     CDS             9115..10308
                     /locus_tag="VYO88_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1718466.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMNSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            10993..12972
                     /locus_tag="VYO88_000297"
     CDS             10993..12972
                     /locus_tag="VYO88_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1718467.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13039..14535
                     /locus_tag="VYO88_000298"
     CDS             13039..14535
                     /locus_tag="VYO88_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1718468.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14535..15461
                     /locus_tag="VYO88_000299"
     CDS             14535..15461
                     /locus_tag="VYO88_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1718469.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15470..16537
                     /locus_tag="VYO88_000300"
     CDS             15470..16537
                     /locus_tag="VYO88_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718470.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16548..17474
                     /locus_tag="VYO88_000301"
     CDS             16548..17474
                     /locus_tag="VYO88_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718471.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18042..18902
                     /locus_tag="VYO88_000302"
     CDS             18042..18902
                     /locus_tag="VYO88_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1718472.1"
                     /translation="MSQFITHQSLDATREGFVDELAKQGYVEGENIEIDLQNAQGEQR
                     NLKTISQQLAESSDVVLAIARPSAQSLANTTQTTPVIFSAVTAPVSAKLVESREHPGG
                     NVTGTSDQSSDAISTQVNLIKKVLPKAKTIGILYTQSEPNSVVQKDEDKRLLKEKGFT
                     VVEKTILDSNNVKAAAENLMAEVDMVFVPTDNIISSTMETVKQVSIKHKVPVFGGSTE
                     MIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENIAVELPEKLELHTNQEMADALG
                     IDISKLEGKE"
     gene            18914..19803
                     /locus_tag="VYO88_000303"
                     /pseudo
     CDS             18914..19803
                     /locus_tag="VYO88_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            19816..20619
                     /locus_tag="VYO88_000304"
     CDS             19816..20619
                     /locus_tag="VYO88_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1718473.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASSLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(20652..21362)
                     /gene="treR"
                     /locus_tag="VYO88_000305"
     CDS             complement(20652..21362)
                     /gene="treR"
                     /locus_tag="VYO88_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1718474.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21547..23514
                     /gene="treP"
                     /locus_tag="VYO88_000306"
     CDS             21547..23514
                     /gene="treP"
                     /locus_tag="VYO88_000306"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1718475.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLRDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            23692..25317
                     /gene="treC"
                     /locus_tag="VYO88_000307"
     CDS             23692..25317
                     /gene="treC"
                     /locus_tag="VYO88_000307"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1718476.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25573..25821
                     /locus_tag="VYO88_000308"
     CDS             25573..25821
                     /locus_tag="VYO88_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1718477.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26028..26822
                     /gene="racE"
                     /locus_tag="VYO88_000309"
     CDS             26028..26822
                     /gene="racE"
                     /locus_tag="VYO88_000309"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1718478.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            26819..27790
                     /locus_tag="VYO88_000310"
     CDS             26819..27790
                     /locus_tag="VYO88_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1718479.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27766..28287
                     /locus_tag="VYO88_000311"
     CDS             27766..28287
                     /locus_tag="VYO88_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1718480.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28284..28745
                     /locus_tag="VYO88_000312"
     CDS             28284..28745
                     /locus_tag="VYO88_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1718481.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28736..29476
                     /gene="xerD"
                     /locus_tag="VYO88_000313"
     CDS             28736..29476
                     /gene="xerD"
                     /locus_tag="VYO88_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1718482.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29476..30210
                     /locus_tag="VYO88_000314"
     CDS             29476..30210
                     /locus_tag="VYO88_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1718483.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQSST"
     gene            30223..30792
                     /locus_tag="VYO88_000315"
     CDS             30223..30792
                     /locus_tag="VYO88_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1718484.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            30779..31501
                     /locus_tag="VYO88_000316"
     CDS             30779..31501
                     /locus_tag="VYO88_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1718485.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31501..31743
                     /gene="yidD"
                     /locus_tag="VYO88_000317"
     CDS             31501..31743
                     /gene="yidD"
                     /locus_tag="VYO88_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1718486.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(31968..32933)
                     /locus_tag="VYO88_000318"
     CDS             complement(31968..32933)
                     /locus_tag="VYO88_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1718487.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLAEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33029..33781)
                     /locus_tag="VYO88_000319"
     CDS             complement(33029..33781)
                     /locus_tag="VYO88_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1718488.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINIASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(33778..34734)
                     /locus_tag="VYO88_000320"
     CDS             complement(33778..34734)
                     /locus_tag="VYO88_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1718489.1"
                     /translation="MQTKSKHTKLFWILIILTIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(34724..35683)
                     /locus_tag="VYO88_000321"
     CDS             complement(34724..35683)
                     /locus_tag="VYO88_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1718490.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36106..36808)
                     /gene="galE"
                     /locus_tag="VYO88_000322"
                     /pseudo
     CDS             complement(36106..36808)
                     /gene="galE"
                     /locus_tag="VYO88_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
     gene            37209..38273
                     /gene="pepA"
                     /locus_tag="VYO88_000323"
     CDS             37209..38273
                     /gene="pepA"
                     /locus_tag="VYO88_000323"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1718491.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38295..38591
                     /locus_tag="VYO88_000324"
     CDS             38295..38591
                     /locus_tag="VYO88_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1718492.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39273..39716
                     /locus_tag="VYO88_000325"
     CDS             39273..39716
                     /locus_tag="VYO88_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1718493.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            39720..40484
                     /locus_tag="VYO88_000326"
     CDS             39720..40484
                     /locus_tag="VYO88_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV1718494.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAVFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40499..41227
                     /locus_tag="VYO88_000327"
     CDS             40499..41227
                     /locus_tag="VYO88_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718495.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            41220..42740
                     /locus_tag="VYO88_000328"
     CDS             41220..42740
                     /locus_tag="VYO88_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1718496.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTV
                     LLGLSYSPALLVQKEKENVIIAGKIGPEPEILANMYKLLIEENTSLTATVKPNFGKTT
                     FLYEALKSGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVSTLEPALRYQAIQSGEIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43085..43891
                     /locus_tag="VYO88_000329"
     CDS             43085..43891
                     /locus_tag="VYO88_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1718497.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(44057..44593)
                     /locus_tag="VYO88_000330"
     CDS             complement(44057..44593)
                     /locus_tag="VYO88_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1718498.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            44726..45616
                     /locus_tag="VYO88_000331"
     CDS             44726..45616
                     /locus_tag="VYO88_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1718499.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILNLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            45860..46213
                     /locus_tag="VYO88_000332"
     CDS             45860..46213
                     /locus_tag="VYO88_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1718500.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            46214..47251
                     /locus_tag="VYO88_000333"
     CDS             46214..47251
                     /locus_tag="VYO88_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1718501.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAAFECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(47298..48305)
                     /gene="galR"
                     /locus_tag="VYO88_000334"
     CDS             complement(47298..48305)
                     /gene="galR"
                     /locus_tag="VYO88_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1718502.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGINLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            48469..49647
                     /locus_tag="VYO88_000335"
     CDS             48469..49647
                     /locus_tag="VYO88_000335"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1718503.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKREDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            49666..51147
                     /locus_tag="VYO88_000336"
     CDS             49666..51147
                     /locus_tag="VYO88_000336"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1718504.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            51217..51621
                     /locus_tag="VYO88_000337"
     CDS             51217..51621
                     /locus_tag="VYO88_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1718505.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDIANQEGKNVCKATFTMFVTGQRSEDRQVRI"
     gene            51802..52566
                     /locus_tag="VYO88_000338"
     CDS             51802..52566
                     /locus_tag="VYO88_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEV1718506.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            52563..53024
                     /locus_tag="VYO88_000339"
     CDS             52563..53024
                     /locus_tag="VYO88_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV1718507.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(53075..54337)
                     /locus_tag="VYO88_000340"
     CDS             complement(53075..54337)
                     /locus_tag="VYO88_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1718508.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(54337..54918)
                     /locus_tag="VYO88_000341"
     CDS             complement(54337..54918)
                     /locus_tag="VYO88_000341"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1718509.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITNVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(55318..55413)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(55796..56035)
                     /locus_tag="VYO88_000342"
     CDS             complement(55796..56035)
                     /locus_tag="VYO88_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1718510.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(56080..56178)
                     /locus_tag="VYO88_000343"
     CDS             complement(56080..56178)
                     /locus_tag="VYO88_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1718511.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            complement(56190..57017)
                     /gene="xth"
                     /locus_tag="VYO88_000344"
     CDS             complement(56190..57017)
                     /gene="xth"
                     /locus_tag="VYO88_000344"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1718512.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            57151..57606
                     /locus_tag="VYO88_000345"
                     /pseudo
     CDS             57151..57606
                     /locus_tag="VYO88_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            57603..58133
                     /locus_tag="VYO88_000346"
     CDS             57603..58133
                     /locus_tag="VYO88_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1718513.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            58261..60006
                     /locus_tag="VYO88_000347"
     CDS             58261..60006
                     /locus_tag="VYO88_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718514.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            59996..61747
                     /locus_tag="VYO88_000348"
     CDS             59996..61747
                     /locus_tag="VYO88_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718515.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVMQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            61920..62612
                     /locus_tag="VYO88_000349"
     CDS             61920..62612
                     /locus_tag="VYO88_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1718516.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            62655..63881
                     /locus_tag="VYO88_000350"
     CDS             62655..63881
                     /locus_tag="VYO88_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1718517.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            65046..67172
                     /gene="pfbA"
                     /locus_tag="VYO88_000351"
     CDS             65046..67172
                     /gene="pfbA"
                     /locus_tag="VYO88_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV1718518.1"
                     /translation="MKYFVPNEVFSIRKLRVGTCSVLLAISILGSQGILSDEVVTSSS
                     PMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNSISSNGTIRSNS
                     QLDNRTVESTVTSTNKNKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAI
                     QDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKGHTHLELNEKATILNGINIKNHPSIV
                     FMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNS
                     NNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEP
                     LTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKIL
                     NNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLL
                     DLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNI
                     ELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYISFIKSNANGKE
                     PVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNGEFNS
                     SKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKI
                     MELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            67156..67452
                     /locus_tag="VYO88_000352"
     CDS             67156..67452
                     /locus_tag="VYO88_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718519.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYKLTEYSKMK"
BASE COUNT        19910 a        12432 c        15115 g        20208 t
ORIGIN      
        1 aaaaataggc tccataatat ctatagggga tttacccact acaaatatta tagagacaat
       61 aaaacttcag atccgtaaaa cttaattgaa ttactaatct gaagttattt ttatatcgtt
      121 tatattataa ttgtgttatt ttacttccaa ctattgagag aaatttcgcc actatttagc
      181 cagatttctt ttccgttatc acattgaact aaaagttttc cattttctga gatgtcttta
      241 gcaagtccct tgtagtcttt ttgctctagt gtgaaagtga cttcttttcc tagaatgaat
      301 gactgttttt tgtataggta taatagctct tctgctggtg tttcgaagaa agcacgccag
      361 atttctatga tcaattcatt ccttgttata ggagctgtag ctttaaataa gctggcagct
      421 ttttctttta attcctgagg gaagtcttta atagtgaaat tgatacctac tccaataatg
      481 atatctgtga ctaagccagt ttctacagag gtcattgctt cagtaaggat tcctccaatt
      541 ttatgattgt ttagatagat atcattgacc cattttatat cgacatctat taaagttagg
      601 ttcttaatgg ctttgtagac agctccagct acaagtagtg tgtaggatgg taatttgtca
      661 taggggagat ttggtttaag atggagtgtc atataaattc caccttgtgg tgagtagaag
      721 gaacgttgaa aacggcctcg gcctgctgtt tgataggaag ctagatagag agtatttgct
      781 tcatggccta aatcaattgc ttcttttgca tctagttgtg ttgattttgt ttcgggttta
      841 aagctgactt taattggaag attttcttct agaatctctg gaagaataag gtcaccattc
      901 attagtttat atcctctatt tttgatacta ttaatttcaa tgccttcttg ttctagtcgc
      961 ttgatagctt tccaaattga tgttcggctt agggatagtt tttctgcgat tttttctccg
     1021 ctgatatagt cggtttcttt agataggatt tggtagacag cttggtagga tttcataatg
     1081 ttgcctttct cactagttgg tattgagagt attcttttct tgtatgactt ggagactgat
     1141 taaagtattg tttataagct ttcgaaaaat ggagtggatc tgaaaaacct accgagtatg
     1201 caattacctt gatggactct tgggtatttt cgagaagttg tctagctcgg tgcattcgaa
     1261 cgtagagtag gtattctttg ggtgataagg tattaaattc tttgaatacg cttgataagt
     1321 agcttctgtg aacggatagt tcttttgcta aatcttgaat tgtaagtgat tgaggatagt
     1381 ggctatcaat taatcgtttg cattcaagat agagttggtg ggttgatgaa atattctttt
     1441 ttttctgatt gggagcaata gttcccagat gaaacatcag ttcatgaagt tgtcccatga
     1501 tatggagttg agctaattca cttgattttg taatctgagc gaagcggaca atgtctgaga
     1561 tgagttttgc agtagtctgg gtatgacaag tttcagattg gatgagatag gattgatcag
     1621 aaatttgaga aagagcaaaa taatcagggg atttccctcc agtgattcct aaccagtagt
     1681 aggcccaagg ttctttacta tctgcttgat aaaaggttag ttcctctggt tttaatagaa
     1741 agaaatctcc ttcttttaaa tcaacaattt tacccttgta atgaaatttt ccttgtcctt
     1801 tactaatgta atgtaggacg tatgtatcac gaatggctgg accaaaagag taattaggtg
     1861 tgcattcctc atatccataa aagcttaggg caaggtcaat tgttccagtc tggtattctg
     1921 aaaaaactag catgtgctac ctcctaccta acattttacc atattcttga gacatttttc
     1981 tattttggaa agcgatttca ggtgataaaa tataatcaat aaagtgatga ggtgaagtaa
     2041 atgggagtta ggatagagaa taatctattt tatgttgaga gtaaaaatct aagtttgatt
     2101 attgaaaatc gaaatggcta cttacttttg aaacatttag gaaagactat taagaactat
     2161 aaaggttcca atagtgttta tgaacgagac catgcctttt caggaaatcc aacggctact
     2221 aatcgaacct ttagtttaga tactcagcga cagatttttg gacaacatgg cttaggagat
     2281 tttaggaaac caaccataca ggttcagcat agtgtaactg aagtaacaga ctttcgattt
     2341 gtagaagcaa agattttaaa aggtcagaat ggtccacagg gcttaccttc tccacatagc
     2401 atggacgata cagagactct tgtcttaatg ttagaagatt ctaaggctca acttagtctg
     2461 actttgtatt atactacttt taataatgat gcgactattg ctagctacag taaattagat
     2521 aataatagta atcaggaagt tgtcatccat aaagattttt cttttatggc tgattttcca
     2581 gctgcagatt acgaaatagt aactctgcag ggtgcttatg ctcgtgaaaa gactgttaga
     2641 cgtcaacagg tagaacaagg aatcttttcg attagctcaa accgaggtgc ttctggtcat
     2701 gctcaaacac cagctcttct actatgcgaa caaggagtca cagaggatgc tgggaatgtg
     2761 tttgctattc aactaatgta tagtggcaac tttgaagctt ttgttcaaaa aaatcaattg
     2821 aatgaagttc gggtggctat tggcattaat ccagaaaact tttcttggaa gttagcccct
     2881 gaggaatact ttgaaacacc ggtagcttta gtgactcatt cagatcaggg attaactggt
     2941 attagtcatg aaagtcagaa ttttgtactg aagcacatta ttctaagtga attttctaaa
     3001 aaagaacgtc caattctaat caataactgg gaagctactt actttgactt tcagagagaa
     3061 aaactgttag agttagcaga tgaagctaag aaagttggca ttgaactttt tgtattagat
     3121 gatggttggt ttggcaatcg ttttgatgat aatcgtgctt taggtgattg ggttgttaat
     3181 gaggaaaaac tgggtggaag tctagaaagt ctgatttcag ctatccatga aagaggtttg
     3241 cagtttggac tttggttaga acccgaaatg atttctgtag atagtgattt gtatcgtcaa
     3301 catcctgact gggctattca ggttcctgat tatgagcata cttattctcg gaatcaatta
     3361 gtacttaatc ttgccaatcc tcaggtagta gaatacttga aaagtgtctt agatcaactc
     3421 ctatcttatc atgagattga ttacattaaa tgggatatga accgcaatat cactaagcta
     3481 gggaatggat taacttatct agagacacag atgcaatctc atcagtacat gctgggactt
     3541 tacgaactcg tttcttatct gacagagaag cacagccata ttctctttga gtcctgctct
     3601 ggtggtggtg gacgaaatga tcttggtatg atgcgctatt tcccacaagt ctgggctagt
     3661 gataatactg atgccattgc acgtttacca attcaatacg gttcatccta tctctatcca
     3721 accatttcta tgggggctca tgtgtcagca gtaccgaatc atcagatggg acgaatgaca
     3781 ccattagaaa cacgtggcca tgtagcaatg atgggaaatt tgggctatga gcttgatttg
     3841 acaaatttat cagatgaaga gaaagctacg attgctaatc aggtgaactt gtataaagaa
     3901 ttacgaccag tagttcagtt aggacagcag tatagactaa ttaatcctga tactgcatcc
     3961 aatgaagcag ctgtacaatt taattacgga aatcaaacga ttgtaaccta cgttcgcgtt
     4021 ttatctgttg tagagaccat ggaaacaact ttaaaattaa aagatttgga tgaagaggga
     4081 ctatatgaat tacaggaaaa tggcgaagtt tactcaggtg cagaactaat gtatgcgggc
     4141 ctaactgtta tcttatccca aggagatttt ttgagtagac agtatatttt tagaagacta
     4201 tgataagggt gtataaattt ataaaggagg ctttctaatg gaatggtata aaaaaatcgg
     4261 acttcttgca actacaggtt tagctttgtt tgggctcggc gcttgctcca actatggtaa
     4321 atctgcggat gacacagtga ccatcgagta tttcaaccag aaaaaagaaa tgaccaaaac
     4381 cttggaagaa atcactcgtg attttgagaa ggaaaaccct aagatcaagg tcaaagtcgt
     4441 caatgtacca aatgctggtg aagtattgaa gacacgcgtt ctcgcaggag atgtgcctga
     4501 tgtggtcaat atttacccac agtccatcga actgcaagaa tgggcaaaag caggtgtctt
     4561 tgaagatttg agcaacaaag actacctgaa acgcgtgaaa aatggctacg ctgaaaaata
     4621 tgctgtaaac gaaaaagttt acaacgttcc ttttacagct aatgcttatg gaatttacta
     4681 caacaaagat aaattcgaag aactgggctt gaaggttcct gaaacctggg atgaatttga
     4741 acagttagtc aaagatatcg ttgctaaagg acaaacacca tttggaattg caggtgcaga
     4801 tgcttggaca ctcaatggtt acaatcaatt agcctttgcg acagcaacag gtggaggaaa
     4861 agaagcaaat caataccttc gttattctca accaaatgcc attaaattgt cggatacgat
     4921 tatgaaagat gatatcaagg tcatggacat ccttcgcatc aatggctcta agcaaaagaa
     4981 ctgggaaggt gctggctata ccgatgttat cggagccttc gcacgtgggg atgtcctcat
     5041 gacaccaaat gggtcttggg cgatcacagc gattaatgaa caaaaaccga actttaagat
     5101 tgggaccttc atgattccag gaaaagaaaa aggacaaagc ttaaccgttg gtgcgggaga
     5161 cttggcatgg tctatctcag ccaccaccaa acatccaaaa gaagccaatg cctttgtgga
     5221 atatatgccc cgtccagaag tcatgcaaaa atactacgat gtggacggat ctccaacagc
     5281 gatcgaaggg gtcaaacaag caggagaaga ttcaccgctt gctggtatga ccgaatatgc
     5341 ctttacggat cgtcacttgg tctggttgca acaatactgg accagtgaag cagacttcca
     5401 taccttgacc atgaactatg tcttgaccgg tgataaacaa ggcatggtca atgatttgaa
     5461 tgccttcttt aacccgatga aagcggatgt ggattaggag tagagagact atgaaaaaag
     5521 tattacaaaa atattgggca tgggcttttg tggtcatccc cctcttgtta caagcaattt
     5581 tcttctatgt gccgatgttt caaggagcct tttacagttt taccaactgg acaggattga
     5641 cttacaacta caaatttgtc ggcttaaaca actttaagct cctcttcatg gatccaaaat
     5701 tcatgaatgc gattggcttt accgcaatca ttacgattgc catggtggtt ggtgagattg
     5761 cactcgggat cttcattgcg cgtgtcttga actctaaaat caaaggccaa accttcttcc
     5821 gtgcttggtt cttcttccca gctgttttat ctggtttgac agtggctttg atcttcaagc
     5881 aagtcttcaa ctacggtctt ccagcgattg ggaatgccct tcatattgaa tttctccaaa
     5941 ccagtctttt agggactaag tggggagcaa tctttgcggc tgtctttgtc cttctttggc
     6001 aaggggtggc tatgcccatc atcatcttcc tagctggttt gcaatctatt ccaactgaga
     6061 ttacagaggc agcaaggatt gatggtgcga ctagcaagca agttttctgg aacattgaat
     6121 tgccttactt gctaccaagt gtctctatag tctttatcct agccctaaaa ggtgggctga
     6181 ctgcctttga ccaagtcttt gccatgaccg gtggtggtcc aaacaatgcc acaacctcac
     6241 ttgggctctt ggtttataac tatgccttta aaaacaacca attcggttat gccaatgcca
     6301 ttgccgtaat cttgttcttc ttaattgtag tgatttcgat catccaattg agagtatcta
     6361 agaaatttga aatttaagag gagaagcatg atgaaacaag atgaaagaaa agccctgatt
     6421 ggcaaataca ctctattgat tctaggaacg gttctgattt tagtgccgct ccttgctacc
     6481 ctctttagtt ccttcaaacc cactaaggat attgtagata atttctttgg atttccaacc
     6541 aacttcacat gggacaactt tagccgtctc ttagctgatg ggattggagg ctattattgg
     6601 aactctgtcg tcatcactgt cttgtcttta cttgcagtaa tgatctttat ccctatggca
     6661 gcctactcca tcgctcgcaa tatgagtaaa agaaaagcct ttaccatcat gtataccctc
     6721 ttaatcctcg gaatcttcgt acctttccaa gtcatcatga ttccgattac ggttatgatg
     6781 agtaaactcg gtttggctaa tacctttggt ttgatcttgc tctacttgac ctatgcgatt
     6841 ccacagaccc tctttctcta tgttggctat atcaaaatct cgattccaga aagtctggat
     6901 gaagcagcag agatcgatgg ggctaatcaa tttacaacct atttccgcat catcttccca
     6961 atgatgaaac cgatgcatgc gacaaccatg atcatcaatg ccctttggtt ctggaatgac
     7021 ttcatgttgc cactccttgt cttgaaccgg gattccaaaa tgtggactct gcctttgttc
     7081 caatacaact acgcaggcca atatttcaac gactacggac caagctttgc ctcttacgtg
     7141 gtcggcatta tcagtatcac cattgtctat ctcttcttcc aacgccatat catttcagga
     7201 atgagcaacg gggcagtgaa gtaatactca atgaaaatca aagagcaaac taggaagcta
     7261 gccgcaggct gtacttgagt acggcaaggt gaagctgacg tggtttgaag agattttcga
     7321 agagtataag aagagctcat ggaatctata gtctttgaca cagaggaaga gttcagcttg
     7381 ttgataattc tatgtagaaa acaagaaagt agtactttgt ttatcacagt ctatattagt
     7441 acgagtttga tgataaatag agatttaaaa tgaatttgat ttacgaagcc agatcatatg
     7501 agacttggct tcaattagaa aaaggagagt aatgatgccg attcaaaata aaaccatgtt
     7561 gattacctat tctgatagcc ttggaaataa tcttaaagac ttatatgata atttggaaga
     7621 gcattttgga gatgctattg gaggagttca ccttttacca tttttcccat caacaggtga
     7681 tcgtggattt gcgccagttg actacgacga agtggactca gcttttggtg attgggagga
     7741 tgttaagcgt ttaggtgaga aatattatct tatgtttgat tttatgatta atcatatttc
     7801 tcgtcaatcc aagtattata aggactatca agaaaaacat gaagccagtg aatttaaaga
     7861 tctcttttta aactgggata agttttggcc agaaaaccgt ccgacacagt ctgatgtaga
     7921 tttaatttac aagcgtaagg atcgtgcacc aaagcaagag attgtgtttg aagatggttc
     7981 agtggaacat ttgtggaata cctttggtga ggagcagatt gatcttgatg tgaccaaaga
     8041 agtaactatg gaatttatcc gtaagaccat tcagcacttg gcaagtaatg ggtgtgattt
     8101 gattcgtcta gatgcctttg cttatgcagt gaagaaattg gatactaatg atttctttgt
     8161 ggaaccagat atttgggatt tattggacaa agttcgagat atcgctgctg agtatgggac
     8221 agagctttta cctgagattc atgaacacta ttcgattcag tttaaaatag cagaccatga
     8281 ttactatgtt tatgattttg ctcttccaat ggtgacactt tatactcttt acagttccag
     8341 aacagagcgt ttggctaagt ggttaaagat gagcccgatg aagcaattta cgacgctaga
     8401 tacccatgat gggattggag tagtagatgt caaggatatc ctgaccgatg aggagattga
     8461 ctatgcttca aatgaactct ataaggttgg agctaatgtc aaacgtaagt actctagtgc
     8521 cgagtataac aacttagata tctaccaaat caattcaacc tactattcag cgcttggaga
     8581 tgatgatgtc aagtattttc tcgctcgtct aattcaagct tttgccccag gtattcctca
     8641 ggtttactat gtgggtctat tagcaggcaa gaatgacttg aaattattag aagaaactaa
     8701 agaaggtcga aatattaatc gtcattacta tagcaacgag gaaatagcaa aagaagtgca
     8761 acgacctgtt gtgaaggctc ttctcaatct attttctttc cgtaaccgtt cagaagcctt
     8821 tgatctagaa gggactactg agatagagac accaacagct cacagcattg taatcaaacg
     8881 tcaaaataaa gataagtccg taacagcagt agcagaaatt gatttgcaaa atcagactta
     8941 tcgggtaatt gagaatggag ttgaagtaac attttgaagc cttgatatgg tggataaaat
     9001 agggttttta ttttggaaaa cgtttccttt gttttcaaat tgctaaaaaa gtggtacaat
     9061 ataggatagc ttactattat ctgaatcagc tgatttggag agaaaggatt cattttgaaa
     9121 tcaataggct ttattgaaaa gctgaagggg ttgtctagta aagagctgat tttattggga
     9181 attatcctga gtatcttttt acccttttat ctttttgtag ttgtactctg tttatatatt
     9241 atcagtttga tttttacagg agacatgaaa agtattcttc agaaaatggg ggagcatccg
     9301 atgctgcttc tttttcttag ctatagtact gttatatcca ttcttgcaca aaattggatg
     9361 ggtcttgtgg cttcagtagg aatgtttcta tttactattt tctttttgca ctatcagtcg
     9421 attttatccc ataaattctt tcgattgatt ttgcagtttg tcttgtttgg tagtgtcttg
     9481 tcagctgctt ttgccagttt agaacatttc caaattgtga agaaatttaa ctatgctttt
     9541 ctttcaccca atatgcaggt gtggcatcag aaccgggcag aagtgacctt ctttaatcct
     9601 aattattatg gaattatttg ttgtttctgt attatgattg ctttctatct gtttacaacg
     9661 accaagttga attggttgaa agtattctgt gtgattgcag gctttgttaa tctctttggt
     9721 ttgaacttta ctcaaaatcg aactgccttt cctgctatta tcgctggagc aattatctat
     9781 ctctttacga ctattaaaaa ctggaaggcc ttttggctta gtattggggt cttcgcgatt
     9841 ggtttgagtt tcctcttttc tagtgatttg ggagttcgaa tgggtacttt agactcttct
     9901 atggaagaac gcatttctat ctgggatgct gggatggcct tgtttaagca aaatcctttt
     9961 tggggtgaag ggccattgac ctatatgaac tcttatcctc ggatacatgc tccttatcat
    10021 gaacatgccc acagtcttta tattgatacg attctgagtt acggaattgt ggggactatt
    10081 ttattagttt tgtcttctgt tgctcctgtt cgcttgatga tggatatgag tcaggagtcg
    10141 gggaaacgtc cgattatcgg cctttatcta tctttcctta cagtggttgc tgtgcacgga
    10201 atttttgact tggctctctt ctggattcag tcaggcttta ttttcttgct agttatgtgc
    10261 agtattccat tggagcatcg aatgttggta tcggacatga cggattaagt tttataagtt
    10321 tgaaatcttc taccttgggt aggagatttt ttatacgatg ggcatgtcgt gcatctgagg
    10381 tgtaagtcct ctgtagggct ccactaccgg tgaatacaat agcgctcccc aagcctgact
    10441 atcgtgaggt agcggattaa aatggtctgg ggatagatcg ttttaagtct gacgcaggaa
    10501 ataagaattg tcagagaaag caatagtgaa atcgtaggct atgaatagaa acgtgatagc
    10561 gaggagcata tagtggataa ggtagcgaga aattttaaag tataaaagat agtcttaatc
    10621 tatatatgta aatcacaaaa gtaattgaat tcgggataag gttggtgtga aaagacatag
    10681 taaactgaat cttgaatact agaatgatac ttctacaata ttgttataat ttaatttgaa
    10741 ttccaaaatc acattgttcc gtccgtattt cattttactg tatgtcttcc taaactccaa
    10801 agtttctgcg tcaaatttcc tattttcact gtagtctttg acacttcgaa cgacaatttg
    10861 aatcatatat tcaaaaaaaa tgaaaaattt gtgccaacaa gcctaaatat tctgaaaatt
    10921 tgtttgattt ttaatggata atgtgatata atggttgtca atctataatt cacataaaca
    10981 gaggagtaga aaatgaaaaa aaatcgtgta tttgctacag caggtcttgt tttattagca
    11041 gcaggtgtac ttgcagcatg cagttcttca aaatcatctg attcatcagc ccctaaagct
    11101 tatggctatg tttatacagc agacccagaa accttggact acctgatttc aagtaaaaat
    11161 agtacaacag tagtgacttc aaatgggatt gatggtttat tcactaacga taattacggt
    11221 aatcttgctc ctgcagttgc agaggattgg gaagtctcta aggatggttt gacctacact
    11281 tataagattc gtaaaggggt taaatggttt acctctgatg gagaagaata tgcagaggtg
    11341 acggctaaag atttcgtgaa cggtttaaaa cacgcagcag ataaaaaatc agaagctatg
    11401 tatttagctg aaaattcggt taaaggcttg gcagattatc tatcaggaac ttcaacagat
    11461 ttttcaacag ttggtgtcaa ggcggttgat gattatacgt tacaatacac tttgaaccag
    11521 cctgaaccgt tctggaactc taagttgacc tattctattt tctggcctct gaatgaagaa
    11581 ttcgaaacat caaaaggaag cgattttgct aaaccaacag atccgacatc cttgctttat
    11641 aatggtccat tcttgttgaa agggttgact gcaaaatctt ctgtagagtt tgtaaaaaat
    11701 gagcaatatt gggataaaga aaatgtccac ctagatacta tcaatctagc ttactatgat
    11761 ggatcagatc aggagtcgct agagcgtaac ttcactagtg gagcttatag ttatgcccgt
    11821 ctttacccta ccagctccaa ctattctaag gttgcagaag aatacaagga caatatctat
    11881 tacacacaat caggctctgg gattgctggt ctgggtgtga atattgatcg ccaaagttac
    11941 aactatactt ctaaaactac agattcagag aaagtagcta ctaagaaggc attgcttaac
    12001 aaagatttcc gtcaagcctt gaattttgct cttgatcgct cagcttactc agctcaaatc
    12061 aatggtaaag atggagcagc tttagcagtt cgtaatttat ttgtaaaacc agactttgtt
    12121 tcagctggtg agaagacctt tggtgattta gtcgctgctc aacttcctgc ttatggtgat
    12181 gagtggaaag gtgtgaattt agctgatggg caggatggtt tattcaatgc tgacaaggcc
    12241 aaggcagagt ttgcgaaagc taagaaagct ttagaagcag acggcgttca gtttcctatt
    12301 catctggacg ttccagtaga ccaagcatca aaaaactaca tatctcgtat tcagtccttt
    12361 aaacaatctg tagaaacagt tcttggtgtt gaaaatgtcg ttgttgatat tcaacaaatg
    12421 acaagtgatg aattccttaa tattacttac tatgctgcca atgcttcatc tgaggattgg
    12481 gatgtatcag gaggagtttc atggggtcca gactatcaag acccatctac ttacctggat
    12541 attttaaaaa caactagcag tgaaactaca aaaacatatt taggatttga taatccaaat
    12601 agcccttcag tagttcaagt tggtttgaaa gaatacgata aattagttga tgaagctgcc
    12661 agagagacaa gcgacttgaa tgtccgttat gaaaaatatg cagcggctca agcatggttg
    12721 acagatagtt cactctttat tcctgctatg gcttcttctg gtgcagcacc agtgctttca
    12781 cgaattgttc catttactgg agcttctgcg caaacaggct ctaaggggtc agatgtttac
    12841 ttcaaatatt tgaaattaca agataaagtg gtgactaagg aagagtatga aaaagctcgt
    12901 gaaaaatggt tgaaagaaaa agctgaatca aatgagaaag ctcaaaaaga attggcaagt
    12961 catgtgaagt aaataatttc taatagaact ttctctccat gaggagaagg ttcttttggg
    13021 atttttaaag gaaataatat gaaaaaatat atttttatgc gtgttttgcg gtcattggtt
    13081 tcgattttct tagtaacgac tttgacctac acgattatct ataccttggt tcctcgaaaa
    13141 ttgattttca agcaggatcc taactataat aaaattgcga caacggctga taaacgtgat
    13201 aactatgaaa atactgtgtt tgagcgtatg ggctacattg agtattacga tactaaagag
    13261 ttgcaagaaa aggcaagtag catggattct tctgtaacag tagaagcaaa tgcgaccaat
    13321 aaagctattt atgaaaagta catcaatcaa ttaggtcatg gttggacttt gggagaattt
    13381 actgaaagtg gtcaattcta tgctactcgt gaaattccaa tttttgaacg tgtttttcac
    13441 ttctatgcta acttgattga cattgaccat acaaataaaa tccaagaccc tgaaaatcca
    13501 gacttgaaac gctaccttcg ttttgaaaat gatccagcta tcggatggtc attggtcggt
    13561 tcaggaacta aacataaata tctcttgtac tttaacagtc agttcccatt tgttcatcaa
    13621 aactttgtga acttgaattt aggtgactct tacccaacct atgctaatac accagttctt
    13681 caggttatta ctcaaggtca aggacaaacc aaaactgccc aagttcagtt cccaacaggt
    13741 aagaaaacgt cttctgtaaa tatttactca agaacctaca agtcacctag tcaggctgac
    13801 tctcgtgaag tagctagcta tgggaaagat gatccttata cagcgactga aagtaattac
    13861 caatatccat ctatgattgt cagctctgct attactggtt tgattggttt ggtgcttgcc
    13921 tatgctcttg ccgtgccact tggttcagcc atggctcgtt tcaagaacac ttggattgat
    13981 agcctctcaa caggggcttt gaccttcttg cttgctcttc caacgattgc cttggtttac
    14041 atcgttcgat tgattggatc atctatttcc cttccagatt cattccctat cttgggagct
    14101 ggagattggc gttcttacgt tttaccagca gtcatccttg gtttgttggg tgctcctggt
    14161 acagccattt ggattcgtcg ttacatgatt gacttgcaat ctcaagactt tgttcgtttc
    14221 gctcgtgcaa aaggtttgtc tgaaaaagaa atttcaaaca aacacatctt taaaaatgcc
    14281 atggttccgc tggtttcagg aattcctggt gccattattg gggttatcgg tggtgcaacc
    14341 cttactgaaa cagtcttcgc cttcccaggt atgggtaaaa tgttgattga ctctgtaaaa
    14401 gcatctaata actctatggt cgttggtctt gtcttcatct ttacatgtat ttctatcttc
    14461 tcacgtcttt tgggagatat ttggatgact attattgacc cacgtattaa attgactgag
    14521 aaaggaggca aataatgtct acaatcgata aagaaaaatt tcagtttgta aaacgtgacg
    14581 attttgcctc tgaaactatt gatgcgccag catattctta ctggaaatca gtgtttaaac
    14641 aatttatgaa gaaaaaatca actgtagtca tgttgggaat cttggtagcc atcattttga
    14701 taagtttcat ctacccaatg ttttctaagt ttgatttcaa tgatgtcagc aaggtaaacg
    14761 actttagtgt tcgttatatc aagccaaatg cggagcattg gttcggtact gacagtaacg
    14821 gtaaatcgct ctttgacggt gtctggttcg gagctcgtaa ctccatcctc atttctgtga
    14881 ttgcgacagt gattaacttg gttatcggtg tttttgtcgg tggtatttgg ggtatttcaa
    14941 aatcagttga ccgtgtcatg atggaagttt acaacgtcat ctcaaacatc ccacctcttt
    15001 tgattgttat tgtcttgact tactcaatcg gagctggatt ctggaatctg atttttgcca
    15061 tgagcgtaac aacatggatt ggtattgcct tcatgatccg tgtgcaaatc ttgcgctatc
    15121 gtgacttgga atacaacttg gcgtcacgta ctttgggaac accaaccttg aagattgttg
    15181 ccaaaaatat catgcctcaa ttggtatctg ttattgtgac aaccatgact caaatgcttc
    15241 caagctttat ctcatacgaa gccttcttgt ctttcttcgg tcttggatta ccgattacag
    15301 tgccaagttt gggtcgtttg atttcggatt attcacaaaa cgtaacaacc aatgcttact
    15361 tgttctggat tccattgaca acccttgtct tggtatcctt gtcccttttc gtagttggtc
    15421 aaaacttagc ggatgctagt gatccacgta cacatagata ggagtagaaa tgacaaaaga
    15481 aaaaaatgta attttgactg ctcgcgatat tgtcgtggaa tttgacgttc gtgacaaagt
    15541 attgacagcc attcgcggcg tttcccttga actagtcgaa ggagaagtat tagccttggt
    15601 aggtgagtca ggatcaggta aatctgtttt gacaaagacc ttcacaggta tgctcgaaga
    15661 aaatggtcgc attgcccaag gtagtattga ctaccgtggt caggacttga cagctttatc
    15721 ttctcacaag gattgggaac aaattcgtgg tgctaagatt gcgactatct tccaggaccc
    15781 aatgactagt ttggacccca ttaaaacaat tggtagtcag attacagaag ttattgtaaa
    15841 acaccaagga aaaacagcta aagaagcgaa agaattggcc attgactaca tgaataaggt
    15901 tggcattcca gacgcagata gacgttttaa tgaataccca ttccaatatt ctggaggaat
    15961 gcgtcaacgt atcgttattg cgattgccct tgcctgccga cctgatgtct tgatctgtga
    16021 tgagccaaca actgccttgg atgtaactat tcaagctcag attattgatt tgctaaaatc
    16081 tttacaaaac gagtatcatt tcacaacaat ctttattacc cacgaccttg gtgtggtggc
    16141 aagtattgcg gataaggtag cggttatgta tgcaggagaa atcgttgagt atggaacggt
    16201 tgaggaagtc ttctatgacc ctcgccatcc atatacatgg agtctcttgt ctagcttgcc
    16261 tcagcttgct gatgataaag gggatcttta ctcaatccca ggaacacctc cgtcacttta
    16321 tactgacctg aaaggggatg cttttgcctt gcgttctgac tacgcaatgc agattgactt
    16381 cgaacaaaaa gctcctcaat tctcagtatc agagacacat tgggctaaaa cttggcttct
    16441 tcatgaggat gctccaaaag tagaaaaacc agctgtgatt gcaaatctcc atgataagat
    16501 ccgtgaaaaa atgggatttg cccatctggc tgactaggag gaaggaaatg tctgaaaaat
    16561 tagtagaaat caaagattta gaaatttcct tcggtgaagg aagtaagaag tttgtcgcgg
    16621 ttaaaaatgc taacttcttt atcaacaagg gagaaacttt ctcgcttgta ggtgagtccg
    16681 gtagtgggaa aacaactatt ggtcgtgcta tcatcggtct aaatgataca agtaatggag
    16741 atatcatttt tgatggtcaa aagattaatg gtaagaaatc gcgtgaacaa gctgcggaat
    16801 tgattcgtcg aatccagatg attttccaag accctgccgc aagtttgaat gaacgtgcga
    16861 ctgttgatta tattatttct gaaggtcttt acaatcaccg tttatttaag gatgaagaag
    16921 aacgtaaaga gaaagttcaa aatattatcc gtgaagtagg tcttcttgct gagcacttga
    16981 ctcgttaccc tcatgaattc tcaggcggtc aacgtcaacg tatcggtatt gcccgtgcct
    17041 tggtcatgca accagacttt gttattgcag atgagccaat ttcagccttg gacgtttctg
    17101 tacgtgccca agtcttgaac ttgctcaaaa aattccaaaa agagctcggc ttgacctatc
    17161 tcttcatcgc ccatgacttg tcggttgttc gctttatttc agatcgtatc gcagttattt
    17221 acaagggtgt tattgtagag gttgcagaaa cagaagaatt gtttaacaat ccaattcacc
    17281 catatactca agccttgctt tcagcggtac caatcccaga tccaatcttg gaacgtaaga
    17341 aggtcttgaa ggtttacgac ccaagtcaac acgattatga gactgataag ccatctatgg
    17401 tagaaatccg tccaggtcac tatgtttggg cgaaccaagc cgaattggca cgttatcaaa
    17461 aaggactaaa ctagtaatgg ttttataatt tccatgtcaa tctttatgga aattataaaa
    17521 ctttttttgt tggactgatt tgaaaaactt tgaaagcttc ctgaaagaac tttcgaaaaa
    17581 ttttaaaaaa ttctgaaata ttattgacag gtgatgaaaa aggtggtagg ataggaagga
    17641 tcaaaaaaga aagcagaaaa agaaatgaat aagagacaag ccgtaactat gaatcaaaac
    17701 ttttacttta gctactttag atagtgtttg tagacatgtc accagggatg caaacagttc
    17761 aagcaatttg tttgtatcta tgtggttaag atttttgatt gtggtccata tagatgaata
    17821 tctaaatgga ctagctaagt tgtaacttgt taggttattt caagtatccg tttagatagt
    17881 atctaggcgg ttttttgttt tatcttttct gagaaggagt ttcattatga aagttgttcg
    17941 aaaatcacta gccccctctt ggtagtgggg ctcctcttga cttctctgat cagtttgcat
    18001 cagttgaagg cagataagaa aaagatgtct tttgtatcgg tatttcgcag tttattaccc
    18061 accagtcctt agacgctact agagaaggat ttgtggatga gctggccaaa caaggctatg
    18121 ttgaagggga aaatattgag attgatttgc aaaatgcaca gggagaacaa agaaatctaa
    18181 aaacgatttc ccagcaacta gcagaatcca gcgatgtcgt tctagccatc gcaaggcctt
    18241 ctgctcagag cttggccaat acgacgcaaa cgacaccagt tatcttttca gctgtaacag
    18301 ccccagtcag tgccaagttg gttgagtcaa gagaacatcc tgggggcaat gtaactggga
    18361 caagcgatca gtcatcagat gccatttcaa cccaagtcaa tttgataaag aaagtgttgc
    18421 caaaggctaa aacgattgga atcctctata ctcagagcga gcccaattcg gttgttcaaa
    18481 aggatgaaga taagcgactt ctgaaagaaa aaggctttac cgttgttgaa aaaacaatct
    18541 tggacagtaa taacgtcaag gcggcagcag agaatttgat ggcagaggtg gatatggttt
    18601 ttgtcccaac tgataatatc atttcgtcaa ccatggaaac agttaagcag gtttctatta
    18661 aacacaaggt tccagtattc ggtggttcaa cagaaatgat tgctgttggt gacttgtata
    18721 actacggaac caattatgaa gaattgggaa gacagacagc tcgcatgctg attcgtgttt
    18781 taaaaggtga gaaaccagaa aatatagcag ttgagttgcc tgaaaaactg gaattgcata
    18841 ctaatcaaga aatggcagat gcattgggaa ttgatattag taagttagaa ggcaaggaat
    18901 aaggaggatt aagatgaatt ttgtgttatc tagtttatca gaaggtttgt tgtggtcgat
    18961 tgtggcgatt ggggtctact tgactttccg tattttggat attgcggata tgactgctga
    19021 gggagccttt cctctggggg cagcagtcgt tgtatcacag atacaggcag gggcaaatcc
    19081 ttggcttgcg attttacttg ctttgctggc aggtatggta gcaggtcttg tatcaggaat
    19141 gctccacacc aagatgaaaa tcccagctct cttgacaggg attgtgacct tgacagggct
    19201 ctattcaatc aatattaaaa tcatgggcag tgtactcaat ctttccttgg gagattctgc
    19261 aaccgtcttt aaacagttgg cgagcttggg tctgacaaat gaaggagctg ttttctcact
    19321 tagtttagtc tgtctcttac ttgtttggtc ttgacccttt tgatgaaaac agagattggt
    19381 ttggtcttgc gttcgactgg ggataatatc ccgataagtg aggccaatgg agtcaatgta
    19441 gacaccatga agattgttgg ttacatgatt tcaaacggtt tgattgctct atgtggttcc
    19501 ttgtttgccc aaaatgatgg attttcagat gtgacttctg ggacaggaac cattgttgtt
    19561 ggtttgagct cggtgattat tgcggaagtc ttgatacacg acttgaccat tggaggccgc
    19621 ttattatcca tcggaatcgg tgctattgtt taccgtttga ttattttaaa tatctatgaa
    19681 attccaaatc tagatcaaaa cttggtacgt ctctttaatg caatcttgct cactttggtt
    19741 ttatttgcac cagaattgca aaagagatta aagattcgtg gtctgaaatt gagaaatgaa
    19801 taggaggaga aagttatggc aagtttgtta acacttgaaa atattcacaa gacatttgaa
    19861 gcagggacgg tcaatgagaa ccatgtcctc aaaggattag atttagaggt tgaagaggga
    19921 gattttatct ctgtgattgg tggaaatgga gcaggaaaat ccactttgat gaatatcttg
    19981 gctggcaatc tatcggtgga cgaaggggac cttctactgg cagggaaatc cattaaaaat
    20041 ctgagtgtta gaaagagagc caaggatatt gcccgtgttt ttcaagatcc taagatggga
    20101 acagcttcta gtttgacgat tgaggagaat atggctattg ccttgagacg tgggcaaaag
    20161 agagggcttg gttggggcgt gaaggagaag gatagaatcc agttccaaga ggccttgaag
    20221 gagttgaata ttggtcttga aaaccgctta aaagtagata ctcaatatct ctcaggagga
    20281 caaagacagg ctttgaccct agtcatggca gctctggtga aacccaaact tttgcttttg
    20341 gatgaacata ctgcggcact tgacccgaaa accagtcaaa tggtgatgga cttgacgcaa
    20401 aagattgtgg agcaccatca gtggacgact ttgatgatta cccatgatat gaatcatgcg
    20461 attgagtacg gcaatcgtct cattatgctc tatcaaggaa agatagtggt agatgtcaag
    20521 ggagaagaga aaaagcatct gacagttgaa gaccttatgc atctcttcca gaaaaatagt
    20581 ggccaaagtc tggtcagtga tgaattagtt ttgggataaa gaaaaaggct gagatctggt
    20641 gtctcagtct tttatttctt gcgttttgca aaatctacaa atctaaattt ctctaactta
    20701 tggcgacttt cggtaaactg aaattggcgt ccgtcttgga gatagacttt tgatttaatc
    20761 gaaacgacat aagggtcttt gccaatgtcc atgagaatct tgtctcggtc gcttgagtgg
    20821 tcaatggtga tttccttctg agcataatca ataaggagtt tgaggccatt ttctatataa
    20881 gaatagatag actgctcagc aatttggcga gtgagatttg gaattagttc catatccaga
    20941 tagtccgtat ccagaacgga taccagatca tccaccacac gctggcggac caccttccaa
    21001 accatccgaa actctgggaa accggttatc agtgaggatt ttttatcaat aataatcttg
    21061 tccagactga ccacgttggt tttagagcgc agtccaagtt ctttaactag ttcttggtag
    21121 ctggttaggt tggatacagg gaaattgacg gtttcttctt tgacgacttg agaaccttgc
    21181 cctcttatct ttttgatcaa tccttcctct tggaggagag acagggcctt tcggacggta
    21241 tcacgactca cttgatattg ctccataagg tcgtgctcgc taggaaggaa atctccgaca
    21301 gcgtaagtct cgttttgaat ggtttcttgg atttgcttaa ataattgttg gtatttcttc
    21361 attttgcctg cttaaatagg tttttagtct agtttaatga acacctgtat atattttacc
    21421 atacaagtgc tagaaaattt acaaaaaaac acccttttta taccaaacaa gttgtagaca
    21481 agtttggtat cgtttacaat atacttatca aatcaaactt gctttgacaa gtataaggag
    21541 aatcaaatgg gaaaatttga acaagaagcc aaagatctgc ttcaggcaat tggaggcaaa
    21601 gaaaatgtga ctgccgtaac tcactgtgcg acacggatgc gctttgtttt aagagatgat
    21661 aagaaggcta atgttaaagc tatcgagtca attccagctg ttaaaggaac ttttacaaat
    21721 gcaggtcaat ttcaggtaat cattggaaat gacgtgccca tcttttataa tgattttaca
    21781 gccgtttcag gtattgaggg tgtttccaaa gaagcagcca agtctgcagc taagagtaat
    21841 caaaacgtgg tccaaggtgt tatgaccact ctggcggaaa tctttactcc gattattcca
    21901 gccttgattg ttggtggatt gatcctcggt ttccgtaatg tcttggaagg tgtccattgg
    21961 tcgatgttgg atggcaagac catcacagaa tcctctcagt tttgggcagg ggttaatcac
    22021 ttcctctggt tgcctggtga agctatcttc cagttcttac cagtagggat tacttggtct
    22081 gtttctcgta agatgggaac cagccaaatt ttgggaattg ttctcggaat ctgtttggta
    22141 tcgcctcagt tgctcaatgc ctatgcggtt gcttcaacgc cagcagctga tatcgcagca
    22201 aactgggttt ggaattttgg ttattttact gttaatcgta ttggttacca agcccaagtt
    22261 atcccagcct tgcttgcagg tttgagtctg tcttatcttg aaattttctg gcgcaaacat
    22321 atcccagaag tcatttccat gatttttgta ccttttttgt cattgattcc agccttgatt
    22381 ttggctcata ctgttttggg accaatcggt tggacaattg gacaaggact ttcatcagtt
    22441 gtcttggcag gtttaactgg tccagttaaa tggctcttcg gtgcaatttt tggtgccctc
    22501 tacgctccat ttgtcatcac aggtctgcac cacatgacca atgccattga tacacaattg
    22561 attgcggatg ctggtggcac tgccctctgg cctatgattg ctctttctaa tattgctcaa
    22621 ggctcagccg tgtttgccta ttatttcatg catcgccatg atgagcgtga ggctcaggtt
    22681 tcacttcctg caaccatttc agcctatctc ggtgttacag aaccagctct ttttggggtt
    22741 aacgtaaaat atatttatcc atttgttgct gggatgactg gttcagccct tgcaggcatg
    22801 ttatccgtta cttttaatgt aactgcggct tctattggta tcggtggttt gccaggtatt
    22861 ctctctattc aacctcaata catgctgcca tttgcaggaa ctatgctagt tgcgattgtt
    22921 gttccaatgc tcttgacttt cttcttccgc aaggctggtc tctttacaaa aacagagggc
    22981 gatacgaact tgcaggcaga attcgttgct caagaagaag cagaatttgt gaaccatgaa
    23041 ccagtagaac ttacttcggt agaaattatc agcccactaa ctggccaagt gaaagaattg
    23101 agtcaagcga cggatcctat ttttgcatca ggtgtcatgg ggcaaggtct ggtcattgaa
    23161 ccaagccaag gtgagttgac ctctccagtt aatgggacag tgacggttct tttccctacc
    23221 aagcatgcca tcggcattgt ctctgacgag ggagttgaat tgctcatcca catcggtatg
    23281 gatacagtag gtcttgatgg caaaggtttt gaaagtcttg tagtccaagg agatcacgtt
    23341 acagttggtc agcaactgat tcgttttgat atggatgtca ttaaggctgc aggtctggtg
    23401 acagaaactc ctgttatcat caccaaccaa gatgcttata cagcgactat tcccggaact
    23461 tatccgacaa cgatccaagc tggagcatct ctcatggtcg ctacacgaat ctaatactct
    23521 tcgaaaatct cttcaaacca cgtcagctct atctgcaacc tcaaaatagt gttttgagca
    23581 acctgtggct agcttcctag tttgttcttt gattttcatt gagtataatt gaaatagcac
    23641 aaatagggac ggaagactgc ttcctccctt ttatcagaaa aggagaaaca gatgacactt
    23701 gataaaggaa aagtagtcta tcaaatctat ccaaaatctt acaaagacac cactgaaaac
    23761 ggtattgggg atttccgtgg gattatcgaa aaaattccct atttagccaa actaggtgtg
    23821 gatatggtct ggctcaatcc attctatcca agccctcaac gggataatgg ttacgatatt
    23881 tcagattata tggcagtgga tcctcttttt ggtgatatgg ctgattttga ggaaatggtg
    23941 tgtgtcggta aagagcacaa gattgacttt atgctggaca tggtacttaa tcattgttcg
    24001 acagagcatg aatggtttca gaaagcccta gctggtgata agtattatca agactttttc
    24061 ttcatccaag accaaccaac agattggcag tctaagtttg gtggttctgc atgggcgcct
    24121 ttcggggata ctgggaaata ctatcttcac ctatttgatg agacccaggc tgaccttaac
    24181 tggcgcaatt ccaatgtccg taaggagctt ttcaaggttg ttaatttctg gcgcgacaag
    24241 ggtgtcaaag gttttcgatt tgatgtgatc aatttgatcg gtaaggacga ggtttcagtg
    24301 gactgtcctg aaaatgaagg gaagccagct tatacagaca aacccatcgt tcataactat
    24361 ttgcgtatga tgaaccaagc cacttttgga tctgacgata gctttatgac agttggggaa
    24421 atgtcttcta ccaccatgga aaactgtgtc ctctattcgt cgcctgatcg tcaggaatta
    24481 tccatgacct ttaattttca tcacctcaag gtggactata aggatggaca aaagtggacc
    24541 ttggctccct ttgattttga agagttgaag agtctttacc atagttgggg taaggaaatg
    24601 agtgataaag acggttggag tgccctcttt tggaacaatc acgatcaacc acgtgccttg
    24661 aaccgttttg tcgatattca aaacttccgc aaggaaggag ccaccatgct agcagccagc
    24721 attcacctgt cacgtgggac accttatatc tacatgggtg aggaaatcgg gatgattgac
    24781 ccagactatg attctatggc tgattatgtg gatgtcgaat cgcttaatgc ctatcagatg
    24841 ctcttagaag aaggaaagag tcagcaagaa gccttccaga ttattcaagc taagtcgcgt
    24901 gataattcac gcattcccat gcagtgggat gcttcggaaa atgcaggatt ttcaacaggc
    24961 actccttggt tgaaagctgg taaatcctat aaatacatca atgtagaaaa tgaaatccag
    25021 ggtccgattt ttaccttcta tcaagacttg attcgactgc gtaaggaaat gccaatcatt
    25081 tcagaaggaa gttacaaacc agcctttgaa gatagcaaac aagtctacgc ttttgaacgc
    25141 cagtttgagg atcaaaagtt actagtgctc aataactttt atgctaaaga agtggaaatc
    25201 gacttgccag cagtctacca aaatggacag attttgatat caaactatga agatgcagaa
    25261 gtgtctgaga aaattctact caaaccctat caaacactgg ctatttatgt aaattaatac
    25321 tcttcgaaaa tctcttcaaa ccgtgtcagt tttatctgca acctcaaagc ggtgctttga
    25381 gcaacctgtg gctagcttcc tagtttgctc tttgattttc attgagtata aacttagcaa
    25441 ggagacctct ttttcagaaa agcagggttc tttttgctgt ctattccatc cctgaaagtg
    25501 tagaacaaac tggtcagggt ggctagtttg tggtataatg aaagggactc aaaaagaaac
    25561 aggagaaaaa tgatggattt acttttagca attgtattga ttgtgctagc ttttctagga
    25621 ggagctcttg gaggaatgta cttggttcgt aagcaaatcg aaaaagaatt tgctgacaac
    25681 ccacgtttga atgctgaagc agttcgtact cttttgagtg caaatggtca aaaaccaagc
    25741 gaagctaagg tacaacaagt ttaccaccaa atcatccgcc aacaaaaggc agcccttgct
    25801 aacaataaaa agaaaaaata aataaggaaa agtctgggat gaaagttcca gacttctcac
    25861 tatgttggtt atggtttagg gatgagactt tttccttgca ttctattgat atttgattat
    25921 gattaagaga gaggtagttg acattctatc aagctgtcgg tcagttcgtt cagtacaagg
    25981 aatcataatg aacgatcaat cagaaaaaag actagaaaga agactgtatg gataatcgac
    26041 caattggttt tttggattcg ggtgtcgggg gcttgaccgt tgtgcgcgag ctcatgcgcc
    26101 agcttcccca tgaagaaatc gtctatattg gagattcggc gcgggcgccc tatggccccc
    26161 gtcctgctga gcaaattcgt gaatatactt ggcagctggt caactttctc ttgaccaagg
    26221 atgtcaaaat gattgtcatt gcttgtaaca ctgcgactgc ggtcgtctgg gaagaaatca
    26281 aggctcaact agatattcct gtcttgggtg taattttgcc aggagcttcg gcagccatca
    26341 agtccagtca aggtgggaaa atcggagtga ttggaacgcc catgacggta caatcagaca
    26401 tataccgtca gaaaatccat gatctggatc ccgacttaca ggtggagagc ttggcctgtc
    26461 ccaagtttgc tcccttggtt gagtcaggtg ccctgtcaac cagtgttacc aagaaggtgg
    26521 tctatgaaac cctgcgtccc ttggttggaa aggtggatag cctgattttg ggctgtactc
    26581 attatccact ccttcgccct attatccaaa atgtgatggg gccaaaggtt cagctcatcg
    26641 atagtggggc agagtgcgta cgggatatct cagtcttact caattatttt gaaatcaatc
    26701 gtggtcgcga tgctggacca ctccatcacc gtttttacac aacagccagt agccaaagtt
    26761 ttgcacaaat tggtgaagaa tggctggaaa aagagattca tgtggagcat gtagaattat
    26821 gacaaataaa atttatgaat ataaggatga ccaggactgg tatgttgggt cttatagtat
    26881 ttttggtggc gttaacagtt tgagcgacta taagacagat tttcctctgt ttgaattctc
    26941 caaaatattt ggagatgaag agtatggttt cccgctttca gttactgttt tacgctatgg
    27001 ttctacctac cgtttgttct cctttgtggt agacatgctt aatcaagaaa tgggacgaaa
    27061 cttggaagtt attcaacgtc atggggccct gctcttggtt gaaaatgggc aactcttgta
    27121 tgtagaattg cctaaagaag gggtcaatgt tcatgatttc tttgagacaa gcaaggtcag
    27181 agaaaccttg ttgattgcga ctcgtaacga aggtaaaacc aaggaattcc gagctatctt
    27241 tgataagtta ggctacgatg tggaaaatct taatgactac cctgacctgc ctgaagtagc
    27301 agaaacaggt atgacctttg aagaaaatgc ccgccttaag gcagaaacca tttctcaatt
    27361 aacgggcaag atggttttgg cagatgattc tggtctcaaa gtcgatgtcc ttggtggctt
    27421 accaggcgtc tggtcagctc gtttcgcagg tgtgggagca actgaccgtg aaaataatgc
    27481 caaactcttg cacgaattgg ccatggtctt tgaactcaag gaccgctcgg ctcagttcca
    27541 cacaacccta gtcgtagcca gcccaaataa ggaaagttta gttgttgaag cagactggtc
    27601 aggttatatt aactttgaac ctaagggtga aaatggcttt ggctatgatc ccctcttcct
    27661 tgtaggagag acaggtgagt catcagctga attaaccctg gaagaaaaaa atagtcaatc
    27721 tcaccgtgcc ttagccgtta agaaactttt ggaggtattt ccatcatggc aaagcaaacc
    27781 atcattgtaa tgagcgattc ccatggcgat agcttgattg tggaagaagt ccgtgatcgc
    27841 tatgtgggca aagtcgatgc cgtttttcat aacggcgatt ctgaactacg tccggattct
    27901 ccactttggg agggcatccg cgttgttaaa gggaacatgg acttctacgc cggctaccca
    27961 gaacgtctgg tgactgagct tggttcgacc aagattatcc aaactcatgg tcacttgttt
    28021 gacatcaatt tcaactttca aaagttggac tactgggctc aggaggaaga ggccgctatc
    28081 tgcctctatg gtcacttgca tgtgccaagt gcttggatgg aaggcaagat cctctttcta
    28141 aatccaggtt ctatcagcca accacgaggt accatcagag aatgtctcta tgctcgtgtg
    28201 gagattgatg atagttactt caaagtggac tttttgacac gagatcacga ggtgtatcca
    28261 ggtttgtcca aggagtttag ccgatgattg ccaaggagtt tgagactttc ttgttggggc
    28321 aggaggaaac ttttttgacc cctgctaaaa atctagctgt gttgattgat acccacaatg
    28381 cggatcatgc gaccctcttg ctcagtcaga tgacctatac ccgtgttccc gttgtgacag
    28441 atgaaaaaca gtttgttggg acgattggac tcagagatat tatggcttat cagatggagc
    28501 atgacttgag ccaagaaatc atggcggata cggatatcgt tcatatgaca aaaacggacg
    28561 tagcggttgt ttcgcctgat ttcaccatta cggaggtctt gcacaagcta gtagatgagt
    28621 ccttcttacc ggttgtggat gcagagggta ttttccaagg gattattacg cgcaagtcca
    28681 tcctcaaggc cgttaatgcc ctcttgcatg actttagtaa ggaatatgag attcgatgcc
    28741 aatgagagac aggatttcag cctttttaga ggaaaagcag ggcttgtctg tcaattccaa
    28801 gcagtcctat aagtatgatt tggagcaatt tttagacatg gtaggtgagc ggatttctga
    28861 gaccagtctc aagatttacc aagcccagct agccaatcta aaaatcagcg cccagaagcg
    28921 aaagatttcg gcctgtaacc aatttctata ctttctctat caaaaaggag aggtggacag
    28981 cttttaccgc ttggaattag ccaaacaagc tgaaaagaag acggaaaagc cagagattct
    29041 atacctagac tctttttggc aggaaagcga ccatccagag ggccgcttgc tagcgctctt
    29101 aatcctagaa atggggctct tgcccagtga gattttagcc atcaaggttg cggacatcaa
    29161 tctggatttt caggtgttgc gaatcagcaa ggcttcccaa cggaggattg tcaccattcc
    29221 cacggccttg ctttcagaat tggaaccctt gatggggcag acctatcttt ttgaaagagg
    29281 agggaaaccc tattctcgtc agtgggcctt tcgtcagtta gaatcttttg tcaaggagaa
    29341 aggttttcca tccttatcag ctcaagtctt acgtgaacag tttattctaa gacaaataga
    29401 aaacaaggtc gatttgtacg aaattgcaaa aaaattagga ttaaaaacag tcctgacctt
    29461 agaaaaatat agataatgga tattaaatta aaagattttg aaggacccct ggacttactc
    29521 ttgcatctgg tttctaagta ccagatggat atctacgatg tgcccattac ggaagtcatc
    29581 gaacagtatc tagcctatgt ctcaaccctg caggccatgc gtctggaagt gacgggtgag
    29641 tacatggtca tggctagtca gctcatgctg attaagagtc gtaaactcct tccgaaggta
    29701 gcagaagtga cagacttggg ggatgacctg gagcaggacc tcctctctca aatcgaagaa
    29761 tatcgcaagt tcaagctctt gggtgagcac ttggaagcca agcaccaaga acgggcccag
    29821 tattattcca aagcgccgac agagttgatt tacgaagatg cggagcttgt gcatgacaag
    29881 acgaccattg acctcttttt ggctttttca aatatcctag ccaagaaaaa agaggagttt
    29941 gcacaaaatc acacgactat cttgcgggat gagtataaga ttgaggacat gatgattatc
    30001 gtgaaagaat ccttgattgg acgagatcaa ttgcgcttgc aggatttgtt caaggaagcc
    30061 cagaatgtcc aagaggtcat caccctcttt ttggcaaccc tagagttaat caaaacccag
    30121 gagctgatcc tcgtgcaaga ggagagtttc ggagatatct atctcatgga aaagaaggaa
    30181 gaaagtcaag tgcctcaaag ctcgacttga tagagaggaa agatgagtac tttagcaaaa
    30241 atagaagcgc tcttgtttgt agcgggtgaa gatgggattc gggtccgcca gttagctgaa
    30301 ctcctctctc tgccaccgac aggcatccag caaagtttag gaaaattagc ccagaagtat
    30361 gaaaaggacc cagattccag tttggctttg attgagacaa gtggtgctta tagattggtg
    30421 accaagcctc aatttgcaga gattttgaag gaatactcta aggcgcctat caaccagagc
    30481 ttgtctcggg ctgcccttga gaccttgtcc attattgcct acaaacagcc gattacgcgg
    30541 atagaaattg atgccatccg tggggttaac tcgagtggag ccttggcaaa gttgcaggct
    30601 tttgacctga taaaggaaga cgggaaaaag gaagtattgg ggcgccccaa cctctatgtg
    30661 actacggatt atttcctaga ttacatgggg ataaaccatt tagaagaatt accagtgatt
    30721 gatgaacttg agattcaagc ccaagaaagc caattatttg gtgaaaggat agaagaagat
    30781 gagaatcaat aagtatattg cccacgcagg tgtggccagt aggagaaaag cagaagagct
    30841 gattaagcaa ggcttggtga cggttaacgg ccaagtggtg cgtgaactag caaccactat
    30901 caagtcaggc gacaaggtcg aagttgaagg tcaacctatc tacaacgaag aaaaggtcta
    30961 ctatctgctt aacaaaccac gcggtgtgat ttccagtgtg acagatgata agggtcgcaa
    31021 gacggttgtc gacctcttgc ccaatgtcaa agagcgtatt taccctgtgg gtcgtttgga
    31081 ctgggataca tcaggtgtct tgattttgac caatgatggg gactttacag acgagatgat
    31141 tcaccctcgt aatgagattg acaaggttta tgtcgcgcgt gttaaaggtg tggccaataa
    31201 ggacaatctc cgccccttga cccgtggtct tgagattgat ggtaagaaaa ccaagccagc
    31261 tgtttatgaa attctcaaag tggacccagt caaaaatcgc tctgtggtgc agttgaccat
    31321 ccatgaaggg cgtaaccatc aggttaaaaa gatgtttgaa gctgttggtc tccaagtaga
    31381 taagttgtct cggactcgtt tcggacacct agacttgaca ggactccgtc caggagaatc
    31441 ccgtcgtctt aataaaaaag aaatcagcca actacacacc atggctgtaa ctaaaaaata
    31501 atgaaacgaa ttttaatagc gcctgtgcgc ttttaccaac gttttatctc accagtcttt
    31561 ccaccctctt gtcgctttga gctgacttgt tccaactaca tgattcaggc tattgaaaaa
    31621 catggtttta agggggtatt gatgggcttg gctcggattt tacgttgtca tccctggtcg
    31681 aaaacaggta aggaccccgt tccagaccac ttttccctta aacgaaatca agaaggggaa
    31741 tgaggtgggg taaatagatt tcaaaatgat aaaaacgcat cctatcaggt ttgagtaaac
    31801 ttgataggat gcgttttaga atgtcaaaat tttatactct tcgaaaatct cttcaaaccg
    31861 cgtcagcttt catctgcaac ctcaaaacag tgttttgagc aacctgcggc tagtttccta
    31921 gtttgctctt tgattttcat tgagtattaa attgagtttg aagtggctta tttcaaagct
    31981 ttttgtatgt cttcaatcat gagttttgtt gattcaagtc cgcctccgct tagataccag
    32041 aggtctggtg ttagttggat aatcttacca tttttagcag caggtgtttc agcgataagg
    32101 gcattttcta ggacaccgtc gttgctagag ttgtccccac cgatggcaag ggtacggttg
    32161 atgacaaaga ggatgtcagg gttgatttct ttgacacttt caaagctgac ttcttgtccg
    32221 tggcgtgagt cttcaaattt tgtatcagtt ggtttgaatt tcaaggtttg gtacaagaaa
    32281 gagaaacgag atttggcacc aaaggctgcc atttttcctt cattaaggag gatcgcaagg
    32341 gcttttttgt cagagctttc atttttagta gcgacttctt ggatgctctt gtctagcttg
    32401 gccaattctt ccttggcttt ctgtgtacca gtttcgccga aggcacttgc taaggattcg
    32461 atattagcct tggtagaagt ccagtagtcg tccttgcttg cttggaagag aacggttggg
    32521 gcgatttctt tgaatttgtc tacgaatttt tgtgtacgtg gtgaagcgat aatcaaatca
    32581 ggctcaaggg cggcgatagc ttctaaatca ggttctttca tagaaccaac atttttgaca
    32641 gttcccacta ggtcttttag ataagtcgga acagtttttg taggcattcc gacgatattt
    32701 ttttcaaatc ctaaagcgcg aatagtatcc gcagcgccga ggtcaaaggt cacaatcttt
    32761 tcaggaactt tggaaagttt gacctcggcc agtgaacttt taatggttac ctctgttgga
    32821 gcagagctac tggtctctgt ctgactagtg cttgagtttg tactacatgc accaagtagg
    32881 agcaagaagc tggccactag ggcagtgaaa taaagtttaa gggatgtttt cataatttct
    32941 cctctttaaa atgtgataac gatttaggga gtctcttgat cttattgact aagagactga
    33001 aggttctcta acttgagctt ttatgttact agctatagat acagatcttt ttgtcattga
    33061 tatcagctag cgtgatggga atctcataaa gttgactgag caggtccgcc tgcatgattt
    33121 gatcggttct tcccttgcta aagacctggc cgtccttgaa ggcgacaatt tcatctgcat
    33181 actgactggc tatgttgata tcgtggagga cgatgataat ggtcttgccg agttcctcca
    33241 ccagtcgtcg aagaatctgc atcatgctga cgctttgctt gatatcgaga ttgttgagtg
    33301 gttcgtccag caagataaag tccgtatcct gggccagtac catagcgata aagacgcgct
    33361 ggagttgccc ccctgacagg ctattgatgt agcggtcttt taagttggtc agttccaaat
    33421 agttcagagt ttctcggatt ttttcccagt cttctgatct aagtcgacct cggctgtagg
    33481 gaaaacgtcc aaaactgacc agttcttcaa cagtcaattt ggcttggtaa ttgattttct
    33541 gttttaggat ggttagttct tgggccagtt cttgcgaatt ccagctctcg atttcacgtc
    33601 ctttgatact gagaactccc tgatctttct tggttagtct gctcatgatg gagaggagag
    33661 tcgattttcc agcaccattt ggaccaataa aggctgtcag tttttgagga ctgacttcaa
    33721 gcgaaatgcc ttgcaaaata tcctgttttt gaatggattt gtcaatgttt tccagtttca
    33781 ctgacgagcc ctcctatata gtaagataaa gaataagaag ccacccacac tctcaatgat
    33841 catactgata cgaatttcca gtgcaaagac tcgttcaatc aaggcttgcc ccaaggttaa
    33901 gctaataaat ccaaccagaa tggccactat aaagagtaac ttgtgctgat agtctttgac
    33961 aatcaggtag gtgaggttgg ccagcataaa gccgaagaag gccataggtc ctaccaaggc
    34021 agtggccgtt gaggtcaaaa gcacgattcc ccagaggagc tctttctgtt ctttttcaac
    34081 atcgagtccc aatatctgag ccgtttctct ttgcaggtgc aagacatcta gaacgactgc
    34141 ttttcgaaag aaaaagattg tcaaagcgag gatgatcaga gaaccgatgg ctaggatgga
    34201 agtgttgaga tgttgaaagg aggcaaaaag actattttgc agtttatcgt attcgtttgg
    34261 atccattagg acttgaagga aggtgctgat atttcgaaag agacttctga gcgctagaca
    34321 gatcagcagg atgaagacca ggtcttgctt catcagtgtc ttcaagtaac cttgtaaggc
    34381 gagaaagaag agggactgga caagaagtaa gactaggaat tctaagatag gggatttgcc
    34441 aagttgaaga aacttgcttt caaaaaccag tagtagggtt tgtagtagga cgtagaagga
    34501 ttcaattccc aaaatactag gcgtcaggaa gcgattttcc gtcagggttt gaaaactaat
    34561 ggtcgaaatc ccagtcgcga tggctaccaa gagataaacg atgatctttt gggaacgcaa
    34621 cttccaagca aaggctgaca agtgagtgat gggccaaaag tagagaagac aagctccgat
    34681 ggtaagaata atgagaatcc agaagagctt ggtatgtttg cttttagtct gcatcttttc
    34741 gtccccctct ccagagaagt aggataaaga cgagactacc gatgattcct agcaagagac
    34801 tgacagacaa ctcatagggc ctaatcagaa ctcgggatag gatatcgcaa gccagaacta
    34861 gattggcacc aaccagtgcg accatgagtt tggtttgact tagattatct ccatagcgct
    34921 tgcgaacaag attgggaacg ataactccga gaaatggtaa gccacccacg gtaatcatgg
    34981 tgacgcttgt cgttagcgcc accagaaaga gggccagttt ttcaagtagg gagtaggaaa
    35041 tccccaaact ctcgctggtt tctttcccta gattcatgat ggtgaaggtt tgggataatt
    35101 tccaaacggt tatcaggatg atgaggccta agaagagcca ctcatactga tgggtctgaa
    35161 tcatggagaa ggagccctgg gtccaggcag tcatactctg aaccagattg aaacgatagg
    35221 cgataacttc tgtgactgag ccgataatcc cgctatagat gatcccaatc agaggcaaca
    35281 tccacctttc ctttacagta aaaatggtca taaaggctag gaagaagagg gtgaatacga
    35341 tggatgaaac aaaagcgaag agcatctttt gggtcagact agccgatgga aagacaaaaa
    35401 ggctcagcac cattcccagt ttggcggctt cagtcgttcc aactgtactc ggtgcagcaa
    35461 actgattttg ggtaatagtc tgcatgagaa ggcctgccat actcatacta gaggcagtca
    35521 ggagaatact gatagttctt gggagacggg actcttgaaa gaggagccag gtctgctggt
    35581 cgaaatcaaa tagctttccc catgaaaaat cactggtccc aatgctaata gagagaaaga
    35641 ctaggagtag aagtaagcca attaaataat gagaaagttt cataccccgt cctttcatgt
    35701 agatttggta tcgaaagata tctgcggata taaatgtaac attatttttc taatctgtca
    35761 ataaaatttc tgacaattta ataaatacaa caaggagaga gcaacaagac tttctccttt
    35821 gttatcctat tctaaaatgt ttttacctta atctgataaa ataatatctt cgagggagta
    35881 gctagccgtc caatcaagat attgtttagc ttttgaagca tctgctagga cactggctgg
    35941 gtcactagca cgtcgagcaa caatctcgtg tgggattttt taatttagta attcttcagc
    36001 agttttaaag atttctttga tagtatagcc ttttttagtt cctaagttaa agatttgaga
    36061 agaactgtct tcttgaaata ggtagttcat tcctttaaca tgagcctatg caaggtccaa
    36121 gacataaatg taatctcgaa tacatgaacc gtcacgtgta tcgtagtcat ctccaaatat
    36181 tttttaagct atcatgttgt cccaatgcgg tcttgttgat atttggaatg atgtgagttg
    36241 gatttttcac acgcagaccg tttgaagcat ccatttcagc cccagcaaca ttaaagtaac
    36301 ggaaaataac atatttccag tcgtagcgat tggccatcca gtaaatcatt cgttcgccca
    36361 tcagttttgt ctctgcataa gggttgacag ggtcgagcag ggtatcttca gtcaccggct
    36421 tgtcaataca gttatttcca tagagagaag cagtcgaaga gaacatgatt ttttgaatgc
    36481 caacttcaga taagactttg agaacttggt tcataccagc aacgttggca gtgaagtatt
    36541 tacttggatt ttcaatactt tcgctcacaa caatttcacc tgcacaatgg aggacagcat
    36601 caatctgatt ttcttctaag taagccttta aggcgctagc atcataaaca tccagttctt
    36661 taaagctagc acgactatcc acagccgctc gatttcctgt ggagagatta tcgaggacat
    36721 gcacctgata gccagcattt aaaagagctt taacggtatg ggagccaatg tagctagtcc
    36781 cacctgtaac aagaattgtt ttggtcatga ttttttcctt ttctagtttt gtactatagt
    36841 aaattgaaat aagatatgaa caactctatt aggaaagtca aattaatttc tagaaatgtt
    36901 ttagcagcta cagcgtacta ttccaaactc aaccaactat atatttaaag aaagaagaaa
    36961 gggaagtcaa ctattttctg taaatttcat gaaaaatcca aacaactttg atggtgtatt
    37021 gtttttttgt ttggaaataa atattcgagt taattttgga atgtttacta gattttgcac
    37081 tacatgcaag agaatactat ccttttctaa gatagagcag gactaagata ctaacttaga
    37141 aatccacctt cccactatcc ttctcctata aaaagtggta aaatggatga aagaaagaag
    37201 gaactgaaat gacaacatta ttttcaaaaa ttaaagaagt aacagaactt gctgcagtct
    37261 caggtcatga agcgcctgtc cgtgcttatc ttcgtgaaaa gttgacaccg catgtggatg
    37321 aagtggtgac agatggcttg ggtggtattt ttggtatcaa acattcagaa gctgtggatg
    37381 caccgcgcgt cttggtcgct tctcatatgg acgaagttgg ttttatggtc agcgaaatca
    37441 agccagatgg taccttccgt gtcgtagaaa tcggtggctg gaaccccatg gtggttagca
    37501 gccaacgttt caaactcttg actcgtgatg gtcatgaaat tcctgtgatt tcaggttctg
    37561 ttcctccgca tttgactcgt ggaaaggggg gaccaaccat gccagccatt gccgatatcg
    37621 tttttgatgg tggttttgcg gacaaggctg aggcagaaag ttttggcatc cgtcctggtg
    37681 ataccatcgt accagatagt tctgcaattt tgacagccaa tgaaaaaaat atcatctcaa
    37741 aagcttggga taaccgctac ggtgtcctca tggtaagcga gctagctgaa gctttatcag
    37801 gtcaaaaact cggcaatgaa ctctatctgg gttctaacgt ccaagaagaa gttggtctgc
    37861 gtggcgctca tacctctaca accaagtttg acccagaagt cttcctcgca gttgattgct
    37921 caccagcagg tgatgtctac ggtggtcaag gcaagattgg agatggaacc ttgattcgtt
    37981 tctatgatcc aggtcacttg cttctcccag ggatgaagga tttccttttg acaacggctg
    38041 aagaagctgg tatcaagtac caatactact gtggtaaagg cggaacagat gcaggtgcag
    38101 ctcatctgaa aaatggtggt gtcccatcaa caactatcgg tgtctgcgct cgttatatcc
    38161 attctcacca aaccctctat gcaatggatg acttcctaga agcgcaagct ttcttacaag
    38221 ccttggtgaa gaaattggat cgttcaacgg ttgatttgat taaacattat taaaccataa
    38281 gggaggtggt agggatggta gaaccaaacc tagaaagcct tataaaagat ctttacaatc
    38341 atgctcgaca tgatttgagt gaagatttag ttgctgctct cctagagact actaaaaaac
    38401 tgcctactac aaatgagcaa ttgcaggcag ttcgtctctc aggcctggtc aatcgtgaat
    38461 tgctcctaaa tcccaaacat ccagcacctg agttgctcaa cttggctcgc tttatcaaaa
    38521 gagaagaagc caagtacaga ggaactgcga cttctgcgct tatgtatgag gaacttttta
    38581 aaatgctttg attccattgt ggatcaaagc attttttata agacctatct cgtgagcgtt
    38641 caaatagtag taacaaggaa tcatgagaag tcagccgaga ccatagtagt gaagaaactt
    38701 ctgtaatgga agtggagtga agtgaggaat cgtcaaacgg taggggatag gctgtttgaa
    38761 gggtgctacg aaaaagatag ggtaaggtga aattatagcg gaatgaaata agatatgaac
    38821 aaattgatta ggaaaatcaa atgaatttat agaaatattt tagcagtcat aacgtcctat
    38881 tccagtttca aaatgttata aatacgaaca aattgattgg gaaattcaaa tcgctttcta
    38941 tcaatgtttt agaagataca gtgccctagt ctaacttcaa tatactataa aagaacagat
    39001 ggaagcaatt atgatttact tctatcttta aaataaatga tctgatagga aaaatgtgtc
    39061 ccctcataaa aaataggata gtacggatgg aaggcttttg tagactggag gacgaaggaa
    39121 tttagaaact ctcgttaaaa gttagttgag ccggagtatg gtggtgtgaa taattatcaa
    39181 aaattatttc caaatcgaaa tagttgacag ttagaacgat gagtgttaca attattttat
    39241 tcatttcgac atcgaaataa attggaggtg ttatgaaaga tagtcatttg ctagcccatc
    39301 atattcgttt gttgaatggg cggatttttc aaaagttact gagtcaagat cctgaggctc
    39361 tttatagggg tgaacagggc aagattttag cggttttatg gaatagtgaa actggctgcg
    39421 caactgcgac agatatcgcg cttgcgactg ggcttgcgaa taatacgctg acgactatga
    39481 taaaaaagct agaggaacaa aagcttgtaa ttgttagtcc gtgtggaaaa gacaagcgta
    39541 agaagtattt agttttaacg gagttaggca agtcccagaa agaagtgggg catcgtgtca
    39601 gtcagaaatt ggatactatc ttttacaaag gattttcaga ggaagaaatt caccaatttg
    39661 aaggttttca agaaagaatt ttggcgaatt tgaaagagaa gggaaatgag gtttagaata
    39721 tgtcacaaca agtgaaaaat gctcacaacc tatacatcca tgccattcaa gacggacgag
    39781 ttgctgaggc tcaagcccag tctgtagggg atacctatat ccaacattcg acaggtgttc
    39841 ctgacgggaa agaaggattt gcagtcttct ttgcagattt ctttgagcgt catccagagc
    39901 gtcagattaa gattgtccgc accattgagg atggcaatct ggtctttgtt catgttcatc
    39961 aatatctgaa tggtggagaa gctcaatggg tgacgacgga tactttccgt gcggatgaga
    40021 atggtcgtat tgttgagcat tgggatgtca ttgactacta tcgaacacct gaaaatgacc
    40081 aactagatca aatttttgga gattttgaaa tcaaggattt ggacaagaaa gcagaaaata
    40141 aaaagctggt tcgccgtttc ttgacagaaa ttttccaaaa tggggagcta gagcagtgga
    40201 gtgattatgt ggcagacgat ttgattcagc ataatcatga gattggacaa ggaagtgctg
    40261 cttataaaaa ctatgtggct gaatatagtg tcacttttga ctttgttttc caactcttag
    40321 gacaaggaaa ctatgtggtt agctatggtc agactcagat tgatggcgtt gcttatgccc
    40381 agtacgatat cttccgttta gagaacggga aaattgtgga gcattgggat aataaggaag
    40441 tcatgcctaa ggtagaagac ttgaccaatc gagggaagtt ttaaattgag gacaaagaat
    40501 gattgaatac aaaaatgtag cactgcgcta cacagaaaag gatgtcttga gagatgtcaa
    40561 cttacagatt gaggatgggg aatttatggt tttagtaggg ccttctgggt caggtaagac
    40621 gaccatgctc aagatgatta accgtctttt ggaaccaact gatggaaata tttatatgga
    40681 tgggaagcgc atcaaagact atgatgagcg tgaacttcgt ctttctactg gttatgtttt
    40741 acaggctatt gctctttttc caaatctaac agttgcggaa aatattgctc tcattcctga
    40801 aatgaagggg tggagcaagg aagaaattac gaagaaaaca gaagagcttt tggctaaggt
    40861 tggtttacca gtagccgagt atgggcatcg cttacctagt gaattatctg gtggagaaca
    40921 gcaacgggtc ggtattgtcc gagctatgat tggtcagccc aagattttcc tcatggatga
    40981 acccttttcg gccttggatg ctatttcgag aaaacagttg caggttctga caaaagaatt
    41041 gcataaagag tttgggatga caacgatttt tgtaacccat gatacggatg aagccttgaa
    41101 gttggcggac cgtattgctg tcttgcagga tggagaaatt cgccaggtag cgaatcccga
    41161 gacaatttta aaagcgcctg caacagactt tgtagcagac ttgtttggag gtagtgttca
    41221 tgactaattt aattgcaact tttcaggatc gttttagtga ttggttgaca gctctatctc
    41281 aacatttgca gttgtcactt ttgaccttgt tactagctat tttgcttgcg attcccttgg
    41341 ctgtttttct tcgctatcat gagaagctgg ccgactgggt cttgcagatt gcaggtattt
    41401 tccagaccat cccgtctctg gccttgttgg ggctctttat ccctttgatg ggaattggga
    41461 ccttgccggc tttgacagct ctagtgattt atgcgatttt ccctattttg caaaatacta
    41521 tcactgggct gaagggaatt gatccgaacc tgcaagaggc tgggattgcc tttgggatga
    41581 ccagatggga acgtctcaag aaatttgaaa ttccacttgc catgcctgtt atcatgtctg
    41641 ggattcggac ggcagctgtt ttgattatcg gtacggcaac cttggcggcc ttgattggag
    41701 cagggggact gggttccttt atcctgttgg gaattgaccg taataatgcc agtttgattt
    41761 tgattggggc actttcttct gcagtgcttg ctattgcctt taacttccta ctaaaagtaa
    41821 tggaaaaagc aaaattacgg acgattttct caggttttgc cttggtgacg gtattgctgg
    41881 gtctatctta tagtccagcc ctcttggttc aaaaagagaa agaaaacgtg attattgcag
    41941 ggaaaattgg tccagaacca gaaattttgg ctaatatgta taaactttta atagaagaaa
    42001 atacaagtct aacagcaacc gttaagccta actttgggaa aacaactttc ctttatgaag
    42061 cgttgaaaag cggagacatt gatatctatc ctgaatttac tggtacggtg actgaaagtt
    42121 tgcttcaacc atcacctaaa gtgagtcatg agccagagca ggtttatcag gtggcgcgtg
    42181 atggcattgc caaacaggat catctagcct atcttaaacc catgtcttat caaaatactt
    42241 atgctgtagc tgttccgaaa aagattgcgc aagaatatgg cttgaagacc atttcggatt
    42301 tgaaaaaagt ggaaggtcag ttgaaggcag gctttacact cgagtttaac gaccgtgaag
    42361 atggaaataa gggcttgcaa tcaatgtatg gtctcaatct caatgtttca accttggaac
    42421 ctgctcttcg ctatcaagcg attcagtcag gtgaaattca aattacagat gcctattcga
    42481 ctgatgcgga attggagcgt tatgatttac aggtcttgga agatgacaag caactcttcc
    42541 caccttatca aggggctcca ctcatgaaag aagctcttct caagaaacac ccagagttgg
    42601 aaagagttct taatacattg gctggtaaga ttacagaaag ccagatgagc cagctcaact
    42661 accaagtcgg tgttgaaggc aagtcagcaa agcaagtagc caaggagttt ctccaagaac
    42721 aaggtttgtt gaagaaatga tgggacagag actttaaaca tactgaactc aacttcctta
    42781 aacgactaga taaaagaatg ctcagacaat ttcgtctggg cttttttgat gtgagaatga
    42841 ctgaatgtca cttaaaatgg aaagaaagag aaaattttca tgattttcta aaattttact
    42901 gtaaagacag ttgactattc ataaaatagg tgtataatat tttgtgaact acttaacaaa
    42961 taagaggttt cagctcatgt cgactaaggt tagaaatctt gtgtataggc agttcattat
    43021 ctaatagagc gttgcgtccg aaagtctatc cagacacggc tctttaaaaa caaaaggaga
    43081 aatgatgcat acttatttgc aaaagaaaat tgaaaatatc aaaacaaccc taggtgaaat
    43141 gtcaggtggt taccgtcgta tggttgcggc tatggctgat ttaggatttt caggaactat
    43201 gaaggctatc tgggatgacc tctttgccca tcgtagtttt gcccagtgga tttatttgct
    43261 ggttttagga agttttcctc tctggctgga gttggtttac gaacatcgta ttgttgactg
    43321 gattgggatg atttgtagct tgacagggat tatctgtgta atctttgtat cggaaggtcg
    43381 agcaagtaat tatctttttg gcttgattaa ctctgttatt taccttattt tggccctaca
    43441 gaaaggcttt tatggtgagg tgctgacgac actttacttc acagtcatgc agccaattgg
    43501 acttctagtt tggatttatc aggcacagtt taagaaggaa aagcaggagt ttgtcgcgcg
    43561 taaactggac ggcaagggct ggacaaagta tctttccatt agtgtgcttt ggtggttggc
    43621 ctttggcttc atttatcagt ctattggtgc caatcgtccc tatcgtgatt caatcacaga
    43681 tgcaaccaat ggggtagggc aaatcctcat gacagctgtt taccgtgaac agtggatatt
    43741 ctgggcggct accaatgtct tttcaatcta tctctggtgg ggagaaagcc tgcaaattca
    43801 agggaaatat ctaatttatc tcattaacag tctagttggt tggtatcaat ggagcaaggc
    43861 agctaagcag aatactgatt tacttaacta ggaaaagatg tttgaaagtg ctgttttgag
    43921 atttcgatta aaacagatat agttgataat caaggattta tagtatgaaa aagaggatcg
    43981 gcgggtcctc ttttgttgtt gaaaagataa aaaactcagt aatctagaaa taagacaact
    44041 gagctttact ctatattcaa tttttaggaa tgagaaggtc tagataaaat tggacaactt
    44101 cctggtctgt gaaatcttga ccttttttga gccaccaggt caatgtctcg ataaagttgg
    44161 acatgaccaa gtgttggagg taagaagtag gcagattagg gtgggcttct tttaaattat
    44221 cagctagcac ggaatagaca tggtgttcta gctctttatg gagttgacgg aggaagtagt
    44281 catttttgga aaatagcaga ctggtgatat ggtcttggtt tttatgaaaa tgcagaaaga
    44341 ggtgggcgag gtagtcctcg gttgaaatgg cttgctctct ttcaaaaaga tgatggaaga
    44401 ggtagcggca gagctggtcc agaagaagct ccttactctc atagtgacag taaaaggtgg
    44461 atcgtcccac atctgcgaga tcaatgatat cctgaacagt agtggcctcg tagcccttag
    44521 cattcaaaag ttgtataaaa gcttgataga tggctttttt ggttttgctg atacggcggt
    44581 caatgttagt catatggaca cttgaggcaa attgttcaga actgaataaa gctgacgttt
    44641 tgcttctatc ctttctttga gttttagtgg ataatgataa tgaacaaggt gttcataaat
    44701 ctattataac aaaggaatga gaaatatgaa ggcaaaatat gctgtttggg tggctttttt
    44761 cttaaatttg acttatgcca ttgttgagtt tattgcaggt ggagtatttg gttctagcgc
    44821 tgttcttgct gactctgtgc atgacttggg agatgcgatt gcaattggaa tatcagcttt
    44881 tctagaaaca atctccaatc gtgaagaaga caatcagtac accttgggct ataagcggtt
    44941 tagcctgcta ggagccttgg taacagctgt gattctcgta acgggctctg ttctagtcat
    45001 tttggaaaat gtcacgaaga ttttgcatcc gcaaccagtc aatgatgagg ggattctctg
    45061 gttaggaatt attgcgatta ctatcaatct gttagcgagt ctggtggttg gtaagggaaa
    45121 gacaaagaat gagtctattc tgaatctgca ttttctggaa gatacgctag ggtgggtagc
    45181 tgttatcctg atggcgattg ttcttcgatt tacggactgg tatatcctag atcctctttt
    45241 gtcccttgtc atttctttct ttattctttc aaaagccctt tcacgttttt ggtctacact
    45301 caagattttc ttggatgctg tgccagaagg tcttgatatc aagcaagtaa agagtggcct
    45361 ggaacgattg gataatgtgg ccagccttaa tcagcttaat ctctggacta tggatgcttt
    45421 ggaaaaaaat gccattgtcc atgtttgtct aaaagaaatg gaacatatgg aaacttgtaa
    45481 agagtctatt cgaattttcc taaaagattg tggttttcaa aatattacca ttgaaattga
    45541 tgctgaccta gaaactcatc aaactcataa gcgaaaggtg tgtgacttgg aacggagtta
    45601 tgagcatcaa cattagaaaa aagtgaaaaa tacttgggta ctatcttatt tggaatagag
    45661 taatttcttt attatttaaa tatttcaaaa attggtaaga gaagagcatt gtataaactc
    45721 cagatatatg attgttaatg ataaaaattt ttcgattaga tacaaaatgc ttgacttgga
    45781 gtcaactcaa agttatataa taagataagt gagttagaat agcgtgaact cagtgaatga
    45841 aatgagagga ggttagcgtg tgaatattaa atctgccagt gatttgttgg gaatttcagc
    45901 ggatacgatt cggtattatg aacgggttgg tcttgtgcca ccgattactc gtactgctac
    45961 tgggattcgt gattttcaag atcaggatat cgaagcgctg gaatttatta agtgttttcg
    46021 ttcggcgggt gtctctgtag atagtttagt tgactatatg tcgctctacc aaaagggaga
    46081 tgaaacgaga gaggagaggc ttggtatttt agaagaggaa aagcaaaaat tagaggagcg
    46141 cttgtctcag ctacagacag ctttaaatcg tttaaatctc aaaattaaac tttataagga
    46201 aggaaaattt taaatgaaat cagcagtata tacaaaggca ggtcaggttg gacttgctag
    46261 cattgaacgt ccgcaaataa tagaagcgga tgatgtgatt attcgtgtgg ttcgtgcgtg
    46321 cgtttgtggt tcagatttat ggaggtaccg taatccagaa acgaaagctg gacacaaaaa
    46381 tagtggacac gaagcgattg ggattgttga agaagctggg gaagccatta cgacggtgaa
    46441 accaggtgat tttgtgattg tcccttttac acatggatgt ggtgagtgtg atgcctgtct
    46501 tgctggattt gacggttctt gcgacaatca tattggcaat aatttggggg gtgattttca
    46561 ggcagaatat attcgcttcc actatgcaaa ctgggcgctg gttaaaatcc ctggtcaacc
    46621 ttctgactat acagaaggga tgctcaagtc ccttttgact cttgcagatg tcatgccgac
    46681 aggctatcat gcggcgcgtg ttgcaaatgt tcaaaaaggg gacaaggttg ttgttatcgg
    46741 tgatggggct gttggtcaat gtgctgtcat cgcggctaag atgcgtggag catcacaaat
    46801 tatccttatg agccgtcatg aagaccgtca aaagatggct atggagtcag gtgcgacagc
    46861 tgttgttgca gaacgtggtc aagaaggaat taccaaggtg cgtgaaatcc tcggtggagg
    46921 agcagatgca gcatttgaat gtgttggtac ggaggctgct atagaacagg cgctaggtgt
    46981 tcttcataat ggagggcgta tgggctttgt aggagtccca cactataata atcgtgctct
    47041 tggttcgaca tttatgcaaa atatctctgt agcaggtggg gcagcttctg ctacaacata
    47101 cgataagcaa tttttactaa aagccgtcct tgatggtgat atcaatccag gtcgcgtctt
    47161 tacttcaagt tataaactgg aagatatcga ccaagcctac aaagatatgg atgaacgtaa
    47221 gaccattaag tctatgattg taatcgaata aaaaacgaat aggagttcta aaactcctat
    47281 tcgtttttta tgttatccta ttcttgattt agggtacttt ctcttaatgt cagtctggtt
    47341 cccagcatgg tcaggctagg gattttccga ccgtggagga cttccttgtt aagaatatcc
    47401 atacctgctc ggcccatttc ttcagtataa actgtaatac tagagagggg aggatagacc
    47461 tgtttggtca gactagtgtc gttaaaggaa atgaggctga cgcgatctgg caggttgatt
    47521 ccagcttctt ggagggcacg gagggcaccg atagctaaac tatcgctggc tgcgaaaaat
    47581 gctggcggaa gttggtctcc caagctctga atggcctcct tcattaagtc atagccagac
    47641 tgggcagtaa atcttccttg aaagaccagt tcatcatgat agattcccct cgcttgactg
    47701 tagtttctga aattttccag ccgcttatcc tcaatgattt cttcttggtc tgttgtttct
    47761 tcaaggcctg ttagaatccc gatacggtcc attccttggc tgaggaaata atcgacaacc
    47821 tgtttcatag cagtgtaaaa atccgtgata atacaggtat gtcccaggga aagtgtatcg
    47881 ctgtctagaa atacaagagg cttttggtat tcttcaaagg cagaaatctg agctcgacta
    47941 aactttccga tgcagagaat cccaatcact tcctcgctta gggtaaaagg gtggtcatta
    48001 aaatagcgca agatatcgta gtccaactct tgggctcttt tttctattcc taggcgaatc
    48061 tggtagtagt agaggtcgtc tagctcccct tgttcgctga cccattgaat aatggcaatc
    48121 ttttgcttgg gtttatggga ctcgcctgtc ttgaggtgct tggtgtagcc cagctcttca
    48181 gcaacggtta aaatacggtg tctggtttct tctgtaacag ataggctctg gtcgcggttg
    48241 agaacacggg atacggtcgc gatagagaca gaggctagct gtgcaatgtc ttttaaggta
    48301 gccataaatc ctccttgatt aggttagtat atcatatttt tctgcttttt actgatattt
    48361 tagtaaaatt ttagtaaaaa ggattgacct tgggaaatcc cttggataca atagaagaaa
    48421 acgattacac gttaaggtgg cttaacggac agtcaaagga gaaatcatat gacacaacat
    48481 cttactgctg aaactcttcg caaagacttt cttgctgttt ttggtcaaga agcagaccaa
    48541 accttctttt caccaggtcg tatcaatttg attggtgaac acacagacta caacggtggg
    48601 cacgtttttc cagctgctat ttccttggga acttatggtg cagctcgcaa gcgtgaagac
    48661 caagttttac gtttctactc agctaacttt gaggacaagg gcattatcga agtgcctctc
    48721 gctgacctca agtttgaaaa agagcacaac tggaccaatt atccaaaagg tgtccttcat
    48781 ttcttgcaag aagctgggca cgtgattgac aaaggttttg atttttatgt ttatgggaat
    48841 ataccaaatg gtgctggttt gtcttcttca gcatccttgg agctcttgac aggagtcgtg
    48901 gcagagcatc tctttgattt aaaattagag cgtctcgatt tggttaaaat cggaaaacaa
    48961 acagaaaaca actttatcgg agtcaactct ggtatcatgg accagtttgc tattggtatg
    49021 ggggctgatc aacgtgctat ttaccttgat accaacacct tagagtatga tttggtgcca
    49081 cttgatttga aggacaatgt cgttgttatc atgaacacca acaaacgccg tgaattggcg
    49141 gactctaaat acaatgaacg tcgtgctgag tgtgaaaaag cagtggaaga attgcaagtt
    49201 gccttggata ttcagaccct gggtgaattg gacgagtggg ccgttgacca atatagctat
    49261 ttgattaaag atgaaaatcg tttgaaacgt gctcgccatg ctgtgcttga aaaccaacgt
    49321 acccttaaag ctcaagcagc ccttcaagca ggtgatttgg aaacatttgg tcgtttgatg
    49381 aatgcgtcac acgtttctct ggagcatgat tatgaagtaa ctggtttgga attagatacc
    49441 cttgttcaca cagcttgggc acaagaagga gttctcggtg ctcgtatgac aggggctggt
    49501 tttggtggct gtgccattgc cttggttcaa aaagatactg ttgaggcctt taaggaagct
    49561 gtaggcaaac actacgagga agtagttgga tacgctccaa gcttctatat cgctgaagtt
    49621 gcaggtggca ctcgcgtcct tgactagtca aaaggaggct ctatagtgac cttagtagat
    49681 aaatttgtaa cacatgtcat ttctgaaagt tcatttgagg aaatggatcg aatctacctg
    49741 accaatcgtg ttttggcacg agtgggagaa ggtgttttgg aagttgagac caatctggat
    49801 aaattgattg acctcaagga ccagctagtt gaggaagccg ttcgattaga gacgattgag
    49861 gatagtcaga ctgcgcgtga aatccttggt actgaattga tggacttggt gactccttgt
    49921 ccgagtcagg tcaatcgtga cttctgggaa gcctatgcct actctcctga gcaagcgata
    49981 gaggattttt atcaactcag tcagaaaaat gactacatca aactcaaggc cattgctaaa
    50041 aatatcgctt atcgtgttcc atctgattat ggagaacttg aaattaccat caatctctct
    50101 aagcctgaaa aggatccgaa agagattgcg gcagccaagt tggtgcaagc tagtaattat
    50161 cctcagtgtc aactttgttt agagaatgag ggttaccatg gtcgggtcaa ccacccagct
    50221 cgcaccaacc accggattat ccgttttgaa atggttggtc aggaatgggg tttccagtat
    50281 tcgccctatg cttactttaa tgagcattgt atctttttag atggccagca tcgtcccatg
    50341 gccattagtc gtcagagttt tgaacgtctg ttggctatcg tagagcagtt tccgggatat
    50401 tttgctggat ctaatgccga cctgccgatt gtggggggct ctattctaac tcatgatcat
    50461 tatcagggag gccgtcacgt atttcctatg gaattggctc ccttgcaaaa gaccttccga
    50521 tttgctggtt ttgagcaggt caaggctgga attatcaagt ggccaatgtc tgtcctacgc
    50581 ttgacttcgg attccaaaga ggatttgatt aacttagctg ataagatttt ccaggaatgg
    50641 cgtcagtatt cagattctag tgtgcagatt ttggcagaga cagacgggac accgcatcac
    50701 accatcacac caatagcgcg taagcgtgat ggacagtttg agttggactt ggtcttgcga
    50761 gacaatcaga cttcagcaga gcatcctgat ggcatctatc atccccacaa ggatgtccaa
    50821 catatcaaga aggaaaatat cggcttgatt gaggtcatgg gcttggcaat cttgccacca
    50881 cgtctgaaag aagaagtgga gcaagtcgct agctatcttg taggagaagc tgttacagtt
    50941 gccgattatc atcaggagtg ggcagaccaa ctcaaatccc aacatccaga cctaacggat
    51001 aaagaaaaag cccttgcaat cgtcaaggac tctgtgggtg ctatctttgt gcgtgtactt
    51061 gaggatgcag gagtctacaa gcagacagaa caagggcaga cagcctttat gcgctttgtg
    51121 gaacatgtcg gaatttcact agactaggag ctttctcctt gcacagtcct ataaaaagta
    51181 gtatcatagt gtcgtttgaa atatcaggag gaaacgatga aagattttca ttttgacgct
    51241 atatctgcct ttgaaaatta cgaaattgaa aaaatgagag atggtcacgt tgtggtgacg
    51301 accaaagtag tgaactcgtc gctcaattac tatggcaatg cccatggtgg ctatctattc
    51361 acgctatgtg accaaatcag tggtttggtg gttatctcgc tgggacttga tggggtgaca
    51421 ctccaatcct ctatcaacta ccttaaggca ggaaaactcg acgatgtatt gaccattaaa
    51481 ggagaatgtg tccatcaagg ccgtacaacc tgtgtgatgg atgtggatat cgccaatcaa
    51541 gagggcaaaa atgtctgtaa agcaaccttt accatgtttg tcacaggcca gcggtcagaa
    51601 gacagacagg taaggatata aagaaaggtg agtgggataa atttatctca ctcattttta
    51661 atttatgaga tatgttagaa ggaaatataa aagagagtga tgaaatacaa atgtaatagg
    51721 tacatatatg tggtatacta gttatagtag attttaatta cttatatcga gtgagttctc
    51781 atattagtga ggaattttta aatggaatta cactttaatt tagaattagt agaaacctat
    51841 aaaagtaata gccaaaaggc acgtatctta acggaggatt gggtttatcg tcagtcttat
    51901 tgccctaatt gtgggaacaa tcccttaaat cattttgaaa ataatcggcc tgtagcagat
    51961 ttttactgta atcattgtag tgaggagttt gaactaaaga gcaaaaaagg aaatttttca
    52021 tcaacaatca atgatggtgc ttatgcaacg atgatgaagc gtgtgcaggc agataataat
    52081 cctaatttct tttttttaac ttacacaaaa aattttgagg taaataactt tcttgtcctt
    52141 ccgaagcaat ttgttacacc gaaatcgatt attcaaagaa aaccacttgc accaactgct
    52201 agacgagcag gttggattgg ttgtaacatt gatttatcac aagtaccttc taaaggaagg
    52261 atatttcttg tgcaagatgg acaagttaga gatccagaaa aagttacaaa agaatttaag
    52321 caaggtttat ttttaaggaa gagctctctg tcatcaagag gttggacaat agaaattcta
    52381 aattgtatag ataagataga gggttcagaa tttacccttg aagatatgta tcgttttgaa
    52441 agtgacctaa aaaatatctt tgttaagaac aatcatatca aagaaaagat taggcaacag
    52501 cttcaaatat taagagacaa agaaataata gaatttaaag gtagaggaaa gtatcggaaa
    52561 ttatgaaaac gaaacaactt gttgcatcag aagaggtgta tgatttctta aaagtcatct
    52621 ggcctgatta tgaaactgaa agccgttacg ataacctaag tttaatcgtc tgtaccttat
    52681 cagatcccga ttgtgtgaga tggttatctg aaaatatgaa atttggtgac gaaaaacaac
    52741 tagctttgat gaaggaaaaa tatgggtggg aagtaggaga taaattgcca gagtggctac
    52801 atagctccta tcatagatta ttgttaatag gtgaattatt ggaaagcaat ctaaaactga
    52861 aaaagtatac agtagaaatt acagaaactt tatcacgttt agtaagtata gaggctgaaa
    52921 atccagatga agccgaacga cttgtaagag aaaagtataa gagttgtgaa attgttcttg
    52981 atgcagatga ttttcaggac tatgacacta gcatatatga ataggtagat gtttttattt
    53041 tgtcacacaa aaaagaggct cgcacctctt tttcttattt ctttttatga tttaatacgg
    53101 cattgaggac aatagcgagt aggctggcta cgacgattcc gtttgagaag aacatttgga
    53161 aggctgtcgg catgctgaca aagagattac tgttgttgag accgacacct gcagcgattg
    53221 aaacagctgc gataaggaag ttgtgttcat tgttagcaaa gtcaactcgg gcgaggattt
    53281 gcatcccttg aatagataca aaaccaaaca tcaccagcat ggcaccgccg aggacggagc
    53341 ttggaatgat ttgggcaagg gcaccaaact taggaagcag tccaaggaga accaggaaac
    53401 cagctgcgta gtagattggc aggcgttttt tgatgcctga caatttaacc aaaccaacgt
    53461 tttgtgaaaa tccggtgtaa gggaaggtgt taaagattcc tccgagaagt acggccaaac
    53521 cttctgcgcg gtaaccgttg cgaaggcgcg tgctgtcgat tggatctttt gtgatatcag
    53581 acaaggctag ataaacacca gttgactcaa ccatagacac cgttgcgatg atacacatca
    53641 tgacaataga tgagatttca aaggttggca tcccaaagta gagtggaatt gggacatgga
    53701 caagtggagc taccgcaaca ggagagaagt ccaccaagcc catagtagca gcaatggcag
    53761 ttccaacaac cagaccaatc aaaatagaga tagacttgat aaatcctttg gtaaagatgt
    53821 tgatcaagag gataatcaga acagtaatag ctgaaagcaa gagactttga ccagttggct
    53881 ctggaacgtt atttcccata tttccaatag cgacagggat caaggttaaa ccaatcgtgg
    53941 taataacaga tcctgttacg atagatggga aaagattggc tacttttgag aagatgcctg
    54001 aaacaagaac cacgtaaatc ccagatgcga taagggcacc aaacatagcg ccactaccat
    54061 ggctttgccc aatcataatc aagggagcga ccgactggaa tgcaactcca agaacgactg
    54121 ggagtccaat cccaaagtat ttgttgagtt ggagttggag gaaggttgcc accccacaca
    54181 tgaagatatc tgtagaaata aggtaggtca actgctcagc tgaatagcca agggctgtcg
    54241 caatcatgat gggaaccagg atagatcctg agtacatggc tagtaagtgc tgcaagccca
    54301 gaacggctgc ttgcgagtgt ttttcttgag tttgcattag agatctgcct ccttaaatac
    54361 gacctgacca ttttcaaaac gatccaagcg agcaagtgat aggacagggt agcctgcttt
    54421 ttcaagcaaa tcacgaccat cttggaagga tttctcaatc acgataccga tagcttggac
    54481 tgtggcaccg gcctgttcga tgatttgaat caagccttta gcagcttggc cattagcaag
    54541 gaaatcgtcg ataatcaaaa ccttgtcctc tggtgagagg aattttccag cgatagaaac
    54601 agtgctggtc acctgcttgg taaaggagta gacttgagca gttaagatgc cttcgttcat
    54661 ggtgatgttc ttagcttttt tggcgaaaat catgggaacg tttaaggctt cagctgtaaa
    54721 aacggctggg gcaatacccg acgcttcaat ggttacgaca ttggtaatgc cagtagcagc
    54781 aaatttttcc gcaaaaacct taccaatctc tcgcatcaag ctaaagtcaa cttggtgggt
    54841 taaaaaggaa tctaccttga ggatgttatc acccaagata tgcccatcct tgaggatgcg
    54901 ctcttctaat aatttcataa gacctcctaa agtctaaaag ttaatttact tgttgtttaa
    54961 atgtttctat agtgatccct tttgctaata ctatatattt gataaaacta ttacgagcga
    55021 agcgagtctt atcaaatatt tcccgttgta gtggtatcat agacaataat cttgttattg
    55081 tctatgacgg gatttttgag agtaaaatag ttcggggaac tattttagcc taagcctaga
    55141 aatgaaagag ctaggggctc aaaaattagg gatgaaattc cctggatttc tgaaattatt
    55201 cacaggataa tttcacctcc cgtccgcact aattaaggga aatattaaaa atattcaaaa
    55261 aagacctact taatctctaa gtaagtcccc taaatagaca tggcaaaaac ggccatatct
    55321 cactgctgac ttacttattg ttaggtgttc cggcaccttg tagaaacgtc gtgccaattc
    55381 acgacataaa caagtaaaac gatattcaat tttaaatagg cttgagccaa tgtttttatt
    55441 ttacactaaa taactttaga aatcaactat tttgttagtg ttttggttta aaaaacgaac
    55501 aaacagaaga gagggtgaac aaaaactcca ttgtaaacta acatttatac taaatgaaaa
    55561 tcaaagagca aactaggaag ctatccacaa cctcaaaaca ctgttttgag gttgtggata
    55621 gaattgacag agtcagtatc atatacctac ggtaaggcga cgttgacgtg gcttgaagag
    55681 attttcgaag agtattagaa gatttttcca tcataaaagg catactatca agtttttaga
    55741 tacctgacaa tatgcctttt tctaacttta aagacttttc ccaattttta ttattctact
    55801 cgctaaatct taaaaaatag ccatctggat ccaaaactgc aaatttatga ggatagatat
    55861 agggatcact gacacgaaac tttcttttgg tcaagagacg ataaatagga tagtttgcct
    55921 ccatcacttt ttgatagagt tttggaacat cctttatgcc aaaggagaga ttgactccac
    55981 gaccaaaggg gtaggtcagt tcagctagtt gatcctttgt tccctcctct aacattagtt
    56041 gacactcttc aagagaaaga gaaagttttc ttctggacgt tagtattcaa tcctaaaacc
    56101 cagtaaacca cagtagaagg accgggactg ttcgatattc gatacaagaa actcgggaat
    56161 gaccgcattg tagtccatat agaaaatcct tacaagtcaa tttccaagac aatcggtgta
    56221 tggtcttggc gagcacctga gtcaatcata tcagatttag tgaccttgtc agcgatacgg
    56281 ttacttgtga gccagtagtc gattctccag cctgtattgt tgattttaga agttttgctg
    56341 cgttgtgccc accaagtgta gcgttcagga acatcgccat gaacatggcg gaaggtgtct
    56401 gtaaatccag ttgccaaaag gttggtaaat ccagcacgtt cctcgtcagt aaatccaggt
    56461 gaacggcggt tgctagcagg atttgcaagg tcgatttcat tgtgggctac gttgtagtca
    56521 ccggtcgcaa ggactggttt ttctttgtct agttcagcca aatactcagc atatttaaca
    56581 tcccagactt ggcgttcttc caagcgtttg agaccgtcac cagcgtttgg agtgtaaact
    56641 tgggttacga aaaatgcatc aaattctaga gtgatgatac ggccttccaa gtccatggta
    56701 gaaggggcac cgatttctgg aaaactgatc gtaggcgtaa gttctttctt ataaaggaac
    56761 atggttccag catagccttt acgggcaggc tcttgggaag agcgccatgt gttttcgtag
    56821 cctgggaaga gttcttctaa aatttccacg tgtttctttg taggtccttt ggcagaaagc
    56881 ttggtttctt ggatagcaat gatatcagca ttttcagcga ccaaggtttg taggacttct
    56941 tgggacaatt tggcacgagc tgagtcacta gttagggcag cgtttaggga atcaatattc
    57001 catgagataa gtttcataaa gttacctttt tcattcagat tatagatttt attataccaa
    57061 aaaaagatct atttccccaa cgtatggttt gaaaaattac tctctttcgt ttataattaa
    57121 gaatgatttt atgaaaggga gtgaaaatat atgaaattct actcttatga ctatgtactc
    57181 agccaaatcg gtcagcaaaa tggtatcatg gttggctttg ggattgttct attagctgtg
    57241 acagtttttt tgctttcaag gcataccatg ataaaaaggg aaccgaattt cgtgagttgg
    57301 tcatgatttc agctctggcc ttatttagct ctgcttttgg tcagcatcac gacttatcaa
    57361 aacaatcaag tttctaacaa taaatttcaa acttcacttc atttcatcga ggttgtttcc
    57421 aaagatttgg gagtagacaa gtcagaagtc tatgttaata cttccacaaa cacagatggc
    57481 gcacttatca aggtgggaga tcgctattat cgtgccctaa acggaagtga gccagacaag
    57541 tacctgttag agaaagtcga attgtataag acagacgcaa ttgaactggt ggatgtgaac
    57601 aaatgacact taattatatc gaaattttaa tcaaactggt cttgactctc aaatggctca
    57661 acaacaatgt tcactttgtg aaacgtttga ttgatggtaa gccaactctc cttatcaaaa
    57721 atgggaatat tgacccagaa gcctgtcgtt cagttggttt gtctgcatcg gatgtagccc
    57781 tcaaacttcg tagccaaggg attttccaga tgaagcaagt caaacgagct gtgcaagagc
    57841 aaaatgggca acttatcgtt gtgcaaatgg gagatgaaaa tcctaagtat ccagttgtga
    57901 ctgacggtgt gattcaagta gatgtcttgg aatcgattgg tcgtagcgaa gagtggttgc
    57961 ttgataacct cagtaaacaa gggcatgaca atgtagccaa tatctttatt gctgaatatg
    58021 acaagggtgc tgttacagtc gtaacttatg aaaaagaaaa acctggggtc ttgtactctt
    58081 cgaaaatctc ttcaaaccgc gtcaacgtcg ccttgccgta tgtaggttac tgacttcgtc
    58141 agttctatct acaacctcaa agcagtgctt tgagcagcct gcggctagtt tcctagtttg
    58201 ctctttgatt ttcattgagt attggcctca ggtttccatt tgcaatcaga aagggatttt
    58261 atgtccatta ttcaaaaact ttggtggttt ttcaagttag aaaaacgccg ttatctagtc
    58321 ggaattgtgg ccctggtctt ggtttccgtc ctcaatctca ttcctcctat ggttatgggg
    58381 cgggttattg atgccatcac atcggggcaa ttaacccagc aggacctcct tcttagccta
    58441 ttttacttgc tacttgcagc ctttggtatg tactatttgc gctatgtgtg gcgtatgtat
    58501 atccttggga cctcttattg cttgggacag atcatgcggt ctcgcttgtt taagcatttc
    58561 acaaaaatgt cgtcagcctt ttatcaaacc tatcggacgg gtgatctgat ggcacacgca
    58621 accaatgata tcaatgcctt gactcgttta gcaggtggcg gtgtcatgtc tgcggtggat
    58681 gcctctatca cggctctggt gactttgttg accatgctct ttagcatctc atggcagatg
    58741 actcttgttg ccattctccc cctacctttc atggcctatg cgactagtcg cctagggaga
    58801 aagactcata aggcctttgg cgaatcccaa gctgcttttt ctgaactcaa taacaaggta
    58861 caggagtccg tatcaggtat caaagtgacc aagtctttcg gttatcaggc agacgagttg
    58921 aagtcttttc aggcagtcaa tgaattaacc ttccaaaaga acctgcaaac catgaaatat
    58981 gatagtctct ttgaccctat ggttctcttg tttgttggtt cgtcctatgt tttaacgctt
    59041 ttggttggct ccttggtggt tcaggaaggg cagattacag ttgggaatct agtcaccttt
    59101 atcagctatt tggatatgct ggtctggcct cttatggcca tcggcttcct ctttaatact
    59161 actcagcgag ggaaggtttc ttaccagcgg attgaaaatc ttttgtctca ggaatctcct
    59221 gtacaagacc cggagtttcc tctggatggt attgaaaatg ggcgtttgga gtatgccatt
    59281 gacagctttg cttttgaaaa tgaggaaaca ctgacggata ttcactttag tttggcaaaa
    59341 gggcaaacac tgggcttggt tgggcagaca ggctctggga aaacgtcctt aatcaagctc
    59401 ctcttgcgtg aatacgatgt ggataagggc gccatttatc taaacggtca cgatattcgg
    59461 gactatcgtc tgacagacct tcgcagtctc atgggctatg ttcctcagga ccagtttctt
    59521 tttgcgactt caatcctaga caatatccgc tttggcaatc ctaacttgcc cctttcagcg
    59581 gtcgaggaag ctactaagct agcccgagtt taccaagata ttgtagacat gcctcaagga
    59641 tttgatacgc tgattggtga aaaaggagtc agtctttctg gtggtcaaaa gcaacggttg
    59701 gctatgagtc gggctatgat tttagaccct gatatcttga ttttggatga ttccttatcc
    59761 gccgtagatg ccaagacaga gtatgcgatt atcgacaacc tcaaggagac gcgaaaggac
    59821 aagacaacca ttatcactgc ccatcgcctg agtgcagttg tccatgcaga tttgatttta
    59881 gtcctgcaaa atggtcaaat tatcgaacga ggcaggcacg aagacttgct agctttggat
    59941 ggctggtatg cccaaaccta ccagtctcag cagctggaaa tgaagggaga agaagatgca
    60001 gaataaacaa gaacaatgga ctgtattgaa gcgcttgatg tcctatctca agccttatgg
    60061 actccttacc tttttggcac tcagttttct cctagcgacg acggtcatta aaagtgtcat
    60121 tccccttgtg gcttcccact ttatcgacca gtatctcagc aatcttaacc aactagccgt
    60181 gaccgttttg ctggtctact atggtctcta catcctacaa actgtagttc agtatgtcgg
    60241 caatcttctc tttgcgcgcg tgtcttacag tattgttagg gatattcgtc gggatgcctt
    60301 tgccaatatg gagaaactgg gcatgtctta ctttgacaag acgccagcag gttctatcgt
    60361 ttctcgtttg accaacgata ccgagacgat tagtgatatg ttttctggga ttttatccag
    60421 ctttatctca gcagttttta tctttctgac aaccctttat accatgttgg tgctggattt
    60481 tcgtttgaca gcattagtct tgctctttct ccccttgatt ttccttttgg tcaatctcta
    60541 tcgaaaaaag tcagtgaaaa tcatcgagaa aaccagaagt ctcttgtcag atatcaatag
    60601 taagctggca gagaatatcg agggaatcag gattattcag gcttttaatc aagagaagcg
    60661 cctgcaggca gaatttgatg aaatcaacca agagcacttg gcctatgcca accgttctgt
    60721 agccttggat gccctctttt tgagacctgc catgagtttg ttgaaacttc taggttatgc
    60781 tgtcttgatg acctattttg gctatcgtgg tctttctatc gggataacgg ccgggaccat
    60841 gtatgctttt atccagtaca tcaaccgcct ctttgaccct ttgattgagg tgatgcaaaa
    60901 cttttcaaca ctgcaaacgt ctatggtttc tgcaggccgt gtctttgcct taatcgatga
    60961 gaggacctat gagccccttc aagaaaatgg gcaagccaaa gtcaaagaag gcaatatccg
    61021 ttttgaacat gtgtgtttct cgtatgacgg taaacatccg attctggatg acatttcttt
    61081 ctctgttaat aagggtgaaa ccattgcctt tgtaggtcat acaggttcag ggaaatcgtc
    61141 tattatcaat gtcctcatgc gcttttatga attccagtca gggagagttc tcttggatga
    61201 tgtggatatc agggatttca gtcaagaaga gctgagaaaa aacatcggtt tggttttaca
    61261 ggaacccttc ctctatcatg gaactattaa gtccaatatc gccatgtacc aagaaatcag
    61321 tgatgagcag gttcaggctg cggcagcctt tgtggatgca gattccttta ttcaagaact
    61381 tcctcagggg tacgactccc ctgtttccga gcgtggttcg agcttctcta ctgggcagcg
    61441 ccagcttctt gcctttgcta gaacagtcgc cagccagcct aaaatcctga ttttggatga
    61501 agcgacagcc aatattgact ctgaaacaga aagtttggtt caagcttctc tggcgaagat
    61561 gagacagggc cgaacaacta ttgctatcgc tcaccgcctt tctactattc aagacgccaa
    61621 ctgcatctat gtcttggata agggacgcat tatcgagagt ggaacccatg aggaactctt
    61681 gactctggga ggaacctatc acaagatgta tagtttgcag gcaggggcca tggcctatac
    61741 tctttgaaaa tctctttaaa ccatgtcagc tttatctgca atctcaaagc tgtactttga
    61801 ttttcattga gtactagaag gaaatccttc aaattacaga tttctttcac cgccttttcc
    61861 attttgtggt ataatgaaaa atgttgacaa atagtataat aaaaacaaag gagaacagca
    61921 tgctgaaatg ggaagacttg cctgtggaaa tgaaatcaag cgaggttgag tcttactacc
    61981 agcttgtctc taaaaggaag ggttcgctga ttttcaagcg ttgcttggac tgggttttgg
    62041 ccttggtctt actggttcta acttctccca tctttctcat cttgagcatt tggatcaagt
    62101 tggatagcaa ggggccagtg atttacaagc aagagcgtgt gacccagtac aaccgtcggt
    62161 tcaagatttg gaagttccgt accatggtga cggatgcgga taaaaaagga agtctggtga
    62221 cttctgctaa cgatagccgt attaccaagg ttggaaattt catccgacgt gtccgtttgg
    62281 acgaactgcc tcagttggtc aatgtcctta aaggtgagat gtcctttgtc ggtacacgac
    62341 ctgaagtgcc acgttataca gagcagtata gccctgaaat gatggcaacc ttgctcttgc
    62401 aagcaggaat tacctctcca gccagcatca actacaagga tgaggacacc atcatcagtc
    62461 aaatgacgga gaaaggtctg tcagttgatc aggcctatgt ggagcatgtt cttcctgaaa
    62521 agatgcgcta taacctcgcc tatctccgag agtttagttt ctttggggac atcaaaatca
    62581 tgtttcaaac cgtgtttgag gtactaaaat aaagtagtca taagaaaatg agtacagata
    62641 aaaggagcaa atcaatgcca aattacaata ttccattttc accgcctgat atcacagaag
    62701 cagaaattgc tgaagtagcg gataccctgc gttctggttg gatcacaaca ggtcctaaaa
    62761 caaaagaact ggagcgccgc ttgtctcttt acacacagac acctaagact gtttgtctca
    62821 actctgcgac agccgctctg gagttgattt tacgcgtttt ggaagtggga cctggtgatg
    62881 aagtcatagt tccagccatg acctatacgg cttcatgtag tgtcattacg cacgtgggag
    62941 caacccctgt catggtggat atccaagcag atacgtttga gatggactat gacctgcttg
    63001 agcaagctat cactgagaaa actaaggtga ttatcccagt agagctcgca gggattgttt
    63061 gcgattatga ccgtttgttc caagtcgtgg agaaaaaacg tgacttcttt accgcttcaa
    63121 gcaagtggca aaaggccttt aaccgtattg tcattgtctc tgatagtgcc cacgctttgg
    63181 gatctactta taaaggacaa ccttctggtt ctatcgctga ttttacttcc ttctcattcc
    63241 atgccgttaa gaactttaca acggcagaag gtggaagtgc gacttggaaa gccaatccag
    63301 tgattgatga cgaagagatg tacaaggaat tccaaatcct ttcccttcac gggcaaacta
    63361 aggatgctct tgccaagatg caactggggt catgggaata cgatatcgtt acaccagcct
    63421 ataagtgcaa catgaccgat atcatggctt cacttggttt ggtacaattg gaccgctatc
    63481 caagtttgtt gcaacgccgt aaggacattg tggaccgcta tgatagtggt tttgcaggtt
    63541 ctcgcatcca tcctttggca cacaagactg aaactgtcga atcttcacgc cacctctaca
    63601 tcacccgtgt agaaggagca agcctagaag aacgcaacct catcatccaa gaattggcta
    63661 aagcaggaat tgcaagtaat gttcactaca aaccgcttcc tctcttgaca gcctataaga
    63721 atcttggatt tgatatgacg aactatccta aggcctatgc cttctttgag aatgaaatta
    63781 ccctccctct tcatactaaa ttaagcgatg aagaagtaga ctatatcatt gagactttca
    63841 aaacagtttc tgaaaaagtg ctaactttat caaaaaaatg acaaactaca gtcaagcgaa
    63901 agtgatcctg tccctaaaaa gtctaattga gtgtaaaaac tgttgttttc aattgataat
    63961 agtttacacc tgtagttgag gcctctttct cctcagagag agaattttta taggattttc
    64021 ctttcttgtg ggagtcccgt ggtttgaaat aagatgtgag caatttggtg tagcatttag
    64081 aatccttact agacatcatt tagaaaatct agtgtcttgt tctagttttc aattcaccct
    64141 attttttgaa agacgtgagt ttccatgagt gagattgtgg aaactcgcgt cctttttttg
    64201 ttttcagaat attgttcaaa gttttgtgcc tgtctttcat gttctagtca ttcttttgca
    64261 tgatagaatt tataacatat tgatattata ataatgcaaa taccccatat gtttagtgat
    64321 gcttgctata catcattaga tctcctgcga gacaatctat aaaacacttg tctacgatta
    64381 cctatatgcc ctattccagt attttagaag cactgcatct atttttatcg aggttaaatc
    64441 tagcttttat agaaggtcta tttaagaaat atattgtagt gttttagttt caatccgcca
    64501 tatgagcgat attaaggtaa atatccctgg cgaatgcttg tatgacaagg tatttgttct
    64561 ttcatttata atttacaaca tatcaataaa tttaaatata gtaaatggga tattttatat
    64621 tcaagctaag aaagatagca tcacttttga atggaaggct aaagagcaaa ctaggaagtt
    64681 ggccatagat agctcaaaac cctgctttga ggttgtagat ataataaaat gaaataagaa
    64741 taggacaaat cgatcgggac agtcaaatcg atttctaaca atgttttaga agtagaggtg
    64801 tactatttta gtttcaattt attatagaac tgaccaagtc agtaacctag acttagggca
    64861 aggcggaact gacctagttt gaagagattt ccgaagagta taaattttaa tattttcttg
    64921 tgttattcct tgacaattca atttggaaaa tatatgataa agataatgac agcggtgtca
    64981 ttctatctgt tttaagaaaa gtaataatca attgttaaaa aatagtaaaa aaattggagg
    65041 ttctgatgaa atattttgtt cctaatgagg tattcagtat tcgtaaatta agggtgggga
    65101 cttgctcggt actattggca atttcaattt tgggaagcca aggtatttta tcggatgaag
    65161 ttgttactag ttcttcaccg atggctacaa aagagtcttc taatgcaatt actaatgatt
    65221 tagataattc accaactgtt aatcagaatc gttctgctga aatgattgcc tctaattcaa
    65281 ccactaatgg tttagataat tcgttaagtg ttaatagtat cagctctaat ggtactattc
    65341 gttccaattc acaattagac aacagaacag ttgaatctac agtaacatct actaataaaa
    65401 ataagagtta taaggaagat gttataagtg acagaattat caaaaaagaa tttgaagata
    65461 ctgctttaag tgtaaaagat tatggtgcgg taggtgatgg gattcatgat gatcgacaag
    65521 caattcaaga tgcaatagat gctgcagctc aagggctagg tggaggaaat gtatattttc
    65581 ctgaaggaac ttatttagta aaagaaattg tttttttaaa aggtcataca cacttagaat
    65641 tgaatgagaa agctacaatt ctaaatggta taaatattaa gaatcaccct tccattgttt
    65701 ttatgacagg tttatttacg gatgatggtg cgcaagtaga atggggccca acagaagata
    65761 ttagttattc tggtggtacg attgatatga acggtgcttt gaatgaagaa ggaactaaag
    65821 caaaaaatct accacttata aattcttcag gtgcatttgc tattgggaat tcaaataacg
    65881 taactataaa aaatgtaaca ttcaaggata gttatcaagg gcatgctatt caaattgcag
    65941 gttcgaaaaa tgtattagtt gataattctc gttttcttgg gcaagcctta cccaaaacga
    66001 tgaaggatgg gcaaatcata agtaaggaga gcattcagat tgaaccatta actagaaaag
    66061 gttttcctta tgccttgaat gatgatggga aaaaatctga aaatgtgact attcaaaatt
    66121 cctattttgg caaaagtgat aaatctgggg aattagtaac agcaattggc acacactatc
    66181 aaacattgtc gacacagaac ccctctaata ttaaaatttt aaataatcat tttgataaca
    66241 tgatgtatgc aggtgtacgt tttacaggat tcactgatgt attaatcaaa ggaaatcgct
    66301 ttgataagaa agttaaagga gagagtgtac attatcgaga aagcggagca gctttagtaa
    66361 atgcttatag ctataaaaac actaaagacc tattagattt aaataaacag gtggttatcg
    66421 ccgaaaatat atttaatatt gccgatccta aaacaaaagc gatacgagtt gcaaaagata
    66481 gtgcagaata tttaggaaaa gtatcagata ttactgtaac aaaaaatgta attaataata
    66541 attctaagga aacagaacaa ccaaatattg aattattacg agttagtgat aatttagtag
    66601 tctcagagaa tagtatattc gggggtaaag aaggaattgt tattgaggat tcaaagggta
    66661 aaataaccgt tttaaataac caattttata atttatccgg taagtatata tcattcatca
    66721 aatctaatgc aaatgggaaa gaacctgtta tacgtgatag cgatggtaat ttcaatattg
    66781 taacggagaa tgggctttac aaaattgtaa caaataattt aagtgataaa aacgaaaaag
    66841 aaaaaaacaa agaggaaaaa caatctaatt caaataatgt aattgatagt aaccagaaga
    66901 acggagagtt taactcaagt aaagataata gacaaatgaa tgacaagatc gacaataaac
    66961 aagataataa gacagaagaa gtaaactata aaatagttgg agatggcaga gaaactgaaa
    67021 atcatattaa taaatctaaa gaaatagtag atgtaaaaca aaaattacca aagactggtt
    67081 cgaataagat tatggaacta ttcttaacag tgacaggaat tggtttactt ttgacactaa
    67141 aagggttgaa gtattatggt aaagataaat aaaatttgtt cgatacaagg aagttccgta
    67201 gaaaatgagg atattgtagg ttcacaaaat cagtattttt ggattattgg tggagctaca
    67261 gatttatata attctaaaga ggagataggt tattcagtct cagaagttgt acatatttta
    67321 tcagaaagtt tgtcggttaa ttgtaaagaa tcaaaaactc ttaaacaaat atttgaaact
    67381 gctttactcg aggttaaaga tgaaatcggt ttaaactcat ataaattaac agagtatagt
    67441 aaaatgaaat aataatagga caaatcaatc aggacagtca aatcgatttc taacaatgtt
    67501 ttagaagtag aggtgtacta ttctagtttc aatatactat attatcgctt accaatattt
    67561 gctaaacttt cagaaaaaaa gttggagtat atgatgctag gtgactgcgt catgttagta
    67621 aacgaaatgg aaataactga tcatagagta gataacttat ttgaa
//
LOCUS       DAVLZS010000006        66000 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLZS010000006 DAVLZS010000000
VERSION     DAVLZS010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66000
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.006"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            84..491
                     /locus_tag="VYO88_000353"
     CDS             84..491
                     /locus_tag="VYO88_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1718520.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTTEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATPFKEVQKPLENFN
                     HIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            656..955
                     /locus_tag="VYO88_000354"
     CDS             656..955
                     /locus_tag="VYO88_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1718521.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VYO88_000355"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VYO88_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1718522.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
     gene            complement(2268..3995)
                     /gene="ezrA"
                     /locus_tag="VYO88_000356"
     CDS             complement(2268..3995)
                     /gene="ezrA"
                     /locus_tag="VYO88_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1718523.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4077..6023)
                     /gene="gyrB"
                     /locus_tag="VYO88_000357"
     CDS             complement(4077..6023)
                     /gene="gyrB"
                     /locus_tag="VYO88_000357"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1718524.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6038..6601)
                     /locus_tag="VYO88_000358"
     CDS             complement(6038..6601)
                     /locus_tag="VYO88_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1718525.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQT
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(6686..7240)
                     /locus_tag="VYO88_000359"
     CDS             complement(6686..7240)
                     /locus_tag="VYO88_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1718526.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDDVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(7251..8474)
                     /locus_tag="VYO88_000360"
     CDS             complement(7251..8474)
                     /locus_tag="VYO88_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1718527.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(8511..10961)
                     /locus_tag="VYO88_000361"
     CDS             complement(8511..10961)
                     /locus_tag="VYO88_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1718528.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11160..12089)
                     /locus_tag="VYO88_000362"
     CDS             complement(11160..12089)
                     /locus_tag="VYO88_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1718529.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            12229..12516
                     /locus_tag="VYO88_000363"
     CDS             12229..12516
                     /locus_tag="VYO88_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1718530.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(12550..13884)
                     /gene="ciaH"
                     /locus_tag="VYO88_000364"
     CDS             complement(12550..13884)
                     /gene="ciaH"
                     /locus_tag="VYO88_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1718531.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13874..14548)
                     /gene="ciaR"
                     /locus_tag="VYO88_000365"
     CDS             complement(13874..14548)
                     /gene="ciaR"
                     /locus_tag="VYO88_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1718532.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(14657..17203)
                     /locus_tag="VYO88_000366"
     CDS             complement(14657..17203)
                     /locus_tag="VYO88_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1718533.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIAVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLETVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(17326..17766)
                     /locus_tag="VYO88_000367"
     CDS             complement(17326..17766)
                     /locus_tag="VYO88_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1718534.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(17741..18610)
                     /locus_tag="VYO88_000368"
     CDS             complement(17741..18610)
                     /locus_tag="VYO88_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV1718535.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(18652..19380)
                     /locus_tag="VYO88_000369"
     CDS             complement(18652..19380)
                     /locus_tag="VYO88_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1718536.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(19388..19867)
                     /locus_tag="VYO88_000370"
                     /pseudo
     CDS             complement(19388..19867)
                     /locus_tag="VYO88_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            complement(19878..20576)
                     /locus_tag="VYO88_000371"
     CDS             complement(19878..20576)
                     /locus_tag="VYO88_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1718537.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGFQVYGVDQGENPLLEGDF
                     HFLQRDLTLDLEPIFGWCPQVDVLCNTAGVLDAYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(20569..20805)
                     /locus_tag="VYO88_000372"
     CDS             complement(20569..20805)
                     /locus_tag="VYO88_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1718538.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(20905..21831)
                     /locus_tag="VYO88_000373"
     CDS             complement(20905..21831)
                     /locus_tag="VYO88_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV1718539.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVDELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(21906..22721)
                     /locus_tag="VYO88_000374"
     CDS             complement(21906..22721)
                     /locus_tag="VYO88_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718540.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(22725..23045)
                     /locus_tag="VYO88_000375"
     CDS             complement(22725..23045)
                     /locus_tag="VYO88_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1718541.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(23252..23332)
                     /locus_tag="VYO88_000376"
                     /pseudo
     CDS             complement(23252..23332)
                     /locus_tag="VYO88_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(23376..25373)
                     /gene="metG"
                     /locus_tag="VYO88_000377"
     CDS             complement(23376..25373)
                     /gene="metG"
                     /locus_tag="VYO88_000377"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1718542.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(25497..26756)
                     /locus_tag="VYO88_000378"
     CDS             complement(25497..26756)
                     /locus_tag="VYO88_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1718543.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESL
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(26758..27459)
                     /locus_tag="VYO88_000379"
     CDS             complement(26758..27459)
                     /locus_tag="VYO88_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718544.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(27443..28642)
                     /locus_tag="VYO88_000380"
     CDS             complement(27443..28642)
                     /locus_tag="VYO88_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1718545.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KTDEATN"
     gene            28928..30274
                     /gene="gor"
                     /locus_tag="VYO88_000381"
     CDS             28928..30274
                     /gene="gor"
                     /locus_tag="VYO88_000381"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1718546.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            30471..31007
                     /locus_tag="VYO88_000382"
     CDS             30471..31007
                     /locus_tag="VYO88_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1718547.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            31058..31144
                     /locus_tag="VYO88_000383"
                     /pseudo
     CDS             31058..31144
                     /locus_tag="VYO88_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(31213..31428)
                     /locus_tag="VYO88_000384"
     CDS             complement(31213..31428)
                     /locus_tag="VYO88_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1718548.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            31526..31846
                     /locus_tag="VYO88_000385"
     CDS             31526..31846
                     /locus_tag="VYO88_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718549.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(31877..32215)
                     /locus_tag="VYO88_000386"
     CDS             complement(31877..32215)
                     /locus_tag="VYO88_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718550.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(32227..32946)
                     /gene="trmD"
                     /locus_tag="VYO88_000387"
     CDS             complement(32227..32946)
                     /gene="trmD"
                     /locus_tag="VYO88_000387"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1718551.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(32936..33454)
                     /gene="rimM"
                     /locus_tag="VYO88_000388"
     CDS             complement(32936..33454)
                     /gene="rimM"
                     /locus_tag="VYO88_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1718552.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(33485..34273)
                     /locus_tag="VYO88_000389"
     CDS             complement(33485..34273)
                     /locus_tag="VYO88_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1718553.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELLE"
     gene            complement(34850..35089)
                     /locus_tag="VYO88_000390"
     CDS             complement(34850..35089)
                     /locus_tag="VYO88_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1718554.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(35109..35381)
                     /gene="rpsP"
                     /locus_tag="VYO88_000391"
     CDS             complement(35109..35381)
                     /gene="rpsP"
                     /locus_tag="VYO88_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1718555.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            35551..35748
                     /locus_tag="VYO88_000392"
     CDS             35551..35748
                     /locus_tag="VYO88_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718556.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKRNMDLLADD
                     SLAGDIILLWRIQFGTFTTET"
     gene            36227..36448
                     /locus_tag="VYO88_000393"
     CDS             36227..36448
                     /locus_tag="VYO88_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718557.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            36531..37334
                     /locus_tag="VYO88_000394"
     CDS             36531..37334
                     /locus_tag="VYO88_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1718558.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(37390..38931)
                     /locus_tag="VYO88_000395"
     CDS             complement(37390..38931)
                     /locus_tag="VYO88_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1718559.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(38933..39415)
                     /locus_tag="VYO88_000396"
     CDS             complement(38933..39415)
                     /locus_tag="VYO88_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1718560.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVRVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(39415..40500)
                     /gene="rlmN"
                     /locus_tag="VYO88_000397"
     CDS             complement(39415..40500)
                     /gene="rlmN"
                     /locus_tag="VYO88_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV1718561.1"
                     /translation="MKPSIHSLPHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITISTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(40521..41051)
                     /locus_tag="VYO88_000398"
     CDS             complement(40521..41051)
                     /locus_tag="VYO88_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1718562.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(41208..41813)
                     /locus_tag="VYO88_000399"
     CDS             complement(41208..41813)
                     /locus_tag="VYO88_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1718563.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(41986..43023)
                     /locus_tag="VYO88_000400"
     CDS             complement(41986..43023)
                     /locus_tag="VYO88_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1718564.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKVDSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(43057..43992)
                     /locus_tag="VYO88_000401"
     CDS             complement(43057..43992)
                     /locus_tag="VYO88_000401"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1718565.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(44545..45735)
                     /locus_tag="VYO88_000402"
     CDS             complement(44545..45735)
                     /locus_tag="VYO88_000402"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1718566.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(45950..47293)
                     /locus_tag="VYO88_000403"
     CDS             complement(45950..47293)
                     /locus_tag="VYO88_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1718567.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(47433..48248)
                     /locus_tag="VYO88_000404"
     CDS             complement(47433..48248)
                     /locus_tag="VYO88_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1718568.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(48300..50480)
                     /locus_tag="VYO88_000405"
     CDS             complement(48300..50480)
                     /locus_tag="VYO88_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1718569.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(50766..51692)
                     /locus_tag="VYO88_000406"
     CDS             complement(50766..51692)
                     /locus_tag="VYO88_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1718570.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(51685..52377)
                     /gene="ftsE"
                     /locus_tag="VYO88_000407"
     CDS             complement(51685..52377)
                     /gene="ftsE"
                     /locus_tag="VYO88_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1718571.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(52395..53490)
                     /gene="prfB"
                     /locus_tag="VYO88_000408"
     CDS             complement(join(52395..53417,53419..53490))
                     /gene="prfB"
                     /locus_tag="VYO88_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1718572.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(53598..54254)
                     /locus_tag="VYO88_000409"
     CDS             complement(53598..54254)
                     /locus_tag="VYO88_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1718573.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(54613..55323)
                     /locus_tag="VYO88_000410"
     CDS             complement(54613..55323)
                     /locus_tag="VYO88_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718574.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(55323..56087)
                     /locus_tag="VYO88_000411"
     CDS             complement(55323..56087)
                     /locus_tag="VYO88_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718575.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(56087..57043)
                     /locus_tag="VYO88_000412"
     CDS             complement(56087..57043)
                     /locus_tag="VYO88_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1718576.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(57047..57916)
                     /locus_tag="VYO88_000413"
     CDS             complement(57047..57916)
                     /locus_tag="VYO88_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1718577.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGAISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFEMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(58184..59344)
                     /locus_tag="VYO88_000414"
     CDS             complement(58184..59344)
                     /locus_tag="VYO88_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1718578.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLVSPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGRDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(59445..59693)
                     /locus_tag="VYO88_000415"
     CDS             complement(59445..59693)
                     /locus_tag="VYO88_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1718579.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(59772..60362)
                     /gene="clpP"
                     /locus_tag="VYO88_000416"
     CDS             complement(59772..60362)
                     /gene="clpP"
                     /locus_tag="VYO88_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1718580.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(60536..61165)
                     /gene="upp"
                     /locus_tag="VYO88_000417"
     CDS             complement(60536..61165)
                     /gene="upp"
                     /locus_tag="VYO88_000417"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1718581.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(61254..61721)
                     /locus_tag="VYO88_000418"
     CDS             complement(61254..61721)
                     /locus_tag="VYO88_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1718582.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLIIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(61740..62297)
                     /locus_tag="VYO88_000419"
     CDS             complement(61740..62297)
                     /locus_tag="VYO88_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1718583.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            62422..63267
                     /locus_tag="VYO88_000420"
     CDS             62422..63267
                     /locus_tag="VYO88_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1718584.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            63326..64501
                     /locus_tag="VYO88_000421"
     CDS             63326..64501
                     /locus_tag="VYO88_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1718585.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDAVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEKNREKS
                     LKNALKTLLPERLAEFFAQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            64521..64988
                     /locus_tag="VYO88_000422"
     CDS             64521..64988
                     /locus_tag="VYO88_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1718586.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLKSSRG"
     gene            complement(65038..65675)
                     /locus_tag="VYO88_000423"
                     /pseudo
     CDS             complement(65038..65675)
                     /locus_tag="VYO88_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        19598 a        14369 c        11937 g        20096 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac aacagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattgacta atactcttcg aaaataaaat tcaaaccaca tcagcgtcgc cttaccatac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttt attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag gcctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataata aaacgcatag
     1021 tagcaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcggag
     1201 gaaaagtatt gtactatgat gattcaacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgataca aggaatcgat tcactggctt atctcgttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggatactat ataaacgctt tgagaacgga
     1441 aaactgactt ggcccagtac agaaaaggat gtcaaagctc tcgcacctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacccctact tctaaaacat tgttagaaat cgatttgact gtcctgatca atttgtcctg
     1621 ttcttgtttc attttactat agaacgattt gaaggcgttt atgatattta gctgtacgag
     1681 agtcttttaa aagtgttttg atggtttgga tttcttcttt agttgatttt atattactat
     1741 tatataatgc ttttttattt tagtctagta taaatagcga gaaatatcta tcctatcttc
     1801 tagaatgtct tccaaacgag aaaactctcg taaacaaaga ggttttagag gcctatttac
     1861 cgtggactaa agttgtacaa gaaaagtgca aataagaaat ctccagatta ggaactatcc
     1921 gtgagttctc tagtctggag atttttcaat agacttcgtt attggacggt taccaagtta
     1981 ctcaaagtac agatttgaag ctgcagataa gactgacgaa atcactttaa tactaaatga
     2041 aaatcaaaaa gcaaactaag aagctagcct caggctgtac ttgagtacgg taaggcgacg
     2101 ctgacgtgat ttgaagagat tttcgaagag tataaaacac tgttttgagg tggtggataa
     2161 atcggctggg taaaaactca atctcaggag aaaatgaagt aaatctcccc acaactatag
     2221 aaaaagattt gattctgctc ctcacacaat aaaatctttt tcttttatta aaaacgaatc
     2281 gtttcacgtg ttttctcata tgaggtaaca aagcgattgg ttacaccagg ctctgccact
     2341 tccaatgctt gagaaatctt gtcaaatgaa gcgtgataat caaattcttt ttcaaaaata
     2401 tctaaagctt cgttaaatgc ttcttgaatg cgttcatcaa atgagcgata gcggttagaa
     2461 tattgcaaga gttgctctgt caaagttgca tattgtacaa tattataagt ttccgtttct
     2521 aaagcttcca tatcattcgt tgcaatttca agaactcggg taacagattc aatgttaatc
     2581 attttttgtt ctaactcaac cattaaatcc tcggtattat tgcttgccgt aaagaataac
     2641 ttcaagaaag tttgtggaat acctggcaga ttgcgttttt ccatgtatcg cttgatagta
     2701 tggagacgat tgacataaac attggccttt tgacgtgcat taatatcatc tttctcaatt
     2761 tgtgtcaggc gctcactaac tgaaatttgc tcatcttcaa tatcttttag ttgagtttgt
     2821 aaatcctcaa gattttcttc aagaactgaa taagcttggg ttggttcttc ttgatttgaa
     2881 gttacctcaa caatagctgc ctcaaaactc tctaattctg tctgaatacg acgaacatgg
     2941 cttgcagctg tctcaggaag taaataggtc ttgttcaaac gtgcaatatc ttctcccaat
     3001 aaagtattat tctctttcat atgttgaagg taagttggaa gagttgcaag tagattttcc
     3061 actactttct gagcagcaat ttctcgagta aaaatatcat acaaggcatt gatttcctct
     3121 tgtgcctgtc cattctcata ttcggcatta tccaattcca actgacgaat attctcttgg
     3181 tttttcttga atgcttcata aagcaagtgg aaacgcgctt caatatccgt ttcaacaaaa
     3241 tgataattag catcaattag tttacgataa ccggattcca aatcctgtaa ttgatctggc
     3301 aattctgtag aaagcgtcgt aaccaaggct ggaacacgat ccacaatatg acttaaggcc
     3361 aaaatgtgat tttctgtatt atccaaaatc actgcggctt ccacagggtc acccgatgaa
     3421 ttcaaggtta caaattgtga aaattcagat tggatatttt ctaattgttt ttcaatttca
     3481 tccaaggctt gaccatactg ttctgaattt tcagcaactc tatgctgaag ttcctcaaat
     3541 aaatccaaag catgaagaac acgaccacta tttttagatt cttgcttctc taagtctgcc
     3601 aaagcattgc gaattgccgc aatatcttct tcaatcaaag taatttgact ctcaatttgg
     3661 tcaatttgat gactggcctt gagaaaacga aatgaatggt tataaccttc tgcttcaaag
     3721 agattatttt caatatcggc aaaagagttg agagataaat cgacccattt ttgattccat
     3781 tcacggaaag ccacttgact ttgtccaatc aagtgcatat tttttacagc ttctacttca
     3841 tcatttactg gaagattgta tagttcttct tttctttctt ctagcgcctc taatctcccc
     3901 tcgtttcgct tacgtagaaa gattgccact acataagcca gaactaaaat gactgcaatt
     3961 gcaaccatta aataaattag ttgtccatta gacatatcaa actccttttt tacttgaaac
     4021 aatcgtaacg attatatcat attttttaga ccaagggaac tacttctccc tattttttag
     4081 acatcaagtg tactatagac agcattttct tcgataaact cacgacgagg ctctactcga
     4141 tcccccatca acatatcaaa gattttatct gcttctgcag catcatctac agaaactcta
     4201 gccatcaagc gatgttcggg atccatggtt gtttcccaca gctgatgatc gtccatttca
     4261 cctagcccct tataacgctg aatagtcggt ttggtacgac cttcactata acgggctaaa
     4321 gcttcttgga gtttgatttc ttgatctgca cccggctgga tatattcttt aatctcgctc
     4381 ccaaccttga caccatagat tggtggttgg gcaatataaa cataaccagc ttctaggatt
     4441 ggtttcatat aacgataaat caaggttaaa agaagggtac gaatatgggc tccatcgaca
     4501 tcggcatcgg tcatcaaaac gagtttttgg taacgggctt tcgaaacatc aaattctgcg
     4561 ccaaatcctg ttcccatggc tgtgaaaaga ctacgaattt cttcgttagc tagaatctta
     4621 tccatacttg ctttttcaac gttcaaaatc ttaccgcgaa ttggaaggat agcctgaaac
     4681 tcacggttac gaccagattt ggctgatcca ccagctgagt ctccttcgac gatgaagagt
     4741 tctgtttcag cagggttatt agaagaacag tctgctagtt tccctggaag gttggaaatt
     4801 tccaaaccag attttttacg tgtgacttca cgcgcacgct tggcagccac acgagccttg
     4861 gcagctaaaa tccctttttc cacgatacgt ttggcaatct gtggattttc catgaggaaa
     4921 tcggagaagg cttcactgaa gaggcgattg gtaatcttga ccacttcgct atttcccaat
     4981 ttggtcttgg tttgtccttc aaactgtgga tttgggtgtt taactgagat aactgcagtt
     5041 aatccttcgc gaacatcttc ccctgttaaa ttatcttcat tgtctttcag taacttattc
     5101 ttacgagcat aatcattgat aacacgagtc agtgccgtac ggaaaccttg ttcatgcgtt
     5161 ccaccttcat gggtatgaat attattggcg aaactcatga cattttcatg gtaacctgtt
     5221 gtgtactgca tggctacctc aactgtaata tcatccatct caccgtctgt atagattggt
     5281 gtatcaaaga ttacatcctt gttctcgttg atatattcaa cgtaactagc aatcccacct
     5341 tcataatgat aatgcttggt ttgttccaaa ccttggcgct tatcagtgat agaaatttga
     5401 agaccgcgat ttagaaaggc caactcttga atccgtttat ttaatttatc aaaatcaaag
     5461 gttgttgttt cagtaaagat ttttgggtcc ggtataaagt gaaccgttgt tccagttcta
     5521 tctgtatccc caaccacctc aaggtctgca acaacatgac cacgacggta ttcttggtaa
     5581 tgaatcttac cgtttttatg gacatgaacg tctaattgag tggaaagggc attaactact
     5641 gacgacccca ccccgtgaag accacctgaa accttgtatc caccaccgcc gaactttcct
     5701 ccagcatgaa ggactgtaaa gacggtctca acagcaggac ggcctgtttt ttcctgaata
     5761 tcgactggga taccacgccc atcatccaca acagtaatcg aatcatctgg ctcaataaaa
     5821 acttgaatat ggctggcaaa tcctgccaag gcctcgtcaa ttgagttatc aacaatttcc
     5881 cagactagat ggtgaagacc ttcttttgag gttgatccaa tgtacatccc tggacgcata
     5941 cgaacagcct ctaagccctc taaaacttga atttgactgg catcataatc ctgtgcctgc
     6001 agatttttga tttcttctgt catcttattc ctttttctta tatgtctaat acttgtctta
     6061 aattcacgat actggtaaac aagtgggtat caagtcctgc agcttgacct gcttcgatat
     6121 caatcggccg atcaccaatg acaagaccag agctaatctg atacttttct cttaaataaa
     6181 gcatggattc gggatttggc tttctcttaa agcctgagct agaagtcacc acttctgtaa
     6241 aataagctgc tatagaggtt ttttctaaaa tttccaaaac ctgatcattt cgatgagaga
     6301 ccaaaaaatg acggccacct tgatttaaaa tgtcttccaa taggtcagaa actccttcaa
     6361 ataaaatcgg gtgttcaagc tctctggctt cattttcctt gtacttttct aaaaaattct
     6421 ctaaattggg agcgaatgtc tcaatcgcaa aaggagtaga aacctttaaa gtttgataga
     6481 cactgtcatg gtcttgtgtg ataccataca gtgccaatgt ttcaacaaat gcagctgttg
     6541 aagtttcata attatccagt aaagttccac ctaaatccca gatgtaatcg tgatatttca
     6601 tacccttcat tatagcattt ttttatgaaa aaagcgatga tttccctgag ttttccacat
     6661 aaaaaacgag agaataaccc ccgttttact gatttttacc aaagacatct cgatagagca
     6721 ttcctgttcg taaactctct gcgtcccctc ctagttgctc caccaactcg taggcaaagg
     6781 caagggctgt tgaaggaccc cgactggttg tcaactgacc atctaccact actgtttcct
     6841 tgacgtagtg accatcaagg atttgctctt gaacgtcgtc ataacaagtg tatcgcttat
     6901 ttttcaatat ctctgcttga ttgagggcaa ttggtgccgc acaaatggct gctagtttct
     6961 tcccttcttg ctcgaagctt tgcaattctt gaatcaaggt ctgattatca cgtaaatgtg
     7021 cagaaccagg catacctcca ggaagaacaa tcatatcata gtctgataaa tctccatcaa
     7081 agacatgatc tgctcttact tggattgcat gcgaacccgt tacttgctct tcaaaaccaa
     7141 ccatatcaca tgtgatattg gctcgacgca agacatctac aactgtcaag gcttcaattt
     7201 cttcaaagcc ctgagctaac ataactgcta cttttaccat gattttctcc ttatttaatt
     7261 tgttttaata caaccttttt ccgtttgaat gggacttttc cgctcttttc ttcagctaga
     7321 ttagtctggt aactcatcga taaaagcaaa ccaacaccaa tcagattact gataatagct
     7381 gatccccctt gcgaaatgaa aggcaaggga atccccgtca aaggaagtag tccagtcaca
     7441 gcaccgatat tctcaaagat gtggaagagc aacatcataa tcaaacctgt ggaaatataa
     7501 gtgtagaact ggttatttga tttaagagta atcttcaaca tacggtaaat caacatgaga
     7561 tagagggcaa taaccaggac agagccaata aagccaaaat cttctgcaat aaccgtaaaa
     7621 atcatatctg actctcgaac tgggataagc agattcgaag cattaaatcc ctgaccaaat
     7681 aagccaccac tcccaatggc aatctgccct tgagcctgct ggtaagtcgt tgtttgggca
     7741 aactcaaagg gattgagcca agccaaaatc cgattaattt ggtaggtcgg cattccaatc
     7801 tggtgaagaa aagctcgtcc gtccttgcta ataaaaatag ctaagaaacc agcaactcct
     7861 gttacagcag tcacaaatac tgggataata attttccaag aaacccctga taataaaacg
     7921 attcctgaga aaatggctac aaaaaccaaa gccgtcccca agtcactttg aagtgctaaa
     7981 agaactagga ctggaatggt aaagagaatc atccagaaaa ttaacaaaaa gtccagcgga
     8041 accgtgcgtc tccattcctt atgtttcttt gtaaattgga caatgacacg agccaacatg
     8101 aggatatagg atatcttcat aaattctgac ggttgaaata gggtaattcc atttattgat
     8161 acccagtttt tggcacccgt tgatgcaact aagcttggat tataaaatac aatcggcaag
     8221 atcataagtc ccaagcctaa aatatataga aagggggtca ccttccaaag aaattctgta
     8281 ttaaagagca tgaccacaaa accaatcaca agccccaagg caatccaggc gacctgctgc
     8341 cctaaaatgg gcagaatatt attgggataa tcatgactaa cggctatata gatagccacc
     8401 acaccgatga ccagtagaaa aaatactggc aagagcaaac tgtaatcgac tcttgagtcg
     8461 agagaacgtt tcatatatac taaccttata ctttcataca atactattta tcaaagttca
     8521 ttaaaaaatc tatcaatagc ctcgtcaact tcggatcgag agatggtttt aacagtcgct
     8581 tcttctgcta gagatgctac tatttgtttg ccgtatcgtt ttccgacgat tctcctatcc
     8641 aaaataagag ttaaggaacg ttggtattca cgtctcatac ttcttcccaa agcctgtttt
     8701 aaacgaataa tggccattgg caattgataa tcataaaagg catttttccc ttcttgattc
     8761 agttcttgat taatcttttt cgtcaagggt tcttgaggat tttggaaagg aagcctcggt
     8821 acaacttgaa tcacaaaagg atggcttgaa aaatcaactc cctcccagaa acttgctgca
     8881 ccaagcaaga tttgttgttc acctttttca aagcgtttct ttagctgatg aacatcccca
     8941 tttttatact gggccaagtg gctaactgta agtaaatccg atactgctag aagcatgtct
     9001 ttagcggtaa agagaaccaa aatcggttgc tggaaagctt gaatttccac tagtaaagca
     9061 gctacctctc tggcatagac ttctaaggag gtttctgtta ccagagggaa atctttgacc
     9121 atgaccactt cttgttcctg ttttccccga gattcaatct tgacaaattt ggcttcagga
     9181 tagcctaaaa ggtctgccaa agaaaccctc tgactaatct caagagtagc tgatactccc
     9241 aagacttggc aactctcagg aagtaaagag gacagaagag tacggcctga ttttgtagaa
     9301 gaaatctgaa ttttcttttg actcgtttca gttacttcaa gccagtaatc accttcagct
     9361 gtaaaatagc gaaccagctc atcaaagcct tccacttcta attctgaaaa atactgatgg
     9421 agattgtcca gagaatctaa gatatttttc ctagatttgc cagactgaaa ttgttctatc
     9481 aagtagagac actcaaagcg aatactttct agtatccgtt gttgaaccct gttttcttct
     9541 cctactaaag ccttatcaat taaatcgata atagattgta tatcgtaggt ctcttgaagc
     9601 agattttcta gagctaacaa aatcttttgg acttcatcaa taatcagtaa acggtcactg
     9661 acaaattcag gattatcttc aagtctggtc acgagatagg catgattagt cactaaaagc
     9721 ttgcaagtct ctgccctttc ttgactacgt ttccaaaaat cttccgtcac aaataagctc
     9781 tgggatgata aattcccatc atgacgaagg tctgctagaa aatgttggta acggtagagt
     9841 tgcccgattt catccaaatc tcctgtctct gtctcagtaa gccagaccaa gacttgcatt
     9901 ttaaagcgtc taaataagcg attttcatca ttttcctgca aggaatgata aaaggcatcc
     9961 aacttcagat aattttgtgg tccctttaag ctatgaatat ctgtatggaa cacttccttg
    10021 agacgtttac cttcttcttc catgatttga ttttgaagaa tctttgtcgg aacactaaga
    10081 acaatttgtc gctctttgga ttgagataaa gcgggtaaga gatagccata ggttttccca
    10141 atccctgtcg gcgcttgaat cagagagaca ggttcatctt tcaatagcaa gccaacctct
    10201 ttagcaaaac tttcttgttc ctccctcact tcaaggttca acagagaaat atttttagaa
    10261 aagtcttgag atagttttcg tggctccaga gaagctgccg ttttcttaaa atacagacct
    10321 tgaacttgga ccaagtctgg agaactcagg atagattggt tgcgataagt ttcctcaata
    10381 accaggtagg actcatatag gagagcgtca gccatttcca gcaagcgttc caaaagacct
    10441 ttaggaagct gggtcatctt ttcccgtaaa aaaagaagta attctgctgt agcttgggca
    10501 tctgaaaggg ctgtgtgtgc gtgtttaaga ggaattccta attctcgaca caaaatcggc
    10561 aagctatatt tttccagttc agggaaaaag acctgggcca attcgaccgt atcaacacga
    10621 gggtttctta gctcatagcc ttcaaaaaat aaattttccg ccaagagatt agcatcaaac
    10681 tgaacattat gggctacaaa aatcccatcc tccaccaagt caaatatttt tctggcaact
    10741 tgcgaaaaat caggtgcttg cgccagacgt tggtctgtca atcctgtcag ttctttgata
    10801 tgagcatcca agggttcatg tggattgaca tccgtcgtat agtgatcgac gatttctccg
    10861 tcctcaatca cgacaattcc cacttggata attttagcct tactacctgt gctagttgcc
    10921 tctaaatcca ccacaacata gcgattacca atcgttttca ttataaaaaa ttataccaaa
    10981 aaaagggcca tttggcacct gcaaacatag gataattttc aaactcaaga acactacttt
    11041 tcttaaaaat cccatcgaat agagcattct agcctgctga ttttttaaaa tagtgaagaa
    11101 atacgaaaaa ttgagagaag aaatgttttc atcttccttc tctcaacgaa tcatgtattt
    11161 tatttaacca tgtcaggatc gtagtcataa aatcctgtat caaggaaacg gtttttaggg
    11221 tgaagtttac gaacttcttc atccagcaag aaggcttggt catggctaaa gttgccctct
    11281 tgaatcaagc tacgcgcttg gataaagagt tttgcaatct caacaaagtt ctgaccagga
    11341 gtgtagagcc cttctagttt ccagcgagta aagccatgct ccaccaattc tgttaatttg
    11401 atcatcaaat caaggtcatt gttggcaaag atatgggtcc catgattatc ttcaaaaatg
    11461 gaatagtggc tctctggatc acttggctca gccaagaaga ggtcacgttt atgcgtcttt
    11521 tcatcatcga tatgtgtaaa gttatagtag ttttgcaaga gtggacgttt agaatgatgg
    11581 atgacgctag caccgtaaac caaaacttca gcaggaattt ccaaaatctc tggcattttg
    11641 aaaagttcag ctgatggaat ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt
    11701 ccccagaagt taatctgacg actgctagtt accatggttg aagcatcgta gatggtctta
    11761 aatgaataac catcgcggtt aactacgtaa aagacgcctg catccccaat cgtaatatag
    11821 tctgtcttga tttcttccaa gaagtctaag aaaggcttga tacggtccat catatcttgg
    11881 tgcatgagag cattgaccgc aacgatcaat tccttaccag catcatgaac caacttagcg
    11941 atttcacgta attggtcata actaaaggtc gttggcagac gaaggccaaa atctttctca
    12001 ccgacataga tacggtctac gccagcttcg agtagttgtt caacttgttc aatactttca
    12061 gcagttgctg taatgacaat cttttccata agaaaaatta taccacattt ctccaaaatc
    12121 agccatgctt tgaaaatgaa aagggacttt attctttttg taacctttct gtaataattc
    12181 tctaccgaaa aaatgataaa ataggtatgt actgttaagg agagaatcat gcccgtaaga
    12241 aaattacaat cctatgaggt agactatcaa gaagaattaa accagcagct tcctcattac
    12301 caagcttata cacctgaagc gcaatctgat gccaatctca aggaaatcct attttttatt
    12361 aatatcgctg ttttttgtat ctgtattgct atctttagtt ttatcttttt agcattaaaa
    12421 ttatcaactg ctcttgcctt tgccgcagca atcggattca gcttacttgt tttaaaagtt
    12481 caacggtcta ttatcaaacg aaaacgtaga agataaatcc aaaatatcgc cccaattgga
    12541 gcgatatttt tattttttct ttttagatgg tgtctgaatg gcaatcttca cttcaaagat
    12601 tgttcccttg ggtttattat ctttgacagt aacagttcct tttagagcat ctacaatttg
    12661 cttggctagg gataatccta aaccaaaacc acctttttgc cgggttctag ccttgtctac
    12721 tcgataaaaa cggtcaaaaa ttttcttttt atcttctgtc gaaataccga ttccattatc
    12781 agaaacaagt aaataaagat tgcgatcggt cgccgagata agaaaatcaa tttcaccatc
    12841 ctcctcagta tacttgacgg cattatcgaa aagaatggtc atcagttgtt tcagaagaag
    12901 ctgatctgtg acaattgttc gatggatacg attttcaaaa cggaagacac gattattttc
    12961 cgaagcaatc atctcgtagt ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc
    13021 aagctccggc ttaatcccat catctctccg agctaagttc agcaagcttg tcgttaaaaa
    13081 acgcatattt cggacttctt ccaaactcga tgcaatgctt tcgctcacat ccataatggt
    13141 agcttctggc ttacgaaaaa gggtctctaa gcgattttgc aaaactgcga gtggagttcg
    13201 taactcatga ctggcatttt ccacaaaaga ctgttgcttc tgcatactct caagcagggg
    13261 cctaacactg accctagcta gatagagact ggcaagtaaa gacaaaatcc agaaactagc
    13321 catcacgacc acaatcaatt gctcatgctt ttgactagcc tgctccaact gactggtatt
    13381 aatcaagaca gcagcatact ttatattggt tgaaaccgaa ctaatattgg tctccatcaa
    13441 aatcacacga tagatttctt cctgcccata gctattaaaa acctgaatct ggtagatatg
    13501 tcctagttct ttcttttcta acttaatctt atccaagccc aaaaatcgat ttccagaaag
    13561 aagttgagta aagtctttat caaagagaat gacttccgta ttggaactga cattaggttt
    13621 tatttctact ttactagcgt ccgccctagc attttctaaa tctttaatct cttctgttgc
    13681 cctatttata gccagctgaa taactgcttg aggattttca ctcagtccat gaagcttatc
    13741 gtccaccgaa gtataaagac tcgaatgcat gacttgtaaa ataatcagag tcattgtaga
    13801 aaaaatcagg gtgaagacac cgaagttgcg gataaaataa ctaaagtcat ccgcatacca
    13861 tgttttttta agtttactga acatctttta aaagataccc aacactacgc aaggtttgca
    13921 aattctctgc aaaagtggtt ccctttaatt tcttacggac ttttgaaaca tagacttcga
    13981 caaccgaaat cgttgtatca ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag
    14041 gcaaaatcac attttgattt tgaaggaaat aaactagtaa atcgaactct ttccccagca
    14101 attcgacagg agtatcttca actttaacgg tattggttga taaattaacc acgatattcc
    14161 cataagtcaa ggtgttttca ttaaacttcc ctgaacgttt gagaagggcc tgaatccgca
    14221 ttttaagttc ttctaggtag aaaggtttgg tcagataatc atccgctccc agttcaaatc
    14281 catgtccctt gtcatccaaa ctttccttgg cagtcataat cagaactggt gtcgtaattc
    14341 ccttttcacg caattctttt aagacttgga aaccattttt ttctggcaac atcaaatcca
    14401 gcaaaatcaa gtcatagaca ccactctcag cttcgtagag accttcttct ccatcaaata
    14461 cctgcataac atccgcaaaa tcgtctaaaa agtcaaatac tgaatttgac agacctaggt
    14521 catcctcaac caataagatt tttatcatga gaaactcctc cttattaaaa ctattatacc
    14581 aaatttgcct taaaaaaaac tcaactctct gcattttaca tgagatagct gagttttctt
    14641 tttattttag gcttatttat gcatttccgt attgaagaac aactgcttcg actgcagctt
    14701 tttcacggct aatcaagtca acacgtgctg caatttcctt gattcccata ccgatgttac
    14761 ggctaagagc aaggtcagaa agttgcggct caaagaactc cttgtattcc gccaagcgtt
    14821 gctgagtctt aaatacatga gcaggaagga taacaaagct atcaaagctc atatctcctc
    14881 caagggctgc cttaatccaa gcccagtttt cacgcgccca agaccaagct gttttctgag
    14941 ttgcttgatg agctaggaat tggtaatacc aagcagacaa gtcctgtggt ttgaccacaa
    15001 atttgtcctt ccaagaagta atcaagtttt ggatattatc cgcatctgta ctgtatgcaa
    15061 gagctgctgc caactggcgt ttaaagacag catctgttgc gtgagtataa gtatcaagat
    15121 aaagtgctaa caagtcttta gtctcatgat gtttcatctc attaatcaga acttgtgaac
    15181 gaatagctgc tgggagttct gcaagattct ccttgtgtgt tgcgaagatt tggctagcga
    15241 cttgacgagc ttctgcatca tttgagcgaa tcatcatcga aacagccagc tgacgaacca
    15301 attcatcctc atctgattct ccgtctttag cttcaaaacc aagacggtca tagttatgac
    15361 gagccaattt agcaaccagt cctttgaagg ctgtttcagc atccgttcct tcatcaataa
    15421 agcgctcaag ggctgaaatc acttgagaaa cagctgaaac caccagataa gactcttcct
    15481 tagcaagttt atcaagaact ggaagcaagt ctgcataaga aatgtgccct gcctcagcca
    15541 acaaacgacg ttcttgaaca atttgcagtt tgcttgtgtt atcaagtgtc tctagctcag
    15601 caagaacagt ttctaacaag tctccttgat agtcggtaat atagtgggca gtattttcag
    15661 tgttgagacg aagagctcct tcattttcag caagaagagc tgcgtagcca gggatttcga
    15721 tactttcagt ttcgagtgta tcaggcaagc ctttccagtt gctattgagg ggcaccaccc
    15781 agagacggtt cttgtcttcg ttctcaccga tgaagaattg tttttgtgaa atcttcaaga
    15841 catcattttc aactttgaca gtaagaactg ggtaaccagg ctgttccaac caagaatcca
    15901 tgaaggctgc gacatcacgt cctgacgctt gaccaagggc atcccaaagg tcactaccaa
    15961 tggtgttgct gtattggtgt ttttcaaagt aggcatgcaa acctttagca aaatcagcat
    16021 ctcctagcca acggcgaagc atgtgcatga gacggcttcc tttggcatag acgatagcgc
    16081 cgtcaaagag tgtattgatt tcatctggat gtttaacttc gacgtggaca gactgaacgc
    16141 catcagtagc gtcacgttca agagcaagag gtactccacc tgtttggaaa tcttcaaaga
    16201 tattccagct tggttcgatg gtatccacac agacgtattc catcatatta gcgaaacttt
    16261 cattgagcca aaggtcatcc caccatttca tagtcacgag gttcccaaac cattggtgag
    16321 ccaattcatg ggccacaaca agggcaactt gttgacggct agcaaatgta gagttctcat
    16381 cgacaaccaa gtaaacttca cggtaggtca caagacccca gttttccata gcaccagctg
    16441 agaagtcagg aagggcgatg tggagagatt gaggaattgg atacttaact ccatagtaat
    16501 cttcgtaaaa ctcgatagag cgaacagcga tatccagtga gaaatcaaga tttgaaagtg
    16561 gatgtgcttt ggttgagtag acacctacca gggtaccatt tttagtttta gcggtcaccc
    16621 cttgcaaatc accagcaaca aaggccaaca agtaagaaga catgcgaggt gttgtctcaa
    16681 acttccagat acctgtttcc ttacggtttt caacagcgat ttctggcatg tttgacaagg
    16741 ccaattcacc ttctgcttgg tcaaagcgaa gagagaggtc aaaagttgct ttggcttcag
    16801 gctcatccac acatgggaaa gcttcgcgcg caaaatggct ctcgaactga gtagacaaga
    16861 cctccttctt gactccatca actgtataat aagaagggta aatccctgtc atgttgtctg
    16921 taattttacc agaaaaggca agaaccaatt caacttgacc agcctcagcc aattcgatat
    16981 gaagggcttc attgtcatgg tcaactgtaa atggacgagc ttgacctgca acttctacag
    17041 aggtgatttc caagtctttt tggtggaggg agatgcggtc actctgtgct tgaccagtga
    17101 tggtcacttt cccagaaaaa gtcttggtct cacgactcaa atctaaaaat aaatcataat
    17161 gttcaggaac aaattgctta ataaaatgtt caactgcttg catagttttc tcctattcta
    17221 agtttaagag ctgctgctct tcttcaaaca aacttattat atcatatttt gcttgaaaaa
    17281 aaaggattgg acagcgattt ccaaaacttt cttccttcta atagtctaca gtgggtagac
    17341 cttgcgaaat tcttctaaaa caaccttgct ttcagatgta aaagtcagcc ctacttcacc
    17401 caaacagtct gtgaaaaagt cctcatgaac ctggcgccaa taggcaagtg atttgtctcc
    17461 ctcaccttcc ttaaaggcat gttgcgcaga aacttgattg aagagttcaa cagaaacctt
    17521 tgtaatttcg acaatgcaga cagcctgatt ttgactatct aaaatgatat cgaaggtccc
    17581 tacttgggga agtggttcgt cttctagtac atagaggtca taggctgatg ctgttgctgt
    17641 cttttctcct ttaaacacca aatccgctaa aagatctggt tcaactccaa aagcccaagc
    17701 atcgatttca tctccgatca aaggattgat ttgcttgtat ttattccaca tttcttgcgg
    17761 tatcatgggt actcctttgt aattttttac tttcttcttt tatgtgttta agatgatctg
    17821 gatggtcaat ctctaaatca aaaatctctg gaatagaact gtagtggata atgcacttga
    17881 tacccaactg attcattttt tgtatgaaag aagtattcag atagcctgct acagcaaaat
    17941 caatcttgtt ctttcttgct ttatcctgca tatctcttag catatctaac attattggac
    18001 tttccatatc atgccattga ctgtttctca tagtcgcaaa aacaaaggaa gtcaaatcat
    18061 tcattccaac tacaatcttt gaaatgcccg tttccagtat actagataag tcaaaatacg
    18121 ctgacggtaa ttcaatcatc gttccgactt tcccagtaaa accctgctga cgcaatactg
    18181 taatagcttg ttttaattgg tcgtcatcat tgacaaaagg aaagataaca gatagattgg
    18241 ggttggtttg ataaacttct gtaacgacat gtgcttcagc ctgaaattca tccaaacacg
    18301 ccagtaaacg cctggttcct ctatagccaa acaagggatg cccttcgtca aaaaactctc
    18361 tagtccccac taaacaattg gcttctgtat tcgttaattc agaaaaacga taccaaactt
    18421 cttcatctga gtacagggag cagatagtct ctagataatc ttttacaaat tgctgacaac
    18481 ttgctaatat gatgttttga ttaagctctc tcaacaaata ttccccacga atcatgccga
    18541 cgtggtgaaa tagttgagga taaatttttt caagaatttt ttcgccacta agggcaagtt
    18601 gatttctcat agccattcac ctcgtcttaa aagatacaat atcatatata attatatcaa
    18661 aatttcctct agttcaaaag cttcataagg ttcagataac tcatatccta aaaattctgc
    18721 tacttttttg gaagcctcat tatgagcatc ccaaagtgga aacatatctc tatttaaact
    18781 ctctagaatc attgcagcac caagcttttt agcaaatcca tttccttgtt cgtttggtct
    18841 agttgcaact tccacttcaa ctgctttacg gtaaactaac cctgaggaaa tcccagcaat
    18901 cagttcatta tttttaagaa tcacaaagcc aaatccacct tttaaaacaa aatcctgata
    18961 ggactcaaaa tccccctgta aatcctgtga ccattcttcc gtagaaaagc agttataaat
    19021 atgattatca ataggcacaa tattgtaacc ttcctctaaa tgagtaacta gattatttaa
    19081 aaattcaact tgaaaatttg ccttatcttt aaaagaatag cgagtaaaag aatttagccc
    19141 cacttttcga tgcagaaaat cttgccaatt agtattttct gaaataataa tcttataatc
    19201 taaaccatat tttctaacaa aatcttccca aaatctggaa tccaactccc ctgctaggta
    19261 tagaaaattc ccaacatcat aaaagcttgt tgtcctatca ttgtttcggt agacagttcc
    19321 aatttgagat ttaagaccat agagaaccat atttttcttc catgttttaa atagttccat
    19381 tatccctcta cttcaccttc caattcatgt aagaagtctt gtccagttct ggaaatccta
    19441 ataattcaga cttaaccttc aagactaatg gcgatgcatt ttcttctgta atctcttgaa
    19501 tatccatcca aatatatcca agtgaatcat tcgcaccatc agacacagct tccgaagtcg
    19561 taacttgagg tgcactctca ttcatttcaa catcatacaa ggccatgaca tggtgaacca
    19621 taaaatttgt taactcttct ctgacgaaaa catcgtagat tcaaggatta gagtagcttc
    19681 taacagtaaa tcccgtctct tccataactt ctctagtcag cgtttccgtc agtccttcac
    19741 caagttgctg actgcctcta ggtagatcat accgatgttg ataagggcct ctcgtttttt
    19801 caatgcagag taacttccca ttttctaagc aaacagcgta gactccaaag tgttttttga
    19861 tttccatcca actcctccta cttcaaagac cagccaccat ctattgtcaa gatttgtcct
    19921 tgcatggcgc tcgcttttcc acttgctaaa aaaagactaa gctctgctat ttcctctggc
    19981 tcaatccagc gcttgattgg ggtttcacta gccacccagt cagccaaacc acctggttca
    20041 aaatccgcag cggtcatagc tgtcttgact gctcctggag cgataccaaa gacctgaatc
    20101 ccagcttcag catagtctag agccaactgc ttggtgaagc cagccaaggc atgcttggat
    20161 gaagtatagg cgtgaccacc tccacctgct aggctagaag caatggaaca catattgatg
    20221 atgattccct ttttattttc cagcatttgt gtcaaataat accgagtcaa ctcaacagga
    20281 gtcatgtagt taatttcaaa aatctcttga atttcctgcg cagtctgttc caacagtggt
    20341 ttgtaagcat ccaaaactcc ggcagtatta cacaaaacat ccacctgagg gcaccagcca
    20401 aaaataggtt ccaagtccaa ggtcaaatct ctctgtaaaa aatggaaatc accctctaag
    20461 agtggatttt caccttggtc aactccataa acttgaaagc ccttctctaa aaagagtcga
    20521 gcctgagcca atccgatacc tgaactcact cctgtaataa gtacacgttt agtcatgcac
    20581 ttctacccaa tccgttgcca aaacatcaca agctgtcggg ctccacatgg aaaaaccttc
    20641 tccttcgcca gaaacgttga ttaggaaata aggtgtcact tcaagtgcaa gcccgttttg
    20701 ttcaatggtg tcaaaaagtt ggacatagtt ttccgcacct ccccaaccag ttcgtacata
    20761 ttttttctta gcctttaagc caggtagaat ttcttcaaat gtcatgtttt tctcctttaa
    20821 tgtcaataat tctccccttc attataacaa aaaaaccgct ttaaaacggc tttttgactg
    20881 tgatttattt acatcttctt ctacttacgg caaattattc cctgcagcaa gataaatttc
    20941 ataccattct tttcttgtta agctaaagtt tgccgctcgg ctaacttctc tcaagtgctt
    21001 aggatttgtt gtacctacga ctgcctgcat ttttgctgga taacgcaata tccaagaaat
    21061 ggcaatagtt gaagaggtta ctccatattt aatagctaaa cgatcaagta cttgatttaa
    21121 agcttgaaat ttctcatttc caacaaagtt ccctttaaaa tacccgaatt gcaagacaga
    21181 ccatgcttga atgaccacat cgtgtaattt gcaatattca aaaatgctgc catctcgcat
    21241 agctgcttga ctatcttcca tattaacatg aaaagctgat tcaaatcctg gagtaaaagc
    21301 cgcactcaat tgtagctgat taacagctaa cggctgcttg acatcttttt taagcaactc
    21361 catcatcata ggattttgat tagaaactcc aaaatctcga actttacctt gtttataaag
    21421 gagattaaag gcttctgcta cttggtcaga ttccatcaaa gcatctggtc gatgaaggag
    21481 caagctatct agatgatcaa tcttcaatct ttgcaaaata ccgtctactg attttataat
    21541 atagtcctta gaaaaatcaa aataggtaaa ttcttcaatg cgaatgccac atttggactg
    21601 aatccacatc ttttctctta aatctggacg attttttagg acaagaccta acagttcttc
    21661 acaacgacca cgaccataaa tatcagccaa gtcgaaggca ttgattccaa cagaaagtgc
    21721 tgtttctaca agctcatcaa cttcttttac agacttatct tttattctca tcattccgag
    21781 aacaatttct gataattctt tgtcatcttg accaagagtt atgtatctca tcaaattttt
    21841 ctcctttaat ttctaacatt cttcccttca ttataacaaa aaaccgcttt gcaacggctt
    21901 tttgactata cttcactcca ttttatcttc ttaaacccac ggaacaagac aaagattcca
    21961 ataaagagga cagctaaagg aataactttt gtaaggaaaa catttgaaat tcccatccac
    22021 tcataataac ggagcagaga acccaccaca agatgggcaa taatcatact gacaaatgga
    22081 cgaaagaccg cttctttcca attccaaata ccgataacta gcgaaatcgt aaagacagac
    22141 aaactatccc agggagccgg aatataaaag gctccttctt gtatgaagct tgccattcct
    22201 acatatccta aaacaactag aagaactata gtcccaacaa caatgtaagt gccaattttc
    22261 attttaggag aatcttggac taaacttctt cgtaaaattg tggccacaag tccaaatcca
    22321 atcagaaaaa taagaagttg ccctaaaaat gtgagcaaat tgactgttaa gagaggacct
    22381 ttagaaaaat cacttagtag ttgataataa cgtaataccg ccaggacaag aattggcgtc
    22441 aaaagagact ctttgataga actgcgaggt gctcccttga gaatctcttt cattattttt
    22501 ttaggattct tacctagata atcctctgca ctcatgccat ctcgttctgc ttctgagaaa
    22561 tctagcatca tcaaatagat ctgctctctg agatagtctt catcatagag aaatccagca
    22621 agattaaaac tttcccacaa ctcctcaaaa tacttttgat tctcctcaga aaactcatgt
    22681 agcaaagcgc ttgtttcttc gtaatacttc attttcttca tggtttaacc cccattctta
    22741 atcccttcta ctttttgact caaatcgtcc cattgttgcc aaaagactga gacacgctct
    22801 tctccttctt tcattaatga aaaatacttc cgatctggac catctggcga cgggcgcatg
    22861 tcgcctctta tccattgatt tttttctaac ttttgcaaca aaggataaat agttcctgga
    22921 acgatagtat caaatccagc ctctcgcaaa gtctgaacca actcataacc ataccgctct
    22981 ttttgaccaa tcatatccaa gacacaacct tcaagaacac cttttaatag ctgagtttct
    23041 ttcatcactt ctcccttcta atctattttg taatacctac tagtaacttc acctatagta
    23101 tatcacttct acactagttt gtaaagcata atagttaata ctcttcgaaa atctcttcaa
    23161 accacgtcag cgtcgcctta ccgtatgtag ggttactgac ttcgtcagtt tcatctacaa
    23221 cctcaaaact gtgttttgag ctgacttcgt cagtttcatc tacaacctca aaaccatgtt
    23281 ttgagcaacc tgcggctagc ttcctagttt gctctttgat tttcattgag tataaataaa
    23341 aaaacagaac tagtctgaac tagtcctgtc tacttttacc caatcacact tccatttggt
    23401 acagctggat caactgtgag aagggttaat ttgccatcat gttcagctga gagaatcata
    23461 ccctggctga catatttttt catcatttta cgtggtttga ggttagcaac gatttgaact
    23521 ttcttgccga ccaattcttg ttcatttgga tagtattttg caattcctga aagaatctga
    23581 cgatcttctc catcaccagc atccaagcgg aattgaagca acttatctga accttctact
    23641 ttagacactt ctttgacttc tgcgacacgg atttcaacct tgtcaaagtc ttcaaacttg
    23701 atttcatcct tgtttagttt gagctcaact tcgtccggat tccattcttt ttcgactgct
    23761 ggtttattgc cttccatttg ttccttgata taggcgattt cttcttccat atttagacgt
    23821 ggaaagatag gtgttccttt ggcaactaca gtcacatctg ctgggaagtc agccaaactc
    23881 aagttttcaa gactagaaac ttcttccaaa ccaagttgag tcaaaactgc acgactagtt
    23941 tccatcataa atggttcaat caagtgagca actacacgaa tgctggctgc caagtggctc
    24001 atgacacttg ccaattggtc acgaagagct tcatccttgg ccaagaccca tggtgcggtc
    24061 tcatcgatgt atttattggt acgagagatc agagtccaga ctgcttcaag cgcacgtgga
    24121 tagtcaactg cttccatgtg tgtatggaag tctgcgattg attgttctgc aacctcagca
    24181 agaacatgat caaattcagt cacaccttct acataggcag ggatttgtcc atcaaagtac
    24241 ttattaatca tggaaaccgt acggttaagg aggttcccaa ggtcattagc caattcatag
    24301 ttgatacgac cgacatagtc ttcaggagta aaggttccgt ctgaaccaac tggaaggtta
    24361 cgcatgaggt agtaacgaag tggatctagt ccataacgct ctaccaacat ttcagggtaa
    24421 acgacattcc cttttgactt agacattttt ccgtctttca tgacaaacca accatgggca
    24481 atcaaacgat caggtaattt aacatccaac atcataagaa ggattggcca gtagatagag
    24541 tggaagcgaa ggatgtcttt tcctaccata tggaagactg ttccattcca gaacttgtca
    24601 aagttaccat gttcgtcttg agcgtagcca agagctgtcg catagttaag aagggcatca
    24661 atccaaacgt agacaacatg ttttggattt gatgggacag gcactcccca tgtaaaggtt
    24721 gtacgagata ccgccaaatc ttccaaacct ggctcgatga agttgcgtag catttcatta
    24781 aggcgaccat ctggcgtgat aaattcagga tgagctttga aaaattcgac caaacggtct
    24841 tggtatttgc taaggcgaag gaagtatgat tcttcagaaa cccattcaac ctcatgacct
    24901 gatggagcaa taccaccagt cacatttcca gcttcatcac ggaaaacttc tgccagctgg
    24961 ctttctgtaa agaattcttc gtctgatact gaataccaac cagagtattc acccaagtag
    25021 atatcatctt gagcaagtaa gcgttcaaag acttgtgcga caactttttc atggtagtca
    25081 tcagttgtac ggataaattt atcgtatgag atatctagta attgccagag ttctttaact
    25141 ccaaccgcca ttccatcaac ataggcttga ggtgtaatac cagcttcttc cgctttctgc
    25201 tggattttct gaccatgttc atcaagacct gtcagataaa atacatcgta gcccatcagg
    25261 cgtttgtaac gtgctaggac atcacatgcg atagttgtgt aggcagaacc gatatgaagt
    25321 ttcccagatg gatagtaaat cggcgttgta atataaaaat ttttttcaga cataattttt
    25381 cctttccagg caaatgaaac ctgtttttct aacacttcat tatatcacat ttttaatgaa
    25441 tttcaatagg gaaatccata caaaaacaag atagacgagt gtccatcttg ttgatctcat
    25501 tcataacgaa gggcttcaat tggatcaagt ttcgatgcct tgttggctgg caagactcca
    25561 aaaatcatac caacactagc cgaaactgca agactaaata gggcgactgg gattgatact
    25621 ccaacttcta taccttctat taaaccttgc agtaacaaac ctgctaaggc agttaaacca
    25681 cttgcaattg tcaagccaat taagccacct aacaaggtca aaatcatgga ttcaatcaaa
    25741 aactgaatta aaatattggc acgtgttgca cccaaagcct tacgaagacc aatctcacga
    25801 gtgcgctctg tcaccgaaac cagcatgatg ttcatgacac cagttcctcc aacaaagaga
    25861 gaaatccctg cgatggaact aataatcgtc gtcataaaac taaacgattg ttgaatttct
    25921 gcaaatacaa gggactcatc tgccacctgg tattctccct gttgtaagcc tgcaagctct
    25981 gtcatttttc gtgccagttc tggacccaga gttggggtta aactggtatc attcactcga
    26041 aagacaatat tagctatttc atctacatta aaattcgcag caagggagat attggtagta
    26101 ataggcaagc caccaaaccc atatattttt gatcttttag cctccggact agtataaacc
    26161 ccaatgaccc ggtaactaaa tccattgact tctacaacct tgttaatagc ctcttgagga
    26221 gattcaaata aactaatgga caattcctca tctagcaaaa taacacttgc aaactctttg
    26281 aaatcttgct ctctcagact acgacctgca ataatttcat tcttaacagc gtccatgtaa
    26341 gttctgtttc cacctgtcaa attagcattc tcaacctttt tatcttgata ggtcaagatg
    26401 gcattcgttg aattggttac atagtaacta tccactccct tcagtttagc tgcctcttgg
    26461 acccaggatt cttgcggttt tggcggttca acaggaactt cctcttcctt tccagaaacc
    26521 gtaaaagctg attgtttctg agtaaaagac ccatctttac tttttttagg agagaaaaag
    26581 acgctaatat ttttctgaga tttagtcata tctttattga cttgacgaga tagggaatca
    26641 cccaaagcca taatcacaac aactgatgaa acaccgataa taatcccaat catagtaagc
    26701 aaagaacgca tcttgtgagc catgatagat gaaaaggcaa atttcagatt ctgcatctta
    26761 gttttcctcc tttcctaact gagcactgtc agacgaaatg accccatccc gaatgacaat
    26821 ctgacgtttg gcataggcag caatctcagg ctcatgcgtt accatgataa tggtttttcc
    26881 ttctttattc aaatcaacca ataattgcat aatttggtta cctgttttgg tatccaaggc
    26941 tcctgtcggt tcatccgcta ggataataga aggattgttt accaaggcac gcgcaatggc
    27001 tacacgttgc ttttgaccac cagataattc tgaaggtaaa tggtgactac gttctgtcaa
    27061 ttcaaccttg tctaaatatt cctcagccaa cttgcgacgt tttgaagacg aaactcctgc
    27121 gtaaatcaag ggcaattcta cattttgcag agcattgagc ttcgatagaa gaaagaactg
    27181 ctgaaagaca aaaccgattt gttggttacg gaccttagcc agttgttttt caccaagccc
    27241 agccacttct tgaccttcaa gataatattc tccactggtt ggtgtatcca acatgccaat
    27301 cgtattcatc agagtggact taccagaccc agatggtccc atgatggcta caaattcacc
    27361 ctcattcact tctagattga tatttttgag aacctgcaat tcttggtcac cattacggta
    27421 gcttctgaag atatttttta gactaattag ttgcttcatc agtcttcacc tcttttcctt
    27481 cttccaagga agatgttgga ttactgatga ccttagcacc attcgttaaa ccagaagtga
    27541 tttcttgatt ttctgcgtca gcatttccca atgaaacctc aactttttta gccttttgtt
    27601 gttcatccac aatccagaca taatttttac tatcatccat tactagactg ctaacaggaa
    27661 caagaatagc cttagttttg cttttaacct caatgttgac agaaaaaccc tgtttcaaat
    27721 caccaacctc gcctgtcaca tcaatagtat aagggtattt agaacctgta ttatttccgg
    27781 ctgctggact agctgcttca ccattgtttt taggatagtc agaaatatag cttaatttcc
    27841 cagtccattt tttatcagga tacactttag aagtaaagct tacttcttga cctacagaaa
    27901 ggttggctag attgtactca gacaattctc ccttgacttg taaattttca ttgctgacaa
    27961 tatgaaccat aacttggctc gcccctgttg gagatttaga aacattgcta ttgacttcga
    28021 ctacagttcc ctctagggta ctgagaacag ttgttgcatc caattgactt tgagccttgc
    28081 ttaattgcgc cgcagcatct gcacgcgcat cacgggcatc acccaattga gcgtcaatag
    28141 aagcaacaga atttccagcc actggagttg ggctttgcac cgttgcatct tctcctccta
    28201 ctggcgctgg taactgtgga gccggagctg aagcggcttc atttcgtgct tgattgagtt
    28261 cattgatatg acgatctgcc ttagctactg ctcgactagc tgaatcatag gccgcctgcg
    28321 cttctgaact actgtacttg actaaagcct gcccttcgct gaccttatcg cccacagaaa
    28381 caaggatttc atctaaatca cccttactag catcaaaata aacatattgt tcattttttg
    28441 ctgttactgt ccctgacaat aaaacagagg atgccacgct tccttccttg gcaacaacaa
    28501 gatgagtagg ctcatctttt agagcagtct gagaaggttg tctaaagagt aaaatccccc
    28561 cggcacccaa tacaactaca ctcgcagcac cgattgctgc atacagttgc cactttttag
    28621 ctttaccatt ctttttcttc ataatgaaac tccttttctt ttttacaata ctttgctatt
    28681 ataccaaatt tccctccagc aaacaatgca gttcagatgg aaataatggc agttcaggat
    28741 taaacaatcg ttcggaattt tacttttcta ttgtactaga tatataatac actatcttaa
    28801 cttatttggc aagctttttt gcaatttttt gtgcgtagca gatttttgca atcaaatcaa
    28861 aaaaagaata aaatataact atcaaaaaag acgctctact atttaaaaga ttacaaagga
    28921 gttttcaatg agagaatatg atatcattgc tatcggtgga ggtagcggag gaatcgctac
    28981 catgaaccgt gctggtgaac atggagccaa agcagccgtt attgaggaaa agaaattagg
    29041 tggaacctgt gtcaacgtcg gttgtgttcc taaaaaaatc atgtggtacg gggcgcaaat
    29101 cgctgagact ttccatcaat ttggagaaga ctacggcttt aagactactg atcttaactt
    29161 tgactttgca accctacgtc gcaatcgtga agcctacatt gatcgcgctc gttcttctta
    29221 tgatggtagt tttaaacgca acggtgtaga cttgattgaa ggtcatgctg aatttgtaga
    29281 ttctcatact gtaagcgtaa atggtgaact gattcgtgct aaacatatcg tgattgctac
    29341 aggtgcccat ccaagtattc ctaatattcc tggtgctgag ctaggtggct cttctgatga
    29401 tgtatttgcc tgggaagaac ttccagagtc agttgccatt ctaggtgctg gttatatcgc
    29461 cgttgaatta gctggcgtac tccacacttt tggtgtcaag acagatctct ttgttcgccg
    29521 cgatcgtcct ttacgtggtt ttgattccta catcgttgaa ggtttggtca aggaaatgga
    29581 aagaataaac ttgccacttc atactcacaa agtccctgcc aagttagaaa aaactgctaa
    29641 aggcattacc attcatttcg aggatggtac cagtcacaca gctagccaag ttatctgggc
    29701 tacaggtcgc cgtccaaacg ttaagagctt gcaacttgaa aaagctggag tgactctgaa
    29761 tgaacgtggc tttatccaag tagatgaata ccaaaatact gttgttgagg gaatctatgc
    29821 tctaggtgat gtaacaggtg aaaaagaact gactccagtt gcaatcaagg ccggacgtac
    29881 cctatctgaa cgtctcttta acggaaaaac tactgcaaaa atggattact caactattcc
    29941 aactgttgtc ttttcacacc ctgctatcgg aactgttggt ttgacagaag agcaagctat
    30001 taaagaatac ggtcaagacc aaatcaaggt ttataaatca agctttgcat ctatgtactc
    30061 tgcttgcact cgcaaccgtc aagaatcccg tttcaaactc ataacagctg gttcagaaga
    30121 aaaagttgtc ggacttcatg gaattggcta cggcgttgat gaaatgattc agggatttgc
    30181 cgttgctatc aaaatgggag caaccaaggc tgactttgat gcaactgtgg caattcaccc
    30241 aactgcatct gaagaatttg taaccatgcg ttaatcgaaa caaaagaagc tgatataaat
    30301 atgtctgctt cttttttaat gattttcgaa tcaacaaaaa aattatccaa cttgactagt
    30361 cacgaaaatc ggctgttaca gtttttgtta ccttgttttt aaaaaatggt tgacatcgac
    30421 tcctatatga gtataatagt tactatacat tagaaaagag gttaactatt ttgaaaaaag
    30481 ctcacgttta tgctatccct gctattgggg ctgctctcat tgctgctttg gcacaaatca
    30541 gtcttccaat tggacctgtt cccttcactc tgcaaaactt tgcaatcggc ttgattgcta
    30601 ctgtctttag accgagagag gctgtacttt ctgctggact ctatcttctt ctaggtgcta
    30661 tcggtcttcc tgtctttgca ggaggtggag ctggttttca ggctttagtt ggccctactg
    30721 caggctatct ttggttttat ctcgtttact ctggacttac ttcctctcta accaacagca
    30781 agagtggtgt tgttaagatt tttcttgcaa acctcttggg tgatgccctt gtctttgtcg
    30841 gcgggattct cagcttgcat ttcctagctg gaatggcatt tgaaaaagct cttgttgtgg
    30901 gggttcttcc ctttatcatt ccagaccttg gcaaacttct ggctattagt tttattagcc
    30961 gtcccctact tcaacgcctt aaaaatcagg cttactttac taactaaaaa aggataccga
    31021 gttatcatga ctcaatatcc ttttctttta ttttgaaaac ttatactcaa tgaaaatcaa
    31081 agagcaaact aggaagctag ccgcaggctg ctcaaaacac tgttttgagg ttgtggatga
    31141 aactgacgaa gtcagtaacc atacatacgg caaggcaaag ctgacgcggt ttgaagagat
    31201 tttcgaagag tattagttgc ctttaaaggc atccaccatc gtttgaaatt cttcatttga
    31261 gagagtaatc cctttgccca ttttagtatg gtctggactc caagcacgaa tatcaaactt
    31321 tgcaggggca ccattaaagc tcacacggtt aatttccttg gtccaacctt tttcgttttc
    31381 agaaagagtc aacaagtgct cttcgatttc aaatgtaaat tctgccattt tcttctcctt
    31441 ttttagtttc attagtttat tcgtaaaatc ttgtagattt taggaaaatt ttatataata
    31501 ttgatataaa agaagggagg ccaatatgag acataaattc cagcaagttc taaataaaat
    31561 acatgatttt ttaaatggat atgaccaacc tgaccagact gaaaccaact cccttacagc
    31621 cactattgaa gaggctatcc agaaacaaac cgctgttcac cttatcttgt ctgagacaag
    31681 ctttacaggt gacatcatca aatatgatca gcaaggccag caaattatcg tgaaaaattt
    31741 ttccaaaaat gtgagccgga ttatccgtat aagcgatatt caacgcctgc gatttgtccc
    31801 ctcaactgtc caaacagccc aaaaaaatag atttaagaaa gagtgagatg tagttgcttc
    31861 atcccactct tttttcttag cgaatttgtt caaaatgtaa atgaactgcg atatgatctc
    31921 cataaccact tctttccaag tcacgttgta aacgatagga aatgtagtgt tctgcaatgg
    31981 taatgtaacc tgcgcccaat aaacgatgtt caaccataga ttgaatcata ctgatagtcg
    32041 cacgttccac cttggcttct tgtaaatcca aaactacctt cttagtgact tgagcaagat
    32101 tttgacgcaa atcatctgtc aaaacataaa cagtttgggc tgccttcaag atggcttggt
    32161 aaatcttatc tggattaaat tcagcaattt cgccattacg tttgattact tgcataggtt
    32221 tctcctttat tctttgtttt ctttgatttc tgccagcatt ttttcttctt ctactgtcag
    32281 ttgataatgt tcaagtaaat ccggtctgcg ctcgtaggtt ttctttaaac tctcgtacaa
    32341 tcgccactga cgaatctttt catggtggcc actcatcaat acatctggca cgaccatgcc
    32401 tcgataatca tagggacgtg tgtactgagg atattctaaa agacctgaag aaaaactatc
    32461 atcttggtgg ctagactcct tgccaatcac ttctggaatc aggcgaactg tagcatcaat
    32521 catggtcata gctgccaatt ctccaccagt gaggacatag tcacctaggg aaatctcatc
    32581 tgttaccaag gtcttaatgc gctcatcata accctcatag tgcccacaga taaagattag
    32641 ctcttcctct tgagccaaat cttcagcata agcctgatca aactgctttc cagcaggatc
    32701 aaggagaata acgcgcggat ttttcttttc aatagcatca aaggaatcga aaataggttg
    32761 tactctgagc aacatgccct gaccgcctcc gtagggctca tcatctacat gacgggcctt
    32821 ttcagcattt tctcgaaaat tatgatactg gatatccaag agcccttttt ctcgagcctt
    32881 tccaacgatt gagtgctcca gtggagaaaa catctctgga aagagggtta aaatatcaat
    32941 cttcatcgtc taacccttct aagatttcca catcgacccg tttatttgga atatcaacat
    33001 tgagaaccac tggtgggata taaggtaaaa gcaaatcacg tttgcctttt cgtttgacca
    33061 cccagacatc attagcacct ggttgcagga tttccttgat ggttccaacc aagctatcac
    33121 cctcatagac ttccaaaccg ataatctcgt gatagtaaaa ttcaccatcg tctaggtcat
    33181 tcaaatcttc ctcagcgacc ttgagactgt atcccttgta cttttcgata gtattgatat
    33241 ggtacatatc tttgaattta ataatgtcaa agttcttctg tttacggtgg ctagcgatgg
    33301 tcactgtttg gacaaactga tctttttcat caaacaaagc cagctcagct ccttttttaa
    33361 accgttcttc tgcaaaatcc gtcacagaca agactcgcat ctcaccctgt aatccctgcg
    33421 tattaacgat tttcccaaca ttaaagtagt tcatcttgtc tcctgtaatc tccttttttc
    33481 catcttattc taacaattct cgaataatag ccgcaatttt ttccgattct gaccattgta
    33541 aataatggtg attccctcct aaaatgagtt tagtattgga agtccaatat tctgattctc
    33601 tgtactcttt ttctctataa ggctgacaaa aaacaaatac aggaatatga gcttctatag
    33661 atacatcctc aaaatcttcc tcagtaatct ctccagatat ctgaaattct ggatcttgat
    33721 tttccaactc taagcctttt tcttgcatta attcccagat ttttttattc gtttcaggac
    33781 taaatgttgc ttgagttaag ttcttaaaat aaagttcagg accacactcg tcaatcagcc
    33841 tcatctgctc ttccatttct ggataaggat tttctgaaaa atcagcaaac atgacttttt
    33901 tagttgtcgg ttcaattgct actaaagtct gacgcttaat tggtttctcg agtaatttgc
    33961 aagctaaaat tccactccaa ctatgtgcac aaagtatata ttcagaaatt cctaattctt
    34021 caagtacttc ataaaccgca tctgcaagat tatctagatt ttttccagct tggtcatgaa
    34081 tcggactcct acctgtgttc ggaaaatcaa ttgtcaaata accaattgta ggaggaggtt
    34141 tttcaagtat aagtgaaaaa ttttcataac ttggtagcaa acctgctccg tttagacaaa
    34201 ctagcacttt cttttgcttt tgataagtaa cagagaggct accaatttct gtagatactt
    34261 caaacctctt cataaagaaa tccactgatt ctatataatg aattattaaa aatccttatc
    34321 ctttatttta tcacgttcca aggattttct caagttggag gaaggggaca atatctctac
    34381 tttcccttca ataatccttc caaattatgt ttatgttggt aattaacggc tgcggttttg
    34441 tctttctcaa agacagtctt ggtaaggtca atatgattaa tagctacgat tgcgacggtg
    34501 tagtaaatga tatcagccag ttctctggca agttcctcgt tcgaatccta tcccttcttt
    34561 tcgaccagag cgcctattca aaacctcggc tacttctccg acttcctcca ctaacttcat
    34621 aaaaagacct tcatcagtcc gagactgctg ttaatgttcg attaagtagt cttggaattg
    34681 cctaaacgtt caatctttta tagtatattg aaactagaat agtacacctt tacttctaaa
    34741 acattgttag aaatcgattt gactgtcctg atcgatttgt cctgttatta tttcatttta
    34801 ctatatcttc tattccacac aaaaaagcga gacatccgtc ccgcccttct tatttttcgt
    34861 caataacgat tcttactttt ttgtattcag ttgggacaga gtagacaatc gttcttatcg
    34921 cagaaatagt gcgaccctta cgaccgatta cacgacccac atcgctttga tcaagattca
    34981 aatgatattc caaaaattct ggtgtatcct caatcttgat agttaaggca tctggttgtg
    35041 aaattaaggg tttcacaatc gcaataatga gattttcaat cgtatccatc tgtcaaccta
    35101 ctttaaactt attttgagaa tttagaatcg tggaattttt tcaatacgcc ttcttttgaa
    35161 aggatgttac gtactgtgtc tgaaggttga gctccattag ccaaccatgc aagaacgcgg
    35221 tcttctttca aagttacttg gttttcagca acaagtgggt tgtaagttcc aactgtttcg
    35281 atgaaacgtc cgtcacgtgg tgaacgtgaa tctgctacgt tgatacggta gaaaggtttt
    35341 ttcttagaac ccatacgagt caaacggatt ttaactgcca tttttaaagt ctcatttctt
    35401 taatttttta tttcggtgaa atagctgagc tatttagcac atgttctatt atagcagatt
    35461 tctggcaggt gtcaagaaaa aaacttgaca gactataaat ttcttaaagc atttagaaat
    35521 ttgttagaat aggaaataaa tgtttgaaag atgctatccg tgaatactat tttagaaaaa
    35581 ttttataaag aacaccaagt caaacccttc atatcgcctg aacgagagtt ggatacttgg
    35641 cttctaagtc ccaagcgaaa tatggactta ttagcagatg attcactagc aggagatatc
    35701 attttactat ggagaatcca gtttggtact tttaccactg aaacatgatt ttaaaaactc
    35761 ccattcgaat atgattcaaa attcgcttag aatcaatgtt ttcccacttt ttcaaaaaat
    35821 aaattttcat ctaatttaaa taactttcaa ttaagtgtga attttgctta aaatcattaa
    35881 aaaacacccc atggtgtgaa ccatgaagtg ttgtaaatgc tgtgttgtag ctagttctta
    35941 gcgtttagag aactggctag ctttacgagc tttcttaaga tctggtttcc aaaatacttt
    36001 gagtacactt atggtattga tgcccctaaa catctaaaaa ctctggtaga aaaagggtat
    36061 gctcttgtcg aaacttcttt tgactcactt gaccatctaa ataataccat gaaaaagaat
    36121 atcctgaaga agaagggagt tactggactt tctaaaatga aatcttgcga cctggatcaa
    36181 gcccttcatg agcatttttc agaagaagaa ttagctggtc actttcatgt ccttctatgg
    36241 acttttttac aatggcattg ctatcacacc caatacctat ctaagcgcct ggttcgtaaa
    36301 ctttattgca gctcttcctc taaatttcct aattgttgaa ccaattgccc gttttatact
    36361 aagttctttt cagaaaccat ttactgggga agaagttgaa gaagttgaag attttcaaga
    36421 tgatgatgaa atcccaacta ttatctaagc cagttctgta aactactaat atttgaaatc
    36481 cacttccttt tagggtacaa tggtataaat gaatttttga gaggatcaga atgaaaaaac
    36541 tagcaaccct tcttttactg tctactgtag ccctagctgg gtgtagcagc gtccaacgca
    36601 gtctgcgtgg tgatgattat gttgattcca gtcttgctgc tgaagaaagt tccaaagtag
    36661 ctgcccaatc tgccaaggag ttaaacgatg ctttaacaaa cgaaaacgcc aatttcccac
    36721 aactatctaa ggaagttgct gaagatgaag ccgaagtgat tctccacaca agccaaggtg
    36781 atattcgcat taaactcttc cctaaactcg ctcctctagc ggttgaaaat ttcctcactc
    36841 acgccaaaga aggctactat aacggtatta ccttccaccg tgtcatcgat ggctttatgg
    36901 tccaaactgg agatccaaaa ggggacggta caggtggtca gtccatatgg catgacaagg
    36961 ataagactaa agacaaagga actggtttca agaacgagat tactccttat ttgtataaca
    37021 tccgtggtgc tcttgctatg gctaatactg gtcaaccaaa caccaatggc agccagttct
    37081 tcatcaacca aaactctaca gatacctctt ctaaactccc tacaagcaag tatccacaga
    37141 aaattatcga agcctacaaa gaaggtggaa accctagtct agatggcaaa cacccagtct
    37201 ttggtcaagt gattgacggt atggatgttg tggataagat tgctaaagcc gaaaaagatg
    37261 aaaaagacaa gccaactact gctatcacaa tcgacagcat cgaagtggtg aaagactacg
    37321 attttaaatc ttaaaaacca aaaaaataca gtatccacat tcggtactgt atttctttta
    37381 ctctcattct taagttaaat tattaaaatc ccatatttgg tctatccaac cttcataaaa
    37441 gtctggctcg tggcagacca taaggataga tcccctgtat tctttgagag cgcgtttgag
    37501 ctcatccttt gcatccacat ccaaatggtt ggtcggctcg tccagcacta aaacgttgtt
    37561 ttcacgattc atcaagagac agaaacgaac cttggcttgc tctccccctg ataatacttg
    37621 aatctggctt tcaatatgtt tggttgtcaa accacaacgg gcaagggctg cacggacttc
    37681 tgcttgatta agggcaggaa aggcattcca gacagcttca agaggagttt ggcgattacc
    37741 gccttctact tcctgctcaa aataaccaag ttctaaataa tctccacgct ccacttcccc
    37801 agcgattggc gagataatgc ctaagagact cttcaagaga gttgtttttc caataccatt
    37861 agcaccaata atcgcaacct tttgattgcg ttcgaaggta agatttaaag gcttagtaag
    37921 aggacggtcg taaccaattt gcaagttctt ggcttggaag ataaagcgcc ctggtgtacg
    37981 agctggtttg aaatcaaagg atggttttgg tttctcactt tggagttcga taatatccat
    38041 cttatccaat ttcttttgac gagacatagc catattacga gttgcaacac gggctttatt
    38101 acgagccaca aagtccttga ggtctgcaat ctctttctgc tggcgttcgt aggctgcctc
    38161 tagctgagat ttcttcatag cataaacttc ttggaactgg tagtagtcac cagagtaacg
    38221 cgtcagctgt tgattttcca catgatagac aatattgata acgtcattga ggaatggaat
    38281 atcgtgcgaa atgagaacaa aggcattctc atagttttgg agatagcgct tgagccaatc
    38341 aatatgctca gcatccaagt agttggtcgg ctcgtccaac agcaaaatat caggcttttc
    38401 aaggagaagt tttgccaaaa gcaccttggt tctttgccca cctgacaaag aagttacatc
    38461 cgtatccatg ccaaagtcca taacaccaag agcacgcgct acttcgtcaa tcttagcatc
    38521 caaggtatag aaatcacgac tctccagacg gtcttgaagt tctcctactt cttccatgag
    38581 agcatcaaca tccgcgccgt cttcagccat tttcatatag aggtcattga tacgagcttc
    38641 agctttgaaa agctcatcaa aagccgtacg gagaacatca cgcaccgact gtctttcagc
    38701 aaggacagag tgctgatcca agtaaccagc cgtcacatat ttggaccact caacctttcc
    38761 ttcatctggc agcattttac cagtcacgat actcataaag gttgattttc cttcaccatt
    38821 ggcaccgacc aggccgatat gttctccctt gaggagacgg aaggacacat cttcaaaaat
    38881 tgcacggtca ccaaaaccgt gactcagatt tttaacttct aaaatactca ttttaattcc
    38941 ttatcttgtt tttatgtaat cgtttataaa ggagccaagc cagatagcca cccaaagtat
    39001 tggtccacaa atcatcaatc tcaaagacgc gattgaaatc aaagaaaaag tccaagatta
    39061 attgcgtaca ctcgattcca agactcacaa gaaaactaaa aagaaggacc ttttttgttt
    39121 tccgcaaatt tggaaataga taaaggagtt ggaaaatcag aggaaaaaat aagaagacat
    39181 tgaggacatt ttgtaaaaaa atccaacata attgtccaat gtcactcact tcgcccagtt
    39241 tccagagaga attgaaagga gtcaaaagaa aaaccaggcg tccaagatgc tgaatacctg
    39301 gagttcccac tctcacggta gattgttctt gaggagtaaa gcaaaaatag acaatgcaaa
    39361 tgctatagaa aatgactccc cagaccaaaa tatgattata agtcttcttc atcattaagg
    39421 atttaccgct gcgactgcct tctggcggtc acgtttcatt gtgttagagc gcaattgtcc
    39481 acaagctgcg tcaatatctg taccatgctc ttgacgaacc acacagttga cccctttttt
    39541 cttaagcgta tcatagaaag ccaacacgcg ctctttggga ctacggctat attggtcatg
    39601 ctcactaact gggttataag gaatcaagtt tacataagac aatttcttga tgttcttgag
    39661 caattcagcc aattccaagg cttgttctac accgtcgttg acttcattaa gcatgatata
    39721 ttcaaaggtt acacgacggt ttgttgtctc aatatagtat tcaatagcag caaagagttt
    39781 ttcaatcgga aaggcacggt taattttcat gatacttgaa cgaagttcat tgttgggtgc
    39841 gtgaagagac acggcaagat tgacctgaac cccttcatca gcaaagtcac gaattttatg
    39901 agccaaacct gaggttgaaa tcgtgatgtg acgagcaccg atagccattc ctttatcatc
    39961 attgatagta caaacgaaat tcaagacatt gttgtaatta tcaaagggct caccgattcc
    40021 catgacaacg atatggctga tgcgttcatc ctgaccacgc tcatcaaagt atttctgaac
    40081 cagcatgatt tgcgctacga tttcaccgtt attgaggtca cgctgcttct taatcaaacc
    40141 agaggcacag aaggtacaac cgatattaca gccgacctga gtggtcacac agacagataa
    40201 accatagtgt tgacgcatga gtacagtctc aattaacata ccgtcgggca attcaaagag
    40261 atatttgact gtaccatcag cagactcttg cacaatacgt tgtttcaagg gattgaccac
    40321 aaactggtca ttgagcttag caatcaaatc cttggaaagg ttggtcattt cttcaaatga
    40381 ctgcacacgt ttacggtaga gccattccca gatttgatct gcacggaatt tcttttctcc
    40441 ctgctccaat acccattcct gcatggtttg atgtggcaaa ctatgaattg agggtttcat
    40501 ttcttctcct tattctctac tcacttctga cgaatgacaa aatgacgttg tcccttgtcc
    40561 tctttctgag aatgctggtc tttctgacga cgtctatttt tcttatctgc attcgacttt
    40621 cgtttagttt gagtcggttt ctttcctttt ctagaaggtg tttcttcttc cgtcttacgc
    40681 attttcttgt caaatgatgc tcgcttaggg gcttcatttt ctaagacaaa ataggcacaa
    40741 ccataactac aatactctaa aaggtagtct tgtaaacgac tgattttttc aagtttttct
    40801 tctgttcggt catccttgta aaaacctcgt aggcgaagct gttcgttgct ccagtccccc
    40861 acgatataat caaacttggt taagacttct gaaaaacgct gattaaaagt cgtcacatca
    40921 aaggcatcct tgatattttc aaccaaggaa aaagctatcc cttccgtttc gaccttgtcc
    40981 ccgtgtaaat ggaactccgg accaggaaac ttgttatagt tgtataattc aggtgcaatt
    41041 tcttttcgca tagatatcct ttttccacga ttacttaata ctttattcta ccataatttc
    41101 tagcagttag cacgtttctc ataaaaatga aaaaagtctg acgattttgt cagaccagaa
    41161 tcttataacc taaaaaagag aagaacaatt cttccctcca actatcatta tttagcagct
    41221 gcgtacaatt catctacttt attccagttg attactgaaa agaaagcttt gatgtagtca
    41281 ggacgcacgt tgcggtattt cacgtagtaa gcatgttccc aaacgtccaa gcccaagatt
    41341 ggttttttac cttctgagat tggtgtgtct tggtttgctg ttgaagtcac ttcaagtttc
    41401 ccttctttgt tgacaaccaa ccatgcccaa cctgaaccaa aacgagttgt tgctgctgca
    41461 gtgaaggctg cttggaattc ttcaaatgaa ccaaatgttg catcgattgc tgctgccagt
    41521 tctgctgaag gagctgtttt ctcgggagtc atcaattccc agaaaagagc gtggttcaag
    41581 tgtcctccac cattgttgat aagtgcttga cggatatcag ctgggataga ttctacatca
    41641 gcaagcaagg cttcaaggtc ttcaccgatt tcagggtgtt tttctaaagc tgcattggca
    41701 ttgttgacat aagtttgatg gtgtttgtca tggtgcaaat gcattgtttc cgcatcgatg
    41761 tatggttcca aagcgtcgta tgcatatgga agttctggta agataatagc catctgtaat
    41821 acctcttttt ctttctatat gaaaatgata acgcaaacat tcactttttt caagtttttt
    41881 gcttatagat aaggaaagca ctgacatact ttctaataaa ataagcaaat cagcaagaaa
    41941 cccacgacaa gataatcctg acgcgggttg tagtttcaac aaatgtcaat tgacctgact
    42001 agcaatctgt aagagtgcct tttcaaaaag gaaacctttt tcataaagac ctgtcttaat
    42061 ctgatagtct gtctcaatca aataggaaat agcttgcttc agaaagctca aagaaagtcc
    42121 tctcgaatct cttaatgcaa acttgatttg ataaggattt gggttacgtc ccagataact
    42181 acctaaacta cttgcaatct gcgattctgt ttggccagac tccgccaaaa tcttcacctg
    42241 agtaaaagtc cgaaattgtc ccaacatgac cgcaatcagt ttgatttcat cttccccttg
    42301 caaggtcaag tctctcacca aatcgcgcgc ctgatccatc tttttagtca gaataaactg
    42361 agttaaatca aaaatattgt cctgcaaggt cttgggaatt gcgttaacaa tatcctcttc
    42421 ctcgataaca gaatccacct tataggactg taaaaagaga agatttttct ggatttcgct
    42481 aaattgaaac cccgacttga tgaggagatt ttcaaaagaa tgattggtaa actgcagacc
    42541 ttgtttctga ctccactttt ggaagtactg gcgcaattct tgttctttta cttctactgc
    42601 atcgaagacc ttggcatcac gcttaagtaa tttgactaac cgtcttttgc tatccagctt
    42661 tccttctgca aagattatca acttggttgt tggagaagga ttgtcaaggt attcctcaaa
    42721 tgacttaagc tcatcatctg tcaaaaagcg tttcttagca gtcgtgatat ccataaaata
    42781 atctaatatc acgattttct catccgcaaa gaaaggaagg ctgaccaact ccagttccac
    42841 atccttgtaa actacttctt tcatatcaaa gtaggcaaag ttgaggtcag cagaatcata
    42901 cccaatctgt ttcaacactt gactcttcat cacttcaaac tgaccctgat ctgtccctgt
    42961 aaataggctc aggctcggta aatttgataa agtcaacttc tgactttctt caatggctag
    43021 catcgtctct cctttcttca gatttttcga tttaatttag tcaatatagc gcaatttccc
    43081 acggaaatct tctaagctct cgtagccttt ttccaccatg attgctttca gttcattggt
    43141 aatgcggtca aaagcactga cgccttcttt gtgaagggtc gttcccacct gcaccatact
    43201 tgctccacag aggatgtgtt caaaggcatc tcgaccagtc agaacgccac ctgttccgat
    43261 aatttggatt tgaggattta aacgttgata aaaggcgtga acattggcta gagcagtcgg
    43321 tttgatgtat tctccaccaa ttccaccaaa accattctta ggccgaataa cgacagattc
    43381 gtcttctata tagaggccgt ttccgataga gttaacgcag ttgacaaact tgagcggata
    43441 tttgttgaaa atagctgccg cttgatcaaa gtgaacaata tcaaaataag gtggcaattt
    43501 aattccaaga ggtttggtga agtaagcaaa cacttctgcc aaaatccggt ctgttgtctc
    43561 aaaatcatag gcaatctgag gtttacctgg aacatttgga caggaaagat ttagctcagt
    43621 cagaccacga aaatcactct cttggacttt tttcaaaata gtatgggttt cctctggaga
    43681 catgccgacc agagataaga agaaagttcg gttcgactct ttttcctgca aatctaaaag
    43741 ataatccaaa taatagtcta agccattatt tggcaagccc atagagttga tggaaccaag
    43801 tggaacatct tggtagcgtg gctcaggatt cccctgacgg aagtccaagg tcgctgtctt
    43861 agtaacaaag gttcctgccg ctgagttttt gacctcttct aactcctcta tcgtcataca
    43921 agccacacct gctgcattca tcaagcaatt gtcaaactca aaaccagcaa tttgtgtttt
    43981 cgttgatacc atgattctaa tcctccagat ttcttttatt gctaatatta taccataatt
    44041 ttaattctag gtttactaga ttctgtggtt ctatctattt attcggaaaa gaaagtctag
    44101 tacagaagtc atgctatgga aacagctagt gtattagaag tttgaacaag gcttgggtaa
    44161 cagacttttg aatgaagtcc aagcaacaag gagaaatctc aaccatgagt ccattccatg
    44221 actctgttgc tctagaaaac cttgcaatag tcaagtgata acgaataaaa ctttggattg
    44281 aaatatcccc atgattatct attacgagga gaaatctcaa cctttatcat ttttagagaa
    44341 atatagtaaa atgaaacaag aacaggagaa atcgatcagg acagtcaaat cgatttctaa
    44401 caatgtttta gaagttgagg tgtactattc tagtttcaat ctactataca tgtaaatctc
    44461 tactttcgca aaatggattt tcagaatagt atcccagtat agttaaaaac tataaaaaag
    44521 agaggacgtt cccctcttaa aatcttattt tactgcttct ttcaaagcat ctaccttatc
    44581 caaacgttcc catggaagat caatatctgt acgtcccatg tgaccgtaag ccgatgtttg
    44641 acggtaaatt ggacgcttaa ggtccagcat ttggataatc cctgcagggc gaaggtcaaa
    44701 gatttgacga gccgcttttt caagttgact ttcagctact gttcctgtac cgaaagtatc
    44761 gatacgaaca gaaacaggtt gcgcaacacc gatagcatag gccaactgca cttctgcctt
    44821 cttagcaagg cctgctgcaa cgatattctt ggcaatatag cgagccgcat aagaagctga
    44881 acgatccacc ttagtcgcat ctttaccaga gaaggcacca ccaccatgac gagagtagcc
    44941 accataagta tctacaataa tcttacgacc agtcaaacct gagtcccctt gaggaccacc
    45001 gattacaaaa cgacctgtcg gattgataaa gaattttgtc ttatcatcaa gataagaaga
    45061 tggaataact tctttgatga ccttgtcaat cacatcttga tggatttgtt cattagtggc
    45121 ctctggatca tgctgagtag aaataacgac tgtatctaca cgtaccggac ggtcattttc
    45181 atcgtactca actgtaactt gtgattttgc atctggacgg agatagctaa tttctccaga
    45241 cttacgaagt tctgccagac gacgaaccaa tttatgactg agtgcaattg gcaatggcat
    45301 gagctcttct gtttcatcta ctgcaaatcc aaacatgagc ccttggtcac ctgctccaat
    45361 caagtccagt ggatcttgat cagcatttcc acgaacctcc aaggcttcgt taacaccttg
    45421 agcgatgtca ggagattgtt ccaccaaaga tgggtgtact cccaccgtct cagcagaaaa
    45481 tccatattct gtattggtat aaccaatctc tgcaatggta tcacgaacca cacggttaat
    45541 atccacatag gcatttgtag aaatttcacc aaaaacgtgg acagaaccag tatatacagc
    45601 tgtttcagca gcaacgtgcg cctctggatc ctttgctaaa atagcatcca aaatcgcatc
    45661 tgaaatttgg tctgcaatct tatccggatg cccctcagat acagattcag acgtgaataa
    45721 tttacgttct gacataaaaa tgtcccccct taaaaaatat tgttatagag ttacaaagta
    45781 ctgataggaa aactcttcgt aataaatacc taccatctta tcgggactat ataactttat
    45841 cattatacca tttttaatcg caatttgcag tctttaatgt agtgtttcga tttagatagt
    45901 tcgttctcat aaataaaaaa gttggagctc agtactccaa caatttctat taaaatgttt
    45961 ggcgtttagc tttacgctct gcacgaccgc gagcgcgatt ttcagcacgc ttggttttac
    46021 ggcgcttttc atcaaccgcc cattgaattt tcttcttata acccggtttg acttttttct
    46081 ttttcttttt aaccaaacca atcatttcga tatcaagttt atcttgtttt ttctcacggt
    46141 tggcacgacg atcacggtca taggtatctt gaaattcccc gtctttgacc atcttaggac
    46201 taaacttgat tcccaatttc tccaactcac ggatatccga gtcatcactt ggctgataaa
    46261 gggtaatagc tgtacctggt aggccatttc gtccagtacg accaacacgg tgaacaaaaa
    46321 aagataagtc ttgcggaatg gcatcattga tgacatggct gacaccttca atgtcaatcc
    46381 cacgtgctgc caaatctgtt gcgacaatat actcaaaatc cagattttgc acctgattca
    46441 tgattcgctt gcgttcacga ggggcaatat cgccatggat ttttgcaacc ttcaagcctt
    46501 gagcagtcag atatgaatgc aattcatcag cacgcgtttt agtgttaaca aaaatcattg
    46561 ccaaatacgg ctgcatcaac tgagtcaact ggtaaatttg agcattctta tcatgtccct
    46621 tggtcgaaat caaccaatta tcaatggtgt cagaaataac cgttttggtc ttaattttct
    46681 ccataacagg atttgataag tattttttca agaatggttg cagtttttgt gggatagtcg
    46741 ctgagaagac catgaattgc aagtcttttg gaagactgcc agcaatctta tcaacagttt
    46801 ccaagaatcc catatccaag gtcatatctg cttcatcaac aacaaatgtc ttggctttat
    46861 gaatagctaa atcaccagat ttaaccaagt cgtagatacg gcctggtgtt ccaataacaa
    46921 tatgaggctg attgctttcc aatttctcaa tctggcgagc cttatccgta ccacccacat
    46981 aattaaccac acgaacttcg acatctgagt gagctgaaat ctgacgcgct acttggtaaa
    47041 tttgagtagc caactcacga ctcggtgcag taatcactgc ttgtacacta tcgctagctt
    47101 catctaattg ctggaaaatc ggtaacaaga aagtatgagt cttacctgaa cctgtttttg
    47161 attctcctac taggtcacga cctgccaaaa caataggaat caacttgtct tgcacctctg
    47221 ttggagttgt aaattttaac tcctccaagg cttctctaat atagttttta aattgaaatt
    47281 tcgtaaatga cataacatcc tcgattctat ctatcttatc aattatacca tattttattc
    47341 cattacagta gtctcactta tttaggctat ttccagtagc ttctctagta agaaaaggct
    47401 ggaattttat agttccaacc tcttttcagt tattatttcc agtttaacat agcattcaag
    47461 ccatagtgat cactcacttg tggactcttg ttaccatcaa atacgacatg taaattttcc
    47521 accgctaact ctttggtagt aaagacataa tcgattcgaa ggggttcagt gttccctttc
    47581 cagccatcaa tttcaggcgg aacagtatag ctaccacttt tctcttgagc aacttcaaat
    47641 gcgtcttgta agcctaatgg actagctaaa atagcttggt aaccttcctg acctgctggg
    47701 ttgttaaaat ctccagctag taaaagtggc ttgttcaatt ttttcaagac agcctcaaat
    47761 cgtgcccatt cttcttggaa acctttatcc caccaagaga gatgaacact ggcaactgct
    47821 agctccttgc catcgactac agtttcagct agggcaacac ggcgagtatg atagtctgtt
    47881 ggatcatcca catctgaaac caaaatttct ctggcttcaa taggtgtttt agacaagata
    47941 gccacacctt cgtggtagcg gtcatagccg atatggttat aagcccaggt ccagtagtaa
    48001 tttttccctt gctctaacaa cttttcaacc aagagtctaa cataatggtc ttggtgaata
    48061 ggctcagctg ctggcaaagc ttgataaagg tcattaacct ccacctctga cgaggtcatc
    48121 tcctgattga tttcttggaa acaaatcaaa tcatagtcct tttcaagaat atcttcaagc
    48181 aaaatctgga atttttcctc tgcttctttc tccatccaac tgtgagtatt gagtgttaaa
    48241 aatttcattc ttttctccca aaataagagg ttggaataca gcttccaacc tcaagtatat
    48301 tacaattcta ctttagcaac tgctgtttta gctgcaagag aacctgtttt ttctaattta
    48361 actgatttaa ttgcatcacc atttgtgaag acaactactg ttgaagtttc acgtcctgct
    48421 gcacggatag catccaagtc agctgtgaca aggagatctc ctgctgcaac tttttgtcct
    48481 tcagcaacat gaactgtaaa tggtttacct tcaagactta ctgtgtccaa accaatgtga
    48541 accaatactt caagacctgc ttccgtcaca ataccaaaag catgttttgt tgggaagatg
    48601 cttgacacag tacctgaaac tggagataca atgtttccat ttgcaggttc tactgcaaat
    48661 ccatcaccca tcattttttg agcaaatact ggatccttta cttgttccaa accaacaact
    48721 tgaccgtctg ctactgagta aacttcctca gtaagatctt tgaagtgaac agtgttttgt
    48781 tgtgcttcag tcatttggct tggaagagtt tcaggaatga tttcacctga atcaaggata
    48841 tcttggatat cagatttcaa aatgtcagct tttggaccgt agatagcttg aaccccttgt
    48901 cctttcatca caagacccat agctccttct gctttccatt gctctgcatt tcctacttta
    48961 tctgcatctt taacagttac acgaagacga gtcatacatg catcaacatc aacgatgttt
    49021 acacgtccac caagaaggtt gataatgttt acagcttgag agcctgctgc aactttcact
    49081 tcgctgctgg tttcttctga accttcagca gtttcgtagt ttccgttgcg ccctggagtt
    49141 gcgtagttga atttttgaat catgaagttt gcgataaagt acatgattac agcaaagaga
    49201 acagttaccc aaacgaagtt aacgatatcc ataccaatac cagcactgat tgcaataggt
    49261 gtacgagtca agaactcgat tgaaccgaat gagtgcatac gtaggtttac gacgtcagcc
    49321 atagcgaagg cagcaccttg aacaagtgag taaacaagat acataggtgt tgcgatgaac
    49381 atgaacatgt attcgattgg ttcagtaacc cctgtcaaga atgttgcaag agctgttgca
    49441 atcatcatac ctttgtattt atgtttcttg tcagcatcaa cattacggta gatagcaaca
    49501 atcacaccca tcaagatacc gaatgaaccg atcatttgtc caactttgaa acgagctgga
    49561 tgtactgtat ctaacaagtg ttgatattga ctagcatcag tacctttaag gtttacaagg
    49621 tctgttaccc atgcaagcca tagtgggtct tgaccgaata cttgagtacc tttagctgca
    49681 ccagttaaaa tgtcataagt accaccaaga gctgtgtagt tcattgggat agtcaacatg
    49741 tggtgaagac caaatggcaa gagcaaacgt tccaaagtac catacaagaa tggtgcaaga
    49801 attggagcag tttcttgtga gttggcaatc cagataccga agttattgat acctgtttga
    49861 actactggcc agaaagcagc aagtagaatt gcagcgattg ctgaacgaag aataactaca
    49921 aatggtacga aacgtttccc gttgaagaat gaaagtgcat caggaagttt acggaagttg
    49981 tagtatttgt tgtaagcagt tgcccctaca aaacctgaga taatccctac gaataccccc
    50041 atgttcaagg ctggagcttc aagaacactg ataaagtaat cagcaacttt gattgaacca
    50101 ccaaagaaag tagttaccat agcatctgga tttttcaaca tatcgcctga tacaccaaaa
    50161 attgtaccag tgatacggtt aatcaagatg aaggcaagac cagcggcgaa agcaccacca
    50221 gcacgttctt tagcccagct tcctccaatg gctagggcaa acaaaatgtg aaggttaccg
    50281 ataacccccc aaccgatttg ctcaagaatt ccacctgtga tgacaagtgg tgtaaaggtt
    50341 gggttaatca tcacgataga cttaccgatt gaaatcatca aaccagcagc cggcataacc
    50401 gcgataacta ccatcaaagc cttaccgaat ttttgccaaa attcgaaaga caagacattt
    50461 ttgaatgtat ctttcatcat tcaaatctcc tttattttta tttaggcaaa cgttttacga
    50521 aaacgtttgc accttctata atttaattat accactttaa ttttttttgt aaaggctttt
    50581 ataaaaaaat tacacttttt tctaaaaaat ttctagtgag tcaaatttca agttcaaatt
    50641 agccatcaag aagtcttctc tgggggactt ctttggaagc tcttttcttc tgcgcatctc
    50701 ttttcaaaaa ctcttgtagc aaaaaaggag attttacaat ctcctcataa aagcagctat
    50761 tttacctaaa tcttcaagaa tcggcgcatg gatattcctg atcccaatga accaatgaaa
    50821 accccaatca caaatagtag ggcaatcatc aacggactaa ataaatctgg actaatcatg
    50881 gatagatttt gccctaccaa cgatttgttg acagattgat aaacaatttg ataaacaata
    50941 aagaccaaaa cagatggtgc gatagctccc aataaaccga taaaggctcc ttctaacaag
    51001 aacggtccac ggatataact gtttttagct ccgaccaagc gcatgatttg aatttcgcga
    51061 ctgcgggaaa taatggtaat acgaatggta tttgaaatca aaaaaactgc gataaaaatt
    51121 aacaaagcag caatccctag tccccaaaca cggataaatg aagctaactt gaagagtctt
    51181 tctgtattgg caccgccatc ttgaacctca gagacacctt caattttttt agcatcttcg
    51241 gctatagttt ttacatcatt tggagtgttt gcctctacaa tataggcatc atagagagga
    51301 ttggcatctc cttcaaagat tttccagtta tctcccatta tctcggttaa tttttcatat
    51361 tgttcttctt tacttgaaaa ggtaacactt ttaaccgtag acatgttctt caaagaatca
    51421 tataccttgt ggtagtcatt atttgtaaca gtttgacctt ctttttcaat tgtctgacta
    51481 ttatcttcca catcctttcg gatataaact actacacgga cattattttc aatatctgta
    51541 gctagtttcg ctgtattgaa aataacagat gcaaatattg ccaccaaggt caaagtaatc
    51601 atgactgaac tgacagcagc tactgtcatc caaccatttc gtttcaaact ttttaaggct
    51661 tcaaataaat ggcgaaaaaa tctactaatc atcgtatcca tactctcctt ttgattcgtc
    51721 acgaacgaca cggccatttt caatggcaat gacacggtgg cgcaaggtat ttacaatctg
    51781 gctattatga gtcgccatca aaatagttgt tccttgtagg ttaatccgtt ccaagagatt
    51841 cataatttcc catgaattat ccggatccag atttcctgtt ggctcatcag ctatcaatac
    51901 tttgggatta tttacaattg cacgcgcaat cgcaattcgc tgttgctccc cacctgagag
    51961 ttcatttgga aaagaacgaa ccttatgctt caatccaacc aagtccaaaa cttccatcac
    52021 tcgtcttttg atattacggc gattttcccc gattacttcc atagcgtaag caatattttc
    52081 atagacagtt ttctttggta acagtttata atcctggaag acaaccccaa cactacgacg
    52141 tagaagcggg acatctttct ttttgatctt aaccagatta aaaccagcaa ctgataggct
    52201 tcctttatcg atttttactt cacgatacag agaacgaata aaagttgact tccctgctcc
    52261 tgaaggtcct acgatgtaag caaattcccc cggttgaacg ctaaccgaaa caccgcgtag
    52321 agcagttgtt ccgttgtcgt attttttaac gacatctctc atttcaataa ttgacatgtg
    52381 agttcctttc tatcttagct aattcgccac ttgagataag catcgataaa accatctagg
    52441 tccccatcca taaccttatc tacctgagca acctcaaagc tagttcggtg atcttttacc
    52501 atagtataag gcgtgaagac ataagaacgg atttggcttc cccaagtgat ctcctttttc
    52561 tcacctttga gagaatctac ctccgcagcc ttcttatctt gctccatttg atagagctta
    52621 gcctgcaaca tcttcatggc acgatctcta tttccatact gggtacgatc cactgttgat
    52681 tggacaacaa ttccagttgg aatgtgggtt aaacgtacac ctgttgaaac cttattgacg
    52741 ttttgtccac cggcaccacc tgaacggaag gtatccatct tgatatcatc ttcacggatt
    52801 tccacttcaa tagtatcatc caattctggc atcacttcta cagatgtgaa agaggtatgg
    52861 cgacgtttgg cagagtcaaa tggtgagatt cgcactaagc ggtgaacacc catttctgac
    52921 ttgaggagac cataggcatt aggcccttca aatgataaag ttaccgactt aataccagcc
    52981 tcatcacctg cttggtaatc caacacttcc actttaaagc ctttagcatt accataacga
    53041 gtatacatac gaagcaacat atcaccccag tcctgcgcct cagtaccacc agaacctgga
    53101 tggatttcca agatggcatt gttgtggtca taaggttctg acaagagtag agtcatctcg
    53161 tagctggtca ttatcttatc aagttcggct aactgcgcta ccagttcatc atgcactgac
    53221 tcgtcttcag ccaaaaaatc caataaaatt tcgacttcat cctgcaactc ttccatctta
    53281 tggaaggtat tgtaagtgtt ttttaattca tttaattctt gcgacgtttt ttgggccgca
    53341 atattatcgt tccaaaaatc aggttctgtc atcttgtttt ccaagatggc aatctcttcc
    53401 tctagccctt cgaggtcaaa gagaccccct gaaagaagct aatttttcac gatttgcgtc
    53461 aattttctga cgaattactg aaatgtccat aaatactcct tttttacatt atttcattat
    53521 agcatatttt atcatttctt tccatctttt tctctaatcc ccttttcatg aaaaaagaag
    53581 cctttgggct tcccttctta caagactttt gctgaagtgc gagcgatttc ttccacttga
    53641 ataccatttg cttcaaattt ttctttcaag gctggtaaat caattgatcc atcgatttgc
    53701 acttcgataa tgaccttacc atccttacgc ggaatattga ctgtatggga gatattcaaa
    53761 ttttcttcta caatcaaaga aacaattttt ccaagaacac caacttcatc ttctgtaaca
    53821 aagcgtacac gaatcccttc ttcgccataa cctgcaattt caagaaaggc ttggaaaacg
    53881 tcacggtcag taataactcc gtatacttga tggttatcta cgacagggag aataccaatc
    53941 ttatttttca acatcagata agttgcatct tctagactag catagcctga gacagtgaca
    54001 acatcgcgaa tcatgacatc ttttactttt gtcttattca gaagataatt catctcatag
    54061 atagaaagac ttgttgcttt agatggactt gcttgtgcaa tggttccctc agtcaccaaa
    54121 ccaaccaatt gatcattttc gataacaggc aagcggtgca attcttgctc tctcatcaaa
    54181 tctgctgcat gagatactgt tgtatctgga ctaatataaa ctaccttgcg ggtcataaaa
    54241 tctttaactg ccatgagact tctccttttc tattcttatc cccattatac aatctttttg
    54301 taaatctatc aaacgcttac atttcttttt cgaaattcaa aaaagtatga ataagctagc
    54361 aaaaagagct ctaaaatcga gctccctgaa tgaaggtaag atacgtttca ttcgattttt
    54421 tcaattatta gaaattcagc tttcaatgta gatgcagatt tgtttgcaat ctcaatctac
    54481 cggctaaaac aatcctctgg atttgatgat tgcttcgcaa tcttcatcca ccgactaaaa
    54541 agggcccccg gactatattg atgattactt cgtaatcttc atctgccgac taaaacaatc
    54601 cactggattg ttttagccac ctagatatgc ttttctgact tcttctgatg aagcgagttc
    54661 ttttcctgtt cctgatagga cgatttttcc tgtttccaat acatatcctc ggtcagagat
    54721 tgcaagtgct ttattggcat tttgttcaat caagaggacg gttgttcctt gcttctgaat
    54781 atcttgaatg atatcaaaaa tctcttggat gaagattggg gcaagtccca ttgatggttc
    54841 atctaaaaga agaagttttg gtgttgacat aagagcgcgt cccatggcaa gcatttgttg
    54901 ttcccctcct gaaagagtag ctgcatcttg gttcttccgt tcttcaagac gaggaaagcg
    54961 tgagaaaacc ttcttcaagt tagcttgatt ttcttcacga tttttcttta agaaagctcc
    55021 catttcaaga ttttccataa cagtcaagcc aggaaagacg tggcgtcctt ctggaacttg
    55081 tgaaagacca cctgccacga ttttctgagc tggcattttt tggatttctt gacctaaaaa
    55141 ttcaatcttt cctgaacttg gtcgaaccaa acctgacaag gtgcgaagaa tagttgtctt
    55201 acctgcaccg ttggcaccga taagggaaac aacttctcct tcattaactt caaagcttac
    55261 atcacggact gcttggatca taccgtaatg cacagaaaga ttttcaactt ttaacataga
    55321 cattaggctt cacctcctag ataagcttcg ataacgcgtt tattggtctt aatttcgtct
    55381 ggagttcctt gagcaattaa acggccatat tcaagtacgt agatacgttc tgttacttcc
    55441 atgaccagat tcatatcgtg ttcaatcaac atgattgtaa tcttaaattc atctttgata
    55501 cgacgaatta actcagtcaa ttcggctgtt tcctgtgggt tcatacctgc tgctggttca
    55561 tctaagaaga gaattttagg ttccgtagca agggcacgaa caatttccaa acgacgttgt
    55621 tgtccgtagg aaagattttt agcaagagtc tctgcatcac catctaaatc aaagattttc
    55681 aacaattcca aagctttatc ctttaattct ttttcactct tgtaaaaagc tggtaagcgt
    55741 aagaaactag taaaaacatg ctgtttgtga tggtttccaa aagcaatcaa aacattatct
    55801 aaaactgtta aatctttaaa gagacggata ttttggaaag tacgtccaag tcccaaagag
    55861 gcaatcttat aaggtgattt cccattcaaa aggtgaccat ctagggttac tgttccctcg
    55921 cttggttcat aaacaccggt caaaaggttg aaaagggtgg ttttcccagc tccgtttgga
    55981 ccgattaatc caaccagttc cccttcgttc aattcaagag tcacatctcc aacagctgtt
    56041 agaccaccaa aatgtttggt taactgtttt acttcaagta atgccattag ttttgttcct
    56101 ccttcttaga ttttttaaag aaacgtgata ggctcagttc ccacgttcca aggagtccac
    56161 ctggtctgaa aatcattacc aataccaagg ccaaagcgta aataatcata cgcacactag
    56221 caacatcttg gagaagcata ttcaaaattc ccagaacaat agccgaaaca atcgcacctg
    56281 taatggaacc gagtccacca aatacaacaa taatcaaaac gttgattgag ttgatgaagg
    56341 tgtaatcttt cggtacaaca gacccgataa atcctgcctg aagtgaccca gcaatacttg
    56401 cagtaatggc accaaagaca aaagcgatga ttttaatttt agtcgtatta accccaactg
    56461 actcagcagc gatttcatct tcacgaacag agagggttga acggccaatt gggctacgca
    56521 agaagttcaa ggttgcaatg gttgtaatca cgacaaagaa gtaaaccatt tgccaagttg
    56581 taaagttagg aatccctaag atacctgccg caccatttgt aagacttcca ccattgatga
    56641 taaagatacg gataatttca gaaacaccca gagttgctac cgcaagatag tcccccttca
    56701 agcgcaaggt tggaatgccg acaagtaagg caactgctcc tgaaagcaaa gcccctacaa
    56761 gcatagctcc aaagaaggca ccgtaggttg gtgatttaga accaataata gctgctgcat
    56821 aggcaccaat cgccatgaaa ccagcatgac caagtgaaaa ttgtcctgaa aaaccaacga
    56881 ttaagttgag accaacagcc aaaataatat taattccaat ttgttgtaaa atctgtacat
    56941 agaatagatt aagtactccg actgaaacca gtacactaat caagctatag ccagctaaca
    57001 aaaggagtaa ccatagaata ttaactttta aattttcctt catcgtttac accttctctt
    57061 tcacattctt accaaggata ccagctgggc ggacaatcaa gatcaacaac aagattccat
    57121 aaacaatggc atcacggaaa tctgacatct caaaggctgt cgcaaaggtt tccaatagac
    57181 caatcacaaa gccaccaaga gccgcaccgg gaataattcc gataccacca agtactgcgg
    57241 caacgaaaga tttaagacct ggagtaaccc ccatcaaagg ctcaagagag ttataataaa
    57301 gagcaatcag aacaccagcc gcacccgcaa gagcagaacc caaagcgaag gtaaagctaa
    57361 tcgtacggtt tacattgatc cccatcaatt gtgccgcgtc gctatctact gatactgcac
    57421 gcatggcttt ccccatctta gtcttttgga caatgacttg taacaaaatc atcaaaatca
    57481 aggaaatggc caaaatcatt aactgcacat ttgttaagct aattgctccc aaatcatatc
    57541 gaactgtttg aatcgcttga gggaaggcac gggtattggc accaaccaga tagaccattc
    57601 catactccaa taggaaagaa accccaatag ccgtaatcaa aacagcaata cgagtagagt
    57661 ggcgcaaagg tcggtaagca agaaactcaa tcacgacacc aagaatagct gtcgctagca
    57721 tagctacaat aagcgctaca aagaaattca tttggaaaga attgatcaag aaataaccga
    57781 taaaggctcc catcatataa atatcaccat gggcgaagtt gatgagcttg ataattccgt
    57841 aaaccatggt atatcctagg gctaacagcg cgtaaacact acctagaatc aaaccattta
    57901 cgagttgttg gagcataaga ttcactcttt ctatttataa ttccgagggt tttccctcac
    57961 tttttgatag gttcttatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag
    58021 gttgctcaaa gcactgcttt gaggttgtag ataagactga cgaagtcagt cacatatata
    58081 atccaaggcg acgttgacgc agtttgaaga gattttcgaa gagtattaaa tatcgaaaca
    58141 gggagtgagt caaaggctca ttccctattt caacattttt ctattatggt tttacaactt
    58201 ctgctgcttc aactttacca ttgttcatgg tcatcatgta agcagttttg actgtgttgt
    58261 ggtctgcatc gaagcttgtt tgaccagtta caccttcaaa atcttttgtt ttagcaaggt
    58321 tattcttgat ttcacctgaa tttttagcac cttttgctgc gtttgctaca aggtgaactg
    58381 aatcataagc caaggctgca aatgttgaag gctcttcatt gtacttagca cggtaagcgt
    58441 caaggaaggc tttagcttta gctgaaactt ctacagtagt tgagaagcct gagataaagt
    58501 agatgtttga tgctttttca gcagttgctt gttgtacaaa ctcctcaccg ttgaatccat
    58561 caccaccaac gattggtttg tcaattccca tgccacgcgc ttggtttaca atcttaccag
    58621 cctcattata gtaaccagga acaacgatag catcaaagtc tctccctttc atttttgtaa
    58681 gggctgcttg gaagtctgtg tcacctgcta cgaaagtttc atctgcaacg atttcaccct
    58741 tgtatgactc gcggaaagat ttggcaatcc ctttagcata gtcactggca ttgtcagtgt
    58801 aaagaacaac tttcttagca tttaattttt cagaaacata gtttgagata atttttcctt
    58861 ggaagctatc ttggaaagtt ccaataaaga ggtaatcttg acctttagtc aatccatctt
    58921 gagtcgcact tggtgagacc aatggaacac ctgcttttgt agcattcgct accgcagctg
    58981 cagtcgcacc agatgtcgca ggtcctacga ctgctgatac tttagattgg gttacaaggt
    59041 tagttgtaac tgaagcagcc tcagctgttt cagacttatt atctttatcg attacttcga
    59101 tttgttttcc atcgatacca cctgcggcat tgatttcatc aacagccaat tgggcacctt
    59161 tttgttcagc tgttccgtat gcagctaaag aacctgattc ttcaaagtta aacccgattt
    59221 taattgtctt ttcctctact gagttaccag cagtgttgac tgctccagac ttcacttctc
    59281 cacaggctgc aagaagtgct acacttgcaa gcgccacaaa cgatagggca aattttttct
    59341 tcatcttttt gtctccttat ttcttaaata gtctgttaag aatataccga attatcagaa
    59401 aattgtcaat gttttccttg aactttttct atgataacgt tttcctatcg ataaagattg
    59461 cccacaaagg gtgtttccaa ctcttggata tgacaaaccc taactttttt aataaatttt
    59521 tccttgctca agcgtccgac caattgctcc acttcttgag ttggaacata gagttgtaag
    59581 taacgatgtt tcttggaatg ataggtaata tctccataat cctgcaattt tttggcatca
    59641 cgattatagt aaagatagat aatcaagcca gagcgattga ctttttcaaa catgataaat
    59701 cctctttcta agaaatctct ccctattata ccaaaaaaag caaacccagt cgagtttgcc
    59761 ttctatcatc attagttcaa tgaattgttg gccataattt catcaataaa gccatattca
    59821 agtgtttcct gggcgctcat ccagttatca cgttctgcat ctgcatggac tttttccatt
    59881 gactgacctg aattttcagc caagattttt tccaaggtat tacgagtttt gagcaagtgt
    59941 tctgcagcga tagccatatc agtttgttgg gtaccaccac ctgtaccgcc cattggttgg
    60001 tgaatcatgt attcagcatt tggaagcatg aaacgtttgc cttttgctcc acttgatgcg
    60061 atgactgttc ccatagatgc agccattccc ataacgatgg tttggacatc tgccttgata
    60121 aagttcatgg tatctacgat tgccaaacca gctgaaacag aaccacctgg tgtattgaca
    60181 taaaggtaaa tatcttttgt actatcttgg gcatccaaga aaagcaattg ggcaataaca
    60241 gagttagcca tattgtcttc aaccggacct gtcagcataa tgatgcggtc tttgagaaga
    60301 cgtgagtaaa tatcgtaaga acgttctcca cggcttgttt gttcaataac tacaggaatc
    60361 attcatttct ccttttgagt tttaattttg ttggtcaaat gactgaagat aagactatta
    60421 taatatcttg gtcaaaaaag gtcaaatttt tgctctgctt tcattagaca gaaacaaaaa
    60481 cccaacctcc tttcgtgact ggaaatactt ttccaagtca ttcttctttt cgatcttatt
    60541 ttgtaccgaa caagcggtct ccagcatctc caagacctgg aacgatataa ccgtgttcgt
    60601 tcaaacgttc atccaaggct gctgtaaaga tttctacatc tggatgagct tcttgaaggg
    60661 cttttacacc ctctggagca gatacaaggc agacaaattt gatatttgat gcgccacgtt
    60721 ttttaagaga atcaacagcc aagattgctg agccacctgt tgccaacatt gggtctacta
    60781 taaaaatttg acgttggtca atgtcctcag gcaatttcac caagtattca actggttgaa
    60841 gtgtttcttc atcacggtac ataccgatgt ggccaacttt agcagctgga accaagctca
    60901 agagaccatc aaccatcccg atacctgcac gcaagattgg gacgatggcc aatttcttac
    60961 ctgccaattg tttttgaact gtttttgtaa ttggtgtttc gatttccaca tcttctagtg
    61021 gaagatcacg aagtacttca taccccatca acattgcaat ctcatctact agctcacgaa
    61081 aagcttttgt agaagtatct gtacgacgca agattgacaa tttgtgttga atcagtgggt
    61141 gattaataac ttcaattttt cccatttttg gaattccttc tttcaattta ttcttcttat
    61201 tataccaaaa aacggtttaa aaatctttct aagccattta tttttgataa tttttacatt
    61261 agatcagcct ctttaagagc tgtctgtact gtctcaagtg gtaaatgggt caattctgtc
    61321 cctttttctt gataaaggta ttgggcgtag tcgtccattc ggtactggtt gatataaacc
    61381 acgcgcttgc agccgacctg aagcaattgt tttgtacagt tgagacaagg aaaatgggtt
    61441 acataggctg taaagccttt gggaacacca cgctcagcac cttgaaggat agcattgacc
    61501 tcagcgtgaa gggtgcgaac acagtggcct tcaatgatca aacattcgtg atcaatacaa
    61561 tgctcagtcc ctgacaccga accattgtaa ccagtggaaa taaccttatt atcttttacc
    61621 agaatcgcgc ccactttagc acgtttacaa gtggaacgat tcgcaattag tagggcttgg
    61681 gctgcaaaat actcatccca ggccagtctt ttttcagtca tcttttttct cctttttctc
    61741 tattttttaa aaaatggtaa acctaaatct gcaatctttt cagctggtac cttcatgcca
    61801 tccttgatcc attttagaag gacagagacg atggctgagc tccagaagga atgaagataa
    61861 gagctgacac cttttgattt cccatggtat ttttctagaa attcctgcat ggcttggaca
    61921 aagatttttt ccagatggta atccaaggcc aattgaatca ctctagcttc ctttctggcc
    61981 tcccggaaaa ggtgaaccca aaccaaataa aggtctgtct ttaaatcgta atgatgcagc
    62041 tgttccataa tattgtggac agttcgttta aagacgctct ctaaaatttc ctctttggag
    62101 tcataattgc gataaaaggc cgcacgcgaa acacctgcac gtttgaccaa ttcagaaata
    62161 ctaatcttgg tcagctcctt tttttccaag agttgcaaga gggctgtttc aatggcttct
    62221 ctggttaata aattggattc ttggtttgat tttctgagat tttcaagaga cttttcagag
    62281 attctacgtt cagacataac attttctttc tacttgtcac aacagacgga tgatgctttt
    62341 gtttcaaggg ttttcatgat ataattgtaa aaaaagacag aacctttgtc aatgtataac
    62401 tgacaaagat ggagaatttc tatgacttgg aaaattattg ctgactctgg ttgtgattat
    62461 cgtcaactgc caacaccagc tattaacaca acctttgtaa gtgtcccctt aaccattcaa
    62521 gtagctgatc aggtctttgt tgatgacgcc agtctcgata ttgaccaaat gatggaaacc
    62581 atgtatgcaa ctgcagaagc ttcaaaatcg gcttgtccaa gcccagatga ctatttgcga
    62641 gcatttgaag gtgccaaaaa cattttccta gtaaccatca caggtaccct ttctggcagt
    62701 cacaatagtg ctcaactagc aaagaatatt tatctggaag accatcctga cactaagatt
    62761 catgtgattg atagtttatc tgctggtggt gaagttgacc tactcgtaga aaaattgaat
    62821 gacttgattg accagggctt gtcttttgaa gaagtggttg aagctatcac cgcctatcaa
    62881 gaaaaaacta agttgctctt tgtcctagcc aaagtcgata acttggtgaa gaacggccgt
    62941 ttgagcaagc ttatcggtac ggtcgttggc cttctcaaca ttcgtatggt cggaaaagct
    63001 agtgaaactg ggactctcga attgctacaa aaagcaaggg gatcaaagaa atcagttcaa
    63061 gctgcctatg atgagttagt aaaagctgga tatgctggtg gccgtattgt catggcccaa
    63121 cgcaataacg aaaaatgttg tcaacagctc tcagagcgaa tccgtgaaac cttcccacaa
    63181 gcggatatta aaattctacc aacctctggt ctctgcagtt tctatgcaga agagggcggt
    63241 ttgctgatgg gctatgaaat tgattaattg cattcttgac aagaggtgac catcatctct
    63301 tgtttttttg tggtacaata gagctatgaa acattttgat actattgtca tcggtggggg
    63361 acctgctggt atgatggcta cgatttccag tagcttttat ggacagaaaa ccctcctcat
    63421 cgaaaaaaat cggaaacttg gaaaaaaatt agctgggact ggtgggggac gttgcaatgt
    63481 gaccaacaat ggtagcttag acaacctgct agctggaatt cctggaaacg gacgctttct
    63541 ttacagtgtt ttctcccagt tcgataatca tgacatcatc aactttttta cagaaaatgg
    63601 tgttaaactt aaggtcgaag accacggacg cgtctttcca gccagtgaca agtctcggac
    63661 tattatcgaa gctttggaaa agaaaatcac cgaactaggt ggtcaagttg ctactcaaat
    63721 agaaatcgtt tctgttaaaa aagtagatga ccagtttgtc cttaagtcag cggatcaaac
    63781 cttcacttgt gagaaactca ttgtcacaac aggtggtaag tcttatcctt cgactggttc
    63841 gactggtttt ggtcacgaga ttgctcgcca ttttaagcat accatcaccg atcttgaggc
    63901 tgctgaaagt cctttattaa cagattttcc acataaagcc ttacaaggga tttctctgga
    63961 cgctgtgacc ctaagttatg gtaagcatgt catcactcat gatttactct ttacccactt
    64021 tggtttgtca ggtcctgctg ccctacgcat gtctagcttt gtcaaaggtg gggaagttct
    64081 ctcactcgat gttttgcctc aactttctga gaaggacttg gttacatttc tagaaaaaaa
    64141 tcgggaaaaa tccttgaaaa acgctttaaa aaccttgtta ccagaacgct tggccgaatt
    64201 ttttgcacaa ggatatcctg aaaaagtcaa acagctgact gaaaaggaac gagaacaact
    64261 tgtccagtcc attaaagaac ttaaaattcc tgtaactgga aaaatgtccc ttgcaaagtc
    64321 ctttgttacc aagggtggag tcagtctcaa ggaaatcaat cctaaaaccc ttgaaagtaa
    64381 gctggtacct ggcctccact ttgcaggcga agttatggat atcaatgccc acacgggtgg
    64441 ctttaacatc acttctgccc tctgtaccgg ctgggtggcg ggaagtctgc attatgatta
    64501 aagattaaag gttgtgaaga atgaacagaa gagaggcagt cgaatttgtt aacatgtgta
    64561 tgattaaaaa cggagataag gtcctggtcc aagaccgagt tagtcccgac tggcctggca
    64621 ttacttttcc tggtggtcat gttgaacgtg gcgaatcctt tgtcgatgct gtcattcgtg
    64681 aagtgaaaga agaaactggt ctgatcattt ccaaacccca actctgtggt atcaaaaact
    64741 ggtatgacga caaggattat cgttatgtcg tcctttttta caagacagaa cactttactg
    64801 gtgaactcca gtcttcagac gaagggaaag tttggtggga ggactttgaa aatctttctc
    64861 atctaaaact tgcaaccgat gatatgtctg atatgcttcg tgtgtttcta gaagaagatc
    64921 tcagtgaatt cttttactac aaaaacggtg acgactggct ttatgatttg aaatcgagta
    64981 ggggataatc tctagcccct ctcacaccac cgtacgtgcc gttcggcata cggcggttca
    65041 actaactttt aacgcatgtc gttcaaggta ataatccaag cacgaaacca gtccacgttt
    65101 ttcaaggact ggttttgata tagcacgttt aagtaccgac ttctgagcta ctaattgata
    65161 atggtcgccc cagccagata ccttatctgc tatccattta ggaaccccta agttaagcaa
    65221 tccccataat cgtctagatt tcttcttcca ttgcttccag ataatcactc ttatgcgtgt
    65281 tctcagtcgt tcatcaatgc tctccatgac tgatttcatg ttcgtcattg aaaagtagtt
    65341 tatccagcct cggataagcc aattgagttt ctcaatacga ttatccaagt caatactcca
    65401 ctttcggcta gtcagtttct tgagttttct cttgaaattc tgtacactgt cttggtgcgg
    65461 gcgacttttc cacccctcgg ctgacttcca gaatccaaat cctagatact tcagtttact
    65521 tggtctcaag tcaggcgcca gttttgtctg agatagccat ccatctcttc gatagtcatt
    65581 ccatcaatcc cagctgagcc tttattggat tttacttgat tgtaggcttc aagcatgttg
    65641 tcacgtgata atattttatc tagcaatttt gacatgtgcg tattcctttc ttgttttggt
    65701 gcctgaggga catcttatat tggtgaacct tcatctagtc aatacgtgac agagtccagt
    65761 tctatcagac cgttcgtttt ccagacacaa gtgaagtagg attacttcga tctgtcgttt
    65821 tctctttcta gcgacagatc tcaaacagtc tctccccaga ctgtttgagt attctcccct
    65881 tcgctccact tccattacag aagtttcctc actactatgg gttcggctga cttctcatga
    65941 ttcgttgtta ctacgctttc agcgctcatg agacctcacg ggataagtcg tacatctttc
//
LOCUS       DAVLZS010000007        60636 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLZS010000007 DAVLZS010000000
VERSION     DAVLZS010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.007"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(132..230)
                     /locus_tag="VYO88_000424"
                     /pseudo
     CDS             complement(132..230)
                     /locus_tag="VYO88_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(301..2049)
                     /locus_tag="VYO88_000425"
     CDS             complement(301..2049)
                     /locus_tag="VYO88_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718587.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTMDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIAEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(2051..3775)
                     /locus_tag="VYO88_000426"
     CDS             complement(2051..3775)
                     /locus_tag="VYO88_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718588.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLLPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGVSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDVLVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3833..4771)
                     /gene="msrB"
                     /locus_tag="VYO88_000427"
     CDS             complement(3833..4771)
                     /gene="msrB"
                     /locus_tag="VYO88_000427"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1718589.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4913..4990)
                     /locus_tag="VYO88_000428"
                     /pseudo
     CDS             complement(4913..4990)
                     /locus_tag="VYO88_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5066..5935)
                     /locus_tag="VYO88_000429"
     CDS             complement(5066..5935)
                     /locus_tag="VYO88_000429"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1718590.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(5937..7223)
                     /locus_tag="VYO88_000430"
     CDS             complement(5937..7223)
                     /locus_tag="VYO88_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1718591.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKLTRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7374..8111)
                     /gene="mecA"
                     /locus_tag="VYO88_000431"
     CDS             complement(7374..8111)
                     /gene="mecA"
                     /locus_tag="VYO88_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1718592.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8311..9345)
                     /locus_tag="VYO88_000432"
     CDS             complement(8311..9345)
                     /locus_tag="VYO88_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1718593.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9374..10807)
                     /locus_tag="VYO88_000433"
     CDS             complement(9374..10807)
                     /locus_tag="VYO88_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1718594.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(10823..11809)
                     /locus_tag="VYO88_000434"
     CDS             complement(10823..11809)
                     /locus_tag="VYO88_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1718595.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNSIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11811..12914)
                     /locus_tag="VYO88_000435"
     CDS             complement(11811..12914)
                     /locus_tag="VYO88_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1718596.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12904..13749)
                     /locus_tag="VYO88_000436"
     CDS             complement(12904..13749)
                     /locus_tag="VYO88_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1718597.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTKMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDVVIADMDKSYTEYK
                     GEYGG"
     gene            complement(14028..15302)
                     /gene="psr"
                     /locus_tag="VYO88_000437"
     CDS             complement(14028..15302)
                     /gene="psr"
                     /locus_tag="VYO88_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1718598.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15299..16147)
                     /gene="pheA"
                     /locus_tag="VYO88_000438"
     CDS             complement(15299..16147)
                     /gene="pheA"
                     /locus_tag="VYO88_000438"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1718599.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSIHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(16144..16620)
                     /locus_tag="VYO88_000439"
     CDS             complement(16144..16620)
                     /locus_tag="VYO88_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1718600.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16613..17896)
                     /gene="aroA"
                     /locus_tag="VYO88_000440"
     CDS             complement(16613..17896)
                     /gene="aroA"
                     /locus_tag="VYO88_000440"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1718601.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17988..18326)
                     /locus_tag="VYO88_000441"
     CDS             complement(17988..18326)
                     /locus_tag="VYO88_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1718602.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18337..19440)
                     /locus_tag="VYO88_000442"
     CDS             complement(18337..19440)
                     /locus_tag="VYO88_000442"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1718603.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19450..20616)
                     /gene="aroC"
                     /locus_tag="VYO88_000443"
     CDS             complement(19450..20616)
                     /gene="aroC"
                     /locus_tag="VYO88_000443"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1718604.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20626..21693)
                     /locus_tag="VYO88_000444"
     CDS             complement(20626..21693)
                     /locus_tag="VYO88_000444"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1718605.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(21712..22566)
                     /locus_tag="VYO88_000445"
     CDS             complement(21712..22566)
                     /locus_tag="VYO88_000445"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1718606.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(22556..23233)
                     /locus_tag="VYO88_000446"
     CDS             complement(22556..23233)
                     /locus_tag="VYO88_000446"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1718607.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23230..24393)
                     /locus_tag="VYO88_000447"
     CDS             complement(23230..24393)
                     /locus_tag="VYO88_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1718608.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDREVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVTFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(25078..26712)
                     /locus_tag="VYO88_000448"
     CDS             complement(25078..26712)
                     /locus_tag="VYO88_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718609.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEIPIYFSSMIAILLVIAFSTSLTAFYNVFYESK
                     DLISYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEDKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPILTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(26693..27442)
                     /locus_tag="VYO88_000449"
     CDS             complement(26693..27442)
                     /locus_tag="VYO88_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718610.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            27621..29075
                     /locus_tag="VYO88_000450"
     CDS             27621..29075
                     /locus_tag="VYO88_000450"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1718611.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKTQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVERTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYNW
                     ADWFMETTDVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(29165..31783)
                     /gene="alaS"
                     /locus_tag="VYO88_000451"
     CDS             complement(29165..31783)
                     /gene="alaS"
                     /locus_tag="VYO88_000451"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1718612.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     KYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEADMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31805..32290)
                     /locus_tag="VYO88_000452"
     CDS             complement(31805..32290)
                     /locus_tag="VYO88_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1718613.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPHFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32565..32804)
                     /locus_tag="VYO88_000453"
     CDS             complement(32565..32804)
                     /locus_tag="VYO88_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718614.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(33065..34135)
                     /locus_tag="VYO88_000454"
     CDS             complement(33065..34135)
                     /locus_tag="VYO88_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1718615.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIIYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(34132..34905)
                     /locus_tag="VYO88_000455"
     CDS             complement(34132..34905)
                     /locus_tag="VYO88_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1718616.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGNDMNSFIGFSLSH
                     FKTMFGDGRLMLIVTQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34902..35708)
                     /locus_tag="VYO88_000456"
     CDS             complement(34902..35708)
                     /locus_tag="VYO88_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1718617.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35689..36846)
                     /locus_tag="VYO88_000457"
     CDS             complement(35689..36846)
                     /locus_tag="VYO88_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718618.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36905..37855)
                     /gene="murB"
                     /locus_tag="VYO88_000458"
     CDS             complement(36905..37855)
                     /gene="murB"
                     /locus_tag="VYO88_000458"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1718619.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(37967..38719)
                     /locus_tag="VYO88_000459"
     CDS             complement(37967..38719)
                     /locus_tag="VYO88_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1718620.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAPYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38729..39460)
                     /gene="budA"
                     /locus_tag="VYO88_000460"
     CDS             complement(38729..39460)
                     /gene="budA"
                     /locus_tag="VYO88_000460"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1718621.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGGFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39602..40873
                     /locus_tag="VYO88_000461"
     CDS             39602..40873
                     /locus_tag="VYO88_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1718622.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLKELERHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40893..41708)
                     /locus_tag="VYO88_000462"
     CDS             complement(40893..41708)
                     /locus_tag="VYO88_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1718623.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(41865..42518)
                     /gene="phoU"
                     /locus_tag="VYO88_000463"
     CDS             complement(41865..42518)
                     /gene="phoU"
                     /locus_tag="VYO88_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1718624.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42530..43288)
                     /gene="pstB"
                     /locus_tag="VYO88_000464"
     CDS             complement(42530..43288)
                     /gene="pstB"
                     /locus_tag="VYO88_000464"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1718625.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43301..44104)
                     /gene="pstB"
                     /locus_tag="VYO88_000465"
     CDS             complement(43301..44104)
                     /gene="pstB"
                     /locus_tag="VYO88_000465"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1718626.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(44115..44999)
                     /gene="pstA"
                     /locus_tag="VYO88_000466"
     CDS             complement(44115..44999)
                     /gene="pstA"
                     /locus_tag="VYO88_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1718627.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44989..45906)
                     /gene="pstC"
                     /locus_tag="VYO88_000467"
     CDS             complement(44989..45906)
                     /gene="pstC"
                     /locus_tag="VYO88_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1718628.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45906..46784)
                     /gene="pstS"
                     /locus_tag="VYO88_000468"
     CDS             complement(45906..46784)
                     /gene="pstS"
                     /locus_tag="VYO88_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1718629.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47358..48662)
                     /locus_tag="VYO88_000469"
     CDS             complement(47358..48662)
                     /locus_tag="VYO88_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1718630.1"
                     /translation="MQFPEGFVEKYEEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESANRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLFPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48663..49436)
                     /locus_tag="VYO88_000470"
     CDS             complement(48663..49436)
                     /locus_tag="VYO88_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1718631.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCRNDKPLAPFQAKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYVTYLQPWDYAAASILGESLGY
                     RVVTLSGEAPDFQTRQPVMMLPLEMQEEIQSYIYERKRT"
     gene            complement(49426..49704)
                     /locus_tag="VYO88_000471"
     CDS             complement(49426..49704)
                     /locus_tag="VYO88_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1718632.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(49704..50105)
                     /locus_tag="VYO88_000472"
     CDS             complement(49704..50105)
                     /locus_tag="VYO88_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1718633.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50315..50932)
                     /locus_tag="VYO88_000473"
     CDS             complement(50315..50932)
                     /locus_tag="VYO88_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1718634.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50922..51695)
                     /locus_tag="VYO88_000474"
     CDS             complement(50922..51695)
                     /locus_tag="VYO88_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1718635.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     DIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51706..52443)
                     /locus_tag="VYO88_000475"
     CDS             complement(51706..52443)
                     /locus_tag="VYO88_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1718636.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIALGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52448..53578)
                     /locus_tag="VYO88_000476"
     CDS             complement(52448..53578)
                     /locus_tag="VYO88_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1718637.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53662..54051)
                     /locus_tag="VYO88_000477"
     CDS             complement(53662..54051)
                     /locus_tag="VYO88_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1718638.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQIESGEITVDSILAQVKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(54067..54450)
                     /locus_tag="VYO88_000478"
     CDS             complement(54067..54450)
                     /locus_tag="VYO88_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1718639.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54451..55239)
                     /locus_tag="VYO88_000479"
     CDS             complement(54451..55239)
                     /locus_tag="VYO88_000479"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1718640.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55232..56167)
                     /locus_tag="VYO88_000480"
     CDS             complement(55232..56167)
                     /locus_tag="VYO88_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1718641.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56297..56473)
                     /locus_tag="VYO88_000481"
     CDS             complement(56297..56473)
                     /locus_tag="VYO88_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1718642.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56613..57320)
                     /locus_tag="VYO88_000482"
     CDS             complement(56613..57320)
                     /locus_tag="VYO88_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1718643.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57472..58500
                     /gene="queA"
                     /locus_tag="VYO88_000483"
     CDS             57472..58500
                     /gene="queA"
                     /locus_tag="VYO88_000483"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1718644.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLESGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(59161..59550)
                     /locus_tag="VYO88_000484"
     CDS             complement(59161..59550)
                     /locus_tag="VYO88_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1718645.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(59604..60296)
                     /locus_tag="VYO88_000485"
     CDS             complement(59604..60296)
                     /locus_tag="VYO88_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1718646.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKDSQTRVVKKRTKPQVLVQEIPIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSML"
BASE COUNT        17979 a        13774 c        11400 g        17483 t
ORIGIN      
        1 ttatctacaa cctcaaagca gtgttttgag ctgacttcgt cagtcttatc tacaacctca
       61 aagctgtgct ttgagctgac ttcgtcagtc ttatctacaa cctcaaagct gtgctttgag
      121 ctgacttcgt cagtcttatc tacaacctca aagctgtgct ttgagcaacc tacggctagc
      181 ttcctagttt gctctttgat tttcattgag tattacagta aacaattttt ctagctattg
      241 taacaaaaaa gtcactcgaa ggcaactttt ttcgtccata aactttcaaa agagaatggc
      301 ttattcagaa ctaaaagccg cagctttttg catttggtaa tacttaccct ttctatccat
      361 gagttcttga tggttaccat attcagcaat atcaccatct actaagacaa gaattaaatc
      421 cgcatcctga atggttgaca aacggtgagc aatgatgaag cttgtgcggc ccttcatgag
      481 ttttgcaaag gcatcctgta ccagcacttc tgtccgtgta tcaatggaag aagttgcctc
      541 gtctaagata agaatctttg gaatagccag aaagactcgg gctatggtca agagctgagc
      601 ttggccgaca gagagagatt ctccagcatt ttccaacttg gtatcgtatc cctgtggcaa
      661 ctgttggatg aaaaagtctg cattagctgc tttggcagca gcaattactt gctctcgact
      721 ggcttcagga ttgccaaagg caatattatc atgaatggtc ccttgtgtga gccaggtttc
      781 ttgaagcacc ataccaaact gctgtctcaa tgatactcgt gtataatcat aaatggattg
      841 cccatccagc aagatatctc ccgagctaat gggataaaaa cgcataagga gattgataag
      901 agttgatttt ccagcacctg tcggaccaac gatggctatc ttactaccag ctggaatatc
      961 gatagacaag tccttaatca aaattttttc aggatggtag ccaaaagaga catgtttaaa
     1021 ggaaatagct cccttaactt ggtcactggt caagacttcc ttacctgttt cagccacttc
     1081 agggctatct aagactccat agatacgctc tacgcaagcc agagcacttt gcaactcagc
     1141 tagcactgaa gaaatatcat taaagggctt ggtgtattgc tgaacatagt tcaaaaaagt
     1201 cactaaacga ccgacggtca aggttgaacc catcatgata cgataagctc ctactccagc
     1261 taaaagggca taaatgagtg catttacaaa gcgagtcgaa ggattgaccg ttgaagaata
     1321 aaagatggct gactgagaat agcctgagta gttgtcatga gcctcacgca atctttggat
     1381 aaattctgtt tgagcattga aggactggat tatagtctgc tggctaagcg attcttcaat
     1441 caactgagtc tgaattcccc tcgtctctgt ttgcttctgg aagagatgat aggatctctt
     1501 ggcaataaag cgtgaaatca ccatggacag tggcgtcaac agcaagacta agagagtcat
     1561 gaggagatga atttggagca tggctagaat actaaccaaa atcatcaaaa caccaatgaa
     1621 aaattggtta aaaatcatgg tcaagccagc tgccaactgt tcgatgtcca tggttacacg
     1681 actaaccatc tctccactac cttgcctatc tacaaaggca atcggtaaac gatggagctt
     1741 atggatgatt cgctcccgta aatctctggt ataagagaag attagacgat tatagaggag
     1801 aggattggcc cattgtacca gagtatttcc tattaccacc aagagcatct ggagaaaaat
     1861 ctgccaaaaa actggtgatg aaccagccac taggacttgg tcaatgacct gcccaatcag
     1921 aataggtagg taaattgata agccaacttg ggcaatagtt cctagaaagg ctaggaaaag
     1981 gaggaaggga tggtttgcta aatctacggc taaacgtttg agcgtctggt ttacagtttg
     2041 tcgtttcatt ctagtcctcc tttccatgtt gggatgcatt gatttcacga tagacttggc
     2101 tggatttcat caagtcatcg tgcttgccaa cagctagcaa ctcacctttt tccaagagga
     2161 gaatctggtc cgccatctgt aaagttgagg ttcgttgaga gatcaaaatt aagctcgtgt
     2221 ttggaaaatt ttctctaata gctttcaaga gcttggactc tgtaatggta tccagtgccg
     2281 aggttgcatc atctaggatg agaaacggag cttggcgcaa gactgctcgg gcgatagaca
     2341 acctttgttt ttgtccacct gagaaatttc gcccccctgc ctcaactagg acatccaaga
     2401 gtccttcctt ttcactgaca aaatccttag cttgcgcaat ctccaaggcc tgccagagtt
     2461 tctggtcaga tacttcttga ttgaaaccta gagtcaagtt ggaacgaatg gttcctttaa
     2521 agagttcgac cttttgaggt acataggcaa tccaagaccg ccactgctcc aaattaagag
     2581 gactacgtcc attttgataa aggtcaatgt tccccttgtc tactggataa agtccaagta
     2641 agagttgcac caagcttgat ttaccagaac cagtcccccc aatgatacca aggatttgtc
     2701 cttgagtcat atcaaaggaa atgtctctca gagaaggctg ggccgcatca ggataggtaa
     2761 aggtcaattc ttggacttgt aaaaccttat ctctggtagc ttgcttttgt tctaactctg
     2821 aatggatatc ctctggagcc tcaacaaaga cttcctcgat tcgcttggct gagatatagg
     2881 actggttgag agaatttatc aacatggcta gcttgaccaa ttccaccaaa atctgtaaga
     2941 ggtaattgat aagagcaatg agagcacctt gactgagcac tcctccttga attgaaatat
     3001 agccttgcca gataataacg agaagagttc cattgacaat cagataggtc agaggtgtta
     3061 ataaactaga ccagaaacct gtcttttctt gtaatctagc ataaacttgg ttaagggttt
     3121 gaaaaatctg taactctcgt ttttcttgac caaaagcacg aataacccgc atcccttgca
     3181 attgctggcg cgtttcctga accagttggt ccgttttctt tctgagacta ctgtagagag
     3241 gattgaccaa tcgagatacc cctacaatga caatggtcaa aatggcaacc atgactaaga
     3301 accagaaagt caactcagtt gagattcgat aagccataaa aatggcacca aaaacgataa
     3361 tgggcgctcg caaaaagaga cgcaggaatt gattgatacc agtctgaatc tggtaggtat
     3421 ccgaagtcaa gcgagtgacc aaactagatg ttgtcagacg gtctctgctg tccttgggca
     3481 aggaaagaat atgacgataa agatcgtttg tcaattcctt agcaaaacct actgctgcct
     3541 ttgctgagta aaattgagct atcaaggcca ctaaaacgcc aattactgca aagataagga
     3601 gcaggccaat ctgcatccag agatgacctt gatctccctg aggtaaagat tggtcaacaa
     3661 tcccagcaat caccattgga agcaagagct caaaaacagc ttctaacagc ttgaacaagg
     3721 gggctaaaat tgattccttg atgtagggtt tgaagtaaga taataggtgt ttcataaatc
     3781 ccttctattc atattctaga aatgaagaaa gtgggaagcc ccactctctg ttttatttgt
     3841 ttaagtaagg caatagatag ccatatcctg ctttttccat ctcatccttg gccacaaagc
     3901 gtaaagaagc agaattgata cagtaacgga ggccgcctaa ctcccgcggt ccatctgtga
     3961 aaacatgacc caagtgagca ctgcctgaac gagaacgaac ttcaattcgc tccattccat
     4021 ggctcagatc cttgtaataa tgaatcaact ctttggaaat cggacggcta aaacttggcc
     4081 aaccacaacc tgaagcaaac ttatccttgg caaaaaagag tggctcacct gtcgtaatat
     4141 ctacataaat cccctcttca aaggtttggt cataggcatt ggtaaatgga gcttctgtag
     4201 cagcttcttg tgtgacacga taagactctt cagatagact ggccttcaac acctcttgac
     4261 taggcttttc atagtttgct gcatcaatca atggcttatc agcatcggtc acatcgatat
     4321 gacagtaacc tgaaggattc ttcctgagat aatcttggtg gtagtcttca gccagaatgt
     4381 agtggcgtaa ttgctccact tctactgcaa tctttcgacc cagcatgcgt tcctgctcct
     4441 gtaccactgt gtagatagct ggcaaatctg cttcatcctg ataataaatc ccagttcgat
     4501 attggcgacc acggtcattc ccttgttgat tgatagatag aggatcgata actcggaaat
     4561 aataaagtaa aatctctctg agtgacactt ccttctcatc gtaaatcact tggaccgttt
     4621 ctgcatggtc tgtttccttg atcaactggt aattggtcgt ttcgacttga ccattagcgt
     4681 agccaacact ggtttctagc actccagaaa tgcgtgaaaa atattcctct aggccccaaa
     4741 aacaaccacc tgctagataa atttctgcca tttttatttc tcctttatca cgtttttaac
     4801 taatactctt cgaaaatctc ttcaaaccac gtcagcgtca ccttaccgta tatatgttac
     4861 tgacttcgtc agttctatct gcaacctcaa aacagtgtct tgagctgacg tcgtcagttc
     4921 tatccacaac ctcaaaacac tgttttgagc agcctgcggc tagcttccta gtttgctctt
     4981 tgattttcat tgagtataaa cttcttttca caaaaaggat atgaacccct ctggtcaaga
     5041 gtttccccat cctatattct attctttatt ttgcttctac acggacacct tgggtatcaa
     5101 ctctcaagtc atgcagtttt cctttgaaag gttgcttttc caattctgcc ttaattgttg
     5161 gcatcttgtc atgagaagcc agaaccataa ctgtcggccc agcaccagaa aggtaggttg
     5221 cataggcccc attttctttg gtcacttgct taatcatcgc aaattctctt accaagtcct
     5281 gacgatagcg ctcatggaag aggtctccct cgattgcttg cccagcggtc accatgtctc
     5341 ctgccaacaa ggcagcaacc gctacattgg cgatagaact tgcagcaaca gcttccttat
     5401 aagacaattt tttaggcaag acactacggc tgtcgcgagt acgtaattca tagtttggaa
     5461 tgtaagctag aaaatcacac tctggaaagt ctgctacgat agcagagact tgcccttcaa
     5521 cagaacttgc aataacgaga ttaccataaa tggctggagc cacattgtca ggatgccctt
     5581 caatcttggt cgctaactgc aatttttcat ggtctgataa gttgagttga cccagttggt
     5641 tggctagttc aatcccagca acgataaccg agctggaaga acccaaaccg cgcgccaaag
     5701 ggacatcact ggtcattttc aagcgtcttg gttgcaagtc tggtacaatt tgcaaagcga
     5761 ttttgagcaa gagattacgc tcatcatgtg gaatccattt gccaatctgg tgttcaatca
     5821 gccactcatc tcgttcttcg cagacctcaa tttgaagata cttggttaca gctacaccga
     5881 ccgagtcaaa acctggcccg atattggcac tggttgcagg tacaataatc ttcatcttat
     5941 tctcctagca ccttgaaggt attcaagagg tcgaattctg aaaccttctt caattcagct
     6001 gagacatttt caagctgggc tttattaatc ttgtgtgtga tgataacgac acgcgccttg
     6061 tcaccctctt tgccatcttg aaggatttgc ttaaaggaaa tatcttgagc attgaagatt
     6121 tcagccaact tcaagacctg accttttgag tctggagcca agattgagaa atagtagttt
     6181 gctttgacat cttcaggatt tgccaagacc aagtcacggc tatattcgtt gaagtctttg
     6241 ccaatggtac catcattcaa acgacgaacg atacggacaa tatcagctac aacacttgtt
     6301 gcagttggtt tttgacccgc acctggtccg tagtacatag actcaccaat accgatagat
     6361 tctacaaaga cagcgttcat tacgccattc acactagcaa gtgggtgcgc tttaggtagg
     6421 aaggttggag tcacttctgc agcaatacct gaagaagttt cctcaataga accaaccaat
     6481 ttcactacgt aaccaagctc ttgagctaca gctacgtctt ctggtgtgat attgcggatt
     6541 cccttgtggg ctacatcatc aaaggcaatc ttcatgccaa aggcaaattg gctcaaaata
     6601 accatcttgt aggctgcatc aatcccatct acgtcattcg tcggatcgct ttctgcaaat
     6661 cctagacgtt gtgcttccgc aagagcatca tcgtaagacc agccttcttc caccatcttg
     6721 gtcaccatga agttggaagt tccgttgact actccaagca cgcgcgtaag tttatcagaa
     6781 gccaaggaat ttgctaaagt acgaagaatt ggaatcccac cagcaactgc tgcttcgtag
     6841 taaagtgcta ccttgttagc ttgagcgatt tctagcaatt ctgcgccatg gacagctaaa
     6901 aggtccttgt tagcagtaac aacgtgtttt ccagcttcca aggcacgagt gataaaggtt
     6961 ttagcaggct caatacgccc catcaattcc actacgatag taatatcctg gtctgataaa
     7021 atatcatcca cattggttac aaagttaaag tcattccctg ctgcaagcaa gcgatttttt
     7081 tcatcttcat ccttgaccaa taccttagca actttgatat ctgaatgtgc tgattgattg
     7141 atttttcctc cattttcctt taggaggaaa ggcacaccac ttgcaacggt accaaatcct
     7201 agtaaagcaa ttttaactgt catctttatc tcctcgaaat tttctaatat agccattata
     7261 acagaatttt gtgaaaattc ctattatagt aaatcactat ttcagtataa aaagaaaaaa
     7321 cgaatcagac gattcgctct tcttaaaatc tgaaaatagc tttccagaaa ggattagccg
     7381 attttttgca gattgagcac tgcatcgtga ctcatcaaga cttgaccata ctcttgtaag
     7441 actgagcgac tgatatcact atcgtctgca aactcgcgca tacgggccaa cagccaagct
     7501 ggatatgggc ttggatgatt ttcaatatcc actaaaatgg tcaaataata gcgctcgttc
     7561 attttgtaga gttcagaagt ttccatttca aaagtcactg tcttggcaaa agctaccaag
     7621 tcagccaact tagcaaaaga aaggatgtag tagatgtaag gttctttctt actctcagct
     7681 tcttgttcag cctgctcttg ctcttcttcc ttggcttcaa cttgctcaag agattgaatg
     7741 gcttcgatat catccttggt tttgtctgcg atgctttttt ccagggtttt gataaattca
     7801 tctggagaca tttgagccaa ttcttccata tctggcaaat ccgataagtc ttcaaaatct
     7861 agattttggt caatctttga cttggtcaca aagacatcta ccttatcagg ttttggagtc
     7921 acacggaagc tcaacatgcc tgtatccaga aagctatcag gcatctctag ctcatccaag
     7981 atagcataaa agaactcttc tgttttttct tgaggaacga gaaagtcagc aatctccatt
     8041 ccacgatcca tcaaatcctc taaagacatc gtgattttta aagttgtatc actaatttgt
     8101 ttcattttca ttgctagtaa cctcatactt tcagttctat ctattatact agatttttac
     8161 gattttatca aaagaaggct cctctatacg gatagatttt ccctaggatc tttctatagg
     8221 agactccaag agaaaatttc tgcagacaga tagaaaaagc cttcaaaatc ggctaagagc
     8281 cgattttgaa gaccttatac atcagaatac ttataattta aaggttgcta caccgaggat
     8341 agaacgattt aagtttctga gaatttgaag actttgctca aatttcttat aacgagtcac
     8401 tccgtactct tcaacaagaa ggactgtatc tctttccaaa agagatgata catcctgcaa
     8461 atctacaaaa tgcattcctt ttaaagcttc ttgactctgt ttcaatttat ctaggatagc
     8521 tttatttgag ctaacgatgg tcaattcctg tccagtattt ttgtatgaca aaacatctgc
     8581 taggttagca attgttgtaa tctctgttac aaaatcaatt tgatactgag aaaaatcacc
     8641 tactctattg attgttggat taaagagata aactaacaca tttcccatca caaccaaaat
     8701 cacacaaacc actccaataa caactaaacg aagaatcaga tttttcacat ttaagccaag
     8761 cgctgtttca ccatttgcgt tcaattcttt agagttgatg gtttccagtt tttcaatttt
     8821 cacatttgca taagcatgtt taaatttctc aatcaaccca tcaatttttt tctctaacaa
     8881 gtcattggca tctttacttg atgtcaaaat tttcacacca acccctgcat cgtcaatcat
     8941 atagtagacg gtcaattttt tccaccaata gtcattcgtt gaatttttca aggttgtttc
     9001 cgtcgtgtct aattcactgg caattttttt caactcactg ggttctacat cattgaaaag
     9061 ataagctcca ttcaaattac catcaatcaa tttcccataa aaatcactat aaccaccaat
     9121 ttgatgattc aaaatcgttt tggccgaatc ttctggagga gtgattttat agataagata
     9181 agttgaataa cttgttgtat ctttgacagt gtttttattc ctaactgctt taattgtaaa
     9241 tggtacagca atgagagcaa ataaagcgat gagagctaaa atatttgctt ttcgtttttt
     9301 ataaagattt gcaaacaaat cagctactga ataatgttca aacatgattt ttttctcctt
     9361 tgtttagtag atactagttt tcctttgtaa gcatttttgc tacaaatata atcacaagaa
     9421 caattcccca gaattgcatt gtaaataaat tgaagaaact ttctgaaaag ctgcttcttg
     9481 gcataaagaa tagattattc aagatgagta gggataaagc aaataggatt gtccttgagc
     9541 gataggctac ttgcagcatg gctataaata atacgccgag taagaaacta agcagaaaga
     9601 ctccaatcat accatagtcg gtatacaact ccatgatata actacttccg ataccatgcc
     9661 ctttcaggta ttccttgttc aagacaagat aggatagatt gtgggcataa ctattactat
     9721 caatagctag ttccacacta ttggttgtat gttcaaaggc ttttcctccg aaaatggctc
     9781 ccaaactccc ccttgcaaaa taatcaagaa caggaccaaa agtaaaatta cggaaatctc
     9841 ggtaagggag gctactgtta aatagaaaac ctcgagccag aacaccaaaa ctagtccctt
     9901 gtttatagat aaagtcaagt aagatatccc agaaacctgt atgggaaact tggacattat
     9961 cccgtacata attgagtact cccatcgcta acatgagaat aggagaacct acaaaaatcg
    10021 ctaacttttc tttaaaccca atccattttc ctttttcagc ttgctcccgc ataaagtaat
    10081 aaacaaaagc aaataaaata cttaaaataa agggatttcg tgtcccaatt gccaaatgaa
    10141 tagtgttagc tgcaataaag gagacaagca ctgctgtggc ctgcaatttc tttggcttgg
    10201 ttgccagata catacacatt gcatagaccg taaaggtaga caaaatgtag gtaaaataag
    10261 gcagtttact ttcaaaattt gcatagtagg catagtagga agtctgcaaa cgatacaaga
    10321 gccgttcaaa taaccgaatg aaatagaaag gataagttag aagaaaaact cctagtgata
    10381 caaagcgtaa ccgcttgata taaacctctt ttagagaatt tcctatattt gctactttta
    10441 ttttcttcct agctatgaag taacgagcca ggacgcctcc tgttgtcaag cccagaatcg
    10501 aaaccatgac aactataaag gcaaaacgat aggctattgg atgataggta tccaaagcac
    10561 catccctaaa ataatcaatg gtcggtcttg ataccagaaa tacaaaaatg gttaaataga
    10621 aaataaaatg gattaagtaa tacttgatat cattccaaca agcaatcaag ctactaacca
    10681 acaagaacaa taaagtagaa agtaagctaa cattattatt attaaacaga tacacaattc
    10741 cacttactag cgtcaaggca taactgacta tggtcaaact aaataataat cgtttcccat
    10801 caatcacttg gtcacccccg ttctaatgta attttttaga tttttcaata tttttcagta
    10861 ataagaatcg gtataaggaa atatttatga atagggccaa agcactaatt cttctcccct
    10921 tacggaaaat tgaattccta gaaatagcaa aggcatggcc ttttaaaaaa cgatgaatct
    10981 gagaataggc ttcaaactgt ttatactgat catctagcaa catcttatcc agaataaaga
    11041 agtgggcata ggccaatctg aaaaaagcga cctctttcaa gtcaggatag tttttcacaa
    11101 cttcattata aaacttttgg tagatatcaa tataggctaa atccttctct gcatagggtt
    11161 tggtcgtaat actatcccct ctatggaaat agtaataata gggtttagta ttaaccacat
    11221 acttcttggc caacttgatt aaatcaaaat ggtaataggc atcttcgtaa atcaacccct
    11281 taggaaagga taggtcagtt gcaatctgtc tcttgattag cttattgcaa atcgtcccag
    11341 gtattttttc acctatgagg tattccttta gaaatgtttg agaatcacag acaaaatagt
    11401 catcctgatt ggctgactgt gggctttcat cattagcata gacattcatg acaccacagc
    11461 tcgaaacatc cgcatcttct tgaactaatt gctcatataa gctctgaatc atttctggat
    11521 ggatataatc atctgagtca ataaaaatca gataatcccc gtgagcctgc ttcatcccat
    11581 catttcgtgc ttgcgacaat ccttcgttct ttttatgaag cactgacacc ctgtcatctt
    11641 gttcagcgat tgaatcacac aagcgaccac tttcatctgt tgcaccatca tcaacaagaa
    11701 taatttccag attttgatag gtctgcttct gaatggaagc tatcgatttt tctaggtact
    11761 gcgccacatt atagactggc acaatcacac taattaatgc agtttccatg ctactcctct
    11821 aatagttttt ctacttgttc gatttgtttt gtaattgtaa attgttgaat gaattggcta
    11881 gcctcatcga catcaaagtt tgaggcagaa gtcatgtaat tagtaatcgc ctgagctgcc
    11941 tcttgattgc tctcaatgat ttgtccaaat cgtccttctt gggataattc ctcagcccct
    12001 ccaacgtccg tagagataaa agggagtccc agactcaagg cctccacata cactccagga
    12061 aaaccttctt gtttagacat agacaaaaga actttcgtct gagatagata ctgataagga
    12121 tttttttgat aaccaaggaa atgtacatag tcctcaatcc catactcttt gactcgtttt
    12181 ttcagttcct cttccatatc accagccccg ataaaataga gatgatagtt ttttccctct
    12241 tggtgtaata atcgtatcac ttccactaca cggtcagaac ccttattttc ctcaatccgt
    12301 ccgatagtac agatactttg aggagcaatc tcgatatcga tcttctcttg agatttttct
    12361 agaatagtct gaaaatcata tccattgtag attgtctgta atttagaagc ataatctgga
    12421 taaacttcct tgatagaatt gctggtcttt tttgaaatcc ctacaattgt attcgcagca
    12481 tccaactggc ttctatgtga ttctctttta gagctatcct taagaagttc ttcaatactt
    12541 ccatgaatcc aagatatctt cttgacttct cttcttttag agaacaacag tggtggattc
    12601 ataatggtaa aagaaacttc aacatcataa tcatctttta caagcaaacg acgagccagt
    12661 cttggaaaat aaattctcat tctccacaaa aaagctcgta accatctggt ttggcgataa
    12721 tcttgaaggg attttaaaat gcgtacatgc tttggaacag attcatatcc cttgtcaaag
    12781 tgctccattt caagaatatc aatatcatac ttttctggat ccagatttga aacaatggtt
    12841 gatagaatct tctctgcacc acctccaaga gaaaaagacc acataaaaaa taagattttt
    12901 ttcttagcca ccatattctc ccttgtattc tgtataagac ttatccatat cagcgatgac
    12961 aacatcatga tgcggtacct gcttgtctgc tggtggaggc gtcatataat ccccaaaagc
    13021 agttctgaga tagacatcat agccgattgg aataggcatc tttgttcctt caaatggcaa
    13081 gaaaagattg tcttcaaaag atgtgattgg gtacttgttt ctcatgtagc caggacctga
    13141 gcataattct gtaatgccat cacaatcagc caaatcatac ttagtcattt ctttctcagc
    13201 ttttttccag atgcgataac ggagagattt tggagtcaaa cccagtaaaa tgcgacttcc
    13261 ccatttcatg agagcaccat gcttttctgg aatagtttgc gcacaaaaga gtgaataaat
    13321 caaggcccaa cgaacctgtt ttttccgctc agctggatct ttcggataat aatccaaagg
    13381 caaaacatcc aaggccagac catgtggcaa atccaaatcc tgctgataag gcttgataca
    13441 ggtggtttcc ttgtcacgaa tggtaataaa aagattacga tcaacaaaat ccttgtaact
    13501 ctttgacaag aaataacgtt catctgcata acgaggccat aattctgcta atttctcata
    13561 atctttacga ggcataaaaa agtctaggtc gtcgtcccaa ggaatgaacc ccttgtttcg
    13621 aagggcacca atagcgcctc ccccacagag atagcaaagt aaatcatgtt ccttgcaaaa
    13681 ggccacaaaa tattcagcca tctccagact acgagcctga attgctttta aatcagtcat
    13741 attgttcatt attctttcta tcgtatcgtt tcattatacc acaaacaagg ggtgaaaatc
    13801 tattgcagac tgtaaaaaat caaagcctga ctgctatcca aatagctatc aaactttgat
    13861 ttttctgtct tatactcttc gaaaatctct tcaaaccacg tcagcttcac cttgccgtag
    13921 gtataggtaa ctgacttcgt cagtcttatc tacaacctca aaactgtgtt tttagcagcc
    13981 tgcggctagc ttcctagttt gcactttgat tttcattgag tattatctta tctcaagccc
    14041 atttgagcga gcttggtttg atatttgttt tgatcaacca gcaagcccaa gcctccataa
    14101 acatcatagg catctaccca gtcacccagt tctggaatcg tcaatttttc aataccattt
    14161 tttgctccat ccaaaacaga taaaccgttt gttaggagga aagtataagg tacgttggtt
    14221 gaggtcatag caaaaacctt tccaagagct tcagaaccag tgaaaagttt agtgggatct
    14281 ttaatttgct ctaaaattgc tgttaaaact tgttgctgtc tttttgtacg gccgtaatcc
    14341 gcctcatcat catcacggaa acgagcataa ttgagcaggg tcgagccatt catctgctgt
    14401 tttccgactt taatggtttg ggttggagac tcagtctcgg tagcatataa atcatctccg
    14461 actgtagctt ctgttagggg acgcccattc aatgttgaaa attgagcatc aatcgtcacc
    14521 ccatcaggga aaagcgtgtc aatcgctgtg gcaaaggcct ggaaatcaac caaagcgtag
    14581 tacttaatgt ccaagtcaaa attatctttc aagacttgac gaaccatttc tgcccctttt
    14641 tgcccctctt gttctcctaa ctcgtaggct acgtttaact tgttatctgt ctgttttcta
    14701 ccgttaatca cttgactata accatctata tagaccaaat tatcacgcat gaaactgact
    14761 agcttcattt tcttatctga gcccccgaca tttaatacca taatagagtc agttcgtgtc
    14821 tcaacactgt tctggccgat tcgaccatca gtacccatga ttaaaatatt aactccatct
    14881 ctagtgtcct gaccattaaa gacttctact tgagctgccc gggcatcagc agttttcttt
    14941 gcgctagcat cttggtaacc acgcaaaaac atgaatacca tggccaaagc cacacagacc
    15001 aaaagtgaaa aaatcaccat aaaaattcgt ttaagacgga gcttccgtct tttctttttt
    15061 ggagggaaag agagtgcttg tgatttggat tgtgagcgac tccggttcgc atagcttggt
    15121 aagtcaacct gctcttctct ttcttgttcc aagctagagc tactatttcc cctagcaaga
    15181 gttagctttt cttgcaaata ggcaaactca tttttttctc tctcattgag gtagtgaata
    15241 ttttttagca aataatcata acgcaactgc tcatgatgac ttaagggatt ttctttactc
    15301 atcttctctc ctttccatgg tctgatattg gataaatagg ataggcaccc agaattttat
    15361 actggattcc aatcgcttct aattcttttt gggcaaagtg gaccaagtcc ttatcggtat
    15421 aatccacatc gataatgaaa aagtattcac ccagtgctgt cttgagtgga cgactttcaa
    15481 tttttgtcaa gtcaattcct cgccaagcaa aggtcgacag ggccttataa agtgcacctg
    15541 gaaggttgtc aggtaatgtc aaggccaaac tcatcttttc agtttgtgct tgcaagggaa
    15601 tactaggctt ttcagctcct agaagccaga aacgtgtgaa attggcttcc atttcctgaa
    15661 tatcctcggc aatcagttcc aatccatatt cttcagcaga acttctaggt gcaactgctg
    15721 caaagggctg atctggatgt tcggaaataa aacgggccgc ataagctgta ctagctgtta
    15781 cctcgatttg agcctctgga tattgttcat cgatgaattt ctttccttga gccaaggcct
    15841 gtggatgtga aaaaatcttt tcaatcttag tatggcctgg aaccaccatc aactgctgat
    15901 gaataggctg aacgatttct gctactgctt ggatgtgagc ctgatgaaaa agatagtcca
    15961 aggtttcatg aatactaccc tcaatagaat tttcaactgg caccacagaa tagtccacta
    16021 atccttgctc ataagccttg atgacatctg taatgttggc aaaagcctgc aattcctcat
    16081 gaggaaaagc tgtctgcaca acgtggtgtg aaaatgatcc cttgggacct agataagcaa
    16141 ttttcatctt agttcctcta taatttcctc tgggcttagc ttggtcacat ccaaaacccg
    16201 actagccact tcctcatacc aagcctgtct ttcttgaaaa atagctacta gttcttcctt
    16261 gctattattt agaaaaagcg gtcgctgatt gtccttatca gctacgatac gtaggtagag
    16321 ggtttcaaaa tctgctttca ggtagatgtt atctgtatta gtcttgagta agtcacgatt
    16381 tctctgagaa ataaccactc ctcctccagt tgacacgact tggtctgttt gtagtaaatc
    16441 agctaggact tctgattcta cctgacgaaa ggctgcttct cccttttcag cgaaaaaatt
    16501 cgcaatggac atacctaggc gcttctcaat cagagcatcc atatcaaggt aattagggtc
    16561 caagcctctt gcaatagtcg attttccagc ccccataaac cctaataaca ccttagccat
    16621 gaatcaagct ctccaaatca tcaaagaaac taggatagct ggtattgatg gcttctgcac
    16681 ggtcaagctc cacctctcca tctgcaacca atagggctgc gatagctgtc atcatgccga
    16741 tacggtggtc accaaacgta ttgactctag caccgtgaag agctgatttt cctttgataa
    16801 tcatcccatc tgccgtagga gtaatatctg ctcccatact atttaaggcg tctgccacaa
    16861 cctgaatacg gtctgtttcc ttgaccttga gctcctcagc atccttgata actgttacac
    16921 cttgggcttg agtcgcaagc agggcaataa tgggcaattc atcaatcaat cgtggaatca
    16981 aagcgccacc aatctctgtt cctttcaagt cagaagactc aacagtcaag gtagaagatt
    17041 tagcgactgg atcgatttca gttatttcca attttccacc catggcacga atgacatcaa
    17101 taataccggt gcgagtttcg ttgatcccca cattctgcag cactagacga gaatttggaa
    17161 caatcaaacc tgcgactaac caaaaggctg cactggaaat atctcctggt acgaccacct
    17221 tctgtcctgt caatttttgt ggcccttgga ctgtgatttt cttaccgtcc acacttaaat
    17281 gaccaccaaa ttgtttcaac atatcttcag tatgattacg ggtgcactct ttttcgataa
    17341 taactgactc ccccttagct tgtaaggctg caaacatcaa ggctgacttg acttgggcag
    17401 aggcaattgg caactcataa tgaataggtc ttaggttttt cgtccctttt aagcgaaggg
    17461 gaggcaagtc tcgttcagtt tgccctgaaa tgctgacgcc catttttttc agtggaaggg
    17521 tcacacggtc cataggacgt ttggaaagac tatcatctcc aaacatctct acttcgaaat
    17581 ctgcaccagc aaggacacct gaaatcaggc gaatcgaggt gccagaattt cccatattaa
    17641 gggcattttg tggcgctttt aagccagcca tgcctacacc ttgaatggta ataaccccat
    17701 ctttatcctc aatttcaaca ccaaggtcac gaaaaacctg catggtcgaa agaacgtctt
    17761 cacctcgcag aatatcataa accttggtct caccctcagc caaacttcca aagataatgg
    17821 aacggtggct gatagacttg tcacctggga cgcggatact accatgtaaa tggcgaatgt
    17881 ttgtttttag tttcatactg gacctcatac ttgcaatact tttacctatt ttatcataaa
    17941 aagccagaaa ttccttaaaa attcctgact ttaggatagt tcttttctta tttcagcaat
    18001 tctgaaactg gttcaaaaac aattttttca atgtcagaaa ggtaaatggc caattgttgt
    18061 tgcttggtaa agaattctga caagaggcta tttccttgaa tctgtttacc aaagccttcc
    18121 atcttagctt ggaaggacgc atctggcatt tgacctgtct gtgctagttt ttgaatttcc
    18181 tcttgaaagg caagatattc tgtaaagatt ttgcttgcct cagcatctgc tgcaatcgca
    18241 tctttagctg ctttaacagc cttgtattct ggtaatccgc gtagaccgcg actgagttcg
    18301 tttgcactat cgtaaatatt tgacatgttc ttctccttat ttgatgacga ctgtatagtc
    18361 ggtattttct gttatgagat gctcagctct ttccaagtct tgagcatttt taaatgaaat
    18421 ttgtaggatt ccgtgaatat cctcacgatt ttcctcgttg atgtggatgt taaccaagga
    18481 agttccacgt agcagttcca aaatccgcag gatgacatct tcttcatcag gaacgtcaac
    18541 atagaggtcg taagagctat ccacaccacc acgcttatgg atttccatgg tctggcgttg
    18601 ttcacgcgct tggttaaaaa agttccaaat ttgctcttca tctcccttac taatggcctg
    18661 accaatcact tccaaacgtt ccttgaaatc ctcaattcta tccagaatgg tctcgctatt
    18721 ggacaagaga atggaggtcc acattcctgg ctcgctttcc gcaattcggg tcatatctcg
    18781 aaaaccacct gccgcaaagc gccttgccat ctcatgctct tgagcataga ccgcagtctg
    18841 ctccatgaga ctagaagcca aaatatgagg aaaatggcta atctgagaag tgacacgatc
    18901 atgctccttg gcatcaatct cgataaaacg agcatgaaga cctgaaagca gatccttcat
    18961 ttccttaagc gtgtcctgac ttgtcaggct tgaaggtgta aagatataat aggcattttc
    19021 aaaaagattg acatctgccg aagcagcccc tgtcttgtga ctaccagcca tgggatgggc
    19081 cccgacaaag cgaacagact tgccagccaa atactgctcc gccgcatcca caatggttga
    19141 cttggtcgaa ccagcatctg aaataataac gccttctcgc aaatccaaat tggccaactc
    19201 cttaatgaaa gcaatagttt gtttgattgg caagctgagg ataatgacat ctgccaaagg
    19261 agcaaaacta gcaaaatcat ccgttgcacg gtcaatcatg ccttctttca aggcgatatc
    19321 tctcgaagct tgactacgat tataacctaa aatttcataa tctggatgat cgcgtttgat
    19381 accaagtgcc atagaggctc caatcaaccc aagacctgcg atatagattg tttttgccat
    19441 aggaactcct taatagttct ttgtatagtc tcggtgtttg gctaccgctt cttttagttc
    19501 ctcaagatta tctgatgaga atttttcgag gatttcttgc gccagaaccg ttgctacaac
    19561 tgcttccatg accattcctg cagctggaag agcagtcgga tcacttctct ccacggttgc
    19621 cttgtaaggt tcgtgggttt cgatatccac actcataaga ggtttataaa gagtaggaat
    19681 gggtttcatg accccacgaa caacgatggg ttgcccatta gtcataccac cttcaaaacc
    19741 acctagatta ttggtacggc gagtataacc gtcttcttta gaccagagaa tttcatccat
    19801 aacttggctg cctttacgat aaccagcctc aaagccaaga ccaaattcca cccctttaaa
    19861 ggcattgata gagacaacag cttgagccaa tcttgcatcc aattttctat cccattggac
    19921 ataggaacca agaccaactg gaacgcctcc gacgactgtc tccacaaccc caccgatggt
    19981 atcaccatca cgtttgattt ggtcaatata gtccttgatt tcctgttctc gttcttggtt
    20041 gacaatagaa acttcagact gggcagctct ttgcttaatt tcagcgactg tcagattttc
    20101 aggaacatcg atttccttgc caccaaagac cacgacatgg ttggcaatct ccatatccag
    20161 ctcagctaag aggcgtttgg ctactgcacc aactgccacc cgcatggtgg tttcacgagc
    20221 tgatgaacgc tccaaagaat ttcgcaaatc atcaaaacgg tacttaatcc ccccaaccaa
    20281 atcggcatga cctgggcgag gatgagtaat tttccgcttg cttttaaggc ggtcttcaat
    20341 gtcctccgca gacatgatgt ccagccattt ctggtggtcc ttattgatga catccatagt
    20401 aataggcgcc cctgtcgtct tcccgtggcg aacgcccgaa gtaaagacaa cctggtcact
    20461 ctcaatcttc atacgaccac cacgaccgta gccaccctga cggcgtctaa ggtcctcatt
    20521 gatatcctca gctgtcaatg gaagtccagc tggaattccc tcaataatag ctgttagacg
    20581 ggggccgtgt gattctcctg cagttaaata tctcatacac tctccttatt ttaccaagta
    20641 gtctttcatc tcttccagag aaactgggtg aatgatcgct gaaccaagct ctggcaccaa
    20701 gaccaatttc aaggtgttac cacgcgcttt cttgtcatga gtaagagcct gataaagctt
    20761 gtcaacttcc caattttcat agtcaacagg caagccgaat ttctgacaca tctctgtgat
    20821 agattgggta atgccagctg gcatgaggcc tttttcctca gcaaccttgg aaatctgtac
    20881 cattcccatg gcaacagcct ctccatgcat gaccttgcca taaccggcag tcgcttcgat
    20941 ggcatggcca atagtgtggc caaaattgag gtaaagacga ataccattgt ccaactcatc
    21001 ttcaaccacc atcttgcgct tcacctgaca agaatgttca atcaaggtct ctgcatgttc
    21061 caaaatactc tcaacagaac cattcagtcc cgtcaagaga gcccacagtt ctggatcctc
    21121 aatcaagcca tacttgataa cttcacccat cccttcaatc aactctcttt ttccgagggt
    21181 ttcaagaaca agtggatcaa tcagaacccc atctggttgg gcaaaggtcc ccaccatatt
    21241 tttagcaaat ggtgtgttaa cgcctgtctt tccaccgata gaagaatcaa cctgagctgt
    21301 caaactagtc ggaatctgaa caaagtgaat accccgcata taggtagagg ctacaaagcc
    21361 agccaggtcc ccaacaacgc caccaccaag agcaacgatt ccatcgctac gagtcagacc
    21421 ttgcttgact agaaattcat agactttctg aacagtagtt aaattctttc tttcttcacc
    21481 ttctaagaaa tcaaaaacag ctacctgaaa accagcatct tctaggctga gcttgacctt
    21541 ctctgcatag agagaggcta catggttatc tgtcacaatg actacctttt gcggttgcca
    21601 gagttctcgc aaccactgac cagcctgggc catacaacct ttttcaatct gaatatcata
    21661 aggatgatga ggaatatcga ttctgatttt cataggagag tctccctttc tttattggta
    21721 tttttctgtt aaagactgcc aaatctcttc tgtcggcatt tccttgcctg tccacagttg
    21781 aaaagcttct gcagcttgat agagcaacat tcccagacca ttgactgctg gattgccctg
    21841 acttctagcc catttcaaaa acggtgtttc aaagggttgg tatatgatat ctgcaactaa
    21901 gagagtttct ggtaagacta tgttttcagg aacaggagag gattggccat ccatgcccac
    21961 actggtggca ttaactagca aatccgactc ggcaatcctt gcttgcagtt cagaaacata
    22021 ttctaaagca cacaaatcca ctttaaagcc tgtctgctcc tgtaacttgt ctaggtaagg
    22081 tcttgttttt tccatagaaa cggaacgaac aaagaccgaa atctgactga cgccatccaa
    22141 aatagcctgt gccaagattg atttagccgc accacctgca cccagcaggg tcatcttttt
    22201 acctgaaatt gtaaaagaag gcaagcactt aaaaaatccc ttgccatctg tattatatcc
    22261 aattaaattg ccattctcat tgacaaccgt attaaccgca ccaatcaagc gcgcttcatc
    22321 gcttagctca tccaaataag gaatcacctg ctccttatag ggcatggaca gattgatgcc
    22381 aaacatctgg tagcgacgaa tattggccac tgtttctgcc aagtcactcg cttcaatctc
    22441 ccaagccaca taagcaccgt tggtagctgt cgcctcaaag gctctattgt ggatgaaggg
    22501 agaaatagaa tgcttaatag gattggcaac aactgcagct aaacgtgtat agccatcaag
    22561 cttcatccaa aatctccctg atttttttca tgctagctag agaaatctgc ccaggggcac
    22621 taacctcatc cagactggca aaagaccaac tcgaaccagt cacatccgca gtgatacgag
    22681 agaccttgcc caccttaccc atagaaatgg tcacatattc ctgttcagga ttgagggttt
    22741 taaagcctcg tgtatagttc atcaagtcta agacatcctg ctccgtgtga gccatcaccg
    22801 caaccttaac aagttttgga tttaggatcg tcaactctga caagatttcc atcatgttct
    22861 caggtgtttc ttggaaatta tggtaactca aaacaagatt tgggaagtcc agcatttcct
    22921 caaaaacatc cttgtagcta tagtactcaa aatcaatata gtctggttga tagagttgcg
    22981 caacttcctt gattagatgg atatactctt ctggagaaag gtcgatttct ccaccttcgg
    23041 agcgagttcg tagcgtgaaa accaactcac ggcctgcgaa tttttcaaaa atggctggag
    23101 ctacctgcaa aatcgcttct ttaggcagat agtcggcacg ccattcaatg atgtcggcat
    23161 ccaggtacct cgtggcatcc agagcctgag cctcctctaa acttcttggc attactgaaa
    23221 cgattaattt catttactaa ccttcatact aatcaccttg aggtaattac tactttcatc
    23281 ttttttatta taggcaaaat ctgctggaag accatatttg tttaaaatct ggtaacttct
    23341 tcctgcaaaa cctttatcaa tttgttctgt aaatttctga cgggaaacat tggcagcatt
    23401 ggtactggca atgataatcc ctcccggatt taaaatctca agactctggg aaatcaactt
    23461 gtgataatcc ttggccacag agaaagtttg ttttttattc cgagcaaagc taggcggatc
    23521 taggacaatc acatcgtagg tcaagtcttt gcgtttggca tatttgaaat actcaaagac
    23581 atccatgact ataaaacgat gctcgtctgt gctgagccca tttgcctgaa aatgcgcttg
    23641 agacaattct cgtgaacgtt tggctagatc aacagaagtt gtctggctag ctcctcccat
    23701 ggccgcagct actgaaaaag ccgctgtgta ggaaaacata ttgagcaagg atttacccat
    23761 agccaagccg tcaactaaac taccgcgaac ctcatgctgg tctaggaaaa tccctgtcat
    23821 caagccatca ttcataaaga cttgatacag gacaccattt tctaaaacag tgaaaaagtc
    23881 aggtgcttct tgaccataaa catgggcaga ttcatagtca aaacccttaa agcggatttt
    23941 ctcataagcc cctaaaacct cagggaaaac ctgtctaaag gcttctgata tagtctgacg
    24001 aatctgataa acataagagt tataccaaga aaagacggcg tagtcgccat aaaggtccac
    24061 tgtcagaccc ccaaagccat ctccctcttg attaaagaga cgaaaggcag ttgtcaaatc
    24121 atcttgatag taggcgtttc tcttttcttt ggcttttcta aacaacgttt caaagaaagc
    24181 ttgattgaag gtcaccttgt ctttgctgat aaaccagccc aagcccttgt tttgctgaga
    24241 aaggtaggca gtcccaagaa agtttccttc ctgaccctgc acctctactt cccgatcctt
    24301 aagattgaca ttctcaagat cactggcttc tagtaaaact agccccttag caagcttctt
    24361 ttcaaccctt ttgctgactc ttattctatt cataactacc attatatcaa acttttagac
    24421 aattctcaaa aaagaaacta cccttgcttt tttactcttc ttttaaaaaa tggtatacta
    24481 gacttcctgc aaaactagga aataaatgtg taagaatcac aataaaaaat gctcttccgt
    24541 cttggaggag catttctttt tatcaacgaa aatcaaatag caaactatga aactagcctc
    24601 aggttaaccg tgagattata ggtagagagg ttgtatcagc aatatgtgtc tgtcaaattt
    24661 agtgacaaag gtagtagaag aaagatgaag aaataaatca gcttcagtag atatctggaa
    24721 aatttgattt tatagaaaag ccttttgtta caaactcaat atactatcaa taaataatat
    24781 tatagaagca acaataatta aaatttcacc tatttgcatc attctatttc gaactctaaa
    24841 tatatgttct atcaaaaata cttggatcac acacattata ggaattaacg tttttgaaat
    24901 tgaaaaatat cccaataaat aaactataaa caacaataat agaactatat tatatttctt
    24961 attcaaaaca ttcctcccta tatttttgat taccaatctt aatcatttac aactacattc
    25021 taacaaacta taaaagcgtt tgtcgaattg aatttatcaa gcaagcgacc aaccagctca
    25081 tcttttttct atttctgcca atatgcgtga caggtaataa tgatagccaa aaatagcaag
    25141 agcaagcagg aggataagag ctcctactcc caagctgatg gcaaggatag tggagagaga
    25201 ctgaaccaag aatatgctcc caattacaag ggccatcagg attgcactat aaataaacaa
    25261 taaaactatg gcgactatgc catttgaacg attcaccagg tccgtaatgc tactccaatt
    25321 ggttgacaga tttttaacgt ccttaaagta atggtggcaa gaaaggatga cactggcaag
    25381 gatccatgcc acaataaggt aaatcatcga aatgatgggc aagcctagat atagagaaag
    25441 accaagtaaa gtcagaattg gtaaaaagga ctggacggca tatataatcc aaaatttcac
    25501 tttcacataa cgagcaaagt caaagggtaa actcttaaga aaatcaacat tttccctctc
    25561 caaggacaag gcaattgaat gcaggctggt gatattgtta ttgacaactg ctataaagag
    25621 agctataaaa aacaagggta accagtatgg aggatgaatg tctggaacta tctgagaatc
    25681 tcggattttg gaaatcagac cgatcatcat gagataagga aggaaagcac ttgtaaaaag
    25741 cactgtaacc acgccagtcc cctgtcccaa gagggtgagg tggtagcgta aaaccatgcg
    25801 gaaaaatccc tttttagtgg ttgaaattct ctccttgctg cgacgttctt ttttgacctt
    25861 atcctcacta ttaagcagga tcacgtcata aaaacgagga aggaccttct ttttggtcag
    25921 ataaagcagg aagagagtta gtcctatcca agcgagcaga cccactaagg cttctgtcga
    25981 aaaaggctcc actgctattt tgtaaaagat atgaagagga taaaggagaa atggaatgtc
    26041 tctaactttg tcaacaatac ttccaaaagt cgactgaaga aagaagataa atattaaagg
    26101 tatgagaact cctatcccaa tcatcacatt cgaaaaaata gactgatact ttctgaagac
    26161 cctagtttga gccaagaaat gcactgccac taccatcact agagccacag agacaaataa
    26221 taaggtcaag gacagtagca tcaaaggcaa acccagccat agagaaggag ctagcctaat
    26281 gtagaggacc agaaaataag ctaggattgg tacaattcca gttagagctg gcaaaaggac
    26341 agacagtcct ttagcaatta taatctctga ttctttaaag gcatagggcc tatacgatat
    26401 caaatcctta ctctcataaa agacattgta aaaggccgtt aaagaagttg aaaaggcaat
    26461 cactagtaaa atagcaatca tcgagctaaa ataaataggt atttcctcaa aaggaaaatg
    26521 aatggctata ttactaaaac agatgagcat caagagactg gaaaaaatgt aagaacttag
    26581 gactctagcg gaaacattta cttttttccc aggattctta gcctgcttct ttcgtagatt
    26641 agccagatta gcttcttgag atgaatagag gatattgata tcaactaatt ttttaatgac
    26701 cttgagacgc atctgaaacc tcctcttttc taccagcaag gctaaggtag atactttcca
    26761 aagactggtc tgggtggtct ttcctcaagt tctctacact accacaatag atcaaatgcc
    26821 cctttttcaa aatagcaatc cgatcacaga cttgctcggc tacctctagg acatgagttg
    26881 aaaacaagac cgtcttgcct ttttgtgcat gttccttcat catttgcttc aaatcaaagg
    26941 cggcctgggg atccaaacca gtcaagggtt cgtccaaaac ccaaatatca ggagcagaca
    27001 agagtgcccc aatgacaaag actttctgac gcattccgtg agaaagagtt tcaataacct
    27061 gatagcggtt ttcagcaaaa tcaaaaacgt tcaatagcct agctagacta gtctccaagt
    27121 cagagctagt cagatcatag gatgaagcga tcaattccca aaattcattg gccgttaagc
    27181 gtaaaaataa gtcaggcgag tctgctacgt agccaatctt tcgtttgatc gccaagcgat
    27241 tttccgataa ctcctgaccg tctaccaaaa tacgaccact gctgggtgaa atgatactga
    27301 ctagggattt tatggtggtc gattttccag ccccattatg accaatcaag cccataatct
    27361 ctccattttc aatctgcaaa ttgagattac tcaaggcctc tttatcacca tacaacttac
    27421 taacattttg aaattcaatc atgggacaac tcctatcttt atctgtatta tacatcgcta
    27481 tactagcact ttgatacaaa aaaatcaata ctttatttta agtagttaaa atagtttcct
    27541 tctatcttac gcaaacgttt gcgctaatag atgctttatg atagaataaa gaacaagatt
    27601 gacaagtaag aggaaacatc atgcaaaatc aaacactcat gcaatacttt gaatggtatc
    27661 tgccccacga cggtcaacac tggacgcgtc tggctgaaaa tgctccacac ctagctcatc
    27721 tggggatcag tcacgtctgg atgccaccag ccttcaaggc aaccaacgaa aaagatgtcg
    27781 gctatggggt ctatgactta tttgacttag gagagttcaa ccaaaaaggg actgtccgca
    27841 ccaagtatgg tttcaaagaa gactatcttc aagccattca agcccttaaa acacagggaa
    27901 ttcaacctat ggccgatgta gttctcaacc acaaggctgc tgctgatcac agggaagcct
    27961 ttcaggttat tgaagtggat cctgtagagc gtacagttga acttggagaa cccttcacca
    28021 tcaatggctg gactagtttt accttcgatg gtcgccaaga tacctacaat gacttccact
    28081 ggcactggta ccacttcaca ggtacagact atgatgccaa acgccgtaag tctgggattt
    28141 atctgatcca aggggacaac aagggctggg ctaacgagga attggtcgat aacgaaaacg
    28201 gaaactacga ctacctcatg tatgccgacc tagactttaa acatcctgaa gtcatccaaa
    28261 acatctataa ctgggctgat tggttcatgg aaacgactga tgtagctggt ttccgtttgg
    28321 atgccgttaa gcatattgac tctttcttta tgcgcaactt catccgcgat atgaaggaaa
    28381 aatatggtga cgatttctat gtttttggtg aattttggaa cccagacaag gaagccaatc
    28441 tggactatct cgaaaaaacg gaagaacact ttgaccttgt cgatgttcgt ctccaccaga
    28501 atctctttga agccagtcaa gctggcgcaa actatgacct tcgtggcatt ttcacagata
    28561 gcctggttga actcaagcct gacaaggctg tgacttttgt cgacaaccac gatacccaac
    28621 gaggacaagc ccttgagtct accgttgaag aatggttcaa gccagcagcc tatgccctca
    28681 ttttgttacg ccaagacggc cttccatgtg tcttttacgg agactactat gggatttcag
    28741 ggcagtatgc tcaacaagat ttcaaagaaa tccttgaccg cctcctagcc atccgaaaag
    28801 atttggccta tggagaacaa aatgactact ttgaccatgc taactgtatc ggttgggtac
    28861 gttcaggtgc tgaaaatcaa tccccaatcg cagtccttat ctcaaatgac caagaaaaca
    28921 gcaagtcaat gtttgtcggt caagaatgga ctaatcaaac ctttgtagat ttacttggta
    28981 accaccaagg tcaagttaca attgatgagg aaggttatgg acaattccct gtctcagcta
    29041 gatccgtaag tgtctgggca gtcaatacca tctaatagct cataataacc aagctaggtc
    29101 caagcggatt tggctttttt gtattcacaa aaagacctac ccaaatggat agatctttac
    29161 ttgattacaa tttacctgct actgcatcca acaattcttg gatcttagct tggttgcttc
    29221 ctcctgccat ggccatgtct ggtttaccac caccacgtcc atcgatgatt ggtgctaatt
    29281 ctttgacaag gtttcctgca tgaaggtctt ttgtcttgct tgctacaagg acattgactt
    29341 tgtcaccgat agcggcaact aggacaagaa gatcagagta gtctttttgt ttccagttat
    29401 ctgcaaaagt acgaagggca ccggcatcgg atacagacac ttgactagca atgtaacgat
    29461 gaccgttgac ttccttaaca tctttgaaga tatcgcctgc ggctgcagct gcggcttttt
    29521 ctttcaactc agcattttct ttttgaagtt gacgaagttg ttcttgaagt ccttctacct
    29581 tgtgaggtac ttccttgact tgaggtgctt tcaaggttgc tgcgacagct ttaagagcat
    29641 cctcttgttc acgataggct tcaaaggctt ccttaccagt cactgccaag atacggcgag
    29701 ttcctgaacc gattccttct tctttgacaa ttttgaagag accaatctca gaagtgttgc
    29761 caacatgagt accaccacaa agttcaatag agtagtcacc gatagtcacg acacgaactt
    29821 ccttgccgta tttctcacca aagagggcca tagctcccat ttctttagca gtgtcaatat
    29881 ccgtttcaac tgtcttcact tcaagtgctt cccaaatttt ctcgttaact tgctgttcaa
    29941 tcgcacgaag ttcctcagca gttactgctt ggaagtgggt aaagtcaaag cgaaggaatt
    30001 caacttcgtt aagagatcct gcctgtgttg cgtggtttcc aaggatattg tgaagggcag
    30061 cgtgaagcaa atgagtcgca gtgtggtttt tcatgacacg gtgacggcga ttgctatcaa
    30121 ttgccaaggt atattcttgg ttcaaggcaa gcggtgcaag gacttcaact gtatgaaggg
    30181 cttgaccatt tggggctttc tgaacattgg tcacagtagc cacaacctta cctgactcat
    30241 ccaagatttg tccgtagtca gctacctgtc cacccatttc agcataaaat gacgtttccg
    30301 caaagataag agaggcagtt ccttctgaaa cagctcctac ttctgcattg tcagcaacga
    30361 tagctaccaa tttagaagac aattggctag cattgtagtt gaagacactt tctacagtga
    30421 tgttttgaag agtttcattt tgcataccca ttgagccacc cttgacagct gacgcacgcg
    30481 cgcgttcttg ctgttctttc atggctgctt caaaaccttc acggtctaca gtcatatcag
    30541 cctcttcagc aatttcttca gtcaattcaa ctgggaatcc gtatgtatca tagagtttaa
    30601 agacatcttg accagcaatg acagattgac ctttttcttt caagtctgcc acaatgcctt
    30661 gggcaaagtg ttgacctgag tgaagggtac gggcaaatga ttcttcttcg ctcttaacga
    30721 ttttctcaat aaagtcacgt ttctcaagca cttctgggta gtagctttcc atgatttttc
    30781 caacagttgg aacaagtttg taaaggaaag gctcgttgat acccaatttt tgaccatgca
    30841 tagaagcacg acggagaaga cgacgaagaa cataaccacg accttcattt cctggaaggg
    30901 caccatcacc gatagcaaat gaaagagaac gaatgtggtc tgcgataacc ttgaagctca
    30961 tgttgtcgcc atcttggtca taaaccttac cagacaattt ctcgacttca cggataatcg
    31021 gcataaagag gtccgtttca aagttggtct tagccccttg gataacagcc accaaacgct
    31081 ccaaaccagc gcccgtatca atgttcttat gtggcaattc cttgtatttg ctacgaggaa
    31141 cagcagggtc tgcgttaaat tgtgacaaaa cgatgttcca gatttcaata taacggtcgt
    31201 tttcaatatc ttctgcaagc aggcgaagac cgatattttc tgggtcaaag gcttccccac
    31261 ggtcaaagaa gatttctgta tctggtccag aaggtcccgc accgatttcc cagaagttgt
    31321 cctcaattgg aatcaagtga cttggatcca ctcccacttc aatccagcgg ttgtaagaat
    31381 ctttatcgtc tggatagtag gtcatgtaaa gtttttcagc agggaaatca aaccattcag
    31441 ggcttgtcaa aagctcataa gcccaagtga tagcttcgtc acggaagtaa tccccgatag
    31501 agaagttccc cagcatttca aacatggtat ggtgacgcgc agtcttccct acgttttcga
    31561 tgtcgttggt acggatagcc ttttgggcat tggtaatacg tggattttca gggataatgg
    31621 tcccgtcaaa gtatttctta agggttgcta ccccagagtt gatccacaaa agagttgggt
    31681 catttacagg aaccaaactt actgatggtt ctactgagtg acctttggtc gcccagaaat
    31741 caagccacat ttggcgtact tgtgcactag atagttgttt catattgtct ccttattcac
    31801 ttgtttaatg tgattggctt tccagcattt ccacatagtc aatcgcgaca cagagggaaa
    31861 tgactaggtc tgcataagcg tcttcaagaa ccgttacggt ataggtagaa gtcagatgga
    31921 agagttcctt cttaatttcc gcaatcaact gatcgcgatc atccagcaat ttgaaattca
    31981 aatcccagat attgccctcg atacgaagac ctagattatc aaactcatac ttatctcgcc
    32041 agaaggtcaa cttcttacga atgacaaaac tcgagccatc ccgaagctga atctcaaaat
    32101 gaggaagtaa ggtcaagatt tctttactaa tctcactgac ttgttcacca gccgcatcat
    32161 agatggtaaa ggttttagga atcttaaaaa atgatccctc cacctgatag gcaatttctc
    32221 ccctgtcatc cttgatagcg aagcgttcgc ctccaagacg aaacttttgt ttgacaagaa
    32281 atgttttcat caacacctcc aaaaatcaaa agacaagctc atatcacgaa gggcgaaaaa
    32341 ccgcggtacc accttcattc aatgaacttg tcattctctt gttcttatgc aattgtatga
    32401 ttgagtagca tgacttccta gcttagatgg ctcgcagcac cgccatttct ctggactaag
    32461 acaagtgaaa atcaattctc aactttctta ttataacgtt tttttaagct tgcgtcaact
    32521 ggaaatgatc tccgttgaat tagaccaatt ccctacatct ctgattactt tttcaggata
    32581 tattttttct tactgccatt tttcttttta tcccaaattt tcatattact aaacacagct
    32641 actagaatat ttccaaatat aaaggtgcct atcacccaat atatggactc agttgttagg
    32701 tattgtcgat ccaagccatc ctttaaatgg aatagtatag cagtttggtt aacaatcata
    32761 aaggttggcc agaaactttt tttgaaaaaa gtagacattt tcattatttg ttgccgcttt
    32821 ctgtaaggtt aatactcaat aaaaatcaaa aagcaaacta ggaagctagc ctcaagctgt
    32881 acttgagtac ggcaaggcaa cgctgacgtg gtttgaagag tataggctta gtatactact
    32941 aggcaagcaa ataagcaaat aaacaaataa acaactagaa tagaaaaaga tagggctcta
    33001 aaaactgact tctattcctt aaaaacgaac cagcttgact gattcgtctt cttacgttta
    33061 tctcctactt ccgatacatt ttaaactgta ggaagaggtc gctatatttc cctgtccatt
    33121 tatggtcaaa tttctcataa atttctaggt gtttcatggt ttcaacatcg ggatagaagg
    33181 ccttatcttc ctttgtttcc tctgggagca attccttcgc tggtaggttt ggtgttgaat
    33241 agccgacata ctccgcattt tggagagcat tttcaggttt caacataaag ttgataaagg
    33301 cataggctga gttttggttt ttaactgttt tgggaatgac catattgtca aaccaaagat
    33361 tgctggcctc tgtcggtacc acataacgta gattttcatt tttttctaac atttggctgg
    33421 cttcaccaga gaaggtcacg ccgattgcaa cattattctg aatcatatag cccttcatct
    33481 cgtccgcaac gatagccttg atatttggag tcagtttgta gagcttatcc actgtctctt
    33541 ccaactgctg cagatccttg gagttgaggc tgtagccgag ggaattgagt cctagtccca
    33601 gcacctcacg cgccccatca aagagcatga tagaattctt atactccggc ttccaaaggt
    33661 catcccaatg ctcaggcgct tcatctacca tggtttcgtt gtagataatt cctaaggttc
    33721 cccagaagta agggatggag aatttattac ctgggtcaaa ggactggttg agaaactctg
    33781 gtccgatatt ttcgattcct tcaatttttg aataatcaag cggaaccaag aggtcttcgt
    33841 ccttcatctt gttaatcatg tattcacttg gaatggcaat atcgtaggtc gttccaccct
    33901 gctttatctt agtgtacatg gcttcgttgg agtcaaaagt ctcgtactga acttgaattc
    33961 ctgtttcttc tgtaaactga gtcaagagtt caggatcgat atagtctccc cagttataga
    34021 taaccaattt ttgactatct cgactattga ttttactatc taaatgagtc gcaattcccc
    34081 acaagacaag gataatcgct gcaattcctg ctaaaaatga atagattttt ttcatgcttg
    34141 ctcctccttc tcacgagaga taaagtaata acctacaact aggataatac taaagagaaa
    34201 gactagagca gacagggcat tgatttctaa ggaaatcccc ttgcgagcac gagagtaaat
    34261 ctcgactgat agggttgaaa agccatttcc tgttacaaag aaggtcacgg caaagtcatc
    34321 taacgaatag gtgaaggcca tgaaataacc agtaatgata gacggagtca ggtaaggaag
    34381 catgatttcc ttgaacatct gaaattgact agctcccaag tcataggccg catgaatcat
    34441 gtcgccattc atttccttga gtcgaggcaa gaccatcaag accacgatag gaatggagaa
    34501 ggccacgtga ctagatagaa cggtcaaaaa gccaagtgaa aacttgagtt gggtaaagag
    34561 aatcaagaag ctagcaccaa tcataacgtc aggcgcaacc atgaggatat tattgagtga
    34621 tagaaaggct tcttggtatt tcttacgaga ctggtagatg taaatggcac caaaagtccc
    34681 gataatggtc gctatcaagg ctgataggaa ggccaagaaa aaggtctgag tcacaattaa
    34741 cataaggcga ccatcaccaa acatggtttt aaaatggctc aagctaaagc ctataaagct
    34801 gttcatgtcg tttcctgcat taaaggcgta gccaatcaag taaaagatag gcaggtagag
    34861 gaccagaaag accagtccca gataaaggtt ggcaaatttt ttcatcgttc tctcctttcc
    34921 ttagtcaccc acatggtgat gaacatggtc aggatgagaa tcacaccgat ggttgaaccc
    34981 ataccatagt tgtcattggt tagaaaattc tgctcaatag ccgtccccaa ggtgataacg
    35041 cggttcccac caatcaaacg ggtcagcatg aagagactca aacttgggat aaagaccgac
    35101 tgaaccccac ttcgcacacc gttcatagat agagggaaga tgacatgacg gaaggtctcc
    35161 cacttagttg caccaaggtc ataactagca ttgatgagat tattatccat atcgtctaag
    35221 acattgaaaa tcggcaaaat cataaagggg agctcgatgt agcttgcgac aaagataaag
    35281 gaaaaatcgg taaaaagcaa ctgttgtgaa ccaattccga taaattccaa gaattggtta
    35341 atagagccat tttgaccaaa aatcccgata aaagcatagg ctttaaggag caaattgatc
    35401 caggtaggaa ggataatcag catgagccag agttgacggt gcttgagacg ggtcaaaaag
    35461 agggctgttg gatagctgat aagcaaggtc acaaaggtca caatccctgc ataaagcact
    35521 gagttgaaac tcattttgag gtaggtcaag ttttgtgacg caaagtaaga tttataattt
    35581 tctaaactaa actggccttc aatgttgaaa aaggattgtc cgaaaatcaa gaccaagggt
    35641 gccaatacaa agagggcaat ccaaagcatg tagggcacta caaagagttt agagcttgtt
    35701 ttcttcatct ctttcctcct cgatcgcatt gatcagacct gcttcttgct cttcgatttc
    35761 cacgtattct tcgatacgag catcgaactc ttcttcggtt tcattgagac gcatgatgtg
    35821 gatgtcttct gattcaaagt ccagaccgat ttcctcaccc acgatggcct tacgggttga
    35881 gtggatcatc cattcatttc caagttcgtc ataggcgata atttcataat gaactccacg
    35941 gaagagctgg gtgtcgacct taacttggag tttgccttct tcaggaaggg taatgcgcaa
    36001 gtcctctgga cgaataacga cctcaacagg ttcatttggc ttcatcccac catcaaccgc
    36061 ttcaaagcgt ttgccgttaa attcgaccaa gtagtcctca atcatggtac ctggcaagat
    36121 gtttgactcc ccgataaagg tggcaacaaa gtggttgatt ggctcatcgt agatgtccac
    36181 aggggttcca gactggacaa tctcgccatc attcataacg aaaatccagt cactcatggc
    36241 aagagcttct tcctgatcgt gagtgacaaa gacaaaggta atgcccaatc gttgttgtaa
    36301 ttcacgcaat tcgtactgca tgtctgttct caatttcaag tccagcgctg ataaaggctc
    36361 gtccaacaag accacacggg gttggttgat gatagcacgg gcgatggcca cacgctgacg
    36421 ttgtcctcca gaaagtttgc ggatggaacg tttttcataa ccttccaact gaaccatctt
    36481 gagaacttcc gctacacgct gctcaatttc tttcttatca attttacgca agcgaagtgg
    36541 aaaggcaaca ttttcaaaca cattcatatg tgggaacaag gcataggatt ggaagacggt
    36601 atgtacgtcg cgcttgttgg ttggaatatc attgatacga acaccgtcta gcatgatatc
    36661 tcctgtcgtc gcatccagta aacctgcaat aatgtttagg atagttgatt tccccgaacc
    36721 agatgcacct agaagggtgt agaatttccc ttcttccaac tcaaagttga tgtctttgag
    36781 aaccttggtg ttgctgtctt caaaaacttt agagacgttt ttgaattcga taattggttt
    36841 tttcaattgg cataaattcc ttctttttca tagattaacc gatcggggct ctgtcaggtc
    36901 cccactacct cttgcaggga gtaaaaccac ctgcatacat cttcgctacc gataggcttt
    36961 cacccaagat ccggacttct ctttcaagcg taatacctga gtgttccttg actttttcga
    37021 taaccgattg gatcaagtcc tcgtagtctt tggccgttcc atctgcgaca ttgatcataa
    37081 atcctgcatg cttttctgac acttctacgc caccgatacg atagcctttc aagccagctt
    37141 ctgaaattaa ctgacctgca aaatgcccga ctggacgctt aaagaccgag ccacaagatg
    37201 ggtattccaa aggttgcttg agttcacgta ggtgcgtcaa gcggtccatt tcctgcttga
    37261 taacctgatg ggttcctgga gctagggcaa atttaactga caagacaact gcaccagact
    37321 cctgaatagc tgaatgacgg taaccaaaag ccaagtcttt agcagacagg gtttcgattt
    37381 ctccatcctt ggtcaagacc ttacaagact gcaagatgtg agcaatctcg ccaccatagg
    37441 cacccgcatt cataaagaca gcaccgccaa cgcttcctgg aataccacaa gcaaactcaa
    37501 agccagttaa actatgacgg agggcaatgc gagttgtttc aatcaagtta gccccagctt
    37561 ctgcttcaat ggtatagcca tcaacagaaa cgttattgag cttgtcacac aagatgacaa
    37621 atccacgaat cccaccatca cgaacgatga tattgcttgc attgccaaga accatccaag
    37681 ggatattttc ttggttggca aatttcacaa cgcgagccaa ctcaaaacga tttcgtggaa
    37741 agaccaaata atcagcctct ccacctactt ttgtataact atagctatgc aagggttcct
    37801 taaaacggat atcaattcct tctaagattt caagcatttt ttctcttaca gacatgtcac
    37861 tcttcctttt acaaaattca ttccattata ccatttttag agacatttga cgaccataaa
    37921 aataccttgt ttggattttg cataagaaaa agaggttccc ccctttttat gattttttac
    37981 aaaagatttc cttggttcca taggcgacca gaacgagctc cagtgctaga atcacttcaa
    38041 ccaagactgg atttgtcaac cagcctactt ggaaaagaga tggtgccaga tcaaagaagg
    38101 catgcaagcc atagggtgct aggagataaa tccatttctt ctggcgaaca gcttggtaaa
    38161 cccaaactgt caaaagtaat tggaaaccaa gcgccaagat tcgctcaaaa ccaagcaaat
    38221 aaatctgcca gaccgaaagt gactgaatgg tttttaacat attttcagac agtaattgca
    38281 taacctgtgg attctgagtt tgaactgccg aaagaacgat gtaaagattg agtaaactag
    38341 taaggcctag aaaaatcaac tccaagccac catgccctag gccataggcc aaggcatctg
    38401 ccttttccaa acttctcttt ttctccaacc atttgaagaa aacaagacga gccgtttcct
    38461 caaaaaatgc tgccatggct aggccataga taatatagat aagcggatga tcttgcaaga
    38521 gggcaatact accgtctttt tgagggtgca aaatcaagat atgcaccagt ttttccaaaa
    38581 tctgcgaaga gacaaagaaa gcgactgcac ccaagcccaa gacagctaga ttaatctggt
    38641 atttcttttt ggcaaaccaa atgcttccta tcagaaaagc tagcaacagc aacatggtaa
    38701 taatgatatg aatggtcatt ttcttctcct attctgcctt ttcaatatct tttttcatct
    38761 cgtcaacatt gaacttagca aacaagtatt gacggtcttg gactgggaaa cgttggtcca
    38821 actggtcaac tgctcccacc tcgataatgc cttccttgat gacaaaatcc atgacatgtc
    38881 caccgaaggt caaatcatct gatatgaagt gcagatggta gcctgccaca ctgaccccat
    38941 ggaaaatctc aggcgtccag aaaccaacaa tagtccccgc aacattgtca cgactatatt
    39001 ccggttgatg ggttgcgaca tcagcaaact tggtatcggg tgttgactta ggaatcatac
    39061 gcacatgcat atgtgaaaat cccccccgaa tcttgataga gcggaaaaga ttttccccat
    39121 cataataaga ctcaattcgt tctttcaatt ccttgtctgt catctcaaag cgctggcgga
    39181 aaatgacctc tgcctgatgc ggtaccactg cagcgtaagg aataagggca tctggtgaca
    39241 cttccacaat ttctggctgg tctcctgacc ctttggcctg ataagccttg ccatccaaga
    39301 caatcaattc cccatcaatg gaatccaagg ttcccaaacc aaggtcacca tgttctagca
    39361 attctcctac tgtcatagta ccaccataaa ggccagccat caaggctcca agagtattgt
    39421 attgaaataa tttcactggt tcctgcacgt tcttatccat tcactttctt gtctgttatt
    39481 ctataaatct tactcctaag tataccacat ttgcccctag atgtgaacga gagaaacgct
    39541 ctagacattg ccaagaagga aaaaaaaggg tacaatgtaa caaaatcaag ggaggtctgg
    39601 aatgaagaaa caaagcaagt acaaagaggt cgtttcctat ctgaaaaatg gtatcgagtc
    39661 tggacgattt ccgacgggaa gtcgcctgcc ttctatccgt caactgagcc ttgacttcca
    39721 ctgtagcaag gacaccattc aacgagccct gctggaatta cggcacgaac aatacctcta
    39781 tgccaagccc cagagtggct actatgtcct agaacaaggg caacaccagg acctagaaat
    39841 cgaggttacc gacgaacatg ccagtgccta tgacgatttc cgactctgtg tcaatgaaac
    39901 cttgattggc cgagaaaact acctcttcaa ctactatgac aatcaagaag gattagaaga
    39961 cctaagacaa tccattcaca aactcctctt tgagcaagct ctctactgca aggctaacca
    40021 actagtactg acttctggaa cccaacaagc cttgtttatc ctctctcaaa tatcctttcc
    40081 tagccaagcc aaggaaatct tggtggaaca gccaacctac catcggatga atcgcctctt
    40141 gattgcacag gggctggact atcaaacgat tgaacgaggc attgatggga ttgacttgaa
    40201 ggagctggag cgacacttca agacaggaaa aattaagttt ttctacacca ttccccgatt
    40261 tcactatcct ctgggacatt cctattctga gcaagacaaa cgatccattc ttaacttagc
    40321 tgccaagtat gatgtctata tcgtagaaga cgattatctg ggtgatttgg actccaagaa
    40381 gggccaaacc ttccactatc ttgatacaga ggagcatgtc atttatatca agtccttctc
    40441 gaccagcctt tttcctgccc ttcgtattac agcactcatt cttccaaatg ctatcaaaga
    40501 agcatttgtg gcctacaaaa atatcctaga ctacgacagc aacctcatta tgcaaaaggc
    40561 cctgtcactc tatattgaca gtcaattgtt tgaaaaaaat cgtttggctc gcttgaccaa
    40621 tcatgaatct taccaaaaac aaatcgagga aaggataact aaaacacctt gtccccttcc
    40681 tcattatccc ctacacgatg gtttattgct agacctgaga cagtatccta aaatcgccag
    40741 tctcaaacac agtcaaccgg gcttggactt ctttgaagag gcctatttaa gtacctgtcc
    40801 ttatcaattt gccaaggtgt ccctagacaa tctggaaaat gttttaaact atttaaaagc
    40861 agaattggaa tgacatccaa ctctgctttt tcttattctt caacttcagt tagacttgct
    40921 gctttttcaa gatagctttg gtaaattcct tcatccttaa gtttttggat gaccttgtct
    40981 accacttctt tcaaatcatc actatttttt ctaagagcaa cggcattggc gtcgccgtcc
    41041 ttcatcttca agctgacagt tgcgacagct aagccagcgt ttttagcagc ataactaagt
    41101 gcaacaggct catccatatg aacagcatct acttttccag cctgcaattc attgactgct
    41161 tcacccatat tagttaggga agttaattga gcttttggca attgttcctt gaccattgat
    41221 tctggaacag tccctttttg ggctgcaata ttagcacttt ctaggctagt taaatccttg
    41281 tatttttcca catcagcctt acgaaccaag aaactaatct tgttttcata gtatgggatt
    41341 gaaaaatcaa agacttcttt tctctcgtca gtagcactaa ttcctgcaac tgctaggtca
    41401 gccttaccag tttgaagact ggtcaaaaca ttgtcaaaac tcatgcttga gatttccaac
    41461 ttaaccccaa gttcatcagc gatagcctga gccatgtcga tgtctgcacc gactacctgg
    41521 ttctttccat caaccaatga ttgaaattca aagggtgcat agtcaggact ggttgccaca
    41581 actaatttcc ccttttgctt aatggcctca acagctgact gagaaccatt agaacctgac
    41641 tggcaagcta ctaagaagaa acttgcaaga aaattacata aaacaaatat ccattttttt
    41701 gatttcataa ataaacaacc tctctgttaa ttttgtataa ttataacgat atccaagtta
    41761 cttgtcaagt gttttttaaa tttttatctc aaaaatattt tttcgttcaa aaaaaggagc
    41821 catcagttga tttcaagctc ctttttatac agaattaaac tattttatag ttcgacaatc
    41881 ttacctgttt caaagtagac aacccattca cagatatttt tagcatagtc accgatacgc
    41941 tccaagtagg aaataacttg gaaataatca cgacccgtaa caatggcttc tggatttttc
    42001 ttaatctctt cagtcgcaag gtcacggata gtttcaaaat agtggttaat ttgctcatcc
    42061 atggaggcca cccggtatgc gtcgtcaaca gaaccattaa gataaagatc aagtgctgct
    42121 tcaacaacgc ttttaacttc acgtcccatt ttttttattt cttcctctac agctggaata
    42181 cgttcttccc ccttcatacg gatggttgcc tgggcaatgg ctacagcgtg atcccccata
    42241 cgctccacat ctgatacagc cttaaggaca gtcaagactg tacgcaaatc ttgagagact
    42301 ggttgttgga gtgcgatcat ttcaaatgat ttcttttcca gtttcacttc gtattcattt
    42361 acttctgcat catcttcgat gacctctttt gccaggtcac ggtcatgcgt gacaaaagca
    42421 cgtaccgtac gattgatttg tgagagcact tcttgtccca tagcgtagaa ctggttatgt
    42481 aatttctcta aatcttcttc aaattgagat cgtaacatct ttcatctcct tatccaaatt
    42541 ttcctgtaat atagtcttcc gtttccttgt gttggggatc aaggaacatc tgcttggtat
    42601 cattaaattc aatcaaatct ccatctagga aaaatcctgt cttatcagag atacgtgaag
    42661 cttgctgcat ggaacgggtt accagaagca tggtgtactt gtcttttaga ccatacaagg
    42721 tttcctcaat tttaccagct gaaatcggat ccaaagccga agttggctca tccaagagga
    42781 tgattttagg actagttgcc aagacacggg ccacgcagac acgctgctgt tgaccacctg
    42841 acaatccaat agctgaatca tatagacgat ccttgacctc atcccaaata gaggcacctt
    42901 gcaaggcttt ttctacggct tcatccagaa cctgcttatc cttaattcca ttgatacgaa
    42961 gcccgtagac aacattctca tagatagtca tagggaaagg attaggttgt tggaaaacca
    43021 ttccgatttc cttacgtaat tcaaccgtat ctgtacgcgg actgtagatg ttgtgaccat
    43081 tgtacaccac ggatccagtt gtggtcacct ctggattgag atctcccatg cggttgagag
    43141 acttgaggag ggttgacttc cctgatccag atggaccaat caaggctgta atttccttag
    43201 gttggaaaga tagggaaaca ctattcaaag ccttcttttt attataataa acggacaggt
    43261 ctgatacctg taaaatcgca tctgtcatac ggtttccttt ctaaccaaag tgaccagata
    43321 catagtcatt ggtggactgt agcttggcat tttggaaaat agttgcagtc ttgtcatact
    43381 caatcaaatc acccaagtaa aagaagcctg tatagtcact tgcacgagca gcctgctgca
    43441 tattatgcgt tacaatgatg atggtaaagt ttttcttgag ctcaaacatg gtctcttcta
    43501 gttgcatggt cgcaatcgga tccaaggctg aggctggctc atccattaag aggatatctg
    43561 gcttaacaga gatggcacga gcgatacaga gacgttgttg ctgaccacct gataaggtca
    43621 aggctgactt gtggagatcg tctttaacct gatcccagag ggcagcctga cgaagggagg
    43681 tttctacgat ttcatctagg acttgcttat ccttaactcc agcacgttca tgcgcaaagg
    43741 taatattacg gtaaattgac ttagcaaatg gattggggcg ttgaaaaacc attccaatgt
    43801 gtttacgcat ttcataaacg ttgatttctg gacggttgac atcaattcca cgatagagaa
    43861 tctgcccagt tactttagca atatcaatgg tatcattcat gcgattgaga ctgcgtaagt
    43921 aggtagattt ccccgatccc gacggaccaa tcaaagctgt aattttattt ctttcaaatt
    43981 gcatatcaat ccccttaatg gattcatttt taccatagta aacatggaca tccttagtag
    44041 aaagggctac tttttcttca ggaaaggtaa ggatatgctt ctcatcccag ttatatgttg
    44101 acatggcttc tcctttaggc agcggttaat ttcttgtgta gatagcttcc gaacttacga
    44161 gctccaaagt taaaaatcag gataaagatc aggagcacag cggcagaacc tgctgataca
    44221 atggttccat ctggaatagt gccttcacta ttgactttcc agatatggac agccaaggtt
    44281 tctgcttgac ggaagataga gatggggcta gtcacactga ggatattcca gttagaccag
    44341 tcaagagctg gcgccgattg ccctgctgta tagatcagag ctgcagcttc gccaaagata
    44401 cgaccagatg ccaagacgac acccgttaca atacctggaa gcgcttctgg aataacaaca
    44461 tgaaccactg tctcccagcg agaaatccca agagccagac cagcctcacg ttgggtatgg
    44521 tgaacgtgtt tcaaactatc ctctacatta cgcgtcatct gaggcaagtt aaagactgtc
    44581 aaggccaagg cacctgaaat gattgaaaat ccatactcaa actggactac aaagatcaag
    44641 taaccaaaga gacccaccac cactgatggt aaagaggaca agatttcaat acaagtccgc
    44701 acaaagttgg taacaggacc ttttttagca tattcagcca agtaaatccc agctcccata
    44761 gaaagaggta cagaaataat caaggtaatg accaatagga aaaaggaatt gtaaagctga
    44821 atgccaatcc caccacctgc ttgaaaagca gaagaccttc cagtcaagaa agaccaagag
    44881 atatggggca agccccgaac caagatatag agaatcaagg aagccaagat tgtcacaatg
    44941 atgctagcaa tcgtatagag gacagctgtt gcaagtttat ctaatttctt agcgcgcata
    45001 atttttcttt cctctttctt tcgtaatcaa tttaatcaca ctgttaaaaa ctaaactcat
    45061 caagagcagt accaaggcca gtgaccagag aacattatta tttacagttc ccatgacagt
    45121 gttcccaatt cccatagtta atatagaagt taaagttgca gctggtgtgg tcaaggaagt
    45181 tgggataaca gctgagtttc cgacaaccat ctggatagct aaagcctcac caaaggcacg
    45241 cgccatccca aagaccactg cagtgaaaat accagaacgg gccgccttca agatcacacg
    45301 ccagatagtc tgccagcgag tggctcccat agcgaaacta gcctcacgat aataacgagg
    45361 aaccgcacgc aagctatccg ttgtcataaa ggttacggtc ggcaaaatca tgacaaagag
    45421 gacggaaatc cctgacaaaa tcccaaaacc agtcccacca aagacactgc gaacaaaggg
    45481 aacgacgact tgcaagccaa taaatccata cactactgaa ggaatcccaa ccaggagttc
    45541 aatagctggt tgcaaaatct tcgccccttt tggtgatact tcggtcataa aaactgctgc
    45601 accaatagca aagggtgttg cgataagggc tgagagaatg gtaacgataa aggaacccaa
    45661 aatcatagga agggcaccaa attctttact agaaggattc caagttcctc ccaaaagaaa
    45721 gtcaaagata ttcacaccat tgacaaagaa ggtcgacaag cctttttgcg ctacgaaaac
    45781 caaaatcatg gccacaagga tgactatcaa agaaagacag gcaaaggtca aaccttttcc
    45841 taatttctcc agacgagaat tctttgatgg aagcaacatt ttcttagcta attcttcttg
    45901 attcattatt gtctcccttc caacactgtc acagttccgg cagcatcttt ttcaaccttc
    45961 atttccttaa tcggaatata cttcaatcct ttgacaatcc cttcttgggt ctcatccgag
    46021 agaacaaaat tgagaaattc tgcagccaac tcattgggct gccccaatgt atacatatgc
    46081 tcataagacc acaagggcca attattgcta cttatatttt ctggacttaa gtcatagcca
    46141 ttcaacttca tgcttttgac cgaatcatct atataggtaa gagataaata agagatagct
    46201 cctggacttt ttgatacgat tgattttacc gctccatttg aatcctgctc ctgactttgc
    46261 atggcagact gaccttccat aatgacagta tcaaaggtag cacgagagcc agagccggct
    46321 gcccgattga taacagagat gggtaagtcc ttaccaccaa cttctttcca attggttacc
    46381 tcacctatga agatttgacg aagttgctct gtcgttaggt tatcaacatc aacctcctta
    46441 ttgacaatca gagccaagcc agctaccgcg accttgtggt caacaagagc agaagcatca
    46501 attccgtctt tttcctcagc aaatacatct gagtttccta tatcaactgc cccagactga
    46561 acctgggaca agcctgtacc agaacctccc ccttggacat tgaccgtttt tccaacatgg
    46621 atcgtgccaa attcatctgc cgctacttca accaagggtt gcaaggcagt tgagccaaca
    46681 gccgttatgg attctccacg atcaatccag ctagcacagc ctactaaaca agccgtcagc
    46741 caaaaagcga taagagacag agcaagcttt tttctttttt tcactgtttt tctcctcgaa
    46801 aataattatg aatactgtga attttttaag tagttcttta tgagttgacg catgaattct
    46861 taccaaattt ctgcgcaatt gattatttat ataatatagg ctatattact ctttcctaac
    46921 ctcctttttt catatgtgga taaaatctct tgtctatccc ttccaccatt gtcacccatt
    46981 atagtcattt cgtgtctctt tttccccttt ttaatgcaag ggaaattact ctcctcagat
    47041 gataatccaa aagctagaaa ggtatctcaa acctctctac tctcccagac tagtttacaa
    47101 ctaaaaggaa aagattctat tttatgagaa atctagttta caagcggtaa gaacgctaat
    47161 aactaaactt cttgtactct ttgaaaatct cttcaaacca gtgttttgag ctatctatgg
    47221 ctagcttcct agtttgctct ttgattttca tcgagtagta aaactacatg tgatggcaat
    47281 caagatatca agaatcatcc tactaaaaaa atccatactt tcactataac atagaataag
    47341 atatttgact agcattttca tttgaatctg aggccttttg gaaaataatt tttcaaaaca
    47401 tttccagtaa cctttgcaaa gcccaagcca ttgcctttaa ccaaaacttg gtaccaacca
    47461 tttggcagac tttctgccag ctgaacgatt tctccagccg catacttgac aaacgcttct
    47521 tggccaattt caaccgactg ttcgacctga ctcggtttca aggctaaacc aagagcgaaa
    47581 ctgggctcaa agcgtttctt cttaaaagtg cccagatgca gtccattgcg agcaatcttg
    47641 agcttcccta aatctggcaa aagttctggc aagagataaa gctggtctcc aaaagtctgc
    47701 aagatacccg gtagattgac cttcaaatgg ttttgggcaa attcctgcca caaggcaact
    47761 tgttcacggc tgaggttact cttacttgcc ttaaatttag gagctggatt gttaccctta
    47821 aactgtagat gggcaacaaa ctgaccctct cccttaaact gatgagggta catccgagcc
    47881 gtttctggca ggtcaatacc agctaccatt ccattgatat gctctactgg aaacaagtca
    47941 aaatcatact cttccagcaa ccaattgaca atctcttcgt tttcctcggg tgcccaggta
    48001 caggtcgaat aaaccagacg accaccttca gctaacatgg tcactgcatc ctccagaatt
    48061 tctctttgca agctagcaca ttgactcgga taatctaagc tccaatagtc catagcatca
    48121 ggttgcttac gaaacattcc ttcaccagag caaggggcat caagaacgat taagtcaaaa
    48181 tagcctttaa agaccttgac caagcggttg gcagattcat tggtcaccac gacatttgtc
    48241 gctccaaaac gctccatgtt ttcaaccaaa atcttagccc gtttgcttga aatttcattg
    48301 gaaacaagta gcccctcccc tgctagatag gctgccagtt gagttgattt gccccccggt
    48361 gcagcagcca agtccaagac cttcatacca ggactgggtt gggctacttg agccaccatt
    48421 tgagcagcag gttcttgcga ataaactaaa cctgtagcat gctcaggcga tttccctgaa
    48481 accttcccat agtggcccca aggggtttga gtaatggcat cagaaaagga aagttgctct
    48541 tcttttaagg gattgacccg aaaggccgaa accgcttcct cctcaaaaga ggcaagaaaa
    48601 tctcttgcct catctcctag tatctcttca tatttttcaa caaatccttc tggaaattgc
    48661 atttaagttc ttttcctttc gtaaatatag gactgaattt cctcctgcat ctcaagaggt
    48721 agcatcatga ccggttgtct ggtttgaaaa tcaggagcct caccagatag agtcacaacc
    48781 cgatagccca gactttcccc taaaatacta gccgcagcat aatcccatgg ttgcagatag
    48841 gtgacatagg tcaataaatg ccctgacaaa atcttggcaa aactaatagc cgcactccca
    48901 tagacacgta caccgaggac cgctcgactc aaatcagcca gcccccattc gttggtttcc
    48961 agcatgccac tatttcccgc aatgagaaaa tctccaagtg gttttgcttg aaagggagct
    49021 aggggcttat cgtttcggca aaccggaaat tccccaccac catggtaaca atcccctttg
    49081 accacatcat aaatcagacc aaactgtccc tgaccatttt caaaataagc catcataaca
    49141 gcaaaatctt cctgctgggc tacaaaatta ttggtaccat caatgggatc aatgacccaa
    49201 accttgccct cttgaaccga ggctcgcaga caaccttctt cagcacaaat cttatcctca
    49261 ggataacggg acaaaatctc accaaccaag agttcctgaa cttctttgtc cagtctggtc
    49321 accaaatctg ttggagagga cttggtttca acacgcaagt cttcctgcat atggtcaaga
    49381 atgtactgac ctgctttctt aacaagctct ttagcaaatt caaatttact ttccaagaga
    49441 aatctttcct tccccttttt ctttggcagc ctgaactgct cggtaaagtg aatagccact
    49501 aaccgtttca aattctcgtc ccaaacgttt ctcttcgctc ttgcttggca cgaccgcttt
    49561 gaatccctta taggagtcca gtaacttttt agcctctact ttgccttcat aggcagcttc
    49621 aacatcatta aaaaaagaaa gcactgaagc aagttcttca gtgctccacg acaaatctag
    49681 tgggtaacta tactgtttgt tcattaacta ataccagctc tcattcttgc ttcttttagt
    49741 tcttgcttac gataactacg agggagaaaa gcacgaatct catcttcatt aaaaccgatt
    49801 tgcatacgct tggcatcaat aataattgga cgacgcaaaa gactaggata ctgctcaatc
    49861 aaatgaagca attccgatac cgaaatactc tctacatcaa tattcaattt ttgaaaaatt
    49921 tttgaacgag ttgaaatgat gtcatcagta ccattttcgg tcaaggaaag gatgtgttgc
    49981 aattcttttc ttgttaaagg actggtcata atattgtgtt ccacaaaggg aaccttatgt
    50041 ttttctaacc aggccttagc cttacgacat gatgtacagc tcggtgatag aaatagtgta
    50101 atcatgcttt tctcttctta tctatacttt gctacttcta ttatacaaaa aaataaagcg
    50161 cttgactagg gatttttaga aaaaaagcct attttttcaa gaaaaatagg ctgtttgcga
    50221 acgattgaca caattggatt tggttaattc actcttaacg atggttttaa acgatatata
    50281 tttttatata tgcaaattaa aaacatcttt catttcactt cctacgactt ttcagacaca
    50341 gatagccaaa gaagctttca tagagggcaa aaaagaggag gaaggcatga agaaagaagg
    50401 tctctggcaa aatcataata acaggatcct tggctggatc aaaaagccag gtatcatctc
    50461 ccacaaagag aatttgatgg aaaagagtaa agaattggtc aaaaccaatc aaaactcccc
    50521 caagtccaat catcacaggt aagactacta gagtcaggag actttttcga taaagagaca
    50581 aaaagtcctt tttcacaatc ctattgacaa agacatagaa acttggcagt gtcactagag
    50641 ctactagctg aaccaaatga aagagattct tgaccactgc gaaatggtgc agaccagctg
    50701 ctgacgaacg aaaatcaggc atctgtaaga cctgactaaa aggattggtc agataattca
    50761 tcaagatatg aaaattgtat tgaatggttt ctggttttag atagactcga ttcgttaagt
    50821 ttagccactg aatctccata ggatagaaaa tccaagccag ataaatggtc agaaggattg
    50881 agagggagag gagaaagagc atagagcccc aaaagatcaa tttagttttc atcaaaatcc
    50941 cactccgcaa ggctagaaac cacatgtgtc ggtgcgattg gcaggccagc tacttcttct
    51001 gccttagtaa aacctgtcgt caccaagagc gttggaatgt cattgtcaat cccagcccga
    51061 atatcagtca aataattgtc cccaaccatg attaactctt cacgttccaa acctaagtgc
    51121 tcaaccgcct tgtccataat gatggcattt ggttttccga tataaaccgg cttcactcgt
    51181 gtcgctactt caagcagcgt aatcagtgag ccagcacctg gcaaaagacc gcgttccgtc
    51241 gggatgttga ggtcaggatt ggttccgata aaatgggcac ccttttgaat agcaagagtt
    51301 gctgtggcaa atttttcata gtcgacttgc caatccagac caactaccac gtaggcaggt
    51361 ttttccttgt cttccacata accagccgcc ttgatggctt ccttgagtcc tgcttctccg
    51421 acgacataga cggtcttttc aagccccaaa tcattcatat agtcgatggt tgccaaagtc
    51481 gctgtgtaga cagtcgatag gggcgtatcg atattaaaat tctgagccaa catctcctta
    51541 acactctctg gagtgcgggt tgtattgttg gttacaaaga gatagggaat gtcccgcttt
    51601 tgcaattcat gaacaaaagt ctctccagca gggattcggt ctttcccctt ataaatggtt
    51661 ccgtctaaat caattaaata gcctttatat ttcatctatt tctccctaag ccttttttat
    51721 ttcttgccaa gtaatgattg cttgggcatt gataacccca tcacttgtaa tttcatgctt
    51781 gctttccagt ccagtccgtt caacagccga tgtaatcacc ccacctggtc gaacttcctt
    51841 gacatacttg aggttgattt tcttgggaat atagtgggtc aaaaaatccg ctcccatgac
    51901 ctcaaaaatc cagtccaagt atttactgtt attgacatga ccattcatat ccaagtcgta
    51961 aaaacgaaca tggtaatcct tgctgatcgg ttcttccaag gactcatact tcggtccacg
    52021 gataagtttt ttatcaaaat cagactggta aggagccaca atctcaggtt caacaacatg
    52081 gacttttcga ctgtcgcggt ccatgagaac aaaggtcgcc atcatgtgga tgagctcctg
    52141 ctccgcttca ttataaatag taaagcgacg gtagcaaaaa agtcgattgt agctcaaggc
    52201 ttccgtttcg atggtaattt cttccgcaaa acgaggcaaa cgaaccacct caatatcata
    52261 ttctacgata atccagacca gattatattc ttccaaaatg gccttatcac taactcccag
    52321 tgcaatcgac tgcatccctg aaacttgcag tgacagcaaa atcacatctg gaagtttgat
    52381 atgaccgttc atatcagcca tatcaaaagg aattttcatt ttcatttgat aagttaagcc
    52441 catgatccta ctccaaaata aatcgttctg ctacagtatc tcccaaaaag agacctctct
    52501 ttgtcatgcg aacgtggtca ccctcaatct gcatgaggcc ttgttgaacc aaatctctga
    52561 caatttctcc ataaagtcca gcaaaagact gtccaaattt ttcctcaaat cgcgccatgg
    52621 aaaccccgga tttcttgcgg agtcccaaga acatttcttc ttccatttgc tccttttgac
    52681 tcaggtgatc ttctgtaata caagcattgc cttcctcaac cgcactgaga taatgacgaa
    52741 tgggaccatg atttttatag cgtactccat tgacataacc agatgcccct gcaccaatac
    52801 catagtattc agcattgtcc cagtacatga gattgtgacg actttcaaag ccgggtttgg
    52861 agaaattaga aatctcataa tgctcaaaac ccgctcgctc cagctctgca atgatgtact
    52921 caaacatctc cgcttctagt tcctccttag gcagaggcaa tttcccacgt cgcatccggt
    52981 tcataaagac cgtatggttt tctaaaatca aactatacaa actcatgtgg ggaatatcca
    53041 gtccaatggc tttagccaca ttttccttta cttgctccat ggtctgacca ggcagagcat
    53101 aaatcaaatc aatggagata ttgtcaaaac cagccagttt caggcgatcg atattttcat
    53161 aaatatcctt ctccaaatga ctgcgcccaa tttttttcaa catcttatca tcaaaggtct
    53221 gaacacctag cgaaacacga ttgacagccg aatttttcaa aacagctatc ttatccgcat
    53281 ccaaatcgcc tggattggct tcaatggtca actcttccaa gacagacaag tccaagtttt
    53341 tagtcaagcc attcagtaac acctccagtt gcggagccga cagggctgtc ggtgttccac
    53401 caccgatata aagggttgac aacttttcaa tatcataaga acgaaactct tccagcagat
    53461 gctctaaata gctgtcgact ggctgatttt tgatgaagac ctttgaaaaa tcacaataat
    53521 aacaaatctg ggtacaaaat gggatgtgca cataggctga cgttggtttt ttctgcatag
    53581 taattattat accacaaaga ctagattcca gataaaaatc accatcccca gatacatagt
    53641 ccgtccggag atggtgatgg tttattcttc tgttatatca atcacaatct cttctgagtc
    53701 atcaagagct tcggcttttt cttgccattg ctccttgaga ttatttaatt gattttttga
    53761 tgcttctgtc gcttgaaaag cataggattt aacttgagca agtatactgt ccacagtgat
    53821 ttcacctgac tcaatctgtt cttttgtttt cagaacaaaa tctgtagcct gctccttaac
    53881 ttctgtcagt ttttcacaga cttgctcctt ggcatactcc ggatcttctc tcaaatcatc
    53941 tagaaaatct tgagcctgac tgcaaacttg tttgccctta tcacttgtta aaaacaaggc
    54001 aagagctgca cctgaaacgg ttcccaaaag gattgaggat aatttaccca taaggattct
    54061 ccttttttat tttttgaaaa atttacttgc aagacgaaga gctgacagac ttgcaccagt
    54121 cttgagtgtt tttgaaccag ctgatgaagc tttcttgctc aagacacgcg catggtcatt
    54181 gaggtctgaa acagatagag ataaatctgc aacagcactg aagagtggat caatcgtagc
    54241 caccttgaca ttgatatcat ctgccaagac attgacctta gccaacaact cattggtgtg
    54301 atgcaaggtc acatccacat ctgaagtcaa ggttttaatc gtcttttctg tttcatcgat
    54361 gacacgacca agcttttgta cagtaatgat cagatagacc aaaaagacaa tcaaagctag
    54421 ggcaacaaga atatatgcaa cttctaacat ttagttttcc tcctctgtaa tatagtaagg
    54481 ggccttcttt cgattttgat aaataacgat cattataccg agaccgataa ggacaactga
    54541 cagccattgg gacactcgaa gtccgaagaa catgagacta tctgttcgca taccttcgat
    54601 gaccatacga ccgaaaccat accaaatcaa gtaaaaggcc gtgatatgac ctcgtctgag
    54661 actcttccat ttccgtctaa aaatcagaat caaggcaaag ccaagcagat tccatagaga
    54721 ctcataaagg aaagtcggtt gacggtagct cccctcaata tacatctggt cacggataaa
    54781 gccaggtaga taatccagat tatccactgt tgcaccataa gcttcttggt taaagaaatt
    54841 accccaacgc cccaaacttt gagcaatcat aacgctaggc gccgcaatat ctagaaaatc
    54901 ccaagtattg atgagtttac ggtcagcaaa gatatagagc acaagagccc cagttatcaa
    54961 accaccgtaa atggccaaac caccattcca aatggcaaaa atctctccta aattctgact
    55021 atagtaatca aatcggaaaa taacatagta gagacgagct cctaaaatag ccaagggaaa
    55081 agctactaag ataaaatcta aaatatcgtc tggtatgatc ttctttctag gtgcttcttt
    55141 catggtcaaa taaaccgcaa gaatcaagcc tgtcacaata cataaggcat accaacgaat
    55201 ggctaggggt cctagttgaa tagcaattgg atcaagcatt ttgcacctca tttcgagcga
    55261 tgagacttgt cagtcgttcg tcgaacaaac gggtcgcatc aaagcccatt tccttggcac
    55321 gataattcat ggcagctgcc tcaatcacaa cagagatatt acgacctgtt ttaactggaa
    55381 tacgaatacg aggaatggct acgccagaaa cttcaagttc ctctgcattg tttccaagac
    55441 gatcaaaggt cttatgtgta tcgtaatttt ccaaatagac agcaagctga acctgtgaag
    55501 aatccttgac agcactcgca ccgtagagac tcataacatc gataatacca accccacgaa
    55561 tttcaatcaa gtgtttcaaa atttcagctg gttcacccca gagagtaatc tcatccttgg
    55621 caaagatatc gacacggtca tcggctacca aacggtgacc acgtttgaca agctcaagac
    55681 ctgtctcgct cttaccaatt ccactatctc cctgaatcaa gacgcccatc ccataaatat
    55741 ccatcaagac accgtgcaca ctggtacgtt ctgccaaacg agaatccaga tagctagata
    55801 actctccaga taaacgactg gtagctgcac ggctggttaa aatagcaatc ttacattctc
    55861 tagcagcctt taacatctcc tctggaacca ccaaaccacg ggcaacaatg actgctggtg
    55921 tctcaggtag aaacattttt ttcaaaactt cataacggct gttggaaggc atgctgatca
    55981 gataagacca ctccttcatc cccaaaagtt gaatccgctc tggtgtatag tagtcaaaat
    56041 agcctgtcat ttcaagacca ggtcgcgtaa tatccgctgt attgatttcc ttttcaagca
    56101 attctggttc accatagaca atgtctagtc taagcttttc aatcacttct tttactaaaa
    56161 ccgacatcat ttcctccttc aaatgagttc ttctctctat tatatcaaat tgtaggagga
    56221 agtttcagat ttttgcaggc tttggagtat ttatttaaaa gaaaaaggac tagatttctc
    56281 tagcctttca tttcaattag aattttttac gtttacgagc tacttctgat ttacgtttac
    56341 gttttacaga aggtttttca tagaattcac gtttgcgtgt ttcttgaaga gtaccagctt
    56401 tagtaaccgc acgtttgaaa cggcgaagtg cgtcgtcaag agattcattc ttacgtacta
    56461 ctgttttaga catttttttc actcccttca agttcaatat ctatttcatt ctacacgtaa
    56521 aaggaataat tgtcaagcaa aaatgcggtt taattttgat tttttcttcc atttatacaa
    56581 gagttgaaag cgttcaatag aacattgctt ttttattttt cgagtaagct aagcgcttca
    56641 gcatctgcga tgatggttac atcagggtga ttttgaaggc tacttgcagg taggttctca
    56701 gtcactgggc cagatactgt tccggcaatg gcttctgctt tcgactcacc gtaagcaaaa
    56761 agaataatag acttggcatc caaaatgttt ttaatcccca ttgaaatagc ttgggttggg
    56821 acgtcttcaa tcttggcaaa gaagcgtgca ttggcttcga tagtagactg gtcaagttct
    56881 actagatgcg tttgactgtc aaatggagta ccaggctcat taaagccgat atgcccattg
    56941 cgaccgattc ccaagatttg gaggtcaact ggatggtcag ccaaaatttg gttgtagcgt
    57001 tcaacttcag cttcagcatt gtccttaaca ccacgaggca agaaactttc tttaaatggt
    57061 ttttggttga acaagttttc ttgcatgaag taacgataag actgtggatt gtccccatca
    57121 aggcccacat actcatcaag gttgacactg gttagatttg aaaaatcaag gtcactctca
    57181 acaatttcct tgtaaaattc aagtgggcta cttcctgtcg caagtcctag agtttgagct
    57241 ccattagcca atttttcctt caaaatctca aaagcaactt ttccaccttg aacttggttt
    57301 tcaactttaa taactttcat cttttcatcc tccatttctg tctatattta ttatatggta
    57361 tagaccaatt tttgtcaagt gaaaacgatt taatttctaa aaaaaagagc gtccaaactt
    57421 gaaacgtgtt ataatggata ggattagaac ttagaaagaa tgaacaaata tatgaataca
    57481 gctgattttg atttccactt gccagaggaa ttgattgccc aaacgcccct tgaaaaacgt
    57541 gatgcctcca aactcctcat cgtcaaccgt gagacaggag aaatgcaaga taaacatttc
    57601 cactctatta ttgatatgct ggaatctggt gatgcccttg tcatgaacga cacccgagtt
    57661 ctccctgccc gcctctatgg tcaaaaagtg gagacaggag gtcatgtgga acttctcctc
    57721 cttaagaaca ctagtggaga cgagtgggaa gttctggcta aacctgccaa acgcctcaag
    57781 gtcggtactc gtatcagctt tggtgatggc cgcctcagcg ctgtcgttac agaagaattg
    57841 acccacgggg gacgcattgt ccgctttgaa taccaaggaa ttttcctaga agtcttggaa
    57901 agtctgggag aaatgcctct gccaccttat atccacgaaa aattagatga ccgtgaacgt
    57961 tatcaaaccg tctacgccaa ggaaagcggc tctgctgcag caccgactgc tggtcttcac
    58021 ttcaccaaag aactgctggc agaaatccaa gctaagggtg ttcatctagt ctatctgact
    58081 ctccatgtcg gactcggaac ctttagacct gtttctgtgg ataatctgga cgaacacgaa
    58141 atgcactcag agttctatca actttctgag gaagctgctg ccacccttcg ctctgtcaaa
    58201 aaaaatggtg gtcgtgtcat cgctgtcgga accacttcta tccgcacctt ggaaactatt
    58261 ggttccaagt ttgatgggca aatccaagca gattctggtt ggaccaatat ctttatcaaa
    58321 cctgggtatg agtggaaggt cgtggatgcc ttctcaacca acttccacct gccaaaatca
    58381 actctggtca tgttggtttc tgcctttgca ggccgtgaat tagtcttaga tgcctaccac
    58441 cattccatcc aagaacacta ccgcttcttc agttttggtg acgccatgtt tatttattga
    58501 gaaagaattt ctctaaatct tctaatacca ataaatcgct aagatattat ttcaaagaac
    58561 atctacaatt gaaactctag ctagctgtgg aagaggccta gtacattgaa attaaaatgc
    58621 ttccccctag cttcgaaaat attgccatag attgcgttga ctctccaaat tgattcatct
    58681 atattttatt tcagcttcct atattttctt cgctgtttgt aaatcaaaat gcaagacaca
    58741 tgagtagcac catatttgtt actcttatct gtcctctcaa gagactatta tgagttattt
    58801 cagaatcatt cactactttg accctgactc tccttagtct caaaatcaaa gacttatact
    58861 cttcaaaaat ctcttcaaac cgcgtcaacg tcaccttgga ttatatatgt gactgacttc
    58921 gtcagttcta tctacaacct caaagcagta ctttgagcaa cctgcgacta gttttctagt
    58981 ttgctctttg attttcattg agtattaaac aaaaagtgaa caaatctgaa ttctaatgta
    59041 cagaagacta ggcttgttca cttttttata gtcgctataa gatgacctta tctatagctt
    59101 tttatatata attatatatt cagacatact attatcaatt ttgtcgcagg gaggaatctg
    59161 ttaacgcacc cattcaccat tatcattgac tctatagcca tctatacttg tattgaccgc
    59221 taactcaccc gatgcattta cataatacca tttaccacca acttggaacc attgattgac
    59281 tttcatagaa ccgttgctgt tgaggtagta ccatgaacca ttaacttgta cccaacctgt
    59341 tgccatggaa ccatcagtat tataaaaata ccacatacca ttttcttgtt tccagtctgt
    59401 tgttggagca actgctttag ctggttctac tgctacatct gttccttggt tagatgtaac
    59461 agatacagga tacgaaggaa tagatgattg ctcaggaaca acaacttttt caggttctct
    59521 cgtccctctc cttatacgtc tttttaccat ctctttagta atttgacgag aagtagtttc
    59581 ttcaattgtt ccatcacgtt catctacagc atagattgta gtaagagtaa tttaccaatt
    59641 tctcctactt cttctacttc ttgactttta tcaagagttg ggccatcgag atattctgtt
    59701 tcgattggaa tttcttggac aagaacttgg ggcttggttc tttttttaac aactcttgtt
    59761 tgagagtctt ttttttgact taaagtactc tcagttactt gtccactctt tccatctaca
    59821 ttataagtta tcgttgtaac tgttttccca ttctttccta gagtaatctc ttgctcctgt
    59881 cctgcagaaa ggtcattgtc tgcttcatat ttagtagcaa atggaacaag aacttcttca
    59941 accttgcttt tagctggaac tttgataact gtatccgtgg cttcttttct atcaacagta
    60001 acctgttcgg taacataacc agtctctgga ttaacatcgt aggtccttgt cgtagttaca
    60061 tagccatcct ctccatcaat tgtaacagga ttttcactac ggtcttttgt ttcatctttt
    60121 tcataacgaa ttcgcgtact tgaaattttc ttggttacta ccttaggttt agtcgctact
    60181 tttacaataa tatccccatt gtcagcgtca tcatactcta ttccctcttc tttatctcta
    60241 gtatcatctc tgacatattg aatcccatca gcagcatgaa caaaacttgt attcagattc
    60301 ctcctaaaaa taaagttagc ccgattaccg cagaaccaaa aatctttccg agtttacgta
    60361 ttgcatagcg cttattagta ttagattttg ccattacatc ctacttctag tatagcatct
    60421 tttctatcaa acgttaaaca atatacttta tatataaaaa tagacttaga atgatatatt
    60481 gattattgaa ctaacacttt aactatatcg taatcaatct catatataaa ggattgcaga
    60541 catcttatct aaatacatgc taatatattt agatacaaac attccaactt gataactttc
    60601 actcatcttt catcattcct tatacaacta tgcagt
//
LOCUS       DAVLZS010000008        59007 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLZS010000008 DAVLZS010000000
VERSION     DAVLZS010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.008"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(381..1361)
                     /locus_tag="VYO88_000486"
     CDS             complement(381..1361)
                     /locus_tag="VYO88_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV1718647.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1677..3692)
                     /gene="recG"
                     /locus_tag="VYO88_000487"
     CDS             complement(1677..3692)
                     /gene="recG"
                     /locus_tag="VYO88_000487"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1718648.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3711..4814)
                     /locus_tag="VYO88_000488"
     CDS             complement(3711..4814)
                     /locus_tag="VYO88_000488"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1718649.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREVSEVEQAQDLLQKHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4804..5172)
                     /locus_tag="VYO88_000489"
     CDS             complement(4804..5172)
                     /locus_tag="VYO88_000489"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1718650.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5211..6242)
                     /locus_tag="VYO88_000490"
     CDS             complement(5211..6242)
                     /locus_tag="VYO88_000490"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1718651.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYATLTK"
     gene            complement(6244..7275)
                     /locus_tag="VYO88_000491"
     CDS             complement(6244..7275)
                     /locus_tag="VYO88_000491"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1718652.1"
                     /translation="MVFAAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7356..9869)
                     /gene="secA"
                     /locus_tag="VYO88_000492"
     CDS             complement(7356..9869)
                     /gene="secA"
                     /locus_tag="VYO88_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1718653.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10015..10302)
                     /locus_tag="VYO88_000493"
     CDS             complement(10015..10302)
                     /locus_tag="VYO88_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718654.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLVFGILSILMAFLSKKVSLFVFGLICCLSLWINLFILFALLPIFGN"
     gene            complement(10330..10962)
                     /locus_tag="VYO88_000494"
     CDS             complement(10330..10962)
                     /locus_tag="VYO88_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1718655.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10966..11607)
                     /locus_tag="VYO88_000495"
     CDS             complement(10966..11607)
                     /locus_tag="VYO88_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718656.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(11600..12391)
                     /locus_tag="VYO88_000496"
     CDS             complement(11600..12391)
                     /locus_tag="VYO88_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718657.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSIFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12576..12911)
                     /locus_tag="VYO88_000497"
     CDS             complement(12576..12911)
                     /locus_tag="VYO88_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718658.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGGRH"
     gene            complement(13052..13387)
                     /locus_tag="VYO88_000498"
     CDS             complement(13052..13387)
                     /locus_tag="VYO88_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718659.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13478..14788)
                     /gene="der"
                     /locus_tag="VYO88_000499"
     CDS             complement(13478..14788)
                     /gene="der"
                     /locus_tag="VYO88_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1718660.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14802..15515)
                     /locus_tag="VYO88_000500"
     CDS             complement(14802..15515)
                     /locus_tag="VYO88_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1718661.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15512..16408)
                     /gene="dnaI"
                     /locus_tag="VYO88_000501"
     CDS             complement(15512..16408)
                     /gene="dnaI"
                     /locus_tag="VYO88_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1718662.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16409..17578)
                     /locus_tag="VYO88_000502"
     CDS             complement(16409..17578)
                     /locus_tag="VYO88_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1718663.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17579..18052)
                     /gene="nrdR"
                     /locus_tag="VYO88_000503"
     CDS             complement(17579..18052)
                     /gene="nrdR"
                     /locus_tag="VYO88_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1718664.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18192..18557
                     /locus_tag="VYO88_000504"
     CDS             18192..18557
                     /locus_tag="VYO88_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1718665.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18562..19257
                     /locus_tag="VYO88_000505"
     CDS             18562..19257
                     /locus_tag="VYO88_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718666.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19274..20041
                     /locus_tag="VYO88_000506"
     CDS             19274..20041
                     /locus_tag="VYO88_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718667.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20394..21593)
                     /locus_tag="VYO88_000507"
     CDS             complement(20394..21593)
                     /locus_tag="VYO88_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1718668.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMSKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21590..22483)
                     /locus_tag="VYO88_000508"
     CDS             complement(21590..22483)
                     /locus_tag="VYO88_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718669.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22599..22679
                     /locus_tag="VYO88_000509"
                     /pseudo
     CDS             22599..22679
                     /locus_tag="VYO88_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            23189..23377
                     /locus_tag="VYO88_000510"
                     /pseudo
     CDS             23189..23377
                     /locus_tag="VYO88_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23792..24409
                     /locus_tag="VYO88_000511"
     CDS             23792..24409
                     /locus_tag="VYO88_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1718670.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24729..25616)
                     /locus_tag="VYO88_000512"
     CDS             complement(24729..25616)
                     /locus_tag="VYO88_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1718671.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25765..27648)
                     /locus_tag="VYO88_000513"
     CDS             complement(25765..27648)
                     /locus_tag="VYO88_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1718672.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVREVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFAFTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFETKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            28023..29477
                     /locus_tag="VYO88_000514"
     CDS             28023..29477
                     /locus_tag="VYO88_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1718673.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRTSEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29458..30423
                     /locus_tag="VYO88_000515"
     CDS             29458..30423
                     /locus_tag="VYO88_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1718674.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30459..31733)
                     /locus_tag="VYO88_000516"
     CDS             complement(30459..31733)
                     /locus_tag="VYO88_000516"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1718675.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQIANPKLAQEKIASKKAELLELANQAYPSIVKRGGGASDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(31733..32905)
                     /locus_tag="VYO88_000517"
     CDS             complement(31733..32905)
                     /locus_tag="VYO88_000517"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1718676.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     ASLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(33036..33284)
                     /locus_tag="VYO88_000518"
     CDS             complement(33036..33284)
                     /locus_tag="VYO88_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718677.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(33352..33976)
                     /locus_tag="VYO88_000519"
                     /pseudo
     CDS             complement(33352..33976)
                     /locus_tag="VYO88_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(34038..34487)
                     /locus_tag="VYO88_000520"
     CDS             complement(34038..34487)
                     /locus_tag="VYO88_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1718678.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(34489..35247)
                     /locus_tag="VYO88_000521"
     CDS             complement(34489..35247)
                     /locus_tag="VYO88_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1718679.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(35362..37341)
                     /gene="pknB"
                     /locus_tag="VYO88_000522"
     CDS             complement(35362..37341)
                     /gene="pknB"
                     /locus_tag="VYO88_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1718680.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIILTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(37338..38078)
                     /locus_tag="VYO88_000523"
     CDS             complement(37338..38078)
                     /locus_tag="VYO88_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1718681.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(38093..39406)
                     /gene="rsmB"
                     /locus_tag="VYO88_000524"
     CDS             complement(38093..39406)
                     /gene="rsmB"
                     /locus_tag="VYO88_000524"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1718682.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVALKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(39399..40334)
                     /locus_tag="VYO88_000525"
     CDS             complement(39399..40334)
                     /locus_tag="VYO88_000525"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1718683.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(40347..42743)
                     /locus_tag="VYO88_000526"
     CDS             complement(40347..42743)
                     /locus_tag="VYO88_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1718684.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(42809..43123)
                     /locus_tag="VYO88_000527"
     CDS             complement(42809..43123)
                     /locus_tag="VYO88_000527"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1718685.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(43148..43774)
                     /gene="gmk"
                     /locus_tag="VYO88_000528"
     CDS             complement(43148..43774)
                     /gene="gmk"
                     /locus_tag="VYO88_000528"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1718686.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(43904..45517)
                     /locus_tag="VYO88_000529"
     CDS             complement(43904..45517)
                     /locus_tag="VYO88_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1718687.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(45708..45962)
                     /locus_tag="VYO88_000530"
     CDS             complement(45708..45962)
                     /locus_tag="VYO88_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV1718688.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(45966..46220)
                     /locus_tag="VYO88_000531"
     CDS             complement(45966..46220)
                     /locus_tag="VYO88_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1718689.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(46458..47555)
                     /locus_tag="VYO88_000532"
     CDS             complement(46458..47555)
                     /locus_tag="VYO88_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1718690.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLEQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRTQMALENGADLVVELPFLVSVQAADFFGQGAMDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(47565..48311)
                     /locus_tag="VYO88_000533"
     CDS             complement(47565..48311)
                     /locus_tag="VYO88_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1718691.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFVEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(48414..48767)
                     /gene="rsfS"
                     /locus_tag="VYO88_000534"
     CDS             complement(48414..48767)
                     /gene="rsfS"
                     /locus_tag="VYO88_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1718692.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(48780..49280)
                     /locus_tag="VYO88_000535"
     CDS             complement(48780..49280)
                     /locus_tag="VYO88_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1718693.1"
                     /translation="MKMAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKIAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(49281..49874)
                     /gene="yqeK"
                     /locus_tag="VYO88_000536"
     CDS             complement(49281..49874)
                     /gene="yqeK"
                     /locus_tag="VYO88_000536"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1718694.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVVYVADYIEHNRSFPGVDVAREVASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(49874..50503)
                     /locus_tag="VYO88_000537"
     CDS             complement(49874..50503)
                     /locus_tag="VYO88_000537"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1718695.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(50555..50866)
                     /gene="yhbY"
                     /locus_tag="VYO88_000538"
     CDS             complement(50555..50866)
                     /gene="yhbY"
                     /locus_tag="VYO88_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1718696.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(51080..52186)
                     /gene="yqeH"
                     /locus_tag="VYO88_000539"
     CDS             complement(51080..52186)
                     /gene="yqeH"
                     /locus_tag="VYO88_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1718697.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKYAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(52189..52779)
                     /locus_tag="VYO88_000540"
     CDS             complement(52189..52779)
                     /locus_tag="VYO88_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1718698.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(52731..53639)
                     /locus_tag="VYO88_000541"
     CDS             complement(52731..53639)
                     /locus_tag="VYO88_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1718699.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(53696..54256)
                     /locus_tag="VYO88_000542"
     CDS             complement(53696..54256)
                     /locus_tag="VYO88_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV1718700.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            54395..55604
                     /gene="sstT"
                     /locus_tag="VYO88_000543"
                     /pseudo
     CDS             54395..55604
                     /gene="sstT"
                     /locus_tag="VYO88_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            55672..56625
                     /locus_tag="VYO88_000544"
     CDS             55672..56625
                     /locus_tag="VYO88_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1718701.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            56768..57148
                     /locus_tag="VYO88_000545"
     CDS             56768..57148
                     /locus_tag="VYO88_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1718702.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETVAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKILASLQKTVEESLEAGLDFLI"
     gene            57247..57468
                     /locus_tag="VYO88_000546"
     CDS             57247..57468
                     /locus_tag="VYO88_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1718703.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            57485..57799
                     /gene="trxA"
                     /locus_tag="VYO88_000547"
     CDS             57485..57799
                     /gene="trxA"
                     /locus_tag="VYO88_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1718704.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            58106..58639
                     /gene="queF"
                     /locus_tag="VYO88_000548"
     CDS             58106..58639
                     /gene="queF"
                     /locus_tag="VYO88_000548"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV1718705.1"
                     /translation="MKRQLALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            58701..>59007
                     /locus_tag="VYO88_000549"
     CDS             58701..>59007
                     /locus_tag="VYO88_000549"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718706.1"
                     /translation="MFEVVDKTDEVSSKHCFEVADRTDKVSLKHCFEVADRTDEVSLK
                     HCFEVADRTDEVSLKHCFEVVDETDEVSLKHCFEVADRTDEVSLKHCFEVADRTDEVS
                     "
BASE COUNT        16794 a        13408 c        11359 g        17446 t
ORIGIN      
        1 aacatatata cggcaaggcg aagctgacgt ggtttgaaga gatttttgaa aagtattaac
       61 acctacagac aagcctaacg atagcaagaa ctaccctact cgatagatat cggcttttgc
      121 tttctgaaaa aaattatttt aagcaatttg acaaatctag caacaaaaaa ttctataaat
      181 ataatagatt gaaactagaa tagtacacat ctacttctaa aacattgtta gaaatcgatt
      241 tgactgtcct gatcgatttg tcctgttctt gtttcatttt actatatttc catgataaaa
      301 cgcatagtat caagtttttt taatcccctg atactatgcg tgtttgtaat ttttaagatt
      361 ttgtgcttag agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc
      421 cagttgtaga cttggtcatt gacaaataca ttcatggctt cgtgagcata ctcaggcatg
      481 atacgatagg ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag
      541 caaacatcgt cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga
      601 tttttgacat cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg
      661 tcgtgaaact tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatctca
      721 atcacccgtc tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga
      781 ttgagcgctg ctgcaactag agctagagcc cctccttgtg aggcaccata gctagaaaga
      841 cgcttctcat caacctgaga cagactagca acaatttcga ccaactggta aatatccaga
      901 taaacatcct tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc
      961 ttcacggtat ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc
     1021 acatccatgg aaacaacacc gtaaccagct acggtgaagc ccagcatgtc ggcccagtcc
     1081 cagccacgtc ccatataacc atgaaaatgg aagattagtg gaaccttctc ctcactcttt
     1141 ggaagaacaa tgcgtgcata gacctttcct tccttgcttc cttcaaatgt taactcatag
     1201 cacttgactt gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aggtgtggaa
     1261 acatttttca cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct
     1321 ctataggtct taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt
     1381 gtaatcgtta ccacaactgt agcatatcta tgtaatcaat gcaagaaaga aggataaata
     1441 gaaagtgaat ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga
     1501 aaaagagcat ttcgctctct cttctgttta tactagtttt ttgcttcctt cttttggaaa
     1561 gtggtttggt aatttacttt aatcgttact gtcatatgag agtcctcgtt tctttttgat
     1621 gactttagta taagagccaa acctaaaaac tagcttaagt tttccttaga gaaagcttaa
     1681 tccagatgtt ctttcttttc cagatgaagg gcaatcatgc gccactctgg atcttcttgc
     1741 caagcttcta tagaactaat gtagctagca acctttcttg cttcttctaa aatcggaaaa
     1801 tcttcgataa tatcagccac ttggaactct ggaagtcctg actgtctggt tccaaaaatc
     1861 tcaccagaac cacgcatttt caaatcttcc tccgcaagga caaatccatt ggtcgtttct
     1921 gtcatgatgc gcatgcggtc tttcccagaa tccgtcttgg gattggcaac gagaacagcg
     1981 taggactgct tgtccccccg accgacacga cctctaagct ggtgaagttg actgagaccg
     2041 aagcgatcgg catccatgat aatcatgaca gtcgcattgg gaacgttgac cccaacctca
     2101 ataaccgtcg tcgaaaccag aatatccgtc tttctctcct tgaaatcctg catgatctgg
     2161 tctttttcgt cactcttcat cctaccatgt agaagagcca cctctgcctt gcctgcaaaa
     2221 tgagtcgtca actcctctga taaggcaatg gcatttttca aatctagagc ttctgattct
     2281 tcaatcaaag gagagatgac ataggcttgg gaaccttttt gaatttcccc ctctaaccaa
     2341 gtcaagacct gaggtagttg ctcatgtttg atccagcgcg tcacaatagg cttccgacct
     2401 gctggcatct ggtcgataat ggaaacatcc atatctccaa aggctgtgat ggcaagcgtc
     2461 cgtggaatgg gagtcgccgt catcatgagg acatctggat tgtcaccttt ttcccgtaaa
     2521 atacgccttt gccctacacc aaaacggtgc tgctcatcga taataatcaa accaagacga
     2581 gcatactcca ccccatcttg tatcagagcg tgagttccga taatcaaatc agcctcaccc
     2641 ttggcaatgg tctccaagac ctctctcttt tctgcagctt tcaaggaacc tgtcaagaga
     2701 gccagtttca aattgggaaa aaggttctgt aaactctcaa agtgttgctc tgcgaggatt
     2761 tctgttggta ccattagggc agcctgataa cctgctgtca ctgccgcaaa catggccaag
     2821 ccagcgacta ccgtttttcc actccccaca tccccttgta ggagacgatt catgtggtgg
     2881 tcggacttca tatcagttaa aatttcctgc aaactctttt cctgagcttg ggtcagggca
     2941 aaaggaagac ttactttaac tgctgtcact ttttcctgag accaattcag aaccagacca
     3001 cttccctgaa ctctattttc agacttgagc gtctgcaact gcatttggaa ataaaagagt
     3061 tcctcaaact tgatacggcg aagagcctgc ttgtattctg ccaaatcctt tggaaaatgc
     3121 atagctcgga ctgcctgaca acgggacatg agtttgtatt tgtctagtaa agactggggc
     3181 agattttctt ctatcaagag gtccagtccc tgatcaaaag ccgtcttgat gaccttaacc
     3241 agactggcct gactgattcc ctgagccaga cgatagacag gctggaggtc atcttctacc
     3301 tgagccagaa ccttcatccc agtcagacta gccttagcgc ggtcccattt tccaaagaca
     3361 gcaagggttg ctcccaactc tattttatca gccagatagg gctggttaaa gaaattcacc
     3421 gcaaaaacga cctctccctg cttgagacta aaacgcaggc gattgcgctt gaaaccataa
     3481 tactggacac tagcaggagt cactacctga ccagaaagaa ctgccttctc accgtcttct
     3541 agttccagca cctgcttggt tttgaagtct tcataacgga aaggaaagta gagcaagaga
     3601 tcttgcaagt tttcaattcc tagtttggcg tatttttctg ctgactttgg tcccacacca
     3661 ggcaagacat gcaagggttg atgtagattc atgctccact cctttctttt ctaataatat
     3721 tctctcggaa tacggtcgct gaggaggcaa accacctcat agttaatggt gacgcggtag
     3781 gtcgctacct gagttgcagt gatttcctta tccccattgg agccaatcaa ggttaccttg
     3841 gttcctagcg gataaagctt aggcaatcga atagtgattt ggtccatcga aaccctgccg
     3901 acaattgggc aagcttggcc atctaccaag acagagaaat tttgcatgtc tcttgtccat
     3961 ccatctgcat acccgattgg cacggtcgcg atgacttgct cgctatccgc ttgataagtt
     4021 gctccatagc ccatgcaagc tccagctgga actgtcttga catgaaccag agcagactcc
     4081 aaggtcaagg ccggtatcaa atcataaggc aaatccaaga ccgctccact tggattgagg
     4141 ccatacatgg catctcccat acgaaccgca ttgaaaatag tctctacatg ccaaagagtc
     4201 gttgcagaat tgctagcatg aaccagctct ggaacttcct tcatactagc taaaatagtt
     4261 ttaaaccgtt ctaactgggc attaaaatag tcatctgatt cctcatcagc agtagcaaag
     4321 tgggtaaaga ttccttcaac acaaacaccg tgtttttgga gcaaatcttg agcctgctca
     4381 acctcactga cctctctaaa accaatccgt cccatccctg aatcaatctt gaggtggact
     4441 gtcaatccag ttaggtccac ttccttatct aagagtgctt gaatccactc cagtccagcc
     4501 actgtcaagg tgaagtcata ttctttagct agagcaacag cttcgatttc agaaactcct
     4561 aaaatgagga ttggcttgct gagtccagct tgtctgagtt caatggcttc atcgatattg
     4621 gaaacgcaaa agccatcaac atcatcttga attgccttgg caacggcaac agctccatga
     4681 ccataagcat tggccttgac cacagcccac ttgagcgttc cttgagggat atgagccccc
     4741 atttgctgaa tattttgtcg aatagctccc agatgaatca gagccttggt tggtctatgt
     4801 ggactagctt tcatgatttt cctccaaaat gacactggct gtcacaaact gatcggtgtg
     4861 gctgatagac agccaaatct ttcctgaaaa tggtgcctga ctaaaataag gcgccccacg
     4921 ttcattgttc aagacttcca aatcctgaaa accgagcttg ctaatgcccg ttcccatagc
     4981 cttggaaaag gcctccttag ccgaccagcg accagctaaa tattctattt gcctgcgtcc
     5041 tttgagactg gtgaagcgct ccatttcctg agcggtcagt acacgcttag caaatccttc
     5101 atgtcgtgta actgcgcttt ctatcgaagc caattcttcg atgtcaattc cgtgtccaac
     5161 tatcattctc atcaaaagga gttgagattc cccaactcca tccttttcac ttattttgtc
     5221 aaggtagcat agatttcttc taccaaggcc tctgtatttt cccaacctag gcaagggtca
     5281 gtaatagagc aaccaaagat ttctggttgg ttttgacgac catctgctag gtaagattca
     5341 atcataaatc ctcgaaccgt ctttttaatt ttctcattcc aatcacgatt ctgcaaggtc
     5401 tggcgaacaa ttcgaatctg ctccatatat tgcttgcctg agttatcatg gttggtgtca
     5461 atgaggataa aaggattttc aagtcccatg gtttcatagc gttcaatggc ttggagtagg
     5521 ttttcatagt agtaattcgg catataattg ccatactcgt tgactgctcc acggaggata
     5581 acatgggcca aaggattacc tgatgtctca acttcctgcc catgataaag gaaggtttgc
     5641 ttgttttgag cagcatagat ggcgttaaac ataacaccca aatttcctga ggttggattt
     5701 ttcatcccta ctggtgcatc aatcccagaa gccacaaagc ggtgctcttg gtcttccaca
     5761 gaacgagctc caacggcatg gtagctgacc aagtcatcca ccaagatcag atttgacgga
     5821 taaagcatct catctgccgt tgtcaaacca gtctctgtaa tcacgcggta gtgcaactgg
     5881 cgcacagcct gcaagccgtt aatcaggctt ggagccttag aagtatctgg ctggtgaacc
     5941 aatcctttat agccgtctcc attggtacga ggcttagcag tatacacgcg catgaccatg
     6001 aaaatcttgt ccgctacctt cttttgcaag gcggataaac ggcgagcata ttccaagacc
     6061 gcctcttcat tatcagaaga gcaaggacca atcaccaaga gaatacggtc atcttcccct
     6121 gaaataatat ctgccaattc cctgtcacgg ctttccttga gtctcaaggc ttccgcagac
     6181 aattgggttt cagccttgat gacttccata tcgatttctt gacctttttc aataaatgcc
     6241 atcttattct cctaacgttt tgtaaatttc tctgacaaga gcttctgtgt tatcccaacc
     6301 caggcaaggg tctgtgatag acttaccaaa tacttctggc tcattttgtc gaccatcttc
     6361 cagataagac tcaatcataa aaccacgaac gaactgctta attttttcat tccaagcacg
     6421 gttaatcaag gtctggcgga caattcggat ctgttcaata tactgcttac cagaattgtc
     6481 atgattggta tcaatgatga taaaaggatt ttccaagccc attttctcat actgggcaat
     6541 ggtatcaatt aaattgtcat aatagtagtt gggaatattt tttccatact cattaagagc
     6601 accacgaaga atagcgtgtg aaagcgggtt cccagttgtt tctacttctt ttcctaagaa
     6661 aaggaaactt tgtttgtttt gagcagcata aatcccatta aacatgacat tgagatttcc
     6721 agaggttgga tttttaaaac cagtagaaaa tcctgcccca cttgccacaa agcggtgttg
     6781 ctggtcttca actgaacggg caccaactgc catgtaagaa atcaaatcat ctacaagcgg
     6841 aaggttttca ggataaagca tttcatcagc agttgtcatc cctgtttctg tgatgacacg
     6901 atagtgaaga tggcgaacgg ctttgattcc attgataaga ctaggcgctt ctgtcgcgtt
     6961 aggctggtga atcaagccct tatagccatc tccgttggta cggggtttgg cagtataaac
     7021 acgcataacc ataaagatac gatctgccac ttcttcttgt aggactgcca aacgcttagc
     7081 gtattcaagg acagcttctt cgttgtcaga tgagcatggc ccgattacca agagaattcg
     7141 ctggtcttct ccacgtataa tggcttctag ctcttgatct cgctgtgatt tcctctccaa
     7201 agcctgacct tctaattttg acaaggcacg aacttcttct atatttattt tagagctttt
     7261 tgctgcaaat accataactc atctccttat aaagcaaacg gatacccagt aaaaatttac
     7321 ttttcacaag atatccgcct ctaaactatc tcattttatt gtcttttacc gtgacagttt
     7381 ttaaatttct taccagaacc acatgggcaa agttcattgc gtccaatctg gctcaaatcc
     7441 aaatcttctg gcatacttgc ttggtgagca gcgatattgc gagtcgctgt tgtactgata
     7501 tgacgttctg cctgtggtct ttcttgttca tgaatttgtg ctttcatcat caagcgtgtc
     7561 acatcaaact caatcgaacc aatcatatca ttaaacatac ggaaaccttc tgcctgatac
     7621 tcaacaacag ggttgttctg agcatagcca cgaagtccaa ccgcgttacg caattgatca
     7681 agggcatcga tatgatctgt ccacttgtta tccaccactc gtagaatcaa aactttttgg
     7741 aattctttaa ctgcttcttc atcgcgtagt tttgaaacct gactatcgta aaccttcaag
     7801 gcacgttgga aaagctcttc cttgatggcc ttatcagaca agcctgacaa gtcttccatc
     7861 gtaatagaat cttcaggaag caagttgtac ttagcaaagt tcaaaattgc ctctagtttt
     7921 tcatcttgtt tggcacgcgc atgaccatca acgacacgtt caatcgtgcg tttgatcata
     7981 gactgaattt caggtgccaa gtcacgatct gcagtgatga catcgtaacg ttgagtatag
     8041 ataatctcac gttgttcacg catgacatcg tcgtattgaa ggacttgttt acgggtatcg
     8101 tagttatttc cttcgacacg tttttgcgct gcttcaacct gacgcgtcaa catgcgagac
     8161 tcaatcgcct cttcagacat gttgagacgt tcaaagattc ccttcaagcg ttcagaacca
     8221 aaacgtttca tcaaatcatc ttcaagagat aggtagaatt gtgactcacc tggatctcct
     8281 tgacgacctg aacgtccacg aagctggtta tcgatacgac gactttcatg acgttctgta
     8341 ccaataacac aaagtcctcc aagttcacga acaccttcac caagcttgat gtcggtacca
     8401 cgacccgcca tgttggttgc gatggtaacg gcaccacgtt gaccagcatt catgatgatt
     8461 tgggcttctc tatagtggtt tttggcattc aagacttcgt gaggaacacc agctgcaacc
     8521 aatttcttag aaatgtagtc actagtttca accgctactg taccaaccaa gacaggttga
     8581 cccttttggt aacgagcctt aacgtcttcg acaaccgctt taaacttaga ttcgatactt
     8641 gcataaagaa ggtctgagtg gtcaatacgt tgaacaggac ggtttgttgg gattggaata
     8701 acacgaatgt tgtagatttc acgaaattct tcttcctcag tcttacctgt acccgtcata
     8761 ccagacaatt ttttgtacat acggaaaagg ttttggtacg tgattgaggc agatgtcttg
     8821 gtttcatcct ggattggcac accttctttg gcttcaatag cttggtgcaa tccatcagaa
     8881 taacgacgac cttccatggt acgacctgta aattggtcga caatcaagat ttcttgctct
     8941 tcgctcacca catagtcaat atcgagaagc atgatgtagt tggcacgaag ggcgttatcg
     9001 ataaagtggg tcaaagccac gttttcgatg tcatagaggt tttcaagttt gaagtagctt
     9061 tcagccctgt caatccctga atcagacaaa ccaatagtct tagactgcac atcgatgatg
     9121 tagtcatctt tgttcaaaga ttttacatag tggtctgcca tgtgatacaa ctgactggtt
     9181 tcaaccgcat tggcacctga tacaatcaaa ggtgtacgag cctcgtcaat caagatagag
     9241 tcaacctcat cgaccaaggc atagttaagc ggacgttgta ccatgttttc agcgcgaaca
     9301 accatattgt cacgaaggta gtcaaatccg atttctgagt tagttgagta agtaatatca
     9361 cactcatagg cttctttttt ctccattgga gatttggtag ccaagttaat ccctactgac
     9421 aaaccaagcc aagagtacaa ttcacccatc tcagtcgcgt cacgttctga caagtattca
     9481 ttaaccgtaa ctacgtgaac ccctttacct gaaagggcat tgaggtatac cggcatggtc
     9541 gcagtcaagg ttttcccttc ccctgtacgc atctctggca cgtcaccatg gtgaagaaca
     9601 atccccccca tgacctgaac cttataaggg aagagaccta ggacacgttt ggcaccttca
     9661 cggacaaccg caaatgcttc gtaaagcaat gaatccagtg attctccatt ttgataacgt
     9721 tccttaaatt caactgtttt tgcttttagt tggtcgtcag tcaaagcagc catttggtct
     9781 tcgtatttga aaaccttgtc agccatcttt tccagacgac ggatttctcc tttatcattt
     9841 tcgataattg tttttaaaat attagccatg tttttcctta ctttaaattc cgaatatttt
     9901 agaatgttct tttaatttta gcacaattac tgattatttt caaggaagaa tccccatttt
     9961 gaaaaggaaa aagaggctag tttccaagtt aacctctctg acttttatga tgctttaatt
    10021 gccaaaaatc ggcaaaagag caaataggat aaatagattt atccaaagag aaagacagca
    10081 aatcagtcca aaaacgaaga gactgacttt cttggataag aaggccatca aaatggacag
    10141 aataccaaaa accagcaaga ttttctgtat gatgaagatg tcaatcctta cccccagaat
    10201 cgctctatcc caagggataa agaagaaaga cagccagatc agcagaacta aaccaatata
    10261 aaccttggaa tagcgtgtaa taaatgattt tagatgtgcc ataagccatc tcctaggatt
    10321 gtatatcctt tacatttgta tatgtccatt ttcgacaact aatacatctg tacaaaggtc
    10381 tgaaatatct tccgatatgt gcgacgtcag gataaccaga ccattttctt ttttcaggta
    10441 agataaaatg acctgtttgg ttaacctcac actcttctca tccaaagcat tcataggttc
    10501 atcgagaaag agtatagaag gagaggaaat aaaggcttga atcaaggcca ttttttgctt
    10561 tgttcccaag gataaatgcc ggtattcaac gtcttcaaat tcctgtaaat catagtattg
    10621 aatccaatag gcaattcttt tttccgtaac tttagatgaa aaatacctta acagttccaa
    10681 attttctctc agggataaat gagataaaaa ctcgactttt tcaattaaaa ttcctgcatc
    10741 ctgaatataa tgatttttta tcccgtaaac tttaccatct tgaagaactt ttcctttgtc
    10801 aagcttaata taaccagcaa gtacctttaa aagaaccgtc ttgccagatc cattatcacc
    10861 tttaagtcca taaatttttc ctgattgaaa caccaaattc aactgattta aaataggtct
    10921 tttcccataa attttctgtc catttataat ttcaagtttc atcgtttatc ctttcttaaa
    10981 tttctcttcc aagcgactaa caatcaacat aactaataag cttaagagta gtaaatacac
    11041 tgttacaata tgatccatca tccattcttg tcccacaaat gctaaaaaat agagaaaaaa
    11101 ggaaaaacca gcgcccgcac taatcagtgc tatcagataa gacagtagta agtacaacat
    11161 cattaactga gcaagtaaaa agaaaagtgc gactgttttg aaatgaattc ctagcggaag
    11221 taaaccaagg aaccagacaa gtaaatcttg agtaaaaaat ttagaaatga caaccaatcg
    11281 tttccttgta taatcgaaaa aggagcttga ttgatagcga atcaagtgat ggtaatggtc
    11341 tgccaaatca ctttcaagta aaatgacaga gagccatcct accatgaaaa gcgaaaggtt
    11401 taacaagagt ttggggattt ctaaattcgc ttcagaatag tcattatagg aaaagattga
    11461 aatcaattct ctcttgaaaa agataacagc atcctgcttt tgaaccgctg ttgacaatag
    11521 atagtttatc aaaatcatca tcagaactat acgaagtagt aaaacgatct ttctctttag
    11581 ccaaatattg ttaaaattct taaacattat cttcatattt ttcaagcacc atataaggga
    11641 caatataaag gatataagga gtaaagagtt tcatcaaact tacatcccca tagctagctt
    11701 gcatcaaact cgtcatagga accatatagt aaggcaaggc actatagagc agcatagaac
    11761 caagccaaag aaacatcaaa taggtgattg ccgaacgagt cacattcccc acataatcaa
    11821 ctatttgtaa aaaatagatt gcattgatga aaataccgat tagtaggaca caagtaaaga
    11881 acaaatagct ttttatctct ccatctagga gtctttgtaa accacttcca tcagaaaata
    11941 tagaattcca tccaagagga gaaaaagtcc caaagaaata ggttataatt gcaattatca
    12001 gcacagtcac taaatatatc aaacaaggga tacttgcaac ttgcaaagtc aactttcttt
    12061 ttaacccttg ataactcact tctcttccaa tactcaatcg taaaacttta tttttcagct
    12121 caatatattg aaaacctagc aaaacaatga tgattggaat aataaatgat tgataaaaac
    12181 ctagattgaa ctggagaata cgaaaatcta atgctgattt taataagtca tttttaattg
    12241 cttgtccatc gaatttagct agatcgggcg catgaatatc aaaaaagaaa taagtcatca
    12301 aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag taagacataa acaaatttat
    12361 gccttgccaa agttaagaga ggaatcttca taagccacct cctacaaata gaaagtaata
    12421 taatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaagttg ctcaaagcac
    12481 tgctttgagg ttgtagataa gactgacgaa gtcagttaca tatataatcc aaggcgacgt
    12541 tgacgtggtt tgaagagatt ttcgaagagt ataaatcaat gccttccgcc tttagatttc
    12601 cctagttccc gcctcaagcg aatcattttt ttgaaaaaga cataggctaa ccaatcacta
    12661 gcaaaagcga taagtagtaa taatagccaa ataccccata acttgatatc tgtcaaattt
    12721 ctcaagacga tattgaaaaa cagaactgaa aaaactgtcc aagcaaggct aaaaagagca
    12781 tagagggtga tgtaaatcca gtaaaaatag taaaaaattg ggaaaaattt actttctcta
    12841 ttatccttgt caatccagct gaaaaagtaa aaacagggta ataagattat cattttaaac
    12901 aagtgttcca tcacaaacct cctcttttaa attgttttct ttagtttcgt tctattaaat
    12961 gttattacca atataaacct tggaatagcg tgtaataaat gattttagag gtaccataag
    13021 gccacctcct acaaatagaa accgatataa atcaatgcct tccaccctta gacttcccta
    13081 gttcctgtct caagcgaaac atttctttga aacaggaata agttaaccaa ttcataccaa
    13141 tagctagcag aataaaaaga aaccaaatgc cccataactt gatatctgtc acatttctca
    13201 agacggtatt gaaaaacaga actgaaacaa ctgtccaagc aaggctaaaa agagaataga
    13261 aggggatgta aaaccagtaa aaataataaa aaattggaaa aaacttacta tttctgttgg
    13321 ccttctcaat ccagttatca aaataaaagt acggtgctaa aagtaagaat ttaaacaaat
    13381 gttccatcac cgacatcacc ctctttcttt tgatagcgtt ttctattatt ttattatatc
    13441 aaaaaaatcc ggaactgtca ttccagattc tactttttta tttgcgtttt cttgcgatga
    13501 gatgaatcgg tgttccctca aaaacaaagg ccttgcggat ttgattttcc aagaaacgca
    13561 ggtaagaaaa gtgcatgagt tcttcttcat tgacaaagat gacaaaggtt ggtggtttgg
    13621 ttgccacttg ggtcgcatag aaaatcttga gacgttttcc tttgtctgtc ggtgttgggt
    13681 tgatggcaat ggcatccatg atgacatcgt tcaagacagc tgatggaata cgtgtatttt
    13741 gactttcgct gatttgctta atcatctcag gaagtttgtg gagacgttgc ttggttaaag
    13801 ctgatacaaa gataatcggt gcgtaaggca ggtattggaa ctgctcacgg atatcttctt
    13861 cccagttttt catagtgtgg ttatcttttt caagcgtatc ccacttgttg accacgataa
    13921 tcatcccttt accagcttca tgggcaaatc ctgcgatacg cttgtcgtac tcacgaatgc
    13981 cttcttccgc attgatgacc atcaagacca catctgaacg gtcaatagca cgcatggcac
    14041 gcataacaga gtatttctca gtattttcat aaaccttacc agacttacgc ataccagccg
    14101 tatcaatcat ggtaaactct tgaccatctg tatctgtaaa gtgggtatca atggcatcac
    14161 gagttgttcc agcaacagga ctagcaataa cacggtcttc tcccaagata gcattgatca
    14221 agcttgattt tccaacgtta ggacgaccaa tcaagctaaa cttaatgaca tctggatttt
    14281 cttcctcata ttcatttgga agattttcta cgatcgcatc tagcacatcc cctgtaccga
    14341 ttccatggac agatgagata ggcaatggtt cacccaaacc gagagcatag aaatcatata
    14401 tatcatttct catctcaggg ttgtccacct tgttgactgc gaggataact ggtttgtggg
    14461 tcttataaag cttacgagct acgtattcgt ctgcatcagt aattccttcc ttaccagaca
    14521 cgacaaaaac gataacatct gcttcttcca tggcaatttc tgcctggtgc ttgatttgtt
    14581 ccatgaaagg agcatcgaca tcatcaattc ctcctgtatc aatcatgcta aaagaacgat
    14641 tgagccactc acccgttgca taaatacggt cacgtgtcac tccttcgaca tcttctacaa
    14701 tggagattcg ctcaccagcg atccgattaa atagggttga tttcccaaca ttgggacgtc
    14761 ctacaatggc aatagttggt agggccataa tttctcactt tctacaataa tttcttctgt
    14821 tcaagatttt ttctagttga gcttggttca gcttgaccaa actgttctgc taggcgctga
    14881 ctccagcttg tggtcgcacg cgccccagca tagtcagcct gaacacggtc ataagcttgg
    14941 attgcctcag ttgactgttc ttggtattct tcctcaaaga caacattctc tagtggcagt
    15001 ctcggtttca tatcatgatg ttgatttggc acacccagtg ccatcccaaa gacagaatag
    15061 gtgtagtcag gtaggttaaa gagctctgcc acttcttcag acttgtatcg aaccaaaccg
    15121 ataatcacac caccatagcc caagctttca gctgccaaca aggcgttttg tccagcaaga
    15181 gctgcatcga ccgaactaat caagagacct tccacacctt ggggttggaa ggtgtcggta
    15241 tgaagtctgg ctcccttttc tgctcggttc aaatctccga caaagagaag gaaaacagca
    15301 gactggcgaa tggcttcttg aggtaccaat tcatacaagg catctttctt ctcttgactt
    15361 cgtaccacaa tcacagagta ggattggaaa ttcttccaag atgatgccat ctgggctgct
    15421 gtcaaaatct catttaagtc tacttgggga atttcttgct ctttaaacct gcgcactgaa
    15481 gtatgagcct tcatcaattt aatggtttct gtcatcgacg gtttactcct tctaaacgag
    15541 tctcctcagc caaataacgg atgcgttcca tgacccgtct ggcttcccag gtttcgtcat
    15601 ttccatgttt cactttcgca aaatgcttct ccaaatcttc aaagttgaag ttggatgtga
    15661 aaaaggtcgg taaattttcc tgcatccgat attggagaat gacctgcagg atttcatcac
    15721 gcacccaagc ggtggattgc tcggcgccaa tatcatctaa aatcaggacc tcagacagct
    15781 taatctcatc caccaaggtc ttaacattgc catcactgat agcatttttg acatcaatga
    15841 caaagctagg atagtggagg agagttgatg aaacaccacg tttttctgat aaatcatgag
    15901 ctaaggccgc caccatgaaa cttttaccca caccaaagtc tccatataag taaagacctt
    15961 ttcgaatagc tggatattgc tccacgaagg ctagtagctt ttcaaaaact ggtaagcgcc
    16021 ccaaatcatc caagtcaact tgagccaaac tagctttctt gagactggct ggtagattga
    16081 ttaacttgag acggttctta atagccgctt ctttttcagc cgcgattagc tcaggagttt
    16141 cttcatatga aacatctgca tagccatgat tcttaaccaa aatcggcttg tagcctttgg
    16201 caatataatc cgtatcccca cggagaaact tgtcacgctc ggtgatgtac tgattaaact
    16261 tggagatact gcgatttaat tcctctggag tcaaggattc ttgctggata aaagccgcaa
    16321 catcagggtc cttcatgatt ttctggacca aatcttgata ataaaaacgg ctgggttgac
    16381 gtttgagtac gtctccgaca ctttccatct aatctcctcc tttttctaat cgagctaata
    16441 gttcttgctt cttacgttct agttccagac gagtttcctc gctggtttca ttcttatatt
    16501 caggattact ccatttagga atattggttt ttgctggggc agtctgattc tgtttttgtg
    16561 tttttgtttt ctgccctcgc tcacggatgc gcaagactgc cttttctgcc gaatgaatct
    16621 tttgataggc atagtcattg gctaccttca tggcatattt ctcattgata tttgccgaat
    16681 cgaccttatt aaaggtcaat aaaagaatga tattgatgac ttcgtccagc aagcccaagc
    16741 cagccatctg ttgcaagagt tctctttctg tttgggtaat ggttcccttg cgtgtttgct
    16801 tgatttctgc caagaactgc agggcagttt tacttttggc ttctttgata atggttgttt
    16861 ccttaagact aaagtcagag gaaactggtt tttgagcaat tttttcacgc atgcgtttgg
    16921 ttgaaataac ctgagaaaca gctgttgact tggccaattg ataggtttca aaccaagtcc
    16981 atttcttctc ctcggcaata gcaaagaggt ttaagacatc ggactgctca tccgcaaaac
    17041 gaagtccatc tcgagccatc agctggcgaa aatgttccaa gtcaaaatca ttggccactt
    17101 tcttcttgag accaaggtct tcttgactgc ctagttctgc caattctgga aagacttgat
    17161 tgagtgagac aggtatttct tcaccatcag cactttcaac tttcaaatcc tccacagcag
    17221 agtcgccaat ctttttctct aagagtctgc gataaacagg atgctccaag aagtcttgac
    17281 tagatagagg agcatggagg gctagctgat aaacatcccc cttttgatag agggtcaaga
    17341 gattaaaagc agataagatt ttcaatgatt ttatcagtct atccatccca aagttgagat
    17401 gattgaggat acttgaaaaa agatattcct ttctaccatt atcccaaaaa ctgattgtat
    17461 aaagataaag gctcagtgcc tcctgaccga taatcgggag gtagcactgt accagagatg
    17521 aggtatcttg cgacacccga ttattcttta gataagaaaa acggtcaatt ggcttcattt
    17581 atctttcctt tttcttttta gaggactggg tgatttgttg gagcaagctc tctaactcac
    17641 tgacatcctt aaaactacga tagacactag caaaacgtac ataggtaatc tcgtccaatt
    17701 cagccaactc ctccatgaca agtgaaccaa tgtcctcact ttgaatttca ttttcatttc
    17761 gaccacggag tttctgttcg atacgattga ctaccatgtt gatttcatca cttgacacag
    17821 gacgtttctg ggctgagcgg ataatcccat taaagatttt atctctggag aattgttccc
    17881 gtgtgccatc ttttttaaca accactaagg ttctttcttc tactcgttcg taggttgtaa
    17941 aacggtgttg gcactcgtcg cactctcgtc ttctacgaat ggtgttccct tcttctgctt
    18001 ggcgactatc gataacactt gacttggtag ccccacattt tggacaacgc atcctttccc
    18061 tccttatcgt tttcttttca ttataccatt ttttaagcga ttcccaaaac aattcttctt
    18121 tttgcttgac aagttttttg ttttgttgta ttatttaatt aagacaaaag gataagagaa
    18181 aggagactaa gatgtcctgg acatttgaca acaaaaaacc catctattta cagattatgg
    18241 agaaaatcaa gcttcagatt gtttcccata cactggaacc caatcaacaa cttccaaccg
    18301 tgagggagct agctagcgag gctggtgtca atcccaatac catccaaaga gccttatcag
    18361 accttgaacg agaaggattt gtctacagca agcgaacaac tggacgattt gtgactaagg
    18421 ataaggagct aatcgctcag tcacgcaaac aattatcaga agaagaattg gaacacttcg
    18481 tttcctccat gacccatttt ggctatgaaa aagaagaact accaggcgta gtcagtgatt
    18541 atattaaagg agtttaagcc tatgtcatta ctagcatttg aaaatgtatc caaatcatat
    18601 ggagcaacac cagcccttga aaatgtttct cttgacattc cagctggaaa aattgtcggc
    18661 cttcttgggc caaacggctc aggaaaaaca accctgatta aactaattaa tggcctctta
    18721 caaccagatc aaggacgtgt cctcatcaac gacatggacc caagcccagc aaccaaggcc
    18781 gttgtagctt atttgcctga tacgacctat ctcaatgagc aaatgaaggt caaagaagcc
    18841 ctaacctact tcaagacctt ctataaagat ttcaatcttg aacgcgctca tcatctactt
    18901 gcagacctgg gcattgatga aaatagtcgt ctcaagaaac tatcaaaagg aaacaaagaa
    18961 aaggttcaac tgattttggt tatgagccgt gatgctcgtc tctatgtttt ggatgaaccc
    19021 attggtgggg tggatccagc agcccgtgct tatatcctca ataccattat caacaactac
    19081 tcaccaactt ctaccgtttt gatttctacc cacttgattt ctgatatcga gccaatcttg
    19141 gatgaaattg tcttcctaaa agacggaaaa gtcgtccgtc aaggaaatgt agatgatatt
    19201 cgctacgagt caggtgaatc cattgaccaa ctcttccgtc aggaatttaa ggcctaagca
    19261 aaggagatta tttatgtttt ggaatttagt tcactacgaa tttaaaaatg ttaacaagtg
    19321 gtatttagcc ctctacgcag ccgtgctagt cctttctgcc ctcatcggaa tacagacaca
    19381 aggctttaaa aatctacctt accaagaaag tcaggctact atgctacttt ttctagctac
    19441 agtctttggt ggcttgatgc ttacacttgc gatttcaacc attttcttga ttattaaacg
    19501 cttcaaaggt agtgtctacg accgacaagg ctatctgact ttgaccttgc cagtttctga
    19561 acaccatatc atcacagcca aactaatcgg tgcctttatc tggtcattga ttagcaccgc
    19621 tgtattggct ctaagtgctg ttattattct ggctttaaca gctccagaat ggattcctct
    19681 ttcttatgtg attacatttg tagaaacaca tctccctcag atctttctta caggtatatc
    19741 cttcctacta aataccattt caggaatcct ctgcatctac ctggctattt ccattggaca
    19801 gcttttcaat gaataccgta cagcactcgc tgttgcagcc tacattggta tccaaatcgt
    19861 cattggattt attgaacttt tcttcaatct tagttctaat ttctatgtca attcactggt
    19921 aggactcaat gaccatttct atatgggagc aggtatagcc attgttaaag aactcatatt
    19981 catagctatc ttttatctcg gaacctacta catcttgaga aataaggtta atttgcttta
    20041 aataattttt acctagatat gtaacatact catagaacaa aagagaccag gcaaaaagtc
    20101 tttaaaatta gaaaacgcat agtatcaagt gttaaaaatc cttgatatta tgcgtttttt
    20161 gtgagctgac ttatttcctt tcgctatatc gcaaaatgaa ataagaacgg aacgatggga
    20221 ttttggaatt caaatcaatt tataagaatg ttttagaagt aatattatcc tattccagat
    20281 tcagttcact atacaattga gttttcaagc aacctgttta cataatgtgt acataattag
    20341 gttcgtgatt ccaccctttt cacctttaaa aacctcgctt tcgcaaggct cttctattta
    20401 taagataagg cacgtttaaa ggttttccaa atccctaaat catccgtttg aagaacgaga
    20461 ctagcataca tgcgtccgat aaatcctgtt gctaccaccg caaaaatcac tgtaatagca
    20521 agtgaaatcc atgcttccgc tccctccgca tagccattaa tcgttcgaaa cggcataaag
    20581 aaggtcgaaa taaagggaat ataagaacca atcttcaaga ggagattgtc accagctgca
    20641 cctagagctg tcactccaaa aaaaccaccc ataatcaaaa tcatcaaagg cgacaaggct
    20701 ttccctgagt cctcaggacg agaaaccata gatcctagga aggctgccaa gactacgtac
    20761 atgaaaagac tgatcaaaat aaagagcagg gtattcagtg agatagcatc tcccaagtga
    20821 tccaaaatac cagactgagc caagaatggc aaatctttaa agagcaaaac ggcagccaga
    20881 ccacctacaa catagatccc aatatgcgtt aaaatcacta gaaacagagc catcatccgc
    20941 gcatagaaat agtgacttgc ccttatgcta gaaaagacga cttccataat tttggtgcct
    21001 ttttcactgg caacttcctg agctgttaca cccgcatagg taatcagaat catataaaga
    21061 aagaatccta aggcacctgc tgcaattgtt tgaataaact ttttattttc cttggcttca
    21121 tcaatctttt ctgtgaattg aattgtctgc gctaagcgtt tttcctgctc ttgagacaag
    21181 gaagcagttg aacgattaag ctgattttgc agttcattga gtgtacctgt aacctcaaat
    21241 ttaattccat tttcaagcga tgtttcgcca tgataaactg cctttagaac actatcttct
    21301 tgatcaatgg tcaaataacc ttttaatttt tcttctttaa ttgcttcttt ggcacttgct
    21361 tcatctttat agtcgaagtt aacaccattt acattcttca gtccttctgc tacagatggc
    21421 actgttgtca ctactgccac tttattattt ttagacatag aagaaccttg gagatgccca
    21481 attcctacag agattcctaa aaagaggaac ggcgaaatca ccataaagaa gaaactccat
    21541 gactcgacat gtcgaagata ggtttccttg attacaaccc acatatttct catacttcca
    21601 ctcctgattc tagtttaaag atttcatcga tagttggcgc ttgttggtca aatgttgcga
    21661 tatattgacc ttgagtcaag attgggaaga gttcccttcc agcgctctca tcctccaaaa
    21721 tcaatttcca actgccttgt ttggtcaagc tcacctgttt gacatgagga agattttcca
    21781 attcttcctt gcttcgttca cttgaaacaa agagacgcgt tttcccgtat tgattgcgga
    21841 catcctgaac tggtccgtgc aagaccacac ggccatctcg gatcatcaga atatcgtcac
    21901 aaagttcctc aacattggtc atgacatggt cagaaaagat aatggttgct ccgcgctctt
    21961 tttcctgaaa aatgacttgt ttgagcaatt ctgtattaac tgggtccaat ccactaaaag
    22021 gctcatccaa gataatcagg tctggttcat gaatcagagt aataatgagc tgaatcttct
    22081 gctgatttcc ttttgacaga ctcttgattt tatctgtcag ctttcctttc acttccaacc
    22141 tcttcatcca ttgagggagt ttttctttga cttctttggc atccatgcct tttagagtcg
    22201 ccaagtagcg aacttgttca agaactgtca atttaggcat gagactgcgt tcttcaggca
    22261 gataaccaat ccgagcatag gtctcctgac gaatatcctg accatccaga ccgatttctc
    22321 cctgatattc taggaatttc aaaatactat ggaaaatcgt tgtttttcca gcaccatttt
    22381 ttccgactag tcccaaaata cgacctggtc gcgcttgaaa gtcaatacca aacaaaactt
    22441 gcttggagcc aaaacttttc tctagacttc ttacttctag catctttcac ctccgaaatt
    22501 tcttgcactc attatactcc tttttgatag cctttacaat gtttttgtcc atttttagaa
    22561 gactattgct gtgtaaaata tggcctggag cacttttata ctcaatgaaa agcaaagagc
    22621 aaactaggaa gctagccgta ggctgctcaa agtacagctt tgaggttgca gataaaactg
    22681 acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagtaact
    22741 atatctacgg caaggcgaag ctgacgtggt ttgaagagat tttcgaagag tattagtgat
    22801 aaatccatta tacagtagca aacttaattt ataccttccg ctcctcaact gtctattttt
    22861 aatcctgaat tgttatttga gtaactcctt tttcctcata aagttttctt cctctaaaac
    22921 ttctggaaaa aggctaatag tttcagacaa catttttata agaaacaagt tcatctgtca
    22981 tttcaagaag gagtaatcct ttatctacta atggacggaa cagaattcaa ccgcttgtcc
    23041 gatatgtttt ctaaggatta tatagtaaaa tgaaataaga acaggacaaa ttgatcagga
    23101 cagtcaaatt gatttctaac aatgttttag aagtagatgt atactattct agtttcaatc
    23161 tgctatatct attatgcaca cccctatagg atctaatgaa aatcacaaca ggctcattca
    23221 tagatagtta cctcaggaaa ctaagaaaac gactacaaag gaagtcgcat tcatcgaaaa
    23281 gtggattaac aactatccta aaaaatgctt gaactacaag tcccccagag aagacttctg
    23341 gatgactaac ttgaacttga aatttagcaa taattaattc accatctaac tatatttagt
    23401 aattatttca gaactgatta atattaaaat taactaacaa ttcaaaggat tcatactagc
    23461 cataaattac gtccatcaga gagagactct tactactttt agattttagt ctttctagct
    23521 tcagaataca tctaaacttt agggaaaatg actattcgaa agcgcgaatg cctcaaaatt
    23581 atctcagata agctattcga aacttagaat gcttttaaat ttatggaatt gcgattattc
    23641 gaaacctaga atgcatataa cctttagttg acagacctat tctaagtctc gaagggctat
    23701 ttactttcta ttccttatca aaaaagactc attccccctt tctcctccaa aatatggtat
    23761 agtagaaata tactatctat gaggagttta catgtcacag gataaacaaa tgaaagctgt
    23821 ttctcccctt ttgcagcgag ttatcaatat ctcatcgatt gtcggtgggg ttgggagttt
    23881 gattttctgt atttgggctt atcaggctgg gattttacaa tccaaggaaa ccctctctgc
    23941 ctttatccag caggcaggca tctggggtcc acctctcttt atctttttac agattttaca
    24001 gactgtcgtc cctatcattc caggggcctt gacctcggtg gctggggtct ttatctacgg
    24061 gcacatcatc gggactatct acaactatat cggcatcgtg attggctgtg ccattatctt
    24121 ttatctagtg cgcctatacg gagctgcctt tgtccagtct gtcgtcagca agcgcaccta
    24181 cgacaagtac atcggctggc tagataaggg caatcgtttt gaccgcttct ttatttttat
    24241 gatgatttgg cccattagcc cagctgactt tctctgtatg ctggctgccc tgaccaagat
    24301 gagtttcaag cgctacatga ccatcatcat tctgaccaaa ccctttaccc tcgtggttta
    24361 tacctacggt ctgacctata ttattgactt tttctggcaa atgctttgac acgtaaaaaa
    24421 tccgtttggt ttcccaagtg gatttttaaa gcgtagatta actatagctt gatactaaat
    24481 atactttggt atggaaatca tgcatatttt tcgatagtga agcgaggact tacctagcct
    24541 ttccaccgtg atagaaacac ctgaaatcta atggtttcag gtgttcggaa actttgagcc
    24601 tagtgtctca aagtttatgt atggaatttc gaagaaagtc gctaccgtcc gtaatcactt
    24661 aaggaaaggc tcaaaaatat tgttttcaac cacaaaatcc gtttggtttc ccaagcggat
    24721 tttgtgcttt attttgaaac ttcttttgca agaacaaagt tcccaagtgt ggcagaacca
    24781 tttcctgcga ctgctggcgt cacgatatag tcacgcacat ctggtactgg taggtaacca
    24841 ttaagaagag atgtaaattt ctcacggaca cggtccagca tatgttgttg agccatgacc
    24901 cctccaccaa agacaatcac gtctgggcgg aaagtcactg tcgcattaac cgcagcttga
    24961 gcgatatagt aggcttgaac atcccaaaca gggttgttga gttcaatagt ttccccacgt
    25021 acacctgtac gagcttccaa acttggacca gctgcatagc cttccagaca tcccttatgg
    25081 aaaggacaaa cacccttaaa ctctttttca atatccattg ggtgtctagc aacataataa
    25141 tgacccattt cagggtgacc cacaccaccg ataaactcac cacgttggat gacgcctgca
    25201 ccgatacctg taccgattgt gtagtaaacc aagttttcga tacgaccacc agcattgtta
    25261 cgggcaacca cttcaccgta agcagagctg tttacgtctg ttgtgaagta cattggcacg
    25321 tttagggcgc gacgaagggc accaagcaag tccacatttg cccagtttgg ttttggagtc
    25381 gtcgtgataa agccataagt ttttgagttt ttgtcaatat caatcggccc aaatgaacca
    25441 actgcaagac cagcaaggtt atcgaatttt gagaagaact caatggtttt atcgattgtt
    25501 tcgattggag ttgttgttgg aaattgtgtt ttttctacaa cgttaaagtt ttcatcaccg
    25561 acagcacaga caaactttgt accgccagct tccaagcttc catataattt tgtcatgata
    25621 aacctcttgt ttttattttc tttattatag catacttcga aagtctaaat gtctctattt
    25681 tttagatttt cctctgtaaa tcttactatc taataaaaac gaacaaatat gtcatttgtt
    25741 cgttttcaca ttagagagga ttgattagat tttcacttcg atcacagcat cccccttagc
    25801 aactgaacct gttgcgactg gagctactga agcgtagtca cctgtatttg taacgataac
    25861 cattgttgta tcatcaagtc cagctgcagc gattttgttt gagtcaaatg ttccaagaac
    25921 atcgccagct ttcaccttat taccttgagc aacttttgtt tcaaaaccgt caccgttcat
    25981 agatacagta tcaataccaa catgaatcaa aacttcagca ccatttcttg ttttcaaacc
    26041 aaaagcgtgc cctgttggaa aggcaattga aacttcagca tcagctggtg catagaccac
    26101 gccttggctt ggtttcacag cgataccttg tcccatagct ccacttgaga agactgggtc
    26161 attgacatca gcaagagcga caacatcacc gacgatagga gttacaagtg tttcattttg
    26221 aagagctgct ggcgcaactt cttctttttc ttcagccact tcagcttgtt ttgcagctgc
    26281 agttgcgtct acttcatctt cgtaaccaaa catgtaagta aaagcaaaac caagggcaaa
    26341 tgatacagct accataagaa ggtattgtgg aagttgtccg ttaccaacat aaagcattgt
    26401 accagggatg atggtgatac cattaccagt accagcaagt ccaaggatag aagccaatcc
    26461 accaccgatt gcaccagcaa tcaatgaaag gaagaatggt ttacggaagc gcaagttcac
    26521 cccgaagata gcaggctctg taatacctag gaaggcagaa agagcagccg ggaaagcaag
    26581 tgttttcagt tttggatttt ttgttttaac accaaccgca acagtagcag caccttgagc
    26641 tgtcatagca gctgtgatga tagcgttgaa tgggttagca tggtcagcag caagtaattg
    26701 cacttcaagc aagttgaaga tgtggtgcac acctgacacg acgatcaatt ggtgaacccc
    26761 accaatcaag aaaccaccaa gaccaaatgg catgctaaga atcgcttttg tagcaataag
    26821 gatgtagttt tcaacaacgt ggaaaactgg tccaatgaca aagagtccaa ggatagacat
    26881 gaccaaaagt gtcacgaatg gtgttaccaa gaggtcaatg acatctggaa caacctcgcg
    26941 gacagctttt tcaaatttag ctccgacaac cccgatgatg aaggctggaa gaacggaacc
    27001 ttgcaaacca acaacaggga tgaaaccaaa gaagttcatc gctgttactt caccaccttg
    27061 agcaactgcc caagcgtttg gaagtgagcc agagacaagc atcataccaa gaacgatacc
    27121 aacggcagga tttccaccaa atacacggaa ggttgaccac acaaccaaac ctggcaagat
    27181 gatgaaggct gtatctgtca agatttgtgt gtaagttgca aagtcacctg gaagtggcat
    27241 ttcaagagcg ttgaaaagac cacgcacacc catgaagaga cctgtcgcta cgataactgg
    27301 gatgattgga acgaaaacat caccaaaagt acggatagca cgttggaacc agttcccttg
    27361 tttagcaact tctgctttca tgtcatcctt agatgatgtt ggtaatccaa gtacaacaac
    27421 ttcatcgtac attttgttaa ctgtacctgt accaaagata atttggtatt gccctgagtt
    27481 aaagaaagca ccttgaactt tttccaagtt ctcaatcact tctttattga ttttctcttc
    27541 atctttgacc atgacacgta gacgtgtcgc acagtgggca acactattga cattttcacg
    27601 tccgcccaag gcatcgatga ctttttttgc aatttcctga ttgttcattt gcaaaaatct
    27661 ccttatataa cattttgttc ttgtttgaaa gcgattttat tcgcccttac gactattatt
    27721 ttatcatgtt ttaaaaatat gtcaagcgtt ttgcagaaaa atattctatc cacttagtgg
    27781 gcaagcttta gattgattgt ttttgactgt ttcatcagga attccttgaa aaataagttt
    27841 gaaaccttgg ttaaaaagtc ttttatttca ttatctttca cattttcgta aaaatttgat
    27901 tgatttctgt atttatttta tgataatcgt ttgatagttt ttcctctttt ttaacataaa
    27961 gggcttgcat tttttatcga aaacagttac tattaaaagt gataagattt ttggaggaat
    28021 gaatggaatg gacaactgag cgtcgttaca gactttatca agattggacg caagaagaaa
    28081 ttcaacatat aaaggaaaat atggcacaat ctccatggca tactcattac catgttgagc
    28141 caaaaacagg acttctcaac gacccaaatg gcttttctta ctttgatggc aagtggatcc
    28201 tcttttacca gaattttcct tttggtgcag cccacggttt aaaatcttgg gcacagctag
    28261 aaagtgatga tttgattcac tttaaagaaa ctggaatcaa agttttacca gatactccat
    28321 tagatagtca cggtgcctac tctggttctg ccatgcaatt tggcgataac ttattcctat
    28381 tttatacagg aaatgttcgc gatgaaaact ggatccgtca cccataccag atcggtgctt
    28441 tgatggacaa ggagggtaag attacaaaga ttgacaagat cttgattgac cagccagcag
    28501 actctactga ccacttccgc gatccacaaa tttttaactt taaaggtcaa tactatgctg
    28561 tcgtcggtgg acaggacttg gagaaaaaag gcttcgtccg tctctacaag gctgtcaata
    28621 acgactacac aaactggcaa gcagttggcg accttgactt tgctaacgac cgtactgcct
    28681 acatgatgga atgtcctaat ctggtctttg tagaggaaca gcctgtcctt ctctactgtc
    28741 cacaaggatt ggataagaaa gttctagact acgataatat ctttccaaat atgtataaga
    28801 ttggggcttc ctttgaccct aaaaatgcca aaatggtaga tgtgtctcaa cttcaaaaca
    28861 tggattacgg tttcgaagcc tatgcaactc aagccttcaa cgctcctgat gggcgtgctc
    28921 tagcagttag ctggcttggt ttgccagatg tttcttaccc atctgaccgt tttgaccacc
    28981 aaggaacctt ctctttggtc aaggaactca ctatcaaaga cgacaagctc taccagtatc
    29041 cagtcgctgc tattaaggac cttcgtactt ctgaagaagc cttctcaaac cgttcccaaa
    29101 ccaagaacac ttacgaactt gaactcaact tggaagctaa tagccagagc gagattgtct
    29161 tacttgctga taaagaaggt aagggacttt caatcaactt tgaccttgta aacggtcaag
    29221 tgacagtgga tcgtagccag gctggagagc agtatgccca agaatttggg ataactcgtt
    29281 cttgccctat cgagaatcag gctactactg ctacaatctt catcgataac tctgtctttg
    29341 aaattttcat caataaagga gaaaaagtat tttctggtcg tgtcttccca catgcggacc
    29401 aaaatggtat cctgatcaaa tctggaaacc caactggaac ttactatgaa ttagattatg
    29461 gtcgcaaaac taactgatgt cgccaaactt gcaggcgtca gtcctactac cgtttctcgg
    29521 gttatcaata aaaaaggata tctatctgag aaaaccatcc aaaaagtcaa tgaagccatg
    29581 agagaattag gctataaacc caacaaccta gctcgtagtc tgcaaggaaa atcagctaag
    29641 ttaatcggct tgattttccc caatatttcc aatgttttct atgcagaatt gattgataaa
    29701 ttggaacacc aactcttcaa aaatggttac aagaccatca tctgcaacag tgaacatgat
    29761 tctgagaagg aacgcgaata catcgaaatg ttggaagcca atcaggtgga cggcatcatt
    29821 tctggtagtc acaacctagg aatcgaagac tacaatcgtg tgacagcgcc gattatttcc
    29881 tttgaccgaa acctatcgcc agacatccct gtcgtctcct ctgacaacta tgctggtggg
    29941 gttcttgctg cccaaacctt ggtcaagaca ggtgcccagt ctatcatcat gattacaggg
    30001 aatgacaatt ctaattcgcc aaccggactg cgccacgctg gttttgcatc cgtactccca
    30061 aaagctccta ttatcaatgt ttccagtgac ttttctcccg tcagaaaaga aatggaaatc
    30121 aagaatatct tgacccggga aaaaccagat gccatttttg cttcggatga tttgacagct
    30181 attctggtca ttaaaatcgc tcaagaattg ggcatttctg tcccaaaaga gctcaaggtc
    30241 atcggctatg atgggaccta ctttatcgaa aattactacc ctcaattggc tactatcaag
    30301 caacctttgg aagagattgc ttgtctcact attgatcttc tcttgcaaaa gattgaaggc
    30361 aaggaagtcg ccacaactgg ttacttctta ccagttacac tattaccagg aaaaagtatt
    30421 taaacacaag aaaactcaga ccgattcgtc tgagtttttt atgatcttaa attttcgaga
    30481 tagcgctggg ctgtctctag gttaaaggtt ttatctgcga taagctgctc gactagggga
    30541 gcaacttcag attcactagc cccagctagg agagctaggg atttggcctg tagtttcatg
    30601 tggccttgct ggatgcccgt acttaccaag gctttgaggg ctgcaaaatt ttgagcaaga
    30661 ccgatggaca cgataatctg tgctaattct ctggcagaag gatttcctag tagatcatga
    30721 ctgagagcta cacgtgggtt gaggccgata gagccaccct tagtcgctac aggcatgggc
    30781 agggtcatct caccgaccaa ttcttctctt tcaaggtcca gcgtccagca actaagacct
    30841 tgataacgtc catctcgact ggcaaaggca tgggccccag cttcgatggc acgccagtca
    30901 ttaccagtgg caatcaaaat cgcatcaata ccattaaaaa ttcctttatt atgagtagca
    30961 gctcggtaag gatcagcctg cgcaaactga ctagccaacg caattttctc cgcaatctct
    31021 cgtccttgat ccttttggcg gctcaagtag cgaaaggcga tgcgacagct tgcagtcacc
    31081 agagaatcag tcgcgtagtt ggacaggatt cccatgagac tctgtccctg actgagttct
    31141 tctaagactg gtttcaaggc ttccagcatg gtgttgagca tattggcacc catggcttcc
    31201 tgggtatcaa catgaatata aacaacgaga aagtctggtt caccttttat ctgctcgaca
    31261 tgcaggtcac tcgccccacc cccacgttta acgatagaag gataggcttg attggcaagc
    31321 tccaagagct ccgctttctt gctggcaatc ttctcttgcg ctagtttagg attagcaatt
    31381 tgataaaggg ctacctgccc aatcatctgg cgctgatgga cttgtgcagt aaaaccacct
    31441 gcacgcttga tgattttgct ggcatagctg gccgccgcaa ccacagaggg ttcttctgtc
    31501 acatagggaa cggtgtattc ctgaccgttg acaagtacct ccggaaccag cgaataaggc
    31561 agagaaaaag ttcccaccac attctcactc agctggtctg ccacagtcac actcatctgt
    31621 tcatccttct ccagactagc ttgtctctca ggactaagga gcgcctgagc ttttagcagc
    31681 tcgaggcgct cttggtatga ttttttagaa aatccattcc aacttatctt cattattttt
    31741 caaccttgct ataacggcgt tggtggtcaa gaatttcaac caaggcaaaa tcttgatttt
    31801 catagccagc aaactgggca gagtttgttt catccaagtt tacttcctca aaaaagacct
    31861 tttcatagtc tgcaacggat agggcagttc gttggttgag cttgttcaag cggtctttat
    31921 ccaaataagc ttcatatcct tcaaccaatt caccactgaa gaactcagcc acagctccac
    31981 ttccgtaact ataaagggcg attttatccc cagctttcaa gctatctgta ttttccaaga
    32041 gagacaaaag tccaaggaaa agtgaacctg tgtagatatt ccccaccttt tgactgtaga
    32101 gaatagactg gtcaaaatgc ttttgtaaga ggtctttttt ctcttgaggc aggctcttat
    32161 ccatgatttt tttcaagcct tttagcgcta atttaggata aggcaagtgg aaacaaacag
    32221 ccgcaaaatc atccagagta agctggtagc gtttttgata ttcaagccaa gtcgttttca
    32281 aactatccaa gtattgttgg gtagaataaa caccatttac ataaggagtt gtcgagtaat
    32341 ttggtcgcca gaaatccatg atgtcacggg tctgagctac attgtcatta ttaaaggcca
    32401 tcatgcgtgg attttgtgta atcaacatag ctacacttcc agcaccttga gttggttctc
    32461 ctggagtttc aataccgtat ttggcaatat cactggcaat gaccaagacc ttggactccg
    32521 gagaattttc cacatgcaat ttggcataat gaagggcagc agtcgctcca taacaggctt
    32581 ctttaatctc gaaactacga gcaaagggct ggatgcccag caagccatgc acaaagacgg
    32641 ccgcagcctt actctggtca attcctgact cggtagccac aatgaccatg tcaacttctt
    32701 gtctttcttg ctcagttaaa atagagtcac tagcactggc cgccaaggtc acaatgtcct
    32761 cagttaggga cgcaatactc aattccttga gtaagagtcc tttacttaat ttttcagggt
    32821 caattcccct cgcttctgct aagtcttgta atttcaagac atattgactg gtcgcaaaac
    32881 caatcttatc aataccgatt gtcatattta cctctgtttt atcattcatg taaaaaatcg
    32941 ttctatacta ttttatcaca aatggcagta aaagagagaa aaaagacttg attcaccaaa
    33001 tcaagcctct tattggtcat cattttaaag aatgattagt tgctagagag ttcaccgata
    33061 taagtagctt tataagctcc attcacagtt atcagctcct ggaggatcaa atttcctgag
    33121 taagtccttc ccatctcatc tacaaatttt tgataaaact gactggtcgg aatttctctg
    33181 acatccttat caaatgtctt atcaagtgtt ttactaacct tctcagcaat caattgatgc
    33241 tcttgccatc cactttgaaa ctctgagccc gaactagaaa ccatgactgg gataaacaac
    33301 aaggtcagta gacttacaga caataaggaa aatagtagac ttcctgcaaa actagaatcc
    33361 tagttcatga ttgataatac cagcaatcaa attcattcgt aatccgaagc gtttacgatg
    33421 atttcgatag gttgttgaaa atattttaaa cgtttttact ttggcaaaga tgttctcaac
    33481 cttgcttctc tccttagata gcgcatggtt ataggcttta tcttcagcta ttagcggctt
    33541 gagtttgctg gatttacgtg gagtttgtgc ttgaggatat atcttcatgg gcccttgata
    33601 accactgtca gccaagattt taccagcttg tccgatattt ctgcgactca ttttgaacaa
    33661 cttcatatca tgacaatagt tcacagtgat atccaaagaa acaattctcc cttgacttgt
    33721 gacaaccgct tgagccttca tagcgtggca tttcttttta ccagaatcat tcgctaattc
    33781 tttttttagg gcgattgatt tgtacttccg tcgcatcaat cattaccgtg tcctcagaac
    33841 tgagaggagt tcttgaaatc gtaacaccac tttgaacaag agttacttca acccattggc
    33901 tccgacggag taagttgctt tcgtgaatac caagatcagc cgcaatttct tcataagtgc
    33961 ggtattctcg cacatataga aagcgttgtt aatttattta tctcattttt cagaaaattc
    34021 ttttatttct gtaaagtcta cgatactcga tgtgtcttta tataatgata cagtctgaga
    34081 atcactgttc cgctagccat tccaatagag attaccagag ccaacatgac aaccaaggtc
    34141 gcacttgcca gtgctttatt atagtcccct gtcacaaaaa aggcagttgt tcggtaggag
    34201 agataacctg gaaccagcgg tgccaaaatg gccaagataa agaccacagc aggtgtctta
    34261 taaagaatac ttaaaatctg gctgacacaa gaaccaataa tggctgcaat gaaggtagct
    34321 acaatgacat tggtcggttc cttgagcaag agatagatta gccagacagt catgcccaaa
    34381 atccctccag gtaagagcat agaccgttgc acattgagta cgattaaaaa agtgataatg
    34441 gcaagaaaac ttgctactgc ttgtaataaa aaggttgtta gtgtcatatt agttcatcaa
    34501 taccaaggcg acagaagttc ctgcccctaa agcgagggta atgagcaggg attcaaacat
    34561 cttactcata ccagagttta tgtggttggt cataatatca cggaccgcat tggtcaaggc
    34621 aatacctggt acaaacggca tgaccgcacc agctataatc aaatctgccg ttgaaggaaa
    34681 acctgtgtag cgagcccaaa actgggcaat tatcccaaag acaaaggctc cagcaaaggc
    34741 tgtcacaaag ggaattcgga taaatttttc cacatagagg gaaaaggcaa aaccaaataa
    34801 ggtcgccact cctgccccaa gtgcgtcgta gatatttccg ctaaacataa ctgaaaagaa
    34861 aggagcacta aaggtcgcag ccagagttac ctgcaactta gtatagggaa ggggttgagc
    34921 ttgcaaggcc gtcaattgct taaaggctgt ttctaagtca atctgccccc caactagctg
    34981 acgagaaatc tggttcacat cgcagacttt ttcgatgtta taagaagagg aggtcacgcg
    35041 cttcatgcgc gaaatattgg tattttcaat agagaaaaag atagcggcag gcatggcaag
    35101 gacattgcaa tccacaatcc cctgcgaatg cgcgattcga atcatggtat cttctacacg
    35161 atggatttct gagccacttt taaggagaat agtccccgct agcataatca catcaatgac
    35221 ggcatttaat tcttttgatt cttccatgct ttcctccttt tatcaactcc ctctattcta
    35281 tcacaaatct ggactcaaaa aaaatctttg ccatgaaatc atgacaaaga ttgattactc
    35341 attttgatta tccatctact tttaaggagt agctgaagtt gttttaggtt tgtagattga
    35401 aatcttgact ctagtcttat tgaggtctac cttttcacct gctctaggac tttgttcaac
    35461 aaccatgcct tctgcactac ctgcaggcgc tgtcgtcact tctacaactt ctatattagc
    35521 ttccttaatc ccaacaattt gaatcaaatt gttcttagta aactccaagc tggaaccaat
    35581 gtaactcggc atggcaacac ttgtaacttt tttagctact gtcaagacaa tttgagtagg
    35641 tttactcaca tcataagtcg ttccggcacc tggactttgt ttcataatcg ttcctggttc
    35701 gctttcgctg gactcttctt cctctatctt aatcaaattc tcaggaacct tcttctgctt
    35761 gagttctgag attacttctg tagagttccg tccaatatag ttccctaatt gaatcgtcgt
    35821 agctttttta gctactgtca aaataatttg agttgccttg ctcaagtcat aggtcgtacc
    35881 ttctggtaga ctttgcttca ggaccgttcc agcctcactc tcattcgact cttcttcctc
    35941 aattttaatc aaattatctg gaactttttt ctcttttaat tccgcgataa catcagaaga
    36001 tttccggccg acataattac taatttggaa ggattgtttg cctgatgaga caaccagatt
    36061 gattttcgtt ccttcttttc gaccagttcc agcgccagga tctgtacgga taatccgccc
    36121 ttcttccacc ttttcactag cctctgtctt ctcctcacca atctcaaaat tggctttttt
    36181 gagcgttgcc ttggcctctg caactgtctg acctgccaca tctggaatgg caatggttgc
    36241 aggagttctg gatagtatcc aaataagaga agctgccacc aatacaaggc tggccaacaa
    36301 aatcaggtaa cgcatcttaa atctatgttt tttcggtgct tgtggttggt aagtttcctc
    36361 tgtcacagcc tggcttgggt ttttgattga tttgtgttct gtctgcgctt gaaccttagg
    36421 aatagatgtc aaggtactct gagaaacctt cggcaaggtc ttggtatctg ccttgctcgt
    36481 ttcatcaaag attaacttac tttcatttct acgattgtag gacaagctac tagacaagtc
    36541 cacatacatc tctgaaaccg agcggtagcg attggtcaac tttttagcag ttgccttgat
    36601 aataacattt tctaaagcct gaggtacaga tggattttct gcaataacgg acggcagggg
    36661 tttctggaaa tgctggaggg caatggtcac cgcgctatcc ccgtcataag ggatatggcc
    36721 tgtcaacatc tcatagaaaa taatccccat ggcatagata tcactctgca cagtcgcctt
    36781 agaaccacgc gcctgctctg gtgacaagta atgaactgag cccaacatcg agttagtctg
    36841 ggtcagactt gtctctgcaa aggctacagc aatcccaaag tctgtgacct tggccgtccc
    36901 atctggtgtc aaaaggatat tttgaggttt caagtccctg tgaacaattc ctcgagtatg
    36961 ggccaagcgc atagccaaga gaatttgtcc catgatacgg actgcttctt cattagaaag
    37021 aggataatgt tccttgatat agcgtttgag gtctagtcca gcaacatact ccattgcaag
    37081 atactgttga ccgtcttcct caccaatatc tgttatccga acgatatgag gatggtctag
    37141 atctgccata gctctcgctt cacgctgaaa acgagctaca gctatcgggt ccgtctggta
    37201 gttggtcctc agaaccttca ctgccacttc ttccccatct aagattaagt ctttggctag
    37261 gtagacatcc gccatacctc ctcgaccaat ctgtttgaca atccgatagc gtccggcaaa
    37321 aatcttgccg atttggatca ttctgcatcc tcctcgttca tagaaacaag ggcaaccgta
    37381 atgttgtcta aacctcctgc attgttagca aaacgaacaa gtgtctccgt tttatctgct
    37441 aaaggaatat cactggttac aatatcacga atctcactgc ctgaaatcat gttggtcaag
    37501 ccgtcactat tgagcaagag atagtcacct gactcaagga taactgtccc aaaatcaggc
    37561 tgaatttcat ctttttgccc aatagactgg gtgataatat ttttttgcgg atgagcttct
    37621 gcctcttctg gtgtcaattg accagccttg agcaattcat taaccaaaga atgatcactc
    37681 gtcaactgat ggtattcttc tccacgaatc aagccgatac gcgaatcacc aatatgagca
    37741 tagatagcct gattatcaat aatagcaagg acttccaaag tagttcccat gcctctgtaa
    37801 gcttcatcct gaccaagctg gtgaatcttt tgattttcaa tttctaggta atgggcgaac
    37861 cattcacgca cttcattgac tgtatcgatc tgggtatcaa cccaagctac acccaggtct
    37921 gtgaccgcca tttcactagc gatattccct gcgcgatgac ctcccatccc atcagctaaa
    37981 ataatcatgg tacgtccagc tctattgaca tagtggttga catagtcttg gttatttgtt
    38041 cgtttctgac caacatctgt taataatgaa atttccatgt gtcagttcct tcctaatccg
    38101 atatcttgcg aaattgactg atgaagaatc catcacttcc atacaattca ggtgtaatga
    38161 ggatacagcc gtctttcatg atatccttac attcatgttc tagttttacc tgctcgaact
    38221 cgggatgact ctctaaaaag gccttaacga cttgaaaatt ctcctctgag acgatagtgc
    38281 aggtgctata agttattata ccacctttgc ctagtatttg acaaacacta cctaatattt
    38341 ctaactgaat ttcctgcaag gacgcgaaat ctgccgtttc tttattgtat ttgatatctg
    38401 gttttcggcg caaaagaccg attcctgaac aaggagcatc caccaaaatc ttatcaaagg
    38461 aatcctggtc aaaaaactca tgcacctttc tggcatccaa tttttgagtt tgaacccgat
    38521 ctgcaactcc cagacgttgg gcattttctt gaattaaatc caacttgtgg tcgtacaagt
    38581 ccagagcagt aacctgacct gtcgtaagat aagaggctat atgggctgtt ttcccacctg
    38641 gagccgcaca ggcatcaagc actcgctcat caccttgtaa atcaagcgtc ggagcaacca
    38701 gctgactgga ctcatcttgg atggtaatgg ctccattcgc aaacaaatta tgccctgcaa
    38761 aatgcccctg ctccttaacc agaccagtgg ttgctaaaag ggaattattc gcctccaaca
    38821 aggcttggat ttcctctttt cgacttaggt ctgttacacg aatactggct ttgtttcgca
    38881 ctaacaggct ttcaaagatg gcttttgctc tctcctctcc gtattcttcc ttgagtttgg
    38941 caactagcca aactgggaga gaataggcaa tggagtcacg cttgtttttt cgcttgatgc
    39001 tagcaatatc tggccagcct tcacgcaaga tacggcgaag gacagcgttg accaattttt
    39061 cactgccttt tttacggagt ttggccaatt ccactgcttc attgaccaca gcatgatctg
    39121 gaatcttgtc caaatagcgg agttggtagg cactcatgag aagaaggaca tagagccagc
    39181 tgtctaactg gtctctgtct tcgataaagt gggataggta ccattccaga gtcagtttaa
    39241 gggctaccgt tccatagact agctcggtca ctaagccctt gtctgctgca gagagctgac
    39301 tccccttgag gtgtttattt aaggcaatat ttgaatatgc ttgattcaca aaaacatcct
    39361 ctagcactgc tagagctaaa cttctagccg tttctacttt agtcaccaaa tcgttctcct
    39421 acagtcaatg tacgtccaac tccgttgagg aaggaagcaa tgtccatctt aggcttacca
    39481 gctggctgca cttgtttgag ggatagagcc ccttcagccg ttgcgacaat caattctttc
    39541 ttgcagatag agagaatctc acctggattt ccctgacctt ctactggtag ggcttcataa
    39601 atcttaaagc ggtcgccctt aaggaaagta tgggcaacag gccaggggtt cattccacga
    39661 atttggttaa agagttgacg attggttttg ttccagtcca gtttttcttc ctctggcttt
    39721 atatttggag agaaggtaac ctgactcgta tcctgcggtt caggtttgat atcaccagca
    39781 atataggcag gcagagtgtc caaaagcaaa tcacgaccaa ctagcgccaa tttttcaaac
    39841 aaggtgccaa cattgtcctc atctgtgatc ggaatgctgc gacgagaaat catatctcct
    39901 gcatccattt ccttaaccat ttccatgatg gtcacaccag cttcctcatc cccttgaatc
    39961 aaggcataat ggataggcgc accaccacgg tgtctaggaa ggagggaggc atgaacgttg
    40021 acagcaaagt ccatgctatc aaggagtttg cttgggagaa actgcccaaa agcagcagtc
    40081 acaattccat ctgctcctag cttcataagt tcttccatct ctggacttcc agataatttt
    40141 tcaggttggt agatagatag tcctgcttcc ttggcagcct gcttgactgg ggtttcttgg
    40201 ataacttttt tacgaccaac agcacggtct ggctgggtca caacggctag aatttcgtaa
    40261 cggtcatctg tcaaaagtcc ttttaagact gttgctgaaa agtcgggggt ccccataaag
    40321 attagttttg tcatatcttc tccttcttat aaaaattgct gcggctcatg gtcaatgctg
    40381 agacggagct cactattttc ccgttcttga gtcaaggcta aaacctggtt gagggtcggc
    40441 cccagctcat cttctaaacg gtatttaatt aaaatctggt aatgatagag gttgtgggta
    40501 cgggcaatcg gttttggcgt tggccccaga atgggactgg tctctgacaa gcctgaccgc
    40561 aaaatgttca tgacttcata ggcacgtttg aaaacctctt cttctttctt gtgagaaagg
    40621 gtaataccaa tcgtgaaata gtaaggtgga tagccgagtt gtcgtctgat tcccatttca
    40681 taggcataaa agccttcgta atcttgatcc ttggcaaatc gaatagcata gtgctgcgaa
    40741 ttgtaggact gtatcaagac ttgacctgct ttttcagccc gacctgctcg acctgccacc
    40801 tgagtcaaga gctggaaggt tctctcagaa gaacggaaat caggcagatt caaggccgta
    40861 tccgcattta gaactccgac tagggtaaca ttgggaaaat ccaaaccctt tgcaatcatc
    40921 tgagtaccaa gtaaaatatc cgcttcccct cgcccaaact ggtcaagcaa ggcttggtga
    40981 ctgcctttct ttcgagtcgt atccacatcc atcctcaaaa tgcgagcttg gggaaagagt
    41041 tctgctagct catcataagc cttctgagtt cccgtcccat agtaacgaat actgcggctc
    41101 ttacagttag gacagacctg aggaatatcc ttcgagaaac cacaataatg gcagttcata
    41161 gtcttggtat ccatatgcaa ggtcagagaa atatcgcagt tgggacaagt atccaccgtc
    41221 ccacactccc gacacatgac aaagctagaa taaccacggc gattgagcat gagaaccacc
    41281 tgctcttttt taaccagacg gtcttggata gcctctagca aaggaggcgt aaagtttgac
    41341 gtctcatttt gtccgatata gtctcgaaag tcaatcactt gaacctcagg gattgtagcc
    41401 aaaggattgg cacgttgggt tagacgtaag tgttgataga cgcctttgcc agcacgtgcc
    41461 cggctctcta agctcggcgt tgcagatcca agtaccagag ttgcttgatt atactgagcc
    41521 cgtaaaatag ctacctctct ggcatggtaa cggggattgc tgtcctgctt ataagccgct
    41581 tcatgctctt catcaataat catgacaccc agatttttca gaggagcaaa gatagcagat
    41641 ctggcaccaa caacaacttg ggcatcgcca cgctccacct tgcgccattc atcatacttt
    41701 tcaccattgg ataatcctga gtgaagaatg gctaccttgt ccccaaaacg tgctataaaa
    41761 cgctcggtca tctgaggagt caaggaaatc tcaggtacca gcaaaatagc tgtcttgccc
    41821 ttatccaggg caccttggat aatctgcaag taaacctcgg tcttcccact tcctgtaatc
    41881 ccttgaagta gaaagggagg ttgagaactg ccaatagaac tcacaaccgc atcacgcgcc
    41941 tgtctttgtt ctggatttaa ctccaaaggt ctacttgctt caattccttc aaaataagca
    42001 gccgagcgtt gaacttcctt ttggactatg gtaacagcac cttgatccac aaagaagttg
    42061 acttgctctc gcgagtagga ctctaacaag ctagccaagg aagcgctctc tggatgagac
    42121 agcagataat ctctcagttc caactttttc ttggcacgtg tagaaatctc aacaccttct
    42181 aattgggcat ggtcaacctc ataccaagac tgggtcttga ccttcttttg atcgactgcc
    42241 tgatattcca gaccaagcag gccttttcta gtcaaacgca tcatttcagc ttgcttggca
    42301 aggtctagtg aagaaaaggc tagcgaatct tctgaaccaa acaggcgcac tcgttcttcc
    42361 tgactcaagc cttccagagg atagagaatc ttgtcatagc tagaattcag aaaccctgga
    42421 agcatggcct tgaggataga gattttgtag gagaagacag atttgcgtaa ctcctcagcc
    42481 agccagagtt gttctggcgt gagaacagga gaaaaatcca gcacctctgc aatatctttt
    42541 aaatcttgct ccatctcttc tccatctgat tgggacttca aaccaagaac aatcccttga
    42601 atcaggcgat tacccttacc aaaaggcaca tgaacccgca tcccaacttc cagcattccc
    42661 tcaaattcct ccggaatcct gtaactatag ggctggtccg tctgcatcaa gggcacatct
    42721 acgataatct tagctagggc catcttctca cctcctcctt gtcagcacat tcttgcaata
    42781 gaaaaaataa gattgagtcc ccccaacctt aaattttttc accatcttct ttttctttag
    42841 caatttgctc tttgattttc ttttcttctt cttctttgcg gcgtttttct tcttcgatac
    42901 ggcgacgcac tgcttcacgt tttccttctg gatctgggtg aattgtaacg tttcctgatt
    42961 cgatttcttc taaagcgcga agagttgatt tttcagactt gaaaccttga gttgctgggg
    43021 cacctgcttc caattcgtgg gcacgttttg cttccaagat tacgagtgaa tattttgaag
    43081 gaaccttgtc gagcaaggta tcaatagagg gttttaacat catttgcttg tacctatttt
    43141 ctaaatttta tcgggtagtt ggagattttg gtaacatctc ctgatagtga ccaatgacac
    43201 gatccacaca gaagtgttct gcttcaatca cacatttgac acgttcagca gctaggggca
    43261 cctgatcgtt gacaatcgca taatcatact cacgcatgag ggcaatttct tccttggcct
    43321 tttcgattcg ttgggcaatc acttctgcac tatctgttcc acgacctacc aagcgatctt
    43381 gcaattcatc caaatctggt ggtgtcagga agataaagac agcatctgga acctttttct
    43441 tgacctgaag agcaccctga acttcaattt caaggaaaac atcgattccc ttgtccaagg
    43501 tttcattgac ataggtcaga ggagttccat agtagttacc gacatattct gcgtattcca
    43561 acatctgtcc ttgacgaatc agctcttcaa attcttcacg agtacggaag aaatagtcaa
    43621 caccgtccac ttctccagga cgttgtgcgc gtgtcgtcat cgatacagaa tattgaaatt
    43681 ggttttcaga actctcaaaa atctctcttc taaccgttcc ttttccaacc cctgaaggac
    43741 cagaaaaaac gattagtaag cctcggtctg ccattgtgtc tccttttagt caatctgtga
    43801 aataacattt ctctagaata atggcaaaaa gccagattat cctttacagt ctttctatct
    43861 agtgtaacaa aaaagcagta atttttcaac tgctctttct tatttattta gcataatcta
    43921 ctgcacgaag ctcgcgaatc acggttacct tgatatttcc tggataatcg agattgtttt
    43981 caattttctt acgaactttg tgagccaaga ttgtgacttt gtcgtccttg atttttcctg
    44041 gattgaccat gatacgaatt tcacgtcctg cttgaagggc aaagctagtt tgcactcctt
    44101 caaagccgtt agcaatttct tccaaatcat ggagacgctt gatgtagctt tcaagagact
    44161 cactacgagc acctggacgg gctgcgctca aggcatctgc tgcagcgaca ataactgcta
    44221 tcacgctctc agcttcaaca tctccgtggt gactagcaat cgtattcacc acaactgggg
    44281 gttccttgta cttacgggcc aattccatac cgatttcaac gtggctacct tcaacctcat
    44341 ggtcaatggc tttcccgata tcgtgaagga atccagcacg acgggcaaga gccgcatttt
    44401 caccaagttc gctcgccatg ataccagcca acttagcaac ctcaatcgaa tggcgcaaaa
    44461 cattttgtcc atatgaagta cggaactgca aacgtcccat aatcttcatc aagtctggat
    44521 gaaggtttgg cgcaccaatt tcataggcag cagcctcacc gtattcacga atcttattgt
    44581 caatctcttg acggtttttc tcaaccaact cttcgatacg agctggatgt atacgaccat
    44641 ctttgagcaa catttccata gtcatacggg caatctcacg acgaatcgga tcaaatcctg
    44701 acaaggtcac cacttctggt gtatcgtcga taatcacatc gacccctgtc aaactttcaa
    44761 aggtacgaat gttacgacct tcacgaccaa taatgcgtcc cttcatagta tcgtctggca
    44821 gatgaactgt tgagtttgtt gactccgcta catattcacc agcgatacgt tgcatagctt
    44881 gaaccaagat gtccttggcc attttgtcag aacgttcctt gacctcttgc tcagcttcgc
    44941 gaatgcgact ggcaatctcc ctggtcaagt tttcctctgt ctgagccaag ataatatctc
    45001 gtgcttctgc ctgagacaga gcaccaatac gctctagttc tgcttctttt tgtctttcga
    45061 cttcctctaa ttgctcttca cgcgcatcaa ggtttttcgc tctatcagaa atactttgtt
    45121 ctttttgttc aagtgtttgt tctttactcg tcaaattgtc gtccttacgg tcaaggctag
    45181 tagctctctc tgtcaaacga ctttcgattt gtttgagttc ttgacgttct gatttgaatt
    45241 cagcgtccac ttcttcacgg tattttctgg cttcttcttt ggcctccaat agtgcttctt
    45301 ttttaagaga cttgctttca cgtttggctt cattaacaag taaatccgct tcacgctcag
    45361 cttgtccacg taaattagtt gcttcttgtt cagcatttaa aagcatcaac tctgcagctt
    45421 cctgagatga tttcatctta gctgagatgc tgacatatcc aatgactaaa ccaatgatga
    45481 cggcaaaaac agcaatcgca agcgacatga tttccatgtt tttacctcat tttattgtta
    45541 ttccgaatga catacattct tttacattct accataaaaa agtgattttc acaaacctaa
    45601 aatagaatat gttttgagga atttggaaca catttaccaa aataaacttg ttgtttagaa
    45661 atagtagttt agtagagact tgagaaaaag cctacctttc aatagactta gtaatgatct
    45721 ttaaaggaca agaaagccac gctatctcca tccatcatat aaatcaagcg attttctgca
    45781 tcaatacgcc gtgaccaggc tccttggtaa tcatatttga gtggttctgg tttacctatt
    45841 cctgtaaagg gatcacgttg aatatccttg attagtttat tgattctttt taacgttttc
    45901 ttatcctgat tttgccagta gcaataatct gcccaggcat cttctgtaaa cttgagcagc
    45961 atttcttact cctcaataac atggacctga gtacttccag cacgaacttg agccattcct
    46021 cgcaaaacct tatcagaaag ttccttattt tgagcaattc tcagggtttc ttggatacta
    46081 tcccactcac tctttgaaag gactacaatg tcctcatctg gatttttatt gaccaccgtc
    46141 aaaggctcaa attcatcatt taccttcttc atgtagtcct ttaaatgatt tcggaatgtt
    46201 gagtaaagga ctgcttccat aaccatacct cgttttagct cttttccact attatacacg
    46261 aaaagaaaga aattgtcagg aacttgtaca agattttctt ttctatctat ttatactcaa
    46321 tgaaaatcaa agagcaaact aggaaactag ccgcaggctg tacttgagta cggcaaggcg
    46381 acgttgacgc gatttgaatt tgattttcga agagtattat tcgtaaaaaa tctcaaaaag
    46441 cctacctttc ggtagactta gtttgtttct attctaatcg gcactcttcc aaaattttgc
    46501 tctgctatac ttggcttccc tagttggtaa atctggtctg ctttttgggt catagcatcc
    46561 caaggttctt tgccaattcg gctgactaga ttgacctgtc ctttcagaga cttgagatgt
    46621 tgcctgcctt tttcagtaaa tccaaggaca tgaatggctt ctggcaagac attttctcta
    46681 gcctgcacca aaatataggt caataggcgt ctgacacgcg ccttggtgta acgtttggta
    46741 gtcactaact cgaccaattc ttccacagac tgggctgttt taatagcttc tttaatgcgc
    46801 acagccattt cttgattgac ctgatagatg gtggttaggt cgggatttga caagatttga
    46861 tagcggagca agggaaaata gtcttcccag atcaccttac tggcctgctc aaatagggca
    46921 acagaaggca taaaacgttc taagaaatct tggtccttct gatgttgacg gagggctgtc
    46981 gccgaggcaa agtccacatc tttattcaca gaatggtaac ctgccccctg acgctgaatc
    47041 ggatgcagct tgatatttcg tcctgcaacc gccttggcat aggccagagc aagaacatga
    47101 ttgggggtat tacctgaaaa atcaagacca gcaaattcct tccacatagc ttgggttttc
    47161 tggggatagg aaagggaatc aggcagattt tccacaaatt tctccatctc agcacctttc
    47221 tctgtgtata agtcagcaat tttctgataa tctcgaactt cctctgtccc aaaaactaga
    47281 ctatcaatgc ccaagcgatc caagatatcc atagctcctt gaccaaagaa atcagctgcc
    47341 tgaacactga ctaaaaaggg caattccact accaagtctg cgccattttc cagcgccatc
    47401 tgggtccttg tccacttatc cacaatagca ggctctccac gctgcatgaa attccctgac
    47461 atggcaacaa ttttcagtcc ctctgcctgt tccagcaggt atttatggcc attatgaaaa
    47521 ggattgaact ccgcgataat acctgttatg gtcatgctaa tctcctactt ctgcgccaca
    47581 aaaaaccaac gggtgctagt ttctgttggc tccttatcct caaagtctgc atagagtttg
    47641 aaggacttaa atccagcctg ttccagcaag atatcatagg tcaagatctc ataggtcctc
    47701 tcctcatgta cttcatcgtg gcgactaaag gaaccgtcag cctccttgat aaagaaagtc
    47761 agctcatgca cgatggagtg aggagcttcg tcctcatatg tatcccaaag catggcaaaa
    47821 tcttccgcat tttcatggta ggaatagcca gggaatactt catctgtctg gtaggtcgag
    47881 tgcacgtcaa agatgaaaac tccctcttca ttcagcgcat tgtacacgtc cttaaagacg
    47941 tcccctactt ccacctcatc ctgcatatag cagatagagt ccgaataaca cgtgacaaaa
    48001 tcgtatttcc ctgccttgga caaattcagc atattacctt ctacaaaagc aatcttttgc
    48061 ttggctgaag ttgctctctt ctccgcaatc ttcaacatat ccgcactcaa gtcaagtcca
    48121 gtcacatcaa aaccagcctg agagaagcgc actgattgaa ttcctgtccc acaagccaat
    48181 tccaagagtt tctttctctc cttggtctta ggcaaatgac gcagagaaaa attcgtccat
    48241 ttgtcgtata aactatcgtc catgaccgca tcatagaccg ccgcaaaggt ttcataagtc
    48301 gccataatca tgatactaag agctccatgg taaacaccac tagcccttta cctttctatc
    48361 aatttttcta aaataagcaa agaaacccag ttgactacaa ctgagttcat cttctaagca
    48421 agagcttctg aaatatctac tgaattcgcc tcatgccata gcttctctag attataatgg
    48481 gcacgcattt cttctgaaaa gatatgcacg acaacagcac cgaggtccag taagacccag
    48541 cctccagctg catcgccttc gacatggcta cctttaaagc ctgcttgagc tactttttca
    48601 cggatattag ctgcgatagc gtccagctga cggctattca ttgagctagt gatgacaaag
    48661 tagtccgtca cactagtcaa atcttgtaca tcaagtgcga ggatatcctc cgcacgtttc
    48721 tcatcagccg ctttcacgac tagttctagt aattcttttt cgttcattta atcctctttt
    48781 tagaaaatat gtttgtaatc taggacatct gcaaagcgct cctcccaaat gtcctcataa
    48841 aattcattaa tcgtttctgc tggaatgtca tccccatcaa aggttgtgac agcaccttct
    48901 ggaacaataa gctgatagcc atattcaaag gcaatcttga cagaggtatc cacacaatat
    48961 tctgtctgca taccacataa aactaatttt tcaatcccct gcttatccaa gtattctttt
    49021 aagccagttt ctttgaaaat actgttatat ttcttctgaa agaccttttc agcaggtttt
    49081 cgatttaaaa gcgcagataa ctgccaatct tctgatgttt gagcttcaga gttctcaata
    49141 tgttgaacat agataatttc aatattcttg cttctagcct ggttttgtaa ataagaaatt
    49201 ttttccaata gactttttgt ctggaaccca gtttctacta aaacattctg aacatcaatg
    49261 attataaaag ccatcttcat ttagttctct ttcaaatagt gcacaaaggc gttataggtt
    49321 tcaagggttt ggggatagat ggggaatccc tgatgagcta gatactccac ggtacgagct
    49381 gtttcgtagg ccaccgcctt attgagcgat agacttgcaa cctcacgcgc cacatctact
    49441 ccaggaaagg atcgattgtg ctcgatatag tctgctacat agacaacctt atctaggtct
    49501 gtcatctgac cagcaccgac tgtatggact tcaatggctc gcaggatttc tgaatcatgc
    49561 aaatccaaat cttcctgaat tttgtaaatt ccgaccatac catgccagac attattgccc
    49621 cagtttttga ggtcagggtc tagctggtaa cggtcaatca agtctagaaa ttcctgatct
    49681 gacaactttt tagcatagtc atgaagaaga cctgctagac ttgctttctc aacatctaca
    49741 ccaaagcgct gagctaattc catagcggca cgctccacac ctagacaatg ggttagacgt
    49801 ttctcaggta gaagctctgc cattttttcc aacaaggcct cacgggagca gttgatatag
    49861 tcttgatagg acatcagtag agcccctcct tctcgatgta gtctagcact ggctgaggta
    49921 agagaaagtt gggtttccga ccttgggcaa tgaagtcccg caccatgctg gacgagatat
    49981 ccatgagcgg tacgtccacc cagataactg gataggaagt ccctaccttg tagcgtggac
    50041 gctgaacccc cacaaactga accatgtcaa ccagttcatc aattcggtac cacttaggca
    50101 gatagtcaac catgtcggca ccgatgataa agtaataatc cgtatctgga ttcttctctg
    50161 tcaaaatctt catggtgtcg taggtgtagg aaataccctt gcgctccaac tcaatggttt
    50221 caatgactag gccgtcaatt ccctcaattg ccaactcaag catcttgaga cgatggtgtt
    50281 cagggatggt ttccttttta tcaacgtgag gaggttggta ttcaggcatg agcagaactt
    50341 gatccagtcc caactgttgc cgtacttgat ccgcaacaat gagatgggca ttgtgaacag
    50401 ggttaaaatt cccccctaaa atcccaactt gtttgcgttt tttctccttg atttctggct
    50461 ccaactctac cttggtaaag ggagtcaata gttcgattgt cataggctag tcccctttat
    50521 ttctctataa aaacagttat ttggagtttc gatcttagat ttctttgact ttcttagaaa
    50581 tcttgcgatt ttctttcttg ctagattgtt taaacaaaat caagatgcgt cctatttttt
    50641 ggactgtatc tacaccgatt tcttcttcca aaatttcagc tacttcgtgg atgttttcat
    50701 ctgtgttttg taagagagta accttgatta attcacgcgc atcaagagct tgacggacgc
    50761 tggttttgat ttggtcgttg agtccatttt tcccgatttg gatgataggt ttgagggtgt
    50821 gtgcctggct gttgaggaag gcacgttgtt ttgatgttaa tgacataatt ttcttccttg
    50881 ttttttgata gttattttag gtggtgaggg acggtcggaa ctaattttcc aaagatttca
    50941 tctttgaaaa atggatttcc tgacctcaca attgagcctt ggtctcaatt gtgccccttg
    51001 ccaatctaca gattggcaat cacaccacgg caataactat cgctatatga gctcactttg
    51061 ttcgctcagc gattttgttt taaataattg cttttcgtgt aacgacggcg acgccttctg
    51121 gtgcccagac ggcgactttt gctgtgcctg ttacacgaat ccagcctagg cctgagatga
    51181 ctaggtctgt cttatcttta atggtaaaga catgctggac tagccttggg aaatcttctt
    51241 tttccttgct atttggtggt gtcagaagag ttcccaggtg cttatcgtag aaagcactag
    51301 ctccttcaag cttgctacga tggagtttga gttcattatc aaagaaagca gtaaatcctt
    51361 gcttttctcc tgctataaag tcaaagcgtc ccaaaccacc taaaaatagg gtttgctcag
    51421 gattaagctg ataggtctta ggcttgattt cctttttagg actgacatac ttgaggtttt
    51481 tggccgtcaa gtagtgagcc atctggtggc ggtggataat tcccggcgta tcgtaaatat
    51541 aagatccgtc gtcaagcgga atctctattt tgtccaaggt tgtccctggg aagcgtgaag
    51601 tagtgatgac attctgatca cccgtgattt cttggataat agcattgatt agagttgatt
    51661 ttccaacgtt ggtcacaccg accacataga catcgcggcc cttacggtag tgttcaatct
    51721 tgtcaatgac ttccttaatg gcatatttat tttgtgctga agttaggacc acatcgactg
    51781 gacgaagacc ttcttcatgg gcacgtttca tgagccactg gctaatctta ccagacttaa
    51841 ctgacttagg aaggatatct tttttatttc ctaccaagag gacatcattg cccgagacga
    51901 aacgtggtaa acctgggatg acagatccat taaaatcaaa gatatcaata acattgacca
    51961 ctaaagcatc actgtctccc acctcgtgca agagcttgag gaaatcatcg ttcgtcaact
    52021 ggacatctgt gatttcattg tagtggcgga gacggaaaca gcgttggcaa tagacttcgc
    52081 cagtctccaa acctttttca agtgccgact ggggggtaaa accaagacca gctttatctg
    52141 tcgtctgaat ggttgctcca caaccaatac agagaatttc ttccatagtt aaattccttt
    52201 tttatatgta atcggtccgt acttttcagt gatttttctc ataacacgac gctcacgagt
    52261 tcggttaatc tgcgttttga ttgagtcatg ttggaccaag ggtttgacta aaattgaccg
    52321 aatccctgca cggtgggctg ctcgtatatc tgtcatgagc tggtcaccaa ccatgaccac
    52381 ttcctttttg tcatagtgga attccttcat agcacggtca ataccaaatg tgaagggctt
    52441 caaggcccag taaacgtaat caatcccaaa tttctcaact gctcgttgaa cgcgtttttt
    52501 ggtgttattt gacactacga taatgccaat acccgcgtcc cgaaggtcat gtagccattg
    52561 cttcatctct ggcgttccat cagggttgtt ccaagcaatg agggtattat ccaaatcgac
    52621 caaaacagcc ttgattccct gcgcctgcag gcttgggact gtcagatcat agactgcttc
    52681 cacagcaaaa tctggtatat aattttcaat cgccattctg gctccttttc ttaacttttt
    52741 ttcgcaattt tccttagtaa caaggataaa acaatccaca aacctgcact agccaaactg
    52801 atatagagcc aagcatgggg ctcatctgtt aaaggtaagg gaacattcat tccgaaaaag
    52861 cctgtcacga ctgccaaaac agctagcaag actgaaatga tagtcaaggt tgtcaaattg
    52921 tcattcagat tattgtttag aatattgttg taagaggctg aaagctgctg taaaatctga
    52981 gagattaggt ctgtcatgga taccagctga tgagcctcaa tcatggcatc atcaaactgt
    53041 tctctctcaa tctcatcaaa actacgatac aaggcatgac cttgaatatg ctctaacaaa
    53101 atccgatttt gtttggcagc tgccgttaga taaaccatac cagtctccaa atcagacagg
    53161 gcaaagaggt ttttcttggt agttcgctgg cgcaagaggt cattgacctc atccctactc
    53221 ttgtccatct gctcaatgac aggatagtag gcattgctga taatttccag actggcaaag
    53281 agaaacttat aaatcgaaag cgtgtcatgg ctctccagat aacgagtcat ctgttcaatg
    53341 acataggcgt tcttggtatt actaatggta atcaggcgac gatgctcgac aataaaggtc
    53401 atgggaaaag tctcatagta ggccttgtcc ttttttacgt ctaggacatt atagataaag
    53461 gtaaccgtcc cactttcacg gtggtaatcc atgtgggcgc gctcgtttct atccagtgcg
    53521 tattcaatgg tttccttgtc caaaccgtaa atttcagaaa ggtcttctag tttattcaac
    53581 ttccctaggt ctaggtctat ccaggtacaa ccattgccca actgcttttc taaaaccatc
    53641 ttttctcctt attaaactcc ctctattgta ccacaaatta cttaaaataa caggtctagt
    53701 ctgtgcgtga gaaattgcta acaactgtga tatttcggtt agggacaaag tgaagggctt
    53761 gctcctcgct acgaagctgt gtcgtacgaa ttcccacact gacaacctta cccgatacag
    53821 taatcggtcc atttgtcaga acgacctcat ctcccacatc cagttgacgt tcaaagagga
    53881 tgaaaaagcc attgatgaca tcagacagaa agccttgggc tcccatacca atcgctaccc
    53941 cagcaatacc agctccagcc agcaaactag aaactggcaa acctaaaata gacaaaatgc
    54001 agtagagtaa aaagaaatat agcgtataat taaacacatt ttctagtaaa cgtgagatgg
    54061 ttttttggcg tccgacatca tgacgagaca tttttagaga aggtttgaca attctctgca
    54121 ccatggtatg aagcattttt ttagcaatat aaaatacaat caaaagcagt aaaagagaaa
    54181 tgaccttggt tagaatattc tcgataatgg ttgtcacatc tagcttttca atataagcct
    54241 gaataaattt ttgcatataa aactccttta tttcattata ccatattttc atcagtctca
    54301 ttctccataa atattcaaaa aatagacaga aaattcttga ttttgtctat catttatact
    54361 ataatcataa tcactacaca aaaaggagat tattatgaaa agaatcattc atgcttggaa
    54421 taaggcaagc cttgtcaagc gtatcttgat tggtatgctt tgtggggaat cctaggactg
    54481 acccttccta atctctcagg gattgggcta ctcggggatt tattcgttgg aggtctgaaa
    54541 gctgttgctc ctatcctagt ctttgccctc gttgccaatg ccctttccca acatcaaaag
    54601 ggacaagata gcaatatgaa aactgttgtt ttcttgtata tcctatgata gggactttcg
    54661 ccgctgctct tgtagctgta ctagcaagtt tcatcgtccc tattgaaatt accctaaata
    54721 gtgccaatac tgaaattgca ccaccagatg ggattgggca ggtcctcagc aacctcttgc
    54781 tcaaactggt tgacagccca gtcaacgccc tgcttactgc taactatatt ggaatcttat
    54841 cttgggcagt catttttgga atcgctatga gagaagctag taaaaatagt aaagaattgc
    54901 taaaaactat cgctgacgtg acttctaaaa ttgtcgaatg gatcatcaat ctggctccat
    54961 ttggaatcct tggtcttgtt tttaaagcca tttctgacaa gggagtcgga agccttgcca
    55021 actacggtat tttattggtt ccattagtaa cgactatgct ttttgttgcc cctgtggtca
    55081 accctttgat tgccttcttc tttatgagac gcaatcctta ctctctagtt tggaactgcc
    55141 tccgtgtcag cggtgtgaca gcctttttca ctcgtagttc tgcgactaac attcctgtca
    55201 acatgaaact ctgccatgac cttggactca acccagatac ctattctgtt tctatcccac
    55261 tcggttctac tatcaatatg gctggagtag cgattaccat taaccttttg acccttgctg
    55321 cagttaacac tcttggaatt cctgttgact ttgccacagc ctttgtcctc agtgtggtag
    55381 cagctatctc atcctgtgat gcttcaggta ttgccggagg ttccctcctt cttatcccag
    55441 ttgcttgtag ccttttcggt atttctaacg atattgccat acaaattgtt ggggttggtt
    55501 ttgtgattgg tgtcatccaa gactcatgtg aaacagccct taactcttct acagatgtcc
    55561 tctttaccgc cgttgccgaa tacgcagcaa cccgtaaaaa ataactcatc aaggcaagcc
    55621 tgctcatgtc ttgtctttta cgcttttatt ctaacttatt aggaaattct tatgtctatt
    55681 agccaacgta cgaccaagct catcttagct acctgtcttg cctgcctgct tgcttatttt
    55741 ctcaatcttt cgtcagcagt ttcggctgga attatcgctc tcttgagcct atctgatacg
    55801 cgtagaagta ctttaaaact ggctcgcaat cgtctttttt ctatgcttct agctctggct
    55861 atcggtgttc tagcttttca cttgagcgga tttcatatct ggagtctcgg cctctatctg
    55921 gccttctacg ttcctttagc ctacaagatg ggctgggaaa ttggcatcac accaagcact
    55981 gttttggtta gccatctctt ggttcaagag tcaacctctc cagaccttct agtcaatgaa
    56041 ttccttctct ttgctattgg tacaggattt gccttgcttg ttaatctcta tatgccttca
    56101 cgagaagagg aaatccagca ctaccacacg ctggtggaag aaaagttaaa agatatcctc
    56161 cagcgcttca aatactattt atccagagga gacggacgca accgagcaca gctggtagca
    56221 gaattagaca cgcttttgaa agaagccctc agactggtct atttggatca ctctgaccac
    56281 ctctttcacc agaccgacta ccatatccac tactttgaga tgagacagcg acaaagtcgt
    56341 atcctgagaa acatggccca acagattaac acttgtcacc ttgccgccag tgaaagcctg
    56401 atcttagcgc aactcttttc aaaaattgca ggtcaactga gccagaccaa tcctgcttct
    56461 gatttgctag atgaaattga acgttatctg gaagtcttcc ggaaccgcag tctgcccaag
    56521 acaagagaag aatttgaaac ccgcgccacc cttcttcaac tcctacgtga agccaaaacc
    56581 ttcatccaag taaaagttga tttttaccaa aaatatagac agtaaaaaat aaaaccacta
    56641 aaaaacagag cttgccagca ttcttgaaaa gtagtataat tattgcatgc gcaatcatct
    56701 tgtgacgcag agactgcccg ttaatggact ttcttctatt tatgactcta aaaagaaagg
    56761 agacactatg acctatttgg aaaaatggtt tgacttcaat cggcgtcaga aagaaattga
    56821 aagtctcttg gaagagaccg ttgcccaaca gagcgagcaa agtctgacct tgaaagagtt
    56881 ctacctgctc tactatctgg acttggctga agaaaaatct ctacgccaga ttgacctgcc
    56941 agataagctt catctgagcc cgagcgcagt ttctaggatg gtggctcgct tggaagctaa
    57001 aaattgcggt ctactcagtc gcatgtgttg ccatcaagat agacgctcta gttttatctg
    57061 cctgacaaat gatggacaaa agatactggc ctcgctacaa aagactgtcg aagaaagctt
    57121 ggaagcaggt ttggatttct tgatttaaga tgattttaga aaaagttgcg tgcgcaatca
    57181 tttttcttga cattctcttt tataaggagt aaaataaagt tagcattaaa caaaggagtt
    57241 ttaaatatga ttgaaattac ctatatagat gccagcaaga acgaaagaac tgtgactttc
    57301 gagtcttatg aagactttga acgttcgcaa caagcttgcc ttatcggcgt cgcagactac
    57361 taccctgtcc aaaaattaac ttacaagggt cataatttgg actaccatgg gacttatgga
    57421 gatatcttct tctatctcat gaaacaagat ttaagccaat ataactaaaa aaaggagaaa
    57481 tacaatggca aaagcaatta cagatgcaac attcgaacaa gaaacaaaag acggtttggt
    57541 cttagtagac ttctgggcaa cttggtgtgg tccatgtcgt atgcaaggtc caatcttgga
    57601 caaattgtct gaagaacttt cagaagatgt cttgaaaatc gttaaaatgg acgttgatga
    57661 aaatccaaac acagctcgtg cttttggaat catgtctatt ccaactcttc tcttcaaaaa
    57721 agacggccaa gttgtcaaac aagttgcagg tgttcacaca gcagaacaaa tcaaggccat
    57781 cattgctgaa ttgagctaat caaacgagag accaagtact ttctttggtc tcttttttct
    57841 tgccctttgc catttttcaa aaaatatgct agactatagc agattgaaac tagaatagta
    57901 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttatcctg
    57961 ttcttatttc attttactat ataagtagaa tattacgatg tttgggatat gccatcgcta
    58021 aaaaaaaact cgatttggta ttttttagct ccctaatggg agctttttgc atgctctgaa
    58081 catttcccat tttggaagga gtactatgaa acgtcaatta gccttggtcg tctttagtgg
    58141 tggtcaagat tcaacaacct gccttttctg ggtcatgcaa cactatgaaa cagtcgaagc
    58201 tgtcaccttt gcctacggcc aacgtcatca cctcgaaatt caaattacta gagaaatcgc
    58261 taaggaacag ggcattcgtc accatatcct cgatatgtct ctgctgggac aaatcactgc
    58321 tcagccagac tttgcgacga ttcatatttc ctacattcct gacaagctct gtgtcgagtc
    58381 aaaatccctc aaactatatc tatttagcta ccgaaaccac ggagatttcc acgaaaactg
    58441 tatcaacacc atcgggaaag acttggtcaa cttgctagac cctcgctatt tagaagtctg
    58501 gggaaaattc actccgcgcg gtggcatttc aatcgacccc tactataact acggtaagca
    58561 aggaactaag tatgagggct tggcagaaca acgcctcttc caacacgacc tttatccaga
    58621 gaaaattgac aaccgctaaa gtcatactca atgaaaatca aagagcaaac taggaagtta
    58681 gccgcaggtt actcaaagca gtgtttgagg ttgtagataa aactgacgaa gtcagctcaa
    58741 aacactgttt tgaggttgca gatagaactg acaaagtcag cttaaaacac tgttttgagg
    58801 ttgcagatag aactgacgaa gtcagcttaa aacactgttt tgaggttgca gatagaactg
    58861 acgaagtcag cttaaaacac tgttttgaag ttgtagatga aactgacgaa gtcagcttaa
    58921 aacactgttt tgaggttgca gatagaactg acgaagtcag cttaaaacac tgttttgagg
    58981 ttgcagatag aactgacgaa gtcagct
//
LOCUS       DAVLZS010000009        48324 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLZS010000009 DAVLZS010000000
VERSION     DAVLZS010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.009"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            1..1133
                     /locus_tag="VYO88_000550"
                     /pseudo
     CDS             1..1133
                     /locus_tag="VYO88_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1178..1819)
                     /gene="plsY"
                     /locus_tag="VYO88_000551"
     CDS             complement(1178..1819)
                     /gene="plsY"
                     /locus_tag="VYO88_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1718707.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1955..3898
                     /gene="parE"
                     /locus_tag="VYO88_000552"
     CDS             1955..3898
                     /gene="parE"
                     /locus_tag="VYO88_000552"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1718708.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLVAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            4318..6789
                     /gene="parC"
                     /locus_tag="VYO88_000553"
     CDS             4318..6789
                     /gene="parC"
                     /locus_tag="VYO88_000553"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1718709.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSNYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6919..7941
                     /locus_tag="VYO88_000554"
     CDS             6919..7941
                     /locus_tag="VYO88_000554"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1718710.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7997..8701
                     /locus_tag="VYO88_000555"
     CDS             7997..8701
                     /locus_tag="VYO88_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1718711.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8766..9455
                     /locus_tag="VYO88_000556"
     CDS             8766..9455
                     /locus_tag="VYO88_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1718712.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            9452..10375
                     /locus_tag="VYO88_000557"
     CDS             9452..10375
                     /locus_tag="VYO88_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1718713.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            10390..11034
                     /gene="pcp"
                     /locus_tag="VYO88_000558"
     CDS             10390..11034
                     /gene="pcp"
                     /locus_tag="VYO88_000558"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1718714.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            11202..11432
                     /locus_tag="VYO88_000559"
     CDS             11202..11432
                     /locus_tag="VYO88_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1718715.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGNKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            11482..11562
                     /locus_tag="VYO88_000560"
     tRNA            11482..11562
                     /locus_tag="VYO88_000560"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11516..11518,aa:Tyr,seq:gta)
     gene            11572..11643
                     /locus_tag="VYO88_000561"
     tRNA            11572..11643
                     /locus_tag="VYO88_000561"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11604..11606,aa:Gln,seq:ttg)
     gene            11805..13007
                     /gene="rpsA"
                     /locus_tag="VYO88_000562"
     CDS             11805..13007
                     /gene="rpsA"
                     /locus_tag="VYO88_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1718716.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(13092..14341)
                     /locus_tag="VYO88_000563"
                     /pseudo
     CDS             complement(13092..14341)
                     /locus_tag="VYO88_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            14535..15032
                     /locus_tag="VYO88_000564"
     CDS             14535..15032
                     /locus_tag="VYO88_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1718717.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            15032..16687
                     /gene="dnaX"
                     /locus_tag="VYO88_000565"
     CDS             15032..16687
                     /gene="dnaX"
                     /locus_tag="VYO88_000565"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1718718.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTNLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKSEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            16715..16909
                     /locus_tag="VYO88_000566"
     CDS             16715..16909
                     /locus_tag="VYO88_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1718719.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            17059..17829
                     /gene="sufC"
                     /locus_tag="VYO88_000567"
     CDS             17059..17829
                     /gene="sufC"
                     /locus_tag="VYO88_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1718720.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            17857..19119
                     /gene="sufD"
                     /locus_tag="VYO88_000568"
     CDS             17857..19119
                     /gene="sufD"
                     /locus_tag="VYO88_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1718721.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            19130..20356
                     /locus_tag="VYO88_000569"
     CDS             19130..20356
                     /locus_tag="VYO88_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1718722.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAIEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            20343..20783
                     /locus_tag="VYO88_000570"
     CDS             20343..20783
                     /locus_tag="VYO88_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1718723.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            20837..22249
                     /gene="sufB"
                     /locus_tag="VYO88_000571"
     CDS             20837..22249
                     /gene="sufB"
                     /locus_tag="VYO88_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1718724.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVVLEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(22480..23721)
                     /locus_tag="VYO88_000572"
     CDS             complement(22480..23721)
                     /locus_tag="VYO88_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1718725.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            23824..24933
                     /locus_tag="VYO88_000573"
     CDS             23824..24933
                     /locus_tag="VYO88_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1718726.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            25579..25926
                     /gene="ssrA"
                     /locus_tag="VYO88_000574"
     tmRNA           25579..25926
                     /gene="ssrA"
                     /locus_tag="VYO88_000574"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(26109..26196)
                     /locus_tag="VYO88_000575"
     tRNA            complement(26109..26196)
                     /locus_tag="VYO88_000575"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(26160..26162),aa:Ser,seq:gga)
     gene            26358..27098
                     /locus_tag="VYO88_000576"
     CDS             26358..27098
                     /locus_tag="VYO88_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1718727.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSIKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            27095..28006
                     /gene="pfkB"
                     /locus_tag="VYO88_000577"
     CDS             27095..28006
                     /gene="pfkB"
                     /locus_tag="VYO88_000577"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1718728.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINIKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            28003..29955
                     /locus_tag="VYO88_000578"
     CDS             28003..29955
                     /locus_tag="VYO88_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1718729.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            30119..32344
                     /locus_tag="VYO88_000579"
     CDS             30119..32344
                     /locus_tag="VYO88_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1718730.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(32543..32968)
                     /locus_tag="VYO88_000580"
     CDS             complement(32543..32968)
                     /locus_tag="VYO88_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718731.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQPNTPTSENNTQ"
     gene            33106..34248
                     /locus_tag="VYO88_000581"
     CDS             33106..34248
                     /locus_tag="VYO88_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1718732.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            34257..35471
                     /gene="thiI"
                     /locus_tag="VYO88_000582"
     CDS             34257..35471
                     /gene="thiI"
                     /locus_tag="VYO88_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1718733.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            35606..36430
                     /locus_tag="VYO88_000583"
     CDS             35606..36430
                     /locus_tag="VYO88_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1718734.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDEIYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            36452..37191
                     /locus_tag="VYO88_000584"
                     /pseudo
     CDS             36452..37191
                     /locus_tag="VYO88_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            37204..38370
                     /locus_tag="VYO88_000585"
     CDS             37204..38370
                     /locus_tag="VYO88_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1718735.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            38878..40371
                     /locus_tag="VYO88_000586"
     CDS             38878..40371
                     /locus_tag="VYO88_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1718736.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTSRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            40384..41436
                     /locus_tag="VYO88_000587"
     CDS             40384..41436
                     /locus_tag="VYO88_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1718737.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAY
                     GGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLV
                     FLLELMKVIDFSKFADFSGQPKITQKPLENQKYILLPLALQNEFADFVALVDKSQFAC
                     EIAIKVWRNSLKFSII"
     gene            41466..44816
                     /locus_tag="VYO88_000588"
     CDS             41466..44816
                     /locus_tag="VYO88_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1718738.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDNDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIALDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            45087..45164
                     /locus_tag="VYO88_000589"
                     /pseudo
     CDS             45087..45164
                     /locus_tag="VYO88_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(45402..45872)
                     /locus_tag="VYO88_000590"
                     /pseudo
     CDS             complement(45402..45872)
                     /locus_tag="VYO88_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
     gene            complement(45889..48162)
                     /locus_tag="VYO88_000591"
     CDS             complement(45889..48162)
                     /locus_tag="VYO88_000591"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1718739.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYTNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT        14695 a         8647 c        10615 g        14367 t
ORIGIN      
        1 tcgttacgga atagagttcg tcaaaaaagg aaaaaatcgt tactattctc ctgatttaaa
       61 acaagaaatg attcataaag tctgacatga aggctggact aaagatagag tttctcttga
      121 atacggtctc ccaagtcgta cgatacttct taactggcta gcacaataca ggaaaaacgg
      181 gtatactatt gttgagaaaa caagagggag agtacctgag agcggaaaat gccatcctaa
      241 aaaagttaag agaactccga ttgaaggagg aaaaagagaa agaagaaaga cagaaattgt
      301 tcaagaatta atgactgagt tttcgttaga tcttcttcta aaagccatta aactagctcg
      361 ttcgacctac tactatcact tgaaacagct agataaacca gatacggacc aagagcttaa
      421 agctgaaatt caatccattt ttatcgaaca caagggaaat tatgcttatc gtcgaattta
      481 tttagaacta agaaatcgtg cttatctggt aaatcataaa agagttcaag gcttgatgaa
      541 agtactcaat ttacaagcta aaatgcgaca gaaacgaaaa taaaggagac gttggtaaga
      601 aggcagagaa tctcattcaa ggccaatttg aaggctctaa aacaatggaa cagtgctaca
      661 cagatgtgac tgaatttgcc attccagcaa gtactcaaaa gctttactta tcaccagttt
      721 tagatggctt taatagcgaa attatcgcct ataatctttc aacttcaccc aacttagaac
      781 aagtacaaac aatgttggaa caggcattca cagagaagca ctacgagaat acgattctcc
      841 atagtgacca aggctggcaa tatcaacacg attcttatca tcagtttctt gagggtaagg
      901 gaattcaagc atccatgtca cgcaagggaa acagcccaga caatggtatg atggagtcct
      961 tttttgggat tctgaaatcg gaaatgtttt acggttatga gaagtcgttt cagtcgttta
     1021 agcaattgga acaagctatt atagactata ttgattacta caacaataaa cgaattaagg
     1081 taaaactaaa aggacttagc cctgtgcaat acagaactaa atccttcgga taaattaatt
     1141 gtctaacttt tggggtgcag ttcacagaac tggcatttta ttttttagga tcttgatggg
     1201 ttaagttcaa tccccaaggg accaaatttt cagttttatt tttgatacga gctatattgt
     1261 ccttatgacg aatgataatc aaactagcaa gtgctaagat aatagcgatg aagagagagt
     1321 catagttact caggataaaa ccaaaaagtg gaaagagcag aaccccgata acagccgcga
     1381 tcgatgctgt gacactagac agtgaaatca tactgccaag atagagagct ccaaagaaga
     1441 taatcgcaag gtagagacag aagataggcg caaatccgaa aattactcca gcactggttg
     1501 cgacagcctt accaccttta aatcctgcaa agatagggaa ggtatggccg ataacagcca
     1561 aaagtccaaa gatgagagga gaaacgcctt gtagatgaaa aataatcgga agcagcgttg
     1621 ctagggttcc tttgaaaaag tcaatcacaa aggttgccat accagctttc ttacctaaaa
     1681 tgcggaaggt attggtcgtt ccagtgttac cagaaccatg ctcgcgtaga ttgatttgaa
     1741 agaatacttg tccaatccag agaccagatg gaatcgaacc cagcagatag gctaggatta
     1801 ataaaactat tgtaatcata ctcctattat atcatgaatt gggaaagaaa agcagagaat
     1861 ctctgctaaa attgtcacat cggagaaaga aaaattttgc aaaatccttg gaaaacctgt
     1921 agaatagtaa agatgaacga ataggaggtt ccttgtgtca aaaaaggaaa tcaatattaa
     1981 caattataat gatgatgcta ttcaggtgct agaagggttg gatgcggtcc gaaaacgtcc
     2041 agggatgtat attggatcga ccgatggcgc tggtcttcat cacctagttt gggaaatcgt
     2101 tgataatgca gtcgatgaag ccttgtctgg gtttggtgat cgtatcgatg taaccatcaa
     2161 taaagacggt agtctaacgg ttcaagacca tggacgtggg atgccgacag gtatgcacgc
     2221 tatgggaatt ccaactgttg aggttatctt taccattctt catgccggag ggaaattcgg
     2281 tcaaggtggc tataagacat caggtggact tcacggagtg ggttcttccg ttgttaacgc
     2341 cctttctagc tggttagaag ttgaaattac ccgtgatggc gcagtttaca agcaacgttt
     2401 cgaaaatggt ggaaaacctg tcacgacttt gaagaaaatc ggtacagcac ccaagtctaa
     2461 aacaggcacc aaagttactt ttatgcctga cgcgactatc ttttctacga cagatttcaa
     2521 gtacaatacc atttcagagc gccttaatga atcagccttt ctcttgaaaa atgtgacctt
     2581 gtctttaacg gacaagcgaa cagatgaagc gattgagttc cactatgaga atggagtaca
     2641 agattttgtt tcttatctca acgaagataa ggaaatcttg acgccagttc tttactttga
     2701 aggggaagac aatggttttc aagtggaagt agccctccag tacaatgacg gattctcaga
     2761 taacattcta tcctttgtca ataacgttcg caccaaggac ggtggaacgc acgagacagg
     2821 actcaagtct gccattacca aggtcatgaa tgactatgca cgtaaaacag gtcttctcaa
     2881 ggaaaaagat aaaaaccttg aaggttcaga ctatcgtgag ggactagtgg ccgttctttc
     2941 tatcttagtt cctgaagaac acttgcagtt tgaaggacag accaaggata aactaggaag
     3001 ccccctagct cgcccagttg tggatggaat agtggctgat aagttgacct ttttccttat
     3061 ggaaaatggg gaattagctt ctaacctcat ccgcaaggct atcaaggccc gtgatgctcg
     3121 tgaagcagca cgtaaggcgc gtgatgagag ccgaaatggg aagaaaaaca agaaagataa
     3181 gggcttgttg tctgggaaat tgaccccagc ccaatctaag aatcctgcta agaatgaact
     3241 ctatctagtt gagggggact ctgccggtgg ttctgccaaa caaggtcgtg accgcaagtt
     3301 ccaggctatt ctacctcttc gtggtaaggt tgtcaataca gccaaggcca agatggcgga
     3361 tatcctcaaa aatgaagaga tcaataccat gatttatacc attggtgcgg gtgttggagc
     3421 agacttctct attgaagatg ccaactatga taagatcatt atcatgaccg atgcggatac
     3481 cgacggtgcc catatccaga ccttgctctt gacatttttc taccgttaca tgcgtccgct
     3541 agtcgaggca ggtcatgtct atattgccct cccacctctt tataagatgt ccaaaggtaa
     3601 aggcaagaaa gaagaagtgg cctacgcttg gacggatgga gaactagaag aactccgtaa
     3661 acagttcggt aaaggcgcta ccctccaacg atacaaagga cttggtgaga tgaatgcgga
     3721 ccagctctgg gaaacaacca tgaacccaga aacacgtacc ctcatccgtg tcacaattga
     3781 agatttagcg cgcgccgaac gccgcgtcaa tgttctcatg ggagataagg tagaaccacg
     3841 ccgtaaatgg attgaagata atgtcaagtt tacgctagaa gaagcgacag tgttttaatg
     3901 aaagaaaata atatgttagt aaactggaaa ttagagtcgg atgtgaatga ctatgtgaaa
     3961 aagcagtttg aaaatcttgg tttgaaaaaa ttgcaggatt attaatgaag aatctgctat
     4021 gagtgcttat cttaaagagg cgcttaaggg agcggttaag acacaaacta agactaattt
     4081 tggaaaacca gattttcata ttgaaaaata caaacaggat agtttggtta cttatcgtaa
     4141 ctgaacacgg gacgaattcc cgtaaaatat cttttactgc ataaaaacct actctacatt
     4201 ctttgaaagg agttgaacac gccctagata ctgtgtgaaa aagataaatt ctcttgtgag
     4261 tttgcttact tcaagaattt tctattttca cttggtattt tatgggcttt gtatcttatg
     4321 tctaacattc aaaacatgtc cctggaggac atcatgggag agcgctttgg tcgctactcc
     4381 aagtacatta ttcaagaccg ggctttgcca gatattcgtg atgggttgaa gccggttcaa
     4441 cgccgtattc tttattctat gaataaggat agcaatactt ttgacaagag ctaccgtaag
     4501 tcggccaagt cagtcgggaa catcatgggg aatttccacc cacacgggga ttcttctatc
     4561 tatgatgcca tggttcgtat gtcacagaac tggaaaaatc gtgagattct agttgaaatg
     4621 cacggtaata acggttctat ggacggagat cctcctgcgg ctatgcgtta tactgaggca
     4681 cgtttgtctg aaattgcagg ctaccttctt caggatatcg agaaaaagac agttcctttt
     4741 gcatggaact ttgacgatac ggagaaagaa ccaacggtct tgccagcagc ctttccaaac
     4801 ctcttggtca atggttcgac tgggatttcg gctggttatg ccacagacat tcctccccat
     4861 aatttagctg aggtcataga tgctgcagtt tacatgattg accacccaac tgcaaagatt
     4921 gataaactca tggaattctt gcctggacca gacttcccta caggggctat tattcagggt
     4981 cgtgatgaaa tcaagaaagc ttatgagact gggaaagggc gcgtggttgt tcgttccaag
     5041 actgaaattg aaaagctaaa aggtggtaag gaacaaatcg ttattactga gattccttat
     5101 gaaatcaata aggccaatct agtcaagaaa atcgatgatg ttcgtgttaa taacaaggta
     5161 gctgggattg ctgaggttcg tgatgagtct gaccgtgatg gtcttcgtat cgctatcgaa
     5221 cttaagaaag acgctaatac tgagcttgtt ctcaactact tatttaagta caccgaccta
     5281 caaatcaact acaactttaa tatggtggcg attgacaatt tcacacctcg tcaggttggg
     5341 attgttccaa tcctgtctaa ctacatcgct caccgtcgag aagtgatttt ggcgcgttca
     5401 cgctttgaca aagaaaaggc tgagaaacgt ctccatatcg tcgaaggttt gattcgtgtg
     5461 atttcgattt tggatgaagt cattgctctt atccgtgctt ctgagaataa ggcggacgcc
     5521 aaggaaaacc tcaaagttag ctatgatttt acggaagaac aggctgaggc tatcgtaact
     5581 ttgcaactgt accgtttgac caataccgat gtggttgtct tgcaggaaga agaagcagag
     5641 cttcgtgaga agattgctat gctggcggct attatcggtg atgaaaggac tatgtacaat
     5701 ctcatgaaga aagaacttcg tgaggtcaag aagaaatttg caactcctcg tttgagttct
     5761 ttagaagaca ctgcgaaagc aattgagatt gatacagcta gtcttatcgc tgaggaagat
     5821 acctacgtca gcgtgaccaa ggcaggttac atcaagcgta ccagtccacg ttcctttgcg
     5881 gcttccacct tggaagaaat tggcaagcgt gatgatgacc gtttgatttt tgttcaatct
     5941 gccaagacaa cccagcacct cttgatgttc acaagtcttg gaaatgtcat ctacagacca
     6001 atccatgagt tggcagatat tcgttggaag gacatcggag agcatctgag ccaaaccatc
     6061 acaaactttg aaacgaatga agaaatcctt tatgtggaag tactggatca gtttgacgat
     6121 gcgacaacct actttgcagt gactcgcctt ggtcaaatca aacgggtaga gcgaaaagaa
     6181 ttcactccat ggcggaccta tagatctaag tctgtcaagt atgctaagct caaagacgat
     6241 acagatcaga ttgtagcagt ggctccgatt aaactagatg atgttgtctt ggttagtcaa
     6301 aatggttatg ccctgcgttt caatatcgaa gaggttccgg ttgtcggtgc taaggcagca
     6361 ggtgtcaagg ctatgaattt gaaagaagat gatgtcctcc aatctggctt tatctgtaat
     6421 acttcgtcct tctacctctt gacccagcgt ggaagcttga aacgtgtttc cattgaggaa
     6481 attctagcaa ccagccgtgc caaacgagga ttacaagtct tgcgtgagtt gaaaaacaaa
     6541 ccgcatcgtg tcttcttggc aggagcagtt gcagagcaag gatttgttgg cgatttcttc
     6601 agtacggaag tggatgtgaa cgaccaaact ctgcttgtcc aatccaataa aggaacaatc
     6661 tatgaaagcc gattgcaaga cttgaacttg tcagaacgca ctagcaatgg aagcttcatt
     6721 tctgacacga tttcagatga agaagttttt gacgcttatc ttcaggaagt agttactgaa
     6781 gataaataag tgaaatgaag aatcagttct aagatggttt ttattggagg aattttctga
     6841 aaattacaaa atatacttgc tattttagaa aaatagtgta gaatataaga aataggtttt
     6901 tagaataagg agtggaatat gacagtaacg attgattggg aaaacctcgg tttttcctat
     6961 atgaaattac cttatcgcta tcttgctcat ttcaaaaatg gacaatggga tcaaggagag
     7021 cttacagagg atgcaacttt gcatatttca gagtcttctc caagtcttca ctatggacaa
     7081 caagcatttg aaggtttgaa agcttatcgt actaaggatg gcagtgttca actgttccgt
     7141 cctgatgaaa atgctaaacg cctgcaacgt acatgtgacc gtctcttgat gccacaagtt
     7201 ccgacagaca tgtttgtaga agcttgtaaa gcagttgtcc gtgcgaatga agaatacgta
     7261 ccaccatacg gaataggtgg aaccttatat cttcgccctc ttttgattgg tgtcggagat
     7321 attatcgggg taaaaccggc agaagagtac attttcacca tctttgctat gccagttgga
     7381 aattacttta aaggtggttt ggtcccaacc aacttcttga ttcaggatga gtacgaccgt
     7441 gcagcaccaa atggtacagg tgcggctaag gttggtggaa actatgctgc aagtctctta
     7501 ccaggaaaaa tggccaagtc acgccatttc tcagatgtta tctatctgga cccatcaact
     7561 catacaaaga ttgaagaagt cggatcagct aatttctttg gaattacagc tgataatgaa
     7621 tttgtaacac cattgagtcc atctatcttg ccatctatta ccaagtattc cttgctttat
     7681 ttggcagaac atcgcttggg attaactcct attgagggtg atgttccaat tgataatctt
     7741 gaccgttttg tagaggcagg tgcctgtggt acagcagcgg ttatttctcc aattggaggt
     7801 attcaacatg gtgatgattt ccatgtattc tatagtgaaa cagaagtagg tcctgtgacg
     7861 cgtaaattat ataatgaatt gacgggtatt cagtttggcg atattgaagc gccagaaggt
     7921 tggattgtaa aagtagatta aaataaacca aaggagattt tttatgaaat agaaaaagtg
     7981 gctcttaaca gcaggagtgg tcctgagcac gtcagctatt ttagtggctt gtggaaaaac
     8041 tgataaagaa gcagatgcac cgacaacatt ttcttatgtc tatgcagtag atccagcatc
     8101 attgggctac agtatagcga ctcgaacatc gaggacagac gttattggaa atgttattga
     8161 tggtttgatg gaaaatgata aatacggcaa tgttgctcct tctcaaaaag actatgattt
     8221 gaacagtaca ggatgggctc caagctatca agatccagcg tcttacttga atattatgga
     8281 tccaaaatct ggttctgcca tgaaacacct tggcattacg aaaggaaaag ataaggatgt
     8341 tgtagctaaa cctggtttgg ataaatataa gaaattgtta gaagatgctg tttctgagac
     8401 cactgaccta gagaagagat atgaaaaata tgccaaagct caagcttggt cgacagatag
     8461 ttcattattg atgccaacag cttcatctgg tggttttcca gttgtaagta acgtagtacc
     8521 attctcaaaa ccatactcac aagttggtat taagggggaa ccatatatct ttaaaggaat
     8581 gaaattgcaa aaagatattg ttacaacaaa agaatataac gaggttttta aaaaatggca
     8641 aaaagaaaaa ttggaatcca atagcaaata ccaaaaagaa ctagaaaaat acattaaata
     8701 aggaatggta ttgatcttga taaaatttta aaaatactgt cattttgaat ataaaggagt
     8761 ttgatatgga gtggattaga ttaataggaa tagcaatcat tgttgtgggt tttattttaa
     8821 aatttgatac aattgcaaca gtagtcttag ctggtttggt tacagcttta gtttcaggtg
     8881 tttctctcgt tgaatttttg gagattttgg gaaaagaatt tagcaatcag cgagtgctca
     8941 cgatttttat ggttaccttg cctcttgtgg ggctgtcaga aacctttgga ctcaagcaac
     9001 gatcaatcga tttgattcga aagattaaag gtctgacagt tggaaacttc tatacagttt
     9061 atttctttat tcgagagtta gctggtttct tttcaattcg tctaggagga caccctcagt
     9121 ttgtcagacc tttggttcag cctatgggag aagcagctgc agagtctcaa ttaggtagaa
     9181 agttaacaga ggttgaagat gagacaataa aagcgcgtgc ggcagcgaat gaaaattttg
     9241 gaaatttctt tgctcaaaat acgtttgtag gtgctggggg agtcctcttg atagggggaa
     9301 cattagatca gttaggctat gaaagcaatt atgcagggat tgcttctaca tctattattg
     9361 ttgctgttat aacacttatt gtagtgggga tttacaatta tttatttgat aaaaaattga
     9421 tatcaaaaaa gactagggga ggagaacaaa aatgacagag ttggcaaagc aactattaga
     9481 gttgacctat attgtgattg gttgtcaatt tctccataca gcctattgta gttataaaga
     9541 taaaacaaac ccagttcgac ttgggacatc tgcattttgg actctattgt ctattacgtt
     9601 tataggtggt tcctatatgc caaatatgag tattggtatt attgtaatcc tattatcgct
     9661 gttaacattg tttaagcaag tccgtatcgg aaccttgcca tccttagatg aaatgaaagc
     9721 caatattgaa tctaacaggt tgaaaaataa aatttttatt ccagttatgc tgatggcaat
     9781 acttgcgttg gtcttagcgc aaatgattcc agaatttagc aagatttcga ttagccttgc
     9841 cgccttgttt gctacaattt ctgttcttgt gattaccaat agtcacccta agagtctgtt
     9901 atcagaaaat aatcgaatga ctcagcaagt ttcaacaagt gggattgttc ctcaattatt
     9961 aggggctttg ggggctattt ttactgtagc aggtgttggt gatgttatct ctcatctgat
    10021 cagcggtatt gttccttcag atagtcgctt tataggagtt ttggcctatg ttcttggaat
    10081 ggttctattc acaatgatta tgggaaatgc ttttgcagca ttcaccgtta ttacagcagg
    10141 tgttggagtt ccctttgtat ttgctctggg agctaatcca attgtggctg gtgctcttgc
    10201 catgacagca ggttattgtg ggaccttatt gaccccaatg gctgctaatt ttaacgctct
    10261 accagcagca ttgatggata tgaaagatca gaatggcgtt ataaaggctc aagcaggtgt
    10321 tgctctagta atgattgtta ttcacatatt cttaatgtac tttctcgcat tttagtaaag
    10381 gaaaataaaa tgaaaatatt ggttacaggt tttaatcctt ttggaggtga aaagattaat
    10441 ccagctttgg aggctgtaaa attattacca tctgagatta atggggctga agttcgctgg
    10501 gtagaaattc caacggtttt ttataagtcg tcagaagttt tagaggcaga aatattacga
    10561 tatcaaccag atgctgtact ttgtattgga caagcaggcg gcaggaccgg cttaacacct
    10621 gaacgagtgg ctattaatca agatgatgct cgcatacctg ataacgaagg caatcaacca
    10681 attgatacac cgattcgtat tgatggagca tcggcctatt ttagtagttt acctatcaaa
    10741 gcgatggtac aagctatcaa aaaacaggga cttccggcag ttgtatccaa tagtgcagga
    10801 acctttgttt gcaatcattt gatgtaccaa gctctttatt tagtggataa aaaattccct
    10861 aatatgagag caggtttcat gcatattcca tatatgatgg aacaagtagt aaataagccg
    10921 aatactgcag gaatgagtct atgtgatatt gtaagaggca tagaggtagc tattgaagct
    10981 attgtagact acaaagataa ggatttgcag ttagtaggcg gtgagactca ctgataacct
    11041 aaaaaggata gtcaattatg cttgtttact aactattagc tatgctaaat cgattgaggt
    11101 tgtttacata aaactctata tcagagaagc ctgatataga gttttttctt gctagtttta
    11161 ggattttctt gtaaaataga aaaagtgaag agaggtatga aatgagcaag aaagataaaa
    11221 aaatcgaaat tcaagtagcg gatgccaaag ttaatgttgg taaagacagt tttgaaggtt
    11281 atacattgac tatcggtaac aaagttatcg gagaaattgc cgaattagac ggacaatttg
    11341 ccattataaa gaatgggaat gtcgatagtt tttataaaaa attggaaaaa gctgtggaaa
    11401 ttttgattga aaattataat ttagcaaaat aagtcttgtt tttttaaaat tttcatgata
    11461 taatagtcca tgttgattgt aggagagata gcgaagaggc taaacgcggc ggactgtaaa
    11521 tccgctcctt cgggttcggg ggttcgaatc cctctctctc catttcatta atggggtata
    11581 gccaagcggt aaggcaaggg actttgactc cctcatgcgt tggttcgaat ccagctaccc
    11641 cagttcttag gtaataatca agataaaaag caaaatatct tagggtattt tatttttata
    11701 attgaaagac gtgaatgata tgaacatgtc cttgcgggtg cttaggaaaa aaattataag
    11761 tatgtcaagt ttaagaaaaa cttgattgtt ggaggatttt ttagatgaac gaatttgaag
    11821 atttgctaaa tagcgttagt caagttgaga ctggtgatgt tgttagtgct gaagtattga
    11881 cagttgatgc gactcaagct aacgttgcaa tctctggaac tggtgttgaa ggtgtcttga
    11941 ctcttcgcga attgacaaac gatcgtgatg cagatatcaa tgactttgtt aaagtaggag
    12001 aagtattgga tgttcttgta cttcgtcaag tagttggtaa agatactgat acagttacat
    12061 accttgtatc taaaaaacgc cttgaagctc gcaaagcatg ggacaaactt gttggtcgcg
    12121 aagaagaagt tgttactgtt aaaggaacgc gtgccgttaa aggtggactt tcagtagaat
    12181 ttgaaggtgt tcgtggattt atcccagctt caatgttgga tactcgtttc gtacgtaacg
    12241 ctgagcgttt tgtaggtcaa gaatttgata ctaaaatcaa agaagttaac gctaaagaaa
    12301 accgcttcat cctttcacgt cgtgaagttg ttgaagcagc tactgcagca gctcgcgctg
    12361 aagtattcgg taaattggct gttggtgatg ttgtaactgg taaagttgct cgtatcacaa
    12421 gcttcggcgc tttcatcgac cttggtggtg ttgacggatt ggttcacttg actgaattgt
    12481 cacatgaacg taacgtatca ccaaaatcag ttgtaactgt tggtgaagaa attgaagtga
    12541 aaatccttga tcttaacgaa gaagaaggac gtgtatcact ttcacttaaa gcaacagtac
    12601 caggaccatg ggatggcgtt gagcaaaaat tggctaaagg tgatgtagta gaaggaacag
    12661 ttaaacgttt gactgacttc ggtgcatttg ttgaagtatt gccaggtatc gatggacttg
    12721 ttcacgtatc acaaatttca cacaaacgga ttgaaaatcc aaaagaagct cttaaagttg
    12781 gtcaagaagt tcaagttaaa gttcttgaag ttaacgcaga tgcagaacgc gtgtcacttt
    12841 ctattaaagc tcttgaagaa cgtccagccc aagaagaagg acaaaaagaa gaaaaacgtg
    12901 ctgctcgtcc acgtcgtcca agacgtcaag aaaagcgtga tttcgaactt ccagaaacac
    12961 aaacaggatt ttcaatggct gatttgtttg gtgatatcga actttaatca aattgaaaat
    13021 tcacaaaatc ctttgtttac taaacaaggg atttttctgg ctctttgtca actgtagtgg
    13081 gttgaagtca gctaagcttg agaaaggaca aatttcgtcc tttctttttt gatgttcaaa
    13141 gcgataaaaa tccgtttttt gaagttttca aagtttcgaa aaccaaaggc attgcgcttg
    13201 ataagtttga tgagattatt ggtcgcttcc agtttggcat tagaatagtg tagttgaagg
    13261 gcgttgataa tcttttcttt atctttgagg aaggttttaa agacagtctg aaaaatagga
    13321 tgaacctgct taagattgtc ctcaataagc ccgaaaaatt tctctggttc cttattctgg
    13381 aagtgaaaaa gcaagagctg atagagctga tagtggtgtt tcaagtcttc cgaataactc
    13441 aaaagcttgt ttaaaatctc tttattggtt aagtgcatat gaaaagtagg acgataaaat
    13501 cgcttatcac tcagtttacg gctatcctgt tgaatgagtt tccagtagcg cttgatagcc
    13561 ttgtattcat ggtattttcg atgaaactga ttcatgattt gaacacgcac acgactcata
    13621 gcacggctaa gatgttgtac aatgtgaaag cgaagctgtt tagccaagtc atagtaaggg
    13681 ctaaacatat ccatagtaat aattttgacg cgacatcgga cggctctatc atacttaaga
    13741 aagtgatctc ggatgacagc ttgtgttctt ccctcaagaa cagtgatgat atcgagcttt
    13801 tcaaaatctt gcgcaataaa gctcatctcc atctcccgat tgaaacagtc actccccgga
    13861 ctgtttcaac gttccaggac ataatctcag gaagacaaga aaaatcatgt ttaaagtgaa
    13921 aatcattgag ctttcgaatg acagttgaag ttgaaatggc cagctgatga gcaatatcgg
    13981 tcatagaaat cttttcaatt aacttttgcg caattttttg attgataata cgagggattt
    14041 ggtgattctt cttgacgata gaagtttcag cgaccatcat tcttgaacag tgatagcact
    14101 tgaatcgacg ctttctaagg agaattctag taggcatacc agttgtctca aggtaaggaa
    14161 tcttagacgg tttttgaaag tcatatttct tcaattggtt tccgcactca gggcaagatg
    14221 gggcgtcgta gtccagtttg gcgatgattt ctttgtgggt atccatattg atgatatcta
    14281 gaatcttgat gtttgggtct ttaatatcga gtagttttgt gataaaatgt aattgttcca
    14341 tatgaatctt tctaatgagt tgttttgtcg cttttcatta taggtcatat gggacttttt
    14401 ttctacaaca aaataggctc cataatatct ataggggatt tacccactac aaatattata
    14461 gagcccaaaa tcctttgttt actaaacaag ggatttttct tttgtctctg ctcctttttt
    14521 gatataatag ttctatgtta aaatcagaaa aacaatcacg ttatcaaatg ttaaatgaag
    14581 aattgtcctt cctattggaa ggcgaaacca atgttttggc taatctttcc aacgccagtg
    14641 ctctcataaa atcacgtttt cctaataccg tatttgcagg cttttatttg ttcgatggaa
    14701 aggaattggt tttaggtccc ttccaaggag gtgtttcctg catccgtatt gcactaggca
    14761 agggtgtttg tggtgaggca gctcactttc aggaaactgt tattgttgga gatgtgacga
    14821 cctatctcaa ctatatttct tgtgatagtc tagctaaaag tgaaattgtg gtgccgatga
    14881 tgaagaatgg tcagttactt ggagttctgg atctggattc ttcagagatt gaggattacg
    14941 atgctatgga tcgagattat ttggaacaat ttgtcgctat tttgcttgaa aagacagcat
    15001 gggactttac gatgtttgag gaaaaatctt aatgtatcaa gcactttatc gaaaatatag
    15061 aagtcaaaac ttctcccagt tagttggtca agaagttgtg gctaagactc ttaaacaagc
    15121 ggtggagcaa gagaaaataa gtcacgctta tcttttttct ggtcctcgtg gaacgggaaa
    15181 aaccagtgtt gctaaaatct ttgccaaggc tatgaactgt cccaatcaag tgggtggcga
    15241 accttgcaat aactgctata tttgtcaagc agtgacggac ggtagtttag aagatgtcat
    15301 tgaaatggat gcagcttcta ataatggggt agatgaaatt cgcgaaattc gtgataaatc
    15361 tacctatgcg cctagccttg ctcgttataa ggtttatatc atagatgagg ttcacatgct
    15421 gtctacagga gcttttaatg ccctcctaaa gacgctggaa gaaccaacac agaatgtagt
    15481 ctttattttg gccactactg aattgcacaa gattcctgct actattctat cccgtgtgca
    15541 acgttttgag tttaaatcaa ttaagacaca ggatattaag gaacatattc actatatctt
    15601 agaaaaagaa aatatcagtt ctgaaccaga ggctgtggaa atcattgcca gacgggcgga
    15661 aggtggaatg cgggacgcct tgtctatttt ggatcaagcc ctgagtttga cacagggaaa
    15721 tgagctgacg actgctatct ctgaagaaat tactggcacc attagcctat cagccttgga
    15781 tgattatgtg gcggccttgt ctcaacagga tgttcccaaa gctttgtctt gcttgaatct
    15841 tctttttgac aatggtaaga gcatgactcg ttttgtgacc aatcttttgc actatttaag
    15901 agacttgtta attgttcaaa cagggggaga aaatactcat catagttcag tctttgtaga
    15961 aaatttggca cttcctcaaa aaaatctgtt tgaaatgatt cgcttagcaa cagtgagttt
    16021 agcagatatt aagtctagtt tgcagcccaa gatttatgct gaaatgatga ccgtccgttt
    16081 ggcggaaatc aagtccgaac cagctctatc aggagcggtt gaaaatgaaa ttgctacgct
    16141 gagacaggaa gttgcccgtc tcaaacaaga gctttctaat gtaggtgcgg ttcctaaaca
    16201 agttgcacca gctcctagtc gaccagctac gggcaaaaca gtctatcgtg tcgatcgcaa
    16261 taaagtgcaa tctatcttac aagaggccgt cgaaaatcct gatttagcac gtcaaaatct
    16321 aattcgtttg cagaatgcct ggggagaggt aattgaaagt ctaggtgggc cggacaaggc
    16381 tctgctagtt ggttctcaac cggttgctgc caatgaacac catgctattc ttgcttttga
    16441 gtctaacttc aatgctggtc aaactatgaa acgagacaat ctcaatacca tgtttggtaa
    16501 tatcctcagt caggcggcag gtttttcacc tgagatttta gctatttcca tggaggaatg
    16561 gaaagaagtt cgcgcagcct tttcagccaa agccaaatct tctcaaactg aaaaggaagt
    16621 agaagaaagc ctgattccag aaggatttga atttttggct gataaagtga aggtagagga
    16681 agactaaaga aagatttcat gatacaataa gtttatgaat aaacaacaat ttattattat
    16741 ggcgctgttt acagctgctg agacctattt tttcaatgaa gcctggatga ctggccgcta
    16801 tattatggca gccttttggg caattttact ctttagaaat ttccgagtca gttatgtgat
    16861 gggcaaaatc gttgatgtca tcgatcagca ttttaatagg aaagactagc cctcagcttc
    16921 cagacaaaat caaagccttt taggcttttt tttgttatac tagaaaagta tatttataga
    16981 atttttgctc tatttctggg gaaatcagac gtttttctag taagtactgt aaaagttttg
    17041 aaaaagaaag gaactatcat gtcagtatta gagatcaaag atcttcacgt tgagattgaa
    17101 ggaaaagaaa ttttaaaagg ggttaacctg accctgaaaa caggagaaat tgccgctatc
    17161 atgggaccaa atggtacagg taaatcgact ctttctgccg ctatcatggg aaatccaaac
    17221 tatgaagtaa ctaaaggtga agttttgttt gatggcgtaa acatccttga gttggaagtg
    17281 gatgagcgtg cgcgtatggg acttttcctt gctatgcaat acccatcaga aatccctgga
    17341 attaccaatg ctgagtttct tcgtgccgct atgaatgcgg gtaaagaaga tgatgagaag
    17401 atttcagttc gtgagtttat tactaagcta gatgaaaaaa tggaattgct caacatgaaa
    17461 gaagaaatgg cagagcgtta cctcaacgaa ggcttctctg gtggtgagaa aaaacgcaat
    17521 gaaattcttc aacttttgat gttggagcca acatttgctc ttttggatga gattgactca
    17581 ggtcttgata ttgacgctct taaagttgtg tctaaaggtg tcaatgccat gcgtggtgaa
    17641 ggttttggtg ctatgatcat tactcactac caacgtcttt tgaactatat cacacctgat
    17701 gtggtacacg tgatgatgga aggtcgtgtt gtcctttctg gtggtccaga attggctgcg
    17761 cgtttggaac gtgaaggata cgcaaaatta gctgaagaac ttggctacga ctacaaggaa
    17821 gaattgtaat ttcctcgtat cttttaggag aagtaaatga ctagagaaaa tattaaactt
    17881 ttttcagaaa tgcacgctga accaagctgg ttggctgatc tccgtcaaaa agcttttgac
    17941 aagattgaga ctttggaatt accagttatt gagcgtgtca aattccaccg ttggaatctg
    18001 ggtgatggaa cgattacaga aaatgagcca tcagcaaatg ttccagattt cacagcttta
    18061 gatcatcact tgaagttggt gcaagtagga actcaaactg ttttcgaaca aactccagtt
    18121 gagttagctg aacagggtgt tgtcttcaca gactttcact cagctttaga agaaattcca
    18181 gagctgatcg aagaattctt catgtcatct gttaagtatg atgatgacaa gttggcggct
    18241 taccacacag cttactttaa cagtggtgct gtactctata ttccagataa cgtagaaatc
    18301 acagagccaa ttgaaggaat tttctaccaa gatagcgata gcaatgtgcc gtttaacaag
    18361 catattatga ttatcgctgg taaaaattct aagattagtt atctggagcg tttagagtca
    18421 cgcggtgaag gaagtgacaa agtaactgcc aatatcacag tggaagtgat tgcacgttct
    18481 ggtgcgcaag tcaagtttgc tgctatcgac cgtctaggtg aaaacgtcac tgcctacatt
    18541 agccgtcgtg gtaaattagg caacgatgca agtattgact gggctatcgg tgtcatgaac
    18601 gaaggaaatg tcgttgctga ttttgatagt gacttgattg gtaatggtag ccatgctgac
    18661 ctcaaggttg tagctctttc aagtggtcgt caggtacaag ggattgatac tcgtgtaact
    18721 aactatggct gcaactcaat cggaaacatt ctacaacatg gggttatcct tgaaaaagca
    18781 actttgactt tcaatggtat cggccacatc atcaagggtg ctaagggagc agatgcgcaa
    18841 caagagagcc gtgttctcat gctttcagac caagcgcgtt cagatgctaa cccaattctt
    18901 ttgattgatg aaaatgacgt aactgcaggc catgcagcct ctattggtca ggtagatcca
    18961 gaagatatgt actacctcat gagtcgtggc ttggataagg caactgcaga gcgtttggtt
    19021 gttcgtggtt tccttggatc tgttatcgtg gagattccag tcaaggaagt tcgtgatgaa
    19081 atgattgcaa ctatcgaaga gaaattgtca aaacgctaag gggcagccta tgttagatgt
    19141 agaagcgatt cgcaaggatt ttccaatttt agatcagatt gtcaatgatg aacctctggt
    19201 ctatctggac aatgctgcga cgacacaaaa accactagta gttctgaaag ctattaacag
    19261 ctactatgag caggacaatg ccaatgttca ccgtggtgtc cataccttag cggaacgagc
    19321 gacagcttct tatgaagctg ctcgtgaaac cattcgtaag tttattaatg caggctctac
    19381 aaaggaagtt ctctttacca gaggaacgac aaccagcctt aactgggtgg cacgctttgc
    19441 tgaggaaatt ctcactgagg gagaccaggt cttgatttca gtaatggaac accattctaa
    19501 tatcattcca tggcaggaag cttgtcgaaa gactggagca gagcttgtct atgtctatct
    19561 taaagacggt gccttggata tggaggattt gcgagctaaa ttgactgata aggttaaatt
    19621 tgtttcccta gctcatgcct ccaatgttct tggtgtggtc aatccgatca aggaaatcac
    19681 tcaattagcc caccaagttg gggcaatcat ggtagtggat ggtgctcaat ctacacctca
    19741 tatgaagatt gatgtccagg acttggatct ggactttttc gccttttcgg gtcacaagat
    19801 ggctggtccg actggtatcg gtgtccttta cggcaaagaa aagtatcttg agcaaatgtc
    19861 tccagtagaa tttggcggcg agatgattga ttttgtctac gagcaatctg ctagttggaa
    19921 ggaattgcct tggaaatttg aggctggaac gccaaatatg gcaggagcta ttggacttgc
    19981 gactgcagtt gattatctgg aaaagattgg tatggatgcc attgaagctc atgaacagga
    20041 attgattgcg tacgtctatc caaaactgca ggcaattgag ggattgacca tttacggttc
    20101 tcaggatttg gctcaacgtt cgggtgttat tgcctttaac ctaggtgatc tccatcctca
    20161 cgatcttgcg acggctctgg attatgaagg agtggctgtt cgtgctggtc accattgtgc
    20221 gcaacccttg cttcagtatt tggaagtccc agcaacagct cgtgcaagtt tttatatcta
    20281 caataccaag gcagattgcg acaaactagt cgatgcccta caaaagacaa aggagttttt
    20341 caatggcact ttctaaacta gatagccttt atatggcagt ggtagcagac cattcgaaaa
    20401 atccacatca ccaagggaag ttagaagacg ctgagcaaat cagtctcaac aatccgactt
    20461 gtggggatgt catcaacctc tctgtcaagt ttgatgcaga ggaccgtttg gaagatattg
    20521 cttttctaaa ttcaggatgc acgatttcaa ctgcttctgc tagtatgatg acagatgccg
    20581 ttttaggaaa aaccaaacaa gaaattttag aactggcgac tattttttct gaaatggttc
    20641 aagggcaaaa agatgagcgt caagaccaac ttggagacgc ggcattcttg tcaggtgttg
    20701 ccaaattccc tcaaagaatc aagtgtgcaa ccctagcttg gaatgccctt aagaaaacaa
    20761 ttgaaaatca agaaaaacag taagacaagt ttcttttgtc ttatgaatta ttagaaatga
    20821 agaaagaaag gatactatgg ctgaagaaag agtagaacca aaaccaattg accttggtga
    20881 atataaattt ggtttccatg acgatgtaga gcctgtctta tcgacaggaa aaggactcaa
    20941 cgaaggtgtt attcgtgaat tatctgctgc taagggtgag cctgagtgga tgttggagtt
    21001 ccgtttgaag tcttatgaaa ccttcaaaaa aatgcccatg caaacttggg gagcagactt
    21061 gtcagagatt gactttgatg acttaatcta ctaccaaaaa ccatctgaca aaccagcccg
    21121 ttcttgggat gatgtacctg aaaagattaa agaaaccttt gaacgtatcg ggattccaga
    21181 agctgaacgt gcttatttag caggggcttc tgcccagtac gagtcagaag tggtttacca
    21241 caacatgaag gaagagttcc aaaaattagg tattatcttt acagatacag attccgcact
    21301 caaggaatac ccagacttat ttaaacaata ctttgcgaag ttggtaccgc cgacagataa
    21361 caagttggca gccctcaact cagcagtatg gtcgggtgga acttttatct acgtgccaaa
    21421 aggtgtcaag gtagatattc cacttcaaac ttatttccgt atcaataacg aaaatatagg
    21481 tcagttcgaa cgtaccttga ttatcgttga tgagggagca agcgtccact acgtagaagg
    21541 atgtacagca ccaacatatt caagcaatag cttgcacgct gccattgtag aaatttttgc
    21601 tttggacgga gcttatatgc gttatacaac tatccaaaac tggtctgata acgtctataa
    21661 cttggtaaca aagcgtgcta aggctcaaaa ggatgccact gttgagtgga ttgatggaaa
    21721 cttgggtgcc aaaacgacta tgaaatatcc atctgtttac cttgatggag aaggagcgcg
    21781 tggtaccatg ctctctatcg cctttgctaa tgcagggcaa caccaagaca cgggtgctaa
    21841 gatgattcac aatgctccac ataccagctc gtctattgtg tctaaatcca tcgctaaagg
    21901 tggaggaaag gttgactacc gtggacaagt cacctttaac aagaactcta agaaatctgt
    21961 ttcccacatt gaatgtgata ccattatcat ggatgacttg tcagcatcag atactattcc
    22021 atttaatgaa attcacaact cgcaagtggt tttggaacac gaagccaaag tatctaagat
    22081 ttcagaagag caattgtatt atctcatgag ccgtggattg tcagaatctg aggcaactga
    22141 aatgattgtc atgggatttg tagaaccctt tacaaaagaa cttccaatgg aatacgcagt
    22201 tgagctgaac cgcttgatta gctatgaaat ggagggatca gttggataaa atttgatttt
    22261 atactcttcg aaaatctctt caaaccacgt cagcatcgcc ttaccgtatg tatggttact
    22321 gacttcgtca gtttcatcta caacctcaaa acagtgtttt gagcaacctg aggctagctt
    22381 cctagtttgt tctttgattt tgagtattag atttactcaa aatcaaggat tttgaagatg
    22441 aacttgtatc aaaaaatcgc ggtttaaaat cgcgattttt tataatttct cgttaacaaa
    22501 gcggacaaac tgattccacc aaacttttaa gaagaaggct ttttcaattt tcttgtctgc
    22561 taccatttcg aaactagggc gctctgtggt gatgtaacct tgaccaatca agtccttgtc
    22621 ttcataagtc aaatggccaa ccactgttcc agcttcaagt ggtgctggga ttgctttgga
    22681 atcaggtgtg aattgaacag attgggaaga ttgattccca acacgttcga ttagatagat
    22741 atcctctgga gccactgcag ttactgtatc ttcttttcca tcttgtacag gggctttgct
    22801 atcttgatag gcatcgcctt gttgaacgat tttgcgaagt gtaaatgtag aagaaatata
    22861 atccattagg gaagatgtag ctgtaaatcg agcgtaagga ttattgtctt gatgatctgc
    22921 atttaaaaca actgtgatga ctctcatgcc tttttcgaca gtagtaccaa caaaagactc
    22981 tccagcctta tctgttgttc ctgtttttag cccatcaaaa ccaccacggt aagcaggcat
    23041 accttctaac atgtagttgg ttgaagtgat tgtcattcca gcaaaagtag aagaaggttt
    23101 ttttgtgatt tccaagactt gtgggtattt tttgatgagg ttgcgagcaa cgatagcgac
    23161 atcataagca ctaagcttat tttcctcatc ttttttagaa cctgggtaaa tgttatcccc
    23221 tagagtttca ttgttaagac ctgtcgtatt gacaacagtg gcatcctgaa ttccccattc
    23281 caagagtttt gcccgcatca tatcgacgaa atctttttct gagccagcaa ttttctcagc
    23341 tagggcaata gcggcgctgt tggcactaga taccagagtt gcttcaagca actcttcgac
    23401 agtataatta cgggcctcca taggaatatt actggcttca gaatttgtcg tcaattgata
    23461 aggataatca gaaatatcta caggagtgga gagggtaata cttccgtttt ccaaagcttc
    23521 atagaccaga taaacagtaa tcaattttgt tatggaagca atttcgacag gttgcgttgc
    23581 atccttctca tagagaattt taccagtatt tgcctcaaca gcaatcgcat gtttagcggc
    23641 aatggtaaaa tcttgagcaa cagcagtaga agccccccct aaaagagaga cagttaacaa
    23701 agttaaaaat atttttttca tagtagtttt attctatcat aaagaaaaaa aatattcttg
    23761 ctttaataat tcatctgtta agctttttga aaatatggta aaataaagtg agggaggtaa
    23821 ctcatgtttc gtagaaataa attatttttt tggaccacag aaattttact cttaaccatc
    23881 atcttttacc tatggagaca gatggggtct ttgattaacc cttttgttag cgtgcttaat
    23941 acaattatga ttccattttt attagggggc tttctttatt atttgacaaa ccctattgtt
    24001 actttcttaa ataaagtctg taaactcaat cgtttgcttg gtattttaat taccttgtgt
    24061 actttggtct ggggaatggt cataggtgtt gtctatctct tacctatttt gattaatcag
    24121 ttatctagtt tgattatatc tagtcaaact atttatagtc gagtacaaga cttaatcata
    24181 gacttatcta attatcctgc gctccagaat ttggatgtag aagctacaat tcagcagtta
    24241 aacttatcct atgttgatat tcttcaaaat atcctaaata gcgtatcaaa tagtgtgggg
    24301 agcgtcttgt cagctcttat cagtactgtt ttgattttga ttatgactcc agtttttttg
    24361 gtttatttct tattagatgg acataaattc ttgcccatgc ttgaaagaac gattctaaag
    24421 agggatcgct tgcatattgc aggcttatta aagaatttaa atgcgacgat tgctcgctat
    24481 attagtggag tttcgattga cgcaatcatt ataggttgtt tggcttatat tggctatagt
    24541 attattggtt taaaatatgc tttagttttt gccatttttt ctggtgtagc caatttaatt
    24601 ccttatgtgg ggccaagtat tggtttgatt cctatgatca tcgcaaatat attcactgat
    24661 ccccatagac tgctgattgc agtgatttat atgcttgttg ttcagcaggt agatggcaat
    24721 atcttatatc ctcgaatcgt aggaagtgtt atgaaggttc atccaatcac gattttagtt
    24781 ttacttttgt tgtcaagcaa tatctatggt gtagttggaa tgattgtcgc agtgccaacc
    24841 tattctatct tgaaagaaat ttctaagttc ttatcccgtt tgtatgaaaa tcataaaata
    24901 atgaaagaac gagaaagaga attagctaag taaaagtcag gagaaccctg atttttcttt
    24961 actggaagtg gcctttagat tagaagactg aaaataagtt aaagtcttaa actaattttc
    25021 acagctaaga atagtagaag ttaatctgat aaaaatcgaa aaaaccagtg gaattccgtg
    25081 tcagggtaag ttccactggt tttcatagtc tattaaagtt cgaatgaaac ctatttataa
    25141 tatattgaaa ctagaatagt acacctctaa ttctaaaaca ttgttagaaa tcgatttgac
    25201 tgtcctgatc tattcgtcct attcttattt cattttacta tattttggtg caataagtga
    25261 aaagtagtcc gaataatata aggattgatt ttatagtttt taaactcaaa tgaattaaaa
    25321 taaagagagt acgaaaattc tcatctgaaa gtattttaga ataattctct tcgtgaattt
    25381 cttcaaaaca gatagcttca tcttaggtat gtgttaattg gatttcgtaa gctctattta
    25441 caatcgtaaa gttatgcact gaaaaagttg tagttagtct tccagtttgc taaatttctc
    25501 gaatagtatc ttttttaggt atgtgatttc tttttgcatt tttgagttag ataaggtata
    25561 atggttttat tgtcttttgg ggtcgttacg gattcgacag gcattatgag gcatattttg
    25621 cgactcgtgt ggcgacgtaa acgctcagtt aaatataact gcaaaaaata acacttctta
    25681 cgctctagct gcctaaaaac cagcaggcgt gacccgattt ggattgctcg tgttcaatga
    25741 caggtcttat tattagcgag atacgattaa gccttgtcta gcggcttgat aagagattga
    25801 tagactcgca gtttctagac ttgagttatg tgtcgagggg ctgttaaaat aatacataac
    25861 ctatggttgt agacaaatat gttggcaggt gtttggacgt gggttcgact cccaccggct
    25921 ccattattcc tttgcattct tttgcattcc ttggtaaaac gttgttaaat caacgttttt
    25981 tatttttatc tttggtattc ctttgcattc ttttgctaaa aagggagtca caaacagacc
    26041 ctattttaaa aaaaggatag aaaaaaggat acaacatttg tcgcatccta aaaataatct
    26101 tttttccacg gaagacatgg gattcgaacc cacgcacgct attacacgcc taccgcgttt
    26161 ccaacacggc ctcttaagcc tcttgagtaa tcttccaata cttactcaaa tagtctacca
    26221 taaaggctct tatcttgcaa taaaaattct agaaataaga aaaatgatag attttgaaag
    26281 aaaatgataa aaaatgcttg acttcgaaat aaagtatggt agaatgaata gtgtaaacga
    26341 taacaggagg tgattcagtg ttaaaaacag aacgtaaaca actgatttta gaggagttaa
    26401 atcaacatca tgtagtttct ctagaaaaat tagttagttt gctagaaacg tcagaatcaa
    26461 cggttcgaag agacttggat gagttggaag cggaaaacaa gcttcgtcgt gtgcatggtg
    26521 gagcagaact cccccactcc ttacaggaag aagaaaccat tcaagaaaaa tctatcaaaa
    26581 accttcaaga aaagaaattg ctggctcaga aagcagcctc tctcattaaa gaaaaagatg
    26641 tcatctttat cgatgctgga acaacaactg cttttttgat tcatgaattg gtcaataaga
    26701 atgttacagt tgtgaccaac tccattcacc atgccgctca gttggttgaa aagcagattc
    26761 caactgtcat ggttggagga aacgtcaaga cggcgacaga tgctagtatc gggggcgttg
    26821 ctcttaacca gattaaccaa ttgcactttg accgtgcctt tatcggaatg aatggtgttg
    26881 acgatggcta ttatacgact cctgatatgg aggagggagc tgtgaaaaga gctattttgg
    26941 agaatgccaa gcagacctac gtcttggtgg attcgtcaaa aattggacaa acttgctttg
    27001 ccaaggtagc cccactcaaa cgcgctatcg ttatcactag tcaagggcat gagctcttgc
    27061 aggttattaa ggagaaaacg gaggtaatag aagtatgatt tatacagtca cactcaatcc
    27121 atccattgac tatatcgttc gtttggacca agtcaaagtt ggtagtgtaa atcgtatgga
    27181 cagtgatgat aagtttgctg gtgggaaagg aatcaatgtc agccgtgtct tgaaacgttt
    27241 gaatatacca aatacagcga cgggatttat cggtggcttt actggtaaat ttatcacaga
    27301 tactttagca gaggaagaaa tcgagacacg ttttgtccag gtggcagaag atactcgtat
    27361 taatattaaa atcaaagcag accaagaaac agaaatcaac ggaacgggtc caactgttga
    27421 accggttcag ctagaagaat tgaaagctat tttatctagt ctgacagcag aagatacagt
    27481 tgtctttgca ggttcaagtg ctaaaaatct aggcaatgtt atctataagg atttgatttc
    27541 cttgacgcgc cagactggtg cgcaagtggt ctgtgacttt gaaggacaga ccttaattga
    27601 tagtttggac taccagcctc ttcttgtaaa accaaacaat catgaacttg gagcgatttt
    27661 tggggttaaa ctcgaaagtt tagatgaaat tgagaaatac gctcgtgagt tactggctaa
    27721 gggtgctcaa aatgttatta tctctatggc tggtgatggc gcccttcttg tcacatctga
    27781 gggagcttac ttcgctaaac caatcaaagg aacagtcaaa aattcagttg gagctggtga
    27841 ttctatggtt gctggattca caggtgaatt tgtcaaatca aaagacgcag tagaagcctt
    27901 caaatgggga gtggcttgcg gaacggcaac taccttctca gatgacttgg caacggcgga
    27961 atttattaaa gaaacatatg gaaaagttga ggtagaaaaa cgatgaaaat tcaagattta
    28021 ttgagaaaag atgtcatgtt gctggatttg caggcaactg aaaaaacagc tgtcatcgac
    28081 gagatgatta aaaatttgac agagcacggt tatgtaacag attttgaaac atttaaagaa
    28141 ggaattttgg cgcgtgaagc tttgacttct actggtttgg gtgatggaat cgcaatgcct
    28201 cacagcaaaa acgctgctgt caaagaagcg acagttctat ttgctaagtc aaataagggt
    28261 gttgactacg agagcttgga tggacaagca actgacctct tcttcatgat tgcagctcca
    28321 gaaggtgcca atgatactca cttggcagcc ttggcagaat tgtctcaata cttgatgaaa
    28381 gacggttttg cagacaaact tcgtcaagca acatctgcag accaagttat cgaacttttt
    28441 gaccaagctt cagaaaaaac tgaggaactt gttcaagcac ctgctaatga ctctggtgac
    28501 tttatcgtag ctgttacagc ttgtacaaca ggtattgccc acacttacat ggcccaagaa
    28561 gcccttcaaa aagtagctgc tgaaatgggg gttggtatca aggtcgaaac caacggtgct
    28621 agcggtgttg gaaatcaact aactgcagaa gatatccgta aggctaaagc tattatcatt
    28681 gcagcagaca aggccgttga aatggatcga tttgatggaa aaccattgat caatcgtcca
    28741 gttgctgacg gtatccgtaa gacagaagag ctaattaact tggctctttc aggagatact
    28801 gaagtctacc gtgccgctaa tggtgcaaaa gctgcaacag cctctaacga aaaacaaagc
    28861 cttggtggtg ccttctacaa acacttgatg agtggtgtat ctcaaatgtt accattcgtt
    28921 atcggtggtg gtatcatgat tgcccttgcc ttcttgattg acggtgcttt gagtgttcca
    28981 aatgaaaacc ttggcaatct tggttcttac catgagttag cttctatgtt catgaaaatt
    29041 ggtggagctg cctttggttt gatgcttcca gtctttgcgg gttatgttgc ctactctatt
    29101 gctgaaaaac caggtttggt agcaggtttc gtggctggtg ctattgccaa agaaggtttt
    29161 gcctttggta aaattcctta tgccgcaggt ggtgaagcaa cttcaactct tgcaggtgtc
    29221 tcatctggtt tcctaggtgc ccttgttggt ggatttatcg caggtgcctt ggttcttgcc
    29281 atcaagaaat acgttaaagt tcctcgttca ctcgaaggtg ctaaatcaat ccttctattg
    29341 ccacttcttg gaacaatctt gacaggattt gttatgctag ctgtaaatat cccaatggct
    29401 gcaatcaaca ctgctatgaa tgacttccta ggcggtcttg gaggaggttc agctgtcctt
    29461 cttggtatcg tccttggtgg aatgatggct gttgacatgg gtggaccagt taataaagca
    29521 gcttatgttt ttggtacagg tacgcttgca gcaactgttt cttcaggtgg ttctgtagcc
    29581 atggcagcag ttatggctgg aggaatggtg ccaccacttg caatctttgt cgcaactctt
    29641 cttttcaaag ataaatttac taaggaagaa cgtaactctg gtttgacaaa catcatcatg
    29701 ggcttgtcat ttatcactga gggagcgatt ccatttggtg ccgctgaccc agctcgtgcg
    29761 attccaagct tcatccttgg ttcagcagta gcaggtggac tcgttggtct tactggtatc
    29821 aaactcatgg cgccacacgg aggaatcttc gttatcgccc ttacttcaaa tgctctcctt
    29881 tacctcgttt ctgtcttggt aggagcaatc gtaagtggtg tggtttatgg ttacctacgc
    29941 aaaccacaag cataaaaaat agaaaaatga aaagattgga ccgtttggtg cagtcttttt
    30001 ctcttcccga aatgcctgtg aaatatggta taatagaaga atggcaaaca agaatacaag
    30061 tacaacaaga cggagaccgt ctaaagcaga actggaaaga aaagaagcga ttcaacgaat
    30121 gttgatttcg ttaggaattg cgattttatt gattttcgca gccttcaaat taggggctgc
    30181 aggtataacc ctttataatt taattcgctt gctagtgggt agcctagctt atctggcgat
    30241 attcggccta ttaatctatc tcttcttttt caagtggata cgaaaacagg aaggactctt
    30301 atctggcttt ttcaccatat ttgctggctt actcttgatt tttgaggcct acttggtttg
    30361 gaaatatggt ttggacaagt ccgttctaaa agggaccatg gctcaggttg tgacagatct
    30421 gactggtttt cgaacgacta gttttgctgg agggggcttg atcggggtcg ctctttatat
    30481 tccaacagcc tttctctttt caaatatcgg aacttacttt attggttcta tcttgatttt
    30541 agtgggttct ctcctagtca gcccttggtc tgtttacgat attgctgaat ttttcagtag
    30601 aggctttgcc aaatggtggg aagggcacga gcgtcgaaaa gaggaacgct ttgtcaaaca
    30661 agaagaaaaa gctcgccaaa aggctgagaa agaggctaga ttagaacaag aagagactga
    30721 aaaagcctta ctcgatttgc ctcctgttga tatggaaacg ggtgaaattc tgacagagga
    30781 agctgttcaa aatcttccac ctattccaga agaaaagtgg gtggaaccag aaatcatcct
    30841 gcctcaagct gaacttaaat tccctgaaca ggaagatgac tcagatgacc aagatgttca
    30901 ggtcgatttt tcagccaaag aagcccttga atacaaactt ccaagcttac aactctttgc
    30961 accagataaa ccaaaagatc agtctaaaga gaagaaaatt gtcagagaaa atatcaaaat
    31021 cttagaagca acctttgcta gctttggtat taaggtaaca gttgaacggg ccgaaattgg
    31081 gccatcagtg accaagtatg aagtcaagcc ggctgttggt gtaagggtca accgcatttc
    31141 caatctatca gatgacctcg ctctagcctt ggctgctaag gatgtccgga ttgaagcacc
    31201 aatccctggg aaatccctaa tcggaattga agtgcccaac tccgatattg ccactgtatc
    31261 tttccgagaa ctatgggaac aatcgcaaac gaaagcagaa aatttcttgg aaattccttt
    31321 agggaaggct gttaatggaa ccgcaagagc ttttgacctt tctaaaatgc cccacttgct
    31381 agttgcaggt tcaacgggtt cagggaagtc agtagcagtt aacggcatta ttgctagcat
    31441 tctcatgaag gcgagaccag atcaagttaa atttatgatg gtcgatccca agatggttga
    31501 gttatctgtt tacaatgata ttccccacct cttgattcca gtcgtgacca atccacgcaa
    31561 agccagcaag gctctgcaaa aggttgtgga tgaaatggaa aaccgttatg aactctttgc
    31621 caaggtggga gttcggaata ttgcaggttt taatgccaag gtagaagagt tcaattccca
    31681 gtctgagtac aagcaaattc cgctaccatt cattgtcgtg attgtggatg agttggctga
    31741 cctcatgatg gtggccagca aggaagtgga agatgctatc atccgtcttg ggcagaaggc
    31801 gcgtgctgca ggtatccaca tgattcttgc aactcagcgc ccatctgttg atgtcatctc
    31861 tggtttgatt aaggccaatg ttccatctcg tgtagcattt gcggtttcat caggaacaga
    31921 ctcccgtacg attttggatg aaaatggagc agaaaaactt cttggtcgag gagacatgct
    31981 ctttaaaccg attgatgaaa atcatccagt tcgtctccaa ggctccttta tctcggatga
    32041 cgatgttgag cgcattgtga acttcatcaa gactcaggca gatgcagact acgatgagag
    32101 ttttgatcca ggtgaggttt ctgaaaatga aggagaattt tcggatggag atgctggtgg
    32161 tgatccgctt tttgaagaag ctaagtcttt ggttatcgaa acacagaaag ccagtgcatc
    32221 catgattcag cgtcgtttgt cagttggatt taaccgtgcg acccgtctca tggaagagct
    32281 tgagatggca ggtgtcattg gtccagctga aggtaccaag ccaagaaaag tattgcagca
    32341 ataaaaaata gcttctttcc aaggttggaa ggagctattt tactggttat tgattacttt
    32401 tatactcttc gcaaatctct tcaaaccacg tcagcttcgc cttgtcgtag gtatatgata
    32461 ctgactctgt cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgcggctagc
    32521 ttcctagttt gctctttgat tttcattgag tattattttc tgaagttgga gtattgggct
    32581 gtttttcgtt ttcagtagca ggtttacttg aagcaggagt agaagagtcc tgagttgctg
    32641 ttttctgatc ttcttttttc tcttccttga cgctagattt tggtgtttcc tcttgctgtg
    32701 ttttttcttg actagtgtta gtctctttag ttggactggt gttttcctta ggggattcct
    32761 tttggatttc tttgacaatg gttgtcgtct ggcttgtcgt aggttctttt ttaatatttt
    32821 tgttattatc caaggcgttc ataatcgtga tacttgcggt aatcaagcca aggatactag
    32881 cgattgtagc aacggttttt tgaaagactg taaagccttt tttgatgtgt tctgtttttg
    32941 gttttgaagt tctacgatag ttagacatac attctctcct ttgattatga tttattatac
    33001 tctgtttctt taaaaaaatc ttaaaaaaag agaaatttcc ctttcttgtc gcaagctccg
    33061 tttcatgata caatagagga agtgatttta gaaagcgtga gaaacatgat ttactttgat
    33121 aattcagcga cgaccaagcc ttatcctgaa gcccttgaaa cctatatgca ggtcgcttca
    33181 aaaattttag gaaacccatc tagtctccat cgtttgggag accaagcaac acgaatctta
    33241 gatgcttctc gccaacagat tgcagattta atcggtaaga aaagcgatga aatcttcttt
    33301 acctcgggtg gaacagaagg ggataactgg cttatcaagg gtgtggcctt tgaaaaagct
    33361 cagtttggca agcacatcat tgtttcagcc attgaacatc cagcagtcaa agagtcagcc
    33421 ctctggttga aaagtcaagg atttgaagtg gattttgctc cagttgataa gaaaggcttg
    33481 gtcgatgttg aggcgttagc aggtttgata cggcatgata caatcctcgt ttccatcatg
    33541 gctgtgaaca atgaaatcgg ctctatccaa cctattgagg ctatttcaga attcttggca
    33601 gacaagccga ctatttcctt ccacgttgat gcggttcagg cgcttgccaa aattccgact
    33661 gaaaagtatc tgacagaacg ggtggattgc gcgactttct ctagtcacaa gttccacggg
    33721 gttcgaggtg ttggctttgt ctatatcaaa tctggcaaga agattacacc tcttcttaca
    33781 ggtggtggcc aggagcgaga ttatcgttcg acaactgaaa atgtggcagg gattgcagcg
    33841 acagccaagg ccctccgttt gtctatggaa aagctagata tctttaggag caagactggg
    33901 cagatgaagg cagtgattcg ccaagctctt ctgaactatc cggatatttt tgtcttttca
    33961 gatgaggaaa actttgcacc tcatattctg acttttggaa tcaaaggtgt tcgaggtgaa
    34021 gtcatcgttc acgcctttga agactatgat attttcatct caacaacctc agcttgttca
    34081 tctaaggcag gaaaaccagc cggtaccttg attgccatgg gagtggacaa agataaggcc
    34141 aagtcagctg tgcgtcttag cctagacttg gaaaatgata tgagtcaggt cgagcagttt
    34201 ttgaccaagt taaaattgat ttacaatcaa actagaaaag taagatagga gcattcatgc
    34261 agtattcaga aattatgatt cgctacggag agttgtcaac caagggtaaa aaccgtatgc
    34321 gtttcatcaa taaacttcgt aataatattt cggacgtttt gtctatctat acccaagtta
    34381 aggtaacagc agatcgcgac cgtgcccacg cttacctcaa tggagctgat tacacagcag
    34441 ttgcagaatc tctcaaacaa gtttttggaa ttcaaaactt ttctcctgtt tataaggttg
    34501 aaaaatctgt agaagttttg aagtcttctg tccaagagat tatgcgggac atctacaagg
    34561 aaggtatgac ctttaagatt tctagcaagc gtagcgacca caactttgaa cttgatagtc
    34621 gtgaactcaa ccaaacactt ggaggggctg tattcgaagc cattccaaat gtgcaagttc
    34681 aaatgaaaag tcctgacatc aatcttcagg tggagattcg tgaagaagca gcctatcttt
    34741 cttatgaaac cattcgtggg gctggtggtt tgccagttgg aacttcaggt aaagggatgc
    34801 tcatgttgtc aggagggatt gactcacctg tagcaggtta tcttgctctt aagcgtgggg
    34861 tggatatcga ggcagttcac tttgctagtc caccatatac tagtcctggt gccctcaaga
    34921 aagcgcagga cttgacccgt aaattgacca agtttggcgg aaatatccag tttatcgagg
    34981 tgcctttcac agagattcaa gaggaaatca aagccaaagc gccagaagct tatttgatga
    35041 ctctaactcg tcgctttatg atgcggatta ctgaccgtat tcgtgaggta cgaaatggtt
    35101 tggttatcat caatggggaa agtctaggtc aagtagccag ccaaaccctt gaaagtatga
    35161 aggctatcaa tgctgttacc aacactccca tcattcgtcc tgtggttacc atggacaagt
    35221 tggaaattat tgacatcgcc caggaaatcg atacctttga catttcaatc caaccgtttg
    35281 aagactgttg taccattttt gcaccagatc gtccaaaaac aaatcctaaa attaagaatg
    35341 cggagcagta cgaagcgcgt atggatgttg aaggcttggt tgagcgagca gtggctggaa
    35401 tcatgattac tgaaatcaca cctcaagccg aaaaagatga agttgatgac ttgattgaca
    35461 atctgctcta attcagaaaa tccaaaagaa tagcgaaaat cagtaaaaaa agttagtttt
    35521 ttctctaaaa acaggtaaaa aactaacttt ttttattttt atgatataat gatataaaat
    35581 tttgaatata gagagttttc tgacaatgaa tcaatcctac ttttatctaa aaatgaaaga
    35641 acacaaactc aaggttcctt atacaggtaa ggagcgccgt gtacgtattc ttcttcctaa
    35701 agattatgag aaagatacag accgttccta tcctgttgta tactttcatg acgggcaaaa
    35761 tgtttttaat agcaaagagt ctttcattgg acattcatgg aagattatcc cagctatcaa
    35821 acgaaatccg gatatcagtc gcatgattgt cgttgctatt gacaatgatg gtatggggcg
    35881 gatgaatgag tatgcggctt ggaagttcca agaatctcct atcccagggc agcagtttgg
    35941 tggtaagggt gtggagtatg ctgagtttgt catggaggtg gtcaagcctt ttatcgatga
    36001 gatctatcgt acaaaagcag actgccagca tacggctatg attggttcct cactaggagg
    36061 caatattacc cagtttatcg gtttggaata ccaagaccaa attggttgct tgggcgtttt
    36121 ttcatctgca aactggctcc accaagaagc ctttaaccgc tatttcgagt gccagaaact
    36181 atcgcctgac cagcgcatct tcatctatgt aggaacagaa gaagcagatg atacagacaa
    36241 gaccttgatg gatggcaata tcaaacaagc ctatatcgac tcgtcgcttt gctattacca
    36301 tgatttgata gcagggggag tacatctgga taatcttgtg ctaaaagttc agtctggtgc
    36361 catccatagt gaaatccctt ggtcagaaaa tctaccagat tgtctgagat tttttgcaga
    36421 aaaatggtaa gttaagaaag gaaaaaacga aatgcatatt gaacatctta gccactggag
    36481 tggtcatctt aaccgtgaaa tgtaccttaa ccgttatgga catggtggga ttccagttgt
    36541 ggtctttgct tcatcaggtg gtagtcacaa cgaatactat gattttggca tgattgatgc
    36601 ctgtgcttcc tttatcgagg aaggccttgt ccagttcttt accctatcta gtgtggatag
    36661 tgagagctgg ttggctactt ggaaaaatgc tcatgaccaa gcggaaatgc accgtgccta
    36721 cgaacgttat gtgattgagg aggccattct tttatcaagc acaagacagg ttggtttgat
    36781 ggcatgatga cgacaggttg ctctatggga gcctatcatg cactcaattt cttcctccag
    36841 catccagatg tctttaccaa agtgattgct ctcagtggtg tttacgacgc acgtttcttt
    36901 gtcggtgatt actacaacga tgatgctatt taccaaaact cgccagtaga ttatatttgg
    36961 aaccaaaacg acggctggtt tattgaccgt taccgtcagg cagagattgt gctgtgtacg
    37021 gggcttggag cctgggaaca agatggtttg ccatcctttt acaagctcaa agaagccttt
    37081 gacaagaaac aaattccagc ctggtttgct gaatggggac atgatgtcgc ccatgactgg
    37141 gaatggtggc gtaaacaaat gccttatttc ctcggtaatc tctatttata aaaggagtta
    37201 cctatgaatt accttgttat ttctccctac tatccacaaa actttcaaca gtttaccatc
    37261 gaactagcta ataaaggcat cacagtcttg ggaattggtc aagagtctta cgagcaattg
    37321 gatgagccct tgcgcaatag cttgaccgag tattttcgtg ttgataatct tgagaacata
    37381 gatgaagtca aacgtgcagt tgcttttctc ttttataaac atggtccaat tggccgcatc
    37441 gagtctcaca atgaatactg gcttgagcta gacgcaacac tcagagaaca attcaatgtt
    37501 tttggtgcca aaccagagga tctcaaaaag acgaaatata agtctgaaat gaagaaactt
    37561 ttcaaaaaag caggtgttcc tgtggtacct ggagctgtta tcaagacgga agcagatgtt
    37621 gatcaagcag tgaaagaaat cggtcttcca atgattgcca aacctgataa tggagtggga
    37681 gcagccgcaa cctttaaact tgagacagaa gacgatatca atcacttcaa gcaagaatgg
    37741 gaccattcaa ccctttattt ctttgaaaaa tttgtcactt ccagcgaaat ctgtaccttt
    37801 gacgggctcg tggacaagga tggaaagatt gtcttctcaa caacctttga ctacgcctat
    37861 acaccgcttg acctcatgat ttataagatg gacaattctt attatgtgct caaggatatg
    37921 gatcctaaac tgcgcaagta tggggaagca attgtcaaag aatttggtat gaaagaacgg
    37981 tttttccata ttgagttctt ccgtgagggg gacgattata ttaccatcga gtacaataac
    38041 cgccctgcag gtggttttac cattgatgtt tataactttg ctcattcctt ggacctttat
    38101 cgtggctatg cagctattgt cgcaggagag gagttcccgg cgtcagactt tgaaactcag
    38161 tattgtttgg ctacttctcg ccgtgcaaat gctcactatg tttattcaga agaggatttg
    38221 cttgccaaat atagccagca gttcaaggtt aaaaaagtca tgccagctgc cttcgcggaa
    38281 cttcaaggag attacctgta tatgctgacc actccgagtc gacaagaaat ggagcagatg
    38341 attgcagatt tcggacaacg tcaagaataa gaactatcgg attaaggaaa ttaactccct
    38401 taatcctttt gttttgtctg ataaaaaata agagcatccc aacaaggtag ctatcataaa
    38461 acttgttcga taactatttg aagcaggatt aggtggtcag aaattaaatt ttaatatttc
    38521 aattgagtca tagtattgtg tttgcgtatc cttaaatcag ctaaaaggat ccatgacgac
    38581 acctatacga tatagttttc aagataccaa acaagtctat taatattcaa tgaaaatcaa
    38641 agagcaaact aggaagctag ccgcaggttt ctcaaaacac tgttttgagg ttgtggatag
    38701 aactgacaga gtcagtatca tatacctacg gcaaggtgaa gctgacgtgg tttgaagaga
    38761 ttttcgaaga gtataaaata ttcaggtgac gcatagatat agttaattga agctttgttt
    38821 gaaatctgat aaaataatga tattactaag ttttaaaaac taaagaaaag ggaagatatg
    38881 attacaggtg aattaaaaaa taaaatcgat cagctgtggg aaattctttg gacagaagga
    38941 aacgcaaatc ctttaacaaa tattgaacag ttgacttatc tcttatttat gaaagatttg
    39001 gatagtgtcg agcttggacg tgaaagtgat gctgaatttc tagggattcc ttatgaggga
    39061 gtttttccaa aagataaacc tgaataccgt tggtcaactt ttaaaaatat aggagatgct
    39121 caggaagttt atcgtttaat gactcaggag atttttccgt ttattaaaaa tctcaagggg
    39181 gatacagatg atacagcctt ttcacgatat atgcgagaag ctatttttca aataaataaa
    39241 cctgctacgc ttcaaaaggc aatttctatc ttagatgttt ttccaactag gggattagat
    39301 gtagattttg ataatgacaa acaaagtatt actgatatcg gagatatcta tgaatatctg
    39361 ttatcaaaat tgtcgaccgc aggtaaaaat ggacagttcc gtacatctcg tcacatcatc
    39421 gatatgatgg ttgagttgat gcaaccgact atcaaagata tcatctcaga tcccgctatg
    39481 ggttctgctg gcttcttagt atctgctagc cgttacttaa agcgtaagaa agatgaatgg
    39541 gaaaccaata cagataatat caatcatttt cataatcaga tgtttcatgg aaatgatacg
    39601 gatacgacta tgttgagact tggggcgatg aacatgatgc tacatggagt agaaaatcca
    39661 caaatcagtt accttgactc gctgtctcaa gataatgaag aagccgataa atatactttg
    39721 gttttagcaa atcctccttt taagggctca cttgactaca attcaacctc taatgacctt
    39781 cttgcaaccg taaaaaccaa aaaaacagaa ttactctttc tttctctttt cttgcgaact
    39841 ttaaaaccag gtggacgagc agcagttatc gtacctgatg gtgtcctttt tggttcgtct
    39901 aaagctcata aaggaattcg tcaggaaatt gtagagaatc ataagcttga tgctgtaatc
    39961 tcaatgccta gtggtgtgtt caagccttat gctggagttt caactgccat tctcatcttt
    40021 acaaaaactg gtaatggtgg tactgacaaa gtctggtttt acgatatgaa agcggatggt
    40081 ttaagtttgg atgataagcg acaaccgatt agcgacaatg atattccaga tattatcgaa
    40141 cgctttcatc atcttgaaaa agaagcagaa cgtcagagaa cggatcaatc tttctttgtt
    40201 ccagttgctg agataaagga aaatgattat gatttgtcta tcaataaata taaagagatt
    40261 gagtatgaaa aagttgagta tgaaccaaca gaggtcatct taaagaaaat caatgattta
    40321 gaaaaagaaa ttcaagctgg cttggctgaa ttagaaaaat tactcaagta gagaggtggc
    40381 tgtatgaaaa aagtgaagtt gggggaagtc ttatctctaa aaaaaggcaa gaaagccact
    40441 gtacttgctg aacaaacaac tctaagccaa cgttatattc aaatagatga tttaagaaat
    40501 aataataatt taaaattcac tgaaagttta aatatgactg aagcactccc agatgatatt
    40561 ctgatagcat gggatggagc taatgcagga acagttggtt atggattatc gggagctgtt
    40621 ggtagtacaa ttacggtctt aaaaaagaat gagcgataca aagaaaaaat tatatcagat
    40681 tacttgggag tctttttgga aagtaaatcg cagtatttac gagaacattc aacaggtgca
    40741 acaattcctc atttaaacaa gaatatatta cttgatttac aattagaatt gctaggtatc
    40801 gaagaacaag agaacattat ctgtattctt aatacgatta aaaggcttat tactaaaaga
    40861 aaattgcagt tagatgaact aaacttgctc gtcaaatccc gatttaacga gatgtttggg
    40921 gatcctttaa ataataacaa gaaatttgca gtaaaaacgg gacaacagtg ttttaaattt
    40981 tcaagtggaa aatttcttga taaacatgat agagtttttg aaggttatcc tgcctatggt
    41041 ggaaatggca ttgcttggaa aagtcgaaaa tatttaattg ataatcctac tatcatcatt
    41101 ggtcgtgtag gtgcatattg tggtaatgta agaactaccc acggtaaggt atggataagt
    41161 gacaatgcta tatatataaa agaatttaag aattccgatt tcaatcttgt atttttatta
    41221 gaattaatga aagtaattga ttttagtaaa tttgctgatt tctcaggtca accaaagata
    41281 actcaaaaac cattagaaaa tcagaaatat atcctcctcc cactagccct ccaaaatgag
    41341 ttcgcagact ttgtagccct ggtcgacaaa tcacaatttg cttgtgagat agctataaaa
    41401 gtgtggagaa atagcttgaa atttagtata atatagctaa actatttgtt taaagtgaga
    41461 aaaaaatggg aaattttagc tttcttttaa aaaatgacga atatgaatct ttttcaaaac
    41521 cttgcattga agctgaaaat atgattgcta catcaactgt ggctactgcc tttatggcgc
    41581 gtcgtgcttt ggagcaggct gtccattgga tatatagtca cgattcatat ttagaagctc
    41641 cctatcgtgc tactctatct tctttagtat gggataatga ttttagggat atcgtagatt
    41701 ctgaactcca caagcagata gttctgttga ttcggtgggg aaaccatgct gctcatggtg
    41761 gtgaaattaa ggaacgagaa gcgattttag ctttacatca tttgtatcag tttgttaatt
    41821 ttatcgatta ttgttacagc aatgaatttg tggagcgtta ttttgatgag aagtgcttac
    41881 cactttcagc aaacatcaaa taccgagaaa ctccacaatc tatgataaag ttacaagaca
    41941 gtttaccaga actgcctgat tttcatgaac agatggctgc tcagtccgta gaagttcaag
    42001 agacttatac tgaaaaacgt gagactgcag cgcaacggca agatgtgcct ttccatattg
    42061 aacaattatc tgaggcagag acaagaaagc tctttattga tatcgatctc cgtttagcag
    42121 gatggatatt tgaagaaaac tgtcgtgttg agatagccct tgatggtctc aagcacggtt
    42181 caggaattgg ttactgtgac tatgtacttt atggtaaaaa tgggaaaatt ttagcgattg
    42241 tggaggctaa aaaagcctct gtcaatccag aagtagggga agtacaggtc aaagaatatg
    42301 ctgaagcttt ggagaaacat atcggctatc agccaatttg ctttattaca aatgggttga
    42361 agcactatat acttgatggt ccgaaccgcc gccagattgc aggcttttac tctcaagaag
    42421 aattgcaatt agtgatggat agacgtcatc ttcaaaaacc gcttgaggat atttctagta
    42481 aaattaggga cgatatttcc gggcgtcact accaaaaaca tgccattgca agcgtttgtg
    42541 aagctttctc taatcatcgt agacaggcac ttttggttat ggcaactggg gcggggaaaa
    42601 ctcgtacagc agtttctcta gttgatatct tatcacgtca taactgggta aaaaacgttc
    42661 tcttcttagc cgatagaact tccttggtta agcaagccta tgattcgttt agaaaattac
    42721 tcccagatct ttccgtttgt aacttcttag aagataaaga aggagctcaa tcaagtcgta
    42781 tggtcttttc aacttatccg accatgattg gagcgattag tggtcaagaa gaagtaaatc
    42841 aacgcccttt tactgttggg cattttgacc ttatcataat tgacgaatct caccgttcta
    42901 tttatcagaa atacaagtcc atttttgatt attttgatgc aagaattgta ggcttaacag
    42961 ctactccgcg tcaagattta gataaaaaca cctatggatt ctttaatttg gagaatgggg
    43021 ttccaacata tgcatatgat ttggaagagg ctgttaaaga cggatattta gtagcctatc
    43081 attctatcga aaccaaactg aaactaccta cggatggtct acattatgat gatttgtccg
    43141 aagaagaaaa ggaacatttt gatagcaaat ttgaagacga tagctgtgaa aaagatattg
    43201 atgggagtgt atttaattcc tttattttca ataaaagtac agtagaaatt gttttaaatg
    43261 aactcatgac aagaggaatt cagacagcct cgggtgatga aattggtaaa actattattt
    43321 ttgctaaaaa tcatgatcat gcggaatata tcagaggtat ttttaacaac cgctatcctg
    43381 aaaaagggag cgactatgct caggtgattg attatagtat taagcattat cagaccttga
    43441 ttgatgattt taaaattaag gagaagtatc ctcaaattgc gatttctgtc gatatgttag
    43501 atacaggtat tgatgtacca gaggttgtta atttagtctt cttcaagaaa gtacgctcta
    43561 aaactaagtt ttggcagatg attggtcgag gaacccgtct atgtaaagat ttatttggac
    43621 ctgagcagga taaggaaaac ttcttggtat ttgattatgg ggacaatttt gattattttc
    43681 gtgcagatcc aagagatgga gagggtcgtc acattgtttc gctgactcag cgtttattta
    43741 atatcaaagt ggacttgatt cgagaacttc agggactcca ataccaagaa gatcagtttg
    43801 cgagagcata ccgtcagcag cttgtctcgg aacttcaagg tcgtatagag agcttaaatg
    43861 agttggactt cagggttcgt atggttttag atacagttta tagctatagg aaattggaaa
    43921 gttggcagaa tctaactgct gttacaagtg aaaccattca aaaaaatctc tctccgcttt
    43981 tatttgatga agataaagaa gatgagatgg cgaggagatt tgatttgtgg ttgcttcata
    44041 ttcagttggg gcaactgaca gctaaatctt ccactgttca tatttcccaa gtgatgaaga
    44101 cggctagagc tctttctgct attggcaata tcccgcaggt ttttgagcag gctgaaatta
    44161 tcaggaaagt acaggagcct gaattttgga aagaagttaa cttgtctgat ttggaaaaaa
    44221 ttcgtcttgc tattcgagat ttattacagt ttttggataa aacagaccgt aaaccctact
    44281 atgttaactt tgaagatcgt atactctcca ctgttcacga gaccacagca tttttgcagg
    44341 tcaacgatct tcggtcttac aatgaaaaag ttgagcatta tttgaaaact catctggatg
    44401 aggagtccat ttctaagcta taccataata aaaagttgac atctgatgat atgcttgcac
    44461 ttgaaaaatt gctttgggaa aaattaggta gtaaagcaga ctaccaaagt cattatgaaa
    44521 ataaggcaat tccgagattg gttcgtgaga ttattggctt agatagagag tctgccaatc
    44581 gtattttttc taaatttttg tcggatgaga atcttaatgc caggcagatt tcatttgtaa
    44641 aattgattgt agactacatt gtagaaaatg gttttttaga gacgaaagtg ttaacgcaag
    44701 agccgtttaa atcttatggt tctgttcaac tactcttcca acaccaacta ccagtacttc
    44761 gtaatattgt tcaaatcatt gaacttatca ataatcgagc tggagaagcg gcttaaattc
    44821 taaagtgatt gccatgctga gactcattta aaattaaaaa gagtagaaat ttatgctata
    44881 tatgagaagt tttattagga agaatgtcat cgttttccta gagtacagta tcagttgtta
    44941 agtggttgat aaatttcaaa gtagatactt gtaccacgat gtttgttgat cgagttatta
    45001 acaaaagagc tactttgatt ttaaagaaat agaaaacaaa aagccgagca agaattcaat
    45061 tgcaggagaa aatgaaataa tactcaatga aaatcaaaga gcaaactagg aaactagctg
    45121 caggctgctc aaaacactgt tttgaggttg cagataagac tgacgaagtc agctcaaaac
    45181 atggttttga ggttgtagat gaaactgacg aagtcagtaa ccatacctac ggcaaggcga
    45241 cgttgacgcg gattgaagag attttcgaag agtataaatc ttcctaggat aaagcaaaac
    45301 gcatagtatc aagggttttc aacacttgat actatgcgtt ttctgatgtt aaagactttc
    45361 taccagtttt tttaagcata attgttagtt gtagtcattt attattcttc aaagaaaaat
    45421 ggtggggcga attttttcag ttcttcaaag cacttttgag cagtatctgc atcttcacag
    45481 atgataagac agacatcatt accacaaagg gtagcgatag cgtcagggaa gctcaaagta
    45541 tcaatgatag aaccaaagga ttgagccagt ccaggaaggg tttttagtag gacttggtgt
    45601 tgaactgggc gcatccagac aagggcgtct tccatgtaga gttcgagacg tttttcccat
    45661 tttgagatgg aaccattgtt aagaacataa taagcgctat cttcttcgcg gactttttat
    45721 aggttcatat ttttgatgtc gcgtgagagg gttgcctggg ttacttgaat gtcgttctta
    45781 gcaagaaggg cttgcaactc agcctgtgta tgaatcttgt tttttgtgat aagagcgcgt
    45841 ataagttggt ggcggtgttc tgatttattc ataataatgt aactcctttt agcaaggtaa
    45901 ggtaagcatg gactgagcga ggtcgacagt caagtggtag tctgtattgt cacggatggt
    45961 gatttcaaag tcagtagtat agaggactaa acggagagtg tctccttctt ttagcttgta
    46021 aatagttggc tgcagttcaa attgaacatc catccattca tctgcagtaa tatcctctac
    46081 taacagtaaa tcatttctat tttgtaaatt aaggtaacct tttgtcacga ctcgttgtgc
    46141 ctctggtcta aatggcaatt cacagagatt ttccaacatg tgatagcgac cgttgtcaat
    46201 ggttctagca cttaaaatag ctggataagg ttgtaggtat ttcttttgcc caaattctag
    46261 cagttgggca gataagagcc ccttgtttgt actggatttg atacgaagat tgagctgagc
    46321 gcgaccgttt aggtggagat ctttagtcac aggaaggtta atagtaatct gattggcttt
    46381 cccttgatag agctctgtat tgaaggtttg gtatgtctta ccatagcgct caaaatcctt
    46441 atctgggtac tggttttgaa tagcttgctc ttcttgacca agtgagaagg tttcacagtt
    46501 ttcttgccca ccgaagttat caagtgataa ccaagtctgt ggagctgtat tgtcctgcca
    46561 gataacagta ggaagttgaa agtctgtttc ctgtcctagt aatttcttgg tcaataaggc
    46621 atttatggac tcacggaagt caattgattg ccaattgttc atgtaaacat gggcaccatt
    46681 atggaaaaag agatgcttgt ttatatgagt aggaagagca tggaacatct ggtaaacatg
    46741 aagtggtttg acattccaat cctgagaacc atgagtaaag acaacctctg cctttacttt
    46801 atgggcattg agcagataat tgcggtcatg ccaaaactga ttgtagtccc cagtttttcg
    46861 gtctagctga gctttcactt tttctaagtc agcttggtga gcttcattgc cacggatata
    46921 gtcgccagct aagagattac gagaataggt taactcagca agggagtcaa agtcctcacc
    46981 tggataacca cctgggctag tcaccagacc gttttcacgg tagtagttgt accatgatga
    47041 aattcctgcc tcggcaatga taacttctaa accatcgact cctgtagtcg caagaccatt
    47101 ggacatggta cctagatagg aaagtcctgt tgtagcaact tttccgtttg accaatcagc
    47161 cttgacttga cgctggcgcg tgtgatcagt aaaggcacgg caacggccgt taagccaatc
    47221 gatgacattt gtataagcct cgatttgctg gtagtctcca ttagtcatga aacctgtcga
    47281 gtctttggta ccaacacctg agacatagag attggcaaag cctctcggaa ggaagtagtc
    47341 gtttagtgta tagctagagt tgatgtgagt tagcttttcc tcagcctctg ctataagctc
    47401 agctttacct tggggttgga cgagatttag ttgaggtttc tctagctcaa tcttgtgagg
    47461 aagcttaacc tcaagctcgc cctccatctt gtagagagcc ttgtcactag ccttgtcatt
    47521 ggttccctga tgataagggc tggctgtcat gatggcaggg atttttccat caaaacgagg
    47581 gcgaataatg ctaaccttta ctaggtctga tagccctttt tggtcagtat cgacacgaga
    47641 ctcaacgtaa acgacttcac gaatgacatc ctggttagaa aaagtagcca aactcttgcc
    47701 gttaaagtag tggtagtcat tatcctccgg aataagacca tcactaacaa gttggtcgat
    47761 aagagtattt ccttttttgg tgcgagtatt gagtaactga tagagatttt caatcaagtc
    47821 accatatata atgggaaatc cagtttcttt acgaaaaacg tcactatctt cgaagtcaac
    47881 caaataagaa aagcctaaaa gttgaaaagc aacagtataa aaaatatctg ctgtcagttc
    47941 atcttctgat tgaaaaaatg tcagcaggtc tgttttttta tcagctgcta ggatagaaag
    48001 tgggtagttg gtgtcttgat aagtgaaaaa gaaacgacgt aaaaaggttt caagtgagtc
    48061 tttgtgattg gctgtatttt gtaaatcaaa gccacatttt tttagttcag ataagacatt
    48121 ttcttttgga aaattgatat aactatattg attaaaacgc atagaacctc catatagaat
    48181 gacagttaag gttattatat caaaaaaaaa gcagaaaggg aattgttaac ttcaaaagga
    48241 aataatccaa taaaaatgaa taaagtacta aattcaatat agagaacaga gtaacaataa
    48301 gaataataga tagggtataa aagt
//
LOCUS       DAVLZS010000010        46382 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLZS010000010 DAVLZS010000000
VERSION     DAVLZS010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46382
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.010"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..495
                     /locus_tag="VYO88_000592"
     CDS             <1..495
                     /locus_tag="VYO88_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1718740.1"
                     /translation="NNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGI
                     GLIERVRLGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVK
                     NLDSNYIENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPA
                     KLES"
     gene            complement(484..1288)
                     /locus_tag="VYO88_000593"
     CDS             complement(join(484..918,920..1288))
                     /locus_tag="VYO88_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1718741.1"
                     /translation="MNDEASKQLTDARFKRFVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKELANDSGKKKFHAMKTQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTSRKSSKLKPLTVEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYQNHRKRFGLRMNLIAGIINHELGF"
     gene            1283..1537
                     /locus_tag="VYO88_000594"
     CDS             1283..1537
                     /locus_tag="VYO88_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1718742.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQLKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            1782..3116
                     /gene="trmFO"
                     /locus_tag="VYO88_000595"
     CDS             1782..3116
                     /gene="trmFO"
                     /locus_tag="VYO88_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1718743.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            3200..3937
                     /locus_tag="VYO88_000596"
     CDS             3200..3937
                     /locus_tag="VYO88_000596"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1718744.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            3946..4503
                     /gene="frr"
                     /locus_tag="VYO88_000597"
     CDS             3946..4503
                     /gene="frr"
                     /locus_tag="VYO88_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1718745.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            4563..5417
                     /gene="cvfB"
                     /locus_tag="VYO88_000598"
     CDS             4563..5417
                     /gene="cvfB"
                     /locus_tag="VYO88_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1718746.1"
                     /translation="MNTNLASFILGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            5426..5641
                     /locus_tag="VYO88_000599"
     CDS             5426..5641
                     /locus_tag="VYO88_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1718747.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            5727..6695
                     /locus_tag="VYO88_000600"
     CDS             5727..6695
                     /locus_tag="VYO88_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1718748.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(6673..6852)
                     /locus_tag="VYO88_000601"
     CDS             complement(6673..6852)
                     /locus_tag="VYO88_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718749.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            6888..7388
                     /locus_tag="VYO88_000602"
     CDS             6888..7388
                     /locus_tag="VYO88_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1718750.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            7391..7651
                     /locus_tag="VYO88_000603"
                     /pseudo
     CDS             7391..7651
                     /locus_tag="VYO88_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(8018..8344)
                     /locus_tag="VYO88_000604"
     CDS             complement(8018..8344)
                     /locus_tag="VYO88_000604"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718751.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(8290..8703)
                     /locus_tag="VYO88_000605"
     CDS             complement(8290..8703)
                     /locus_tag="VYO88_000605"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV1718752.1"
                     /translation="MGAHFLTKQAGGSGVLLGGVPGVPKGKVTIIGGGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLMSNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(8704..9129)
                     /locus_tag="VYO88_000606"
     CDS             complement(8704..9129)
                     /locus_tag="VYO88_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV1718753.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            9306..9875
                     /locus_tag="VYO88_000607"
     CDS             9306..9875
                     /locus_tag="VYO88_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1718754.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            9943..10593
                     /locus_tag="VYO88_000608"
     CDS             9943..10593
                     /locus_tag="VYO88_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEV1718755.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            10577..12817
                     /locus_tag="VYO88_000609"
     CDS             10577..12817
                     /locus_tag="VYO88_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1718756.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKTEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGTIRFKGLDSW
                     KIESVR"
     gene            13216..13803
                     /locus_tag="VYO88_000610"
     CDS             13216..13803
                     /locus_tag="VYO88_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718757.1"
                     /translation="MLRLTHVTLKTRQVILQDADFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            13807..14988
                     /locus_tag="VYO88_000611"
     CDS             13807..14988
                     /locus_tag="VYO88_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718758.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVTIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIEKWGSSRKKEVFK
                     V"
     misc_feature    15161..15292
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            15308..15838
                     /gene="infC"
                     /locus_tag="VYO88_000612"
     CDS             15308..15838
                     /gene="infC"
                     /locus_tag="VYO88_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1718759.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            15871..16071
                     /gene="rpmI"
                     /locus_tag="VYO88_000613"
     CDS             15871..16071
                     /gene="rpmI"
                     /locus_tag="VYO88_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1718760.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            16123..16482
                     /gene="rplT"
                     /locus_tag="VYO88_000614"
     CDS             16123..16482
                     /gene="rplT"
                     /locus_tag="VYO88_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1718761.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            16540..16920
                     /locus_tag="VYO88_000615"
     CDS             16540..16920
                     /locus_tag="VYO88_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1718762.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            17170..17970
                     /locus_tag="VYO88_000616"
     CDS             17170..17970
                     /locus_tag="VYO88_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1718763.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHGRGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            17981..18919
                     /locus_tag="VYO88_000617"
     CDS             17981..18919
                     /locus_tag="VYO88_000617"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1718764.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPVIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            18961..20994
                     /locus_tag="VYO88_000618"
     CDS             18961..20994
                     /locus_tag="VYO88_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEV1718765.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(21055..22710)
                     /gene="pavA"
                     /locus_tag="VYO88_000619"
     CDS             complement(21055..22710)
                     /gene="pavA"
                     /locus_tag="VYO88_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1718766.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            22815..23312
                     /gene="ybeY"
                     /locus_tag="VYO88_000620"
     CDS             22815..23312
                     /gene="ybeY"
                     /locus_tag="VYO88_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1718767.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENLELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            23293..23688
                     /locus_tag="VYO88_000621"
     CDS             23293..23688
                     /locus_tag="VYO88_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1718768.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            23705..24604
                     /gene="era"
                     /locus_tag="VYO88_000622"
     CDS             23705..24604
                     /gene="era"
                     /locus_tag="VYO88_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1718769.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMIREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            24653..25477
                     /gene="mutM"
                     /locus_tag="VYO88_000623"
     CDS             24653..25477
                     /gene="mutM"
                     /locus_tag="VYO88_000623"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1718770.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTVAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            25477..26082
                     /locus_tag="VYO88_000624"
     CDS             25477..26082
                     /locus_tag="VYO88_000624"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1718771.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            26069..27268
                     /locus_tag="VYO88_000625"
     CDS             26069..27268
                     /locus_tag="VYO88_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEV1718772.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            27268..27417
                     /gene="rpmG"
                     /locus_tag="VYO88_000626"
     CDS             27268..27417
                     /gene="rpmG"
                     /locus_tag="VYO88_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1718773.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            27457..27690
                     /gene="secG"
                     /locus_tag="VYO88_000627"
     CDS             27457..27690
                     /gene="secG"
                     /locus_tag="VYO88_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1718774.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            27792..30146
                     /gene="rnr"
                     /locus_tag="VYO88_000628"
     CDS             27792..30146
                     /gene="rnr"
                     /locus_tag="VYO88_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1718775.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLCIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNCERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            30109..30576
                     /gene="smpB"
                     /locus_tag="VYO88_000629"
     CDS             30109..30576
                     /gene="smpB"
                     /locus_tag="VYO88_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1718776.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            30592..31452
                     /gene="tehB"
                     /locus_tag="VYO88_000630"
     CDS             30592..31452
                     /gene="tehB"
                     /locus_tag="VYO88_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV1718777.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            31525..32478
                     /gene="coiA"
                     /locus_tag="VYO88_000631"
     CDS             31525..32478
                     /gene="coiA"
                     /locus_tag="VYO88_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1718778.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            32497..34299
                     /gene="pepF"
                     /locus_tag="VYO88_000632"
     CDS             32497..34299
                     /gene="pepF"
                     /locus_tag="VYO88_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1718779.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYVDLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            34301..35014
                     /locus_tag="VYO88_000633"
     CDS             34301..35014
                     /locus_tag="VYO88_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1718780.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGSLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQRLFDATLDNSELTATLVPLG
                     DGILMLRKNVADVQLPDSE"
     gene            35081..36022
                     /gene="prsA"
                     /locus_tag="VYO88_000634"
     CDS             35081..36022
                     /gene="prsA"
                     /locus_tag="VYO88_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1718781.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(36139..36480)
                     /locus_tag="VYO88_000635"
                     /pseudo
     CDS             complement(36139..36480)
                     /locus_tag="VYO88_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            36893..36988
                     /locus_tag="VYO88_000636"
                     /pseudo
     CDS             36893..36988
                     /locus_tag="VYO88_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(37241..37861)
                     /locus_tag="VYO88_000637"
     CDS             complement(37241..37861)
                     /locus_tag="VYO88_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1718782.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(37861..38343)
                     /locus_tag="VYO88_000638"
     CDS             complement(37861..38343)
                     /locus_tag="VYO88_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1718783.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKYLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(38343..39185)
                     /locus_tag="VYO88_000639"
     CDS             complement(38343..39185)
                     /locus_tag="VYO88_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1718784.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(39280..40080)
                     /locus_tag="VYO88_000640"
     CDS             complement(39280..40080)
                     /locus_tag="VYO88_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1718785.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKKETFRKLFLKP"
     gene            40224..41603
                     /gene="glmU"
                     /locus_tag="VYO88_000641"
     CDS             40224..41603
                     /gene="glmU"
                     /locus_tag="VYO88_000641"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1718786.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            41613..42158
                     /locus_tag="VYO88_000642"
     CDS             41613..42158
                     /locus_tag="VYO88_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1718787.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            42170..42484
                     /locus_tag="VYO88_000643"
     CDS             42170..42484
                     /locus_tag="VYO88_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1718788.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            42501..43193
                     /locus_tag="VYO88_000644"
     CDS             42501..43193
                     /locus_tag="VYO88_000644"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1718789.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGTVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            43270..43761
                     /gene="rocS"
                     /locus_tag="VYO88_000645"
     CDS             43270..43761
                     /gene="rocS"
                     /locus_tag="VYO88_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1718790.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            43859..44449
                     /locus_tag="VYO88_000646"
     CDS             43859..44449
                     /locus_tag="VYO88_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1718791.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            44458..46221
                     /locus_tag="VYO88_000647"
     CDS             44458..46221
                     /locus_tag="VYO88_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1718792.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPSLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT        14056 a         8495 c        10279 g        13552 t
ORIGIN      
        1 aataataact ggatagacaa ggaaggcaga gtatttatct attttactgt cgaagaaatt
       61 atgaaaagaa gaaatatctc aaagccaact gccataaaaa cattagatga gcttgatgta
      121 aaaaaaggaa taggactgat cgaaagagta aggcttggac ttggtaagcc gaacatcatt
      181 tatgttaaag actttatgag tatatttcag gtaaaagaaa atgacttaca gaagtcaaaa
      241 aacttaactt cagaagtaaa agattttaac ctcagaagta aagaaaatga acttcaagag
      301 gttaagaacc ttgactctaa ctatatagag aataataaga gtaagtatag taagagagaa
      361 tatagttttg gtgaaaacgg acttggaaca tttcaaaatg tgtttttagc tgctgaagat
      421 atatcggatt tacaaatcat aatgaactca cagcttgaga attacattag acttcctgca
      481 aaactagaat cctagttcat gattgataat accagcaatc aaattcattc gtaatccgaa
      541 gcgtttacga tgattttgat aggttgttga aaacatttta aacgttttta ctttggcaaa
      601 gatgttctca accttgcttc tctccttaga tagcgcatgg ttacaggctt tatcttcaac
      661 tgttagcggc ttgagtttgc tggatttacg tgaagtttgt gcttgaggat atatcttcat
      721 gagcccttga taaccactgt cagccaagat tttaccagct tgtccgatat ttctacgact
      781 cattttgaac aacttcatat catgacaata gttcacagtg atatccaaag aaacaattct
      841 cccttgactt gtgacaatcg cttgagtctt catagcgtga aatttctttt taccagaatc
      901 attcgctaat tcttttttta gggcgattga tttttacttc cgtcgcatca atcattaccg
      961 tgtcctcaga gctgagagga gttcttgaaa tcgtaacacc actttgaaca agagttactt
     1021 caacccattg gctccgacgg agtaagttgc tttcgtgaat accaaaatca gccgcaattt
     1081 cttcataagt tcgatattct cgcacatatt gaagagtagc cataagaagg tcttctaggc
     1141 ttaatttagg ttttcgtcca ccttttgcgt gtttaagttg ataagctgtt tttaatacag
     1201 ctaacatctc ttcaaaagtc gtgcgctgaa caccaacaaa acgcttaaat cgtgcatcag
     1261 ttagttgttt acttgcttca tcattcatag aactactata ccatattttg tttcgcagga
     1321 agtctattgg aaagtaagaa atattgaagc tgaggctatt agaagaaatt gtgagcgtgg
     1381 tgctattttt tcaggtaaaa taaaatatca cgaagattca cagcttaaag gagatcacta
     1441 tgttgaatgt tatgctgttt tagataatac ggttatagca agagatagaa taacagtccc
     1501 tatcgatccg ttatgtggaa aagattttat agagtagcat ataattgatt cttaactgga
     1561 atactcacta tctctttaca tcaagaaaat gactaaacag ggaagtttgc cttcttccct
     1621 ttttttgtta tactagtaga agaaaaaata gaaagatttg tgggagtgaa aaagtcctgt
     1681 ggactttttc agcctgagcc aagaaactcg aaagctcgta agtctgattg gctttttcaa
     1741 tgtgaatctt aacttcacac tcccaaagag gtattagtgt cgtgtctcaa tcttatatca
     1801 atgttatcgg tgctggtttg gcaggttctg aagcagctta ccaaatcgca gagcgtggta
     1861 ttccagttaa actttatgaa atgcgtggtg tcaagtcgac tcctcagcac aaaacagaca
     1921 attttgctga gttggtttgt tccaattctt tgcgtgggga tgctttgaca aatgcagttg
     1981 gtcttctcaa ggaagaaatg cgtcgcttgg gttctgttat cttggaatct gctgaggcta
     2041 cacgtgttcc tgccggtgga gcccttgcgg tggatcgtga tggtttctct caaatggtga
     2101 ccgaaaaagt ggtcaaccac cccttgattg aagtggtgcg tgatgaaatt acagaattgc
     2161 caacagatgt tattacagtt gtggcgactg gtcccttgac tagcgatgcc ctggctgaaa
     2221 agattcatgc ccttaataat ggcgatggct tctatttcta cgatgcagca gcgcctatta
     2281 tcgatgtcaa cactatcgat atgagtaagg tctatctcaa atctcgttat gataagggag
     2341 aagcggccta tctcaatgct ccaatgacca agcaagagtt tatggatttc catgaagcct
     2401 tggtcaatgc ggaagaagca ccgctcaatt cttttgaaaa agaaaagtac tttgaaggat
     2461 gtatgccaat cgaagttatg gccaaacgtg gcattaaaac tatgctttat ggccctatga
     2521 agccagtcgg tcttgagtat ccggacgact acacaggacc tcgtgatgga gaatttaaaa
     2581 caccttatgc ggttgtgcaa cttcgtcagg ataatgcagc tggtagccta tacaatattg
     2641 ttggtttcca gacccacctc aaatggggag aacaaaagcg tgtcttccaa atgattccgg
     2701 gtcttgaaaa tgcggagttt gtccgttatg gtgtcatgca tcgcaattct tacatggatt
     2761 caccaaatct tcttgagcag acttaccgtt ccaagaaaca accaaatctc ttctttgctg
     2821 gtcagatgac gggggtggaa ggctatgttg agtcggcggc ttcgggctta gttgcgggaa
     2881 ttaacgcagc tcgtctcttc aaggaagaaa gcgaggttat tttccccgag acgacagcga
     2941 ttggaagctt agctcattac attacccatg ccgacagcaa acatttccaa ccaatgaatg
     3001 tcaattttgg gatcatcaag gagttggaag gcgagcgtat ccgtgataag aaggctcgtt
     3061 atgaaaaaat tgcagagcgt gcccttgccg acttagagga atttttgact gtctaatttt
     3121 tttgaaagaa ttgttcatga tactataaaa atcgtagaaa ttgtgataaa ataggtagga
     3181 tgaaagaagg agagtgaaaa tggcgaatcc caagtataaa cgtattttaa tcaagttatc
     3241 aggtgaagcc cttgccggtg aacgtggcgt agggattgat atccaaacag ttcaaacaat
     3301 cgcaaaagag attcaagaag ttcatagctt aggtatcgaa attgcccttg ttattggtgg
     3361 aggaaatctc tggcgtggag aacctgcagc agaagcaggt atggaccgtg ttcaggcaga
     3421 ttacactgga atgcttggga ctgttatgaa tgctcttgtg atggcagatt cattgcaaca
     3481 agttggggtt gatacgcgtg tacaaacagc tattgctatg caacaagtgg cagagcctta
     3541 tgtccgtgga cgtgcccttc gtcaccttga aaaaggccgt atcgttatct ttggtgctgg
     3601 aattggttca ccatacttct cgacagatac aacagcggcc cttcgcgcag ctgaaatcga
     3661 agcagatgcc atcctcatgg ctaaaaatgg cgtcgatggt gtgtacaatg ccgatcctaa
     3721 gaaggacaag acagccgtta agtttgaaga attgacccac cgtgatgtta tcaacaaagg
     3781 tcttcgtatc atggactcaa cagcctcaac cctctcaatg gacaacgaca ttgacttggt
     3841 tgtcttcaac atgaaccaat caggcaacat caaacgtgtc gtatttggtg aaaatatcgg
     3901 aacaacagtt tcaaataata tcgaagaaaa ggaataagaa agaatatggc taacgtaatt
     3961 attgaaaaag ctaaagagag aatgacccag tctcaccaat cacttgctcg tgaatttggt
     4021 ggtatccgtg ctggtcgtgc caatgcaagc ttgcttgacc gtatacatgt agaatactat
     4081 ggagttgaaa ctcctcttaa ccaaatcgct tcaattacga ttccagaagc gcgtgttttg
     4141 ttggtaacac catttgacaa gtcttcattg aaagacatcg aacgtgcctt gaacgcttct
     4201 gatcttggta tcacaccagc taatgacggt tctgtgattc gcttggttat cccagctctt
     4261 acagaagaaa ctcgtcgtga ccttgctaaa gaagtgaaga aggtcggcga aaatgctaaa
     4321 gtggctgttc gtaatatccg tcgcgatgct atggacgaag ctaagaaaca agaaaaagca
     4381 aaagaaatca ctgaagacga attgaagact cttgaaaaag acattcaaaa agtaacagac
     4441 gatgctgtta aacacatcga cgatatgact gccaacaaag agaaagaact tttggaagtc
     4501 taaaaataaa cagaaaaact cagttggcat tgctggctga gttttattcg aaagaaggaa
     4561 atatgaatac aaatcttgca agttttatcc ttggactgat catcgatgaa aatgaccgtt
     4621 tttactttgt gcaaaaggat ggtcaaacct atgctcttgc taaggaagaa ggtcaacata
     4681 cagtagggga tacggtcaaa ggttttgcat acacggatat gaagcaaaaa ctccgcctga
     4741 caaccttaga agtgactgcc actcaggacc aatttggttg gggacgtgtc acagaggttc
     4801 gtaaggattt gggtgtcttt gtggatacag gccttcctga caaggaaatc gttgtgtcac
     4861 tcgatattct tcctgagctc aaggaacttt ggcctaagaa gggcgaccaa ctctacatcc
     4921 gtcttgaagt ggataagaaa gaccgtatct ggggcctctt ggcttatcaa gaagacttcc
     4981 aacgtcttgc tcgtcctgct tacaacaaca tgcagaacca aaactggcca gccattgttt
     5041 accgtctcaa gctgtcagga acttttgttt acctaccaga aaataatatg cttggtttta
     5101 ttcatcctag cgagcgttac gcagagccac gtttggggca agtattagat gcgcgcgtta
     5161 ttggtttccg tgaagtggac cgcactctga acctctccct caaaccacgc tcctttgaaa
     5221 tgttggaaaa cgatgctcag atgattttga cttatttgga aagcaatggc ggtttcatga
     5281 ccttaaatga caagtcatct ccagacgaca tcaaggcaac ctttggcatt tctaaaggtc
     5341 agttcaagaa agctttaggt ggtcttatga aggctggtaa aatcaagcag gaccagtttg
     5401 ggacagagtt gatttaggga ggcttatgag aaaatcattt tacacttggc tcatgaccga
     5461 gcgcaatcct aaaagtaaca gtcccaaagc aattttggca gacctcgctt ttgaagaggc
     5521 agcttttcca aaacatacag atgattttga tgaggtcagt cgctttttgg aggagcatgc
     5581 cagtttctct tttaacctag gagattttga cagcatttgg caggaatatc tagaacacta
     5641 gcatttattc attgggtttg ggctagtaat ttctccatcc ctctgctata ataaaaagaa
     5701 ataaaaggat tagagaggtt ctttatttga aggaacattc aatagacatt caactgagtc
     5761 atccagatga cctgtttcat ctttttggtt ccaatgagcg ccatcttcgt ttgatggaag
     5821 aagagctgga tgtggtgatt catgctcgta cggagattgt ccaggttttg ggagaagagt
     5881 ctgcttgcga ggaagcccgt caggttattc aagctctcat ggccttggtg aaccgtggga
     5941 tgaccgttgg tacgccagat gtggtgactg caattagcat ggtcaaaaac gatgaaattg
     6001 ataagtttgt cgccctttac gaagaagaaa ttatcaagga taatactggg aaaccgatcc
     6061 gcgttaaaac gttaggtcaa aaactttatg tggacagtgt caaacagcat gatgtgacct
     6121 ttggaattgg gcctgcaggg acggggaaga cctttcttgc agttactttg gcagtgactg
     6181 cccttaaacg tgggcaagtc aagcggatta tcttgacacg tccagcggtg gaagcaggag
     6241 agagtctagg ttttcttccg ggtgatctta aggagaaggt agatccttac cttagacctg
     6301 tttatgatgc cttgtatcag attcttggga aagaccaaac gactcgtctc atggagcgtg
     6361 aaattatcga aattgcgccc cttgcctata tgcgtggccg gaccttggat gatgcctttg
     6421 tcattctcga tgaggcgcaa aacacgacca tcatgcagat gaagatgttc ttgacgcgtt
     6481 taggctttca ttctaagatg attgtcaatg gagatatcag tcagattgac ctgccacgta
     6541 atgtcaagtc cggtttgatt gatgctcaag agaaactcaa gaacatccat cagattgact
     6601 ttgttcattt ttcagccaag gatgtggttc gccatccagt tgtcgctcag attatccgag
     6661 cctatgaata ttctactgaa gttgcacacg actgattttg aggaagttcg cctgcaaaag
     6721 aatatacttt tgagagagga aaatccagtt gtataggcta aaggttttat ccaaaggtct
     6781 gagacaacga ttaggcacga tggaaagaac ttttatgtgg ctgatgacga tcagtgcatc
     6841 ttcctgtgtc ataatcacag ggcacaagaa agtaggaatt tgaaaagatg attgaccaac
     6901 tatctaagta ttacagttgt aggatactaa ctgaaaagga tattccaagt attttatctt
     6961 tatatgaaag taatcctctg tattttcagc attgtccacc agaaccaaat tttgcaactg
     7021 taaaagagga catgctttgt ctacctgaag gtaaagctaa ggctgataag ttttttgttg
     7081 gattttggaa tggatctgac cttgtggctg ttatggattt tgtctatgca tatcctgatg
     7141 aggagactgt ttttattggt ttgtttatgg ttgatcaagc ctatcagagg aaagggattg
     7201 gtagtcatat tgtgacagaa gcactagctt attttgctaa gaactttcga aaggcacgtt
     7261 tggcttatgt taagggaaat ccgcaatctc agcatttttg ggaaaagcag ggctttaaat
     7321 caattggatg cgaggttaag caagaactct atacggttgt tatcgctgaa cagagcctag
     7381 aagattagaa atggcatcaa gtaagaacta tttggaattt gttttggaac aattatcagg
     7441 attagatgat gtgacttacc gttccatgat gggggagtat attctttact tccgcggcaa
     7501 gattattggc ggcatttatg acgatcgctt tttagttaaa cccgtgcaag cagtcttaga
     7561 taagattgac caatcttctt ttgagtttcc atacaaaggt gccaaagaaa tgatttgagt
     7621 ggaagaactt gataataaga tgtttctata agacctgatt ttagctatgt ataaccaact
     7681 gccaacgccc aaacctaaaa agaaaaagca agggtgaacg aagtaaaaaa gaagtctgct
     7741 aaggccctgt ctttgcacgg gtaaaatttt atatataaaa agaagctggg actaaagagc
     7801 tcagcttcct ttggtttata taattgtcat tacaagacga agtggttggg cgaaactctg
     7861 ttgactttat tcaatttaga gtttcttatg cacaattgag tctggaacga aagtctccag
     7921 ttgcaaagta tacagtacaa taaaccaacg atgtaatagc tgatgacaca aagcacagtg
     7981 ggtaggactt gcgaagtcac ccttttcttt tcaaaattta tactaaatca ttgatatcag
     8041 tgtagtcacg attaagtcct tgagcaactg gtaggctagt caagtaacct tgataagtgg
     8101 tcacaccttg acgcaagcct tcatcttcag agattgcttg tgcgaatcct ttgccagcca
     8161 aagcttcgat ataaggaaga gtgacattgg ttagggcgat ggttgaagtg cgggcaaccg
     8221 caccagggat attggcaacg gcatagtgga gaacaccgtg tttttcatag acgggttcat
     8281 cgtgcgttgt cacacggtca gctgtttcga taacgccacc ttggtcaaca gcaacgtcaa
     8341 cgatacagag cctggacgca tttgtttgac catctcatct gtcaccaatt ccggtgcttt
     8401 tgcaccaggg atgagaatgg ctccaatcac cacatcagca tctctcacac ttgcttcaat
     8461 gttgaatgaa ttagacataa gagtttgaat ttgacttcca aagacttctt ctagaactga
     8521 gagacgcttg gcactaatat ctaaaatagt cacttgagca ccaagaccaa gggcgatgcg
     8581 ggcagcatgt gtaccgacga caccaccacc gatgatagtt acttttcctt ttggaacacc
     8641 tggtacacca ccaagtagaa caccagagcc accagcttgc ttagtaagga agtgagctcc
     8701 gatttaaaca gccatacgac ctgcaacctc actcatagga acgaggagcg gtagttgtcc
     8761 ttgattgtca cgaacagttt cataggcaat tcctgttgtt tttgctgcta acatagcatc
     8821 tgctaattct ggagcagcgg ccatgtgcaa gtaggtgaag agaagaagat cgtcgcgcaa
     8881 gtaaccgtat tcagaactta aaggttcttt tactttcaca accaactctg ctgcccaagc
     8941 ttcaccagca gtagcgacaa tctcagctcc ttgcttttga tagtcagcat cagtaaagcc
     9001 agaaccgaga ccagcatttg tttcgataag gacacgatga ccacgactaa ctaagctatg
     9061 aacacctgca ggtgtgaggg cgacacggtt ttcgttattt ttaatttctt ttgggattcc
     9121 gattaacatt gagataacct acctttcaat tgacggtctt gttttggttg tcacattcca
     9181 gttcataaat caaaaatgtg acggtttcat tgtatatgaa accgcttcaa aaatcaagaa
     9241 aaacttgtca tcccaatttt tttatgctag actagtgaaa atcaagctct aatggaggga
     9301 aaagtatgga atcaatattt gtgaaatttg cccagtatcc gtctatagaa acggagcgtt
     9361 tattgcttag acctgtaact ttggatgatg cggaagcaat gtttgactat gcctcggaca
     9421 agggtaatac acgttacact tttccaacca atcaaagctt ggaagaaacc aagaataaca
     9481 ttgctcagtt ctacttggct aatcccttgg gacgttgggg aatagaacta aaaagcaatg
     9541 gtcagtttat tggaaccatt gacttacaca agattgatcc tgttcttaag aaggcagcta
     9601 ttggctacat tatcaataaa aagtattgga atcaaggatt aacgacagaa gccaatcgtg
     9661 ctgtgattga gctagctttt gagaagatag ggatgaataa gttgactgcc cttcacgata
     9721 aggctaatcc cgcgtcagga aaggtcatgg agaaatcagg catgcgtttt tcccatgcag
     9781 aaccatatgc ttgtatggac cagcatgaaa aaggccgaat cgtgacaaga gttcattatg
     9841 tcttgaccaa ggaagactat tttgcaaata aataagcagt tgaaaagaaa tttttcgact
     9901 gttttttctt cctcttacga ataatctaag agaggagaaa atatggaagc aattatcgag
     9961 aaaatcaaag agtataaaat catcgtcatc tgtactggtc tgggcttgct tgtaggagga
    10021 tttttcctgc taaaaccagc tccacaaaca cctgtcaaag agacgaattt gcaggctgaa
    10081 gttgcagctg tttccaagga ctcatcgacc gaaaaggaag tgaagaagga agaaaaggaa
    10141 gaaccccttg aacaagatct aatcacagta gatgtcaaag gtgctgtcaa atcgccaggg
    10201 atttatgact tgcctgtagg tagtcgagtc aatgatgctg ttcagaaggc tggtggcttg
    10261 acagagcaag cagacagcaa gtcgctcaat ctagctcaga aagttagtga tgaggctctg
    10321 gtttacgttc ctactaaggg agaagaagca gttagtcaac agactggttc ggggacagct
    10381 tcttcaacaa gcaaggaaaa gaaggtcaat ctcaacaagg ccagtctgga agaactcaag
    10441 caggtcaagg gactgggagg aaaacgagct caggacatta ttgaccatcg tgaggcaaat
    10501 ggcaagttca agtcagtaga cgagctcaag aaggtctctg gcattggtgc caagaccata
    10561 gaaaaactta aagactatgt tacagtggat taagaatttc tctattcccc taatttacct
    10621 gagttttctg ttactatggc tttactacgc cattttctca gtatcctatt ttgctttgtt
    10681 gggttttgtt tttctgctag tctgcctctt tatccaattt ccttggaaat cagcaggtaa
    10741 agttctagtg atttgtggag tctttggctt ctggtttctg tttcaaactt ggcaacagag
    10801 tcaagcgagt caaaatctgg cggattctgt tgaaagggta cggattttgc ctgatactat
    10861 taaggttaat ggtgatagtc tatcctttcg tggcaagtct aacggtcgtg ctttccaagt
    10921 ctattataaa ctccagtccg aggaggagaa agaagccttt caagctttaa ccgacctgca
    10981 tgagatagga ctagaaggga agctttcgga gccagaaggg cagagaaatt ttggtggctt
    11041 taattaccaa gcctatctga agactcaggg aatttaccag actctcaata tcaaaacaat
    11101 ccagtcactt caaaagattg gcagttggga tataggagaa aacttgtcca gtttacgtcg
    11161 aaaggctgtg gtttggatta agacgcactt tccagaccct atgcgcaatt acatgacagg
    11221 actcttgctg ggacatctgg acaccgactt tgaggagatg aatgagcttt attccagtct
    11281 aggaattatc cacctctttg ccctatctgg tatgcaggta ggttttttca tgaatggatt
    11341 taagaaactt ctcttgcgat tgggcttgac ccaagaaaag ttgaaatggc tgacttatcc
    11401 cttttccctt atctatgcgg gactaactgg attttcagca tcggttattc gcagtctctt
    11461 gcaaaagtta ctggctcaac atggggttaa gggcttggat aattttgcct tgacggtgct
    11521 tgtcctcttt attgtcatgc caaacttttt cttgacagca ggaggagtct tgtcctgcgc
    11581 ttatgctttt atcctgacca tgaccagcaa agaaggggag gggctcaagg ctgttactag
    11641 tgaaagtcta gtcatctcct tgggcatatt gcccattcta tccttctatt ttgcggaatt
    11701 tcaaccttgg tctatccttt tgacctttgt cttttccttt ctatttgact tgaccttctt
    11761 accgctcttg tctattttat ttgtcctttc ctttctctat ccagtcattc agctgaactt
    11821 tatctttgaa tggttggagg gcattattcg cttggtgtca caggtgacaa gtagacctct
    11881 ggtctttgga caacccaatg catggttttt aatcctattg ttaatttcct tggctttggt
    11941 ctatgatttg agaaaaaaca ttaaaaagct aacggtattg tgcttattga ttacagggct
    12001 ctttctcctg accaagcatc cactggaaaa tgaaatcacc atgctggatg tggggcaagg
    12061 agaaagtatt ttcctacggg atgtaactgg gaaaaccatt ctcatagatg taggtggtaa
    12121 ggcagaatct tataagaaaa ccgaaaaatg gcaagaaaag atgacgacca gcaatgcaca
    12181 gagaagcttg ataccctatc ttaaaagtcg aggagtagct aagattgacc agctgatttt
    12241 gacaaatacg gacaaggaac atgtcggaga tttgttagag gtgaccaagg ctttccatgt
    12301 aggggagatt ctagtatcaa aaggcagttt gaagcagaag caatttgtgg tagaactaca
    12361 ggcgactcaa acaaaggtgc gtagtatgat agtaggggag aacttgccca tttttggaag
    12421 tcagttagaa gttctatctc caaggaaaat gggagatgga ggacacgatg ataccctagt
    12481 tctgtatggg aaattcttgg ataagcaatt tctcttcacg ggaaatttgg aggagaaagg
    12541 agagaaggac ttgctgaagc actatccaga cttgaaagta aatgttttga aagctagcca
    12601 acatggcaat aaaaaatcat caagtccagc ctttctagaa aaactcaaac cagagcttac
    12661 tcttatctca gttggaaaga gcaatcgaat gaaactcccc catcaggaaa cattgacacg
    12721 actggaaggt atcaatagca aagtttatcg aactgaccag caaggaacta tacgttttaa
    12781 ggggttggat agttggaaaa tcgaaagtgt tcgataggaa agataaatgt tgtagattag
    12841 tgaaataaac taaaaatttg ttgcataata atgataaaaa tggtataatg aaaacgtatt
    12901 caatattgag gatataaaat cattaaaaat cagcaaaagt tattttatta gttagtttat
    12961 aatctattgg tcttcttcag tccagtgtat ctgctaagag tgttcttaaa agtatcggta
    13021 tgattggaat atcttctata agtctagtat gaatttccat ggatatagac atactaacgt
    13081 tccgtcatgg tctcgttatt acagctattc tgagtatcca gttggttctg gctggaacta
    13141 cggtcgttat gagatcataa actattacag cggaggatat taatagttaa acgtttagaa
    13201 gaaggagagt ttgatatgtt aaggcttact catgttaccc taaaaacgcg acaagtcatc
    13261 ttgcaagatg cggatttcac ctttaaaaag ggtagggttt atggtcttct tgctatcaat
    13321 ggctctggaa agacgaccct gttccgtgcc attagcaatt taattcccat aagtagtgga
    13381 aatatcgcag cccctccttc tttattttat tatgagagcg ttgaatggct ggatggaaac
    13441 ttaagtggga tggactacct tcgtcttatc aaaaacatct ggaagtcagg tctgaacttg
    13501 agggatgaaa tcgcctattg ggaaatgtct gactatatca gtcttcccat tcgcaagtat
    13561 tccttaggca tgaagcaacg cttggtgatt gccatgtatt tcctcagtca ggccaaatgc
    13621 tggctcatgg atgagattac aaatggctta gatgagtatt atcgacagaa gttttttgat
    13681 aggctagcac aaatcgatag acaagaacag ctggttcttt taagttccca ctataaggaa
    13741 gagttggttg atgtctgcga tagagtagta accattcatc aggggcagat agaagaggtt
    13801 tagtttatga aagatgttag tctattttta ttgaaaaaag ttttcaaaag ccgcttaaac
    13861 tggattgtct tagctttatt tgtatctgta ctcggtgtta ccttttattt aaatagtcag
    13921 actgcaaact cacacagctt ggagagcagg ttggaaagtc gcattgcagc caacgagagg
    13981 gctatcaatg aaaatgaaga gaaactctcc caaatgtctg ataccagctc ggaggaatac
    14041 cagtttgcta aaaataattt agacgtgcaa aaaaatcttt tgacgcgaaa gacagaaatt
    14101 ctaactttac taaaagaagg gcgctggaaa gaagcctact atctgcagtg gcaagatgaa
    14161 gagaagaatt atgaatttgt atcaaatgac ccgactgcta gctctggctt aaaaatgggg
    14221 gttgaccgcg aacggaagat ttaccaagcc ctgtatccct tgaacataaa agcacatact
    14281 ttggagtttc cgacccacgg gattgatcag attgtctgga ttttagaggt tatcatccca
    14341 agcttgtttg tggttactat tatttttatg ctaacacaac tatttgcaga aagatatcaa
    14401 aatcatctgg acacagctca cttatatcct gtttcaaaag tgacatttgc aatatcctct
    14461 cttggagttg gagtgggata tgtaactgtg ctgtttatcg gaatctgtgg cttttctttt
    14521 ctagtgggaa gtctgataag tggttttgga cagttagatt atccctaccc aatttatagc
    14581 ttagtgaatc aagaagtaac tattgggaaa atacaagatg tattatttcc tggcttgctc
    14641 ttagctttct tagcctttat cgtcattgtg gaagttgtgt acttgattgc ttactttttc
    14701 aagcaaaaaa tgcctgtcct ctttctttca ctcattggga ttgttggctt attgtttggc
    14761 atccaaacaa ttcagcctct tcaaaggatt gcacatctga ttccctttac ttacttgcgt
    14821 tcagtggaga ttttatctgg aagattatct aagcagattg ataatgtcga tctaaattgg
    14881 agcatgggga tggtcttact tccttgcctg attatccttt tgttagtggg gattctattt
    14941 atcgaaaaat ggggaagttc acgtaaaaag gaagttttta aagtttagtt ttcctatagg
    15001 gaaggtgagg aaaaaactaa cagagtgagg gaaccaacta ggttctctct ttttgattcg
    15061 aaaaccaaac caaaatacaa acacaaacac aaacacaaac ttttcaaaaa ataacttttt
    15121 atcttgacaa gagctagaaa acttggtatc atataaaagt tgagaaaagc agaagtgaga
    15181 gcttctcgcc ttgtgacatt aagttgcctg gccctacgga tgaaaagttt cgaagaaacg
    15241 ctatcataac gtgcgggctt gtatatttac gagtccgcta ttgtttttct ctaataaaac
    15301 aaaagaggtg aaaaccatag caaagcaaga cttattcatc aatgatgaga ttcgtgtacg
    15361 tgaagttcgc ttgattggtc ttgagggaga acagctaggc atcaagccac tcagtgaagc
    15421 gcaagctttg gctgataacg ctaatgttga cctagtattg attcaacccc aagccaaacc
    15481 gcctgttgca aaaattatgg actacggtaa gttcaaattt gagtaccaga agaagcaaaa
    15541 agaacaacgt aaaaaacaaa gcgttgttac tgtgaaagaa gttcgtctaa gtccaactat
    15601 tgacaagggt gactttgata caaaacttcg taatgcacgt aagttccttg aaaaaggaaa
    15661 taaagttaag gtatctattc gctttaaggg tcgtatgatt acccataaag agattggtgc
    15721 aaaagtttta gccgagtttg ctgaagcaac tcaagatatt gccatcatcg aacaacgtgc
    15781 taaaatggat ggacgtcaaa tgttcatgca attggcgcca gcgactgaca aaaaataatt
    15841 gtcagaaagt taaataaagg agaaaaaatc atgccaaaac aaaaaacaca ccgcgcatca
    15901 gctaaacgtt tcaaacgtac aggttctggt ggacttaaac gtttccgtgc ttacacttct
    15961 caccgtttcc acggaaaaac caagaaacaa cgtcgtcatc ttcgtaaagc atctatggtg
    16021 cattcaggag attacaaacg tatcaaagca atgcttactc gcttgaaata atagcttgac
    16081 tgtaagtaaa caattctagg aaatatttgg aggaaataaa atatggcacg tgttaaaggt
    16141 ggcgttgtat cacgcaaacg tcgtaaacgt attcttaaat tagcaaaagg ttactatgga
    16201 gctaaacaca tcttgttccg tactgcaaaa gaacaagtaa tgaactctta ctactatgca
    16261 taccgtgacc gtcgtcagaa aaaacgtgac ttccgcaaat tgtggattac tcgtatcaat
    16321 gcggcagctc gtatgaacgg actttcatac tcacaattga tgcatggttt gaaattggct
    16381 gagatcgaag ttaaccgtaa aatgcttgct gacttggctg ttaacgatgc agtagctttc
    16441 acagctcttg cagatgcagc taaagcaaaa cttggtaaat aacaactgat gagactggaa
    16501 caggattgtc cagtcttttt aaaaataaag gagaaaagta tggcttcaaa aatgctacac
    16561 acttgcttac gagtagaaaa tcttgaaaaa tcaattgcat tctatcaaga tgcttttggt
    16621 tttaaagaat tgcgtcgcag agattttcca gaccatgcct tcacgattgt ctatctaggt
    16681 cttgagggtg atgattatga gttggagttg acttataact acgatcacgg tccgtatgtg
    16741 gttggtgatg ggtttgccca tatcgccctc agtacacctg atcttgaggc acttcatcaa
    16801 gaacacagtg caaaaggcta tgaagtgact gagccaaatg gtctaccagg aactacacca
    16861 aactattact ttgtcaaaga ccctgatgga tataaggtcg aagtcattcg tgaaaaataa
    16921 tttcgtgcaa gttaagtaga atattcgttt tctacttgac tttttttagc tgaaagagta
    16981 tactaataaa aattcaacct ttaaggggag tccagagaga ctcacaaggt gtcagataaa
    17041 agaatagtgc aattttctag aggagacttt ttgagtgtgc tctcttgtgt tgtacgattt
    17101 taactgaggc cttgcactag caaggtcttt tctttatctg gtccccttaa aatttaagga
    17161 ggaaaagtta tgaatcccac atgtaagaag cgtttgggtg tcattcggtt ggaaaccatg
    17221 aaggtggttg cacaagagga aatcgcgcca gcaatctttg aattagttct agaaggagaa
    17281 atggttgaag ccatgcgagc aggccaattt cttcatctgc gtgtaccgga cgatgcccat
    17341 ctcttacgtc gtcctatttc aatttcgtct attgacaagg caaacaagca gtgtcacctc
    17401 atttatcgga ttgagggagc tgggactgca attttttcaa ccttaagtca gggagacact
    17461 cttgatgtga tggggcctca gggaaatggt tttgacttgt ctgaccttga tgagcagaat
    17521 caggttctcc ttgttggtgg tgggattggt gttccaccct tgcttgaggt ggccaaggaa
    17581 ttgcatggac gtggagtgaa agtagtgaca gtcctcggtt ttgctaataa ggatgctgtt
    17641 attttgaaaa cggaattggc tcagtatggt caggtctttg taacgacaga tgatggttct
    17701 tatggcatca agggaaatgt ttccgttgtt atcaatgatt tagatagtca gtttgatgct
    17761 gtttactcgt gtggggctcc aggaatgatg aagtatatca atcaaacctt tgatgatcac
    17821 ccaagagcct atttatctct ggaatctcgt atggcttgtg ggatgggagc ttgctatgcc
    17881 tgtgttctaa aagtaccaga aagcgagacg gtcagccaac gcgtctgtga agatggtcct
    17941 gttttccgca caggaacagt tgtattataa ggagaaaatt atgactacaa atcgattaca
    18001 agtgtctcta cctggtttgg atttgaaaaa tccgattatt ccagcatcag gctgttttgg
    18061 ctttggacaa gagtatgcca agtactatga tttagacctt ttaggttcta ttatgatcaa
    18121 ggcgacaacc cttgaaccac gttttgggaa tccaactcca agagtggcag agacgcctgc
    18181 tggtatgctc aatgcaattg gcttgcaaaa tcctggttta gaggttgttt tggctgaaaa
    18241 gctaccttgg ctggaaagag aatatccaaa tcttcctatt attgccaatg tagctggttt
    18301 ttcaaaacaa gagtatgcag ctgtttctca tgggatttcc aaggcaacta atgtaaaagc
    18361 tatcgagctc aatatttctt gtcccaatgt tgaccactgt aatcatggac ttttgattgg
    18421 tcaagatcca gatttggctt atgatgtggt gaaagcagct gtggaagcct cagaagtgcc
    18481 agtttatgtc aaattaaccc cgagtgtgac cgatatcgtt actgtcgcaa aagctgcaga
    18541 agatgcggga gcaagtggct tgaccatgat caatactctg gttggaatgc gctttgacct
    18601 caaaactaga aaaccaatct tggccaatgg aacaggtgga atgtcaggtc cagcagtctt
    18661 tccagtagcc ctcaaactca tccgccaagt agcccaaaca acagacctgc ctatcattgg
    18721 aatgggggga gtggattcgg ctgaagctgc cctagaaatg tatctggctg gggcatctgc
    18781 tatcggagtt ggaacagcta actttaccaa tccttatgcc tgtcctgtca tcatcgaaaa
    18841 tttaccaaaa gtcatggata aatacggtat tagcagtctg gaagaactcc gtcaggaagt
    18901 aaaagagtct ctgaggtaaa ctgcaatcaa tctgttcttg attttttatt agtttgtaat
    18961 atgaatttag gagaattttg gtacaataaa ataaataaga acagaggaag aaggttaatg
    19021 aagaaagtaa gatttatttt tttagctctg ctatttttct tagctagtcc agagggtgca
    19081 atggctagtg atggtacttg gcaaggaaaa cagtatctga aagaagatgg cagtcaagca
    19141 gcgaatgagt gggtttttga tactcattat caatcttggt tctatataaa agcagatgct
    19201 aactatgctg aaaatgaatg gctaaagcaa ggtgacgact atttttacct caaatctggt
    19261 ggctatatgg ccaaatcaga atgggtagaa gacaagggag ccttttatta tcttgaccaa
    19321 gatggaaaga tgaaacgaaa tgcttgggta ggaacttcct atgttggtgc aacaggtgcc
    19381 aaagtaatag aagactgggt ctatgattct caatacgatg cttggtttta tatcaaagca
    19441 gatggacagc acgcagagaa agaatggctc caaattaaag ggaaggacta ttatttcaaa
    19501 tccggtggtt atctactgac aagtcagtgg attaatcaag cttatgtgaa tgctagtggt
    19561 gccaaagtac agcaaggttg gctttttgac aaacaatacc aatcttggtt ttacatcaaa
    19621 gaaaatggaa actatgctga taaagaatgg attttcgaga atggtcacta ttattatcta
    19681 aaatccggtg gctacatggc agccaatgaa tggatttggg ataaggaatc ttggttttac
    19741 ctcaagtttg atggcaaaat ggctgaaaaa gaatgggtct acgattctca tagtcaagcc
    19801 tggtactact tcaaatccgg tggttacatg acagccaatg aatggatttg ggataaggaa
    19861 tcttggtttt atctcaaatc tgatgggaaa atagctgaaa aagaatgggt ctacgattct
    19921 catagtcaag cttggtacta cttcaaatcc ggtggttaca tgacagccaa tgaatggatt
    19981 tgggataagg aatcttggtt ttacctcaag tctgatggca aaatggctga aaaagaatgg
    20041 gtctacgatt ctcatagtca agcctggtac tacttcaaat ctggtggcta catggcgaaa
    20101 aatgagacag tagatggtta tcagcttgga agcgatggta aatggcttgg aggaaaagct
    20161 acaaataaaa atgctgctta ctatcaagta gtgcctgtca cagccaatgt ttatgattca
    20221 gatggtgaaa agctttccta tatatcgcaa ggtagtgtcg tatggctaga taaggataga
    20281 aaaagtgatg acaagcgctt ggctattact atttctggtt tgtcaggcta tatgaaaaca
    20341 gaagatttac aagcgctaga tgctagtaag gactttatcc cttattatga gagtgatggc
    20401 caccgttttt atcactatgt ggctcagaat gctagtatcc cagtagcttc tcatctttct
    20461 gatatggaag taggcaagaa atattattcg gcagatggcc tgcattttga tggttttaag
    20521 cttgagaatc ccttcctttt caaagattta acagaggcta caaactacag tgctgaagaa
    20581 ttggataagg tatttagttt gctaaacatt aataatagcc ttttggagaa caagggcgct
    20641 acttttaagg aagccgaaga acattaccat atcaatgccc tttatctcct tgcccatagt
    20701 gccctagaaa gtaactgggg aagaagtaaa attgccaaag ataagaataa tttctttggc
    20761 attacagcct atgatacgac cccttacctt tctgccaaga catttgatga tgtggataag
    20821 ggaattttag gtgcaaccaa gtggattaag gaaaattata tcgatagggg aagaactttc
    20881 cttggaaaca aggcttctgg tatgaatgtg gaatatgctt cagaccctta ttggggcgaa
    20941 aaaattgcta gtgtgatgat gaaaatcaat gagaagctag gtggcaaaga ttagtactat
    21001 aagtgaatat gatttgagtg aatagtaagt taaaaatcct gatttcaagt aaaatcagga
    21061 ttttttcatg gatgcaattt ttttggagtc tggtgtgacg cggagggtct tttgtcctgt
    21121 gtaagtgaca aagccgggtt ttccaccagt tggtttattg agttttttga cttcaatcat
    21181 atctacctgc accagattcg acaggcgccc ttgagagaag taggcagcta actctgctgc
    21241 gtctgtcttg actgcatcag atgggtcaag atttcctgag atgacaacat ggcttccagg
    21301 aatgtcctta gcatggaacc aaagttcctc cttgcgggcc attttaaagg tcaattcctc
    21361 attttgaaga ttgtttcgtc cgacatagat gatggttttg ccatcgcttg ctagatattg
    21421 ttctagtttt ttgcgtttct ggattttctc ccgttgtctt ctgcggataa aacctgtttg
    21481 aatcaattct tcacggattt cagcgatttc ttccagtcca gcttggttga ggacggtttc
    21541 tacactttcc agatagagaa tagtggcttt ggtttcttca atcaaatcag tcaagtattt
    21601 gacagcttct ttgagtttct gataccgttt aaaatagcgt tgggcattct ggttgggagt
    21661 cagagcctta tcaagcgcaa tcatgatagg ttggttggta tagtagttgt ctaggataac
    21721 ctggtcttgg tcgttaggca cttggtgtag gaaggttgtc agcaattctc ctttttgacg
    21781 aaattcttca gcgttgtctg tcgccagtaa ctctttttcc tgttttttga gtttgtgtcg
    21841 gtttttctga agttcatttt caacacgacg aatcagttca ctggcctgct gtttgacgcg
    21901 gtcgcgctca gccttatcct tatagtaggt gtccaacaaa tcagaaagat ttgcaaaagg
    21961 ctctcccacc tgatttgcaa aaggaactgg actgaaggaa gtctcagtca agcatggctt
    22021 ggtttcttga ttgaaaaaat ttcggaaagc ggaaagtttt tcactaacca gtatcctttc
    22081 caattcattt gccgtatcgc gtcccagacc ttgaaagagg ctttgaagat tttttgctgt
    22141 tagttcttgg gtttgcagga tttcaaagag cttttcatcc ttgatagtaa aaggattgag
    22201 agattttgta cttggcggag cgatataggt cgatcctgga agtaaggtgc ggtagctatt
    22261 ttgtgaaaag ccgacgtgtt tgataacttc gaggatttta tgactgcttt tatcgaccag
    22321 tagaatatta ctgtgtttcc ccataatttc gataatcaag gtagcctgga tatggtctcc
    22381 aatctcgttt ttattggaaa ctgtaatttc cacaatacgg tcattttcca cttgctcaat
    22441 cgactcaatc agggccccct gcaaatactt tctcaaaacc atgataaagg tagaaggttg
    22501 ggctggattt tcaaaagtcg tttgggttag ctgaatgcgt ccaaaaactg gatgggcaga
    22561 aaggagcagg cgatggcttt ggcgattgct gcggatttgc aagaccaact cttgttcaaa
    22621 aggctgattg attttctgga tgcgaccatt cactaattcg cttcgcaatt cctcaactat
    22681 gtggtgtaaa aaaaatccgt caaatgacat cgttctctcc ttgtgattgt attccatagt
    22741 attatatcaa aaaggtagaa taaaatcatg gaaatgtggt ataataaagc caagtaaaga
    22801 gaaacgagaa gcacatgtat attgaaatgg tagatgaaac tggtcaagtt tcaaaagaaa
    22861 tgttgcaaca aacccaagaa attttggaat ttgcagccca aaaattagga aaagaagaca
    22921 aggagatggc agtcactttt gtgaccaatg agcgtagtca tgaacttaat ctggagtacc
    22981 gtgacaccga ccgtccgaca gatgtcatca gccttgagta taaaccagaa ttggaaattg
    23041 cctttgacga agaggatttg cttgaaaatc tagaattggc agagatgatg tctgagtttg
    23101 atgcctatat tggggaattg ttcatctcta tcgataaggc tcatgagcag gctgaagaat
    23161 atggtcacag ctttgagcgt gagatgggct tcttggcagt acacggcttt ttacatatta
    23221 acggctatga tcactacact ccggaagaag aagcggagat gttcggttta caagaagaaa
    23281 ttttgacagc ctatggactc acaagacaat aaacgaaaat ggaaaaatcg tgacttgata
    23341 tccagtttag aatttgcttt gacaggtatt tttactgcta tcaaggaaga acgcaatatg
    23401 cgaaaacacg cagtgacggc tctagtggtc atccttgcag gttttgtttt tcaggtgtca
    23461 cgaatcgaat ggctctttct cctattgagt attttcttgg tagtagcctt tgagattatc
    23521 aactctgcta ttgaaaatgt ggtggatttg gccagtcact atcacttttc catgctggct
    23581 aaaaatgcca aggatatggc ggccggcgcg gtattagtgg tttctctttt cgcagcctta
    23641 acaggcgcat tgatttttct cccacgaatc tgggatttat tattttaaac agtaagagga
    23701 aattatgact tttaaatcag gctttgtagc cattttagga cgtcccaatg ttgggaagtc
    23761 aaccttttta aatcacgtta tggggcaaaa gattgccatc atgagtgaca aggcgcagac
    23821 aacgcgcaat aaaatcatgg gaatttacac gactgataag gagcaaattg tctttatcga
    23881 cacaccaggg attcacaagc ctaaaacagc tctcggagat ttcatggttg agtctgccta
    23941 cagtaccctt cgcgaagtgg acaccgttct tttcatggtg cctgctgatg aagcgcgtgg
    24001 taagggggac gatatgatta tcgagcgtct caaggctgcc aaggttcctg tgattttggt
    24061 ggtgaataaa atcgataagg tccatccaga ccagctcttg tctcagattg atgacttccg
    24121 taatcaaatg gactttaagg aaattgttcc aatctcagcc cttcagggaa ataacgtgtc
    24181 tcgtctagtg gatattttga gtgaaaatct ggatgaaggt ttccaatatt tcccgtctga
    24241 tcaaatcaca gaccatccag aacgtttctt ggtttcagaa atgattcgcg agaaagtctt
    24301 gcacctaact cgtgaagaga ttccgcattc tgtagcagta gttgttgact ctatgaaacg
    24361 agacgaagag acagacaagg ttcacatccg tgcaaccatc atggtcgagc gcgatagcca
    24421 aaaagggatt atcatcggta aaggtggcgc tatgcttaag aaaatcggta gcatggcccg
    24481 tcgtgatatc gaactcatgc taggagacaa ggtcttccta gaaacctggg tcaaggtcaa
    24541 gaaaaactgg cgcgataaaa agctagattt ggctgacttt ggctataatg aaagagaata
    24601 ctaagtagag gtaggctcat gcctgcttct tgtttttaca gaaggaggac ttatgcctga
    24661 attacctgag gttgaaaccg tttgtcgtgg cttagaaaaa ttgattatag gaaagaagat
    24721 ttcgagtata gaaattcgct accccaagat gattaagacg gatttggaag agtttcaaag
    24781 ggaattgcct agtcagatta tcgagtcaat gggacgtcgt ggaaaatatt tgctttttta
    24841 tctgacagac aaggtcttga tttcccattt gcggatggag ggcaagtatt tttactatcc
    24901 agaccaagga cctgaacgca agcatgccca tgttttcttt cattttgaag atggtggcac
    24961 gcttgtttat gaggatgttc gcaagtttgg aaccatggaa ctcttggtgc ctgacctttt
    25021 agacgcctac tttatttcta aaaaattagg tcctgaacca agcgaacaag actttgattt
    25081 acaggtcttt caagctgccc ttgccaagtc caaaaagcct atcaaatccc atctcctaga
    25141 ccagaccttg gtagctggac ttggcaatat ctatgtggat gaggttctct ggcgagctca
    25201 ggttcatcca gctagacctt cccagacttt gacagcagaa gaagcgactg ccattcatga
    25261 ccagaccgtt gctgttttgg gccaggctgt tgaaaaaggc ggttccacca ttcggactta
    25321 taccaatgcc tttggggaag atggaagcat gcaggacttt catcaggtct atgataagac
    25381 tggtcaagaa tgtgtacgct gtggtaccat cattgagaaa attcaactag gcggacgtgg
    25441 aacccacttt tgtccaaact gtcaaaggag ggactgatgg gaaaaatcat cggaatcact
    25501 gggggaattg cctcaggtaa gtcaactgtg acaaattttc taagacagca aggctttcaa
    25561 gcagtggatg ccgacgcagt cgtccaccaa ctacagaaac ctggtggtcg tctgtttgag
    25621 gctctagtac agcactttgg gcaagaaatc attcttgaaa acggagaact caatcgccct
    25681 ctcctagcta gtctcatctt ttcaaatcct gaagagcaaa aatggtctaa tcaaattcaa
    25741 ggggagatta tccgtgagga actggctact ttgagagaac agttggctca gacagaagag
    25801 attttcttca tggatattcc cctacttttt gagcaggact acagcgattg gtttgctgag
    25861 acttggttgg tctatgtgga ccgagatgcc caagtagaac gcttaatgaa aagggaccag
    25921 ttgtccaaag atgaagctga gtctcgtctg gcagcccagt ggcctttaga aaaaaagaaa
    25981 gatttggcca gccaggttct tgataataat ggcaatcaga accagcttct taatcaagtg
    26041 catatccttc ttgagggagg taggcaagat gacagagatt aactggaagg ataatctgcg
    26101 tattgcctgg tttggtaatt ttctgacagg agccagtatt tctttggttg taccttttat
    26161 gcccatcttc gtggaaaatc taggtgtagg gagtcagcaa gtcgcttttt atgcaggctt
    26221 agcaatttct gtctctgcta tttccgcggc gctcttttct cctatttggg gtattcttgc
    26281 tgacaaatac ggccgaaaac ccatgatgat tcgggcaggt cttgctatga ctatcactat
    26341 gggaggcttg gcctttgtcc caaatatcta ttggttaatc tttcttcgtt tactaaacgg
    26401 tgtatttgca ggttttgttc ctaatgcaac ggcactgata gccagtcagg ttccaaagga
    26461 gaaatcaggc tctgccttag gtactttgtc tacaggcgta gttgcaggta ctctaactgg
    26521 tccctttatt ggtggcttta tcgcagaatt atttggcatt cgtacagttt tcttactggt
    26581 tggtagtttt ctatttttag ctgctatttt gactatttgc tttatcaagg aagattttca
    26641 accagtagcc aaggaaaagg ctattccaac aaaggaatta tttacctcgg ttaaatatcc
    26701 ctatcttttg ctcaatctct ttttaaccag ttttgtcatc caattttcag ctcaatcgat
    26761 cggccctatt ttggctcttt atgtacgcga cttagggcag acagagaatc ttctttttgt
    26821 ctctggtttg attgtgtcca gtatgggctt ttccagtatg atgagtgcag gagtcatggg
    26881 caagctaggt gacaaggtgg gcaatcatcg tctcttggtt gtcgcccagt tttattcagt
    26941 catcatctat ctcctctgtg ccaatgcctc tagccccctt caactaggac tctatcgttt
    27001 cctctttggc ttgggaaccg gtgccttgat tcccggggtt aatgccctac tcagcaaaat
    27061 gactcccaaa gccggcattt cgagggtctt tgccttcaat caggtattct tttatctggg
    27121 aggtgttgtt ggtcccatgg caggttctgc agtagcaggt caatttggct accatgctgt
    27181 cttttatgcg acaagccttt gtgttgcctt tagttgtctc tttaacctga ttcaatttcg
    27241 aacattatta aaagtaaagg aaatctagtg cgagtaaaaa ttaatctcaa atgctcctct
    27301 tgtgacagta tcaattacct aaccagtaaa aattcaaaaa cccatccaga caagattgag
    27361 gttttaaagt attgtcccaa ggaaagaaaa gtaaccctac atcttgaatc taagtagatt
    27421 ttatggtaaa ataataggga ttttaaggag tttgatatgt ataacctatt attaaccatt
    27481 ttattagtat tatctgttgt gattgtgatt gcaattttca tgcaaccaac caaaaaccaa
    27541 tccagcaatg tatttgatgc cagttcaggt gatttgtttg aacgcagtaa agctcgcggt
    27601 tttgaagctg taatgcagcg tttgacaggg attttagtct ttttctggct agccattgcc
    27661 ttagcattga cggtattatc aagtagataa gaaaataatg ggcaggacta ggtctttgcc
    27721 tctttttatt tttaaaggat gtttgagaag gttttacagt aaaagaaaat taaaaaatct
    27781 agaaagaaaa tatgaaagat agaataaaag aatatttaca agacaaggga aaggtgactg
    27841 ttaatgattt ggctcaggct ttgggaaaag acagttccaa ggattttcgt gagttgatta
    27901 aaaccttgtc cttaatggaa agaaagcacc aaattcgttt tgaagaagat ggtagtctga
    27961 cattagaaat taagaaaaaa catgagatta ccctcaaggg gatttttcat gcccataaaa
    28021 atggctttgg ctttgttagt ctggaaggcg aggaggacga cctttttgta gggaaaaatg
    28081 atgtcaacta tgctattgat ggtgataccg tcgaggtagt gattaagaaa gtcgctgacc
    28141 gcaataaggg aacagcagca gaagccaaaa ttattgatat cctagaacac agtttgacaa
    28201 cagttgtcgg gcaaatcgtt ctggatcagg aaaaacctaa gtatgctggc tatattcgtt
    28261 caaaaaatca gaaaatcagt caaccgattt atgttaagaa accagcccta aaattagaag
    28321 gaacagaagt tctcaaagtc tttatcgata aatacccaag caagaaacat gatttctttg
    28381 tcgcgagtgt tctcgatgta gtgggacact caacggatgt cggaattgat gttcttgagg
    28441 tcttggaatc aatggacatt gtatccgagt ttccagaagc tgttgttaag gaagcagaaa
    28501 gtgtgcctga tgctccgtct caaaaggata tggaaggtcg tctggatcta agagatgaaa
    28561 ttacctttac cattgacggt gcggatgcca aggacttgga cgatgcagtg catatcaagg
    28621 ctctgaaaaa tggcaatctg gagcttgggg ttcacatcgc agatgtttct tattatgtga
    28681 ccgaggggtc tgcccttgac aaggaagccc ttaaccgtgc gacttctgtt tacgtgacag
    28741 accgagtggt gccaatgctt ccagaacgac tatcaaatgg catctgctct ctcaatcccc
    28801 aagttgaccg cctgacccag tctgctatta tggagattga taaacatggt cgtgtggtca
    28861 actataccat tacacaaaca gttatcaaga ccagttttcg tatgacctat agcgatgtca
    28921 atgatatcct agctggcgat gaagaaaaga gaaaagaata tcataaaatt gtatcaagta
    28981 tcgaactcat ggccaagctt catgaaactt tagaaaacat gcgtgtgaaa cgtggagctc
    29041 tcaattttga taccaatgaa gcgaagattt tagtggataa acaaggtaag cctgttgata
    29101 tcgttcttcg gcagcgtggt attgccgagc ggatgattga gtcttttatg ttgatggcta
    29161 atgaaacagt tgccgaacat ttcagcaagt tggatttgcc ttttatctat cgaattcacg
    29221 aggagcctaa ggctgaaaag gttcagaagt ttattgatta tgcttcgagt tttggcttgt
    29281 gcatttatgg aactgccagt gagattagtc aggaggcact tcaagacatc atgcgtgctg
    29341 ttgagggaga accttatgca gatgtattgt ccatgatgct tcttcgctct atgcagcagg
    29401 ctcgttattc ggagcacaat cacggccact atggactagc tgctgactat tatactcact
    29461 ttaccagtcc aattcgtcgt tatccagacc ttcttgttca ccgtatgatt cgggattacg
    29521 gccgttctaa ggaaatagca gagcattttg aacaagtgat tccagagatt gcgacccagt
    29581 cttccaactg tgaacgtcgt gccatagaag ctgagcgtga agtcgaagcc atgaaaaagg
    29641 ctgagtatat ggaagaatac gtgggtgaag agtatgatgc agttgtatca agtattgtca
    29701 aattcggtct ctttgtcgaa ttgccaaaca cagttgaagg cttgattcac atcactaatc
    29761 tacctgaatt ttatcatttc aatgagcgtg atttgactct tcgtggagaa aaatcaggta
    29821 tcactttccg agtgggtcag cagatccgta tccgtgttga aagagcggat aaaatgactg
    29881 gagagattga tttttcattc gtacctagtg agtttgatgt gattgaaaaa ggcttgaaac
    29941 agtctagtca tagtggcaga gggcgtggtt caaatcgtcg ttcggataag aaggaagaca
    30001 agagaaaatc aggacgctca aatgataagc gtaagcattc acaaaaagac aagaagaaaa
    30061 aaggaaagaa acctttttac aaggaagtag ctaagaaagg agccaagcat ggcaaagggc
    30121 gagggaaagg tcgtcgcaca aaataaaaag gcacgccacg actatacaat cgtagatacg
    30181 ctagaggcag ggatggtcct gactggaact gaaatcaaga gtgtacgagc tgctcgaatt
    30241 aatctcaagg atggctttgc tcaagtgaaa aatggagaag tttggctgag caatgttcat
    30301 atcgcgcctt acgaagaggg caatatctgg aaccaggaac cagaacgtcg tcgtaaactc
    30361 ctgctccata aaaagcaaat tcaaaaattg gaacaagaga ccaaagggac aggaatgacc
    30421 ttagttcccc ttaaggtcta tataaaagat ggctacgcta agcttctttt aggacttgcc
    30481 aaagggaagc atgactatga caaacgggag tctatcaaac gtcgtgagca aaatcgagat
    30541 atcgcgcgtg tgatgaaagc tgttaatcag cgataaaaag aggaattgaa aatggaaaaa
    30601 ttagttgcct ataaacgcat gcctttgtgg aataaacaaa caatgcctga agctgttcag
    30661 caaaagcaca atacaaaagt tgggacttgg gggaaaatta ctgtcttgaa gggagctctc
    30721 aagtttattg aattgacaga agaaggggaa gttctagctg aacacctctt tgaagcaggg
    30781 gcagacaatc caatggccca acctcaagcc tggcaccgag tggaagctgc cacagatgat
    30841 gtggaatggt acttggaatt ttattgtaaa cctgaggatt attttgctaa aaaatacaat
    30901 accaatcctg ttcattcaga ggtcctagag gccatgcaga cagtgaaaca agggaaagct
    30961 ttggatttgg gttgtggtca ggggcgtaat tctctttttc tagcccagca agattttgat
    31021 gtgacggctg tagatcaaaa tggactagct cttgaaatct tgcaaagcat tgtggagcag
    31081 gaagatttgg acatgcctgt tggcctttac gatatcaatt cagctagcat tgaacaagaa
    31141 tatgatttta tcgtttcaac agttgttctc atgtttctac aagcggaccg cattccagct
    31201 attattcaaa atatgcagga gaaaaccagt gttggtggtt acaaccttat cgtttgtgcc
    31261 atggacacgg aggattatcc ttgctcggtt aacttcccat tcacctttaa agaaggagaa
    31321 ctggcagact attacaagga ttgggaattg gttaagtaca atgaaaatcc aggccatttg
    31381 caccgtcgcg atgagaatgg caatcgtatt caactacgct ttgcgacctt actagctaag
    31441 aaaatcaagt aaacatacat gaagattagg aattttcctg atcttttttc ttttttacga
    31501 atgatataga aaaggaggga attcatgttt gttgcgagag atgctagggg agaattggta
    31561 aatgtgttag aggataaact tgagaagcaa gcatacacct gcccagcttg tggaggccag
    31621 atccatttgc gtcaaggacc aagtgtacgg acgcattttg cccataaatc cttaaaagac
    31681 tgtgattttt tctttgaaaa tgaaagtcca gaacacctgg ccaataagga atccctctat
    31741 cactggttga aaaaagagac aaaggttcaa ttagagtacc cgctttcaga acttaaacag
    31801 attgcggatg tatttgtaaa tggcaatcta gctctagaag ttcagtgtag tcccttgcct
    31861 cagaaagtcc ttaaagagcg aagtgagggc tatcgtagtc agggttacca agtactgtgg
    31921 ttgctgggtc aaaaactgtg gctcaaggag cgtttgactc gtctacagca aggttttctt
    31981 tatttcagtc aaaacatggg cttttatgtt tgggaattag acaaggaaaa acaagtttta
    32041 agactcaaat acctgattta ccaggatctc cgcggtaaac tccattatca aatcaaggaa
    32101 ttttcctatg gtcaaggtag tttattggaa atattgcgtc ttccctataa gaaacaaaaa
    32161 atatctcatt ttacagtttc tgaggacaag gacatctgtc gctatatccg gcaacaactt
    32221 tattatcaaa atctcttttg gatgaaagaa caagcagaag cctatcaaaa gggagaaaat
    32281 atcctgactt atggactgaa agaatggtat ccacaaattc gaccaatagt gggcaaattt
    32341 ttccagattg aacaagactt gactagctat tatcagcact tttataccta ttaccaaaaa
    32401 aatcctcaaa atgattggca aaagctttat ccaccagcct tttatcagca atatttcttg
    32461 aaaaatatgg tagaatagaa aggatggagg aatctaatgg tattacaaag aaatgaaata
    32521 aatgaaaaag atacatggga tctatcaacg atctacccaa ctgaccaggc ttgggaagaa
    32581 gccttaaaag atttaacaga acaattggag acagtagccc agtatgaagg ccatctcttg
    32641 gatagtgcgg ataacctact agaaatcact gaattttctc ttgaaatgga acgccagatg
    32701 gagaagcttt acgtttatgc tcatatgaag aatgaccagg atacacgtga agctaagtat
    32761 caagagtact atgccaaggc catgacactc tacagccagt tagaccaagc cttttcattc
    32821 tatgagcctg aatttatgga gattagcgaa aagcagtatg ctgacttttt agaagctcaa
    32881 ccaaagctgc aggtttatca acactatttt gacaagctct tgcaaggcaa ggatcacgtt
    32941 ctctcacaac gtgaagaaga attattggct ggagctggag aaatctttgg ttcagcaagt
    33001 gaaaccttcg ctatcttgga caatgcggat attgtgttcc cttatgtcct agacgatgat
    33061 ggtaaagaag ttcagctatc tcatgggatt tacacacgtt tgatggagtc taaaaaacgt
    33121 gaggttcgcc gtggtgccta tcaagctctt tatgcgactt acgaacaatt ccaacacacc
    33181 tatgccaaaa ccttgcaaac caatgttaag gtgcaaaatt accgtgctaa agttcgtaac
    33241 tacaagagtg ctcgtcatgc agccctcgca gcgaattttg ttccagaaag tgtttatgac
    33301 aatttggtag cagcagttcg caagcatttg ccactcttac atcgctatct tgagcttcgt
    33361 tcaaaaatct tggggatttc agatctcaag atgtacgatg tctacacacc gctttcatct
    33421 gttgaataca gttttaccta ccaagaagcc ttgaaaaaag cagaagatgc tttggcagtc
    33481 ttgggtgagg attacttgag ccgtgtcaaa cgtgccttca gcgagcgttg gattgatgtt
    33541 tacgaaaatc aaggcaagcg ttcaggtgcc tactctggtg gttcttacga taccaatgcc
    33601 tttatgcttc tcaactggca ggacaatctg gacaatctct ttactcttgt tcatgaaaca
    33661 ggtcacagta tgcattcaag ctatactcgt gaaactcagc cttatgttta cggagattac
    33721 tctatctttt tggctgagat tgcctcaact accaatgaaa atatcttgac ggagaaatta
    33781 ttggaagaag tggaagacga cgcaacacgc tttgctattc tcaataactt cctagatggt
    33841 ttccgtggaa cagttttccg ccaaactcaa tttgctgagt ttgaacacgc cattcaccaa
    33901 gcagatcaaa atggggaggt cttgacaagc gatttcctaa ataaactcta cgtagacttg
    33961 aaccaagagt attatggttt gagtaaggaa gacaatcctg aaatccaata cgagtgggct
    34021 cgcattccac acttctacta taactactat gtatatcaat attcaactgg atttgcggcc
    34081 gcctcagcct tggctgaaaa aattgtccat ggtagtcaag aagaccgtga ccgctatatc
    34141 gactacctca aggcaggtaa gtcggactat ccacttaatg tcatgagaaa agctggtgtt
    34201 gatatggaga aggaagacta cctcaacgat gcctttgcag tctttgaacg ccgtttaaat
    34261 gagtttgaag cccttgttga aaaattagga ttggcataaa atggttgaat cgtatagtaa
    34321 gaatgctaac cataacatgc gtcgtcctgt cgtcaaagaa gaaattgtag acttgatgcg
    34381 tcagcgtcaa aagcaggtca caggttcctt gaaagaattg gaagactttg cccgcaagga
    34441 aaatattcct attattcccc atgaaacggt tgcttatttc cgttttctta tggaaaccat
    34501 gcagcctaaa aatattctgg aaattgggac ggctatcggt ttttcagctc tcttgatggc
    34561 tgaacatgcg ccaaatgcta agattacaac tattgatcgt aatccagaaa tgattggttt
    34621 tgccaaggaa aattttgccc agtttgacag tcgcaagcaa atcactctcc tagagggaga
    34681 tgcggtggat gtcttatcta cactgacaga gtcttatgat ttcgtcttta tggattctgc
    34741 caagtctaaa tacatcgtct ttctgccaga aattctcaaa catttggaag ttggtggtgt
    34801 ggttgtcttg gatgatattt tccaaggcgg tgatgttgcc aaggacatta tggaagtccg
    34861 tcgaggtcag cgaaccatct atcgaggcct tcaaagacta tttgacgcaa ccttagacaa
    34921 ttcagaactc accgcaacat tagtgccttt aggagatggt attctcatgc ttcgtaaaaa
    34981 tgtagcagat gttcaattgc ctgacagcga atgattttca gaaaaattta agaaaaaata
    35041 gtaaaataga tagagtaaca cttatctcaa aggagtagac atgaagaaaa aattattggc
    35101 aggtgccatc acactattat cagtagcaac tttagcagct tgttcgaaag ggtcagaagg
    35161 agcagacctt atcagcatga aaggggatgt catcacagaa catcaatttt atgagcaagt
    35221 gaaaaacaac ccttcagccc aacaagtctt gttaaatatg accatccaaa aagtttttga
    35281 aaaacaatat ggctcagagc ttgatgataa agaggttgat gatactattg ccgaagaaaa
    35341 aaaacaatat ggcgaaaact accaacgtgt cttgtcacaa gcaggtatga ctcttgaaac
    35401 acgtaaagct caaattcgta caagtaaatt agttgagttg gcagttaaga aggtagcaga
    35461 agctgaattg acagatgaag cctataagaa agcctttgat gagtacactc cagatgtaac
    35521 ggctcaaatc atccgtctta ataatgaaga taaggccaaa gaagttctcg aaaaagccaa
    35581 ggcagaaggt gctgattttg ctcaattagc caaagataat tcaactgatg aaaaaacaaa
    35641 agaaaatggt ggagaaatta cctttgattc tgcttcaaca gaagtacctg agcaagtcaa
    35701 aaaagccgct ttcgctttag atgtggatgg tgtttctgat gtgattacag caactggcac
    35761 acaagcctac agtagccaat attacattgt aaaactcact aagaaaacag aaaaatcatc
    35821 taatattgat gactacaaag aaaaattaaa aactgttatc ttgactcaaa aacaaaatga
    35881 ttcaacattt gttcaaagca ttatcggaaa agaattgcaa gcagccaata tcaaggttaa
    35941 ggaccaagcc ttccaaaata tctttaccca atatatcggt ggtggagatt caagctcaag
    36001 cagtagtaca tcaaacgaat agtccaaatc aatgaatcag ggaaaaaact cgacttcagg
    36061 aaaaaatgaa gcaaacattc ccacaataaa acgcgtagta caaggtttgt actgaccccc
    36121 aaaagttaga caaataattt atccgaagga tttagttctg tattgcacag ggctaagtcc
    36181 ttttagtttt accttaattc tcttgttgtt gtaataatca atatagtcta taatggcttg
    36241 ttccaattga ttaagtgatt taaatgtttt ctcatagcca taaaacattt cggattttaa
    36301 aatgccaaag aaagattcca tcctaccgtt gtcttggctg tttcctttgc gtgacataga
    36361 tgcttgaatt cccttactct ctaggaagcg atgataagaa tcgtgttggt attgccagcc
    36421 ttggtcacta tggagaatcg tattctcgta gtgcttctct ttgaatgcct gttccaacat
    36481 taacgatcaa tcaatttaat catgtaccta atattagaat tgtttatccc aaatttattt
    36541 gaaagcttct ctaagctata tccttgtttt ctaagttcat agatctgaac tttatcatca
    36601 taagttaatt tcataataaa aacaccccaa aagttagatt ttttttgtct aacttttggg
    36661 gtgtagttca tgtacacctg atatgatgca ttttataatt ttaaagactt tttgactagc
    36721 ctcatttttt taacttgata ctcagtgaaa agcaaagatt aaactaggaa gctagctgta
    36781 ggctgctcaa agaacagctt tgaggttgca gataaaactt gtgaggtaac caacatatat
    36841 aatgtgaagc tgacgtggtt tgaatagatt ttagaagggt atgagtctgg aagttttaat
    36901 ggataatgca agattccata gaatgggtaa gctagagttc ttatgtgaag agtttgggca
    36961 taaactttta ccttttcctc cctactcatc ttagtataga aaagtgaatc taaaatagta
    37021 cataactgct tctaaaacat tcttataaat tgatttaaat tctcaaatca tattattcag
    37081 ttcttatttc attttgctct acaatcctgt tgagaagaca cgtgttcata tcaaaaaggt
    37141 attggcaagt tgcaatacct ttttacgagg ctctgttgtc ttatttttgt ttcaactgac
    37201 tatatctcct atggttctag ttcagaaggc taggctataa ttatgattga taagaagtat
    37261 cattccaagt attgagagtg aatgtttcaa aatcatgggt ttctataatg gtcaggctgg
    37321 catttgctag accgccatct ttacgaagaa gtggttcttt atagcctagg agagtacgaa
    37381 gactggcagt aagattggcg ccgtgtccga caattagaat acgctcagct ggactatctt
    37441 ttaatgattt gataaattgg atggtccgct gagttgtact atagagggat tcggctccga
    37501 acattcgagt gtcaaattga gcaagatttg aacgaaaagc ctggatttgt tgcgggtaaa
    37561 tagcttccag ggttgcaatt ttcaaacctt ctaacttccc aagttgccat tcacggagat
    37621 taggaacgat ttctaaagaa cagggggtat ggagttgact ttggataatc tcagcagatt
    37681 tgaccgctcg aggtaaatca cttgaataaa tctgatcaaa aggaatttcc ttgagatact
    37741 gaccaagtcg ttttagggtt tcaatggatt caggaagaag aggagaatca ccactagcac
    37801 cttgaaaacg accttcttgg ttccagaggg tacgaccgtg gcggacaaag tagagtttca
    37861 ttacttgatg tcctccaaaa tatctacaaa gtctgccttt acaaagctag ccaagtcttg
    37921 tggcgcgacg ataatgctgt gtccgacttc gcctgcagag acaatcattt gatccaaatc
    37981 tagagcaatt ttatcgataa aaatgggata attgtgtttc tgacgaattc cgacaggatt
    38041 attggctcca tgaatgtaac cagttgtttt ttctaagtac ttttgtggaa tcatgctcac
    38101 ttttttattg ccagaaattt tagctagttt cttttcagac aagtgctgag tgatagggac
    38161 aattccgata atcggtccgg tcttgtctcc caaaagcgcc aaggttttga aaatctgatc
    38221 tcgttcataa ccttgaggaa gctctccttc tagggcattg atttgaatcc cctgatgagg
    38281 gatagctgct ttagatagga tttgttctac caatgttttt ttgattttaa ctttttttgc
    38341 cattatttat atttatcctc caattgactc atccaaatac caagccagat tcccagcgca
    38401 aagaagaagg cgatgatgac ataaccgaca agtgaaagtc ctgtgtattg gatactttca
    38461 gcgtttcctg catttggaat taagatcaaa agggtacttg ataggacgat accgatgatg
    38521 aaatgataga cgcgtgagtg gtagttgttt aaggcataat ccatcaattt tgaaaaaacg
    38581 atgagagttg cacctgcacc aattccaatc ggaaagaagg ttcccaagag atcaaaagtt
    38641 ttaaaaccag tcaacatagg agcatagagt cccaaaatca aaagtaaatt cgatgggctg
    38701 aggccaggaa ccaagacgcc aagggccaat agtgcgcctg ctaggacgaa gttaagaaag
    38761 ctggcgctta aggttccaac gacaaaattt aaggcataga gtcctaatcc agaaatgata
    38821 aaggttgtcc ataaccaagc taaatcaatc ttgtctcggt cagattctcg agttgattct
    38881 ttgaggaggc taggaactgt accgataata gctcccgcaa agctccataa tacaaagacc
    38941 tgataatttt caagcaggta ttcaatcggg taggaaaata agccgattcc cagaagcata
    39001 ccgatggcaa ctggaataaa gtacaaaaca ttttctttaa ggtctttaaa gggatgggcc
    39061 agaaagccaa tcattcgttc atagattcct aagattgctg ctagaacccc tccggaaatt
    39121 cccggtagga taaatccaag agcaattaca atccctttaa taacgcgtgc taaccatgag
    39181 agcatatatt tcctccaact atttctattt caaaaaatcc ttactatatt gtatcacaat
    39241 cagacacaaa aagaaaaagc aaatgataaa caaatgcttt taaggtttta aaaaaagctt
    39301 tcgaaaggtt tcttttttat tttttaaggg agagataacg ttgatatcta aatcgtggtc
    39361 aaagccggca atttttcctt tagatgtgta ttggtgaata tcataatcta aatcagtttt
    39421 aggactgctc tccaaaaatc ctgagtctga gccgtaggac ggaatccaaa cagaggtaaa
    39481 cttgcctgta tcaatactgt gttcttccat gaagtagaca ccaacgtaga tgccgatgtt
    39541 tttagcacct agtgatgcta gttttgctcg aaagttttcg acaccttcgt tcatattaga
    39601 catggttttg tcttccacgt caagccaata gtaactaggg ctgtaaggag aggcagcatt
    39661 gtagaaaact tcggcagcct tttccatttc ttggacactt tttccagcta cataagcgta
    39721 gacagcaact gggacattcc gcttttgaag ttcagtgata tgactcttat aggccttgtc
    39781 tattccattg ataaatgaag catcattttc ttttgtcgtt tgagcaccac tgtgaacacg
    39841 aacaatagca cctgaaatat tttgtgagag ggcgtcgtag ttgatttcct caggacgctg
    39901 ccagccagag aggtcaataa tcggtttgtc taagtgtttc aaagcctgtg cttcaatctg
    39961 tgctatattg gattttgttt taaacgattg gctgtcatta agtgggcgat tgatgattaa
    40021 aatgaacatc ataatcccaa aaaaactaaa taaaataagt ggatgaattt gttttctcat
    40081 atcttataat tctaccctaa aaatcaaaaa aaatcaaaaa aatgggttaa ggaagagact
    40141 ttagagcatt ttttcattca agagtgcgga atgatttgaa atatggtata ataaaaggga
    40201 atttctacag aaaagagaag attatgtcaa attttgccat tattttagca gcgggtaaag
    40261 ggactcgcat gaaatctgat ttgccaaaag ttttgcacaa ggttgcgggt atttctatgt
    40321 tggaacatgt tttccgtagt gtgggagcta tccaacctga aaagacagta acagttgtag
    40381 gacacaaggc agaattggtt gaggaggtct tggctggaca gacagaattt gtgactcaat
    40441 ctgaacagtt gggaactggt catgcagtta tgatgacaga gcctatctta gaaggtttgt
    40501 caggacacac cttggtcatt gcaggagata ctcctttaat cactggtgaa agcttgaaaa
    40561 acttgattga tttccatatc aatcataaaa atgtggccac tatcttgact gctgaaacgg
    40621 ataatccttt tggctatgga cgaattgttc gtaatgacaa tgctgaggtt cttcgtattg
    40681 ttgagcagaa ggatgctaca gattttgaaa agcaaatcaa ggaaatcaac actggaacat
    40741 acgtctttga caacgagcgt ttgtttgagg ctttgaaaaa tatcaatacc aataacgctc
    40801 aaggcgaata ctatattaca gacgtcattg gtattttccg tgaaactggt gaaaaagttg
    40861 gcgcttatac tttgaaagat tttgatgaaa gtcttggggt aaatgaccgt gtggcgcttg
    40921 cgacagctga gtcagttatg cgtcgtcgca tcaatcataa acacatggtc aatggtgtta
    40981 gctttgtcaa tccagaagca acttatatcg atattgatgt tgagattgct ccggaagttc
    41041 aaatcgaagc caatgttacc ttgaaagggc aaacgaaaat tggtgctgag actgttttga
    41101 caaacggtac ttatgtagtg gacagcacta tcggagcagg agcggtcatt accaattcta
    41161 tgattgagga aagtagtgtt gcagacggtg tgacagtcgg tccttatgct cacattcgtc
    41221 caaattcaag tctgggtgcc caagttcata ttggtaactt tgttgaggtg aaaggatctt
    41281 caatcggtga gaataccaag gctggtcatt tgacttatat cggaaactgt gaagtgggaa
    41341 gcaacgttaa tttcggtgct ggaactatta cagtcaacta tgacggcaaa aacaaataca
    41401 agacagtcat tggagacaat gtctttgttg gttcaaattc aaccattatt gcaccagtag
    41461 aacttggtga caattccctc gttggtgctg gttcaactat tactaaagac gtgccagcag
    41521 atgctattgc tattggtcgc ggtcgtcaga tcaataaaga cgaatatgca acacgtcttc
    41581 ctcatcatcc taagaaccag taggagccta tcatggagtt tgaagaaaaa acgcttagcc
    41641 gaaaagaaat ctatcaagga ccaatattta aactggtcca agatcaggtt gaattaccag
    41701 aaggcaaggg aactgcccga cgggatttga ttttccacaa tggggctgtc tgtgttttag
    41761 cagtaacgga tgaacaaaaa cttatcttgg tcaagcagta ccgcaaagct atcgaggctg
    41821 tctcttacga aattccagcc ggaaaattgg aagtaggaga aaacacagcc cctgtggcag
    41881 ctgcccttcg tgaattagag gaagaaacag cctatacagg gaaattagaa ctcttgtacg
    41941 atttttattc agctattggc ttttgtaatg agaagttaaa actatattta gcaagcgatt
    42001 tgacaaaagt ggaaaatccg cgtccgcagg atgaggatga aaccttggaa gtccttgaag
    42061 tgagcttaga agaagcgaaa gaattaatcc aatcaggtca tatctgtgat gccaagacaa
    42121 ttatggctgt tcagtattgg gagttgcaga aaaaatagag gaggtcagta tgggtaaatc
    42181 tttattaacg gatgaaatga ttgaaagagc taatagaggc gaaaaaattt caggtcctcc
    42241 tttgctagat gataatgagg aaactaagat tttaccaacc tcttcttccc gttttggtta
    42301 tgccaatcct aaggatcatg gttttagcca ggaaaccttg aagattcagg tcgaaccatc
    42361 tattcataaa agccgtcgca ttgaaaatac caagagaaat gtcttcaatt ctaagttgaa
    42421 taaaatctta ttcgcggtca tctttctctt gattttgctt gttttagcaa tgaaactttt
    42481 gtaatagaaa aggaattgaa atgaaaatag gaattattgc tgctatgcca gaagaactgg
    42541 cttatctggt ccagcattta gacaatgccc aggagcaagt tgttttgggg aatacctatc
    42601 atacaggaac cattgcttct catgaagtcg ttcttgtaga aagtggaatt ggtaaggtca
    42661 tgtctgctat gagtgtggcg attttggctg atcatttcca ggtggatgcc cttattaata
    42721 cgggttcagc tgggacagta gcagaaggta tcgctgttgg ggatgtcgtg attgctgaca
    42781 aattagccta tcatgacgtg gatgtcacag cttttggcta tgcttatgga caaatggcgc
    42841 aacaaccgct ttatttcgaa tcagacaaaa cctttgttgc tcaaatccaa gagagtttat
    42901 ctcaattgga ccaaaactgg catcttggtt tgattgctac aggagatagt tttgttgcag
    42961 gaaatgacaa gatagaagcg attaagtccc atttcccaga agttttagcc gtggagatgg
    43021 agggggcagc tattgctcaa gcagcgcatg ccctcaatct cccagtctta gtcatcagag
    43081 ctatgagtga caatgccaac catgaagcaa acatcttttt tgatgagttt attatcgaag
    43141 ctggacgtcg ctctgcccaa gtcttgttga cctttttgaa ggctttagat taagcggaaa
    43201 tttgacagtt tttctagctt atgataagat ttaagtaaag aaaagctaga aaacgtttca
    43261 gaggatatta tgagtattga aatgaccgtc agtgagattg cagaggtctt aggattatct
    43321 cgccaagcaa tcaataaccg tgtcaaagaa ttaccagaag aagacacaga taaaaatgac
    43381 aaaggggtaa cagttgttac cagaagtggc ttgattaagc tagaagaaat ctataaaaaa
    43441 acgatttttg aagatgagcc tgtcagtgaa gatgtcaaac aacgtgaact gatggagatt
    43501 ctagtggatg agaagaatgc agaaattctt cgtctttatg aacaattaaa agccaaggat
    43561 cgtcagttat cagaaaaaga cgagcagatg cgtatcaaag accgtcagat tgctgagaaa
    43621 gacaaacaat tagatcagca acaacaattg acccttcaag ccatgaagga tcaagaaaat
    43681 cttaagctag agctggacca agcaaaagaa gaagtccaat ccactaagaa aggctttttt
    43741 gctcgtttat ttggaggata atcaaggagc tgtttaggtt aaatgctaac ctgatggctt
    43801 cttttgtttg tgaatagtat agttgattag aacagagaca gtagaggaga ggtacagaat
    43861 ggaacgatta gaagattaca ttgcttttga tttagaattt aatcagcacg aaggacaaac
    43921 acacttgatt caagtatcgg cagtgcgttt tagagatggt cgggaaatcg atgcctatga
    43981 ttcctatgtt cataccagcg tccctctaaa aagctttatc aatggtttga ccgggattac
    44041 agctgagacc ttaaaagatg ctcctccagt tgagaaagtc ttagaagaat tccaagagtt
    44101 tgtgggttct ttgctgatga taggctacaa tgctgctaaa agtgatttac ctattttagc
    44161 agagcatggt ttagactata gccaacagta caaggtggat ttgtatgatg aagcttttga
    44221 acgtcggagt tcagatttac atggtattgc caatctcaaa ttgcaaactg ttgcctcatt
    44281 tcttggattt caaggtcagt ctcataatag tttagaggat gctcggatga cggcgcgtgt
    44341 ttacgaatcc ttcttagagt cggatcaagc tagggaattg ttagagacag aaagtagctt
    44401 atcaaacaat ccttttggtg gcttggactt gtctcaatta tttgactagg agtgcctatg
    44461 aaacctgaaa aacctaaaaa attgggtctt aaacagattt acctcaatct tgataaaatc
    44521 ctctttctat ttttcttgat ttttatgata gtggagtatt tgtgggtacc attcaattca
    44581 tggttggcta gcttcttatt agatcagaca ggttatcttt ttatttccta taacaatgtc
    44641 ttagccatcc ttactcattc tccattgatt agtctagctt ttttagcctt gattgtaatt
    44701 aaccttctgg ttgcttattt tcaaatagga ctcctcttta ttggtgctcg tcatctcctc
    44761 tataatgaaa agcgaaggct aattgagtat atccgcaagg ttttccatga aagttttgga
    44821 tttatgaaaa agctaacttg cgctaaagcc ttgtttatct ttttctatat agctatgctt
    44881 tttcctttta tacggaaaat gctgaagatt tattatctta ataaaatcgt cattccagag
    44941 tttatccaag cttatttaga agataaatat tggatgtggt ggctgagcat cctacttcta
    45001 tctcttatct ttctctatgt ctctgtcaga ttgatgtttg cccttccgaa gattgtatat
    45061 gatcagctga ctgttcgaga agcagtgatg tttagcttgg agaaaaccaa gaagagagtt
    45121 actttttatg cttggaattt attttacatc ttgctcaaag cacatttatt attttatctt
    45181 cctttgattc cttcattatt ggctcaaact ttggtagatg atatcactca gagagagtct
    45241 ctgattcttg gtattttgaa ttttgtcgtg attaaaaatc tctattatat ggctctgact
    45301 tattttttgg ttaaatttgt ttcatttttg acaggaaagg agctggatat gcttcctagg
    45361 agagaaaaag atcacatcgt gcgatggggt gtcatgactt gtgccagtct tttctttgcc
    45421 ttagaaggtt atatttatct ggaggctccc atggttcatc tacctcaact tatttctcac
    45481 cgaggggttt ccaatgcaaa tgggattcaa aatacagtag agtccttgga aactacagca
    45541 caactcaaac cagacttggt ggagacggac gtgcaggaaa caaaagatgg gcagtttgtc
    45601 atgatgcatg atgctaactt gaaaaatcta gcaggtatca ataaaagtcc tcaagactta
    45661 aacttggagg agcttaaagg gattgatatt tttgaaaatg gctaccagac taaaatttca
    45721 agctttgaag attatctcag tcgagccaac gaacttggtc aaaaattact aattgaaatt
    45781 aaaaccagta aaaaagatag tccagacatg atgaaccgct ttttagcccg ttatgctgca
    45841 aagctcaaga tttatggaca tcaaatccag tctttagact accatgttgt cgaaaaagta
    45901 agacagtatg atgccgaact gccagtttat ttcatcatgc cctacaattc tgtctttcct
    45961 aaaacaagag cgacaggata tactatggag tactcaacct tggatgaata ttttgtaagc
    46021 aaactatgga caacggatca gaaactttat gtctggactg tcaatgattc agaagctatc
    46081 agcaaatctc ttcacttagg agtagatgga gtgattacag atgatttgga aaaagttcag
    46141 cgggaaatag aagtagccca agaagatcca gaatatacgg atttgctctt gaaaaaagca
    46201 ttggaattct ttgaatttta gtaataaaaa agaggaacgg ttgttcctcc catgataggt
    46261 aagtattctt gtgaatgctt gcttttttgt ggttgcaatc cgtttacgag aattgtttgt
    46321 attgttcttg tttcaattta ctttatagtg ctttgaagtt ggaatgctac actataactt
    46381 ct
//
LOCUS       DAVLZS010000011        44914 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLZS010000011 DAVLZS010000000
VERSION     DAVLZS010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.011"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(122..931)
                     /locus_tag="VYO88_000648"
     CDS             complement(122..931)
                     /locus_tag="VYO88_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1718793.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGIGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(933..1736)
                     /locus_tag="VYO88_000649"
     CDS             complement(933..1736)
                     /locus_tag="VYO88_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1718794.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1746..3233)
                     /gene="tacF"
                     /locus_tag="VYO88_000650"
     CDS             complement(1746..3233)
                     /gene="tacF"
                     /locus_tag="VYO88_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1718795.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRAFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3589..4296
                     /locus_tag="VYO88_000651"
     CDS             3589..4296
                     /locus_tag="VYO88_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1718796.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVLHAEDLVDKYLPLHKERIIITKGGADRNTSIENIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIKLAQNHDAVDTVVEAVDTIVESTNGQFITGIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4301..5323
                     /locus_tag="VYO88_000652"
     CDS             4301..5323
                     /locus_tag="VYO88_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1718797.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLL
                     LVGSSRSGRIDFENAIQMMKVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5340..6209
                     /gene="licA"
                     /locus_tag="VYO88_000653"
     CDS             5340..6209
                     /gene="licA"
                     /locus_tag="VYO88_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1718798.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGTDEK"
     gene            6199..7077
                     /locus_tag="VYO88_000654"
     CDS             6199..7077
                     /locus_tag="VYO88_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1718799.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7089..7778
                     /locus_tag="VYO88_000655"
     CDS             7089..7778
                     /locus_tag="VYO88_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1718800.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7874..8722
                     /gene="dprA"
                     /locus_tag="VYO88_000656"
     CDS             7874..8722
                     /gene="dprA"
                     /locus_tag="VYO88_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1718801.1"
                     /translation="MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKTVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9606..10649
                     /locus_tag="VYO88_000657"
     CDS             9606..10649
                     /locus_tag="VYO88_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1718802.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10816..12903
                     /gene="topA"
                     /locus_tag="VYO88_000658"
     CDS             10816..12903
                     /gene="topA"
                     /locus_tag="VYO88_000658"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1718803.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFEPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKLKLTSNDEVKEILSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13009..13368
                     /locus_tag="VYO88_000659"
     CDS             13009..13368
                     /locus_tag="VYO88_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1718804.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13461..14093
                     /locus_tag="VYO88_000660"
     CDS             13461..14093
                     /locus_tag="VYO88_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1718805.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQLEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            14137..14793
                     /locus_tag="VYO88_000661"
     CDS             14137..14793
                     /locus_tag="VYO88_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1718806.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14812..15906
                     /locus_tag="VYO88_000662"
     CDS             14812..15906
                     /locus_tag="VYO88_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV1718807.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTLEEYGAIFKYLIENVKTERQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            15918..16955
                     /gene="leuB"
                     /locus_tag="VYO88_000663"
                     /pseudo
     CDS             15918..16955
                     /gene="leuB"
                     /locus_tag="VYO88_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            16952..17221
                     /locus_tag="VYO88_000664"
     CDS             16952..17221
                     /locus_tag="VYO88_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1718808.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17225..17584
                     /locus_tag="VYO88_000665"
     CDS             17225..17584
                     /locus_tag="VYO88_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1718809.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKFLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17746..18369
                     /locus_tag="VYO88_000666"
                     /pseudo
     CDS             17746..18369
                     /locus_tag="VYO88_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            18535..20466
                     /locus_tag="VYO88_000667"
     CDS             18535..20466
                     /locus_tag="VYO88_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV1718810.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVMGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILSGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNTAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            20453..21769
                     /locus_tag="VYO88_000668"
     CDS             20453..21769
                     /locus_tag="VYO88_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV1718811.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEESFKAIIDEEVGRK"
     gene            21944..22930
                     /locus_tag="VYO88_000669"
     CDS             21944..22930
                     /locus_tag="VYO88_000669"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1718812.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            22994..23065
                     /locus_tag="VYO88_000670"
     tRNA            22994..23065
                     /locus_tag="VYO88_000670"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23027..23029,aa:Arg,seq:ccg)
     gene            23248..23946
                     /locus_tag="VYO88_000671"
     CDS             23248..23946
                     /locus_tag="VYO88_000671"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1718813.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            23937..27476
                     /gene="smc"
                     /locus_tag="VYO88_000672"
     CDS             23937..27476
                     /gene="smc"
                     /locus_tag="VYO88_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1718814.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            27473..28267
                     /locus_tag="VYO88_000673"
     CDS             27473..28267
                     /locus_tag="VYO88_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1718815.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            28267..29085
                     /locus_tag="VYO88_000674"
     CDS             28267..29085
                     /locus_tag="VYO88_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1718816.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            29089..30366
                     /gene="ftsY"
                     /locus_tag="VYO88_000675"
     CDS             29089..30366
                     /gene="ftsY"
                     /locus_tag="VYO88_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1718817.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(30412..31899)
                     /locus_tag="VYO88_000676"
     CDS             complement(30412..31899)
                     /locus_tag="VYO88_000676"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1718818.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(32048..32788)
                     /locus_tag="VYO88_000677"
     CDS             complement(32048..32788)
                     /locus_tag="VYO88_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1718819.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(32788..34953)
                     /locus_tag="VYO88_000678"
     CDS             complement(32788..34953)
                     /locus_tag="VYO88_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1718820.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            35126..36079
                     /locus_tag="VYO88_000679"
     CDS             35126..36079
                     /locus_tag="VYO88_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1718821.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            36156..38144
                     /gene="uvrB"
                     /locus_tag="VYO88_000680"
     CDS             36156..38144
                     /gene="uvrB"
                     /locus_tag="VYO88_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1718822.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMTYNEEHDIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKVLD"
     gene            38154..38717
                     /locus_tag="VYO88_000681"
     CDS             38154..38717
                     /locus_tag="VYO88_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1718823.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            38683..39171
                     /locus_tag="VYO88_000682"
     CDS             38683..39171
                     /locus_tag="VYO88_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1718824.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            39245..39712
                     /locus_tag="VYO88_000683"
     CDS             39245..39712
                     /locus_tag="VYO88_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1718825.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(39709..40224)
                     /locus_tag="VYO88_000684"
     CDS             complement(39709..40224)
                     /locus_tag="VYO88_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1718826.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(40236..40763)
                     /locus_tag="VYO88_000685"
     CDS             complement(40236..40763)
                     /locus_tag="VYO88_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1718827.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(41027..41590)
                     /locus_tag="VYO88_000686"
     CDS             complement(41027..41590)
                     /locus_tag="VYO88_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1718828.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(41574..42125)
                     /gene="coaC"
                     /locus_tag="VYO88_000687"
     CDS             complement(41574..42125)
                     /gene="coaC"
                     /locus_tag="VYO88_000687"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1718829.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(42137..42826)
                     /gene="coaB"
                     /locus_tag="VYO88_000688"
     CDS             complement(42137..42826)
                     /gene="coaB"
                     /locus_tag="VYO88_000688"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1718830.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     IDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            43056..44726
                     /locus_tag="VYO88_000689"
     CDS             43056..44726
                     /locus_tag="VYO88_000689"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1718831.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATFRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
BASE COUNT        13937 a         7860 c         9768 g        13349 t
ORIGIN      
        1 atcaaggttt ttcaaaaacc ttgatatgat gcgttttatt gtgggaatat gtatttcatt
       61 ttctactaaa attatgtttt tgaataacct ctatcttagt agtttgtata atccccctca
      121 atcagttttt gcgataagct ttaatgctat gactatacca ctcttgcatt tcttttgatg
      181 gtggtgtcat ataatcgcca tacatctggg ttaaaaattg gtcatatttt ttaggaacag
      241 gcaacatacg gccctcaaac tcagttaaaa tcagttcttt aaaggtatca actgggaaga
      301 tttctttcat cccttcctta ccgatcccaa ttcctccttc atattgagga gtgttggtta
      361 cagcattttt gactagttga tcaattttct tgtaaaagta gcgaggattg acaaatcgga
      421 gagcgtacca gctacataat ctaagaaaat cttttagttt gctatcaccg tgaactgctc
      481 gtgatttttt gatataagct agttgacgaa gagccacata cttatagctc ttgtcgacaa
      541 tactcaagtc tgtaaatcga tcaattggga agacatcgat gaaaaggctg gtatcatgac
      601 gcttgtactt aacatggtct tctataacag tagaagtgtc caaaatcgat gcgaaattat
      661 ggaagtacca agaagatgta tcgtaggaaa gaaccttgta gcgagggtga ttttcttctt
      721 caataatctt cagtaaacgc tcataatcct cacgataaag ggaaatatca atatcatcat
      781 cccaaggaat catacctttg tggcggatgg ctccaagcat ggttccataa ctgagaaaat
      841 aaggaatatc atgtttctta caagtctcat caatatagtc cagcagggct agttgaattt
      901 ctttaatttc ttttttttct aaatattgca tcctaatcct ccaatttata agcgtgaaat
      961 tcatgactgt agaagcgttt ttcttctggt ggtagggtca tataatctcc ataaaattgt
     1021 gtcaaaatag tatcaaattt ttcaggtgca ggaaggctta aattctcaaa gggtaaatcg
     1081 attgttttat caaaggtacc acttgggaag acttcctttt ccttaaattt tgaaggaata
     1141 aaagccatat actgcccatt ttcacgacta tatttttgaa tttctttctc gattttattt
     1201 gcaaaataac gaggagaaac cggtcgaagg agcaaccaaa aggctgttcg tatccaatct
     1261 tttaaaaggc tatccttata gacaatattt ttatgtttac tgaaagacag cagtttgaag
     1321 ctttccagtt tataacaagt atcaatgacc ttaggatcat caaagcgatc tatagggaaa
     1381 atatcgataa agataccaga ctcataggtt tttgtatttc gagtatcaat aattttagtc
     1441 gtactgtcgg ttatcttgat aaagttgtta aagtagttct tatcagtttc taaggatagg
     1501 agcttatact tgcttttttc cttttgaaaa atgttaataa atcgttggta gtcttctcta
     1561 ggcatggata aatcaatatc gtcgtcccaa gggataaagc cctcatgtcg aaccgcccca
     1621 atcagagtac cgtagttaat aatatagttg atattgtgct ttttacagag agtatcaata
     1681 taatccaaaa tttctaattc aatttgtttg gcatcttcaa cggttagttg tttcatttta
     1741 aactcctatg attttttaaa tttatttttt aaggctagga catggtttaa aaattcatag
     1801 aaaatgctat cttttgtgaa gacaagtaga ctaatataag agatagctga tagcaagaca
     1861 atcaaaccag tattaatcaa aaatggcaaa ttaatgacca tatccacagg atacatgaaa
     1921 ttaatcagga aataaattgc tacaaaggaa agtgaaaaga gagagtatcg aacagtatag
     1981 ctaaagatat gtcccaagtg gatgagttgt tttctatgga tgaaaatgat atagaaaaca
     2041 agtagagaag tctctgataa catagttgtc agtaagtagt attcaggagc cacgatatgg
     2101 ttgaaaaaga ggagactatt caagcccaaa tttagtagcc cagcaaagac tgtatagact
     2161 gtgatacgtt tttcatagcc attggtaaag agaatttggg aaccaagaat ggtatctaag
     2221 gccagaataa tcgtacgaaa agcgaagaga gaggtcaaga tgccgcctcc gatatatttt
     2281 tcactaccgt aaagtaggat ggcatttggt cctaaaacca tgagtccaaa actcagtgga
     2341 atgataaaga agttaaagat tcgactacct ctattaacca gagaaacata ggcttctttg
     2401 tctcctttcc ccagatagta actgagacga ggcacactca ctccaattgc acctgttaca
     2461 accccagcta taacggtcac aattcgctga gctatggtat agtaactaac gttgacatca
     2521 atccctgttt taacgaggaa gaggcgatct aaaaaagtga agagcatatt ggcattggca
     2581 aagactaaca tggctgtcag agggagaaag agtggtttaa aatcacttag gtgaatctta
     2641 acaagtttga tgtctctttt aatccaaaaa taactaatca ggtagttaat cagcgtcgat
     2701 aaactcatca caagtgtata gacaacaata tcgtgttcat ttttaacaaa taagaaaata
     2761 gagaccagca tcaggatacg gatgaaggca gttttgtaaa agagaaaact gtaattttcc
     2821 agagcttcat tgacccattc gattgaaaaa atctgggcaa tgagttgaat ccccataaca
     2881 aggtagacct ttttgacgat tggattatca gtaaagaaga gaggataggc taggatatag
     2941 acagcagtgg tcaaaatcgt acaagcgatg cacaaataaa aaagactaga aaaggctctg
     3001 ttaagatctt ttttgttatc cttgacatta ctgatagccc ttaaaccgta gttatagaca
     3061 ccataagttg caaagggcaa gaaaaatgac aaaatagtgt cgactgagtt gaagtaacca
     3121 tagtcagttc ggtccaagac acgcgcgaca taggttccag ttaggatggg aaaaataata
     3181 ttcaagacac gaattcccat gtaagataga gcatttaatt ttatactttt cattcaattt
     3241 acctcgtttt tcattatatc ataaagttag ctaataagaa atgaagggca gtaagtcaag
     3301 taatcacttt gaagtttcaa atcttaaatt ttaagttttc tttaaggaaa gtatattatt
     3361 ctgaaagact ctaaaatttc gcagtcattt attagtaatt gctacagaat tcctagtcat
     3421 tactagaaat aggcttgttt ctttgaataa tagaactgca taattctcct attctagaag
     3481 gggaggacca gtatttcttt catgatagga ctagattgtg gtatatagga ctagattgtg
     3541 gtataataga gagaataagt ttttttagta agacaaagga gaaaatagat gatttatgca
     3601 ggaattcttg ccggtggaac tggcacacgc atgggaatca gtaacttgcc aaaacaattt
     3661 ttagagctag gtgatcgacc tattttgatt catacaattg aaaaatttgt cttggaacca
     3721 agtattgaaa aaattgtagt tggtgttcat ggagactggg ttttacatgc agaagatctt
     3781 gtagataaat atcttcctct tcataaggaa cgtattatca ttacaaaggg tggtgctgac
     3841 cgcaatacaa gtattgagaa catcattgaa gccattgatg cttatcgccc gcttactcca
     3901 gaggatatcg ttgttaccca cgattctgtt cgtccattta ttacgcttcg catgattcaa
     3961 gacagtatca aacttgctca aaatcatgac gcagtggata cagtagtaga agcagtggat
     4021 actatcgttg aaagtaccaa tggtcaattc attacaggta ttccaaatcg tgctcacctc
     4081 tatcagggac aaacacctca aacattccgt tgcaaggact tcatggacct ttatggatct
     4141 ctttctgatg aagagaagga aatcttgaca gatgcatgta aaatctttgt gatcaaagga
     4201 aaagatgtag ccttggccaa aggcgaatac tcaaatctga agattacaac cgtaacagat
     4261 ttgaagattg caaaaagtat gattgagaaa gactagtaaa atgattaatc aaatttatca
     4321 actaactaaa cctaagttta tcaatgtcaa atatcaggaa gaggctattg accaagagaa
     4381 tcatatcctt atccgtccca actacatggc tgtctgtcat gcggatcagc gttactacca
     4441 gggaaaacgt gatcccaaga ttttgaataa aaagcttcca atggcaatga ttcacgagtc
     4501 atgtggaacc gtcatttctg acccgacagg aacctacgag gttggtcaaa aagttgtcat
     4561 gattcccaat cagtctccta tgcagagtga tgaagaattc tatgaaaact acatgacagg
     4621 gacccatttc ttgtctagtg gatttgatgg ctttatgaga gagtttgttt ctctccctaa
     4681 agatcgtgtg gtggcttatg atgctattga agatacggtt gcagccatta cagagtttgt
     4741 cagtgtgggc atgcacgcta tgaatcgtct attgactctt gctcatagca agcgggagcg
     4801 gatcgccgtt attggagatg gaagtttagc ttttgtggtt gccaatatta tcaattatac
     4861 tttgccagaa gcagagattg tggttattgg tcgtcattgg gaaaagttgg aactcttctc
     4921 atttgccaaa gaatgctata ttacggataa tattcctgaa gagttggcct ttgaccatgc
     4981 ttttgaatgt tgtggtggtg atggtactgg accagctatt aatgacttga ttcgctacat
     5041 tcgtcctcag ggaacaattc tcatgatggg agttagcgaa tataaagtca atctcaatac
     5101 tcgcgatgcc ttagaaaagg gcttgctctt ggttgggtca tctcgttctg gtcgcattga
     5161 ttttgaaaat gctatccaaa tgatgaaagt caagaaattt gccaatcgtc ttaaaaatat
     5221 cctttatcta gaagaacctg taagagaaat taaagatatt caccgtgtct ttgcaaccga
     5281 tttaaataca gcctttaaaa cagtgtttaa gtgggaagta taagtcctgg aggttaattg
     5341 tggagaaaat cattaaagaa aaaatttctt ccttacttag tcaagaagaa gaagtcctca
     5401 gtgttgaaca actgggtgga atgaccaatc aaaactattt ggccaaaaca acaaataagc
     5461 aatacattgt taaattcttt ggtaaaggga cagaaaagct tatcaatcga caagatgaaa
     5521 agtacaatct tgaactacta aaggatttag gcttagatgt aaaaaattat ctttttgata
     5581 ttgaagctgg catcaaagta aatgagtata tcgaatctgc gattacgctt gattcaacgt
     5641 caatcaagac caagttcgac aaaattgctc caatattaca aactattcat acatctgcta
     5701 aggaattaag aggagaattt gctccttttg aagaaatcaa aaaatacgaa tccttgattg
     5761 aagaacaaat tccttatgcc aactatgaat ctgttagaaa tgcagtcttc tccttagaga
     5821 aaagactggc tgacttaggt gttgacagaa aatcttgtca tatcgatttg gtgcctgaaa
     5881 actttatcga atcacctcaa ggacgacttt atttgattga ctgggaatat tcatcaatga
     5941 atgatccaat gtgggatttg gctgccctct ttttagagtc tgaattcact tcccaagagg
     6001 aagaaacttt cttatctcac tatgagagtg accaaacacc ggtttctcat gaaaagattg
     6061 ctatttataa aattttacaa gatactattt ggagtctatg gactgtctat aaggaagagc
     6121 aaggtgcaga ttttggttac tatggtgtga atcgttacca aagagctgtt aaaggtttgg
     6181 cttcttatgg aggaacagat gaaaagtaaa aacggagttc cttttggcct tctctcaggt
     6241 attttctggg gcttgggtct aacggttagt gcttatatct tttcgatttt tacagatttg
     6301 tcaccctttg tggtggctgc agctcatgat tttttgagca tctttatctt actagctttt
     6361 ctcttggtaa aagaagggaa agttcgcctc tcaattttct taaatattcg caatgtcagt
     6421 gttatcatcg gagccttgct agcaggccct atcggtatgc aggccaatct ttatgcagtt
     6481 aagtatatcg gaagttcttt agcttcatct gtatcggcta tttaccctgc gatttcagtt
     6541 ctattggctt tcttcttttt gaagcacaag atttcgaaaa atactgtatt tgggattgtc
     6601 ttgattattg gagggattat tgcccagacc tataaggttg aacaggttaa ttctttctac
     6661 attgggattc tttgtgcttt ggtttgtgct attgcatggg gaagtgagag tgttcttagc
     6721 tcttttgcca tggaaagtga attgagtgaa atcgaagccc tcttaatccg tcaagtaact
     6781 tcgttcttgt cctatcttgt gattgtgctc ttctctcatc agtcatttgt tgcagtagcc
     6841 aatggacaat tgctaggtct catgattgtc tttgtagcct ttgatatgat ttcctatttg
     6901 gcttattata tcgctatcaa tcgcttgcaa ccagccaagg ctacaggctt gaacgtgagc
     6961 tatgtagtat ggacggtctt gtttgcagtt gtttttttgg gtgcaccgct agatatgctg
     7021 accattatga cgtcacttgt cgtcattgct ggagtttata ttattattaa agaataaagg
     7081 agattcgtgt gaaagccatt atcttagcag cgggattggg aactcgcttg cgtcctatga
     7141 ctgaaaatac ccctaaagcc ttggttcagg ttaatcaaaa acctttgatt gaataccaaa
     7201 ttgagtttct caaagaaaaa ggaatcaatg acatcatcat cattgttggt tatcttaaag
     7261 aacaattcga ttacttaaaa gaaaaatacg gtgttcgcct cgttttcaat gataaatacg
     7321 ctgactacaa taacttttac tctctctatc ttgtaaaaga agaattggcc aacagctatg
     7381 ttattgatgc tgacaattat ctctttaaaa atatgttccg caatgatttg actcgttcga
     7441 cttattttag tgtttatcgt gaagattgta ccaacgaatg gttcttggtc tatggagatg
     7501 actacaaggt tcaagacatt attgttgata gcaaggcagg tcgcatcctt agtggtgtat
     7561 ccttctggga tgctccaact gcagaaaaga ttgtcagctt tatcgataag gcttatgcaa
     7621 gtggcgaatt tgttgatctc tattgggaca atatggttaa ggataatatc aaagagctag
     7681 atgtctatgt tgaagaatta gaaggcaata gcatttatga gatcgatagt gtccaagact
     7741 atcgtaaatt agaagaaatt cttaaaaacg aaaattaaag attccaacat ctgacaaaat
     7801 agtcggatgt tttttgattt tttacgaact tttacgaata gatagatgag tagaaaaaga
     7861 aatggagtta tttatgaaaa tcacaaacta tgaaatctat aagttaaaaa aatcaagttt
     7921 gaccaatcaa cagattttga aagtgctaga atacggtgaa aatgttgatc aggagctttt
     7981 gttgggtgat attgcagata tatcaggttg ccgtaatcca gccgttttta tggaacgtta
     8041 ttttcagata gacgatgcgc atttgtcgaa agagtttcaa aaatttccat ctttctctat
     8101 tttagatgac tgttatcctt gggatttgag tgaaatatat gatgcgcctg tacttttatt
     8161 ttacaaggga aatcttgacc tcctgaaatt cccgaaggta gcggtcgtgg gcagtcgtgc
     8221 ttgtagcaaa cagggagcta agacagttga aaaagtcatt caaggcttgg aaaatgaact
     8281 ggttattgtc agtggtctgg ccaagggcat tgacacagca gctcatatgg cagctcttca
     8341 gaatggcgga aaaaccattg cagtgattgg aacaggactg gatgtgtttt atcctaaagc
     8401 caataaacgc ttgcaagact acatcggcaa tgaccatctg gttctaagtg aatatggacc
     8461 tggcgaacaa cctctgaaat ttcattttcc tgcccgtaat cgcatcattg ctggactttg
     8521 tcgtggtgtg attgtagcag aggctaagat gcgttcaggt agtctcatta cctgtgagcg
     8581 agcaatggaa gaaggacgcg atgtctttgc tattcctggt agcattttag atggactatc
     8641 agacggttgc catcatttga ttcaagaagg agcaaaattg gtcaccagtg ggcaagatgt
     8701 tcttgcggaa tttgaatttt aaaaatgacc taagctagaa ttctaagaaa aaatcaattt
     8761 taagagaaaa tgaacccaac atttccataa taaaacgcat attagcaagt ttttaacact
     8821 tgataatatg cgttttttct aagtggatta gtagagtaga ggatttttct catataatac
     8881 tcttcgaaaa tctcttcaaa ctacgtcagc ttccatctgc aacctcaaaa cagtattttg
     8941 agctgacttc gtcagtctta tctacaacct caaagcagtg ctttgagcaa cctgtggcta
     9001 gcttcctagt ttgcgctttg attttcattg agtataaggg aaagtatagt gaattgaaat
     9061 aagatgtgaa caactctatc aggaaagtca aattaattta tagaaatatt ttagcagcca
     9121 aggtgcactg ttatagattc aatacactat aatttagtgt aattgagaaa ggagaaatga
     9181 ttgtgattga tgttggctag gttatgttca atgattccta ccgtctcaaa tcttgtcagt
     9241 aaggaaaaat aaattcttca aaagtagaga ttacaaggct tgtttaagaa agaattcaaa
     9301 gaccttgaca aataaaaata aaatggttat tataagaaat ggtctaaaat agatgatgat
     9361 acttttcgaa aatcttttta cgtcagctca gctttgcctt gctgtgtttt gagcaagcta
     9421 cggttagctt ccgagtttga ttttcattta ctagaaatga aactgatgag agatatcagt
     9481 agacatttga gtcaggatat tatggaaaat gataaaaaga gctcgtgaga ttggcatatc
     9541 agactactaa agtattgagt ttgttaggat tttagcgact agttagctgg gaaaggaaga
     9601 tatttgtgac aaataataaa ctgtattcgt tgatagaatt tagaaataaa atatatgaag
     9661 aattagaact ttccagaagt gatttagcga ttttactatg tgccatgctt atcgcctcta
     9721 tcggattaaa tatggattcg actcccgtga ttattggagc catgttaatc tctcctttga
     9781 tgacacctat tctgggagtg gggctctctc tagctatatt tgattttaaa ttgttaagaa
     9841 aatcttttaa aatattagct attcaaattc ttgcgagtct aatagcttca acactttatt
     9901 tttatctttc tcccatttcg tatgctagtt cggagattgt tgctagaacc tctccgacta
     9961 tttgggatgt tctcattgct tttgtaggag ggatagcagg tattattggt gctaggaaaa
    10021 aagagaccaa taatattgtt cctggtgttg ctattgcaac cgccttgatg cctcctcttt
    10081 gtacagtagg ttatgctatt gcttctgcta atctaaaatt tatcataggc tcctcttacc
    10141 tattcctcat caattgtagc tttattgtca ttgcgactta tataggtgtt aggttgatga
    10201 tggttaagaa acattatttt aaagataatg aagaagactc taaaatgcgt aggattttgc
    10261 ttctagttgc tgttttgctg atgattccga gtttcatctc tgcaacgact ttagtgagag
    10321 aaacgttgaa aaaagagtcc cttaagaaat ttatatcaga gcagtttcag gggtataata
    10381 ttttgaaaaa aacctattct aaaaagactc ataccctaaa gctaaccatt tcaggaaatt
    10441 atttgacaga agaagaactc gatatgattt caagtaagag aggtgactat ggtttaagtg
    10501 atgtttctgt tcaagtttca caattgtctg attcagaaca acttagtaag gaagagctgg
    10561 tggagtattt cttccagtat atcaaggata aggaagcaaa agaaaaggag aaagccaata
    10621 aatttgatac agagtctgag gagcaataat ttcttgagaa tagctggttt ttctcgtgag
    10681 tcttctatgt atatcaaagg aagactgagg ttttaagtat aaaacttttc ttctattata
    10741 gtagctaagt cttgacaggg ttcaaaaaat ggtttacact ttataaagtt tattactttg
    10801 aaaaggtgtg atactgtggc tacggcaaca aaaaagaaaa aatcaacagt taaaaaaaat
    10861 ctagtcatcg tggagtcgcc tgctaaggcc aagacgattg aaaaatatct aggcagaaac
    10921 tacaaggttt tagccagtgt cgggcatatc cgtgatttga agaaatccag tatgtccgtc
    10981 gatattgaaa ataattatga accgcaatat attaatatcc gaggaaaagg ccctcttatc
    11041 aatgacttga aaaaagaagc taaaaaagct aataaagttt ttctcgcgag tgacccggac
    11101 cgtgaaggag aagcgatttc ttggcatttg gcccatattc tcaacttgga tgaaaatgat
    11161 gccaaccgtg tggtcttcaa tgaaatcacc aaggatgcag tcaaaaatgc ttttaaagaa
    11221 cctcgtaaga tcgatatgga cttggtcgat gcccaacaag ctcgtcggat cttggatcgc
    11281 ttggtagggt attcgatttc gcctattttg tggaagaagg tcaagaaggg cttgtcagca
    11341 ggtcgcgttc agtccattgc ccttaaactc atcattgacc gtgaaaatga aatcaatgcc
    11401 ttcgagccag aagaatactg gacagttgat gctgtcttta aaaagggaac caaacaattt
    11461 catgcttcct tctatggagt agatggtaaa aagctgaaac tgactagcaa tgacgaggtc
    11521 aaggaaatct tgtctcgtct gacgagtaaa gacttttcag tggatcaggt ggataaaaaa
    11581 gagcgcaagc gcaatgctcc tttaccctat accacttcat ctatgcagat ggatgctgcc
    11641 aataaaatca atttccgtac tcgaaaaacc atgatggttg cccaacagct ctatgaagga
    11701 attaatattg gttctggtgt tcaaggtttg attacctata tgcgtaccga ttcgactcgt
    11761 atcagtcctg tagcgcaaaa tgaggcggca agcttcatta cggatcgttt tggtagcaag
    11821 tattctaagc acggtagcaa ggtcaaaaac gcatcaggtg ctcaggatgc ccatgaggct
    11881 attcgtccgt caagtgtctt taatacacca gaaagcatcg ctaagtatct ggacaaggat
    11941 cagctcaagc tatataccct tatctggaat cgttttgtgg ctagccagat gacagcggcc
    12001 gtttttgata ccatggctgt taaattgtct caaaatggag ttcaatttgc tgccaatggt
    12061 agtcaggtta agtttgatgg ttatcttgcc atttataatg attctgacaa gaataagatg
    12121 ttaccggaca tggttgttgg agatgtggtc aaacaggtca atagcaaacc agagcaacat
    12181 ttcacccaac cgcctgcccg ttattctgaa gcaacactga ttaaaacctt agaggaaaat
    12241 ggggttggac gtccatcaac ctatgcgcca accattgaaa ccattcagaa acgttattat
    12301 gttcgcctgg cagccaaacg ttttgaaccg acagagttgg gagaaattgt caataagctc
    12361 atcgttgaat atttcccaga tatcgtaaac gtgaccttca cagctgaaat ggaaggtaaa
    12421 ctggatgatg tcgaagttgg aaaagagcag tggcgacggg tcattgatgc cttttacaaa
    12481 ccattctcta aagaagttgc caaggctgaa gaagaaatgg aaaaaatcca gattaaggat
    12541 gaaccagctg gatttgactg tgaagtgtgt ggcagtccaa tggtcattaa acttggtcgt
    12601 tttggtaaat tctacgcttg tagcaatttc ccagattgcc gtcataccca agcaatcgtg
    12661 aaagagattg gtgttgagtg tccaagctgt catcagggac aaattattga gcgaaaaacc
    12721 aagcgtaatc gcctcttcta tggttgcaat cgctatccag aatgtgaatt tacctcttgg
    12781 gacaagcctg ttggtcgtga ctgtccaaaa tgtggcaact tcctcatgga gaaaaaagtc
    12841 cgtggtggtg gcaagcaggt tgtttgtagc aaaggcgact acgaggaaga aaagattaaa
    12901 taagaggagg ggcccgaaag taaatttcag gctccttttg gttagaactt gacaaaatac
    12961 atcattttat gcgaaactag aagaagatta ttttaactag gagaagttat gcgtcttatc
    13021 tatctgataa ttggtttttt atcactggcc ttggctattg ttggggttgt tttaccctta
    13081 ttgccgacaa cgcctttcct tttgttgtct attgcttgtt tctccagaag ttccaagcgt
    13141 ttcgaagact ggctttatca taccaagctc tatcaaacat atgtagctga ttttcgcgag
    13201 actaagtcta ttacgcgtga acgaaagaaa aaaatcatcg tctctatcta cgtcttgatg
    13261 ggaatttcta tttattttgc acctctttta ccagtcaaaa ttggtctggg tgctttgacc
    13321 atctttatca cttattatct cttcaaggtc attccagaca aagaatagtt aaaacagtag
    13381 ttatttgcct tgataaaatt gaaagcatat tcataacaat atgatataat aaatttgaag
    13441 taatattcaa ggagaatcaa atgatttacg aattttgtgc tgaaaatgtg actttacttg
    13501 aaaaagcgat gcaggctgga gctcgtcgga ttgaactctg tgataatcta gcagttggtg
    13561 ggacaacacc cagctatgga gtgactaagg cagcggttga actggcagct aactacgata
    13621 caaccatcat gaccatgatt cggccacgtg gtggtgactt tgtctataat gacctagaaa
    13681 ttgctatcat gctagaagac attcgtttga ctgctcaggc tggaagtcaa ggggttgtat
    13741 ttggaacttt aactgctgat aaaaagttgg ataagcctaa tctggaaaag ttaattgctg
    13801 catcaaaagg aatggaaatt gtctttcaca tggcctttga tgaactaagt gatgaagatc
    13861 aactggaagc tattgactgg ctcagtcaag ccggtgtcac tcgtatccta actcgtgctg
    13921 gtgtgtctgg cgactcctta gaaaaacgtt ttgttcacta tcacagaatt ttggagtacg
    13981 ctaaaggtaa aattgaaatt ctaccaggtg gggggattga ccttgaaaac cgtcaaacct
    14041 ttatcgacca ggtgggggta acacaattgc atggtactaa ggttgttttt taaaaaatag
    14101 aaaggaactg ctagccttgg gtagcagttt tcacttatgt ttgaaatttt taaatcctat
    14161 caatttaatc aagaaaaggc tcatgattat ggttttatag aaaatagcga agtctggaca
    14221 tatagttgcc agattttgca aggtgacttt gtcatgactg tgtccatcac tgctgataat
    14281 gtgaactttc aagtctttga ccaagagact ggtgacctct atcctcacgt tcatatggaa
    14341 agcatgaggg gaagttttgt cggaaatgtc cgtgaggctt gtctggagat tctttaccag
    14401 attcggaagg cttgttttga tgtgcaagat tttatctgtc atcagactaa gcgtatcatg
    14461 actcaagttc aggaaaagta tggaaaccag ttggagtatc tgtgggaaaa atcgcctgat
    14521 acagctgtat tgcgccatga aggcaatcaa aagtggtatg ccgtcttgat gaaaatctct
    14581 tggaataagc tggaaaaggg cagagaagga caagtggaag cagtcaacct caagcatgac
    14641 caagtagcta atttactttc acaaaagggg atttatccag cctttcatat gagcaagcgc
    14701 tactggatta gtgtgtccct tgatgatact ttatcagatg aagaagtact ggaattgata
    14761 gaaaaaagtt ggaacttaac ctctaaaaaa tgaaatattt taataatttt catgaacttt
    14821 caattagcta aatattcttt actgaagaaa ttttcagaaa atataggatt taccacacta
    14881 gaggaatatg gtgccatctt caaatacctg attgagaatg tcaagacgga gcgtcagatc
    14941 atttattcgc ctcactgtca tgatgacctc ggaatggcag tggcaaatag ccttgctgct
    15001 gtcaagaatg gtgcaggacg tgttgaaggg actatcaatg gtattaggga gcgagctgga
    15061 aatgctgctt tggaagaaat tgcagtggct ctcaatattc gccaagatta ctaccaagta
    15121 gaaaccagta ttgtcctaaa tgagaccatc aatacgtcag aaatggtttc tcgcttctct
    15181 ggtattccag ttcctaaaaa caaagccgtc gttggtggca ataccttctc ccacgaatct
    15241 ggtattcacc aagatggagt ccttaaaaat cctctcactt atgagatcat cacacctgaa
    15301 ttggttggtg ttaagattct gcttggaaaa ttatctggtc gccatgcttt tgttgagaaa
    15361 ctgagagaat tggccctaga ttttacagaa gaggatatca aaccactctt tgctaagttc
    15421 aaggcactgg tcgataagaa gcaagaaatc acagatgcag atattcgagc tttggtagct
    15481 ggaaccatgg ttgaaaatcc agaaggcttc cactttgatg atttacaact tcaaactcat
    15541 gcagataatg acattgaagc gctcgttagc ctagccaata tggatggtga gaaagtcgaa
    15601 tttaatgcga cagggcaagg ttccgttgaa gcaatcttta atgctatcga taagttcttt
    15661 aaccaatctg ttcgtttggt gtcctacact atcgatgcgg taacagatgg aatcgatacc
    15721 caggatcggg ttttggtcac tgttgaaaac agagatacag aaaccatctt taatgcagca
    15781 gggcttgatt ttgatgtgtt gaaggcttct gctattgtct atataaacgc taataccttt
    15841 gttcaaaaag agaatgcagg tgagatggga cgcagtgttt cttaccacga tatgcctagt
    15901 gtgtaaagga gaaggctatg gcaaagaaaa tagtagctct agcaggagac ggaattggcc
    15961 cagaaatcat ggaggttggt ttagaagttc tggaggctct agctgaaaaa acaggttttg
    16021 actatgagat tgacagacga ccgttcggag gtgcagatat tgatgcagca tgacctccct
    16081 tacctgatga aacccttaag gcaagtaggg aagcagatgc tatcctacta gcagctatcg
    16141 gtagtcctca gtatgatgga gcagtggttc gccctgaaca aggcctgatg gctctccgta
    16201 aggaactcaa tctttacgct aatattcgtc ctgtaaaaat ctttgacagt ctcaagcatt
    16261 tgtcactact caaactggaa cgaattgctg gtgtagactt tgtcgtggtg cgtgaattga
    16321 caggcgggat ttactttgga gatcatattc ttgaagagcg caatgcgcgt gatatcaaca
    16381 actatagcta tgaggaagtg gagcggatta ttcgcaaagc ctttgaaatt gcaagaaatc
    16441 gcagaaaaat cgttactagt atcgataagc aaaatgttct agcgacctca aaactctggc
    16501 ggaaagtagc tgaggaagtc gcacaggatt tcccagatgt aaccttggaa catcagctgg
    16561 tagactcagc tgctatgctt atgattacca atcctgctaa gtttgatgtt attgtaacgg
    16621 agaatctttt tggagatatt ttatctgatg aatcaagcgt cttatctggt acacttgggg
    16681 ttatgccatc agccagtcat tctgaaaatg gaccaagtct ctatgaacct attcacggtt
    16741 cagcacctga tattgcaggt caaggaattg ccaatcctat ttccatgatt ttatcagttt
    16801 ccatgatgtt gagagatagt ttcggacgtt atgaggatgc agagcgtatc aaacgtgctg
    16861 ttgagacaag tctggcggca ggaattttaa cgagagatat aggaggtcag gcttcaacaa
    16921 aggaaatgac ggaagctatt attgcaaggt tatgaagtta gacgaaaaaa ttactctagt
    16981 ccttttgatt tggaatgtca tcattttctt gatttatggc attgacaaat tcaaggcaag
    17041 aagaagagct tggcgcatcc aagagaaaat cttactcatt ttagccctta cttgtggtgg
    17101 ttttggggcc tggttagctg gaatcacttt tcaccacaag actcgaaaat ggtactttaa
    17161 aacagtttgg tttcttggga tggtgaccac actagtagcc ttatatttta tttggaggta
    17221 atggatggca gggtcttcga gggaatacgc tgcttgggct ctagcggact atggttttaa
    17281 ggtcgtgatt gcaggatctt tcggtgacat tcattacaat aatgaactca ataatggcct
    17341 gttgccaatc gttcagccta gagaggttag agagaaacta gcccagctaa aaccaaccga
    17401 ccaggtaact gtggacttgg aacaacaaaa aatcatctca ccagttgaag aattcacctt
    17461 cgagatagat agcgagtgga aacataaatt cctaaatagt ttggatgata tcggtattac
    17521 cttgcagtat gaagagttga ttgctgctta tgaaaaacaa cgaccagcct actggcagga
    17581 ttagaaaaaa tagaaaagga aatatagtaa actgaaataa gatgtaaaca aatgaattgg
    17641 agcttaacat ccatttccag caatttttta gaaactacag tggactattc tggattcaac
    17701 acattataaa attatgacaa aacacattca caagaaggct acgacatttt aaaaggtgag
    17761 ggcggatgta tcgtttgccc tactaaagtt ggttacatta tcatgaccag caacaaggca
    17821 ggacttgagc gtaagttcgc agccaaagaa cgtaagcgta acaaaccagg tgttgttctc
    17881 tgcggtagca tggatgaact tcgcgcttta gcgcaactca acccagaaat tgaagcattc
    17941 tactaaaaac attggatgaa gatattcttc ttggttgtat ccttccttgg aaaccagaag
    18001 cctttgaaaa actcaaagca tacggggatg gccgtgaaga acttatgact gatgtacgtg
    18061 gtactagctg ttttgttatc aagtttggaa aagcaggtga acaattggct gccaagcttt
    18121 gggaagaagg taaaatggtc tacgcctcat atgcttcaat gacaaaacga ttgaaactcg
    18181 ctatgagagc aaggtgtaat ggtgtctatg gtcgataagg acggcaaact catcccagaa
    18241 caaggaggag cacgttcaac ttcaccagca ccagttgtga tccgtaaagg gcttgacatt
    18301 gataaaatca tgatgcacct gtcagatact tttaactcat gggactaccg tcaggttgag
    18361 tattattaag ataaaaaaag aagtctagtg ttatgagata ttaaagctcc taacactgga
    18421 ctttttgttt agaatttctt ttctttttct ataggatatg gtattctatg tagaaaatat
    18481 atgttaataa gtaatgccaa tatttaaaca tcattagtaa aaggagttag attgatgaat
    18541 aaaagaaaag ttagtttaga agatttttat aaatggtata gtctaaataa agaagagtta
    18601 ttaaataagg caactgttgg tgaaaagttt aatgataaat taaaagaaga gtttctccag
    18661 gaatggcctt tggataggat tttaacaatg tcaatcgatg aatatgtaat gggaaaggga
    18721 cagcaaaata agtctttatg ctacgctctt gagaagggaa aatacaaaaa tctatttctt
    18781 ggaatttctg gtggctcagc ttcaaaattt ggtatttatt ggaataaaaa aacaaacaaa
    18841 tataaagatc aagctaataa tgagatttca gagttggatc agcgattttc aaaattaaaa
    18901 tcagatttgt atgaaattat caaagaaggt attcgtttta actttgaaaa tcctattttt
    18961 gatatgaaaa gatcaacaaa tgaatttatt ggtcgttctg ctatggtgac aaaattactt
    19021 tgtatctatt ctgagggaga tcctttcttt ggtgtaaata ttaatagtca gaaagaattt
    19081 tggaaccact ttgtttctca gacaaatcaa ggtggacctt atctgcaaaa tcataaaata
    19141 attgaactgg tgtccaaaac ttatcctgag ttggagccat cgaaattagg aactatgctt
    19201 tttgagtatt ctaagctttt tatggaaaat aaggaagaca atagtacaat ggattcatca
    19261 aacaattttc gtcatcaatt aactcaatct ctattaaagt ctccaaacct tatccttagt
    19321 ggtgctcctg gcacaggaaa gacttatctt gctaaagaaa ttgccaaaga attaacggat
    19381 ggcaacgaag accaaatcgg atttgtacaa tttcacccat catatgatta tacggatttt
    19441 gtagaaggtt taagaccagt atcaaatggg gatggagcta ttgagtttag gctacaggac
    19501 ggtattttta aagatttttg tcagaaagca aaagaaaccc aattgattgg aggacaagat
    19561 aattttgatg aggcttggga ttcttactta gaatatataa atgttgctga agaaaaagaa
    19621 tatataacaa aaacatctta cttatctgtt aatagtagac aaaatttgtc agtaaattat
    19681 gatagtggtg ttccaggatg gtcactacct agcaaatatg tttacgagtt gtataaagat
    19741 aaaaattata ataagcaaga atactacaaa agtggtggaa aaactgtcct agaaacattg
    19801 agaaagagat ttggtttgaa agactatgtt tccccaacag aaattgatac tgataagaaa
    19861 ttcgtcttca tcatcgatga aatcaatcgt ggggagattt ctaagatttt tggcgaactc
    19921 tttttctcta tcgaccctgg ctatcgtggt gaaaaaggaa gtgtttctac ccaatatgca
    19981 aatctacacg aaactgatga aaagttctat atccccgaaa atgtttacat catcggaact
    20041 atgaatgata ttgatcgttc agtggatacc tttgattttg ctatgcgtcg tcgttttcgt
    20101 tttgttgaag ttactgccga gggtcaagtt ggcatgttgg ataaagagct gaatatccat
    20161 gcagaagaag caaaaattcg tctaagaaac ttgaacactg ctatcgaaaa tgttcaggaa
    20221 ttaaacagtc attatcatat tggaccaagt tattttctta agttgaagga tgtagatttt
    20281 gactatgaat tactctggtc tgattatatt aagcctctcc tagaagacta cttgcgaggt
    20341 tcttatgatg aggttgaaac tttggaaact ttgaaaaaag catttgaact gacaaataat
    20401 gagcaaaaag atcaggcagt agctgatgac aatgaaggtg atgaaaacga tgatgcggat
    20461 tactgataat caacacaaga ttattaaaga aaaatttgtt gaagaatatc ctaaactaag
    20521 caatcttctt ttagacagaa ccttggaaag tctatcccaa gatgaacgta ttttcatttt
    20581 tccaaatgat ttgactcata ctcctgattt ggataaggac caaaagattt ttgaaacagt
    20641 caatcagaaa atcaagacag gaaatgtgat tggttttctt ggatatggtc aggaaagatt
    20701 aacgatttcc tcacgatttt ctgatgagag taatgaccat tttttacatt atctcttaaa
    20761 caaggttctt catatcaatc tcactagttt agatgttgct ttgtctcgtg aagagaggct
    20821 ttatcaactt ttgatgtatc tcttccccaa gtatctacaa gctgctattc gaaaaggtct
    20881 ttataaggaa tatcatcgat tttctcataa cgacagtcat gttaagggag tgattgatgt
    20941 aagaaaccat ctcaagaaaa atcttccttt cacgggaaat attgcctaca caacgagaga
    21001 gttcacctat gataatcccc tcatgcagtt ggtccgtcac actattgaat acattaagaa
    21061 tcagaaaagc attggtcaag gggtactaga taatctctca actagtcgtg aaaacgtatc
    21121 tgaaatcgtg cgtgtaacgc cctcttataa actagctgat cgtgctaaga ttactcgggg
    21181 aaatcaatct aaacctatac gtcatgcata ctttcacgag tacagaaact tacaagaact
    21241 ttgtctgatg atcctaaacc aagaaaagca cggtttaggg tatcaagatc aaaaaatcta
    21301 tggtattctc tttgatgttg cctggctttg ggaagagtat gtttacacct tgttgccaaa
    21361 aggttttgta catcccagaa ataaggataa gacggatgga atttcagtat tttctgttgg
    21421 gaaacgaaaa gtatatccag atttttatga cagagaacga aagattgttc tagatgcaaa
    21481 atataaaaaa ctggaattga ctgaaaaagg aatcaaccgt gaggacttat tccagctgat
    21541 ttcctattct tatattttaa aagctgagaa ggctggactt gtttttccga gcaaggacaa
    21601 ggtcattgat aatgagatag gaaacctagc aggttatgga gctttgttga agaaatggtc
    21661 tatccaaatt cctcagaagt cttcatctta tagtgcattt tgtaaaatga tggaaaattc
    21721 agaagaaagt tttaaagcga ttattgatga agaagtgggg agaaaataat ttcccctctt
    21781 tcttttattt ttaacacaag aaaaatccga acaatatatt ttaattcata aaataatttg
    21841 acaaaaactg tactttggtt tataataaat taaggaaacg tcggaaaagg cgtagtgatg
    21901 cgagagcata ggtaggtcat tacaaaagaa acgagacatc gatatgttaa atgaatttcc
    21961 aatttttgat tacgaagata ttcaattgat tccaaataaa tgtgtcatta aaagccgtgc
    22021 agaagcggat acaagtgtca ctttaggaaa tcacaccttt aaactacctg ttgtgccagc
    22081 gaatatgcag acgattttgg atgaaaatgt agcagagcaa ctggctaaag gtggttactt
    22141 ctacattatg caccgttttg atgaggcagg acgcattcct tttattaaac gaatgcacaa
    22201 tcaagggctc attgcttcca tatctgtcgg tgttaaggac tatgagtatg atttcgttag
    22261 acagctcaag actgatgctc ctgagtatat cactattgat attgctcatg gtcatgcgga
    22321 tagcgtgatt tctatgattc aacacatcaa gaaagaattg ccagatacct ttgtcattgc
    22381 tggaaatgtg ggaacaccag aagctgtgcg tgaattggaa aatgctggtg cggatgctac
    22441 taaggtcgga atcggtcctg gtaaggtttg tatcaccaag gttaagactg gttttggtac
    22501 aggtggttgg cagttggctg ctctacgctg gtgtgccaag gctgcgcgta aaccgattat
    22561 cgctgatgga ggaattcgta ctcacggtga tattgccaag tctatccgct tcggtgctag
    22621 catgatcatg attggttccc tctttgcagg acatattgaa agtccaggga aaacgattga
    22681 agtcgatggt gaacagttca aagaatatta tggttcagcc tcacaatatc aaaaaggtgc
    22741 ttacaaaaat gtggaaggca aacgtatctt gcttcctgct aaaggtcatc tgcaagacac
    22801 tttaactgag atggaacaag accttcaaag tgctatttct tatgcaggtg gacgtcaggt
    22861 tgctgacctt aaacacgttg attatgtgat cgtgaaaaac tccatctgga atggggatgc
    22921 ttcccactaa gacggggtct ttgactaaaa aacttgttat tagagcaaat ttctgttata
    22981 ataaaacaag tttccaccct tagtgtaatg gatatcacgt aagattccgg ttcttgagat
    23041 gggggttcga ttccctcagg gtggatgtaa acattctaaa aagcctttaa tagggctttt
    23101 ttctttacac tactctaaat ttgccactaa aactgagaat ctctgtctaa agaattccca
    23161 aatgctttcc agtcccgttt tagagtgact cagggggctt tttttgatat aataaaaagg
    23221 actgttatca gttagaaaga ggttggtatg aaagaattac aaactgtact aaagaaccat
    23281 tttgcaatcg aatttacaga caaaaagtta ctggaaactg cctttactca tacgagttat
    23341 gccaatgagc accgcctctt aaaaatttca cataatgaac gcttggaatt tttaggagac
    23401 gctgttctac agttattgat ttcagaatat ctgtataaaa aatatcctaa aaagcctgaa
    23461 ggtgacctat caaaactccg tgctatgatt gtccgtgagg agagtttagc tggttttgcg
    23521 cgtgattgcc agtttgacca gtttatcaag ttgggtaaag gggaagaaaa atctggtggt
    23581 cgcaatcgtg acaccattct tggtgatgcc tttgaagcct ttcttggtgc ccttcttttg
    23641 gataaggatg tggccaaggt caaggaattt atctatcaag tcatgattcc taaggttgaa
    23701 gcaggcgagt ttgagatgat tacagactat aaaacccatc tccaagagtt gcttcaggtc
    23761 aatggtgatg tggctattcg ttatcaggtg atttctgaaa cagggcctgc tcacgataag
    23821 gtctttgatg tagaagttct tgttgaaggt aagagcatcg gtcaaggcca aggtcgttct
    23881 aagaaattag cagagcagga agctgccaaa aatgccgttg agaaggggct ggattcatgt
    23941 atttaaagga aatcgaaatt caggggttca agtcttttgc tgataagacc aaggtcgttt
    24001 ttgaccaagg tgtgacggca gttgttggac ccaatggatc tggaaagtcc aatattacag
    24061 aaagtctgcg ttgggctttg ggggagtcta gtgtcaagag tctccgtggg ggcaagatgc
    24121 cggatgtcat ctttgctgga acagaaagtc gcaaaccgct caattatgct tctgtagttg
    24181 tgactctgga taatcatgac ggatttatca aggatgcagg tcaagaaatc agggtggaac
    24241 gccatatcta tcgtagtgga gatagcgaat acaagattga cggcaagaaa gtccgtctgc
    24301 gtgatattca tgacctcttc ttggatactg gattgggacg agattccttc tctattattt
    24361 cccaagggaa ggttgaggag atttttaatt ccaagcctga ggaacgacga gctatttttg
    24421 aagaagctgc tggagtttta aaatacaaga ctcgcagaaa agaaaccgag agtaaactgc
    24481 agcaaactca ggataatctg gaccgcttag aggacattat ctacgagttg gataatcaaa
    24541 tcaagcctct tgagaagcaa gctgagaatg cccgtaagtt tttagacttg gaaggacaac
    24601 gtaaggctat ttatttagac gttctggttg ctcaaatcaa ggaaaataag gcagaactag
    24661 agtcgacaga agaagagttg gctcaggttc aagaactctt gatgagttat taccaaaagc
    24721 gtgaaaaatt agaagaagaa aatcaaactc ttaaaaagca acgccaagat ttacaggctg
    24781 aaatggccaa agaccaaggc agtttgatgg acttgactag tctgattagt gatttagaaa
    24841 gaaaattagc cctatcgaaa ctggagtccg agcaagtggc cctgaatcaa caggaggcac
    24901 aagctcgttt ggctgctttg gaggataaga gaaattcact cagcaaagaa aagtatgata
    24961 aagaaagctc tttagctctg ttagagggaa atctagtcca aaataatcaa aaactcaatc
    25021 gtttagaagc tgaattgctg gctttctcag acgatcctga tcagatgatt gagctcttac
    25081 gtgaacgctt tgtagctctt ttacaagaag aagcggatgt ctcaaaccag ttgacccgta
    25141 ttgagaatga gttggaaaat agtcgtcagc tttctcaaaa acaagcagat caactagaaa
    25201 agctgaaaga gcaattagct acagctaaag agaaggctag tcagcaaaaa gacgagcttg
    25261 aaactgccaa ggtgcaggtt cagaaattat tggctgacta tcaagctatt gccaaggagc
    25321 aagaggagca gaaaacttcc tatcaagctc aacaaagtca actctttgac cgtctggata
    25381 gtctcaaaaa caagcaggcc agagctcaaa gtttggaaaa tatcctgaga aatcatagta
    25441 acttttatgc aggtgttaag agtgttctcc aagaaaaaga tcgcctaggt gggattattg
    25501 gtgcagtcag tgagcatctg acctttgatg tttattatca aactgcccta gagattgcct
    25561 taggggcaag tagccagcat atcatcgtag aagatgaaga gtcggcaacc aaagctattg
    25621 atttcctcaa acgaaacaga gtcggtcgtg caacctttct tcctttgacc actattaagg
    25681 cgcgtacgat ttctagtcag aaccaagatg ctatcgctgt aagcccaggt ttccttggga
    25741 tggcagatga gttggtgact tttgatacta gactggaagc cattttcaag aacttgctag
    25801 ctacgacggc tatctttgat accgtagaac atgcgcgtga agctgctcga caagttcgtt
    25861 atcaggttcg tatggtgaca ttggatggga cagaattacg cacgggtggt tcctatgcgg
    25921 gtggtgccaa tcgccaaaat aacagtattt tcatcaagcc agaactggag caattacaaa
    25981 aagaaattgc tgcagatgaa gcaagcttgg gttcagaaga agcggctttg aagaccttgc
    26041 aagaccagat ggctgcattg acagaaagat tagaagccat caaatctcaa ggagagcagg
    26101 cacgtattca ggagcaaggc ttgtccctcg cttatcagca aactagtcag caagttgaag
    26161 aactggaaac tctttggaaa ctccaagaag aggaaataga tcgtctttct gagggagatt
    26221 ggcaagcgga taaggaaaaa tgtcaagaga gccttgctac tatcgccagt gaaaagcaaa
    26281 atctggaagc tgagattgaa gaaattaagt ctaataaaaa cgccatccaa gaacgctatc
    26341 aaaatttgca ggaagaggtg gcgcaagctc gcttgcttaa gacagaactg caagggcaaa
    26401 aacgttatga agtagctgat attgagcgtt taggcaagga attggacaat cttaatatcg
    26461 aacaagaaga aattcagcgc atgctccaag aaaaagttga caatcttgag aaggttgata
    26521 cagaattgct cagtcaacag gcggaagaat ccaaaactca gaaaacaaat ctccaacaag
    26581 gtttgattcg caagcagttt gagttggatg atatagaagg tcaactggat gatattgcca
    26641 gtcacttgga tcaagctcgc cagcagaatg aggagtggat tcgcaagcaa acacgtgctg
    26701 aagccaagaa agaaaaggtc agcgagcgct tgcgccatct acaaaatcaa ttaacagacc
    26761 agtaccagat tagctatact gaagcactag aaaaggcaca tgaattggaa aacctcaatc
    26821 tggcagagca agaggtgcag gatttagaga aggctattcg ctcattggga cctgtcaact
    26881 tggaagctat tgaccagtac gaagaagttc acaaccgtct ggactttcta aatagtcagc
    26941 gagatgatat tttgtcagcg aaaaatctgc tccttgaaac cattacagag atgaatgatg
    27001 aggtcaagga acgctttaaa tcaacctttg aagctattcg tgagtccttt aaagtgacct
    27061 tcaagcagat gtttggcgga ggtcaggcag acttgatatt gactgagggc gaccttttaa
    27121 cagctggtgt ggagatttct gttcaacctc caggtaagaa aatccagtcg cttaacctca
    27181 tgagtggtgg tgaaaaagct ctatcggctc ttgccttgct tttctccatt attcgtgtca
    27241 agaccattcc ttttgtcatc ttggatgagg tggaagctgc gctggatgaa gccaatgtta
    27301 aacgttttgg ggattacctc aaccgctttg acaaggacag ccagtttatc gttgtaaccc
    27361 accgtaaggg aaccatggca gcggctgatt ccatctatgg agtgaccatg caagaatcgg
    27421 gtgtttcaaa gattgtttca gttaagttaa aagatttaga aagtattgaa ggatgacaat
    27481 taaactagta gcaacggata tggacggaac cttcctagat gggaatggac gctttgatat
    27541 ggatcgtctc aagtctctct tggcttccta caaggaaaaa gggatttact ttgcggtggc
    27601 ttcgggtcgg ggatttctgt ctctggaaaa attatttgct gatgttcgtg atgacattat
    27661 tttcatcgcg gaaaatggca gtttggtaga gtatcaaggt caggacttgt atgaagcgac
    27721 tatgtctcgt gacttttatc tggcaacttt tgaaaagctg aaaacgtcac cttatgtaga
    27781 tatcaataaa ctgctcttga cgggtaagaa gggttcatat gttctagata cggttgatga
    27841 gacctatttg aaagtgagtc agcattataa tgaaaatatc caaaaagtag cgagtttgga
    27901 agatatcaca gatgacattt tcaaatttac aaccaacttc acagaagaaa cgctagaagc
    27961 tggtgaagct tgggttaatg aacatgtccc tggtgttaag gccatgacaa ctggctttga
    28021 atctattgat attgttctgg actatgtcga taagggtgta gctattgttg aattagctaa
    28081 aaaacttggt atcacaatgg atcaggtcat ggcttttgga gacaatctta atgacttaca
    28141 tatgatgcag gttgtgggac atcctgtagc tcctgaaaat gcacgacctg aaattttaga
    28201 attagcaaag actgtgattg gtcaccataa ggaacggtcg gttatagctt atatggaggg
    28261 cttataatgg cagatataaa attgattgca ttggacttgg acgggacctt gctgactact
    28321 gataaaaggc tgacggatcg taccaaggaa accttgaaag ctgcgcgtga tcgtggtatc
    28381 aaggtcgtat tgacaactgg tcgtccctta aaagccatgg atttctttct ccatgagtta
    28441 gggactgacg gtcaggaaga tgagtatacc attactttta atggtggatt agttcagaaa
    28501 aatacaggag aaatccttga taaaacagtc ttttcatatg atgatgtggc acgtttgtat
    28561 gaagaaacag agaaattatc actgcctctt gatgccatct cagaaggaac agtttatcaa
    28621 atccaatcgg accaagaaag tctttatgcc aaattcaatc cagctttgac ctttgttcca
    28681 gtggactttg aagacttatc tagtcaaatg acctacaaca aatgcgtgac tgcctttgct
    28741 caagaaccct tggatgcagc cattcagaag atttctccag aattgtttga ccaatatgaa
    28801 atctttaaat cacgtgaaat gttgctagaa tggtcaccaa agaatgttca taaagcaaca
    28861 ggtttggcaa aactaatcag ccatcttgga atcgaccaaa gtcaagtgat ggcttgtggt
    28921 gacgaggcca atgacctctc tatgattgaa tgggcaggtc ttggtgttgc tatgcaaaac
    28981 gctgttcctg aagtaaaggc agccgcaaat gtagtgacgc cgatgaccaa cgatgaggaa
    29041 gctgtcgcct gggctatcga agaatatgtg ctaaaggaga actaagatat gggattgttt
    29101 gaccgtctat tcggaaaaaa agaagaacct aaaatcgaag aagttgtaaa agaagctctg
    29161 gaaaatcttg atttgtctga agatgttgat cctaccttca cagaagttga ggaagtttct
    29221 caggaagaag cagaggttga aattgttgaa caagctgtgt tccaagaaga ggaaatccaa
    29281 gacacagttg aagaaagtct ggatttagag ccagttgtag aagtttctca aaaagaagtc
    29341 gaagaatttc cacactcaga agaagggaat actgagtttc tagagactat agaagaaaat
    29401 aattctgaag ttcttgaacc agaaaggcct caagcagaag aaaccgttca ggaaaaatat
    29461 gaccgcagtc ttaagaaaac tcgtacaggt ttcggtgccc gcttgaatgc cttctttgct
    29521 aacttccgct ctgttgacga agaatttttc gaggaactgg aagaactgct gattatgagt
    29581 gatgttggtg tccaagtcgc ttctaactta acggaggaac tacgttacga agccaagctt
    29641 gaaaatgcca agaaacctga tgcacttcgt cgtgtcatca ttgagaaatt ggttgagctt
    29701 tatgaaaagg atggtagcta cgatgaaagc atccacttcc aagataactt gacagttatg
    29761 ctctttgttg gtgtgaatgg tgttgggaaa acaacttcta tcggaaaact agcccaccgc
    29821 tacaaacgag ctggtaagaa ggtcatgctg gttgcagcag ataccttccg tgcgggtgca
    29881 gtagctcagc tagctgaatg gggccgacga gtagatgttc cagtagtaac tggacctgaa
    29941 aaagctgatc cagccagcgt ggtctttgat ggtatggaac gtgccgtggc tgaaggtatc
    30001 gatattctca tgattgatac tgctggtcgt ctgcaaaata aggataacct tatggctgag
    30061 ttggaaaaga ttggtcgtat tatcaaacgt gttgtgccag aagcaccaca tgaaaccttc
    30121 ttggcacttg atgcatcaac aggtcaaaat gccctagtac aggccaaaga attttcgaaa
    30181 atcacacctt taacgggaat tgttttgact aagattgatg gaactgctcg aggaggtgtg
    30241 gttctagcca ttcgtgaaga actcaatatt cctgtaaaat tgattggttt tggtgaaaaa
    30301 atcgatgata ttggagagtt taactcagaa aactttatga aaggtctctt ggaaggttta
    30361 atctaatcag aagcaaaaat cctgcaaggc ataaacttgc aggaaatttt tttattctaa
    30421 gcgaccatct tgacgatagg tgatatctgg ttgccaagtc catttggcac cgaatttttc
    30481 aagtaggtca aagctggctt gaggtcccat gcttccagct ttatagtcat gaagtggggc
    30541 accattttca gcccagagct tttcaatacg gtcaatcaac ttccatgacg cacaaacttc
    30601 atcccagtgg ctaaagttag ttgagttgtt atttaggaca tcataaatca atttttcgta
    30661 tggttctgga gaagcaccag ttgcagtcgc atctgtacgg taatcaagtg agttaggagc
    30721 caagttaaat tcttctccta cttgcttccc atttaggcta agagagaagc cttctgttgg
    30781 ttgaatatag atggtcaaaa tatttggagc aagtggttct ccaaagatag aatccatttg
    30841 tttaaagacg atgttgacat gagttccttt ttcagtcagt cgtttacctg tacggaaaaa
    30901 gaaaggaaca ccacggaatc gatcgctgtc tacaaagaag gcaccagatg taaaggtttc
    30961 agttgttgat tctggattca catttggctc gctacgataa gagatgtatt tcatgccatc
    31021 aatcttacca gagcggtatt gcccacggat aaagtgttct ttgagttctt catcagttgg
    31081 atgatagagg tttttaaaga ccttaatctt ttcagcacga atctcgtctt ttgtgaagct
    31141 tgctggtttg tccatggcga ggagcgaaag aagttgtaga gtgtggtttt ggaccatgtc
    31201 acggagggca ccggattggt catagtagcc accacgttct tctacaccca agcgctccgc
    31261 aaaggtaatt tgaacattgt cgataaaatc cttgttccaa acgttttcaa aaatcaagtt
    31321 tgcaaagcga actgcaaaga tgctttggat catttcctta ccaagataat ggtcgatacg
    31381 gaaaatttgt tcttcgtcaa atgttgctag gagttcgtca ttcaacttgt ttgcagttgc
    31441 gtaatctgta ccaaatggtt tttcaacgat caagcgctca aaacctttgc catcgacaat
    31501 gttttcagat ttgaggtgtt tggcaatggt tccaaagaac tgaggtgcca tagacaagaa
    31561 gaagagctta ttgtgttcag cttggtattt ttcattaagc tcagcttgta attgacgcaa
    31621 agcaatataa tgttccgaat cattgacatc atggctttga tagtagaagt ggctagcaaa
    31681 ttcttgggct tgctcggtac tatctgccaa atcaaggatg gactcgacaa ctacagattc
    31741 aaaatattcc ttactccaag gtctacgggc agttccaata acggcaaagt gcttggaaag
    31801 attgccggat ttatatagtc taaaaaggga agggtagagc ttgcgtttag ccaggtctcc
    31861 actcgcaccg aaaattgtaa caataacctt agatgacatc tagctaccta atttctattt
    31921 ttattcctag tcttgctagg tatgaggaaa cctcatttca taaacttaat tctaacataa
    31981 ttttccgaaa aatcaaaaat tccaatacga ggtagaaaaa ctgcaaggaa atccttacag
    32041 tttgagttta gacgtttaag accttatcta agaactcttt cagacgaggg tgttgtgggt
    32101 tatcaaagat ttggtcaggt gttccgtctt caaggaactc gccatctgca gtaaagataa
    32161 cgcggttggc aacctgacga gcaaatccca tctcatgggt tacgataatc atggtcatgc
    32221 cttgctcagc caattccttc ataacgttaa gtacgtctcc aaccatctca gggtcaaggg
    32281 cagaagttgg ttcatcgaag agcatgatgt ctggattcat tgctaggcca cgagctatgg
    32341 ccacacgttg tttttgacca cctgataggc tatctggatt ggcattagct ttatctgcta
    32401 gtccaacctt ttcaagcaac tccattccca atttctcagc ttcttcctta gtcatcaact
    32461 tgtgctcaat aggagcaaag gtgatgttgt ccaatacaga catatgaggg aagaggttga
    32521 agtgttggaa taccatgccg atattttcac ggacgtggtc aacattggtt gttttttcag
    32581 ttaaatcata gccgttcaca gtgatgtgac cgctagtgac ttcttctaaa agattgaggc
    32641 tacggaggaa agttgactta ccagaacctg aaggaccgat gatacaaaca acatctcctt
    32701 catagaactt agtcgtaatt ccttttagga cttcattttt tccatagtgc ttgtgtaaat
    32761 catttacatc aatttttaat tttgccatta acgaatcctc ttttctaagc gtttcgctag
    32821 tctagtcaaa agtgtgataa ttacaagata gaagatagca aggattgcat acatcttgaa
    32881 actttggtag ttacgagcaa tgataatctt accagtttgg aagagttcaa ccaaaccgat
    32941 agcagatacg atagttgtat ctttaagagc gataacgaat tggttgacaa agtttggcaa
    33001 catcaattta gttgcttgtg gcaagataat cttacgcatg gtttttccat aagagatacc
    33061 caagcttcgg ctggcttcca tttggccaac tggaacggcc tgaataccac cacgaacgat
    33121 ttcagcgata taagcagccg cattgagtga gagggcaatg gttccagcta caaagtcgtt
    33181 aattgggctt tgttggcctg tgatagactc gatgaagttt ggaattcccc agaagatgaa
    33241 ggctgcaaga atcatcaatg gaataccacg aataacgtca acgaaaatct cagagatgac
    33301 gcgaagagat ttgtatgggc taacgctaaa cataccgaag ataattccga tgacaatggc
    33361 aatagcaaat gagataagag ctagagcaag agtgatacca agaccgctaa ggagttgttt
    33421 gtagttgttt tgaagcaagc cccagagcgt tgtttcgtca acagtacttg ttgaagcagt
    33481 tgaagattcg ctagctaggt atttgtcaag aatcttttgg aattcaccgt ttgctttaag
    33541 gtttgcaagt ccgttgttga acatttcaat cagttctgga tttgctcctt ttttaacggc
    33601 aaaggctgtt tcaccgattg gagttccaga gattggagtt ttcaattttt gaccttggct
    33661 gatagaatat ttgagaacag gttcatcatc cataacggca tcaatggcac cagtgtttaa
    33721 actgtcatac attgaagaac catcagcaaa ggttttgatt ttgtagccgt atttgctttg
    33781 attttctgtt aggaaggttt gagaagcagt tccgttttta acaccgactg tctttccttt
    33841 tagatcttca taagaagcaa tattacttga ttctttgaca ccaagaatgg tattagcagt
    33901 gtagtatgat tctgagaagt caaaagttgc cttacgagca tctgtgacag acataccagc
    33961 gatgatacca tcggcttgac cagcttggac agcactgata gcagcatcaa aaccagggtt
    34021 ggtgatttca atttcaaaac cttggtcttt agcgattgcc ttaatcaatt ccatatcaat
    34081 accagtgtat tggttgcttg aattttggaa aacaaaaggg gcaaaagaag aatcgctggc
    34141 aatgatatat ttagccttaa caggaatagc ttttaatcct gcgagagtag ttgtagttgg
    34201 cactgctgaa gatgatgaag cagtccattt cttgataatt ttatcaagac taccatcttt
    34261 tttcatttca gacaaggctt ggttaaattc agtaaccagg tgctcgtatt tacttccttt
    34321 tttcacaccg aaagcaaaac ttcctacagc ttcaccatcc atttcaatat ggaggtcttg
    34381 accttggtta atggcatatt cgataacagg tttgtcatcc atcatggcat cgatggcacc
    34441 agcactcaag ctgttgttca ttaaatcacc agtgtcaaat gttttaatag taaagccata
    34501 tttatctttg attgtttcaa ggaaacgttg agcggcagtt ccgtttttaa caccaacggt
    34561 tttgccagtt aattggtcgt acttgctaat tttgtgtgac tttgtagtag caatgacaac
    34621 ttttgtatca tagtaagtat cagacatggt gaagactttt tcacgttctt tagtctttgt
    34681 catccctgcc atgatagcgt cggcttgccc agcttgaacc gcattgactg ctgcgtcaaa
    34741 tccaggatag gacatctgaa tgttccagcc tttaatctca gcgactttgt taataatgtc
    34801 aacatcaatt cctttataag tttgatctga atctttaaac tcaaaaggtg cataggcggt
    34861 atcagaaaca atcttaatcg tttctgcttt ggcaatacct aatgagaaaa ttgggaataa
    34921 aattagcaaa aatgctagaa attttttctt catttttagt ctccttttcc gaatattctc
    34981 tcattatatc agaaaaagta aaaaaaggca aattgttata tttttcgtgt cagaaaatat
    35041 aacattgttt tttccttttc tttcttgaat tgctattaaa aagtgctata ataatagtat
    35101 atatagaaga aaagaggacg gggatatgaa gaacaaaaga atatttaaag acttccaagc
    35161 ttcaaaaatg agtttaaaca tttacacaag ccccttgtta gcctttgttt ttgtcttcat
    35221 aggagagttt gtggctttta ctttgtatgg tattggcttg ttagctctca tcggacttgc
    35281 tagaaatttt ggagaggctg gtcaaaatct tgcaacctac ttgcagacct tgcatcagag
    35341 cttgacggat aaaacaagtg actttcgttt aattttagga ttactggcct ttggttttat
    35401 tcttaacact gtgttcagat ggacaagaaa agttgagaaa agacctattc gaaccttggg
    35461 attttataga gagaatttcc tcagcaatct tctgaaagga tttagtctag gcttggcact
    35521 ttttcttctg accttgttag gtttagtggt cttaggtcaa tatcgtttgg aatccattca
    35581 cttgaatcct tattctcttg cctttgtcgt ctttactatc ccattttgga ttttacaggg
    35641 gacagcagaa gaagtggtgg cccgtgcttg gctacttcct caattggcct caagaaccaa
    35701 tctaaaacta gctattctta tatctagcct gttctttacc ctgcttcata tgggcaattc
    35761 tggcctcacc cctctatctc tagtaaatct ctttttattc ggagttgcca tggctcttta
    35821 tcttctcaaa actgatacag tttggggtgt tgcaggtatt catggtgctt ggaattttgc
    35881 tcagggtaat ctctttggga ttttagttag tggtcaaccg tcaggaacgt ctctgatgac
    35941 ctttttacca caaggcaatc aagattggct atcaggtggt tcttttggca tagaaggttc
    36001 cattatgaca agtctggtat tactactgct gattgtctat cttgctaata aattaaagaa
    36061 agaaaatgaa aggatgtgac ttcggtccgt ccttttcttc gtgaaaatac tataagtatg
    36121 ctaaaatagg aatagcacat ggagagagga ttcttatgat caatcacatt acagataatc
    36181 aatttaaact agtatcaaaa tatcaaccat caggagatca accccaagct atcgagcagt
    36241 tggtggataa cattgagggg ggagaaaaag ctcagattct gatgggggcg actggaacag
    36301 ggaagaccta tactatgagt caggtcattt ctaaagtcaa taaaccaact ctggttattg
    36361 cccacaataa aactctggct ggtcagctct atggggagtt taaggaattt ttccctgaaa
    36421 atgcagttga gtatttcgta tcctactatg attattacca gccagaggcc tatgtccctt
    36481 ctagcgatac ctatattgag aaggatagtt ctgtcaatga cgagattgac aagcttcgcc
    36541 actcagctac ctcagccctt ttggagcgta atgatgttat tgtcgtggcc tcagtctctt
    36601 gtatctatgg tttgggttcg cccaaggaat acgctgatag tgtcgttagt ctccgtcctg
    36661 gtctagagat ttctcgtgat aaactcttga atgacttggt cgatattcag tttgaacgta
    36721 atgatattga tttccaacgc ggaagatttc gcgttcgtgg ggatgtggta gagattttcc
    36781 cagcttcccg agatgaacat gcctttcgag tagaattttt tggagacgaa attgaccgta
    36841 ttcgtgaagt tgaggctctg acaggtcagg tgttgggaga agtggatcat ttagcgattt
    36901 tcccagcgac acactttgtg accaatgacg accacatgga agttgccatt gcaaagattc
    36961 aggccgagtt ggaagaacaa ttagctgtct ttgaaaagga aggtaaactg cttgaagccc
    37021 agcgtttgaa acagcggaca gagtatgata tcgaaatgtt gcgtgagatg ggctatacca
    37081 atggggttga gaactattca cgacacatgg atggacggag cgaaggagag cctccttata
    37141 cgctcttaga tttcttccca gatgatttct taattatgat tgacgagagt cacatgacca
    37201 tggggcaaat caagggcatg tacaatggag accgttcgcg taaagaaatg ctggttaatt
    37261 atggcttccg attgccgtct gctttggaca atcgtcctct ccgtcgggag gagtttgaga
    37321 gtcacgttca tcagattgtt tacgtttcag cgacacctgg tgactatgaa aatgaacaga
    37381 ctgagacagt gattgagcaa atcattcgtc caacgggact cttggatcct gaagtggaag
    37441 tccgtccgac tatgggacag attgatgacc tcttgggtga aatcaatgcc cgcgttgaaa
    37501 aaaatgagcg tacctttatc acaactttga ccaagaaaat ggcagaggac ttgaccgact
    37561 acttcaagga aatgggtatc aaggtcaagt acatgcactc ggatatcaag accttggaac
    37621 ggacggagat tatccgtgac ctgcgcttgg gtgtctttga tgtcttggtc ggaattaacc
    37681 tgctccgtga aggaattgac gttcctgaag tgagcctcgt agctattctc gatgctgata
    37741 aggaaggttt ccttcgcaac gaacgtggac tcatccagac tattggacgt gctgctcgta
    37801 acagtgaagg ccatgtcatc atgtatgcag acacggttac ccagtctatg caacgtgcta
    37861 tcgatgaaac tgcccgccgt cggaaaattc agatgaccta taatgaagag catgatatcg
    37921 taccacagac aatcaagaaa gaaatccgtg acctgattgc cgtgaccaag gcagttgcta
    37981 aggaagagga caaggaagtc gacatcaata gcctcaacaa acaagagcgc aaggaactcg
    38041 tcaagaaact agaaaaacaa atgcaagaag ccgtcgaagt gcttgacttt gaactggcgg
    38101 ctcagattcg tgatatgatg ttggaagtca aggtcttgga ttaggggaat agtatgattt
    38161 atttaagaaa gttaaagaga gaagatttga tgtctttatg ggaaatggct tattcacaac
    38221 ttaatccagt ttggaaacag tatgatgctc cctattatga tgattatcag tatttttcaa
    38281 attttaaaga attcgaacta caaaaatcag aatccatttt aagcaactca aatcgccttg
    38341 gtatttttgt tgatgataaa ctagttggga ctgtttcgcg ttattgggta tgtaaacaaa
    38401 caagatggat ggaattggga attggtattt atgataaaaa attctggaac actggtattg
    38461 ggaaagttgc tatgttgcag tggatagata ggacgtttca ggattacttg gagttggagc
    38521 atctgggttt gacaacttgg tcagggaatc ttggtatgat gaaacttgct gaaaaattaa
    38581 gaatgaaaaa agaagctcat attccaaaag ttcgttatta tcaaggtaaa tattttgata
    38641 gtattaaata tggtattttg agagaagact gggagaaaat aaatgacggt tattatcaaa
    38701 tcaatggaaa ctcctaaaga gatagaaggt aaatcccttg ttcactggca aatgtggaga
    38761 gagtcttatg atgacctttt gcctgcggaa tttcaggata caatgacatt agaaagatgt
    38821 cgattcttta gtcaaaagta tccagaaaat acattgattg cgatggatgg cgtgaaggtg
    38881 gttggtttta tcagttatgg caattttcgt gatgagacta ttcaagctgg tgaaattatt
    38941 gctttatatg ttttaaaaga ctattatgga aaaggtatcg cacaaaagtt aatgaaagca
    39001 gctttgactg ctcttaatca tttttctgaa attttcttat gggtattgaa agataacaag
    39061 cgcgccattg ctttctatca aaaaatgggt tttacttttg atggacaaga aaaaatactt
    39121 gaacttggaa agcctataaa ggaaaaacga atggtgttct attctaaata attttaaaaa
    39181 agtaaaagat aatatctctg gtagtaagtc tgaaaattta ataaattaga aagcgagtaa
    39241 atttatgtcc cgttcccaat taacaatttt aacaaatatc tgtctgattg aagacctcga
    39301 aactcagcgc gtggtgatgc agtatcgcgc ccctgaaaac aatcgctggt ctggttatgc
    39361 ctttcctgga ggtcatgtag aaaatgatga ggcttttgcg gagtctgtca ttcgtgaaat
    39421 ctacgaagaa acagggttga ctatccaaaa tcctcaactt gtcggcatta aaaattggcc
    39481 actagataca ggtgggcgct atattgtcat ttgttataag gcgactgagt tctctggtac
    39541 ccttcaatct tcagaagagg gagaagtttc ttgggtgcaa aaagaccaga ttccaaactt
    39601 aaatctggcc tatgatatgc taccattgat ggaaatgatg gaagctcccg acaagtcaga
    39661 gtttttctac cctcgccgta cagaagacga ttgggaaaag aaaatcttct agtcttttac
    39721 taaataacct agctgatcca aggcctcctc gatatagtgg aggtcttgtt gtgtttcggc
    39781 ttcgactagg tggtaatgga tgccatctgt caattcagat agaggtctaa agtcagaatg
    39841 ctcgacttgt tctagaaaat gttgcacatc tctgcgacaa gacagtttaa gcaaggtttc
    39901 aatttctcca taaacgggat ggtcaatcaa ggtattctgg acatgcccac cattatcgac
    39961 aatagcaagg agttcctgac cgatttcttc aacttcatgt ttcactttga aaagtttgtg
    40021 aacataagga ttggtatcaa tttgcttata gatgtagcca cgattggtgg ataggatagg
    40081 agcgccatcg gctctcaaaa ttgcaatgtc ctgcacaatg acctgacgtg tgacatgaaa
    40141 atgttccgcc aaactttggc cattaagggc tttaggagct tctttcaaga gttggagcag
    40201 ggcttgtttg cgatcttttg tcatagcttt tccttttaac ggcgttttcg aagcacttta
    40261 tagacagcta gtgctaatgt atagtctacc atactatgga taattgtgcc aaatccaact
    40321 agtacaaata gaacatagaa catgttttct acattggtac ccgaagttgc gtaaaaaagg
    40381 acacaggcta atacttcagc aagggcatga acaacagcca aaacaaaatt aaaaacccag
    40441 gaagattttg gtttatctag ggtatcgggg aatttttgta ggtaaagagc tcctaaagca
    40501 ccaaaagata tatgggaaaa agcccgaaaa acgataacca tgggatagcc agccatcaaa
    40561 aatccaaaac tagaggctag gatgacaaaa actgccatca agggcgacaa gaacatggct
    40621 ataaaaatag cgatgtggct ccccaaagta taggaagcag gtggaatgac aatcttgaaa
    40681 ggcataacaa ttggaatcaa aatcgcaata gccgttaaaa gggctgtcat tgtcataaat
    40741 tgtgtctttt tccgtgtatt cacaagaatc tcctttttaa ctgcatatac actagtatgg
    40801 tacaataaac cagacaataa agcaagaatt tacttgggtt tatagatcat tttttagtta
    40861 aaagttatag tagattgaaa ctagaatagt ccacctctac ttctaaaaca ttgttagaaa
    40921 tcgatttgtc ctgttcttat ttcgttttac tatagtaaag atttcattaa aaagaaactg
    40981 tatagagcaa aatctccacc ttcaggtttg aaagcggaga ttgtttttat tttttcaagg
    41041 tttgtagtcg tggaacaatg gctagggtta gaattgcaga aatgaccaat tcagcaattg
    41101 aatttgttga gataacggtt gccagaagaa gttggatatt tccattataa acatttccaa
    41161 ataggaagaa gattcctcca aggacaaaga tagtatttgt caaggaacca agggctccag
    41221 ctaaaatcag accagtcttg tttttcatca gtttatagac taagtaagga gttaaaccaa
    41281 tcaaaatacg tgggacgatg gcaatgatag ctgagtagat gtttccgttt ggtacgaagg
    41341 gagagaagag gtagcttgtc ggtagaatcg taatcgtgtt aaccgtcaag ctaagtaatc
    41401 ccatcaaaaa tccaagtgta accccaactc gtggaccata aataatgctg gcaataatga
    41461 caggaatatg aacaatggtc ggtttgattg gaaatggaaa aaggttaaag ataagtgagc
    41521 tcagaaagtg tatcacgagc atggtagcaa aaaagatagc aatgggtgca atattagagc
    41581 gttttttcat cgatagtttc ctttattctt tctaaaataa ttgtgaggtc agctaaagct
    41641 cctcgtccgt ggtctccaca agctagtagg gattccttag gagcaatcag ctgatagccg
    41701 taggtttcta atgttttcag attattctga gttactggat ggtcatacat ttttgtattc
    41761 atagcaggag ctattagttt gggaatatga cttggtaggg ctagagctgt actggttacc
    41821 atgttgtccg caaatccgtg agctagtttt gcaatagtgt tagcagttgc aggtaccacg
    41881 ataaataaat ctgctttttt tccaagttcg atatgattga cctgatcagg atagggttcc
    41941 ttcatgacat ccaagtggac aggattctgt gagagtacct gtagtgtcaa aggttggata
    42001 aactctgtag cagcctgagt cattaagaca gtgacttgat ggccttgttt ttttagagaa
    42061 ctgactaaat ctgccgactt ataagaggcg attgaacccg ttacagccaa gagaatgttt
    42121 gccatagttt tcctttctaa gaatgatagg cttgaatttt ttcaaggagg agttctgcaa
    42181 tttcttcttt agtctggact gtttgaagct gatttttctc aacaaatata gctcggtgct
    42241 gatctgctga aatttgagtc aggtcattcg cgatgattaa atctgcttga ttcttgataa
    42301 gactttttcg tgcaatgtca accagatgat cttcggtaac atcaatcagc agtttgaaac
    42361 caatcagatg aatagtagga ttccattcct tgactaggga tatgattttg ggtgtctttt
    42421 taaggaacaa aacctgaacc tcatcagttg aagaaatctt ggcctgatga ttctgcttgc
    42481 ttaaaaattc ttttagattg gagctagcct gaacttcctc aagccctgtc atataaacag
    42541 gagtgtagtc agaaacagcc attgagtgga tcaagacctg ataatcctga acacgttctt
    42601 gcatttctat tagaaggtcc ttggtattgg taatttctcg aatacttagg ttaggatgag
    42661 gctctggctt cagagctcgt tttgtcgtaa ttaaacaaac ttcatgccct gcagaaagca
    42721 aagtctctgt gataattttc cccaagtgac ctgtagaatg gttagtgata gagcggacgc
    42781 tatcgatagc ttcactggta ccgcccgatg taactaaaat tttcatagca ctattgtaca
    42841 caaaaataag cggtaagtaa aatgaaagtg ataaattttt ggtaaaaacg aagatttact
    42901 atagtttcaa actataaagc catataaaat ttaagaaagg attctaaaag ccttaaaaac
    42961 agagatattt acgaacgttt agagagtttt aggatgttaa aaatcttgtt ttgtgatata
    43021 atgaattatc atataagagg ttagaggaat tttgaatgaa aacagatatt gaaatcgcac
    43081 agagtattga gttgaagcca attgttgatg ttgtagagaa acttggtatt tcttacgacg
    43141 atttggagtt gtacggaaag tacaaggcta aactcagctt tgataaaatt cgtgcagttg
    43201 agagcaatcc agtcggtaaa ttgatcttgg ttactgccat caacccaaca cctgcaggtg
    43261 aaggaaagtc gacgcttacc attggtcttg cggatgcctt gaacaagatt ggcaagaaaa
    43321 ccatgattgc tatccgcgaa ccgtctcttg gtccagtcat ggggatcaag ggtggtgctg
    43381 ctggtggtgg gtatgcacaa gttctgccaa tggaagacat caacctccac tttactggag
    43441 atatgcatgc tattacaact gccaacaatg ccctttctgc cttgattgac aaccacttgc
    43501 accaagggaa tgagctggga attgatcaac gtcgtatcct ctggaaacgc gttgtggact
    43561 tgaacgaccg tgcgctccgc catgtgactg ttggtcttgg tggtcctcta aacggtattc
    43621 cacgtgagga cggttttgat attacagttg cttcagaaat catggcaatt ctttgcttgg
    43681 caacggacat cgaggacttg aaacgtcgtt tggcgaatat cgttattggt tatcgctatg
    43741 accgtacgcc tgtttctgta ggtgatttgc aggttgaggg tgccttggct ttgattttga
    43801 aggatgctat taagccaaac ttggttcaga caatttacgg tacacctgcc tttgtacacg
    43861 gtggtccatt tgccaatatc gctcatggct gtaactctgt tttggcgacg acaacagccc
    43921 ttcacttggc tgattacact gttactgaag ctggttttgg tgcggacctt ggtgctgaga
    43981 aattccttga tatcaagaca ccaaacttgc caacatctcc agatgcagtt gttattgtcg
    44041 caacctttcg tgcccttaag atgaatggtg gtgtggctaa agacgctctg actgaagaaa
    44101 atgtagaggc agttcgtgca ggttttgcta acttgaaacg ccacgttgaa aatatccgta
    44161 agttcggtat tccagcagtt gtagctatta acgaatttgt atctgataca gaagctgaaa
    44221 ttgcagtctt aaaagaactc tgtgcctcaa tcgatgtacc agttgaattg gctagtgtct
    44281 gggctgatgg agcagaaggt ggagtagcac ttgccgaaac agttgttaag acaattgctg
    44341 aaaatccagc taactataaa cgtttgtatg ataatgacct ttctgtccaa gaaaagattg
    44401 aaaaaattgt cactgaaatc tatcgtggta gcaaagtgaa ctttgagaag aaatctcaaa
    44461 cacaaattgc tcaaatcgtt caaaacggtt gggacaaatt gccaatctgt atggctaaaa
    44521 ctcaatacag tttctcagac aatccaaatg cgcttggagc accagaaaac tttgaaatta
    44581 ccattcgtga attggtacca aaattaggtg caggcttcat cgttgcctta actggtgatg
    44641 ttatgaccat gccaggtctt ccaaaacgtc cagcagctct caacatggat gttgaaagcg
    44701 atggaactgt actaggcttg ttctagtgga ttgaaattga ctttaagtga gtttggaaat
    44761 aatatccaag ctcatttttt ctcagactgc aagcagttca tcaataagat ttatactctt
    44821 cgaaaatctc ttcaaactac gtcagcttca ccttgccgta ggtatatgat actgactctg
    44881 tcagttctat ccacaacctc aaaacagtgt tttg
//
LOCUS       DAVLZS010000012        44173 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLZS010000012 DAVLZS010000000
VERSION     DAVLZS010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.012"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(56..1018)
                     /locus_tag="VYO88_000690"
     CDS             complement(56..1018)
                     /locus_tag="VYO88_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1718832.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            1084..2472
                     /locus_tag="VYO88_000691"
     CDS             1084..2472
                     /locus_tag="VYO88_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1718833.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            complement(2507..2959)
                     /locus_tag="VYO88_000692"
     CDS             complement(2507..2959)
                     /locus_tag="VYO88_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1718834.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            3121..3415
                     /locus_tag="VYO88_000693"
                     /pseudo
     CDS             3121..3415
                     /locus_tag="VYO88_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3571..4785
                     /locus_tag="VYO88_000694"
     CDS             3571..4785
                     /locus_tag="VYO88_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1718835.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            4930..5064
                     /gene="rpmH"
                     /locus_tag="VYO88_000695"
     CDS             4930..5064
                     /gene="rpmH"
                     /locus_tag="VYO88_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1718836.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            5348..6247
                     /locus_tag="VYO88_000696"
     CDS             5348..6247
                     /locus_tag="VYO88_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1718837.1"
                     /translation="MVAQDPKAQDSTKLTAEKSTVKAPAQRVDVKDITHLTDEEKEKV
                     KVAILQANGLALDGATINVAGYGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATP
                     EYKLETTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESA
                     KNAIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETI
                     GVQAIAMVTVPKRLVAPNAAPKTTSAPQATAGTMQNVTYQSPAGKQLPNTGSASSAAL
                     ASLGLVVATSGFALLGRKTRRRK"
     gene            6552..7325
                     /locus_tag="VYO88_000697"
     CDS             6552..7325
                     /locus_tag="VYO88_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1718838.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            7325..7885
                     /gene="rnmV"
                     /locus_tag="VYO88_000698"
     CDS             7325..7885
                     /gene="rnmV"
                     /locus_tag="VYO88_000698"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1718839.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKSKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            7957..8856
                     /locus_tag="VYO88_000699"
     CDS             7957..8856
                     /locus_tag="VYO88_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1718840.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            9125..11155
                     /locus_tag="VYO88_000700"
     CDS             9125..11155
                     /locus_tag="VYO88_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1718841.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTEIGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            11157..11798
                     /locus_tag="VYO88_000701"
     CDS             11157..11798
                     /locus_tag="VYO88_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718842.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            11791..12084
                     /locus_tag="VYO88_000702"
     CDS             11791..12084
                     /locus_tag="VYO88_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718843.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            12335..13207
                     /gene="rsmA"
                     /locus_tag="VYO88_000703"
     CDS             12335..13207
                     /gene="rsmA"
                     /locus_tag="VYO88_000703"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1718844.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            13209..14087
                     /gene="rsgA"
                     /locus_tag="VYO88_000704"
     CDS             13209..14087
                     /gene="rsgA"
                     /locus_tag="VYO88_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1718845.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQDFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            14098..14754
                     /locus_tag="VYO88_000705"
     CDS             14098..14754
                     /locus_tag="VYO88_000705"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1718846.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRSHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            14717..15379
                     /locus_tag="VYO88_000706"
     CDS             14717..15379
                     /locus_tag="VYO88_000706"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1718847.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            15381..16637
                     /locus_tag="VYO88_000707"
     CDS             15381..16637
                     /locus_tag="VYO88_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1718848.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLYFQENEEEYED"
     gene            16627..17568
                     /locus_tag="VYO88_000708"
     CDS             16627..17568
                     /locus_tag="VYO88_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1718849.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            17835..18662
                     /gene="purR"
                     /locus_tag="VYO88_000709"
     CDS             17835..18662
                     /gene="purR"
                     /locus_tag="VYO88_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1718850.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEIGNIFDEDK"
     gene            18729..19979
                     /locus_tag="VYO88_000710"
     CDS             18729..19979
                     /locus_tag="VYO88_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1718851.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVCKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            20105..20899
                     /gene="pflA"
                     /locus_tag="VYO88_000711"
     CDS             20105..20899
                     /gene="pflA"
                     /locus_tag="VYO88_000711"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1718852.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(20974..21900)
                     /gene="yidC"
                     /locus_tag="VYO88_000712"
     CDS             complement(20974..21900)
                     /gene="yidC"
                     /locus_tag="VYO88_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1718853.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(21978..22256)
                     /locus_tag="VYO88_000713"
     CDS             complement(21978..22256)
                     /locus_tag="VYO88_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1718854.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22290..23030
                     /locus_tag="VYO88_000714"
     CDS             22290..23030
                     /locus_tag="VYO88_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1718855.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            23086..23769
                     /locus_tag="VYO88_000715"
     CDS             23086..23769
                     /locus_tag="VYO88_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1718856.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            23881..24873
                     /locus_tag="VYO88_000716"
     CDS             23881..24873
                     /locus_tag="VYO88_000716"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1718857.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTSKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            24938..25477
                     /gene="rsmD"
                     /locus_tag="VYO88_000717"
     CDS             24938..25477
                     /gene="rsmD"
                     /locus_tag="VYO88_000717"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1718858.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQITKEIGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYTKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            25467..25955
                     /gene="coaD"
                     /locus_tag="VYO88_000718"
     CDS             25467..25955
                     /gene="coaD"
                     /locus_tag="VYO88_000718"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1718859.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            25939..26976
                     /locus_tag="VYO88_000719"
     CDS             25939..26976
                     /locus_tag="VYO88_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1718860.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            27034..27264
                     /locus_tag="VYO88_000720"
     CDS             27034..27264
                     /locus_tag="VYO88_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1718861.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            27288..28571
                     /gene="murA"
                     /locus_tag="VYO88_000721"
     CDS             27288..28571
                     /gene="murA"
                     /locus_tag="VYO88_000721"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1718862.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            28564..28752
                     /locus_tag="VYO88_000722"
     CDS             28564..28752
                     /locus_tag="VYO88_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1718863.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            28791..29615
                     /gene="endA"
                     /locus_tag="VYO88_000723"
     CDS             28791..29615
                     /gene="endA"
                     /locus_tag="VYO88_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1718864.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLKWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKVTRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            29844..31175
                     /locus_tag="VYO88_000724"
     CDS             29844..31175
                     /locus_tag="VYO88_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1718865.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(31373..31443)
                     /locus_tag="VYO88_000725"
     tRNA            complement(31373..31443)
                     /locus_tag="VYO88_000725"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31409..31411),aa:Cys,seq:gca)
     gene            31859..35470
                     /gene="rpoB"
                     /locus_tag="VYO88_000726"
     CDS             31859..35470
                     /gene="rpoB"
                     /locus_tag="VYO88_000726"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1718866.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            35503..39180
                     /gene="rpoC"
                     /locus_tag="VYO88_000727"
     CDS             35503..39180
                     /gene="rpoC"
                     /locus_tag="VYO88_000727"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1718867.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            39291..39704
                     /gene="ndk"
                     /locus_tag="VYO88_000728"
     CDS             39291..39704
                     /gene="ndk"
                     /locus_tag="VYO88_000728"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1718868.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(40633..41265)
                     /locus_tag="VYO88_000729"
     CDS             complement(40633..41265)
                     /locus_tag="VYO88_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718869.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(41267..43282)
                     /locus_tag="VYO88_000730"
     CDS             complement(41267..43282)
                     /locus_tag="VYO88_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1718870.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFGALTLISQISQLRSSGIRLISGEKRWSIFLRPVGDDLKGIAVGFSLAGVLTI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNFITSTEWHDY
                     SPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            complement(43385..43681)
                     /locus_tag="VYO88_000731"
     CDS             complement(43385..43681)
                     /locus_tag="VYO88_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1718871.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPYNW
                     GAFSNYYHGSQYHWAYVGSNERDNQKTVYAGAHSAAYAFVNTNLGERITFDAGW"
BASE COUNT        12988 a         8552 c        10055 g        12578 t
ORIGIN      
        1 aaccatacat acggtaaggc gacgtgacgt ggtttgcaga gattttcgaa gagtattagc
       61 cttccatata gtctttcaaa gcctgtcctg ttagtccggc attgagggcg atgaggagtt
      121 tcaagcgagc tttttgggcg ttgagttctt taacaaagaa aacgcctgct ttttgcaact
      181 gtacgccccc accctggtag gcataaacag gctcggcaat accgttaaag catcgtgata
      241 ccagagcgac tggaattcct ttttgcagaa ggctttctaa tttttgagcc gtttctttgg
      301 gaatattacc agctccgaag gcttggataa tcaaaccgtc caagtgttct aaatccagca
      361 tatcaatcag ctcatctgtc ataccagcat aagccgagat gatagggact aaaccttgta
      421 tgtgatcaag gtcaaagcga acacgaggtt cagctgtttt gaagtagagg atttcctgtt
      481 tcatgatgag accaaggggg ccatgtgttg gagtctggaa ggtgctgaca ttagtcgtat
      541 gtgttttggt gacatacttg gcagcgtgga tttcatcgtt cataacgacc aaaactcctt
      601 tgtcagcagc cctgtcatcg ctggccactc gtaaagcact taggtaatta taaacaccat
      661 cactaccgag ttcattggag ctacgcatgg ctcctgttag aacgataggc atatggggaa
      721 cttccatggt atcaaggaaa taggctgttt cctctaaagt atcggttccg tgtgtgatca
      781 ccactccatc gtagttatct gcttcctctt taattttctg gtagaggacc agcatatgtt
      841 tgggtttgat atggggactt ggaaggttaa aaaagtccaa ggcgtggact tggattcctt
      901 caagtgggtt ggacacatgg ttcatgggat tatctgaact cgtcacaaca gcgccagaag
      961 catcggcctg catggaaata gttccacccg tatgtaaaac aaggattttc ttaggcatga
     1021 tttactcact ctttctgaaa tgtggtataa tcattgtatc acaaaagggg agattgggat
     1081 aggatggaag tcaaagctgt tttttttgat atcgatggaa ccttggtcaa caatcgcaag
     1141 agtgttttga aatccactaa ggatgcgatt aagattgtca aagaacaagg ggtactagtt
     1201 ggcgtagcga cagggcgagg accttttttt gttaaggaat tgatggacga tttggatctg
     1261 gattttgcgg taacctataa tggccagtat atctttagta aagacagagt cttgttcacg
     1321 agccctattt ccaagttaca tttgcgccat ctaattagct atgctaaaaa agagggcacg
     1381 gagattgcct tagggaccaa ggatgccatg ttgggttcta aaatcatgtc ctttggtctg
     1441 ggttcttttt cccaacgaat tagtcgcttc gttccctctg ttttaactcg gacggtgagt
     1501 cagtctttta atcgcatggt cagcaaggtt gttccccaaa aggaagagga cctgcttcac
     1561 ctgatgaatc aacctattta ccaagttttg atgctgatga caccagaaga atctgagaag
     1621 gcggcagctg attttgaaga cttgaaattg acacgtagca atccttttgc atcggatgtc
     1681 atcaatcagg gaaattctaa attagaaggc attcgccgag ttgggaaaga atatggcttt
     1741 gacctcaacc aagtcatggc ttttggtgac tcagataatg accttgaaat gctggctggc
     1801 gtcggtatgt cggtcgctat gggaaatggt agtagcagtg tcaaggaagc tgccaagcac
     1861 attaccacta gcaatcaaca agatgggatc cacaaggcct tggaacattt tggtgttttg
     1921 tcttcagaaa aagtttttgt cagccgtgac tatcatttca ataaggtcaa gaccttccac
     1981 cacatgatgg atgaacgaac ccaagaagaa cctcgagctt gggatttaga gggtgcaacc
     2041 catagggctg gttttaaaat agaagaattg gtggagtttg ttcgatcagc cagtccttct
     2101 gaagaagatt ttggtcaagc tgtatcgcaa cttcatcagg cccttgataa ggcagcaggt
     2161 aaagtagcca agaagacacc tgctcagcaa gatttgatag ggcaagtgga tgccttgatt
     2221 gacacgcttt acttcaccta cggcagtttt gtcttgatgg gggtggaccc agaacgtatt
     2281 tttgatattg tccatcaggc caatatgggg aaaatttttc cagatggcaa ggctcatttt
     2341 gatccagtga cccataaaat cttaaaacca gataattggg aagaaaaata tgctccagaa
     2401 cctgctatta aaaaggaact gcagcgccag ctcaaggctt acgaacgcca taaagagaga
     2461 aataaatcgt aaacaaaaag gagctagggg ctccttttct ttgtgattat aaggtttttt
     2521 cttgttctct cacaaccagc aaatcgacct tagcatggcg gagtatgtat tcagatgaag
     2581 agccgaccaa gaggcgttca aaggcgttga gaccagttgc gccaacgagg atgaggtcca
     2641 cttcctcggc atctggaata gtacgtgcta gcagggtctt tggatttccc atttcaatga
     2701 cgatatgaac atctgctacc ccagcatctt tagcacgttt ttcgtactct ttcatcagac
     2761 tttcagcgtc gacttggagt tcttcgtaaa cttcagcatc aaaggtggat acgctttgga
     2821 gagcgcgtgt gtcaatgaca tgtgcgatgg tgagtttagc gtcgtttcgt agagcagaat
     2881 gaactccctt gacaaaagcc aagtccgctt ccttagaacc atcgattgcg accatgatat
     2941 tttggtaacg ttgtgccata atgaaacctc ctgaaatttt cttactataa ttgtaaacct
     3001 tttcactata gaagtaaagc aaaaaaagta tttttcaaaa gaatattagg gcttaaactc
     3061 tatataaata tatgataaaa taaaagaaag gatagcagga aagaagtgaa ggaagggaga
     3121 atgatgaaaa actcttttca aaaatcaaat ttcctttatt atggaattat cctagtttca
     3181 gtcttggtag aagtgatcat gatctgtcaa ttagagagtc tggtaccgct tctttatcca
     3241 agttttattg gatttttagt ttttcatgta ctctaccatc taatcttatt tctagttgca
     3301 aaacgaagtg ggcgttggga ttacttgatg atatgggggc ttttcctcat gtttaatctt
     3361 ctttatgact cctttctagg cttgcttttt tctaggttta tcttttggta tgtgatgtgt
     3421 ctttgcaaaa tacctgctat ctctacgttc ttaacctcgc ctttagcaag gtttttcttc
     3481 tatacgaaac tagtaacaca tttcagtaaa cttgtcgcat tctctttcta gtggtataat
     3541 gttactatcc tgatgaattg aggaaacaag atgaaagaat ataacaagtc tagtaagtta
     3601 gagcatgttg cttatgatat ccgtggtccc gtattggaag aagccatgcg gatgcgagcg
     3661 aatggagaaa agattttacg tctgaataca ggaaatccag cagaatttgg ctttacagcg
     3721 ccagacgagg tcattcatga cttgattatg aatgcgcgtg atagtgaagg ctattctgac
     3781 tccaaaggga ttttctcagc ccgtaaggcc atcatgcagt attgccagct gaagaaattc
     3841 ccaaacgtag atattgatga tatttacctt ggaaatggtg tcagtgagtt gattgtcatg
     3901 tccatgcagg ggcttttgga caatggggat gaggtcttag tgccaatgcc agactatcct
     3961 ctatggacgg cggctgtcag cctagctgga ggaaatgccg ttcactatat ctgtgatgaa
     4021 gctgtggaat ggtacccaga tattgacgat atcaagtcaa aaatcacttc caataccaag
     4081 gcaattgtcc ttatcaatcc aaataaccca actggagccc tttatcctaa ggaactcttg
     4141 ctggagatta ttgagattgc ccgtcaaaac gatttgatta tctttgcgga tgaaatctat
     4201 gaccgcatgg taatggacgg acatgtgcat acgcctgtgg cgagcttggc accagatgtc
     4261 ttctgtgtca gcatgaatgg tctgtcaaaa tcccaccgca tagcaggttt ccgtgtgggt
     4321 tggatggtct tgtctggccc taagactcat gttaagggct atatcgaagg gctcaatatg
     4381 ctgtccaata tgcgcctttg ctctaacgtt ttggcccaac aagtcgtaca aacttccttg
     4441 gggggtcacc aatcagtcga tgaattgctt cttcctggtg gacgaatcta cgagcaaaga
     4501 aatttcatct ataatgccat tcaagatatt ccaggtttgt ctgccgttaa acccaaggcg
     4561 gggctctata tcttcccaaa aatcgaccgc aatatgtacc gtatcgatga tgatgagcag
     4621 tttgtccttg atttcttgaa gcaggaaaag gttctcttgg ttcatggtcg aggctttaac
     4681 tggcaggaac cagaccactt ccgtatcgtt taccttcctc gtgttgatga gttagcccaa
     4741 atccaagaaa agatgactcg tttcttgaaa cagtatcgta gatagggctt gcattcgaaa
     4801 aagctggaaa catttgccta gagctattga caaaagtgaa agaatcagat agaatagtaa
     4861 agtatgttta gtaactgatc actttatagc cggctaaacg aatacaaaat ctatgaggag
     4921 gtattcatcg tgaaacgtac ttatcaacca agtaaacttc gtcgtgcgcg caaacacgga
     4981 ttccgtaacc gtatgtcaac taaaaatggt cgtcgcgtat tggcagctcg tcgtcgtaaa
     5041 ggacgcaaag ttttggctgc ataatccaaa cgaattctat caaaaatcag taggaactcg
     5101 agtctactga tttttatttt tgtaaaaaag ttcagtagat gcaaatggat tcggaagcga
     5161 tgttacagta gattgaaact agaatagtac acctctgttt ctaaaacatt gttagaaatc
     5221 gatttgactg tcctgatcga tttgtactgt tattatttta ttttactata aagttgaagt
     5281 aggtggagat ggtacagcaa caatcgtctt taaagatggt tcagctatta caattccagg
     5341 aaatcaattg gtagcacaag atccaaaagc acaagatagc actaaactga ctgctgaaaa
     5401 atcaactgtt aaagcacctg ctcaaagagt agatgtaaaa gatataactc atttaacaga
     5461 tgaagaaaaa gaaaaagtta aggttgctat tttacaagca aatggtttag cattagacgg
     5521 agcgacaatc aatgtagctg gatatggtac agcaacaatc acattcccag atggttcagt
     5581 agtgacgatt ctaggaaaag atacagttca acaatctgcg aaaggtgaat ctgtaactca
     5641 agaagctaca ccagagtata agctagaaac tacaccaggt ggagataagg gaggcaatac
     5701 tggaagctca gatgctaatg cgaatgaagg cggtggtagc caggcgggtg gatcagctca
     5761 cacaggttca caaaactcag ctcaatcaca agcttctaag caattagcta ctgaaaaaga
     5821 atcagctaaa aatgccattg aaaaagcagc caagaacaag caggatgaaa tcaaaggcgc
     5881 accgctttct gataaagaaa aagcagaact tttagcaaga gtggaagcag aaaaacaagc
     5941 agctctcaaa gagattgaaa atgcgaaaac tatggaagat gtgaaggaag cagaaacgat
     6001 tggagtgcaa gccattgcca tggttacagt tcctaagaga ctagtggctc ctaatgctgc
     6061 tcctaagaca acaagtgcac cgcaagcaac tgcaggaaca atgcaaaatg ttacctacca
     6121 gtcacctgct ggcaaacaat tacctaacac aggttcagca tcaagtgcag cacttgctag
     6181 tcttggtcta gtggtggcaa caagtggttt tgctttgcta ggaagaaaga ctagacgtag
     6241 aaaatagaac agctagaaaa ttctattctc tacttaaagt tagattataa gggggatttt
     6301 gagaagtcat caatcctagt gatgggtgag aaaagtgaga acccaagata atcacatact
     6361 ttagctgaat aggaatattc tatcaatgta gccaatctct tctgtctcta actgtggaat
     6421 aggagatggg caatatcgga tagaaaagat agcagaatag ctctctattg aagagaggag
     6481 gggaaaccga aaaattaggt gcccctcctc ttttttggta taatagaaga tagaaaacga
     6541 ggttagaaga gatgattttt gatacacata cacacttgaa tgtagaagaa tttgcaggtc
     6601 gtgaggcaga agaaattgcc ttggctgatg agatgggtgt gacacagatg aatattgttg
     6661 gttttgataa accgacgatt gagcatgcct tggagttggt agatgagtat gagcagctct
     6721 atgcgactat tggttggcat cctacagaag ctggtactta tacagaggaa gttgaggctt
     6781 acttgttgga taagttaaaa cattccaagg ttgtggcttt aggtgaaatt ggcttagact
     6841 accattggat gacagcgccc aaagaggtgc aggagcaggt ttttcgccgt cagattcagc
     6901 tatctaagga cttggatttg ccttttgttg tccatacccg tgatgcgctg gaagatactt
     6961 atgagattat caagagtgag ggcgttggtc ctcgtggtgg tatcatgcat tcattttcag
     7021 ggacgcttga gtgggcagag aagtttgtgg atcttggtat gaccatttcc ttctcaggag
     7081 tggtgacttt caagaaggca actgacctcc aagaagcagc taaagagtta cctttggaca
     7141 agattttggt ggaaacagat gcgccttact tagcacctgt acccaagcgt ggtcgtgaaa
     7201 ataaaacagc ctatactcgc tatgtggtcg actttatcgc tgacttgcgt ggtatgacga
     7261 cagaagagct ggcggtagca acgactgcaa atgcagaacg aatttttgga ttggacagca
     7321 agtaatgaaa gagaaaattt ctcaagttat cgtggttgaa ggtcgcgatg atacggtcaa
     7381 tctcaagcgt tatttcgatg tggagaccta tgagacacga ggttctgcca tcaatgatca
     7441 ggatatagag cgaattcagc gtctacacca acgtcatgga gtcattgtct ttacagaccc
     7501 agattttaat ggggagcgga ttcggcgcat gattatgacg gccattccaa cagttcagca
     7561 tgcctttctc aagcgagatg aagctgttcc caagtccaag tccaaggggc gttctctggg
     7621 aattgagcat gccagctatg aagacctgaa aacggctcta gctcaggtga cagaacaatt
     7681 tgaacatgag agtcagtttg acattagtcg tagcgatttg attcgccttg gttttctagc
     7741 aggggcagac agccgtaagc gtagagaata tctcggagag actctccgaa tcggctattc
     7801 caacggcaag caactcctca aacgcctaga gttgtttggg gttactttgg cagaagtgga
     7861 agaagctatg aaatcttatg agtaggaaag atgtagccgt tacaattttt taagtttcac
     7921 agtatttttc gaagcaggta gaagaggagg cgtctgatat taattggtca aaaaattaaa
     7981 gagattcgga tagaaaaagg aattagtcgt ccagattttt gtggagatga gcaagaactg
     8041 acagttcgtc aactgtcgcg aattgaaagt ggagcttcgc aaccgagctt gcccaagtta
     8101 gcctatattg ctcgccggct aggagttcca gtttatagcc ttatgccgga tttttcagct
     8161 cttcctcctg cttatttaga attgaaatac cagattttac gtgaaccaat ctatggtaaa
     8221 gaagaggagt acgataagaa ggaagcgtgt ttggaagaga tttataaaac atactttgat
     8281 aatcttccta aagaagaaca attagcatgt gaagtattgc aggcgtgttt ggatacttct
     8341 agaactagaa ggcctgaata tgcagagtta atacttgagg aacatatgtc tcagatcata
     8401 gaaaaagaag tttattcaac aaatgatatg ttgttgattc gtttgttttt ttatcaaatg
     8461 ctcattagaa aagatcttgc caaatttata aatcaaatcg aaaagctaat gctctttctt
     8521 ttggaacaga aaaaggtaac taaattagaa aacttcttta taattagaga tactcttatt
     8581 tcaggaatgt gttgtcttga aaaggtagga gtaactgatt gttttaatga ttatctatcg
     8641 tgtttacaag aaattatgga taaaactcaa gattatcaaa agaaacctct tgtatttatg
     8701 tttttgtgga agcaagcatt aagagaagaa agagatttta gtttagctga atcattttat
     8761 cagtcttcta aaacatttgc gcagctaatt ggagatgaat ttctagtaaa gaaattgaca
     8821 gaggaatggc aagaggatgt caaaaaatat ttataaacat agtgaatcag tgacaaaaat
     8881 gtccttgtcc tcgtatcaaa acagttctaa agttcgtctt tagaactgtt tttttagata
     8941 taagctaaaa ataatatgaa atagttagat tttaaggaca ttgatgtcct tgatagttct
     9001 tgaaaaaacg gatataatgt atttgaagat gttgctagca gaaagaactt aataagcttc
     9061 ttaacatcgc agtgactgtg gtcaccttct cactaagtga ccaagtaact ttttggagga
     9121 aatgatgaaa cgtttattta ttttgatttc aatggtattg gtatcgcttt atatggtgat
     9181 aacttccgtt gaccatcgag aagagatttt atttggtaac tatccttctg ttgatgtgac
     9241 aggaatgatg ataaatcaac cagtagctag tcgcgaagag gtgacagagg ctttgagtca
     9301 cttggcggta gagcacaata gtctcattgc tcgtcgaatc gttgagccaa atgaagctgg
     9361 agaaacacgc tttacctatg ccacttatgg tgagggaaag cttccagaag gtctgaccat
     9421 ttcctccaag gagagtgcag aaacgagtga tttattaggg tcttacttga ttgtatcagg
     9481 aagtttggat ggagtgagct tacagaccac cttgaaagag cttggttatc aaggctttgt
     9541 ttcgaatgga gaagatccat tttcgatagt cttactattg acggccaccc ctatggtgct
     9601 actgagttta gctatttttc tgctgacctt tatgagtctg accctgattt atcggatcaa
     9661 atcccttcgt caggcaggga ttcgcttaat agctggtgag agcttgtttg gagttgctct
     9721 cagaccagtg ttagaagatg tgagacagct tatctgctca gtgctggtat ccagtctttt
     9781 gggattgggg attctctggt atcaaggtgc cttgtttatg gcaacggtgc aactggtcat
     9841 cattgctctt ctactttatg gattgaccct ggcagggatt tctaccttac taagtgtcgt
     9901 ctatctactt ggtttacagg aaaatagtct ggtggatcta ttgaaaggga aactccctct
     9961 caaacgtatg atgacattga tgatggtggg gcaactctta gctgtattgg tggtcggatc
    10021 gagtgcgaca gctctcctac cccactaccg tgaaatgcag gaaatggaga gagctagcaa
    10081 taaatggagc cagtcctcag accgttaccg tctatccttt ggttggtcta gtgcatttgc
    10141 cgatgaagaa ggaacgcgta aggataatcg tgagtggcag acatttactg aagaacggtt
    10201 agccaataca gactcttttt atattatgag caatgttgac aatttctcag atggagcaga
    10261 agtggaccta gatggcaatc gtctcagtga ctacacaccg tcagggaatg ttatctatgt
    10321 ctcaccacgc tatctgatag aagaaaagat taccgtttct tcagagttta tggacaagat
    10381 gcaaaacttg tctgagggag agtttgggct gatcttgcct gagagtttgc gagagcagtc
    10441 tgtctactac caaggattgt ttacagatta cctgcaaaac ttttcatctg aaagtgtaga
    10501 agtgacgagt cagaaacact acctcccaca ggtaaggcta gcttttacag aaataggaca
    10561 ggaacgtttc ctctataatg atgggtacaa gacaacacgc cagtacctaa aagatccgat
    10621 tattgtagtt ctaacgccgc aagcgactgg aacaagacct gttgcaggga tgttgtgggg
    10681 aactacggct aatagtgcct tgaaactaga tcgatatgga gacagcatca cagctctaaa
    10741 agagcaaggt ctgtatcaca aggtttctta cttggtaaaa agccagctat tttttgccaa
    10801 ggtactaaat gacaaacggg tggagtttta ctctctcctt attgggacga ttttgaccct
    10861 atctacggct atcttgttat ttgattccat gaatcttctc tattttgagc agttcagacg
    10921 ggagcttatg attaaacgtc ttgctggtat gacaatctat gagcttcatg gcaagtattt
    10981 actggcgcaa ggaggagttc tcttgcttgg cctagtccta tctagtattt tgacaagaga
    11041 tggtttgatt agcgctctag ttgtagcttt gtttacgctt aacgccctct tgattttagt
    11101 aaggcaggac aaaaaagaag aagctggtag catggcagta ttgaaaggaa aataagatga
    11161 ttgatattca aggattggaa aagaaattta atgaccgcgc gattttctct ggtttgaatc
    11221 tcaagctgga gaagggcaag gtttatgcct taatcggaaa gagtggaagc ggaaagacga
    11281 cgctgctgaa tatcttggga aagctagaaa agatagatgg aggaagggtt ctctatcagg
    11341 ggaaagattt aaaaaccatt cccactcgtg agtattttcg agatcagatg ggctatctct
    11401 ttcaaaattt tggcctctta gaaaaccaat caatcaaaga aaatttggat ttgggttttg
    11461 ttggtcagaa aatctcaaaa gtagaacgtt tggaaaggca agtgggggct ttagaaaaag
    11521 ttaatctagg gtatttggat ttagaacaaa aaatttatac tttatctggg ggagaggccc
    11581 aacgagttgc ccttgctaag actattttga aaaatccacc cttgattttg gcagatgaac
    11641 caacagcagc tcttgatcct gaaaattcag aggaggttat gaatctcttg gtggatttga
    11701 aagatgaaaa tcgaattatc atcattgcga cccataatcc cctagtctgg aataaggctg
    11761 atgaaatcat tgatatgagg aaacttgctc atgtgtgaaa aaatccgtat tcgcagggta
    11821 tctgattatc ctagtgccag aggtggttta gaagatatcc tcatcatgga aaatatgacc
    11881 aatcatctcc ttttggttca aatccgagtg catggctatt tgcttgattt tgctagtatt
    11941 gaagggcaaa ggcaaaagca ttatcgtttg aaaaatttac ctcagacggt tgaactgaca
    12001 gtggatgatg tggaggagga tgtggatttg accctacccg aaaatcgaag ttatcaagaa
    12061 gctgattttt ttgatactca atgaaaatca aagagcaaac taggaagcta gccgcaggct
    12121 gtacttgagt acggcaaggt gaagctgacg tggtttgaag agattttcga agagtatgaa
    12181 cgtatgtttc gagagaagcg ctaagtccct ctttaaagat ttccaagact atctttcttc
    12241 atgaggaaag atagtttttt ggtatgattt tcattcccaa aatacaaggg gaatgtgtta
    12301 caatagtagt aacagataat agaaaagaga atagatgaga attgcagatt atagcgtgac
    12361 caaggcagtg ctggagcgtc acggttttac ctttaaaaag tcctttgggc aaaatttttt
    12421 gacggatacc aatatccttc aaaaaattgt ggatacggct gaaattgatg atcaggtcaa
    12481 tgtcatcgaa atcgggccag gtattggtgc cttgacagaa tttttggctg agcgtgcagc
    12541 ccaagtcatg gcttttgaga ttgaccaccg tttggtgcca attttggcag ataccctgcg
    12601 tgattttgat aatgtgactg tagttaacga agatattctc aaggttgatt tggcgcaaca
    12661 tatccagaat tttaaaaatc ctaacctgcc aatcaaggta gtggctaatt tgccttacta
    12721 catcacgacg cctattctca tgcacttgat tgagagtggg attcctttta gtgagtttgt
    12781 ggtcatgatg cagaaagaag tagcggaccg catttcagcc cagcctaaca ccaaggctta
    12841 cggtagcttg tctatcgccg tgcagtatta catgacagcc aaggttgcct ttatcgtgcc
    12901 tcgtacggtc tttgtgccag cgccaaatgt ggattcagcc atcttgaaaa tggtgcgccg
    12961 tccagagcca gctgtagcag tggaagatga gaacttcttc tttaaggttt ccaaggctag
    13021 ttttacccat cgccgtaaga ccttgtggaa taacttgaca ggttactttg gtaagactga
    13081 agaggtcaag gacaagctga ccaaggcttt ggaccaggca ggcttgtcac caagtgtgcg
    13141 tggggaagct ctcagcttgg cagaatttgc cggtctagca gacgcactta aagggcaagg
    13201 actctaagat gcagggacaa atcattaaag ccttggcagg tttctactat gtggagagtg
    13261 atggccaggt ttatcaaaca cgcgcgcgtg ggaatttccg taaaaaaggc catacccctt
    13321 atgttgggga ctgggtggat ttctctgccg aggaaaattc agaaggctat atcctaaaaa
    13381 ttcacgaacg gaaaaacagt ctggttcgtc cgcctattgt caatatcgat caagctgtag
    13441 taatcatgtc cgtcaaggaa cctgatttta acagcaattt gctggatcgt ttcttggttc
    13501 ttttggagca caagggcatc catcccattg tctatatttc caaaatggat ttgttggaag
    13561 ataggggaga actggatttt taccagcaga cctatggtga catcggctat gactttgtga
    13621 ccagtaaaga ggaactcctg tctttgttaa caggcaaggt tacggtcttt atggggcaga
    13681 caggtgttgg gaagtcaact cttctcaata aaatcgcacc agacctcaat cttgaaacgg
    13741 gagaaatttc agacagtcta ggtcgcggtc gccataccac tcgagctgtt agtttttaca
    13801 atctcaacgg gggtaaaatc gcagatacac caggattttc atccttggac tatgaagtat
    13861 caagggctga agacctcaat caggatttcc cagagattgc tactgttagc cgagattgta
    13921 agttccgtac ttgtacccat acccatgagc cgtcttgtgc cgtcaaacca gctgttgaag
    13981 agggtgttat tgcaaccttc cgttttgaca attacctgca attccttagt gaaattgaaa
    14041 atcgtagaga aacctataaa aaagtcagca aaaaaattcc aaaataagga gaaacctatg
    14101 tctcaataca agattgctcc gtcaattctg gcagcagatt atgccaactt tgaacgtgaa
    14161 atcaaacgtc tagaagcaac tggggcagaa tatgcccata tcgatatcat ggacagtcat
    14221 tttgtaccgc aaatcagttt tggtgcaggt gtggtcgaga gccttcgttc tcatagtaag
    14281 atggttttcg attgccactt gatggtgtca aaccctgagc atcatctgga agattttgcg
    14341 cgtgcaggtg cagacatcat cagtatccat gtagaagcaa cgcctcatat tcatggcgcc
    14401 ctccaaaaaa ttcgttcact cggagttaag ccttcagtcg ttatcaatcc tggcacatca
    14461 gttgaagcca tcaagcacgt ccttcatcta gttgaccaag ttttagtcat gacggttaat
    14521 ccaggttttg gtgggcaagc ctttctgcca gaaaccatgg ataaggttcg tgagttggtt
    14581 gctcttcgtg aggaaaaagg tttgaacttt gaaatcgaag tggatggtgg gattgatgac
    14641 caaactattg cccaagctaa agaagctggt gcgaccgttt ttgtagcagg ttcctatgtc
    14701 tttaagggag atgtcaatga gcgagtacaa actctcagaa aacaactgga ctagggttgc
    14761 agtttttgca ggcggaaacc gcggtcatta tcggacagat tttgatgctt ttgttggggt
    14821 ggatcgaggc tcgctctggg tcttggaaga agacttacct cttgctctag cagtcggaga
    14881 ttttgattct gtgacggaag aagagcgaca ggtgattcaa aaacgtgccc agtattttgt
    14941 ccaagcccga ccagaaaaag atgataccga tttggaattg gctctcttaa ccatctttga
    15001 gaaaaatcct caggctcagg ttactatttt cggtgccttg ggtggccgta ttgaccatat
    15061 gttggccaat gtctttctgc ctagcaatcc taagttggca ccctatatgc atcaaataga
    15121 aattgaggat gggcaaaact tgattactta ttgtccagaa gggaccagtc agctagaacc
    15181 tcgttcagac tacgactatc tagcctttat gccagttcgg gatagccagc tgactattct
    15241 tggagccaag tatgagttga cagaggaaaa ttttttcttt aaaaaagtgt acgcttctaa
    15301 cgaatatata gatagggaag tgtcggtaac ttgcccagat ggttatgtgg tcgtactgca
    15361 tagcaaggat aggaggtagg atggaaagtt tacttattct attattaatt gccaacctag
    15421 ctggtctctt tctgatttgg caaaggcagg ataggcagga gaaacactta agtaagagct
    15481 tggaggatca ggcagatcat ttgtcagacc agttggatta ccgctttgac caagccagac
    15541 aagccagcca gttagaccaa aaagatttgg aagtggctgt cagcgaccgt ttgcaagaag
    15601 tgcggattga attgcaccaa ggcctgaccc aagtccgtca agaaatgaca gataatctcc
    15661 tccaaactag agataagaca gaccaacgtc tccaagcctt gcaggaatca aatgagcaac
    15721 gtttggaaca aatgcgccag acggtcgagg aaaaactaga aaagaccttg cagacacgct
    15781 tacaggcttc ctttgagaca gtttctaaac aactggagtc tgtcaatcgt ggtcttggag
    15841 aaatgcagac agttgcccgt gatgtcggag ctcttaacaa ggttctctct ggaaccaaga
    15901 cgcgagggat tctgggagaa ttgcaactgg ggcaaattat tgaagacatc atgacacctg
    15961 cccagtacga acgagaatac gcaacggttg aaaactctag tgaacgagtg gagtatgcca
    16021 tcaagttacc cggacaaggc gaccaagaat acgtctatct tccaattgac tctaagtttc
    16081 cactggcaga ttattaccgc ttggaagaag cctatgagac aggtgacaag gatgagattg
    16141 aacgctgtcg taagtcactc ctagcaagcg tcaagcgctt tgccaaggat atcaagagca
    16201 agtacatagc accgcctcgg acaaccaact ttggaatctt gtttgttccg acagaaggtc
    16261 tttattcaga gattgtgcgc aatccggtct tctttgatga tttgagacgg gaagaacaga
    16321 ttattgttgc aggaccaagt accctatcag cccttcttaa ctccctatca gttggtttca
    16381 agacccttaa tatccaaaag agtgccgacc atatcagcaa gactcttgcc agtgtcaaga
    16441 ccgagtttgg caagtttggt ggtattctgg tcaaggcaca aaaacatctc caacatgcct
    16501 ctggcaatat tgatgaatta ttaaaccgtc gtaccatagc tatcgagcgg acgctccgtc
    16561 acattgagtt gtcagaaggt gagcctgcgc ttgatctact ctattttcaa gaaaatgagg
    16621 aagaatatga agattagtca catgaaaaaa gatgagttat ttgaaggctt ttacctaatc
    16681 aaatcagctg acctgaggca aactcgagct gggaaaaact acctagcctt taccttccaa
    16741 gatgatagtg gcgagattga tgggaagctc tgggatgccc aacctcataa cattgaggcc
    16801 tttaccgcag gtaaggttgt ccacatgaaa ggacgccgag aagtttataa caatacccct
    16861 caagtcaatc aaattactct ccgcctgcct caagctggtg aacccaatga cccagctgat
    16921 ttcaaggtca agtcaccagt tgatgtcaag gaaattcgtg actacatgtc gcaaatgatt
    16981 ttcaaaattg aaaatcctgt ctggcaacgg attgtccgaa atctctacac caagtatgat
    17041 aaggaattct actcctatcc agccgccaag accaaccacc atgcctttga aacgggcttg
    17101 gcttatcata cggcgaccat ggtacgtttg gcagacgcta ttagcgaagt ttatcctcag
    17161 ctcaataaga gcttactcta tgcggggatt atgctgcatg acttagctaa ggttatcgag
    17221 ttgacggggc cagaccagac agagtacaca gtgcgaggta atcttcttgg acatatcgct
    17281 ctcattgata gcgaaattac caagacagtt atggaactcg gcatcgatga taccaaggaa
    17341 gaagtcgttt tgcttcgtca tgtcatcctc agtcaccacg gcttgcttga atatggaagt
    17401 ccagtccgtc cacgtattat ggaggcagag attatccata tgattgacaa tctggatgca
    17461 agcatgatga tgatgtcaac agctctggct ttggtggata aaggagagat gtccaataaa
    17521 atcttcgcta tggataatcg ttccttctat aaaccagatt tagattgata atttaagaaa
    17581 aatgagcatt ttttaggata agaatgttcg tttttttatg tgaatatggt ataataagta
    17641 aaagacaaaa atgaatactc ttcgaaaatc tcttcaaact agggtagtat cgccttgtcg
    17701 tatgtatata tgcaggtata ttacagggtt tgtcagttct atcgacaatc tcaaagcagt
    17761 gttttgaacc accagcgacc agctttctag tttgcttttt gattttttga ataaaaatgg
    17821 aataggaaat agaaatgaaa ttaagaagaa gtgatcggat ggttgtcatt tccaactatt
    17881 tgattaataa tccttataaa ctaactagtc tcaatacttt tgctgaaaag tatgagtctg
    17941 ctaaatcatc catctcagaa gatatcgtca ttatcaaacg cgcctttgag gaaattgaaa
    18001 tcggtcatat ccagacagtg actggggctg gcggaggtgt catcttcaca ccgtctattt
    18061 cgagtcagga tgctaaggaa atggttgaag acttgcgtac caagttgtca gaaagtgacc
    18121 gtatcttgcc aggtggttat atctatctgt ctgatttgct tagcacacca gccatcttga
    18181 aaaatattgg tcgtattatt gccaaaagct ttatggacca aaaaattgac gcggttatga
    18241 ccgtagcaac taagggtgtg ccacttgcaa atgcagttgc caatgtcctc aatgtctctt
    18301 ttgtcattgt gcgccgtgac ctgaaaatta ccgaaggttc aactgttagc gtcaactatg
    18361 tttcaggttc aagtggtgac cgtatcgaga aaatgttcct ttcaaaacgt agtcttaagg
    18421 caggtagccg tgtcttgatt gtggatgact tcttgaaagg tggcggaacg gtcaatggta
    18481 tgattagtct cttgcgcgag ttcgactcag aactggcagg tgtagcggtc tttgcggaca
    18541 atgcccaaga agaacgtgaa aagcagtttg actacaagtc actcttgaag gtaactaata
    18601 ttgatgtcaa gaaccaagcc atcgatgttg agattggcaa tatctttgac gaagataaat
    18661 aagagataga actaaaggtt ggaacgattg tcccagcctt tctttgcaaa cagaatagaa
    18721 ggaagcttat gaaaacacca tttatcaata gagaagagtt agaagcgatt gttgccgagt
    18781 tcccgactcc ctttcacttg tatgatgaga aggggattcg tgagaaggca agagctgtca
    18841 accaagcttt ttcgtggaac aagggcttta aggaatattt tgcagttaag gctactccaa
    18901 ctccagctat tttgaaaatt ctccaagaag aaggttgtgg tgtggactgc tctagttatg
    18961 tagagctttt gatgagccat aaactggact ttctgggttc tgagattatg ttctcttcca
    19021 acaacacgcc agacaaggaa tacgcctatg cacgtgaatt gggtgcgacc attaacttgg
    19081 atgcctttga agatattgaa catctggaga gagtagcagg cattccagaa atcatctctt
    19141 gtcgttataa tcctggaggc gtttttgaac tggggacaga cattatggac aatcctgggg
    19201 aggctaagtt tggcatgacc aaggaccagc tctttgaagc ctttgctatc ttgaaggaaa
    19261 aaggagccaa gacttttggg cttcactcct tcctagcgtc caataccgtg acccatctct
    19321 attatccaga gttggctcgt cagctctttg aactggctgt tgaaatcaag gaaaagttgg
    19381 gcatttcgtt agactttatc aatctttctg gcggtattgg tgttaattat cgtccagacc
    19441 aggagccgaa cgatatcgcc ttgattggtg agggagtttg taaggtgtat gaagaagttc
    19501 ttacgtcagc aggtcttggt caggtcaaga ttttcaccga attgggtcgt tttatgctgg
    19561 cacctcacgg tgctctagtc acaagagtca ctcataagaa ggaaacctac cgtacctatc
    19621 taggtgtaga tgcctcagca gtcaacctca tgcgtccagc tatgtacgga gcttaccatc
    19681 atattagcaa cgtgacccat ccagatggac cagctgaagc ggtagatgtg gttggttcac
    19741 tctgtgaaaa caatgataaa tttgcagtca atcgcgaact gcctcataca gaaatcggtg
    19801 atttgctggt aattcatgat acaggtgccc acggattttc aatgggctac cagtataatg
    19861 ccaaattacg ttctgcggaa atcctctata ccgaagaagg taaagcccgt caaatccgcc
    19921 gtgcagagcg ccctgaggac tattttgcaa ccttatatgg cttcgatttt gaagaataat
    19981 ctgataatag attgaaaatg aaattgaaaa acagattgct ttctaaaaaa taggcaaaaa
    20041 tcttgttttt cctttaagtc gtgatataat aaaactataa aacgttttca aggaaggtaa
    20101 cgatatgtct gaagaaacaa ttgattatgg acaagtgaca ggaatggtgc attcgacaga
    20161 aagctttggg tcagtagatg ggcccggtat tcgctttatt gtctttttgc agggctgtca
    20221 catgcgttgc cagtattgcc acaacccaga cacttgggct atggagtcca ataagtcacg
    20281 tgaacggacg gtagatgatg tcttgacaga ggccttgcgc taccgtggtt tctggggaaa
    20341 taagggtggg attacagtca gtggaggaga agctctcttg cagattgatt tcctgattgc
    20401 cctcttcacc aaggctaagg aacaaggaat ccactgtacc ttggatacct gtgctcttcc
    20461 tttccgtaat aaaccacgtt accttgagaa gtttgacaaa ctcatggctg tcactgactt
    20521 ggttcttttg gatatcaagg aaatcaacga agaacagcac aagattgtca ctagccaaac
    20581 taataaaaat atcttggctt gtgcccagta tctatcagat attggaaaac ctgtctggat
    20641 tcgccacgtg ctagttccag gattgacaga cagagatgat gacttgattg aacttggtaa
    20701 gttcgtcaag accctcaaaa atgttgataa gtttgaaatt ctaccttatc acaccatggg
    20761 tgagttcaag tggcgtgaac ttggaattcc atattccctc gaaggagtca aaccaccaac
    20821 agcagatcgc gtcaagaacg ctaaaaaact catggatact gaaagttatc aagattatat
    20881 gaaacgtgta catggataga aaagaagcct gatggaaaca tcgggctttt gatttgtaaa
    20941 aagacttagc aaatcagcta agcctttttc ttcttatctc gaacgttgtt ttccagcgtt
    21001 gcgatttttg tgttttttct tgcttgtgat agcagttggt tgttcagggg taacgtcttt
    21061 tcgtccactt ggtttagaga aagcacttgc ttttggtggg ttcttggcta gttcttcacg
    21121 gacttttttg cgaagttttg gacgaacgat atagttgacg ataaactgtt ggagaatcat
    21181 catgaaacca ccgacaaccc agtaaagtgt gacactagct ggtgagaaga gggagaagac
    21241 gacgatcatg agtgggctca tgtaaatcat tttcttgatt tgttctcttt gcatttcatc
    21301 ttctactccg tgaagtgaaa ggagcgattg aagatagtaa aggacaccag cacaggcaac
    21361 caaaatcata cttggagaac ctagaggaat gcctaggtag cttgcttgag caaccccttc
    21421 agtatgttgg gcagcaaagt agatagcaga gaagaaaggc atttgaagga ggatagggaa
    21481 acatcctaca ccaccaaaca tgctgatgcc gtgctctttt tgagcggcaa agagggcttg
    21541 ttgggcttcg agtttttctt cttgagtagt tgcttctttg agacgtgttt ggtgtggctc
    21601 aaggacatgc ttgagagcgt tcatcttttc agagtgaagc gttgccttcc atgattggta
    21661 gataccaagt ggtaagataa tcaagcgtac gataatggtt acgataatga tagcgacacc
    21721 aaagcctaga cctttatcag tagcgaagta cttgatagct tcagccatag gcgctccgat
    21781 cgtattccaa ataaatcctg ttggctgacc tgtggtttta tcgacattga cacagccagt
    21841 caagacaagc aacatagcca ctcccatagc cgagaatgca aaacgtttaa tagatttcac
    21901 tgtttttatt ccttctttaa aaattatacc tttctattct actgtttttt tacaaaatat
    21961 acaatagttc tggagaccta atttgcgatt ttaaagtcag agtagggagg aaagttgctt
    22021 agtttgacat ctaagtagct tacttttgaa aaaggtgtcg gtccttttcg gatttcttgg
    22081 ataaattttg ccatgatagc agatgagtct gcttgggcta agatttccac tgtgccatcg
    22141 tcgttattcc atactcgacc tgtgatacca ccaatttcaa gtgccaagct gtaaacaccc
    22201 caacgaaagc cgactccctg taccctacct tgggcaatca ttctaacctt ttgcatacca
    22261 aacccctttg attgtgttat aatatttcta tgactattat aacctcaaaa gccaattctg
    22321 tggtaaaaaa tgccaagaaa ttacgccaaa aaaaataccg caagtctgcc tatttgattg
    22381 aaggctggca cttgtttgaa gaagctgtcc aagctggagt gacgattgag aaaatctttg
    22441 ccctagaaaa ttatcgagat cagttagcta ctttttcgca aactgtctgg gtgtcagagg
    22501 atattttgct agatttggcg gattctcaga ctccacaggg aattgttgcc gtggttcaaa
    22561 aagaagaagt aggacaagct gatttgagtc agggcaagtt cttgtttttg gaagatgtgc
    22621 aagatcctgg taatgtagga actatcattc gaactgcgga tgcagcaggt tttacaggag
    22681 tgattgtttc agataagtcg gcagacatct acagtctcaa aaccctacgt tccatgcaag
    22741 gtagtcattt ccatctgccc atttaccgga tgactagtca agcgcttctt gacgaaacta
    22801 aaaaggtagc tatcccagtg ctagcaacaa ccctatctaa agattctgtt gattacagag
    22861 aactgccttc tatagaaaat tttgtactag ttatgggaaa tgagggtcaa ggaattagtc
    22921 cccttatggc tgaaagtgca gaccagttgg tccatattag catgaagggg caggccgaga
    22981 gtttgaatgt tgcagttgca gccggtattt taatcttcca tttaagctaa ttttaacttt
    23041 ttttgttata atcaaggaaa gatgttcaca gaaaaggaga aaaggatgaa tcacactatt
    23101 atacatgacc gtgcaggtct caatcaattt tacgctaagg tttatgcctt tgttggtctg
    23161 ggaatcggac tatctgcttt ggtatcaggc cttatgttga cggtctttca gtctcagttg
    23221 gtttacttgt tgatgcaggg gcgtctctgg ttgaccattg ctacttttgc ggagttggct
    23281 ttggttttcg ttgccagtag catggcttca agaaatagtc cagctgctct tccagtattt
    23341 ttactttact ccgttttaaa cggctttacc cttagttttg tggtggcttt ctatactccg
    23401 ggtacagttt tatctgcctt tgtatcgagc gcccttctct tctttgtcat ggcggcagtt
    23461 ggtatcttta ccaagaaaga cttgagtggg attggtcgag caatgatggc agctctcatt
    23521 ggtttactga ttgctatggt agtcaatatt ttcttggcta gtggcttctt tgattatatg
    23581 attagcgtag ccatggtttt ggttttttca gggttgattg cttgggataa ccaaaagatt
    23641 cgcctcgcct atgaacaatc acaaggtcgt gtagcgacag gctgggtggt gtcaatggct
    23701 ctcagcatct atcttgattt tatcaatctt ttcctaagta ttctacgtat ctttggtcgc
    23761 aatgactaaa aggtctatga aatcagtgtt ttgagtgaca ctgatttttt ttaaattttc
    23821 tcttttcttt tcttggaaat aggtgtataa tacgtttatt aaatttttga ggagttgtct
    23881 atgaagaaaa gttttatcca tcaacaagaa gaaatttcct ttgtcaaaaa cacttttacc
    23941 cagtatttga aagataagct agaagttgtc gaagttcaag gtcctatctt gagtaaggtc
    24001 ggtgacggaa tgcaggacaa cctgtctggt gtggaaaatc cagtatcggt caaggttctc
    24061 caaatccctg atgctactta tgaagtggtg cactcacttg ctaaatggaa acgccacacc
    24121 ttggctcgtt ttggctttgg tgaaggagag ggtctctttg tccacatgaa agcccttcgt
    24181 ccagatgagg attccttgga tgcaacccac tctgtttatg ttgaccagtg ggactgggag
    24241 aaggttatcc caaatggtaa gcgtaacatc gtttatctaa aagaaacagt tgagaagatt
    24301 tataaggcta ttcgcctgac tgagctagct gttgaagctc gctatgacat cgagtctatc
    24361 ttgccaaaac aaatcacctt tatccataca gaagaattgg tagaacgcta tccagacttg
    24421 acatcgaaag aacgtgaaaa tgcgatttgt aaagaatttg gagccgtctt tttgattggt
    24481 atcggtggcg agttgccaga tggtaaaccg cacgatggac gtgcaccaga ctatgatgac
    24541 tggacaagcg agtctgagaa tggctacaag ggtctaaatg gtgatattct tgtctggaat
    24601 gagtctttag gtggagcctt tgagttgtct tctatgggaa ttcgtgtaga tgaagaaact
    24661 cttagacgtc aggtggaaat tacaggtgat gaagaccgct tggaattgga atggcacaag
    24721 tctttgttga atggtctatt cccattgaca atcggtggag gaattggaca atctcgtatg
    24781 gccatgttcc tacttcgcaa gagacacatc ggagaagtgc aaacaagtgt ttggcctcaa
    24841 gaagtccgcg atacttacga aaatattttg tagagaatcg aaccgcaagg ttcggttttc
    24901 tttctctttt tgtctataat ttggtataat aaacagtatg aaaatcgtat caggaatcta
    24961 tgggggacgt cccctcaaga cactagaagg caagacgaca agacctactt cggataaggt
    25021 taggggagcc atttttaaca tgattggtcc ctactttgaa gggggacgag tcttggacct
    25081 ttatgcaggt agtggtggtt tatctatcga agcagtatcg cgtggcatgt ccagtgctgt
    25141 tttggtggag cgagaccgta aggctcagac catcgtggct gaaaatatcc agataaccaa
    25201 ggaaattgga aaatttcaac tcctcaagat ggatgcagaa agggcattgg aacaggtatc
    25261 tggggaattt gacctcgttt tcttagaccc tccctatacc aaggaacaaa tcgtagcaga
    25321 tattgaaaaa atggctgaga gagagctttt ttctgaagat gttatggttg tgtgcgagac
    25381 ggataaggcc gttgaacttc cagaagaaat tgcctgtctg ggtatctgga aggaaaagat
    25441 ttatggaatt agtaaggtga cagtctatgt cagataagat tggcttattc acaggctcat
    25501 ttgatccgat gacaaatggg catctggata tcattgaacg ggcgagcaga ctctttgata
    25561 agctctatgt cggtattttt tttaatcccc acaaacaagg atttcttcct atcgaaaatc
    25621 gtaaacgggg gctagaaaag gctttgggac atctggaaaa tgttgaagtc gtggcttctc
    25681 atgatgaatt ggtggtcgat gttgcaaaaa gattgggtgc tacttgtcta gtgcgtggtt
    25741 tgaggaatgc ggcggatttg caatatgaag ctagttttga ttactacaat catcagctgt
    25801 cttctgatat agagactatt tatttacata gtcgacctga acatctctat atcagttcat
    25861 caggcgttag agagcttttg aagtttggtc aggatattgc ctgctatgtt cccgagagta
    25921 ttttggagga aataagaaat gaaaaaaaag attagatggc ccttatacgt cattgcggcc
    25981 ttgattgtga ctttcttggc atttgtagtg cccttgcctt attatataga ggttccaggt
    26041 ggttcggaag atattcgcca agtccttaaa ataaatgaca cagaagataa ggaagctggt
    26101 gcctatcaat tcgttacggt tggtgttcaa catgccactt tagctcatat gatttatgct
    26161 tggttgacac cttttacaga tattcgtagt gctcaggaga ctacaggtgg ttcttccgat
    26221 gttgaattta tgcgaatcaa tcaattctac atgcaaacat cgcaaaatat ggccaagtat
    26281 caaggactaa aaacagctgg taaggatatc gaactcaagt actttggagt ttatgttttg
    26341 aatgtgacgg ataattcaac ctttaaaggg attctcaata tctctgatac agtcacagca
    26401 gtcaatgatc agacctttga tagttccaaa gacttgattg attacgtcag ttctcaaaaa
    26461 ttaggggatt ccgtcaaggt cacctatgaa gaggatgggc aaaccaagtc tgcagaagga
    26521 aagattatca ccttggaaaa tggcaaaaat ggaattggaa tcggcttgat tgaccgtaca
    26581 gaggtaatca gcaatgtccc aattagcttt tcaacagctg gtattggcgg tccaagtgct
    26641 ggtctcatgt ttagtctagc tatctatact caaatagctc acccagatct tcgtaatggt
    26701 cgtattgttg ccggtacagg taccattgac cgcgatggta atgtgggaga cattggaggt
    26761 attgataaga aggttgtagc ttcggctagg gcaggtgctg ctattttctt tgctcctgat
    26821 aaccctgtta gcgaagaaga acaaaaggcg catccggacg cgaaaaacaa ctaccaaaca
    26881 gccctagaag cggctaaaac aatcaagacg gatatgaaaa tcgtgcccgt taaaacccta
    26941 caagatgcga ttgattactt gaaaaacaat ccctaatttt tgagtgaagt ttccaaacta
    27001 gcgcacaaac agagaagatg gtataatagt caaatggttc aattattatt cactctaagt
    27061 agtcatatgc tctttattta tgtgagtttt taccttttaa aggatcttgt tagatgggag
    27121 aaggttttaa aagtgacaga tgagaataca agaaaagttc gtttattagt agcctttttt
    27181 agcattgtca taggctacat cctgagttct ttctttatta gcctgtatca tttgtggcaa
    27241 gaagcgctta gaggattatt atgaaatcaa gagtaaagga aacgagtatg gataaaattg
    27301 tggttcaagg tggcgataat cgtctggtag gaagcgtgac gatcgaggga gcaaaaaatg
    27361 cagtcttacc cttgttggca gcgactattc tagcaagtga aggaaagacc gtcttgcaga
    27421 atgttccgat tttgtcggat gtctttatta tgaatcaggt agttggtggt ttgaatgcca
    27481 aggttgactt tgatgaggaa gctcatcttg tcaaggtgga tgctactggc gacatcactg
    27541 aggaagcccc ttacaagtat gtcagcaaga tgcgcgcctc catcgttgta ttagggccaa
    27601 tccttgcccg tgtgggtcat gccaaggtat ccatgccagg tggttgtacg attggtagcc
    27661 gtcctattga tcttcatttg aaaggtctgg aagctatggg ggttaagatt agtcagacag
    27721 ctggttacat cgaagccaag gcagaacgct tgcatggtgc tcatatctat atggactttc
    27781 caagtgttgg tgcaacgcag aacttgatga tggcagcgac tctggctgat ggggtgacag
    27841 tgattgagaa tgctgcgcgt gagcctgaga ttgttgactt agccattctc cttaatgaaa
    27901 tgggagccaa ggtcaaaggt gctggtacag agactataac cattactggt gttgagaaac
    27961 ttcatggtac gactcacaat gtagtccaag accgtatcga agcaggaacc tttatggtag
    28021 ctgctgccat gactggtggt gatgtcttga ttcgagacgc tgtctgggag cacaaccgtc
    28081 ccttgattgc caagttactt gaaatgggtg ttgaagtaat tgaagaagac gaaggaattc
    28141 gtgttcgttc tcaactagaa aatctaaaag ctgttcatgt gaaaaccttg ccccacccag
    28201 gatttccaac agatatgcag gctcaattta cagccttgat gacagttgca aaaggcgaat
    28261 caaccatggt ggagacagtt ttcgaaaatc gtttccaaca cctagaagag atgcgccgca
    28321 tgggcttgca ttctgagatt atccgtgata cagctcgtat tgttggtgga cagcctttgc
    28381 agggagcaga agttctttca actgaccttc gtgccagtgc agccttgatt ttgacaggtt
    28441 tggtagcaca gggagaaact gtggtcggta aattggttca cttggataga ggttactacg
    28501 gtttccatga gaagttggcg cagctaggtg ctaagattca gcggattgag gcaagtgatg
    28561 aagatgaata agaaatcaag ctacgtagtc aagcgtttac ttttagtcat catagtactg
    28621 attttaggta ctctggctct aggaatcggt ttaatggtag gttatggaat cttgggcaag
    28681 ggtcaagatc catgggctat cctgtctcca gcaaaatggc aggaattgat tcataaattt
    28741 acaggaaatt aggctggaga accagccttt ttctaaagat aaggagaaat atgaacaaaa
    28801 aaacaagaca gacactaatc ggactgctag tgttattgct tttgtctaca gggagctatt
    28861 atatcaagca gatgccgtcg gcacctaata gtcccaaaac caatcttagt cagaaaaaac
    28921 aagcgtctga agctcctagt caagcattgg cagagagtgt cttaacagac gcagtcaaga
    28981 gtcaaataaa ggggagtctg aagtggaatg gctcaggtgc ttttatcgtc aatggtaata
    29041 aaacaaatct agatgccaag gtttcaagta agccctacgc tgacaataaa acaaagacag
    29101 tgggcaagga aactgttcca accgtagcta atgccctctt gtctaaggtc actcgtcagt
    29161 acaagaatcg taaagaaact gggaatggtt caacttcttg gactcctcca ggttggcatc
    29221 aggtcaagaa tctaaagggc tcttataccc atgcagtcga tagaggtcat ttgttaggct
    29281 atgccttaat cggtggtttg gatggttttg atgcctcaac aagcaatcct aaaaacattg
    29341 ctgttcagac agcctgggca aatcaggcac aagccgagta ttcgactggt caaaactact
    29401 atgaaagcaa ggtgcgtaaa gccttggacc aaaacaagcg tgtccgttac cgtgtaaccc
    29461 tttactacgc ttcaaacgag gatttagttc cctcagcttc acagattgaa gccaagtctt
    29521 cggatggaga attggaattc aatgttctag ttcccaatgt tcaaaaggga cttcaactgg
    29581 attaccgaac tggagaagta actgtaactc agtaaaagat aagcctaaac tcctatgtca
    29641 cttatggatg taggagttct ttttactagt ttaagcaggg ctagaacagg tactaagaaa
    29701 aaatagcaac ttctaaaact aacttccagt tttgggagag agatggaagt tactttgaga
    29761 agttacggta agaaaaaata atatgtattg gattaaattt tgtgatataa taaaggataa
    29821 gatactattt taggagaaga actatggaag acccaagtag tcagaatttg ttgctacaat
    29881 ttgttttatt gtttatcttg acggtattaa atgccttttt ctcagccaca gaaatggcca
    29941 tggtttctct taatcgtgcc cgagttgaac aaaaggcgga agaaggagac agacgctaca
    30001 tccgcctgct gaaggtacta gaaaatccta accacttttt atcaaccatt caggtaggaa
    30061 tcaccctgat tacaatctta tcaggggcga gtttaactaa tactctagga cgtgtgattg
    30121 cctcttggct tgggaatggc gaaacagcac aagccgtggc aacttttcta tccttggcat
    30181 ttttgaccta tatttccatc gtttttgggg aattatatcc taagagaatc gctcttaatc
    30241 taaaggatgc cttggcaatt cgtacagcgc cgattatcat tgggatcgga aaactagtca
    30301 gtccttttgt ttggctttta gctgcttcga ccaatttctt gagccatttg actcctatgt
    30361 cattcgatga tgcggatgaa aagatgaccc gtgatgaaat tgcctatatg ctgacaaata
    30421 gtgaagaaac attggatgct gatgagattg agatgctaca aggtgtcttt tcgctcgatg
    30481 aactgatggc acgagaggtt atggtgcctc gaacggatgc ctttatggtg gatattcagg
    30541 atgatagtca agccattatc caaagtattt taaaacaaaa ttattctcgt atcccggttt
    30601 atgatgggga taaggacaat gtaattggaa tcattcacac caagagtctc cttaaggcag
    30661 gctttgtgga cggttttgac aatattgttt ggaagagaat tttacaagat ccactttttg
    30721 tacctgaaac tatttttgtg gatgacttgc taaaagaact gcgaaatacc caaagacaaa
    30781 tggcaatctt gctggatgaa tacggtggta tggctggttt ggtgactttg gaagacctct
    30841 tagaggaaat tgttggtgaa attgatgatg aaacggacaa agcagcaata gatgttcatc
    30901 agattggcga ggatacctac attgttcaag gaactatgac cctcaatgat ttcaataatt
    30961 actttaatgt tgaactggaa agtgatgacg ttgatactat cgctggttat tatttgacag
    31021 gagtgggaac cattccaacg actgagaaac tcagctatga attggtcagc caaaacaaac
    31081 agtttatctt aaccaatgat aaagtgaaga atggacgtgt taccaaggta aaagtccaaa
    31141 tcacagaagt cgaaatagaa gaagaaacag aataaactag aggcttttgt caccaggcgt
    31201 gacgaagctt ttttcaattg atttcaaaag ggaattatgc catggaaaga actctgccac
    31261 aaactcgctc caaaagtttt taaagttata cgtatttatt cgagggaaaa taagaaaagc
    31321 ccttcaaatt gggctttctg ttcatttgaa acctgataaa tcaagttata gaaggcggta
    31381 gacggatttg aaccgacgat caagcttttg cagagccgtg ccttaccact tggctatacc
    31441 gccttaacgt ttattattat accttgaaaa tgattttcag tcaatagttt tttcagtttt
    31501 ttgtaccata gcgtgattcg aatgtgatgc caagttttct atgggaaaaa atttaccaaa
    31561 aacctactga aaccccttga aaaatctagc taaatagggt ataatatggg taatcatttg
    31621 tcgtaggttt tgtctgaaat attgtccaga caaggctcac agcagttaaa tcttctgaaa
    31681 aagtcagatt tagctgctct ttttgtgctt tttttcaaga ttttgagcat ttgtaacaga
    31741 ggcttaaaga ttctgaaaat tcgtcaagag gacacggtga taaggggttt acaaccatat
    31801 gacgattaga aaagcctgat tgataaggct tggaacttat ttacaaagga gaatcatctt
    31861 ggcaggacat gacgttcaat acgggaaaca tcgtacccgt cgtagttttt caagaatcaa
    31921 agaagttctt gacttaccaa atttgattga aattcaaact gactcattca aagctttcct
    31981 agaccacggt cttaaggaag tgtttgaaga tgtattgcca atttcaaact tcacagacac
    32041 aatggagttg gaatttgttg gatatgaaat caaggaacca aaatacacgc tagaagaagc
    32101 tcgtatccac gatgctagct actcagcacc aatttttgta accttccgtt tgatcaataa
    32161 agaaacaggc gaaatcaaga cccaagaagt tttctttggt gatttcccaa tcatgacaga
    32221 aatgggtact ttcatcatca atggtggtga acgtattatc gtttctcagt tggtccgctc
    32281 accaggtgtt tactttaacg acaaagtaga caaaaatggt aaggtgggct atggttcaac
    32341 tgttatccct aaccgtggag cttggttgga acttgaaagc gactcaaaag atatcaccta
    32401 cactcgtatc gaccgtactc gtaagattcc atttacaacc ttggttcgtg ctcttggttt
    32461 ctcaggtgat gatgaaatct ttgatatctt tggtgacagc gaattggttc gcaacactgt
    32521 tgaaaaagat atccacaaga atccaatgga ctctcgtaca gacgaagcct tgaaagaaat
    32581 ttacgaacgc cttcgtccag gtgagcctaa gacagctgaa agctcacgta gcttgcttgt
    32641 ggctcgcttc tttgacccac gtcgctatga cttggcagca gttggtcgtt acaaaatcaa
    32701 taaaaaactc aatgttaaaa cacgtttgct caaccaaacc attgcagagc cattggtaga
    32761 ccctgaaact ggagaaatct tggtagaagc tggtacgatt atgactcgta gcgtgattga
    32821 aagcattgaa agccatttgg atggcgactt gaacaagatt gtctacatcc caaacgatgc
    32881 agccgttgtg actgagcctg ttgttcttca aaaattcaag gttgttgctc caactgatcc
    32941 agatcgcgtc gtaacgatca ttggtaatgc taacccagat gacaaggttc gtacggtgac
    33001 tcctgcagat atccttgctg agatgagcta cttcctcaac ttggctgaag gacttggccg
    33061 tgtagatgat atcgaccacc ttggaaatcg tcgtatccgt gcggttggtg aattgcttgc
    33121 caaccaagta cgtttgggac tttctcgtat ggaacgtaat gtccgtgaac gtatgtctgt
    33181 tcaggacaat gaagtcttga caccacaaca aattatcaat atccgtcctg taacagctgc
    33241 agttaaagaa ttctttggtt catcacagtt gtcacagttc atggaccaac acaacccgct
    33301 ttctgagttg tctcacaaac gccgtttgtc agccttagga cctggtggtt tgactcgtga
    33361 ccgtgctgga tatgaagtac gtgacgtgca ctacactcac tatggtcgta tgtgtccaat
    33421 cgagacacct gaaggaccta acatcggttt gatcaataac ttgtcatctt acggacactt
    33481 gaacaaatat ggttttgttc aaacaccata ccgtaaggtt gaccgtgaaa caggtgttgt
    33541 cacgaacgaa attgtttggt tgacagctga tgaagaagat gaatatactg tagctcaggc
    33601 taactctcgt ctgaatgaag atggaacctt tgctgagaag attgtcatgg gacgtcacca
    33661 aggggtcaac caagagtatc cagctaatat tgttgactac atggacgttt caccaaaaca
    33721 ggtagttgcc gttgcgacag catgtattcc tttcttggaa aacgatgact ccaaccgtgc
    33781 cctcatggga gccaatatgc aacgtcaggc tgtgccattg attaatcctc aggcacctta
    33841 cgttggtact ggtatggaat accaagcagc ccacgattct ggtgcggctg tgattgctca
    33901 gtatgatggt aaagttactt acgcagatgc tgacaaggta gaagttcgtc gtgaagatgg
    33961 atcattggat gtttaccaca tccaaaaatt ccgtcgttca aactcaggta ctgcttacaa
    34021 ccaacgcact ctcgtaaaag ttggtgacgt cgttgaaaaa ggcgatttca tcgctgacgg
    34081 accttctatg gaaaatggag aaatggcgct tggacaaaac ccaatcgttg cctacatgac
    34141 ttgggaaggt tacaacttcg aggatgccgt tatcatgagc gaacgcttgg tgaaggacga
    34201 tgtctacaca tctgttcacc ttgaagaata cgaatcagaa acgcgcgata caaagcttgg
    34261 gcctgaagaa atcactcgcg aaattccaaa cgttggtgaa gatgccctca aagaccttga
    34321 cgaaatgggg attatccgta ttggtgctga ggttaaagaa ggtgatattc ttgtaggtaa
    34381 agtaacacct aagggtgaga aagatctttc agctgaagaa cgtctcttgc acgctatctt
    34441 tggagacaag tctcgtgaag tgcgtgatac ttctcttcgt gtaccacacg gtgccgatgg
    34501 tgtcgttcgt gatgttaaga tctttacacg tgtaaatgga gatgagttgc aatcaggtgt
    34561 taacatgttg gttcgtgttt acatcgctca aaaacgtaag attaaggtcg gagataaaat
    34621 ggccggacgt cacggaaaca aaggggttgt ctctcgtatc gttcctgtag aagacatgcc
    34681 ttaccttcca gacggaactc cagtcgacat catgttgaac ccacttgggg tgccatcacg
    34741 tatgaatatc ggtcaggtta tggagcttca ccttggtatg gcagctcgta ctcttggtat
    34801 tcacattgcg acaccagtct ttgatggagc aagttctgaa gatctttggt caactgttaa
    34861 agaagcaggt atggatagcg atgccaagac aatcctttac gatggacgta caggtgaacc
    34921 atttgataac cgtgtttctg ttggagtcat gtacatgatc aaactccacc acatggttga
    34981 cgataaattg catgcgcgtt cagtcggacc ttactcaact gttacccaac aaccactcgg
    35041 aggtaaagct cagtttggtg gacaacgttt cggtgagatg gaggtttggg ctcttgaagc
    35101 ctacggtgcg tcaaatgtcc ttcaagaaat cttgacttac aagtcggacg atatcaacgg
    35161 acgtttgaaa gcctatgaag ctattacaaa aggcaaacca attccaaaac caggtgttcc
    35221 agaatccttc cgagttcttg tcaaagaatt gcaatctctt ggtcttgaca tgcgtgtcct
    35281 agacgaagat gaccaagaag tggaacttcg cgacttggat gaaggaatgg acgaagatgt
    35341 catccacgta gatgaccttg aaaaagcccg cgaaaaagca gcccaagagg ctaaagcagc
    35401 ctttgaagct gaagaagctg agaaagcaac aaaagcggaa gcaacagaag aagctgctga
    35461 acaagaataa gcagttcact tagaatagaa agggaagaaa tagtggttga tgtaaatcgt
    35521 tttaaaagta tgcaaatcac cctagcttct ccaagtaaag tccgttcatg gtcttatgga
    35581 gaagtcaaaa aacctgaaac aatcaattat cgtaccttga aaccagaacg tgaaggactc
    35641 tttgatgaag tgatctttgg tcctacaaaa gactgggaat gtgcttgtgg taagtacaaa
    35701 cgcattcgtt acagaggaat tgtttgtgac cgctgtgggg ttgaagtaac gcgtacgaaa
    35761 gttcgtcgtg agcgtatggg acatatcgaa ttgaaagctc ctgtatctca catctggtac
    35821 ttcaagggga ttccaagccg tatgggcttg acccttgata tgagccctcg tgccctcgag
    35881 gaagttatct actttgcggc ttatgtggtg attgatccta aggatacacc acttgagcac
    35941 aagtctatca tgacagagcg cgaataccga gagcgcttgc gcgaatatgg ttatggttca
    36001 tttgttgcca agatgggtgc cgaagccatc caagaccttt tgaagcaagt agatcttgaa
    36061 aaagaaattg ctgaactcaa agaagaattg aaaacagcta ctggacaaaa acgtgtcaaa
    36121 gccatccgtc gtttggatgt tttggatgcc ttttacaagt ctggaaacaa acctgaatgg
    36181 atgattctta acatccttcc ggttatccca ccagatcttc gtccaatgtt gcagttggat
    36241 ggtggccgtt ttgcctcatc tgacttgaat gacctttacc gccgtgttat caatcgtaac
    36301 aaccgtttgg ctcgtttgct tgagttaaat gcaccaggta tcatcgttca aaatgagaaa
    36361 cgtatgcttc aagaagcagt tgacgctttg attgacaatg gtcgtcgtgg tcgtccaatc
    36421 acaggaccag gtagccgtcc attgaaatca ttgagccaca tgcttaaagg taaacaagga
    36481 cgcttccgtc aaaacttgct cggtaaacgt gttgacttct caggacgttc agttatcgcc
    36541 gttggtccaa ctcttaagat gtaccaatgt ggtgtgccac gtgaaatggc gattgaactc
    36601 tttaaaccat ttgtcatgcg tgaaatcgtt gcccgtgata tcgtgcaaaa cgtcaaagca
    36661 gctaaacgct tggtggaacg cggagatgag cgtatctggg atatccttga agaagtgatt
    36721 aaagaacacc cagtgctttt gaaccgcgca ccgacccttc accgtttggg tatccaagcc
    36781 ttcgagccag tcttgattga tggtaaggct cttcgcttgc acccacttgt ctgtgaagcc
    36841 tacaatgctg actttgacgg ggaccaaatg gccattcacg taccactttc agaagaagca
    36901 caagcagaag ctcgtatcct catgctagct gctgagcaca tcttgaaccc gaaagatggg
    36961 aaaccggtag ttactccatc tcaggacatg gttttgggta actactactt gaccatggaa
    37021 gaagctggtc gcgaaggtga aggaatggtc ttcaaagacc gtgacgaagc ggttatggct
    37081 taccgcaatg gttatgttca cctccactca cgtgttggta tcgcaacaga cagcctcaac
    37141 aagccttgga cagaagagca aagacataag gtcttgctta caacagttgg taaaattctc
    37201 ttcaacgata tcatgccaga ggggctacca tacttgcaag aaccaaacaa tgccaacttg
    37261 acagaaggtg ttccagctaa atacttcttg ccacttggtg gagatatcaa ggaagctatc
    37321 agcaatcttg agctcaaccc tccattcaag aagaaaaacc tcggaaatat catcgctgaa
    37381 atcttcaaac gtttccgtac gacagaaact tctgccctac ttgaccgcat gaagaacctc
    37441 ggttaccacc actcaactct tgcaggattg acagtgggta ttgccgatat cccagtcgtt
    37501 gatgacaagg ctgaaatcat tgaagaatca cacaaacgtg tcgaacaaat caccaaacaa
    37561 ttccgtcgtg gtatgatcac agacgacgag cgttacaatg ctgttacagc tgaatggcgt
    37621 gctgcccgtg aaaaacttga gaaacgcttg attgctaatc aagatcctaa gaacccaatc
    37681 gttatgatga tggactctgg agcccgtggt aacatctcaa acttctcaca gcttgccggt
    37741 atgcgtggtc tgatggctgc tccgaatgga cgtatcatgg aattgccaat cctttcaaac
    37801 ttccgcgaag gtttgtcggt attggaaatg ttcttctcaa ctcacggtgc tcgtaaaggt
    37861 atgaccgata cggcccttaa gacagccgac tcaggttact tgactcgtcg tttggtcgac
    37921 gttgcccaag acgttatcat ccgtgaggac gactgtggaa ctgaccgtgg tctcttgatc
    37981 cgttctatcg cagaaggaaa agagatgatc gagtctctcg aagagcgtct caacggtcgt
    38041 tacactaaga aaactgttaa acatccagaa actggtgcag tgattattgg tccaaatgaa
    38101 ttgattacag aagacaaggc gcgtgaaatt gtcaatgctg gtgtggaaga agtgactatc
    38161 cgttctgtat ttacatgtaa cactcgtcac ggtgtctgcc gtcactgtta cggtatcaac
    38221 ttggcgactg gtgatgcggt tgaagttggt gaagcagttg gtacaatcgc tgcccaatct
    38281 atcggggaac ctggtacaca gcttacaatg cgtaccttcc acacaggtgg ggttgcctca
    38341 aataccgata tcactcaggg tcttcctcgt gtccaagaaa tctttgaagc ccgcaatcct
    38401 aaaggggaag cggttatcac agaggttaaa ggacaagtta ctgctatcga agaggatgca
    38461 tcaactcgta ccaagaaagt ctttgttaag ggtgaaactg gcgaaggtga atatgtcgtt
    38521 ccatttacag ctcgtatgcg tgtcgaagtt gggggccaag tagcgcgtgg tgctgctctg
    38581 acagaaggtt ctatccaacc aaaacgtctc cttgcagttc gtgatgtctt gtcagttgaa
    38641 acgtaccttc tcggtgaagt acaaaaagtt taccgtagcc aaggggtaga aatcggtgac
    38701 aaacacatcg aggtaatggt tcgtcaaatg atccgtaaag tccgtgtcat ggatccaggt
    38761 gatacagatc ttctcatggg taccctcatg gatatcaatg actttacaga tgccaacaaa
    38821 gatgtcctta tcgcaggtgg agttccagcg acaggtcgcc cagtccttat gggaattacc
    38881 aaagcctcac ttgaaacaaa cagtttcttg tcagcggctt ccttccagga aacaactcgt
    38941 gtccttactg acgcagctat ccgtggtaag aaagaccatc tccttggact taaagaaaat
    39001 gttatcatcg gtaagatcat cccagctggt actggtatgg cccgttaccg taaccttgaa
    39061 ccacatgctg tcaacgaaga agaatacctt aatcctccag tagaggaaga aggaaatgaa
    39121 gaaacaacag aagtagttgt ggatactgcc gttgaaactg tggaagaaac agtagaataa
    39181 gagagaatga gagaaccctc gggttctctc attctctctt ctgaaaactt tctccatttt
    39241 tccacgaaat gtggtaaaat aaaagaaaga agctgacaaa ggagacgggt atggaacaaa
    39301 cattctttat catcaaacca gatggtgtaa aaagagggct agtgggtgaa gtgttaaagc
    39361 gcatcgaaca acgtggattt acaatcgaaa aattggagtt tcgttcacag gtttcagaag
    39421 agttgattga ccagcactat caggacttgg ttggtcagag tttttaccca ccgattcgtg
    39481 aattcatgac ttcaggtcca gttcttgtgg gtgtcatttc tggtcccaaa gtaatcgaaa
    39541 cttggcggac catgatgggt gcaactcgtc cagaagaagc tttaccaggc actattcgag
    39601 gtgattttgc aaaagctgct ggagaaaatg agattatcca aaatgttgta catggttcag
    39661 attcagaaga gtcagctaag cgagaaattg ctctttggtt ttaagagtgg attggctcaa
    39721 tcaattggtt aaaagctcat ttgaatagaa agtatagtca attagtttaa gacatgacgc
    39781 atgatatcaa actttttagt ttttgatatg gtgcgttttt tgattaagtg actattagtt
    39841 tgtctcgctc cgttaggtgc gagacaaaaa aaacacccgc tatgcgggtg cgcgtcgaag
    39901 gttataccaa aaaaactcca aacgcgatac aataaaggtg ttcaatccaa ttgtaaagcg
    39961 aaaggagaaa aatatggcac aaaaggttct tttatcctgt tcttgtttca attgactata
    40021 tttctatact ttttcttcct ttctctgtga aaatcgcaag tttttcccac cttttctcaa
    40081 tactgaaaca acatctttcc agaacttcaa taatttcttt ttgtgttaaa tcattattta
    40141 actaaatctt tggaggcaat acgttttcaa agctactttt ttaccatagg ttttgagcct
    40201 tcaacacaga ttactaagcc aaaaatgctc taaatttttg aaattctaac aaattccact
    40261 caactttatc atcatctttg actttcacaa tatcttcctc aaaataacat ggaataaaga
    40321 tagttttctt ttaaaacggt tgtaggagga aaatctctcc tacactatta ttgattctga
    40381 gagaaaattg caaaatatca tctaccaaac tttcaattat taagattttt tgcagtttat
    40441 ctgaattaga atcgcaaggc ttctcaataa tataattgtc gaattttttc attctaactt
    40501 cctctccatt atttcttcct ttatcaagaa aaagttacct caatattaat aaagtacaat
    40561 tctaaattaa ctccaattct tgattcatga taatatttca gtaactcatc gtgcaattaa
    40621 aaacaaggat ttttatttca gatgatccat cgtgaacact tcatcagcca tctcccaaat
    40681 tgccggatta tgtgttgcga taatgattag cctattatca tctcgaagag atagcaaaat
    40741 ctccataatc aactgagagg ttgctgggtc tattgaagct gttggctcat ctgccagaat
    40801 aaagggtgga ttctttaaga taatttttgc caaggcaacc cgttgcgatt ctccgcccga
    40861 taactcaaag atgcgcttat ctaggtcaag ataagccagg ccgacctgtt ctaaagcctg
    40921 cttctgcctc aaccgctgtt ccgaccgact caacttttga ccaatgagac ctagcttaag
    40981 gttttcttca atactttggt tttcaattaa gccaaagttc tggaagaggt agcccaattc
    41041 gtgacggaaa aaatcactcg atttataatt ggccaagtct ttacctcggt aaaaaatcgt
    41101 cccatcataa ggttctaatt tcccaatcat gttcatcaag gttgtttttc cgctaccact
    41161 tgaaccaatt aaggcataga cttttccagc ctcaaatgtc attgaaagat tcgaaaataa
    41221 ctctcgttct ccaaaagatt tactcacctg tttaagttca atcatattaa cctcccttca
    41281 aaacaagaat ggacatcttg ttttctttct gcatttggac atgtaactgt aaaagagata
    41341 gaccagtaaa gagtaacaag actaagaaag caactcctat ctctacctga agaaatacac
    41401 tcgcaacaaa tcccagtaaa aacacaccca gttgagcaaa gagataagtg cgatggattt
    41461 ctaagaacct gagacctgca atgcgtttga taaaaatggc acgtctaaat tcttcaaagt
    41521 agagcctatt catagtgtta aacaacaaga ttgaagttgc aatcccaagc acagctcctg
    41581 ctagcattac ccaacgttcc ctctggatat tatccaataa tgtgatgtag ttgtggtaac
    41641 ctgtttgcat ttctgagacc caattttcaa tgccttgtct ctggataagc tcctgggcat
    41701 cagacaattg attaaagaga acgtagttct gtactgcgtc tatccaaaac aaaatggact
    41761 gtggaccagt tgattggggt gttataacaa tgatgattgg atctttcaaa aactgctggt
    41821 aagaaatagg ggtcgtatta tacacaaaac gatcctgacc tgattctaaa taacctaccg
    41881 tagcagtcat ttgctgtcgt tcatcttgac tagacatgcg actggttaag tcgtcttcaa
    41941 aaacagattt ataatgttct tcctctgaac ggaggtgttc aggcagcaat aagacaaact
    42001 cccctacatc aaggtgattc atcttttgct caatagttgt atctacagga atgttttgac
    42061 gctccaagta ttgcggtgtg acgataagga cattgccatt cgggctgtaa tcgtgccatt
    42121 ctgtagaggt tataaagttt ttggaggaag ccatgccatt ttgcaaagta cggtcaatta
    42181 actggtgtct agataagaaa gccttttgtt ctgaaacagc cagatccatc aattgatacc
    42241 aagttctgag tttcctttga gcttgttcat caaaaccagg actcgttcct tcacggctga
    42301 ttgatagggt aatcagttgc ctttcctggc tccaagcctc ttgtccaatc cgatgctgtt
    42361 gccaggcttg ggaatacttt aagctactcc ctattcccag cgttacaata ataatcgcta
    42421 atagttgacc gattaaaatc aaactaatga ttcctctgac aggcacttgc ccttttataa
    42481 tctgcatcag gtgtatcttt tttatcccaa ctgcgaagag ttgagcgaaa aacagggaga
    42541 tagacaacaa gatgagatta taactgagca agcctgctcc tatggtcatt agggattgcg
    42601 ttggaagcga cagaattttt tgcataagaa tggtgagcac gccagctaaa ctgaaaccaa
    42661 cagctatccc tttcaaatca tcaccaactg gtctaagaaa aatggaccac cgtttctctc
    42721 ctgaaatgag gcgaatgccc gacgaccgta attggctaat ttgactaatt aaagtcagtg
    42781 ctccaaaggt taagatgaaa atcaatagac tgattaactg aaatccgtta ctaaagatag
    42841 ccattaacgt agatagttta gatggaattg tcaggtgcat attagtcaag ccaagttgac
    42901 ttagctcctc ccttagcaag tgaatatcta ggtgtccatc gaatacaaaa tagtttgttt
    42961 caacactact actttgagca tcttctagtt ttttttcctg tagcccgtca ggcaactttc
    43021 cgtctccaaa ggtcgtataa gaaaaaactg tagtaccttc tgagttagga tcttggtgtt
    43081 gaatcgcaat aaagctatct gtttcttctg ctagtttttc caagcgtgta gcaacatgct
    43141 gaaaagttgt ttcaggggaa gaatcatgta caacaacgtt ggggtaataa tgggagacat
    43201 atgtatcagt ccaaatggta aatacccaaa caaagaacaa actagcaagc aggttggata
    43261 tgagtataaa taattttttc atagtgcatt ccttattcta aaacagaggg cagaaatacc
    43321 cctgccctct ataaactaac aagcttacta aactattgat aaaagaatct tcttcaatta
    43381 ttctttacca tcccgcatca aatgtaattc gctcccccaa atttgtatta acaaacgcat
    43441 aggccgcact atgtgctcct gcataaactg ttttttgatt gtcacgttca ttacttccaa
    43501 cataggccca gtgatactgt gaaccatgat aataattcga aaatgctccc caattatatg
    43561 gatcatgatg gcctccatag gtccactcgc caccacggtg agaaactgcc aaaacaggaa
    43621 gagccaaact aaatgccaaa acggcaaggg atgatgcaac tacttttcta aattttaaca
    43681 tattattact cctctaaatg aaatattatg aaaatgagcg aaatgcaact acatatttta
    43741 attagaaatc tcagtctgaa ttatagtatc ctattttttc ctcctttcta actgcacgtt
    43801 cctttctaca ggcagagacc taattttata aaccaatctt aaatacttta gattttgtaa
    43861 ctcataattt tcaacagttg gttagctatg aaagcatttt atcaaacatc tccattctta
    43921 tatctatctg gtattgttac aagctctcat cagaatacct ttctctaaat agttgaattt
    43981 taaagtaata taaaatcaat cagccttccc aacatcaaga ccattggact tcttttgcga
    44041 ttgcactcga atctccaatt gtttattctt ctgaataaac tgttggtaag gaattgtatt
    44101 actaaacata aaaacaccta gcaatgcaaa tgtaactaat tttttaattc cacgtttttt
    44161 ccatgcaatg aaa
//
LOCUS       DAVLZS010000013        44158 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLZS010000013 DAVLZS010000000
VERSION     DAVLZS010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.013"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            131..3232
                     /locus_tag="VYO88_000732"
     CDS             131..3232
                     /locus_tag="VYO88_000732"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1718872.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLV
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAGQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKHPLLEPLVKV
                     GLFDLFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVRKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQKIREAVAERFWIQ
                     VKNHDSEQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            3314..4321
                     /gene="pfkA"
                     /locus_tag="VYO88_000733"
     CDS             3314..4321
                     /gene="pfkA"
                     /locus_tag="VYO88_000733"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1718873.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4380..5885
                     /gene="pyk"
                     /locus_tag="VYO88_000734"
     CDS             4380..5885
                     /gene="pyk"
                     /locus_tag="VYO88_000734"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1718874.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6201..6449)
                     /locus_tag="VYO88_000735"
     CDS             complement(6201..6449)
                     /locus_tag="VYO88_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1718875.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDK"
     gene            complement(6615..7376)
                     /locus_tag="VYO88_000736"
                     /pseudo
     CDS             complement(6615..7376)
                     /locus_tag="VYO88_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107579.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            7688..8560
                     /locus_tag="VYO88_000737"
     CDS             7688..8560
                     /locus_tag="VYO88_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1718876.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8706..9050)
                     /locus_tag="VYO88_000738"
                     /pseudo
     CDS             complement(8706..9050)
                     /locus_tag="VYO88_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9193..9504
                     /locus_tag="VYO88_000739"
     CDS             9193..9504
                     /locus_tag="VYO88_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718877.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9508..10224
                     /locus_tag="VYO88_000740"
     CDS             9508..10224
                     /locus_tag="VYO88_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1718878.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEISSLMNEWLAYFL"
     gene            complement(10354..11169)
                     /locus_tag="VYO88_000741"
     CDS             complement(10354..11169)
                     /locus_tag="VYO88_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1718879.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYSDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11166..12071)
                     /locus_tag="VYO88_000742"
     CDS             complement(11166..12071)
                     /locus_tag="VYO88_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1718880.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLSYSLLIGVIL"
     gene            12413..12769
                     /locus_tag="VYO88_000743"
     CDS             12413..12769
                     /locus_tag="VYO88_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1718881.1"
                     /translation="MLHQGDKNSLLESLSIVERQTLKDIEVIIVNQSTEEIASISQQM
                     NLSFNIKIIDENSFAELSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGH
                     FADLVDGVFYFYPWGG"
     gene            12774..13778
                     /locus_tag="VYO88_000744"
     CDS             12774..13778
                     /locus_tag="VYO88_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEV1718882.1"
                     /translation="MTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQF
                     DINNLIWRLYIHSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLEN
                     YDIERAKKQYIQELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTII
                     SNNCVGGLIYKQLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPNWT
                     HEVYPLGHLGDIDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNK
                     MDNLPYSNKLILVNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL
                     "
     gene            13880..16009
                     /locus_tag="VYO88_000745"
     CDS             13880..16009
                     /locus_tag="VYO88_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1718883.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRSTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DINDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            15996..16445
                     /locus_tag="VYO88_000746"
     CDS             15996..16445
                     /locus_tag="VYO88_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1718884.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTRRYRCGLCRGKLLLINQPED"
     gene            16504..16776
                     /locus_tag="VYO88_000747"
     CDS             16504..16776
                     /locus_tag="VYO88_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1718885.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(17130..17321)
                     /locus_tag="VYO88_000748"
     CDS             complement(17130..17321)
                     /locus_tag="VYO88_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718886.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            17749..18507
                     /locus_tag="VYO88_000749"
     CDS             17749..18507
                     /locus_tag="VYO88_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1718887.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTVAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            18509..20497
                     /locus_tag="VYO88_000750"
     CDS             18509..20497
                     /locus_tag="VYO88_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1718888.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(20539..21183)
                     /locus_tag="VYO88_000751"
     CDS             complement(20539..21183)
                     /locus_tag="VYO88_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV1718889.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFTAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(21209..22084)
                     /locus_tag="VYO88_000752"
     CDS             complement(21209..22084)
                     /locus_tag="VYO88_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1718890.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPDKKQASTNFKPAGQSIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRK
                     SRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHP
                     YASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWM
                     ANLNLKFSVRNKSRN"
     gene            22791..24266
                     /locus_tag="VYO88_000753"
     CDS             22791..24266
                     /locus_tag="VYO88_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1718891.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSARKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(24232..24947)
                     /locus_tag="VYO88_000754"
                     /pseudo
     CDS             complement(24232..24947)
                     /locus_tag="VYO88_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            25203..26063
                     /gene="speE"
                     /locus_tag="VYO88_000755"
     CDS             25203..26063
                     /gene="speE"
                     /locus_tag="VYO88_000755"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1718892.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            26060..27319
                     /locus_tag="VYO88_000756"
     CDS             26060..27319
                     /locus_tag="VYO88_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1718893.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIGSYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            27319..28446
                     /gene="nspC"
                     /locus_tag="VYO88_000757"
     CDS             27319..28446
                     /gene="nspC"
                     /locus_tag="VYO88_000757"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1718894.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            28443..29528
                     /gene="aguA"
                     /locus_tag="VYO88_000758"
     CDS             28443..29528
                     /gene="aguA"
                     /locus_tag="VYO88_000758"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1718895.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            29538..30413
                     /gene="aguB"
                     /locus_tag="VYO88_000759"
     CDS             29538..30413
                     /gene="aguB"
                     /locus_tag="VYO88_000759"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1718896.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(30594..31403)
                     /locus_tag="VYO88_000760"
     CDS             complement(30594..31403)
                     /locus_tag="VYO88_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1718897.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            31675..31896
                     /locus_tag="VYO88_000761"
     CDS             31675..31896
                     /locus_tag="VYO88_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV1718898.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            31950..32621
                     /locus_tag="VYO88_000762"
     CDS             31950..32621
                     /locus_tag="VYO88_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1718899.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(32673..32870)
                     /locus_tag="VYO88_000763"
     CDS             complement(32673..32870)
                     /locus_tag="VYO88_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1718900.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            32863..33771
                     /locus_tag="VYO88_000764"
     CDS             32863..33771
                     /locus_tag="VYO88_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1718901.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            33768..34229
                     /locus_tag="VYO88_000765"
     CDS             33768..34229
                     /locus_tag="VYO88_000765"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1718902.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            34219..35106
                     /locus_tag="VYO88_000766"
     CDS             34219..35106
                     /locus_tag="VYO88_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1718903.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            35109..36992
                     /gene="cbpE"
                     /locus_tag="VYO88_000767"
                     /gene_synonym="pce"
     CDS             35109..36992
                     /gene="cbpE"
                     /locus_tag="VYO88_000767"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV1718904.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELSVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            37072..38202
                     /locus_tag="VYO88_000768"
     CDS             37072..38202
                     /locus_tag="VYO88_000768"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1718905.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            38212..39474
                     /locus_tag="VYO88_000769"
     CDS             38212..39474
                     /locus_tag="VYO88_000769"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1718906.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            39478..40275
                     /gene="proC"
                     /locus_tag="VYO88_000770"
     CDS             39478..40275
                     /gene="proC"
                     /locus_tag="VYO88_000770"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1718907.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTSASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            40391..41029
                     /locus_tag="VYO88_000771"
     CDS             40391..41029
                     /locus_tag="VYO88_000771"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1718908.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            41026..41916
                     /locus_tag="VYO88_000772"
     CDS             41026..41916
                     /locus_tag="VYO88_000772"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1718909.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            41956..42273
                     /gene="yabA"
                     /locus_tag="VYO88_000773"
     CDS             41956..42273
                     /gene="yabA"
                     /locus_tag="VYO88_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1718910.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            42276..43145
                     /gene="rsmI"
                     /locus_tag="VYO88_000774"
     CDS             42276..43145
                     /gene="rsmI"
                     /locus_tag="VYO88_000774"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1718911.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            43372..43890
                     /locus_tag="VYO88_000775"
     CDS             43372..43890
                     /locus_tag="VYO88_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV1718912.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            43999..>44158
                     /locus_tag="VYO88_000776"
     CDS             43999..>44158
                     /locus_tag="VYO88_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1718913.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKN"
BASE COUNT        13416 a         7865 c         9704 g        13173 t
ORIGIN      
        1 tataaaaacg atgacaaaaa tacaaatgaa tagaaaataa attagtaagc tgatgaaatt
       61 tttctcaaga gaagctattt ataggtgaaa atggtataat atagtgagaa ggatagagga
      121 gaagtgtaaa ttgatcgcac aactagatac aaaaacagtc tatagtttta tggaaagcgt
      181 catttcgatc gaaaagtatg tgagagcagc taaagaatac ggctacactc atttggctat
      241 gatggatatt gacaatcttt atggcgcttt cgactttcta gagattacaa aaaaatacgg
      301 cattcatcct ttgctagggc ttgaaatgac agtgtttgta gatgatcagg aagtgaattt
      361 gcgcttttta gctctatcta gtgtgggcta tcagcagttg atgaagcttt cgacagccaa
      421 gatgcagggg gagaaaactt ggtcagtcct gtcccagtac ctggaggata tcgcggtcat
      481 tgtgccttat tttgatagag ttgagtcgtt agaactaggc tgtgattact atataggggt
      541 ttatccagaa acactagcaa gcgaatttca tcatcctatc ttacctcttt atcgggtcaa
      601 cgcttttgaa agcagggata gagaagttct tcaagtttta acagcgatta aagaaaatct
      661 accgctcaga gaagttccct tgcgttcgag acaagatgtc tttatatcag caagttcttt
      721 agagaaacta ttccaagagc gttttccgca agctttggac aatttagaaa agcttatttc
      781 aggcatttct tacgacttgg atactagtct gaaactgcct cgttttaatc cagctagacc
      841 agcagtagag gagttgagag agcgtgctga actggggctt gttcagaagg ggttgactag
      901 taaagaatat caagatagac tagaccaaga attgtctgtt attcatgata tgggctttga
      961 tgattatttc ttggttgttt gggatttgtt gcgttttgga cgatcgaatg gctattatat
     1021 gggaatggga aggggttctg cagtaggcag tttggtttct tatgccttag acatcacggg
     1081 gattgaccca gtagagaaaa atctgatttt tgaacgcttt cttaatcgtg aacgctatac
     1141 catgcctgat attgatattg atatcccaga tatttatcgt ccagatttta tcagatatgt
     1201 tggtaataaa tatggtagta aacatgcggc acaaatcgtt actttttcaa cctttggagc
     1261 caagcaagct cttcgagatg tcttgaaacg ctttggtgtg ccagagtatg aattatctgc
     1321 aattactaag aaaatcagtt ttcgtgacaa tcttaagtcg gcctatgagg gcaatctcca
     1381 gtttcgtcag caaatcaata gtaagttaga ataccaaaaa gcttttgaga ttgcttgcaa
     1441 gatagagggc tatccaaggc aaacctctgt ccatgcggct ggtgttgtaa ttagtgacca
     1501 agatttgacc aactacattc ctctaaagta tggtgatgaa attccactga ctcagtatga
     1561 tgctcatgga gttgaggcta gcggactttt gaagatggac tttctgggac tacgaaattt
     1621 gacctttgtc cagaagatgc aagagttgct tgttgaaaca gaaggtattc accttaaaat
     1681 tgaagaaata gatttggaag acaaagaaac gttagattta tttgcctctg gaaatacaaa
     1741 aggtatcttt caatttgagc aacctggtgc tattcgcttg ctcaaacgtg ttcaaccagt
     1801 ctgttttgaa gatgtcgtag caactacttc tctaaatcga ccaggtgcaa gtgactacat
     1861 caataatttt gtggcaagga agcatgggca ggaagaagtg actgttctag attcagctct
     1921 ggaggatatt ttggctccaa cttatggcat tatgctctat caggagcagg ttatgcaggt
     1981 tgctcagcga tttgctggat ttagtcttgg gaaggccgat attttgcgtc gagctatggg
     2041 taaaaaggat gcctctgcta tgcatgagat gagggcttcc tttattcaag gctccataga
     2101 agcaggccat actgcggaaa aagcagggca ggtttttgat gttatggaga agtttgcagg
     2161 ctatggtttt aacaggtcac acgcctatgc ctactcagca ttggccttcc agttggctta
     2221 ttttaaaaca cattatccag ccatatttta tcagattatg ttgaattctg ccaacagtga
     2281 ttatgtaaca gatgccttag aagcaggttt tgaagtagcc ccattgtcca tcaatactat
     2341 tccctatcac gataaaattg ccaacaagtc tatctatata ggtttgaaat cgattaaggg
     2401 gctcagcaag gacttggcgc tttggattat tgaacataga ccttattcta atattgaaga
     2461 ttttatagct aaattacctg agaattatct gaaacatcct ctgctagaac ctttggtaaa
     2521 agttggcctt tttgatttat ttgaaaaaaa tcgtcaaaaa gtatttaata acttagctaa
     2581 tctatttgaa tttgtgaaag agttgggaag tttgtttgga gatgctattt atagttggca
     2641 ggaatcggaa gattggacgg aacaagaaaa attttatatg gaacaagagc ttttagggat
     2701 aggtgtcagc aaacatccac tacaagctat tgcaagtaag gctatttacc cgattacccc
     2761 aatcggaaat ttgtcagaaa atagctatgc tattattttg gttgaagttc ggaaaataaa
     2821 agtgattcgt accaaaaagg gtgaaaatat ggccttctta caggcagatg atagtaagaa
     2881 aaaattggat gtcactctct tttcagactt atatcgtcag gttggacagg aaataaaaga
     2941 gggagccttc tactatgtaa aaggaaaaat acaatcacgt gatggccgtc tgcaaatgat
     3001 tgcacaaaaa ataagagaag cagttgctga acgcttttgg attcaggtta aaaatcatga
     3061 ctcggagcaa gagatgtcac gtattttaga ccagtataaa ggcccaatcc cagtcatcat
     3121 ccggtatgaa gaggaacaga aaaccatcgt ttctccccat cattttgtag ctaaatctga
     3181 tgaattagag gcgaaattga atggaatagt tatgaaaacg atttatcgct aaaattacgg
     3241 aaaatagaag aattttcaac gtaaatgtgg tataatcagt aagaatgtta aaagaaaaag
     3301 gagcataacc aatatgaaac gtattgctgt tttgactagt ggtggagacg cccctggtat
     3361 gaacgctgcc atccgtgcag ttgttcgtca agcaatttca gaaggaatgg aagtttttgg
     3421 tatctatgac ggatatgctg gtatggttgc cggtgaaatt catcccctag atgcagcttc
     3481 agtaggggac atcatttctc gtggtggtac tttccttcac tcagctcgtt acccagagtt
     3541 cgctcaactt gaagggcaac ttaaagggat tgagcaattg aaaaaacacg gaattgaagg
     3601 tgtagttgtt atcggtggtg acggatctta ccacggcgct atgcgtttga ctgaacatgg
     3661 cttcccagct attggtcttc caggtacaat cgataacgat atcgttggta ctgactttac
     3721 aatcggtttt gacacagcgg ttactactgc catggacgct attgataaga ttcgtgatac
     3781 atcatcaagt caccgtcgta cttttgtaat cgaagttatg ggacgtaacg ctggtgatat
     3841 cgctctttgg gctggtattg caactggtgc tgatgaaatc atcatccctg aagcaggctt
     3901 caagatggaa gatatcgtag caagcatcaa agctggttat gaatgtggta aaaaacacaa
     3961 tatcatcgtc ttagctgaag gtgtgatgtc agcggctgaa tttggtcaaa aacttaaaga
     4021 agctggagat acaagcgacc ttcgtgtaac agaacttgga catattcaac gtggtggttc
     4081 tccaactgcg cgtgaccgtg ttttggcgtc acgtatgggt gcacatgctg ttaaacttct
     4141 taaagaaggt atcggtggtg ttgcggttgg tattcgtaac gaaaaaatgg ttgaaaatcc
     4201 aattcttggt actgcagaag aaggggcatt gtttagcctt actgcagaag gtaagattgt
     4261 ggttaacaac ccgcacaaag ccgatattga gctatctagc ttgaataaga gcttgtcata
     4321 atttacaatt tagttaataa gaccaaaaag gtcatatata taaaggagtc acaaaaatca
     4381 tgaacaaacg tgtaaagatc gttgcaactt tgggtcctgc ggtagaaatc cgtggtggta
     4441 aaaaattcgg tgaggatgga tactggggtg aaaaacttga tgttgaagct tcagctaaaa
     4501 acattgctaa attgattgaa gctggtgcta acacattccg attcaacttc tcacacggcg
     4561 accaccaaga acaaggtgag cgtatggcaa ctgttaaact tgcggaaaaa attgcaggta
     4621 aaaaagttgg tttccttctt gatacaaaag gacctgaaat ccgtacggaa ttgttcgaag
     4681 gtgaagctaa agaatattca tacaaaactg gtgaaaaaat tcgtgttgca actaaacaag
     4741 gaatcaaatc aactcgtgaa gtgattgcgt tgaacgttgc tggtgctctt gatatctatg
     4801 atgatgttga agttggtcgt caagttttgg ttgacgatgg taaacttggt cttcgtgtgg
     4861 ttgctaaaga tgatgcaact cgtgaatttg aagttgaagt tgaaaacgat ggtatcatcg
     4921 ctaaacaaaa aggtgtgaac atccctaaca ctaaaattcc tttcccagct cttgctgaac
     4981 gcgataacga cgatatccgt ttcggtcttg aacaaggtat caacttcatc gcaatttcat
     5041 tcgtacgtac tgcaaaagat gtgaacgaag ttcgtgcaat ctgtgaagaa actggaaacg
     5101 gacatgttca attgttcgct aaaatcgaaa accaacaagg tatcgataac ttagacgaaa
     5161 tcatcgaagc agctgatggt attatgattg ctcgtggtga tatgggtatc gaagtaccgt
     5221 tcgaaatggt tccagtttat caaaaaatga ttatcaagaa agtcaatgct gcaggtaaag
     5281 ttgttatcac tgcaacaaac atgcttgaaa caatgactga aaaaccacgt gcaactcgtt
     5341 cagaagtatc agacgtattc aacgctgtta tcgacggaac tgacgctaca atgctgtcag
     5401 gcgagtctgc aaacggtaaa tacccactcg agtcagtaac tacaatggct acaatcgaca
     5461 agaacgctca agctcttctt aatgaatacg gacgtcttga ttcagattca tttgagcgta
     5521 actctaagac agaagtaatg gcttctgctg ttaaagatgc tactagctca atggatatca
     5581 aattggttgt aactcttact aagacaggtc atactgcacg tttgatttct aaataccgtc
     5641 caaatgctga catcttagca ttgacatttg acgaattgac agaacgtggc ttgatgttga
     5701 actggggtgt tatcccaatg ttgacagatg ctccatcttc aactgacgat atgttcgaaa
     5761 tcgctgaacg taaagcggta gaagcaggtc tcgttgagtc aggcgatgat atcgttatcg
     5821 ttgctggtgt gccagtagga gaagctgttc gcacaaacac aatgcgtatc cgcacagtac
     5881 gttaagaaaa atataaaaac ctatcatatc cagctttaga gcttgtgtga taggcttttt
     5941 gtatagaggg taagaaatag gcaaaacttt cataatggat tgatactctt cgaaaatctc
     6001 ttcaaaccac gtcagcgtcg ccttaccgta catatgttac tgacttcgtc agttctatct
     6061 acaacctcaa agcagtgctt tgagcaacct gcggctagct tcctagtttg ctctttgatt
     6121 ttcattgagt atgaaataag atatgcacaa attgattaga aagtcaaatg aatttctaca
     6181 aatgttttag caatcgcaat ctacttgtct agattcgatc tgatatattt tcgatttaat
     6241 gatatggtat ttaaaacctc caaagtagct tgctccattc ttttacttac gtgagtgtag
     6301 atgttattta ctgttttagc gtttttgtgt tccactctaa ccattatagc attcttctca
     6361 gctagtgtac taaggagtgt gtgcctgaaa atatgggaac taaggggctg gtttatcggt
     6421 ttctctagtt tagtatttgc cttttgcaaa gtgatcttaa atgcctttct ctaaatttac
     6481 atatcactat tgtttaacaa aatctaatct attttaggtc acttattctt tttttgaaat
     6541 gtagaatgaa ctttttcaaa gtttttcgaa tcttttaaaa tctgtttgtt ttatatcgcc
     6601 attctccccc ttttttaatt ctccctatat agcctgacaa cttttccgat ggtacgaata
     6661 tggttgcttt cgtctaggtg gatgtcggag tattcgggat tgagtttttt tgaggtagcc
     6721 ttggcggagt ttcttgacat agttagtgcc gtctacttgg aagatgccga tggtattata
     6781 gtcaatctgt ggggtattct tgataaatag gtagtcgctg tttcttatct ttggctccat
     6841 ggacttgctg acgacataag cgattgggtc gtagtcgtct gggataatgg aaactccata
     6901 actaaatcgt cgtcctgcat caagcggcta cctgcagaga taaactacct aacacgagag
     6961 taagtagtct gtctgtagtc gtccagtctg atgattttta cgatacttcg tttttctgat
     7021 catacagttg cctctcggca taggtcagga ctttaccttg tctgggtggt acccgttggt
     7081 cgtagataga ttggatatcg ctaggagaat ccttttgaac tggaggaaag agggcatcaa
     7141 tcaagctact gaatacttta actaagtcaa atatagtatt tttcttagta gacctaaccc
     7201 ttttttcata atttctaatg gtgtttttac ttatacctat cttagtaccc aattcttatt
     7261 gagtccaact attactagtc tatattgttt tatagttgat tgagtttgga atagtacgct
     7321 gtagctgcta aaacatttct aggaattaat ttgcctttcc taatagagtt gttcatatct
     7381 tatttcaatc tattatgttt ttcacctcta acaatcgcaa tctcttcttt atctatgaat
     7441 gaaatcgatt tctatttttg taagtaaagc ataacacgaa atccacgaaa atgaaaacct
     7501 ttgttgtgtt ttcgtaaaaa atttgttgac agagcacgga acgcctacta taattaaatc
     7561 aagcttaagg aaataacaaa aaaacaaatc ggagggaaag acgatgaaca cattaaatga
     7621 gaaagtaatc aatatctgta aagcagtagt taaagaaact ttaatccaag acatttagga
     7681 gaaagaaatg aagaaatcaa gaaaattagc cacattagga atctgttcag ctttgttttt
     7741 aggattggct gcttgtcaac aacaacatgc tacttctgag gggacgaatc aaaggcaaag
     7801 cagttcagcg aaagttccat ggaaagcttc atacaccaac ctaaacaacc aggtaagtac
     7861 agaagaggtc aaatctctct tatcagctca cttggatcca aatagtgttg atgcattttt
     7921 taatctcgtt aatgactata ataccattgt cggctcaact ggcttatcag gagatttcac
     7981 ttcctttact cacaccgaat acgatgttga gaaaatcagt catctctgga atcaaaagaa
     8041 gggcgatttt gttggaacca actgccgtat caatagttat tgtcttttga aaaattcagt
     8101 caccattcca aagcttgaaa agaatgacca gttgcttttc ctagataatg atgcgattga
     8161 taaaggaaag gtctttgatt cacaagataa ggaagagttt gatattctat tttcgagagt
     8221 tccaactgag gcaactacag atgtcaaggt tcacgctgaa aagatggaaa cattcttctc
     8281 acaatttcaa ttcaatgaaa aagctcgaat gctgtctgta gtcttgcacg acaatctgga
     8341 tggcgagtat ctgtttgtag gccacgttgg ggtcttagta cctgctgatg acggtttctt
     8401 atttgtagag aaattgactt tcgaagagcc ctaccaagcg attaaatttg ctagtaagga
     8461 agattgctac aagtatttgg gcaccaagta tgcggattat acaggcgagg gactggctaa
     8521 gccttttatc atggataatg ataagtgggt taaactttaa tagtgttatg atatgacagt
     8581 aatcttagga tttttatttc tatttttgat gacttggtgg gttatttcaa tcgttaatag
     8641 ccagaaacca cgcaaaaatg aaacatttat tggctatatc caaagatacg atattgatgg
     8701 gaatggctat caatcattac cgtgtcctca gaactgagag gagttcttga aatcgtaaaa
     8761 ctactttgaa caagagttac ttcaacccat tggctccgac ggattaagtt gctttcgtga
     8821 acaccaaaat cagccgcaat ttcttcataa gtgcggtatt ctcgcacata ttgaagagtg
     8881 gccataagaa ggtcttctag gcttaattta ggttttcgtc ccccttttgt gtgtttaagt
     8941 tgataagcag tttttaatac agctaacatc tctttaaaag tggtgcgctg aacaccaaca
     9001 agacatttaa atcgtgcatc agttagttgc ttacttgctt cataattcat agaactacta
     9061 taccatattt tgtttcgcag gaagtctaat gctaaaatct tatcagtgag aagatttctt
     9121 aaagtttatt ctttgtagtt tcatctgtat tagtatataa tttaacttag agaaaatagg
     9181 aggactaatc gaatggaatt aaaagatttt acagaaaaag aacaggaaat gattaagaaa
     9241 aggcttacaa tgtctaatat tagtgacaaa gaaactactg agaagattct ggcgctagta
     9301 ccacaagact tgattaagcg aatcccgttt tttgtcagaa aacatgctac aacacgtacg
     9361 attaaacgca tttcaattga acaccctgaa ctctacgctg tagctcaaac aagtggtgag
     9421 attccagaaa aagaacgcga agaattgcgt cagattatca caactatctt tgaacaaaag
     9481 atgaataagc atagtattaa gtagagaatg aaaaaatatt ttattagcgg tttgggaagc
     9541 aatgcctatc atagcaagga tttttttcaa gaactagatt cgcaggtcta ttttctaaat
     9601 ccatatgaaa agcatcttcg agatgaaaca gaattgaaat catggtttaa aaatgagatt
     9661 gtagaggaag aatctatctg tctgataggt cattctcttg gaggagattt agctcgttat
     9721 ttcgcatcgg aatttgaaga agtaaagaaa ctgattcttt tggatggtgg ctatctagat
     9781 ttagataaga ttttaccttt ggatacagag ttagaggaaa ctaaaaatta tatcaaatct
     9841 caaattgttt tggacttaga tgttcttact tctaaagaaa aatctgaagc aaagcattgg
     9901 tcagaaaata tggagaaagc tgtaagacag tcctatcact ggaatgttga gtataataga
     9961 tatgagttgg ctataaatta tgaaaatata gaagctatac tccgcctacg gagaaaaata
    10021 caagctttta agagagaagt gggagatacc ttgtttatta gtcctcgcta tcctaatgga
    10081 gctacatgga gagaggaagc cctaaaagaa ttgccagact attttgatac tattttttta
    10141 gaaaactttg gccatgagct ttatactcaa gcacctaaag aaatctctag tctaatgaat
    10201 gagtggctcg cttattttct atgagctact tgtattgctg gaaatggtat aagatgaaaa
    10261 tctacaagtc actaattttt atataacaaa aaaacgaaca ggctcttttt ctgttattca
    10321 gaagagaact tgttcgtttt tatcttgatt ttcttaaaaa gctctatata catagggatt
    10381 ttctggttta tcgactttgg taaagctatc gatttccaag gtcgggagat tttgtttgag
    10441 ttctttatgg tagtgattga ccagttttcc tttggctgtt atccaagtgt tgttctcata
    10501 ttgacgggta tttcccttgg tcagcaaccc atagacacca gaatctgcga tgcagtgaat
    10561 aatgccgaag cggaacagaa attggctatt ggcatgactg gggtcattat agacaaagcc
    10621 tgtgaactgg attgtcttac cctcaaattc atctgaatag tcgtagatag cctccatgac
    10681 ttccatatag ttttcattag tgatctgaat actatcttgg gataagtatt tatccgccgc
    10741 cgttcgcatt tccttttcat aggctgattt tgaaaaataa gaactggtat ctggtttcaa
    10801 atattggctt gtcgtccctt cgcttgtctg aatggctaga tccgttcctt ccgatagggg
    10861 gaaatgataa cctttagcag aaacggtctg agaatccaag ctaacagttg ggaaagttaa
    10921 gccgatgaca agtggaatag ccagaagaga aatactcgtc atcttggcca atcggctgtt
    10981 tagatgactg tgggttttga cttgcttcat ccagatatac aattgaacaa ttgccaagat
    11041 aaaggaaagc accatggaga tataggccag ataggaatag tgcatgttga tgtactggtt
    11101 tagtttgccc gacagatgga ggtaaatagt cagttcaaaa tagccagcta aaactaaaaa
    11161 tcgaatcata ggatgactcc aatcaagaga gaataggata aaacgaccag agtcacaatc
    11221 gtaatgaagt gactaataaa tcgtgctttc aagtaatttt tcatcatgag aatatttttg
    11281 atatccagca ttgggccaat gacgagaaag gccagaactg gagccaaacc gaaactcgag
    11341 agtagagaag cacctataaa ggcatccgcc tcactacaga gcgaaagaag aaaggccaaa
    11401 agcatcaaga gcaggatggc aaaaagaggg gtcgcactga tagaggtcag aatccgagtc
    11461 ggaacgtaga cctgtattat agaagcaaag aggcagccaa ataccaaata acgccccgta
    11521 tcaaaaaatt catcaatggc ctgcacaaag acttgaaaaa ctttttttgc agaactcaag
    11581 taagaaaaat catgctcatg acaagccaga cgattttctt tctgaatcgg ttcttgccag
    11641 aaaaatccta gaaaaattcc tagtattaca gccacaagaa tggaacccag agctcgtaat
    11701 agggcgacat ggaaggagtt gccaaaggca gaataggtcg caaaaagaac aatgggattg
    11761 ataacaggtg ctgtcacaag aaaaggaacg gccgtgtaac ttggaacctt tttttccaga
    11821 aaacgattga tgatggggac gattccacat tcacaagaag ggaaaaacat accgacgaag
    11881 gtcccaaaaa agattctccc ccaacgattt cgagggagaa aatgataaac cttgtcaggt
    11941 gtgatataaa cttcaatcag ccctgagaca atacttccta tcagaacgaa gggaagggct
    12001 tcaatgataa tggagagaaa aatggctcca gtttgaagta cactagatgg gagttgttga
    12061 aaagcagtca tctagttttt cttttctgct ttggcttttt tctctttgtc atcagggaaa
    12121 gtgacttgtt tcaaatcagg gagtttagca aactcttcaa acatcttgtc caagtcgtct
    12181 cgttttgtaa atttgacagc cataggtgta cctcgattct agattctacc tctattatac
    12241 tattattttg cggaaaaggg aaaagttaaa atttcaaatt gagtagctaa gagataatat
    12301 agcttgatat tacctgatat atatcataat tgtgctataa ttaaataaaa agaaaatcat
    12361 tatcagaaaa ttatgggagg tagtcaaact gacttactca attagtgttg ttttgttaca
    12421 tcaaggagat aaaaatagtt tattagagtc tttgtcaata gtggagagac aaacattaaa
    12481 agatatagaa gttattattg taaatcaatc tacagaggag atagcttcca ttagccaaca
    12541 gatgaatcta tcatttaata ttaagattat agatgagaat tcttttgctg agttgtctga
    12601 tatgattaca ggagattata ttacgtttct atcttcaaat gattcattat ttgattggac
    12661 atttgaaaag atgtatcatg cgataaaatt atccgattct gatgttgttc ttggtcattt
    12721 tgctgatttg gttgatggag tattttactt ttatccttgg gggggataat tggttgacag
    12781 aaaatttaac gaatgttcaa gttttacaaa agatggatga tacagatcat cgaattagaa
    12841 aacaatatcg ctcattattt ggaaaattat tcaatagtaa gcttttacga aaaataaatc
    12901 aatttgatat aaacaacctt atttggagac tttatattca ctctaaaact gcaacctata
    12961 ttaatttccc gacatatatc tataaacctg ttatagatgc taaacctcta aaagactcct
    13021 acaaaatcat attagaaaat tatgaaaata gaatcaaaga ttgcgccgtc ttagaaaact
    13081 atgatataga aagagcgaaa aaacaatata ttcaagaatt ggcaaatttt agtgcttggt
    13141 taaaaaatga cggtgaatat ttagattctg atattgttta tcataagtta atagctgcag
    13201 agaaaggaat tttccctttt cttgagcttg atagattaga ttttacgatt ataagtaata
    13261 attgtgttgg aggattaatt tataaacagc ttggttttca atatagaaca ccttttgttg
    13321 gtttatttat tcttcctgat gattattata aacttacaaa gcattttcgt tattatatgg
    13381 aacaagaact tgttttcgaa gaggaactta tttcaccgaa ctggactcat gaagtttatc
    13441 ctttggggca cttaggagat atagatattc attttctaca ttattctagt attgaagaag
    13501 cacgaactaa gtgggaaaaa agaaaaaaac gcataaattg gaataatctt tattttaaat
    13561 ttgataataa agattcagct agtgaagaaa ttttaaataa gatggataat cttccttatt
    13621 ctaataaatt aattttagtc aatcgtccat ataaaaattt gaaaagtcaa tgtgttattc
    13681 caggtcagga acatcttcca gaactggcta ttatgtctga tccattaaat acttttgata
    13741 tcatggcttg gttaaaaaaa ggtggcaatg ctctttaagt gcaagttatt gcgctgtagc
    13801 atataaatct atttcctaca tattttttaa atgttctacg agttaatttg aaacgtttag
    13861 cttgtggtat aatagattta tggataaaaa atatgaaaaa atctctcagg atttgggagt
    13921 gacgttaaag caaattgata ccgttctaag tttgacagct gaaggggcga ctattccctt
    13981 tatcgcgcgt tatcgcaagg acatgactgg tagtctggat gaggtggcga ttaaggctat
    14041 tattgatttg gataaaagtc tgacaaatct caatgaccgt aaggaagctg tcttagctaa
    14101 gattcaagaa caaggtaagt tgaccaagga attggaagaa gctatcttag ttgccgaaaa
    14161 attagcagac gttgaagaac tctatcttcc ttataaggaa aagcgtagta ccaaggcaac
    14221 cattgcccgt gaagctggac tctttcctct tgctcgcttg attttgcaga atatagttga
    14281 cttagagaaa gaagctgaaa agttcgtctg tgaaggattt gcgactggca aggaagcctt
    14341 gaccggtgca gttgatattt tggtcgaagc cttatcggaa gatgtgacct tgcgttctat
    14401 gacttatcag gaagtgctga gacactctaa actcacttct caagccaagg atgaaagtct
    14461 tgatgaaaag caggtttttc agatttatta tgatttttca gagacagttg gaactatgca
    14521 aggctatcgt accttggctc tcaatcgtgg ggagaaactt ggtgtcttga agatcggttt
    14581 tgaacatgcg acggaccgta ttcttgcctt ctttgctact cgtttcaagg tgaaaaatgc
    14641 ttatattgat gaagttgttc agcaatccgt taagaaaaag gtcttgcctg ctattgagcg
    14701 tcgtattcgg acagaattaa ctgagaaagc tgaagaggga gctatccaac ttttttctga
    14761 caatctgcgc aatctcctct tggttgctcc actgaaaggg cgcgtggttc ttgggtttga
    14821 cccagccttt cgtacaggtg ccaagctagc tgtcgtggat gcaacaggaa aaatgctgac
    14881 aactcaggtt atttatcctg ttaaaccagc atcagctcgt caaatcgaag aagccaagaa
    14941 agatttagca gatttaattg gtcaatacgg tgtagagatt attgccattg gaaatggaac
    15001 ggccagtcgt gaaagtgaag cttttgtagc ggaagttctg aaagatttcc ctgaagtcag
    15061 ctatgttatc gttaatgaaa gtggtgcttc tgtctattct gccagcgaac ttgctcgtca
    15121 ggagtttcca gacttgaccg ttgaaaaacg ctctgccatt tctatcgccc gtcgtttgca
    15181 agatcctctt gcggaattgg tcaaaatcga tcctaagtca attggtgtcg gtcaatacca
    15241 acacgatgtc agtcagaaga aactatctga gagtctggac tttgttgtcg atacagtggt
    15301 taaccaagtt ggtgtcaatg tcaatacagc tagcccagct cttctttcac acgtagctgg
    15361 actcaataaa accatttctg aaaatatcgt caaataccgt gaggaagagg gaaaaatcac
    15421 ttcacgctcc caaatcaaga aagttcctcg tttgggggcc aaggcttttg aacaggctgc
    15481 tggtttcctc cgtatccctg aaagtagcaa tatccttgat aatacaggag ttcacccaga
    15541 aaattacgct gccgttaagg aactcttcaa atgcttggac attaatgatc tgaatgaaga
    15601 ggcccaaagc aaactcaagt cgctttcagt caaggaaatg gcgcaagagt tagaccttgg
    15661 tccagaaact cttaaagata tcattgcaga tcttctcaaa ccaggtcgag atttccgtga
    15721 ttcctttgat gctccagttc tccgtcaaga tgtcctagat atcaaggact tagtggttgg
    15781 acaaaagcta gaaggagtgg tgcgtaacgt tgttgatttc ggtgcttttg ttgatatcgg
    15841 aattcatgag gacggtctca tccatatttc ccatatgagt cgcaagttta tcaaacaccc
    15901 tagtcaagtg gtggcagttg gagatttggt gagcgtttgg gttaagaaaa ttgatactga
    15961 acgtgaaaaa gttaatctgt ctctcctagc tccaaatgaa actgactgat tacgtcaagc
    16021 aggtttcact agaagacttc ggcagacctt ttatccatca tgtccagtgg aataggcgtc
    16081 tacgttcgac aggtgggcga tttttcccca aagatgggca tttggatttt aatcccaagg
    16141 tttatcagga actggggttg gacgttttta ggaaaattgt ccgacatgaa ctctgtcatt
    16201 atcacctcta ttttcaaggg aaaggctatc aacacaagga tcgggatttt aaggaactgt
    16261 tgaaagcagt ggatggatta cggtttgtac catccttgcc caatagtaac tccaagccaa
    16321 tcaagctcta tcgttgccaa tcctgccagc aaacttatca gcgcaagcga agaattgata
    16381 ccagacgcta tcgctgtgga ctttgtcgag gtaaattgct actaataaat cagcctgagg
    16441 actgatgaaa gccgagccta cccgtgatat actatgtcta acctagcaga aagaggaaat
    16501 atcatgaaca gtaaatttta taaaatgaga cgaaatcgca tgatttcagg agttttggca
    16561 ggtctgtcag acaagtggaa ctttgatgtt acccttgtac gttttctgtt tgccattttt
    16621 acagtcgcaa actttggact tggggtgatt atctatatca tcctagcttc tatcatgcca
    16681 accaaggaag aaatcgaagc agaaatgtac ggaacaggcc cacgtaaacg caaagaagct
    16741 caagccattg acgataatga aggctggttt tggtgaggtt ttacaaaaga tttggaatac
    16801 gcaaaaagct ttaaatcaat agtctaaact gcttgattta aagctttttt acttttatac
    16861 tcaataaaaa tcaaagtgca aactaggaag ccagccgcag gctgtaattt agtcggcaat
    16921 gtgaagttga tatagtttgc actttgattt ttgaatagta ttaataatat ttcgccagct
    16981 tcatccacaa actatagtgg attggaacta gaataggaca cctatactta taaaaaattg
    17041 ttagaaatcg atttgactat cctgatcgat ctgtcctgtt cttatttcat tttactataa
    17101 aagcagtaat ttaaacgcag ttttttaatc tatttttgct gctgagacaa tacatttttg
    17161 gaaaaatggt ggatgctgat aacaactgat aaccagcaaa taacataagc agtgccggta
    17221 aattctgtac cgataaagtg tgtgtgttca actaagagct gaccgatgaa tggagagagc
    17281 agatagagaa gtccgatgag tatatgttct ttgtgtttca ttaaagcgca ccttctttcc
    17341 ttataggttg aacgacttgc aagtgttaaa ttgaatggta tgttatctag gtaaccttac
    17401 taaaatgtta gttcccgctt cctccttttc aaagtaagcc ttttcacact tatattttac
    17461 aactttaaaa ataggaaatc aaatcatttt ctaagtaatt ttgcttatat ttcacccaat
    17521 cttacaaaaa tgtaagatta aagtctcttt tgtaaggtta ggttatggca agcggtcttt
    17581 ttttgatgta aactagactc ataaagaaca aaggagtaac atcatgaaac aaatcttaca
    17641 taagaaaact agaaaaccaa gtcacaaaga aattgagcgc gttcagctgg gatgcactat
    17701 gatgcaagct acatttcatt tgatgggata ttaagaaagg agattctcat gacactttta
    17761 gatgtaaaac acgttcaaaa aatttataaa acacgttttc agggcaacca agtagaagcc
    17821 ctcaaggata ttcactttac cgtcgaaaag ggtgactacg ttgccatcat gggtgagtct
    17881 ggttctggta aatcaactct tctcaatatt ctagctatgc tggataaacc aagtcgtggt
    17941 caggtttact tgaatggaac tgacaccgca accattaaaa attcacaggc ctctagcttc
    18001 cgtcgtgaaa agttgggctt tgtcttccaa gactttaact tgctagatac tctatctgta
    18061 aaggacaata tcttgcttcc gcttgtcttg tcaagaagac ctattacaga gatgatgaag
    18121 aaattggtgg tgacagctga gaatctggga ataaaccaat tacaagagaa gtacccttac
    18181 gagatttctg gtggccagaa acagcgtgta gcagtagcac gcgccatcat cactgaacct
    18241 gaaattctcc ttgcggacga accgacagga gctcttgact ccaagtcatc tgcagcctta
    18301 cttgatgtct ttgatgaaat caatgagcgc ggccaaacca ttctcatggt aacccactca
    18361 acagtagcag ctagcagagc taaacgtgta ctctttatca aagacggcat tctttacaat
    18421 caaatctacc gtggagagaa gacagaacgt cagatgttcc aagaaatctc tgataccttg
    18481 actgtcatgg caagcgaggt gaattagtat gtttcgatta accaataagt tagcggtatc
    18541 gaacttgatt aaaaaccgca aactctacta tccttttgcg ctggctgttc tcttggcagt
    18601 cactgtcacc tatctctttt actccctaac cttcaatcct aagattgcgg aaatccgtgg
    18661 aggaacaacc attcaggcta cacttggatt tggtatgttt gtcgtcaccc ttgcgtcagc
    18721 cattatcgtt ctctatgcca atagttttgt catgaagaac cgttccaagg aactaggaat
    18781 ttatggcatg ttgggcttgg agaagcgtca tcttatcagt atgaccttta aggagttagt
    18841 ggtatttggg attctaactg ttggagcggg tatcggtatt ggagccttgt ttgacaagtt
    18901 aattttcgct ttcctgctca aactaatgaa attgaaggtt gagctggttg ctaccttcca
    18961 gacgaaagtt gtcattacag tgcttgttgt cttcggtttg attttcctag gtctcatgtt
    19021 cctgaatgcc cttcgaatcg cccgtatgaa tgccctccag ctctctcgtg agaaagctag
    19081 tggagagaaa aaaggtcgct tccttcctct ccaaaccatt cttggttcca taagtttagg
    19141 aattggctat tatcttgccc ttacggtaaa agatcctctt acagccttaa caaccttctt
    19201 catagctgtt ttactggtta tctttgggac ttatctcttg tttaatgcag ggattaccgt
    19261 tttcctccaa atcttaaaga aaaataagaa atactattac caaccaaata atctcatatc
    19321 tgtttctaac ttgattttcc gtatgaagaa aaatgcagtt ggactagcca ccatcgctat
    19381 cttgtcaaca atggttttgg taaccatgtc agcagcgaca agcattttca attcctcaga
    19441 aagctttaaa aaagttctaa atcctcatga ttttggggtt tcagggcaaa atgttgaaaa
    19501 agaagacttg gacaaactct tgagccagtt tgcaagtgac aaaggttata agattaaaga
    19561 aaaagaagta tttcgttaca cttactttgc tgttgcgaat caagaaggaa ccaagttaac
    19621 tatttttgaa aaaggacaaa accgtgtcca accaaaaaca gttttcatgg tatttgacca
    19681 aaaagattat gaaaatatga ctggtcaaaa actgtctcta tcaggaaatg aggtcggtct
    19741 ctttgccaaa aatgacggac tgaaaggaca gaaagctcta actctaaatg atcatcaatt
    19801 ttctgtcaaa gaagaattta ataaagattt cattgtcaac catgttccaa ataagtttaa
    19861 tatcttgact actgattaca attaccttgt tgttcctgat ttacaagcct ttttggatca
    19921 attcccagat tcggctatct ataatcagtt ttacggtggt atgaatgtag atgccagcga
    19981 agaagaacaa ctcaaggtcg ctgaggagta tgaaaactac ctcaatcaat ttaatgctca
    20041 attagacaca gaaggtagct atgtttatgg tagcaatcta gcagatgcta gttctcagat
    20101 gagtgccctc tttggtggtg tcttctttat cggtattttc ctatccatta tctttatggt
    20161 cggaactgtt ctggtcatct actacaaaca aatttctgaa ggctacgaag accgtgaacg
    20221 ctttattatc ttgcagaaag tcggtttgga ccaaaagcaa atcaagcaaa ccatcaacaa
    20281 acaggtttta actgttttct tccttccttt gctctttgcc ttcatacatc tcgcctttgc
    20341 ctaccatatg cttagcctga ttttaaaagt gattggtgta ctggatacga ctatgatgtt
    20401 gattgtgacc ttgtctatct gcgctatctt cctcatcgcc tatgtgctga ttttcatgat
    20461 tacttcaaga agttatcgca agattgtgca aatgtaaaaa agatacctcg acttcaaaat
    20521 cgaggtattt cttgtattct aaatgctgaa aagttgttcg agcaggaagg taacgcccat
    20581 ggtcaagaga ccaatagcaa ggttccgaat catagctgtt ttggttgggg cttttccaag
    20641 tctagcactt gtgtaaccag tgagaagaag ggccacaccg acaataagga cggtagcagg
    20701 gatgcggtaa tcacttggaa aaatggtcac tgacagcatt ggaggcaaac ttctaaggaa
    20761 aaaggcaacg aagctagaaa tggcagcgtg ccaaggattg gtaaattctt catactcaat
    20821 cccatatttt tcctctacca gagccttgag tggattttta agaaagatct tattggtcaa
    20881 gagttgggca gaagttttga attctccatt ttggatataa gcagcataga gggatttttt
    20941 ggctagttcc ctatcttggt ctagcaagag tttttctcgc gaaacggcag cttcctcggt
    21001 atcttttgga gttgaaacgg atacatattc tccaccagcc attgaaaagg caccagctaa
    21061 gatagccgta aaacctgata aaaagataat ccagatattg gtcgtggcac tggcaactcc
    21121 gataaccaca ccagcaatgg aaataattcc atcgttagca tcaagaacac ccgcacgcag
    21181 gatatttaaa cgacctgcaa aatttgaatc aatttcgtga tttgtttctg acgctaaatt
    21241 tcaagttcaa gttagccatc cagaagtctt ctctgggtga cttgtagtcc aagcattttt
    21301 taggatagtt gttaatccac ttttcgatga atgcgacttc tttgggagtc attttcttgg
    21361 ttcccttagg taaccatcta cgaatgagcc tgttgtgatt ctcattagtt cccctttccc
    21421 aagaggcata ggggtgcgca taatagatgt gctcctcaga aaatacatca aacaagcgat
    21481 tgaattccgt tccattatct gccgtgatgg aaagaatctt gtgttgtttt aagatgagtt
    21541 ttagagcctg attgaccacc tcagcacttt tatttggaat caatcggatg atctgatgtc
    21601 tactctttcg atccgtcaag acaagcaagc agtagttttt cgctctcgta agtagaaccg
    21661 tatcaatctc ataatgccca ttctccaagc gaagattgat agcttcagac cgctgttcga
    21721 tggattgacc agcaggttta aagttggtgc tagcctgttt cttatcaggc gaaaattttt
    21781 ggttatgata gtggagaatc ttttccttta gttccttggt caagcttgat ttcttgaccg
    21841 agcgcttgcg attgttttca taagactgtt gagcatagtc ggcagaataa acctctttga
    21901 agcgcccttt tccaagacat tgtcggactg tcccacgctt gatttcagtg tggatagttt
    21961 gaggagcttt tccaagtaga gaggcaattt ctctatttga ttttccttct tttttccatc
    22021 tttcgattaa gcgacggcta tcgattgtca aatgtttacc ttttgtagta taattgtctt
    22081 gcatttctgt gcctttcttg tgtttgtggt tgaacaacaa gtataacaca gaggtgtttt
    22141 cttatgccta caagagctat cagctagttg aaccatctaa tttttaggag ggctgggtgg
    22201 ctaacttcat tatagaactt tcatttacga acatatagta aaatgaaaca agaacagaac
    22261 aaatcgatca ggacagtaaa atctatttct aataatgttt tagaagcaga ggtgtactat
    22321 tctagtttca atctattata tttttgtttt ttatcaaaaa atactttaca agttcttaaa
    22381 aacatgatat agtaataaag cttagaaaat gagatgatgt tttctagcaa atataaaccc
    22441 gagtaaaaaa tgcctacgga caggcagggt tgaatgccga agcgtggttg aaaagccaca
    22501 ttattgatag ggttaaaagc ctacttttat aagttgatgt taggacactt gtcctaattc
    22561 ataaattttt agtgtggtga aagcacacgt catcttgtga aacgatcaat aaagtacgta
    22621 atatttgcta ctagagagtt aggaaacatc gggaacagac atactcaaca gaaaccaaaa
    22681 taaacacgtc agaagattgc agagcaggtg aaaacctgct cttttttcat gagtcaacct
    22741 ttagttcctt agttttcata aggtcctaaa aatattgaaa ggagtatgtt ttgaaagagt
    22801 tagatcaaaa ccaagcccca atttatgaag ccttggtgaa gttacgcaag aaaaggattg
    22861 ttccctttga tgttccaggt cacaagcgtg gacggggaaa tccagaactt gtcgaactct
    22921 taggagaaaa atgtgtaggc attgatgtca attcgatgaa acccttggat aatttaggcc
    22981 atcctatttc gattattcgt gatgcagagg agctggctgc agatgctttt ggagctagcc
    23041 atgcctttct aatgattggt ggaacaactt catcggtgca gactatgatt ctggcaacct
    23101 gcaaggcagg agataagatt attctgccac gaaatgtcca taaatctgct atcaatgcgt
    23161 tggttctatg tggtgccatt cccatctata tcgagatgag tgtagatcct aagattggta
    23221 tcgctttagg tcttgaaaat gaccgagtag cacaggccat aaaggaccat ccagatgcta
    23281 aggctatcct aatcaacaat cctacttact acggcatctg ttcagaccta aaggggttga
    23341 cagaaatggc tcatgaagct ggcatgatgg ttttagtaga tgaagcccat ggagcgcatt
    23401 tgcatttcac tggtaaactt ccaatttctg ctatggatgc aggagctgat atggcagcag
    23461 tttccatgca taagtctggt gggagtttga cacaaagttc gcttctttta atcggggagc
    23521 agatgaatcc cgagtacgtt cgtcagatta taaacctgac ccagtctaca tctgcctctt
    23581 acttgttgat ggctagtttg gatatttcac gtcgcaactt ggcccttcgt ggtaaagagt
    23641 cgtttgagaa agtcattgag ctatctgagt atgcccgccg tgaaatcaat gctatcggtg
    23701 gctactatgc ctactcaaaa gaattaatag acggtgtttc ggtttgcgat tttgacgtaa
    23761 ctaagctgtc agtttacact cagggtattg gcttaacagg tatcgaggtt tatgacctct
    23821 tgcgagacga atacgacatt cagatcgagt ttggtgatat cggcaatatc ttggcctata
    23881 tttctatcgg cgaccgcatc caagacatcg agcgcttggt tggtgctctg gctgatatta
    23941 agagactcta ttcaagagat ggaaaagatt tgatagcagg agaatatatt cagcccgagt
    24001 tagtgctgtc tccgcaagaa gccttctatt cagcaagaaa aagtttaact ttggatgatt
    24061 ctgttggaca ggtctgtgga gaatttgtca tgtgctatcc tccaggtatt cctatcttgg
    24121 ctcctggtga acgcattaca cgagaaattg tcgactatat ccaattcgcc aaggaacgtg
    24181 gttgctccct ccaagggacg gaagatccag aggtcaatca tatcaacgtt attaagagaa
    24241 agacaaacta taagaaaagt caatagttta tctaaactat ttcttatttc aatttgatga
    24301 tttggcgatg attttagagc acggcaaaaa gcccttgaat tagaagcggt caatcgctta
    24361 atttctatca gcttatcaaa tcctgcctca atccttttct gaggattagg gtagcgtgtc
    24421 aagagttggt aggtatattc tgaatgcttt ccaacgattt tatccaactc aggaaagatg
    24481 atatcaaggc aacgagtgta ttgtactttc caatcagact gttttttctt gagacgatga
    24541 atatgtctag tcagtatttt tagttctact tgccgattat tgtgttgaaa ttgttcacga
    24601 ttggggtcag aaagaagttt aagagcgatg ccatgagcgt ctttcttatc cgttttagtc
    24661 ttgcgaagtg ataatgattt ggcaaatttc ttgatgagca aaggattgta ggtgtaaact
    24721 ttatatcctt gttcatgcag gaagttcagt agattaaagg cataatgtcc agtatcttca
    24781 agagcgatga gacagtcttg gttgagctgt cgaagagaca gatctaagag ttcaaaacca
    24841 gctttattat ttgaaaaagt gagtggttta agaacagttt ttccttgaac attcaaggct
    24901 gtaacatcgt gtttattttt agcgacatca atgcccacat aaagcatggg agtacctcca
    24961 gatgtagtat ttcaagtcta cttggttatc cacgaacttt ttgccttgtt accttagacg
    25021 agataaaacg tctatgcgtt atcaaactca ttaccaattg aaacaaaaag ctgtggttag
    25081 atcctttcgg aaatcgtcaa gcgattggag gaaatgaact aatccacagt ggcttattcc
    25141 aagtatacca cttgggcttt ggcagtagct aactgcgcta aatataatat aaggagaaat
    25201 agatggattt atggttttct gaagttcata ctccagatgt caaattgtct ctgagaacag
    25261 ccaagcaact ttacgctgga aaaagtgaat ggcaggatat cgaagtcttg gatacgccag
    25321 cttttgggaa aatactgatt ttaaatggcc atgtcttgtt ctcagatgcg gatgatttcg
    25381 tctacaatga aatgaccgtt cacgttccca tggctgtcca cccaaatcca aagaaagtat
    25441 tggttattgg gggtggtgac ggcggtgttg cccaagtatt aacactctat cctgaactgg
    25501 aacaaatcga tatcgtggaa ccggatgaga tgttggtcga ggtctgtcgt gagtatttcc
    25561 cagactttgc tgcagggcta gatgatcctc gtgttaccat ttactaccaa aatgggctac
    25621 gctttttgcg aaactgcgaa gatgattacg atattatcat caacgatgcg acagatccat
    25681 ttggccatac ggaaggactc tttaccaagg aattctacgg caatagttat cgagctctga
    25741 aggaagacgg catcatgatt taccagcatg ggagtccctt ctttgacgag gatgagtcgg
    25801 cctgccgaag catgcaccgc aaggtcaatc aagcctttcc aatcagtcgg gtttatcagg
    25861 cccatattcc aactagccca gctggctatt ggttgtttgg atttgcatcg aaaaaatacc
    25921 accctgtcaa agattttgac aaggaaggct ggaaaaaacg ccagcttttc acagaatact
    25981 acactgcaaa cttacacgtg ggagccttta tgttgcccaa gtatgttgag gacattttag
    26041 aagaagagga aggaaaaaaa tgagtcgttt actagttatt ggttgtgggg gcgttgccca
    26101 agttgctatt tcaaagattt gtcaagatag cgaaacattt acagagatta tgattgctag
    26161 ccgtaccaag tcaaaatgcg atgacttgaa agcgaagcta gaaggcaaaa caagtactaa
    26221 aattgaaact gcagcacttg atgctgacaa ggttgaagaa gtgattgccc tgattggaag
    26281 ctacaaacca gaagctgttt tgaatgtagc tctgccttat caagatttaa ccattatgga
    26341 tgcttgtttg gcaacaggtg ttcactatat cgatacagcc aactacgaag cagaagacac
    26401 agaagaccct gagtggcgtg ctatctacga aaaacgttgt aaggaacttg gttttacagc
    26461 ctactttgac tactcatggc agtgggctta tcaagagaaa ttcaaagaag caggcttgac
    26521 tgctcttctt ggttctggtt ttgacccagg tgtaactagt gtcttttcag cttatgccct
    26581 caaacactat tttgatgaaa tccattatat cgacatttta gactgtaatg gcggtgacca
    26641 cggttatcca tttgcaacca actttaatcc agaaattaat ctccgtgagg tttctgcgcc
    26701 aggttcttac tgggaagatg ggaaatgggt cgaagtcgaa gctatgtcta tcaagcgtga
    26761 gtatgatttc cctcaagttg gacaaaaaga tatgtatctc cttcaccatg aagaaatcga
    26821 atcattggcc aagaacattc caggtgtcaa acgcattcgt ttctttatga cttttggtca
    26881 atcttacttg acgcacatga aatgtcttga aaatgttgga ctccttcgta cggataccat
    26941 taactttaac ggccaagaaa ttgttccaat tcaatttttg aaagccttgc ttccagatcc
    27001 tgctagcctt ggcccacgta cagtcggaaa aaccaatatt ggatgtatct ttacaggtgt
    27061 caaagatggc gttgaaaaga ctatctacat ctacaatgtt tgcgaccatc aagagtgcta
    27121 tgcagaagtc gggtcacaag caatttcata cacgacaggc gttccagcca tgattgggac
    27181 aaaattagtc atgaacggaa cttggaaaca agctggagtg tataaccttg aggagttaga
    27241 tccagatcca ttcatggaag ctttgaatga gtatggtttg ccatgggttg tggttgaaaa
    27301 tccacaaatg gtggactaat gaagttagaa caagtaccaa caccagccta tgttattgac
    27361 ttggccaagt tagaagctaa ttgccgcatt ctacaatatg tacaagaaga ggccggttgc
    27421 aaggtcttgc ttgcccagaa ggcatattcc ctctacaaaa cttatccctt gattagccag
    27481 tatctatcag gtacgacagc tagtggactc tatgaggcca aattggcaag ggaagaattt
    27541 cctggtgaag tccatgtttt tgcaccagct ttcaaggatg aggacatgga ggaattgctt
    27601 gggataacag accatatcgt ctttaactca gagagacagt tgcgtaagca tggggctcgt
    27661 tgtcgagagg ctggtgtcag tgttggtttg cgcctcaacc ctcagtgttc aactcaagga
    27721 gatcacgcgc tctatgaccc ttgtgcacct ggttctcgct ttggagttac tatagacaag
    27781 attccgagtg atttgctaga tttggttgac ggacttcatt ttcataccct ttgcgagcag
    27841 ggagcagatg atttacaaac aactttgaaa gcagtagaag aacagtttgg tccctactta
    27901 catgaggtaa aatggctcaa tatgggtggt ggtcatcata ttacaagaga aggttacgat
    27961 gtggatttgc tgatttcaga aatcaagcgt atccgaaaaa cttacaatct tgaaatctat
    28021 atcgagcctg gtgaagccat tgcgcttaat gcgggttatt tagcaactga ggtattagat
    28081 attgtagaaa acggtatgga aatcttggtt ttagacgcct ctgcgacctg ccatatgcct
    28141 gatgtacttg agatgcccta tcgtccacct ttgagaaatg gctttgagtc acaggaaaaa
    28201 gcccatacct acagactttc ttctaatacc tgtctgactg gcgatgtgat tggtgattat
    28261 agttttgaaa atccagtcca aatcggagac agactttatt ttcaagacat ggccatttat
    28321 tcttttgtca aaaataatac ctttaatggt attggattgc caagtctcta tctcatggac
    28381 gaacagggag actgtagctt actcaaagct tttggctatc aagactttaa agggagatta
    28441 tcatgatgga cagtccaaaa aaattaggct atcacatgcc agcagagtac gaaccccatc
    28501 atggtaccct catgatatgg ccgactcgac caggatcatg gccttttcaa ggaaaggctg
    28561 ctaaaagagc atttactcag atcatcgaga ccatagcaga aggggaaaga gtctatcttt
    28621 tggtggagca ggcctatcta tctgaagccc aatcctatct tggagacaag gttgtttatt
    28681 tagacattcc caccaatgat gcctgggcgc gtgatactgg cccaaccatt ctcgtcaatg
    28741 ataaaggtaa gaaattagcc gtggattggg cctttaatgc ttggggaggc acctatgatg
    28801 gtctttatca agattatgaa gaggatgacc aagtagccag tcgttttgct gaggccttgg
    28861 aaaggcctgt ctatgatgct aaaccttttg tactggaagg aggcgcaatc catagcgatg
    28921 gtcaaggaac tattctcgta actgaaagtt gcttgcttag tcctggtcgc aatcctaact
    28981 tgactaaaga ggagattgaa aacacattat tagaaagtct tggtgctgaa aaagttattt
    29041 ggcttcctta tggtatttat caggatgaaa ccaatgaaca cgtcgataat gttgttgcct
    29101 ttgttggtcc tgctgaggtt gttttggctt ggacagatga cgaaaatgat ccccagtatg
    29161 ccatgtcaaa agcagatctc gaactcttag aacaggaaac agatgcaaaa ggttgtcact
    29221 tcaccattca taaattgcct atccctgcag ttcgacaagt tgtgacagaa gaagatttgc
    29281 caggctacat ctatgaagaa ggagaagaag agcgatacgc aggtgaacga ctagcagctt
    29341 cctacgtaaa cttttatatc gccaacaagg ctgtcttggt tccacagttt gaggatgtaa
    29401 acgaccaagt ggccttagat atcctcagca agtgtttccc agaccgtaaa gttgtcggaa
    29461 taccagccag agatattctc ttaggtggtg gcaatatcca ctgtatcacc caacaaattc
    29521 cagaatagga gaaaaagatg agaaatgtaa gagttgcaac cattcagatg caatgcgcta
    29581 aggatgtggc aacaaatatc caaaccgcag agcgtttagt acgtcaggct gctgagcaag
    29641 gagcccaaat tattctcttg cccgagttgt ttgaacatcc ctatttctgt caggaacgtc
    29701 agtatgacta ctaccagtat gcccaatctg tagcggaaaa tactgccatt cagcatttta
    29761 aggtgattgc taaggaacta caagttgttt taccaatcag tttctatgaa aaagatggta
    29821 atgtcttgta taactctatt gccgtcattg atgcagatgg ggaagtgctg ggcgtttatc
    29881 gaaagaccca tataccagat gaccattatt atcaagaaaa attctatttc acgcctggta
    29941 acactggttt caaggtctgg aatactcgct atgctaagat tggtatcggt atctgttggg
    30001 atcaatggtt ccctgaaaca gcgcgctgtc ttgcattgaa tggtgctgaa ttgctctttt
    30061 atcctacagc tatcggttca gagccaattt tggatacaga tagttgtggt cactggcaac
    30121 gtactatgca agggcacgca gcagcgaata ttgttccagt catcgcagcc aatcgttatg
    30181 gtttagagga ggttactcct agtgaggaaa atggcggaca gagttccagt cttgacttct
    30241 acggttcctc ctttatgacg gatgaaacag gagctattct agaacgagct gaaagacaag
    30301 aagaagctgt tctgttagct acttataacc tagacaaggg agcaagtgaa cgcctaaact
    30361 ggggcttgtt tcgagataga agaccagaaa tgtatagaca aattacagat tagtgtggga
    30421 gaaatgagag attcattctg ctagactaac ttcttattag caactataag atactatggc
    30481 atctagtaaa tcgattttta tgattcgcta ttcttctcta ttgattagtc cgtattttaa
    30541 aatattagca aaaaagcaaa tagcagtaac ttctgtctat ttgcttttct tttttataga
    30601 atatatttct caatagcacg cgcaacgccg tcttcttcgt tgcttgaggt aacggcatcc
    30661 gcaagagatt tgacataatc gctggcattt cccattgcaa tcccaagccc tgcaaactgg
    30721 agcatttcga tatcgttatt agcatcgccc atggccataa tctctgagga atcaatcttc
    30781 aaaatctcag ctagtcgtga aagagcagta gcctttgtcg ttccaagtgg cattgcttca
    30841 taaatgacag gctgcgaacg aactccactg aatcgttggc aaagctcttc agcaaaacgc
    30901 tgctcaaaat cgtctgtttg ttcttttgtt cctaaaaaca taccttggaa catccggaac
    30961 tttccactag tcgcttcctc aagagaaatt tcagtcaggt ctgaaaatac tagtttagca
    31021 tcattttcaa taacttgatt gggctttcca ccgagaacaa aataatgtga ctcgtcaaaa
    31081 agtgtcaact gaacatcact cttttcagca aggtcataga ggtattcgat gtcagctgga
    31141 ctaagttctt gccagtcaac caagccccag tcgctagtct ggtgagttga acaaccgttg
    31201 ttaacaatca catactcatt ctggaggtcg agtcccagtt ttttgtagta ggggaggaca
    31261 ccgaaaaggg ggcgacccgt acagagaacc agtttgacac ctttttcaat ggctttgtga
    31321 atagcagtaa tgtgagcttg tgggatttcc ttggcttcat tgaggagggt gccgtccata
    31381 tccaaggcta gtagtttaat cataggtctt ccttctttat cttttgctat tattatagca
    31441 tattttggag aagaaattga tagaaagctt gagactaatt gattttatag tttaagatgt
    31501 tttgatgaca actcatgatt tgaagaggat atttcgcaaa gatatgctat actatgtttg
    31561 tcaatgttgc aactagacaa attaaaaaac caacttaata taatagtttt tttgtaagta
    31621 ggtatgagta tcagattact caactaatct gaagaataat ggaggaaata tatcatgatt
    31681 ttaatgacaa aaaatataaa tctaacaaat gaagaattag agctgataca aggtggagca
    31741 gattcatatg gtaaaaatcc taatggtagg tacgattggg aaatagaacc agtattaact
    31801 ctgccggttc atggattttg tcccagaggc acctatgatt taggatatat tggaggaggc
    31861 aatcatcttt gcaaaggaag tgctgcgaga ttttaagtaa aatttattag taatatgaag
    31921 aaacaagggg agaaagcaga gaatttaata tgaaaaaacg ggctattcaa attttactag
    31981 cattgtcctt aattttttac aaatcaactt ggttttggag agttttcaat cacctcgcaa
    32041 agccctatct accagcaagt cgtgaatttt ttcagattct gcttttgatg gagagcggag
    32101 ttcttttctt agcggtcatc tatctactgg tttttgcagg aaagaaaatt tttcatttca
    32161 agtggcagct gaggtacttc atctaccttt tactgggcta catcatttca tatatgtctg
    32221 acttcctctt ttcgtatttc atatccctgt cttcaaatca gatttctttg aatgaaacga
    32281 tagaaatgat ggggagacag gagttccctt atttcttgct catcgtttgc ttcatcgccc
    32341 ctattgctga ggaattgatt tatcgaggtg tgcttatgac aacctttttc aaaaactcac
    32401 cttggtacgg agatgttttg ctttctgcta ttattttcgg ttatattcat atcaattttg
    32461 ctttaactcc tcttgctttt ttcatttatg ctagtggagg tctgatttta gctctattgt
    32521 atcgcatgac taaaaatctc tactatccaa tactagttca tattctcatc aatatcactg
    32581 ccttctggga tgtttggtta ctcctatttt caggaagtta gcttactaaa aaaatgtcgg
    32641 aattttccgg cattttcttt tttcacaaat agtcaacgtt tttctttccg atactgaagt
    32701 ggtgtgtagc cacttatttt tttgaattga ttttgaaaat aagattggcg tgagaaaggc
    32761 agatagtgaa gatagttaag aagaatagga tgttcttttt tcctttttgg aaaacttcta
    32821 aaatatggta taatgaaaag ataaagaagt tgggggtaga agatgaacat tcaacaatta
    32881 cgctatgttg tggctattgc caatagtggt acttttcgtg aagctgctga aaagatgtat
    32941 gttagtcagc cgagtctgtc tatttctgtt cgtgatttgg aaaaagagtt gggctttaag
    33001 attttccgtc ggaccagctc agggactttc ttgacccgtc gtgggatgga attttatgaa
    33061 aaagcgcaag aattggttaa aggatttgat atttttcaaa atcagtatgc caatcctgaa
    33121 gaagaaaaag atgaattttc cgttgctagc cagcactatg acttcttacc accaactatt
    33181 acggcctttt cagagcgcta tcctgactat aagaacttcc gtatttttga atcaactact
    33241 gttcaaatat tagatgaagt ggcgcaaggg catagtgaga ttgggattat ctacctcaac
    33301 aatcaaaata aaaaggggat tatgcaacgg gttgaaaagt taggtctgga ggtcatcgaa
    33361 ttgattcctt tccataccca tatttatctc tgtgagggtc atcctttagc ccagaaagag
    33421 gaattagtca tggaggattt agcggattta ccaacggttc gtttcactca agagaaagac
    33481 gagtaccttt attattcaga gaactttgtc gataccagcg ctagctcaca gatgtttaat
    33541 gtgacagacc gtgccacctt gaatggtatt ttggagcgga cggacgccta tgcgacaggt
    33601 tctggatttt tagatagtga cagtgttaat ggcattacag ttattcgtct caaggataac
    33661 ctagataacc gcatggtcta tgttaaacgt gaagaagtgg agcttagtca agctgggact
    33721 ctcttcgtag aagtcatgca agaatatttt gatcaaaaga ggaaatcatg aaaaaaagag
    33781 caatagtggc agtcattgta ctgcttttaa ttgggctgga tcagttggtc aaatcctata
    33841 tcgtccagca gattccactg ggtgaagtgc gctcctggat tcccaatttc gttagcttga
    33901 cctacctgca aaatcgaggt gcagcctttt ctatcttaca agatcagcag ctgttattcg
    33961 ctgtcattac tctggttgtc gtgataggtg ccatttggta tttacataaa cacatggagg
    34021 actcattctg gatggtcttg ggtttgactc taataatcgc gggtggtctt ggaaacttta
    34081 ttgacagggt cagtcagggc tttgttgtgg atatgttcca ccttgacttt atcaactttg
    34141 caattttcaa tgtggcagat agctatctga cggttggagt gattatttta ttgattgcaa
    34201 tgctaaaaga ggaaataaat ggaaattaaa attgaaactg gtggtctgcg tttggataag
    34261 gctttgtcag atttgtcaga attatcacgt agtctcgcga atgaacaaat taaatcaggc
    34321 caggtcttgg tcaatggtca agtcaagaaa gctaaataca cagtccaaga gggtgatgtc
    34381 gtcacttacc atgtgccaga accagaggta ttagagtatg tggctgagga tcttccgcta
    34441 gaaatagtct accaagatga ggatgtggct gtcgttaaca aacctcaggg aatggttgtg
    34501 cacccgagtg ctggtcatac cagtggaacc ctagtaaatg ccctcatgta tcatattaag
    34561 gacttgtcgg gtatcaatgg ggttctgcgt ccagggattg ttcaccgtat tgataaggat
    34621 acgtcaggtc ttctcatgat tgctaaaaac gatgatgcgc atctagtact tgcccaagaa
    34681 ctcaaagata aaaagtctct ccgcaaatat tgggcgattg ttcatggaaa tctgcctaat
    34741 gatcgtggtg taattgaagc gccgattggc cggagtgaaa aagaccgtaa gaaacaggct
    34801 gtaactgcta aagggaagcc tgcagtgacg cgttttcacg tcttggaacg ctttggcgat
    34861 tatagcttag tagagttgca actggagaca gggcgcactc atcaaatccg tgtccacatg
    34921 gcttatatcg gccatccagt cgctggtgat gaggtctatg gtcctcgcaa gactttgaaa
    34981 ggacatggac aatttcttca tgccaagact ttaggtttta ctcatccgag aacaggtaag
    35041 accttggaat ttaaagcaga tatcccagag atttttaagg aaaccttgga gagattgaga
    35101 aagtaagaat gaaaaagaaa ttaactagtt tagcacttgt aggcgctttt ttaggtttgt
    35161 catggtatgg gaatgttcag gctcaagaaa gttcaggaaa taaaatccac tttatcaatg
    35221 ttcaagaagg tggcagtgat gcgattattc ttgaaagcaa tggacatttt gccatggtgg
    35281 atacaggaga agattatgat ttcccagatg gaagtgattc tcgttatcca tggagagaag
    35341 gaattgaaac gtcttataag catgttctaa cagaccgtgt ctttcgtcgt ttgaaggaat
    35401 tgagtgtcca aaaacttgat tttattttgg tgacccatac ccacagtgat catattggaa
    35461 atgttgatga attactgtct acctatccag ttgaccgagt ctatcttaag aaatatagtg
    35521 atagtcgtat tactaattct gaacgtctat gggataatct gtatggctat gataaggttt
    35581 tacagactgc tgcagaaaaa ggtgtttcag ttattcaaaa tatcacacaa ggggatgctc
    35641 attttcagtt tggggacatg gatattcagc tctataatta tgaaaatgaa actgattcat
    35701 cgggtgaatt aaagaaaatt tgggatgaca attccaattc cttgattagc gtggtgaaag
    35761 tcaatggcaa gaaaatttac cttgggggcg atttagataa tgttcatgga gcagaagaca
    35821 agtatggtcc tctcattgga aaagttgatt tgatgaagtt taatcatcac catgatacca
    35881 acaaatcaaa taccaaggat ttcattaaaa atttgagtcc gagtttgatt gttcaaactt
    35941 cggatagtct accttggaaa aatggtgttg atagtgagta tgttaattgg ctcaaagaac
    36001 gaggaattga gagaatcaac gcagccagca aagactatga tgcaacagtt tttgatattc
    36061 gaaaagacgg ttttgtcaat atttcaacat cctacaagcc gattccaagt tttcaagctg
    36121 gttggcataa gagtgcatat gggaactggt ggtatcaagc gcctgattct acaggagagt
    36181 atgctgtcgg ttggaatgaa atcgaaggtg aatggtatta ctttaaccaa acgggtatct
    36241 tgttacagaa tcaatggaaa aaatggaaca atcattggtt ctatttgaca gactctggtg
    36301 cttctgctaa aaattggaag aaaattgatg gaatctggta ttattttaac aaagaaaatc
    36361 agatggaaat tggttgggtt caagataaag agcagtggta ttatttggat gttgatggtt
    36421 ctatgaagac aggatggctt caatatatgg ggcaatggta ttactttgct ccatcagggg
    36481 aaatgaaaat gggctgggta aaagataaag aaacctggta ctatatggat tctactggtg
    36541 tcatgaagac aggtgagata gaagttgctg gtcaacatta ttatctggaa gattcaggag
    36601 ctatgaagca aggctggcat aaaaaggcaa atgattggta tttctacaag acagacggtt
    36661 cacgagctgt gggttggatc aaggacaagg ataaatggta cttcttgaaa gaaaatggtc
    36721 aattacttgt gaacggtaag acaccagaag gttatactgt ggattcaagt ggtgcctggt
    36781 tagtggatgt ttcgatcgag aaatctgcta caattaaaac tacaagtcat tcagaaataa
    36841 aagaatccaa agaagtagtg aaaaaggatc ttgaaaataa agaaacgagt caacatgaaa
    36901 gtgttacaaa tttttcaact agtcaagatt tgacatcctc aacttcacaa agctctgaaa
    36961 cgagtgtaaa caaatcggaa tcagaacagt agtagaaaag aaggttttag ggccttcttt
    37021 ttcctatcaa ctcttttcta tttcctgtta ttcatgttat aatggataaa tatgaataat
    37081 cggagtgaga ctatgaaata caaacggatt gtctttaagg tgggtacttc ttctctgaca
    37141 aatgaggatg gaagtttatc acgtagtaag gtaaaggata ttacccagca gttggctatg
    37201 ctgcacgagg ctggtcatga gttgattttg gtgtcttcag gtgccattgc ggctggtttt
    37261 ggagccttag gatttaaaaa gcgtccgact aaaattgctg ataaacaggc ttcagcagcg
    37321 gtagggcagg gacttttgtt ggaagaatat acgaccaatc ttctcttgcg tcaaatcgtt
    37381 tctgcacaaa tcttgctgac ccaagatgac tttgtggata agcgtcgtta taaaaatgcc
    37441 catcaggctt tgtcggtttt gctcaaccgt ggggcaattc ctatcatcaa tgagaatgat
    37501 agtgtcgtta ttgatgagct caaggttggg gacaatgaca ctctaagtgc tcaagtagcg
    37561 gcgatggtac aagcagacct tttagttttc ttgacagatg tggacggtct ctatactgga
    37621 aatcctaatt cagatccaag agccaaacgc ttggagagaa tcgagaccat caatcgtgag
    37681 attattgata tggctggtgg agctggttcg tcaaacggaa ctgggggtat gttaaccaaa
    37741 atcaaggctg caactatcgc gacggaatca ggagttcctg tttatatctg ctcatccttg
    37801 aaatcagatt ccatgattga ggcggcagag gagaccgagg atggttctta ctttgttgct
    37861 caagagaagg ggcttcgtac ccagaaacaa tggcttgcct tctatgctca gagtcaaggt
    37921 tctatttggg ttgataaagg ggctgcggaa gctctctctc aacatggaaa gagtcttctc
    37981 ttatctggta tcgttgaagc agaaggagtc ttttcttacg gtgatatcgt gacagtattt
    38041 gataaggaaa gtggaaaatc acttggaaaa ggacgcgtgc aatttggagc atctgctttg
    38101 gaggatatat tgcgttctca aaaagccaag ggtgtcttga tttaccgtga cgactggatt
    38161 tccattactc ctgaaatcca actacttttt acagaatttt agaggtaaac tatggtgagt
    38221 agacaagaac aatttgaaca ggtacaggct gttaaaaaat cgattaacac agctagtgaa
    38281 gaagtgaaaa accaagcctt gctagccatg gctgatcact tagtggctgc tactgaggaa
    38341 attttagcgg ctaatgccct cgatatggca gcggctaagg ggaaaatctc agatgtgatg
    38401 ttggatcgtc tttatttgga tgcagatcgt atagaagcga tggcaagagg aattcgtgaa
    38461 gtggttgcct taccagatcc aatcggtgaa gttttagaaa caagtcagct tgaaaatggt
    38521 ttggttatca caaaaaaacg tgtagctatg ggtgtcatcg gtattatcta tgaaagccgt
    38581 ccaaatgtga cgtctgatgc ggctgctttg actcttaaga gtggaaatgc ggttgttctt
    38641 cgtagtggta aggatgccta tcaaacaacc catgccattg tcacagcctt gaagaagggc
    38701 ttggagacga ctactattca tccaaatgtg attcaactgg tggaggatac tagccgtgaa
    38761 agtagttatg ctatgatgaa ggccaagggc tatctagacc ttctcattcc tcgtggagga
    38821 gctggcttga tcaatgcagt agttgagaat gccattgtac ctgttatcga gacagggact
    38881 gggattgtcc atgtctatgt ggataaggat gcagacgaag acaaggcgct gtctatcatc
    38941 aacaatgcta aaaccagtcg tccttctgtt tgtaatgcca tggaggttct gctggttcat
    39001 gaaaacaagg cagcaagcat ccttcctcgc ttggatcaaa tgctggttgc agagcgtaag
    39061 gaagctggac tggaaccaat tcaattccgc ttggatagca aagcaagcca gtttgtttca
    39121 ggtcaagcag ctgagaccca agactttgac accgagtttt tagactatgt ccttgctgtt
    39181 aaggttgtga gcagtttaga agaagcggtt gcgcacattg aatcccacag cacccatcat
    39241 tcggatgcta ttgtgacgga aaatgctgaa gctgcagcat actttacaga tcaagtggac
    39301 tctgcagcgg tgtatgttaa tgcctcaact cgtttcacag atggaggaca atttggtctt
    39361 ggttgtgaaa tggggatttc tactcagaaa ttgcacgcgc gtggtccaat gggcttgaaa
    39421 gagttgacca gctacaagta tgtggttgct ggtgatgggc agataaggga gtaagagatg
    39481 aagattggat ttatcggttt ggggaatatg ggtgctagct tggcaaaatc tgtcttgcag
    39541 actaggacgt cagatgagat tctccttgcc aatcgtagtc aagctaaggt agatgctttc
    39601 attgcagact ttggtggtca ggcttccagc aatgaagaaa tgtttgcaga agcagatgtg
    39661 atttttctag gagttaagcc tgctcagttt tctgaactgc tttctcaata ccagaccatc
    39721 cttgaaaaaa gagaaagtct tcttttgatt tcgatggcag ctggattgac cttagaaaaa
    39781 ctagcaagtc ttatcccaag tcaacaccga attattcgta tgatgcctaa tacctctgct
    39841 tctatcgggc aaggagtgat tagttatgcc ttgtctccta attgcagggc tgaggacagt
    39901 gagctctttt gtcagctttt atccaaggct ggtctcttgg ttgaattagg agaaagctta
    39961 atcaatgcag cgacaggtct tgcaggctgt ggaccagcct ttgtctatct ctttattgag
    40021 gctttggcag atgcaggtgt tcagacggga ttaccacgag aaacagcctt gaaaatggca
    40081 gcccaaactg tggtaggagc tgggcaattg gtcctagaaa gccagcaaca tcctggagtt
    40141 ttgaaagatc aagtttgtag tccaggcggt tcgactattg ctggcgtagc aagcttagaa
    40201 gcgcatgctt ttcgaggcat agtcatggag gcagttcatc aagcctataa acgaacacaa
    40261 gaactaggta aataagaggt agctttgact gcctctttta tggtggctga aatgagaaga
    40321 cacaaaaaga ttgtcacaaa ctcctatttt tttgatagaa tagaagtagt aaaaaagaaa
    40381 tgagttagac atgtcaaaag gatttttagt ctctcttgag ggaccagagg gagcaggcaa
    40441 gaccagtgtt ttagaggctc tgctaccaat tttagaggaa aaaggagtag aggtgctgac
    40501 gacccgtgaa cctggcggag tcttgattgg ggagaagatt cgggaagtga ttttggatcc
    40561 aagtcatact cagatggatg cgaagacaga gcttttgctc tatattgcca gtcgcagaca
    40621 gcatttggtg gaaaaagttc ttccagccct tgaagctggc aagttggtca tcatggatcg
    40681 ttttatcgat agttctgttg cctatcaggg atttggtcgt ggcttagata ttgaagccat
    40741 tgactggctc aatcagtttg cgacagatgg cctcaaaccc gatttgacac tctattttga
    40801 catcgaggtg gaagaagggc tggctcgtat tgctgctaat agtgaccgcg aggttaatcg
    40861 tttggatttg gaagggttgg acttgcataa aaaagttcgt caaggctacc tttctcttct
    40921 ggataaagag ggaaatcgca ttgtcaagat tgatgctagt ctccctttgg agcaagttgt
    40981 ggaaactacc aaggctgtct tgtttgacgg aatgggcttg gccaaatgaa acaagatcaa
    41041 ctaaaggctt ggcaaccagc tcagtttgac cgttttgtcc gtatcttaga acaagaccag
    41101 ctcaatcacg cctatctctt ttcaggtttc tttggaagct tggaaatggc gcaattttta
    41161 gctaagagcc ttttttgtac ggataaagtt ggcgtcttac catgtgagaa atgccgaagt
    41221 tgcaagctga ttgaacagga agagtttcca gatgtcacct tgattaagcc agtcaatcag
    41281 gtcatcaaga cagaacgcat tcgggaattg gtgggacagt tttctcaagc agggattgaa
    41341 agccagcaac aggtctttat catcgagcaa gcggataaaa tgcatcccaa cgcagccaat
    41401 tctctgctca aggtcatcga agaaccccag agtgaagttt atattttctt cttgactagc
    41461 gatgaggaaa agatgttacc gacaatccga agtcggactc agatcttcca ctttaaaaag
    41521 caagaagaaa aacttatctt actcttagaa caaatgggac ttgttaagaa aaaagcgact
    41581 cttttagcta agtttagtca atcgcgagct gaagcagaaa agttggcaca tcaggcaagt
    41641 ttttggacct tggtcgatga aagtgaacgc ctgctgactt ggttagtagc taagaaaaaa
    41701 gaaagttatc tacaggttgc caaattagcc aacttggcag atgataagga aaaacaggat
    41761 caggttttac ggattcttga agttctctgt gggcaggacc tcttgcaggt aagagtaaga
    41821 gtgattctac aagatttact agaagctaga aaaatgtggc aagctaatgt cagctttcaa
    41881 aatgccatgg aatatctggt cttgaaagaa atataaactc aaaaatgaat gataaagaaa
    41941 ggaaagggct gttttatgga caaaaaagaa ttatttgacg cgctggatga tttttcccaa
    42001 cagttattgg taaccttggc cgatgtggaa gccatcaaga aaaatctcaa gagcctggta
    42061 gaggaaaata cagctcttcg tttggaaaat tctaagttgc gagaacgctt gggtgaggtg
    42121 gaagcagatg ctcctgtcaa ggccaagcat gttcgtgaaa gtgtccgtcg catttaccgt
    42181 gatggatttc acgtatgtaa tgatttttat ggacaacgtc gagagcagga cgaggaatgt
    42241 atgttttgtg acgagttgct atacagggag taggcatgca gattcaaaaa agttttaagg
    42301 ggcagtctcc ctatggcaag ctgtatctag tggcaacgcc gattggcaat ctagatgata
    42361 tgacctttcg agctatccag accttgaaag aagtagattg gattgctgct gaggatacgc
    42421 gcaatacagg tcttttgctc aagcattttg acatttccac caagcagatc agttttcatg
    42481 agcacaatgc caaggaaaaa attcctgatt tgattggttt cttgaaagca gggcaaagta
    42541 ttgctcaggt ctctgatgcc ggtttgccta gcatttcaga ccctggtcat gatttagtta
    42601 aggcagctat tgaggaagaa attgcagttg tgacagttcc aggtgcctct gcaggaattt
    42661 ctgccttgat tgccagtggt ttagcgccac agccacatat cttttacggt tttttaccga
    42721 gaaaatcagg tcagcagaag caattttttg gcttgaaaaa agattatcct gaaacacaga
    42781 ttttttatga atcacctcat cgtgtagcag acacgttgga aaatatgtta gaagtctacg
    42841 gtgaccgctc cgttgtcttg gtcagggaat tgaccaaaat ctatgaagaa taccaacgag
    42901 gtactatctc tgagttatta gaaagcattg ctgaaacgcc actcaagggc gaatgtcttc
    42961 tcattgttga gggtgccagt cagggtgtgg aggaaaagga cgaggaagac ttgttcgtag
    43021 aaattcaaac ccgcatccag caaggtgtga agaaaaacca agctatcaag gaagtcgcta
    43081 agatttacca gtggaataaa agtcagctct acgctgccta ccacgactgg gaagaaaaac
    43141 aataaaggga gacaggatgt aataattctg tctgtttctg tttaacttaa ttagtgatga
    43201 taatataaag atgtatcact tggtatagaa gctttggtat taagtttttt attaagccca
    43261 tacggaatac cgatggttgg agcagcagtt atagcgttct tagaaggtat aaatagaaaa
    43321 ataaggtcat tttaaatcaa aggattgata aatcagaaag aaggtgattt tttgcgaaca
    43381 tacgaaaata aagaagaact aaaagctgag atagagaaaa catttgagaa atatatttta
    43441 gaatttgata atattccaga aaatttaaaa gataagagag ctgatgaagt tgacagaact
    43501 ccagcagaaa accttgctta tcaggttggt tggaccaact tggttcttaa atgggaagaa
    43561 gatgaaagaa aggggcttca agtaaaaaca ccatcggata aatttaaatg gaatcaactt
    43621 ggtgaattat atcagtggtt cacagatacc tacgctcatt tatctctgca agagttgaaa
    43681 gcaaaattaa atgaaaatat taattctatc tctgcaatga ttgattcgtt gagtgaggaa
    43741 gaattatttg aaccgcatat gagaaagtgg gctgatgaag cgactaaaac agcgacttgg
    43801 gaagtgtata agtttattca tgtaaatacg gttgcacctt ttggaacttt cagaactaaa
    43861 atcagaaaat ggaagaagat agtattataa attatatttt taactttaaa aaatttcata
    43921 aaaatggtta ccaaaggcga tagaagaaaa actatcgtct ttttctttgc aaatttttaa
    43981 gaagggaggt gatcttgcat ggactttgaa tatttttata acagagaagc ggaaagattt
    44041 aacttcttaa aagtaccgga gatattagtt gatagagaag aatttcgggg cttatcagca
    44101 gaagcaatta tcctttattc catacttctt aaacagacag gaatgtcatt taagaata
//
LOCUS       DAVLZS010000014        43648 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLZS010000014 DAVLZS010000000
VERSION     DAVLZS010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43648
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.014"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            442..1803
                     /gene="trpE"
                     /locus_tag="VYO88_000777"
     CDS             442..1803
                     /gene="trpE"
                     /locus_tag="VYO88_000777"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1718914.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKSHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYLYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGAMDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKSTLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            1800..2366
                     /locus_tag="VYO88_000778"
     CDS             1800..2366
                     /locus_tag="VYO88_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1718915.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            2377..3381
                     /gene="trpD"
                     /locus_tag="VYO88_000779"
     CDS             2377..3381
                     /gene="trpD"
                     /locus_tag="VYO88_000779"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1718916.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            3378..4145
                     /gene="trpC"
                     /locus_tag="VYO88_000780"
     CDS             3378..4145
                     /gene="trpC"
                     /locus_tag="VYO88_000780"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1718917.1"
                     /translation="MSQEFLARILEQKVREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            4132..4731
                     /locus_tag="VYO88_000781"
     CDS             4132..4731
                     /locus_tag="VYO88_000781"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1718918.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRAELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            4709..5932
                     /gene="trpB"
                     /locus_tag="VYO88_000782"
     CDS             4709..5932
                     /gene="trpB"
                     /locus_tag="VYO88_000782"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1718919.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAYA"
     gene            5925..6701
                     /locus_tag="VYO88_000783"
     CDS             5925..6701
                     /locus_tag="VYO88_000783"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1718920.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(6673..7332)
                     /locus_tag="VYO88_000784"
     CDS             complement(6673..7332)
                     /locus_tag="VYO88_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1718921.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLKKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            7402..7848
                     /locus_tag="VYO88_000785"
                     /pseudo
     CDS             7402..7848
                     /locus_tag="VYO88_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(8076..9254)
                     /locus_tag="VYO88_000786"
     CDS             complement(8076..9254)
                     /locus_tag="VYO88_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1718922.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDSNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            9534..10796
                     /locus_tag="VYO88_000787"
     CDS             9534..10796
                     /locus_tag="VYO88_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1718923.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            10799..11695
                     /locus_tag="VYO88_000788"
     CDS             10799..11695
                     /locus_tag="VYO88_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV1718924.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            11710..12027
                     /locus_tag="VYO88_000789"
     CDS             11710..12027
                     /locus_tag="VYO88_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1718925.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPITDYGMMNGSKVLDLAES
                     LLD"
     gene            12044..12361
                     /locus_tag="VYO88_000790"
     CDS             12044..12361
                     /locus_tag="VYO88_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1718926.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            12371..13726
                     /locus_tag="VYO88_000791"
     CDS             12371..13726
                     /locus_tag="VYO88_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1718927.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            14050..15525
                     /locus_tag="VYO88_000792"
     CDS             14050..15525
                     /locus_tag="VYO88_000792"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV1718928.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVNFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            15522..16370
                     /locus_tag="VYO88_000793"
     CDS             15522..16370
                     /locus_tag="VYO88_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV1718929.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEDPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTGLDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            16385..17155
                     /locus_tag="VYO88_000794"
     CDS             16385..17155
                     /locus_tag="VYO88_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV1718930.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            17919..18197
                     /locus_tag="VYO88_000795"
                     /pseudo
     CDS             17919..18197
                     /locus_tag="VYO88_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18307..18510)
                     /locus_tag="VYO88_000796"
     CDS             complement(18307..18510)
                     /locus_tag="VYO88_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1718931.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(18541..19149)
                     /locus_tag="VYO88_000797"
     CDS             complement(18541..19149)
                     /locus_tag="VYO88_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1718932.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(19188..19358)
                     /locus_tag="VYO88_000798"
     CDS             complement(19188..19358)
                     /locus_tag="VYO88_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1718933.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(19370..19936)
                     /gene="amaP"
                     /locus_tag="VYO88_000799"
     CDS             complement(19370..19936)
                     /gene="amaP"
                     /locus_tag="VYO88_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1718934.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(20020..20184)
                     /locus_tag="VYO88_000800"
     CDS             complement(20020..20184)
                     /locus_tag="VYO88_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1718935.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPAIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            20627..22108
                     /locus_tag="VYO88_000801"
     CDS             20627..22108
                     /locus_tag="VYO88_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1718936.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            22471..23472
                     /locus_tag="VYO88_000802"
     CDS             22471..23472
                     /locus_tag="VYO88_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1718937.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            23621..24538
                     /locus_tag="VYO88_000803"
     CDS             23621..24538
                     /locus_tag="VYO88_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1718938.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            24549..25439
                     /locus_tag="VYO88_000804"
     CDS             24549..25439
                     /locus_tag="VYO88_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1718939.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFKPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            25468..27063
                     /locus_tag="VYO88_000805"
     CDS             25468..27063
                     /locus_tag="VYO88_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1718940.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYD"
     gene            27094..28413
                     /locus_tag="VYO88_000806"
     CDS             27094..28413
                     /locus_tag="VYO88_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1718941.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(28623..28695)
                     /locus_tag="VYO88_000807"
     tRNA            complement(28623..28695)
                     /locus_tag="VYO88_000807"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28660..28662),aa:Lys,seq:ctt)
     gene            complement(28960..30231)
                     /locus_tag="VYO88_000808"
     CDS             complement(28960..30231)
                     /locus_tag="VYO88_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1718942.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     ISLSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            30501..30740
                     /locus_tag="VYO88_000809"
     CDS             30501..30740
                     /locus_tag="VYO88_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718943.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            30895..31083
                     /locus_tag="VYO88_000810"
     CDS             30895..31083
                     /locus_tag="VYO88_000810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718944.1"
                     /translation="MTWFEEIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFT
                     IDYTDDELLDKEAVFTTH"
     gene            31220..31399
                     /locus_tag="VYO88_000811"
     CDS             31220..31399
                     /locus_tag="VYO88_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1718945.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITIPHGE
                     LNKYTERGIRKQAGL"
     gene            31436..31888
                     /locus_tag="VYO88_000812"
     CDS             31436..31888
                     /locus_tag="VYO88_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1718946.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            32179..32649
                     /locus_tag="VYO88_000813"
     CDS             32179..32649
                     /locus_tag="VYO88_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1718947.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKIGLEEGEFYPYPKY"
     gene            32668..33756
                     /locus_tag="VYO88_000814"
     CDS             32668..33756
                     /locus_tag="VYO88_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1718948.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVVFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAILFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            33737..33895
                     /locus_tag="VYO88_000815"
     CDS             33737..33895
                     /locus_tag="VYO88_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEV1718949.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     KSVRENLI"
     gene            34005..35039
                     /locus_tag="VYO88_000816"
     CDS             34005..35039
                     /locus_tag="VYO88_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1718950.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            35041..37284
                     /locus_tag="VYO88_000817"
     CDS             35041..37284
                     /locus_tag="VYO88_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008288790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEV1718951.1"
                     /translation="MNTLLTLRGKSFTPKSAKGRGPITIPADSIVTLNHLNELYTSLE
                     RVKEYWSNNTIIDGVLISVYYNRVLAKSNRIDGFFNVGGGNAIPNETIVGAKFSNDKS
                     RHIITHYISKEVLDKTIEHTKKVITIFKDYFASAPMTSMVFSDSSKFNQIDYSKYGLS
                     KSKFKQYLRDACFVKGFGIEQADMSTIRNSIVTIYDVKTNLLTLLKQLDIDVSEANIM
                     DQTTVLLDEKNIELLLLKAPYLVSMIVEDFSSLSPENFYNDGNTFYNNLPFPTNEPII
                     GVIDTLFDDGVYFNEWVEYHDLISPDISKGSQDYKHGTAVSSVIVDGASLNPKLDDGC
                     GRFRVRHFGISLQSGFNSFTIIKQIREIVSQNPDIKVWNLSLGSNDEIRENFISVEGS
                     LLDEIQFDNDVIFIIAGTNGIAPDGQRKKIGAPADSLNSIIVNSVDFSNQVVSYSREG
                     VVLSFFIKPDVSYYGGGNGDFINVCEPLGLARVAGTSFAAPFIARKMAYLIHIMGLSR
                     EEAKALLIDSAIPWNDKKTFADISLLGYGVVPIKIEDILSTPDDEIKFIVSDVSRAYE
                     TYNYDFPVPISKEHYPYVAKATMCYFPKCSRNQGVDYTNTEMQLSLGVLDKKGIKTIN
                     NDNQYSENAPGYVREKSARNIFRKWDNVKHLGEKFSSRKKAKPILNPSNPQWGMSVKT
                     IERLRNDDGYGIRFGVVVTLKELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSL
                     NEEIEFE"
     gene            37335..38354
                     /locus_tag="VYO88_000818"
     CDS             37335..38354
                     /locus_tag="VYO88_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1718952.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYKDFYEFQNRTYISRKENEEEYSN
                     LIYESLFSDTVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDRYIWSQIAERSISGS
                     VPVIIYHYVPHFDPGNPIRAKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            38367..39317
                     /locus_tag="VYO88_000819"
     CDS             38367..39317
                     /locus_tag="VYO88_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1718953.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPETVDVAAVEADLQDRLAELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLDAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            39319..40062
                     /locus_tag="VYO88_000820"
     CDS             39319..40062
                     /locus_tag="VYO88_000820"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1718954.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            40073..41869
                     /gene="pepF"
                     /locus_tag="VYO88_000821"
     CDS             40073..41869
                     /gene="pepF"
                     /locus_tag="VYO88_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1718955.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            42116..42670
                     /locus_tag="VYO88_000822"
     CDS             42116..42670
                     /locus_tag="VYO88_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV1718956.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTGFSSQYGWVHSFAHGADLLTEVVCHPDFPINRIHEVFDILGQLFKRMS
                     ILFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDDLKEAIQSFQY"
     gene            42781..43449
                     /locus_tag="VYO88_000823"
     CDS             42781..43449
                     /locus_tag="VYO88_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV1718957.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFANKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLTIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(43474..>43648)
                     /locus_tag="VYO88_000824"
     CDS             complement(43474..>43648)
                     /locus_tag="VYO88_000824"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718958.1"
                     /translation="KHCFEVADRTDEVSLKHCFEVVDETDEVSNHTYGKVKLTWFEEI
                     FEEYHTKKPCSSR"
BASE COUNT        13512 a         7366 c         9317 g        13453 t
ORIGIN      
        1 tacctacggc aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt ataaaggtgt
       61 accgagatga acatctcttc atcaatgtct ctggtcgtgg aggcaaggac ctagctgcga
      121 ttgcagatta ctagaagcta aaaaataata gatggaaaaa ttacagttct ttctctcaca
      181 gagagcttgt ggttgctgaa aacaagcaga gaaagctgta aagttgggtt catctgaaac
      241 gagagaagaa aacatcattc tcaagggagt gccctttatc gcacagcctg ttacaggaga
      301 tatctgagac aggaatgaga gataggagaa atcctataat tgaggtggca ccgcgaattt
      361 cgtcctcacg caagttattt tgcgtgggga tttttcatat agtcaccacg gactagaagt
      421 agaactgaaa gggaaattac aatggaacga atcattcatg gagatgtctt atcaccaatc
      481 ttggcttata tgcgcttaaa ggggcaacac aaggttatct tagagagtat tccgagagac
      541 aaggaaacag ctcgtttttc tatcttagcc tataatcctg tttttgagat taagtttgaa
      601 aatggagttc tttatcaaaa tggtcaagtg attgatcggg atcccttgga tttcctttat
      661 gaagtgattc ataagagtca gcaccactca gagctacctt ttggtggtgg agccattggt
      721 tttgtgggtt acgatatgat ttcgctttat gaagaaattg gtcaaatccc tgaggataca
      781 attgggacgc cagacatgca tttctttgtc tatgagagct atatggtctt tgaccacaag
      841 aaggagaaga tacatgtcat agaggatgca ctttatagtg agcgcagtca agaagccttg
      901 gaaaaatcct tgaaccaagt gcttgaggaa ttacgcattc ctgctccaaa tgaatttgaa
      961 gacttggatc tatctccgtt agacttcaaa tcccatatcg ctcctcagaa gtttgaggaa
     1021 atggtggaaa ccgctcgcga cttgattcgt aatggcgata tgttccaatg tgtactcagt
     1081 cagcgcttct cagcagaagt tactggaaat ccatttgact tctacagaaa tctccgcgtg
     1141 accaatccat ccaattacct ctatttatat gactttgggg attatcaaat catcggtgcc
     1201 agtccagaaa gtttggtttc tgtcaaaaat ggcatcgtga caaccaatcc gattgcaggg
     1261 acgcgaccaa gaggggctat ggatgaagaa gacaaggcct tggcgactga cctcctctct
     1321 gatgagaagg aaacagcaga acatcgaatg ttggtagact tggggcgtaa cgatattggc
     1381 cgcatctctg aaacggccag tgtccaagtc actaagtata tggaagtgga gctcttccgt
     1441 tatgttatgc atctgaccag cgtggtcaag gggcgtttgc ttccagaact cactgctatg
     1501 gatgccttga aatcaacgct tccagctgga accgtttctg gagcaccaaa aattcgagct
     1561 atgagacgca tctatgaact ggaaacggaa aaacggggcg tatatgcagg agcaatcggc
     1621 tacttgtctg cgacgggtga tatggatttg gccattgcca tccgaaccat gattctcaaa
     1681 aatcaaagag cctatgtgca ggctggggca gggattgtct acgactctat cgcccaaaac
     1741 gaataccaag aaaccattaa caaagcaaaa tctatgacta gaattggaga actaagacca
     1801 tgattttatt gattgacaac tatgattctt ttacctataa cttggcccaa tacattggga
     1861 attttgcaga agttcaggtt ttgagaaatg atgattccaa gctgtatgaa gaagctgaaa
     1921 aagcagatgg tctggtcttt tctcctggtc ctggttggcc agttgatgct ggaaagatgg
     1981 aagacatgat tcgtgatttt gcaggcaaga agccgattct agggatttgt ttgggccacc
     2041 aagccattgc agaagtcttt ggtggtaagc taggtttggc tccaaaagtc atgcatggga
     2101 aacagagcaa tatcaacttt gaagcgccat ctgttttgta tcaaggtatt gaggatggcc
     2161 gtgcggtcat gcgttatcac agtattttga ttgaggaaat gccagaagac tttgaagtga
     2221 cagctcgttc gactgatgac caagccatca tggggattca acataaaaac ctaccgattt
     2281 atggcttcca gtaccatcca gagagcattg gaacgccaga cggcttgtct tctattcgga
     2341 attttatcga gaaggttgta aagtgaggaa actaggatga aagagattat tgaaaaacta
     2401 gcaaaatttg aaaatttatc aggtgtggaa atgacggatg tcattgagcg tatcgtaact
     2461 gggcgtgtaa ctgaagcgca gattgcttct ctcctcttag ctcttaagat gaagggggaa
     2521 acacctgaag aacgcacagc cattgcccaa gtcatgagag gacatgccca gcatattcca
     2581 actgagattc atgatgctat ggacaactgt ggtacaggtg gggacaagtc tttcagtttt
     2641 aatatttcca caactgcagc ctttgtcttg gctggtggcg gtattcacat ggccaagcat
     2701 ggtaaccgct cgatttcttc taaatctggt tccgcagatg tcctcgaagc cttgggaatc
     2761 aatcttgacc tcaaaccagc tgaactaggt aaggtctttg ataaaactgg aatcgtcttt
     2821 ctcttcgcta aaaatatgca cccagctatg aaatacatca tgccagctcg tttggaattg
     2881 ggaattccaa cgattatgaa cttgactggt ccactgattc atccaatggc tttagaaaca
     2941 cagcttcttg gaattagtcg tccagaactc ctagaaagta cagctcaggt tttgaaaaat
     3001 atgggtcgca aacgtgccat cgtggttgct ggaccagaag ggttggatga agctggcttg
     3061 aacggaacaa ccaagattgc acttcttgaa aatggcgaaa tcagcttgtc aagctttact
     3121 ccagaggatt tgggaatgga aggctatgct atggaagata ttcgtggtgg gaatgctcag
     3181 gaaaatgcag aaattttgct tagcgttctg aaaaacgaag caagtccatt cttggaaacg
     3241 acagtcttga atgctggtct tggtttctat gctaatggta agattgatag catcaaggaa
     3301 ggagttgcct tggcccgtca agtgattgct agaggcaagg cccttgaaaa actcagactg
     3361 ttacaggagt accaaaaatg agtcaggaat ttttagcacg aatcttagag cagaaggtgc
     3421 gtgaggtgga gcagatgaag ctggagcaaa tccagcctct gcgccagacc tatcgcttgg
     3481 cagaattttt gaagaatcat caggaccgct tgcaggtaat cgctgaggtc aagaaagcta
     3541 gccctagttt gggagatatc aatctcgatg tggatattgt gcaacaggcc cagacttatg
     3601 aagaaaacgg agcagtgatg atttcggtgt tgacagatga ggttttcttt aaagggcatt
     3661 tggattatct acgggaaatt tccagtcagg tagagattcc gacgctcaac aaagacttta
     3721 tcatcgatga aaagcaaatc atccgcgctc gcaatgcagg tgcgacagtt atcttgctca
     3781 ttgtggcagc cttgtccgaa gaacgcctca aggaactgta tgactacgcg acagagcttg
     3841 gtctggaagt cttagtggag actcacaatc tagctgaact agaggtagcc cacagacttg
     3901 gtgctgagat tatcggggtc aacaaccgca acttgactac ctttgaggtc gacttgcaga
     3961 ccagtgtaga tttagcccct tactttgagg aaggtcgcta ttacatttct gaatctgcca
     4021 ttttcacagg gcaggatgcg gaacgactag ccccatactt taacggaatt ttggtaggga
     4081 cagctcttat gcaggcagaa aatgtggccc agagaatcaa ggagttgcag attgacaaag
     4141 gttaaaattt gtggactatc gaccaaagaa gcggtggaaa cagccgtttc agcaggagcc
     4201 gactatatcg gttttgtctt tgcacctagt aaaagacagg tgactttaga agaggcagct
     4261 gagttggcaa agcttattcc tgcagatgtc aaaaaggttg gtgtatttgt ttcaccaagt
     4321 cgggcagaac tgctggaagc gattgacaaa gttggcttgg acttggttca agttcacggt
     4381 caggtggcag atgatttatt tgagaatttg ccttgtgcta gcattcaggc tgtgcaggta
     4441 gatggagagg gtcatgtgcc caattctcag gcagactatc tactctttga tgcccctgtg
     4501 gctgggagtg gccagccctt tgattggggt caactggata cgactggact agcacagccc
     4561 ttctttatcg caggtggcct taatgaagat aatgtagtaa aagcaattca acactttact
     4621 ccctatgcag tagatgtatc aagcggagtg gagacagatg gacaaaaaga tcatgaaaag
     4681 attagaagat ttatagagag ggtaaagaat ggcatatcaa gaaccaaata aagatggatt
     4741 ttacggaaaa tttggcggac gttttgtccc agaaacattg atgacagcag ttttggagtt
     4801 ggagaaggcc taccgtgaaa gtcaggcaga cccaagtttc caagaggaat taaaccagct
     4861 tttgcgccag tatgtgggac gtgaaactcc cctttactac gcaaaaaact tgacccagca
     4921 tatcggcgga gccaagattt atctcaaacg ggaagacctt aaccatacag gagcccacaa
     4981 gattaacaat gccttaggac aagtttggct tgccaaacgc atgggtaaaa agaaaattat
     5041 cgcagaaact ggtgctggtc agcacggtgt ggcaactgca actgctgcgg ccctctttaa
     5101 catggaatgt accatctaca tgggtgagga agatgtcaaa cgccaagccc tcaatgtctt
     5161 ccgtatggag cttttgggag ctaaggtcga ggccgtgaca gatggttcgc gcgtgctcaa
     5221 ggatgcggtc aatgcagccc ttcgttcatg ggtggctaat atcgacgata cccactatat
     5281 ccttggttct gccttggggc ctcatccatt tccagaaatc gttcgtgact tccaaagtgt
     5341 catcggtcga gaggctaaac aacagtaccg tgacttgaca ggtcgagatc tgccagatgc
     5401 cctagtagcc tgtgttggtg gtgggtcgaa tgccatcggt ctcttccatc cctttgtaga
     5461 agatgagtca gtagccatgt atggagctga agcggctgga tttggtgtgg atacggagca
     5521 ccacgcagct accttgacca agggtcgtcc aggtgtcctt cacggttccc tcatggatgt
     5581 gctccaagat gcccatggtc aaattcttga agccttctct atctcagcag gtttggacta
     5641 tcctggtatc ggtccagagc attctcacta ccacgatatt aaacgtgcca gctatgtccc
     5701 tgtgacagac gaagaagcct tggaaggatt ccaactcttg tctcgtgtgg aagggattat
     5761 cccagctttg gaatctagcc atgctatcgc ctttgcggtg aaattggcca aagaacttgg
     5821 accagaaaag tctatgattg tatgcctatc aggtcgtggg gacaaggatg tggttcaagt
     5881 aaaagaccgc ttggaagcag atgcagcaaa gaagggagaa gcttatgcct aagacactaa
     5941 caaaaaaatt aaatgctatt aaagcagctg gaaaaggaat ttttgttccc tatatcatgg
     6001 ctggtgacca cgaaaaaggt ttggatggtc ttgctgaaac aattcacttt ttagaagatt
     6061 tgggtgtctc tgcaattgaa gtgggtattc ccttttcaga ccctgttgca gatggacctg
     6121 ttatcgaaga agctggcttg cgcagtttag cccacgggac ctctacccag gctttagttg
     6181 aaaccttgaa aaccattgaa acagagattc cactggtcat catgacctac ttcaaccccc
     6241 tctttcagta cggtgtggag aactttgtca aagatctggc tgatacagct gtgaagggct
     6301 tgattatccc agacctgcct catgaacatg ccaactttgt agaaccattt ttggcagata
     6361 cagatatcgc cttgattcct ttagtaagct tgaccacagg aattgagcgc cagaaagagt
     6421 tgattgaagg ggcggaggga ttcgtctatg ccgttgccat caatggggta acagggaaat
     6481 caggcaatta ccgtgcagat ttggacaagc acttggcgca acttcatcaa gtggccgaca
     6541 tcccagtctt gacaggtttt ggtgtatcta gtcaagccga tctggaacgc ttcaatgcgg
     6601 tgtcagatgg tgttatcgtc ggttcgaaaa tagtaaaagc tctccaccaa ggagagccga
     6661 ttcaggactt tatcaaacaa gcagtagctt accaaaaata attaaacaag tagcaagtaa
     6721 gaggaaaggc acgaaaggaa gtctttcctt tttctttttc aggagaaagg ccaggatacc
     6781 cgtcgcagaa gcaaactgaa tcaagatcag taactccgtt acgctaaaga cgagagcaca
     6841 agaagctaaa aagaggaaat ctcctgcgcc catgcggata tcgataaaat gagccaaaat
     6901 tccaagagca aggaaggaga ccatgaccag attccagcca gaggaagcta ttaggattag
     6961 gtggaaagtc atccagacca gtaagggata ttcctgatgg tgaaagtcgt agatacccaa
     7021 ggtcaaacca gcggtgatta ggacgacttg ccccaaggaa agcaattccc aagagtaaag
     7081 cagaaagagg agtcctaagc ctagttcaaa gagggcatac cagacaggat agcgaacttt
     7141 gcagtagcga cagcgaaagc gattgaagac ctgtgagaga atcggaatca aatctaaggg
     7201 acgcaagcga gtctgacagg aatcgcagtg actggctgaa ctgataatgg attgctctgg
     7261 aaaacggtca atgaccaaac caagaaagga agcgagaatg ctcccgacga gaaaaaaata
     7321 aaaatcaatc atacttatct attcgtaaaa aatgggagaa atagtataat ggagaaacat
     7381 agataagatg gtgaggaaaa gatgacaatt cgttttgaag aaaaggtgag tatagaaaac
     7441 gctcaatttg tatgccaatg gtccaactcc ctaggcaaat cctttcaaga acaatggatg
     7501 ggaccaagga ttccttttct actgaccctt caagccttgg aagaagtatt ttcaatcttt
     7561 gatgaacaag agtttgtggg ccttatccag aaaatcaggc tagaagacag caatcttcat
     7621 atcgggagat tttttatcaa cccctagaaa caggggcaag gcttaggtag ccagacttta
     7681 aggaaatttg ttagtttggc ctttgaaaat gaagatatag ataatatttc tctaaatgtc
     7741 ttcgaggcaa atcaaagagc tcagaatctt taccaaaaag aaggatttga aatcgttcaa
     7801 atggttgaag cacctgtacg aaaatatagt ggattgaaac tagaatagta cacctctact
     7861 tctaaaacat tgttagaaat cgatttgact gtcccgatcg attcgtcctg ttattatttc
     7921 attttactat acattatgaa aaatgggaga taggagtata attccaaata taaagaaagc
     7981 gaacaaaaca gaattctgat tttcagaaaa caggtttatt cgctttttat gatatactcc
     8041 ctctttttag cctatttatt aaatgtaata gaaaattaag aatgtagaat tgtatgatac
     8101 aaacaaagtg caatagctga gtgtgcggct gtaaaatcat tgtaaggttc aataatgact
     8161 tcaggtaggc gattatagag cagtttgggt ttgtagttca tttcactata tagtttttgg
     8221 atgatgtgtt gatttgttag taaaggacta tgtaggtaga ttttttgaga gtcaatcatc
     8281 atactgatat ttaaaatggt ttgactaaga tagagtaagg cttgatggat aagtgtgatt
     8341 attccagtgt cacctaattg ataagcggtt aaaataactt ggatatcaat atcatcggca
     8401 tttttgacta aactaggaag tagagaatag ggagattgat gatatagaat ttttgatttt
     8461 ttgattaacc aagattctcc agcaaaagtt tgtaagcatc ccttgcgccc gcagctacat
     8521 tcttctccct cagatgaaac aactgtatgc cctatttctc caatcattag atttcctttc
     8581 ccataaatgt ttccgtcgta gatataagaa cagtgcatac ctctagcaaa atgaaaataa
     8641 gcaaaattag agtcattctg ttggcgacta aataggcgtt tacctatagc catacagtta
     8701 acattgttag agaaaaacaa aggcttatca aagtgggatt gaatcatttc taagtcgata
     8761 tgttgccata aaggattgtt tgttgttatt ttataatcat ctaaatagcg accaggtagc
     8821 gcgattccaa ttgcttctat ttcataatca gagcagttat ttaagaattg ctttagtgtc
     8881 tggttaatga gttgatttcc cttttcttgg attaactgtt tagtaacaat ttctttctct
     8941 tcctttaaga tatttcctag attatctcct aaagcaaaag tgaaatgttt ttcagatagt
     9001 tcacaaccaa tgtagtaaaa tcgtttagct tgaatgtcta gcaggatttt ttttctccct
     9061 acgcttgtat cgtgttcgtc ttcaccaagt tctaagagaa tattttcttt aatcagatca
     9121 tttgtgatac tgctagttgt tgcaggtgtt attcctgttt tagtagcgat ttcaattcgt
     9181 gaaatgggac ctaatgtgta aactgtttcc agtattttag ctcttagttg taattgtttc
     9241 ttagataagg tcatattagt tttcttccta gttgtcagat tcttaaaatc ctatgatttt
     9301 ttgctatgga taaatgtaga tgttaatctt tttaagcttt tcattactta ctggtctctt
     9361 tttattatat attgataata aaaaataatc aaatgtttac acaaatcctt gacaaggctt
     9421 tcttatagtt gtaaaatata aataacaaaa gataatcaaa taacaacttg acgtcaaaaa
     9481 ataaagataa atgataactt ttgataataa aatatattta agaggaaaag gttatggaaa
     9541 aattattaca agaaaagtta cttccagtag cggctagatt gggtaataat aaagcgttgg
     9601 tttctattcg agacggtatt actctaacta tacctttatt gttgataggt tcattactaa
     9661 tggttattgc aagttttcct attccaggat gggaaaaata tctgggtgat attggtgttg
     9721 ctgactattt atggaagggt gttgatagta gttttggatt acttggtctt gtagctagtt
     9781 ttggtatcgc ttactttatg gctagacaat acaaagttga tggtattcct gctggtattg
     9841 tgtcattatc atcttttatt acagttacgc ctttcattac aggagaggct ggagcaggaa
     9901 tgcctaccgc tttcatggca tcaaaaggtt tatttgttgc tatgatttta ggattgatta
     9961 atggctatat ctaccaatgg tttataaatc ataatataca gataaaaatg ccggatggtg
    10021 ttccaccagc agtatctaaa agctttagtg ccattattcc tggtgcagtg actattgttg
    10081 gttggttgat tgtttatgca actttagata aattaagttt acctaatctt catgaaattg
    10141 ctcaagtagc tttgggaggt ccacttggac ttttaggaaa taatgttatt ggtcttctta
    10201 tcttaatttt ccttaatagt agtttttggt ttgtaggatt acacggagga aatgttgtta
    10261 atgcagttat gaaaccgtta tggttagcta atctagatgc aaataaagta gcttatcaaa
    10321 ctggagaaac tcttccaaat atttttacta gcgtatttat ggataatttt gtattcatag
    10381 gtggcggtgg tgcaaccata ggtttagttc ttgcgttagg atatttagca cataagaaga
    10441 aagctagtaa acaactaaaa actttggcac ctataactgt tatacctgga ttatttaata
    10501 taaatgaacc agcaatgttt ggtgttccta ttgttttgaa cattttgtta ctagttccat
    10561 ttatcttagc tccaatgttt aacttactag tagcgtgggg agcaatggca tcaggcttgg
    10621 ttccgctaac ttatacagat ccaggttgga ctatgccacc tgttataagt ggtttacttg
    10681 ctacaggaag tatttctggt tcattattac aaattgtatt gattgttttg gatgtcttac
    10741 tttatttacc atttgtaata gctattgaaa aacggtttaa gttattggag gattgagaat
    10801 gaaacgttta attagtgcaa atccatctga gatattacag atgaatgctg aagaattaaa
    10861 acaaagtatt ttagcaagtg aaggtagagt tgttctatct gaaaatgtag tcactcgtga
    10921 gacatttgtt ggggatataa ctaattctga aattgctaga gcttttggag ctgatatgat
    10981 tttattgaat tgtgttgatg tttttgagcc taaaatttat gctttggata gttcaggtga
    11041 tgatgttatt catcgcttac accagctcgt tgcttgccca attggtgtaa atttggaacc
    11101 gattgaccca tctgcaaaga tgctagagga aacacaggaa attgttgcag gtcgtgttgc
    11161 tagtgttgaa acattgaagc gaatagagga gttaggtttt gactttgtct gtttgactgg
    11221 aaatcctgga acaggagtta gcaatcgaga aatcattaag gctgttcaaa ctgctaagga
    11281 aaacttttct ggtttgatta ttgcaggtaa gatgcacggg gcaggagtga atgagcctgt
    11341 ggcagagctt tctgtcgcag agcaattgtt ggaagcaggt gcggatgtga tacttgttcc
    11401 agcagttgga accgttccag cctttcatga ccaagagttg cgtgaagtcg ttgatctcgt
    11461 tcatagtaag ggtggtcttg tattgagtgc tattggtact agccaagaaa catctgatac
    11521 agatactatt aaggaaattg cacttagaaa taaaatttgt ggagttgata ttcaacatat
    11581 aggtgacgca ggatatgggg gactggcaac agtcgataat atttatgcat tgagcaaggc
    11641 aattagagga gtgagacata cagtatctcg cttggctagg tcagtaaata ggtgataaag
    11701 gagtaagcta tggctaaagt aacaattatg ttagcatgtg cagcaggtat gagtacaagt
    11761 ctgctagtga caaagatgca aaaggcagca gaagataagg ggttggatgc agaaattttt
    11821 gcagttccag ctcctgaagc agaagaaatt gtagcaacaa aagaagtaaa tgtgttgctt
    11881 ttaggtcctc aagttcgcta tttactaggg gactttcaag aaaaactaaa agatagacag
    11941 attcctgtgg cggttattcc gataacagat tatggaatga tgaatggttc taaagtctta
    12001 gatttagctg aaagtttatt agactaagat tgaggagaat gttatggatg aaagtaattt
    12061 agaatctgta atggggctaa ttatgtatgg tggggaagcc aaaagtaatg ctatggaggc
    12121 tattcaggca gcaaaaaaag gggatttctc taaagccaat cgaagattag ctgatgcgaa
    12181 tgctgcctta ttacaggcgc ataaggctca aacagaaatg ttgacaagag aggcacaggg
    12241 ggaagaaaca tcaattagcc tcttgatggt acacgcgcaa gatcatttaa tgacgagtct
    12301 gacttttgtt gacttggcga aagaagtggt agaagtatac gaacgatttg aaaaaaatta
    12361 ggagtttagt atgaatacaa tgttggataa aatgcaagaa aaactttctc caattgcaat
    12421 gaaagttggg aatcagaagt ttttagttgc tttacgtgat tcatttgtgg ggactatgcc
    12481 tgttattatg acaggttcca ttgctttgtt attaaatgct tttctagtgg atttaccaca
    12541 acaatttcac ctagaaagta ttacgaaaac ctttcagtgg cttgttgaca tcaataattt
    12601 ggtattcaag ggaagtatac caattgtttc cttgttgttc atctattgct tgggagtgaa
    12661 tatcgctaag atttataagg ttgatacagt ttctgctggt ttggtatcgc ttgcttcgtt
    12721 tgtcatttcg attggaagta cagttacaaa gagtttccct ttggcaaatg taggagatgt
    12781 gaaattagat caaatcttac aaggaattga taatctagca tttgatggta aaaatctgat
    12841 ggtaactatt gggaatgtga ttccaggaaa ccatattaat gccagaggct actttacagc
    12901 catgatgatt ggatttttag cctctattat tttctgtaaa gtaatgaaaa agaactgggt
    12961 aatcaagtta ccagattcag ttccccctgc gattgctaag ccgttcactt ctatcattcc
    13021 aggatttatg gcgatgtata tagtagccat cttgacttat gttttccatt tacttagcaa
    13081 tgacttattg attgattggg tttacaaggt gttacaaacg ccattactag gtttgtctca
    13141 aagtttcttt gcagttattc tgatgatctt tttaaataag ttattctggt tttttggtct
    13201 ccatggagga aatgtattgg ctcccatcat ggaagggctg tttggagttg ctatgttagc
    13261 gaatctggat gctttccaaa aaggtgaacc gattccttat atatggacaa gtgggtcttt
    13321 tggggcgttt gtctggtttg gaggattagg attggtactt gctattttaa ttttttcaag
    13381 aaacagtcat tatcgaaaag ttgctaaact tggtctagca ccagttctgt ttaatattgg
    13441 tgagccggta aattatggtt taccagttgt cttgaatcct ttgctattta taccatttgt
    13501 acttagcccg gttttcatgg caacggtagc ttactgggca acaagctggg gtcttgtttc
    13561 acctgttaca caaaatgtta cttgggtaat gcctccaatt ttatatggtt tcttctctac
    13621 agcatttgat tggcgtgcca tcatcttatc agttgtttgt ttgattatta gtgtcttgac
    13681 ttatttccca tttgtgaaaa tggcagataa aactgaattg agttaatggt cttacttgcg
    13741 ttttttgtga taaaatagaa atagattacg tgtaagattg agttaggtgt aggatttctt
    13801 atctccacta aaattgttat tagacaaagg tttatagttt attgaagttg gaatagtaca
    13861 ctgtaacttc taaaatagta ctagaaaatg atttgaattt cctaatcgat ttagtcatat
    13921 tttagttcat ttttctataa aacataacaa gaatgttatt gttttatata gagagattga
    13981 tatagaaagg ggtgcagtaa aggtagatat cttcttgtgc ctcttttgcc atattagaaa
    14041 ggagatttta tggttcagac aaaacagcca aatattattt tgattgttgt agatcaaatg
    14101 agagcagacg ccttatcctt gaatagtaag gataagctag ttagcactcc aacattagat
    14161 atgatggcta gtgtaggtta taattttgaa aatgcctatt ctccagttcc ttcttgcgtt
    14221 cctgctaggg cagctttatt gactggctta gaccaagata aaagtggacg agttggttat
    14281 caagatgagg tgccttggaa ttttactaat actcttccaa aagtctttaa agatatgggt
    14341 tatcaaacag agtgtattgg taagatgcat gtttttcctt ccagacagag acttgggttt
    14401 gatcatgtct tacttcacga tgggtatcta catgttgata gaaagtatga taaggcttat
    14461 ggaagtcaat ttgattatgc tagtgactat ctagcctttt taaagggtaa agttggttat
    14521 gatgttgatt tgattgatga cggaatggat tgtaattctt gggaagctag accttgggat
    14581 aaagatgaaa agttacatcc aacaaactgg gttgtgagtg agtccatttc atttttacaa
    14641 agaagagatc caacggttcc tttttttctc aaaatgtctt ttgaaaaacc acatgctcca
    14701 ttaaatcccc caaaatacta ttttgatatg tatatggaac gcttgcctca atttctcgat
    14761 ttgcatatcg ggaattggga agtattagaa aagcaaattc cgtctattta tgctttaaga
    14821 gggaaattaa aggaagatga tcaaagaaga atggttgctg cttattttgg attgattact
    14881 catatagacc atcaaattag tcgctttttg actgccctaa aagaatttcg tcatgataaa
    14941 gatacgatta tctggtttgt ttcggatcat ggagatcagc ttggtgaaca ttatctgttt
    15001 agaaagggat atccttatca gggaagtatc cacattcctt cgtttattta cgatccggct
    15061 ggattgatag ctggtaatag gggaacaatc aagcaattag tgaaaattca agatattttt
    15121 ccttcactcg tggatttggc aggaggaact actacagatg aactagatgg acggagtgtt
    15181 aagaatttat tatttggaca gtacgagggg tggcgaacag aatttcatgg tgaacatgct
    15241 ttaggaaaag attctagtca atatattttg acagaccagt ggaaatttat ctggtttcct
    15301 gttttaaatc attatcagtt atttgatatg aaaaaagatc cgcatgaaat gaatgatttg
    15361 tatccaagtg aaaaatacca acctattgtt cgtcagatga agaaaaaatt agtaaacttt
    15421 cttagatata gagaagaagg ttttgttgtg gatgaagagt tagttcctgt tgaactttct
    15481 aaaataacgc caactctaac gaaaacgggg gatagtcaat catgaaaatg aaaaaaatca
    15541 agggtgggac atttatgatg ggaacaaatt ctgaagaggg ctttttagat gattttgaag
    15601 atcctcaagt cgctgttagt gtaaaggatt tttccattgc ggatactcca gttacgaatc
    15661 aagaatttgc tcaatttgtg aaagaaacag gctataaaac actagctgag cgacaagagt
    15721 ggtcttttgt ttttatattg ttcgttccgg aggcagaaag ggagggatat cctcatcctg
    15781 ccggggctcc gtggtggtta caagttccga acgcttgctg gaaacatccc tacggtgaga
    15841 acagtaatct agtgggttta gaagaccatc cagtagttca tgttgcttta gaagatgcat
    15901 tggctttctg taattggagc ggaatgtctt taccgactga agcacagtgg gaatacgctg
    15961 ctagaggagg aagacaatct gaatatcctt ggggagatac tcttttagaa ggtggatatt
    16021 atcatgccaa tacttggcaa ggaagatttc cttatgaaaa tactggctta gatggattta
    16081 taggaacggc tcctgtctat gaatttttac ctaatgattt tggtctatat caaatgattg
    16141 ggaatgtttg ggaatggtgt cgcaatccga gatatacctt attagctagt tttaatgaag
    16201 atgactatga gttgccaaaa tatgggatac aagatgagga gtatgctatc agaggaggtt
    16261 cctttttatg tcattgttct tattgtaatc gataccgagt agctgctaga aatggatgta
    16321 tttctacttc cactagtagc catctaggtt ttagatgttt gaaagaatag gatggactta
    16381 aaaagtggtt gagattattt attttctaat cattataata gctagtggat tgggttctat
    16441 atcaggcatg ggtggtggaa ttataattaa gccacttatg gatagttttg gataccattc
    16501 ggtcagtgat attgcttttt attctagttt ctctgttttt ataatggcga ttatttcaac
    16561 aaccaaaaga ttttcacaaa gtaaagagat aaaatggaga ttgattttta cggtatcctt
    16621 ttcttctgtt ttaggaggat ttctaggtca tcttattttt caagttttgt tatctcaatt
    16681 atcagtacgg ctagtatcca ttgttcaaat gattttacta tttgtgatgc tacttgtatc
    16741 atttgtttta acagatttta aaaaaactta tcaatttgat aagataggat tctatatgat
    16801 ttgtggtctt ctattgggct tgatttctag ttttttaggg attggtggag gtccgctcaa
    16861 tgtatcttta ttgatggtgt ttttttctat ttcgataaaa gaagcaacga tgtattctct
    16921 tgcaattatt ttcttttccc agctgtctca tttggctaca attgttgtgg ttacaggttt
    16981 aaatcagtat catttagcac ctgttccagt tatttttctt gcttctatat gcggaggggt
    17041 attggggacg gttgtatcaa aagtcttacc tgaaaattgg gtaagatact gttttaaagg
    17101 gatgttattc tttgtcatgg gaatgacttt atataattta tttcatattt tgtaaggtca
    17161 gtgtgaaaat atttaaatag acttcctgta aaaactggat ttaacgccct ccatttgtca
    17221 aattaagcta gacagtctta ccaactcaga aaataacctg atgaggtatt tggtatccaa
    17281 aggatttagg tgggatgtga tttcttgagg ctgggaaaaa gtctgtaaaa ttaaaaaatg
    17341 cataatatca ggtgttggaa aaactttgat actatgcgtt ttattgtggg aatatttatt
    17401 tcattttctc ctgaaattga gttcttgccc agcctaaaat tcttgactga cttcgttgaa
    17461 atctgtctgc tttggcaagt catgacacct taaaagtcta tttgaatgtt cgttgagaca
    17521 ccgctatctt ggacatccta gattcgcaaa aaagctctca ctatcgtgat gattggaaat
    17581 atctttccat tttgaaaact cttttccaca gtcaaacgta atagatttaa agaggttcac
    17641 tagaaattgt gccagccacc cttggatgga ttctgccata tcctttgcct tacgactctt
    17701 ggtcttcaaa ctgacaatca attgactata cctgttcgct cacaaatagg agagaacttt
    17761 ttacgaaaat ctaatgaata tgccataaga acattatacc gcaacgtgta ctatttttgg
    17821 ttcattttac tatagaaact attgaagcac ctgtacgaaa atatatcatg aaaaagggga
    17881 gatagaaagc aaacagcctt gaaatcaatg ttgactgcga ttattaacct gaatcagccc
    17941 ctcaaaaggg actgtatatg aatgaacgtt accagtgttt aaaaactaaa gaatatcagg
    18001 cacttttatc ttccaagggt agacaaattt tcgctaaacg taagattgat atgaaatctg
    18061 tctttgggca gataaaggtt tgtttgggtt ataagagatg tcatctgaga gggaagcgtc
    18121 aagtgagaat tgacatggga ttcatactca tggccaacaa cctgctgaaa tataataaga
    18181 gaaagaggca aaattaaaaa gctagagttc cgcaattggg aatctctagc tttttgtttt
    18241 ctgagaatca tcttgactca gactcttttg actaatgtta ccaaaaagat aaagtaactt
    18301 ttaaccttat ttatcgtcgc cactcaacat gtttttaaca ccttctacag caccttctac
    18361 agcgtctttg gcatcttcgg cgacttcttt tactttagaa acaacttttt cagccgctcc
    18421 ttctttttcc attttttcat caccgatggc tttcccaaca ccttctttaa tagaaccttt
    18481 agcttgattt aatttttctt ctactgacat gataatttct cctgttatat ttattttatc
    18541 ttagtttaca cgagtgtttt cgtgagatac tacaccattt gctgcacctt taacagcttc
    18601 tacaccttcg ctaacttttt cttgaacagt tgagaaacca gatccaagac cagatttagc
    18661 tttttcgaat tgttctgaag tgaattctcc tgttgattca gcaacgtcag atacgcgatc
    18721 ttgaaggctt actgagtctg cttcatgctg ttctttagtt ttgatgtcga caacgtttac
    18781 gttgatttca acaatttcca agtcagtcat tttagcaact tctgaagata cgatttctct
    18841 gatttctgaa tataaagctg gaacattttt ttggtactca acaataacgt ttaagtcaac
    18901 tgcaacttgt gttttaccaa cttctacgtt aacaccactt gttacgtcat cgctgttaac
    18961 gattttttct ttaagatttg agaagaaacc accatcgatt cccaaaagac ctgaaacgtt
    19021 ttctagtgaa agaccaatga ttttttggat aactttatct tcgtaagtaa gttccccttt
    19081 gatttcgtga gctacaacag tagcatcttt cttttctacg ttagtgtttg tgtttttttc
    19141 gtttgacata tgaaactcct ttaattaaat tagtaatttt tattttttta tttatctata
    19201 tagttttttt cgatatataa tccagctgca actcccagtg ctcctaaaat caatacaaat
    19261 attgttttga agaagccaaa ggagacaatc aaacaagcca gaaatacgcc tatgagacca
    19321 gcgataattg gatatcgata ttgtttaagc cattccattt tttacttcct tacttcacac
    19381 gactaacagt ctttttgttt tgaggttttg gttggtaatt ttttactgca acttcaagtt
    19441 ttacttgacg ctcaatacca aaaaactgct tcaatccatt agttatttca ttttgaatta
    19501 tttggcatct gtcagcgatg ttgtctgaag gaagaatttt accttctaca tgaacgaaac
    19561 atttattttt tcgtaaattt acatgaacag ttgggttctt gatcaatcta tgatcactca
    19621 ccaaacttct aacaaaacct tcgattgccg aattctttaa ttttaatgta tcgtttttag
    19681 tttcaagttg gatttccaag taacgtttag gataaaacat cacaactaaa atggataata
    19741 aaactaaagt tgatagaacc actgtccccc aaaagacata tctagcaaga tagaattcaa
    19801 ctacggagtt ctgtctccag ctaagtagat gaatacctag atcactaact tgatgataat
    19861 ctatcaaaac aggaaggaaa attgtcaaga ttaaaataca gaaaataatg aaacatattt
    19921 tctttgcttt tgacatatac aatcctttcg atttaacatt taaactattt ttcccgtcat
    19981 tgatttaaaa atagtttgct aactttactg gcgaaaagtt tactttctac ctgtaaagaa
    20041 tgacactaca gtaatcacaa tcgctgcacc tacaatagat gggagcaaag ccattccagc
    20101 gattgctgga ccccaactac ctaaaagaga ttgtcctgca tatgccccga ctaaaccagc
    20161 gaatacattt gcgatgattc ccatagaact acttttttag tgattttacc tgccaagaga
    20221 ccaataagac ctccagcaat aattgatcac aacactgcct accctccttt tttattttaa
    20281 tatcaaaaaa tcaatttctt tgattattac tattatataa ctttaatata gaaaagtcaa
    20341 ttatttcgat tgttattatt atataatttt taaaaatcaa attctttaat tgttgctatt
    20401 atataatttt taaaattaaa aatataatct ttagacttga atttgattct gtattcacgc
    20461 cctcaataga cggtaaaata agaaaattgt ttatatattg tctccgtagt gttattatac
    20521 gaaataaaag attttaggaa aagtcgttat atcatgctat acctattctt tgtggtataa
    20581 ttgcaagagg tttaatccga taatttataa agagagaaag atattcatga gagatttatt
    20641 atctaaaaaa agtcataggc aattagaatt attagaatta ttatttgaac ataaacgttg
    20701 gtttcatcgt tctgaactag cagagttatt aaattgtaca gaacgtgcag tcaaagatga
    20761 tctatcccat gttaaatctg cttttcctga cttgattttt cattcttcta ctaatggtat
    20821 acgcattatt aataccgatg atagtgatat tgaaatggtt taccatcatt tctttaaaca
    20881 ttcaactcat ttttcgattt tagaattcat cttctttaat gaaggttgtc aagctgagag
    20941 tatttgtaaa gaattttata tcagttcatc ttcgctctat cgtattatta gccaaatcaa
    21001 taaagtgatt aaaaggcaat ttcaatttga agttagtctg acccctgttc aaatcattgg
    21061 aaatgagaga gacattcgtt acttttttgc acaatatttt tcagaaaaat attatttcct
    21121 agaatggcca tttgaaaatt tttcatcaga gccactatct caattgttag aattggttta
    21181 taaggaaaca agctttccaa tgaatttgtc aacgcataga atgctaaagt tgctcctagt
    21241 tacgaaccta tatagaataa agtttggtca ttttatggaa gtagataaag attcttttaa
    21301 cgaccaaagt ttggattttt taatgcaggc agaaggaata gaaggtgttg ctcagagttt
    21361 tgaatcagaa tacaatatct ctttagatga agaagttgtt tgccaattat ttgtgtctta
    21421 ctttcaaaaa atgtttttca tagatgaaag tctctttatg aaatgcgtaa aaaaggatag
    21481 ttatgttgaa aaatcttacc atctattgag tgattttatt gatcagattt cagtcaagta
    21541 tcagattgaa atggagaata aggataatct gatttggcat ctgcataata ccgcacatct
    21601 gtatcgtcaa gagttgttta ctgagtttat tttatttgat caaaaaggga atacaatcag
    21661 gaactttcaa aatatttttc caaaatttgt ttcagatata aaaaaagagc tttctcacta
    21721 tttagagact cttgaggttt gttctagttc aatgatggta aatcatctat cttatacctt
    21781 catcactcat accaaacatt tggtgattaa tttgctacaa aatcagccta aactaaaggt
    21841 tttagttatg agtaattttg atcagtatca tgcaaaattc gttgcagaga cactttctta
    21901 ttattgtagc aataattttg aactggaagt ttggactgaa ttagaattat caaaggaatc
    21961 tttagaagat tcaccttatg atatcattat ttctaatttt attattcctc ctattgaaaa
    22021 taagagactc atctattcaa ataatataaa cacggtctca ctcatatact tgttaaatgc
    22081 catgatgttt attcgattag atgagtaacc aaaaataaca aaaaaacgct atttcgcgtt
    22141 tgaactgtac ctcaaaagtt agacagaaaa aatctaattt ttgggggtgt ttttgttaag
    22201 aaaagacctt caatcattta agcaaaatgt acatctagat ttatagccct ctaaaactct
    22261 tgcttttttt gtagaagata cgaaaaaagc cataaaacca aggcttttcc tgttttatgt
    22321 agatgtttac acatgaaaat tgaagtattt tcaaaagcta attggagtga ttttattcat
    22381 gatgggataa atgatctggc caaaaatgat tgagaaatag ttgcttaaaa agcatttgca
    22441 tgatactata tattgaaagg aggtgataat atggtagaac aaagaaaatc aattaccatg
    22501 aaagatgttg ctttagaagc aggagttagt gttggaactg tttcacgtgt aattaataaa
    22561 gaaaaaggca ttaaagaagt aactttgaaa aaagtggaac aagcgattaa aactttgaat
    22621 tacattccag attactacgc tagaggaatg aaaaaaaatc gaacagaaac gattgcaatc
    22681 attgtaccaa gtatctggca tcccttcttt tcagaatttg ctatgcatgt ggaaaatgaa
    22741 gtctataaga gaaataacaa attactctta tgttctatca atggtacaaa tagagagcaa
    22801 gactatctgg agatgttgcg tcataataaa gttgatggag tggttgccat tacctatagt
    22861 ccaattgaac attacttgac gtcaggaatt ccctttgtta gtattgaccg cacatactca
    22921 gatattgcca ttccttgtgt ttcatcagat aatgatgcag gtggaagaga agcagctaaa
    22981 caattaatta gtaaaggatg tcagcattta gcctttgtgg gcggacataa tacaaccatt
    23041 aatgaaacca aacgtcgtag aatttcattt gaaaagtatg tccaagagca taaaatacct
    23101 cttagtattt ttgatttgga tgagacagtt actgactatt atggaaagct agagagtttc
    23161 ttggaagaaa attcttctat agatggaatt tttacaatca acgattttac agctttggat
    23221 gtgattgaaa tactagaaaa aaatggtaaa cgtattcctc atgatgtcca aattattgga
    23281 tacgatggaa ttaaaatggc tggagataga gattatctac tttcaactat tgaacaacca
    23341 ttggaagaaa tggcaaaaga agcggttcgt attttgtttg atataattga tggaaagact
    23401 gttaatttgc agacaatcct accagtaaaa tttgttgaag gaaaaacaac aaaaaatgaa
    23461 aataagtctt gacagaaagc gctatcaatg atagaatgaa ttcagataaa aaagatttat
    23521 ttttaaaaca aaaatgaaac gtttcaaaaa agaaataaag agacagcgcc aagcgctatc
    23581 ttttctagaa aaaaatgaaa cgtttcaaaa ggaggttgct atgaatagca aagcgaagca
    23641 agtttctctt tgggaaagaa tcaagaaaca aaaactcttg ttattgatga ctgtccctgg
    23701 tttagtttta acctttatct ttaaatacat ccctatgtat ggggttttaa tcgcatttaa
    23761 agattacaat cctttaaaag gaattttagg gagtgattgg attggttttt ctgagtttac
    23821 aaaattcata tcctctccca actttggtat cttgttagcc aacacattaa aattaagtat
    23881 ctatggttta ttgcttggct ttttaccacc aatcattctt gctattatgc tcaatcaact
    23941 cttgagtgaa aaagtcaaaa aacgaattca gctcatttta tacgcaccaa actttatctc
    24001 agtcgttgtt attgtcggta tgattttcct cttcttttca gtgggaggac caatcaacaa
    24061 ttttctttct atgtttggaa tgaaggctga cttcttgaca aatccagact tctttagacc
    24121 tttatacatc tttagtggta tctggcaagg aatgggctgg gcttcaacgc tctacacggc
    24181 aacattggta aatgtagatc cagccttagt agaagcagcc cgactggatg gagccaatat
    24241 cttccaacga atctggcaca ttgatattcc agctcttaag cctattatgg ttatccaatt
    24301 tgttttagct gcaggtggaa ttatgaatgt cggatatgaa aaagcattct tgatgcagac
    24361 atcgttaaat ttgccaactt ctgaaattat ctcgacatat gtctataaag ttggtcttgt
    24421 atcaggagac tattcttact caacagcggt tggtttgttt aatgcagtga ttaacgtagt
    24481 attgcttgtt gcagttaacc aaatcgttaa acgcatgaat aatggtgaag gaatttaagg
    24541 aggaaagtat gaaaaattcg attatggata caaaatttga tagacgtatc ttactcttaa
    24601 ataaaatcat tattgtcttt atcgttttga tgactttgct tcctttactt tatatcgtcg
    24661 tagcatcctt tatggatcct aaggttctgg ttagtagagg gattagcttt aaaccagccg
    24721 attggactgt agaaggttac cagcgtgtat tcagtgacca atctattcta agaggtttta
    24781 tcaattctct actatactct tttggatttg cagctttaac agtattgcta tctgtgttta
    24841 cagcttatcc tctttctaag aaagacttgg ttggacgtcg ttggattaac tacttcttga
    24901 ttgtgactat gttctttggt ggtggtttag tcccaactta cttgctcgta aaagaattgg
    24961 gaatgctcaa tactccatgg gctatcattg ttccaggtgc tgtcaacgtt tggaatatta
    25021 ttcttgctag ggcctatttc caaggattgc ctgaagaatt agttgaagct gctgtcattg
    25081 atggtgcaaa tgatttacag attttcttca aaatcatgct tcctcttgca aaaccaatta
    25141 tgtttgttct cttcctttat gcttttgtag gacagtggaa ctcatacttt gatgcaatga
    25201 tttatatcaa ggatccaaac ttggaaccat tgcaacttgt acttcgtaaa attctcattc
    25261 agagccaacc aggtcaagac atgattggag cacaagcggc tatgaatgaa atgaaacgtt
    25321 tagctgaatt gattaaatac gcaactattg tcatttccag cttgccattg attgttatgt
    25381 atccattctt ccaaaaatac tttgataaag gaattatggc tggttcactt aaaggataaa
    25441 aaaagaaaaa ataaaaggag ttttctcatg aaattcaaaa cattctcaaa atcagcagtt
    25501 ttgttgacag ctagtttagc agtacttgca gcctgtggct caaaaaatac agcttcaagt
    25561 ccagattata agttggaagg tgtaacattc ccgcttcaag aaaagaaaac attgaagttt
    25621 atgacagcca gttcaccgtt atctcctaaa gacccaaatg aaaagttaat tttgcaacgt
    25681 ttggagaagg aaactggcgt tcatattgac tggaccaact accaatccga ctttgcagaa
    25741 aaacgtaact tggatatttc tagtggtgat ttaccagatg ctatccacaa cgacggagct
    25801 tcagatgtgg acttgatgaa ctgggctaaa aaaggtgtta ttattccagt tgaagatttg
    25861 attgataaat acatgccaaa tcttaagaaa attttggatg agaaaccaga gtacaaggcc
    25921 ttgatgacag cacctgatgg gcacatttac tcattcccat ggattgaaga gcttggagat
    25981 ggtaaagagt ctattcacag cgtcaacgat atggcttgga ttaacaaaga ttggcttaag
    26041 aaacttggtc ttgaaatgcc aaaaactact gatgatttga ttaaagtcct agaagctttc
    26101 aaaaacgggg atccaaatgg aaatggagag gctgatgaaa ttccattttc atttattagt
    26161 ggtaacggaa acgaagattt taaattccta tttgctgcat ttggtatagg ggataacgat
    26221 gatcatttag tagtaggaaa tgatggcaaa gttgacttca cagcagataa cgataactat
    26281 aaagaaggtg tcaaatttat ccgtcaattg caagaaaaag gcctgattga taaagaagct
    26341 ttcgaacatg attggaatag ttacattgct aaaggtcatg atcagaaatt tggtgtttac
    26401 tttacatggg ataagaataa tgttactgga agtaacgaaa gttatgatgt tttaccagta
    26461 cttgctggac caagtggtca aaaacacgta gctcgtacaa acggtatggg atttgcacgt
    26521 gacaagatgg ttattaccag tgtaaacaaa aacctagaat tgacagctaa atggattgat
    26581 gcacaatacg ctccactcca atctgtgcaa aataactggg gaacttacgg agatgacaaa
    26641 caacaaaaca tctttgaatt ggatcaagcg tcaaatagtc taaaacactt accactaaac
    26701 ggaactgcac cagcagaact tcgtcaaaag actgaagtag gaggaccact agctatccta
    26761 gattcatact atggtaaagt aacaaccatg cctgatgatg ccaaatggcg tttggatctt
    26821 atcaaagaat attatgttcc ttacatgagc aatgacaata actatccaag agtctttatg
    26881 acacaggaag atttggacaa aattgcccat atcgaagcag atatgaatga ctatatctac
    26941 cgtaaacgtg ctgaatggat tgtaaatggc aatattgata ctgagtggga tgattacaag
    27001 aaagaacttg aaaaatacgg actttctgat tacctcgcta ttaaacaaaa atactacgac
    27061 taataccaag caaacaaaaa ctagaggttg attatgggag ataagaaata cacagtagaa
    27121 aaagccaatc gttttatagc agaaaataaa catctcgtta atactcaata taagcctgaa
    27181 gaacattttt cagctgagat tggttggatc aatgatccaa atggatttgt ctattttcgt
    27241 ggagaatacc atctctttta tcaattctat ccatatgata gtgtttgggg gcctatgcac
    27301 tggggacatg ctaaaagtaa ggacttggtg acttgggagc acttgccagt ggcacttgct
    27361 cctgaccaag attatgaccg aaatggttgt ttctcaggct ctgccattgt caaggatgat
    27421 cgcctctggc tcatgtacac tggacatatc gaagaagaaa ccggtgtccg ccaagtgcaa
    27481 aatatggcat tttcagatga cgggattcac tttgaaaaga tttcccaaaa tccagttgca
    27541 actggatcag acttgccaga tgagttgatt gctgctgatt tccgtgatcc aaaactcttt
    27601 gaaaaagatg gacgctatta ctccgtagta gctgccaaac acaaggataa tgtgggctgt
    27661 atcgttctac tagggtccga taacctagta gaatggcagt tcgaatccat ctttttaaaa
    27721 ggggtagaac accaaggctt tatgtgggaa tgcccagatt acttcgagtt agatgggaaa
    27781 gattgcctta ttatgtcacc catgcgttat cagcgtgagg gagactcata tcataacatc
    27841 aactcatcgc ttttgttcac gggtaaggta gattggagag aaaaacgttt tatcccagaa
    27901 tcagttcaag aaattgatca tggccaagac ttctatgcgc ctcaaacatt gttggacgat
    27961 caaaatcgtc gtatcctgat tgcttggatg cagacatggg ggcgtaccct tccaacccat
    28021 gaccaagaac acaagtgggc atgtgccatg actttaccta gaattctaag attggaagat
    28081 ggcaaactaa gacaattccc tgttaaaaaa ggccaatatc aaatccaaat agataaagat
    28141 tgtcattacc acttaggaaa tgatacagat tatcttgaat ttggttatga cagtaatgtg
    28201 cagcaagttt acattgatcg tagccatctt attcaaaaaa ttctaggtga agaagaacag
    28261 gacactagtc gacggtatgt agatattgaa gctaaagaat tggaagttgt tctagataaa
    28321 aattccatcg agatttttgt caatcaaggt gaagcaagct tgactgcaac ttattactta
    28381 acggtgccag ctgagctatc acgaattgat taaaaattaa gttatttctc ctaaagaaaa
    28441 agttctcttt ctaaaatagt ggaaagagga ctttttgtgt tttgggtata taagcttagt
    28501 ttatggtatt tgtaaaattg gtgttggatt atgatttaaa ctagttttct aaagaatttg
    28561 aaaaaaattt tatttaagca aaaaaagccc tatattataa gacttttcct gttgtattta
    28621 gatgccccct acagggatcg aacctgtgac ccacggatta agagtccgct gctctgccag
    28681 ctgagctaag gaggcaaaga aaaaagctgt attggtgccg aaacttcacg gtttgtattg
    28741 aacccgcgca attaagcagg tgggcaactc gctctaactg aagctgtttc cgtgtgagac
    28801 ggcctacatg ctgttagaag acttttgttt ccctaataat acaaaaaata gtcggtcaac
    28861 acttaagtgt gaagtcgtac accacagcgt ttctatactt atatgatacc actttttcaa
    28921 aaaaaatcaa gaggaaagtg caattttttg aaaaggattt cagatttttc gcaaacggtc
    28981 gatagcttcc tttctttgag ccaaagcccg ttcatattta ccagtatctt ctgcttggaa
    29041 atagtgatga ttacgaattt tttctggcag atagtcttgc tttacccaat ttccaggata
    29101 gttgtgtgga tagagatagt cttgggcatt ccccagttcc ttgcttccac tgtagtgccc
    29161 atcacgtagg tgtcgcggaa taggcaagtg ccctgatgtt ttgaggtcag caagtgcctt
    29221 atccatagct acataggctg agttggattt tggagaaagg gccaaatcaa tcacgacatt
    29281 ggcaatgaga atgcgggctt ctggaaaccc aatcttctgg gcagcatcca gagcagtcac
    29341 ggtatgaatc tgggcctcag gattggctaa gccgatatct tcataggcga taacagtcaa
    29401 gcgacgagcg agactaggca gatccccagc ctcaatcaag cgggcagcat agtggagact
    29461 ggcatccaca tctgagccac ggatagactt ttgcagggca gatagaacat catagtgacc
    29521 gtctccatcc ttgtccatag tgatgtagct tctctgaaga ctattttcca tgatgtctaa
    29581 ggtgatgtgg cgaatgccct cgtcattctc aggggtagag agaacagcca agtccagtga
    29641 gttaaaggca gagcgaaggt ctccgtttgt agaggttgcg atgaaatcca gcgcatcctc
    29701 atctagttct attggaaaat caaaaccacg ttcagggtta cttagagata tctgcagggc
    29761 ctctttgacg tcttggttag acagaggttc caactcgaaa atttgaacac ggctacgaat
    29821 ggcaggagtg acagagaaga aaggattttc agtcgttgct ccaatcatga tgaccagtcc
    29881 actttccaag agaggcaaga ggaagtcttg cttggtctta tctagtcgat gaatttcgtc
    29941 tagcaatagg acgagaccac cagaaaattt agcttcttcc gagatttctt gcagtcgctt
    30001 tttactatca actgtcgcat tgaaagttcg aaaggcatac ttggtcgttc cagcgatggc
    30061 agaggcaata ctggttttgc cgattcccgg agggccatat agaatcatgg aggacaggcg
    30121 gttggcttcc accatgcggc ggatgatttt tccaggtccg accagatgct cctgaccgat
    30181 gacctggtcg atggttttag ggcgcatgcg aagcgcgaga ttgtctggca tagcagtcct
    30241 ttctaacgtg gatttgagta gaatgactca tctactatat cttactatgt ccattctagc
    30301 ctattagttg tgatatttca atggttttgt aataatcagg gagtgggata gaatcttttt
    30361 tactatttaa tttaatgagg agaggtatca gcatgagaga tttgattttc cttaaagctc
    30421 aaaataggat agttgagcct aaagaagtgg aagtgctgac ttgagaaata atattgctga
    30481 atgtcattgt atgaactata atgaaaagag aggtgataag caatggaaat gatggaccaa
    30541 gtcaggaaat tttgattttt acaaaacaaa ttcgtcattg gattcttagt gatcaagtta
    30601 tttcagggaa aagaaaactt ttcttccggg aagatactcc aaaagagatt ttagatttgt
    30661 acgaaaacat taaatctaaa cttgattttg cttaccaaga agttcattct aataatgggt
    30721 tgaaaaaata tgaaaaatag aataattgat gtttttgaag tagtaaatcg cctccttgta
    30781 ctaactgttg aaaatcctga tttcgaagac ttgagagtta atcatactca atgaaaatca
    30841 aagagcaaac taggaaacta gccgcaggct gtacttgagt acggtaaggc gacgttgacg
    30901 tggtttgaag agattttcga agagtatcag tttgtaaaaa ttggagataa aaaatataga
    30961 gtacgcagtg ttcctatgat tcattcaact ccgcctcaat ctgtcttaga tcgagatact
    31021 tttacaattg actatacaga tgatgaattg ctcgataaag aagcagtttt tactactcat
    31081 tagaaaaata ggtatgaata aattggcttc ccttagaacc acatctaggg gcttttatgt
    31141 ataatagaat aataagtatc actcctttac aatacgtgta acacgtgtta taatggtgtt
    31201 gtcaggaggt aaaagcgcta tgcctatgac acaaaaagag atggttaaac tccttacggc
    31261 ccatggttgg ataaagacta gaggcggtaa aggttcccat attaaaatgg agaagcaagg
    31321 ggaaagacct atcacaatcc ctcatggtga gctgaataag tacactgaaa gagggataag
    31381 aaagcaagct gggttgtaaa attcagcccc tgctttttga tatggaggta gtgaaatgtt
    31441 agttacgtat ccagctttat tttattatga cgacacagac ggaacagaag cgacttattt
    31501 tgtccatttc ccagattttg aatactcagc tacacaagga gaggggattt ctgaggcttt
    31561 ggctatgggg tcggagtggc tagggataac tgttgcagat ttgatagaga gtgatggaga
    31621 gttacctcag ccatcagata tcaatagctt gtctttaatt gataatgatc cttttaaaga
    31681 tgatgaagat ttcgtgtcaa cctatgacct tgataaatct tttatttcta tggtatctgt
    31741 tgatgtatca gaatacctag gaagtcagga acccattaaa aagactttga ctataccaaa
    31801 atgggcagat aagttgggac gagaaatggg acttaacttt tctcagactt tgacagacgc
    31861 tattgcagat aagaaagttc aagcctaaga ttaagcgtgg tatcgtggta atagtcaata
    31921 aaaaagcacg tccacttgtg ctagttactc gcctattgat tttatagatt tattagccct
    31981 ttcgagggct ttttatattg atttttatga gaaatgaaga aatcagactt ttaagaaaat
    32041 cactgatacc aagggtttaa atgaggtaat atggtataat taggacataa aataattttg
    32101 tggtaagatg gtagtatcta ttttagcata tttccgagca atcggggcga ttaaagagtc
    32161 gcatagaaag aggacaaaat ggcaacatac ggatttttag atgttttaga ggaagagttg
    32221 gacaagaact ttccctttga ctttgagatt agctgggaca aacgcaacca tgcggtagaa
    32281 gtgagttttc tattggaagc gcaaaatgct gcaggtgtgg agatggtgga tgaagacgga
    32341 gaggtttcat cagatgacat tctttttgag gaagcggtcc ttttctacaa tcctgccaag
    32401 tcaacagtca atgaggaaga ctatttgact gttattcctt acctgcctaa aaaaggattt
    32461 tcccgtgaat ttttagctta ttttgcgctt ttccttaaag atactgctga ggttgggcta
    32521 gatgtcctca tggacttttt ggaagaccca gaagcagagg aatttgtcat ggaatggaac
    32581 caagaagtct ttgaagaagg aaaaattggc ttggaagagg gagaatttta tccttatcca
    32641 aaatactagg agttggttgg aggtgttatg aagaaaattg ggacttattt ggtttatgtg
    32701 ctagctgttg tctttattat gctagctttt gcttgtggaa caatcgcatt tgcagagttg
    32761 gggtattccg cagttttagc ctttactttt ggttatgcct tcgctcttct aagcatgtat
    32821 ttaatcttta ttcttcatga gctgggtcat gctttttgtg gctacttgac aggctatcgg
    32881 ctggtggttt ttggattagg acattttatt ttgaccaaaa agtcaggcag gtttcatctt
    32941 agtagaacag ccattctgaa aaatgttggt gctcaataca ttggtttaaa agaggatgaa
    33001 agcgatcaaa gaatcatcct gatgctttca ggaggcttga tggttcatct cggcttgata
    33061 ttattggcga tattgtttgg atttttgaca agaagctggt attttgcagg gacttggatt
    33121 tttcttaatt tatctttctt cctaaataac attttgccag tcgacatcac tgatggagca
    33181 aaaatttggg aattactaca acaccctgaa aataccaaat acgcctacct ggtattgaga
    33241 cattctgccc agaccttgct agctcctcaa gaatatgatt tgaaagactt tgttcaagca
    33301 gttcctgagg atgcacgagg gagttttgcg gatggtgtat taggtatgca aggtgaagtt
    33361 tccattttgg aagggaagga agaagtagct aaacagcagt ttcaagcatt acttgagagg
    33421 acaactactc cgatgatgca gacagttgcc caactatccc tgcttcatat cgccttgttg
    33481 gaaggagatt ttgagcaagc ggagcaatat gctagtattc gacaggtcaa atcgtttctg
    33541 tctctcaaac tgtccaatct tcaagtgata caagcctggt atcaattaaa ggtgaagaaa
    33601 gatgtagatc gaactcgtaa ggctctcaag attgctagac agaaaatgga tagtagtcga
    33661 atgttgaggg acgagaaacg ctattatgaa aacttgttag cagagctgga aaaggaaatg
    33721 ttagaaggaa ctgaagatgg aactagaaat ttctgatttc caaggttgca agattgccct
    33781 cttttgtggg gataagctac tgacgatttt gcgtgatgac aaggacgata tcccttgtcc
    33841 caacatgtgg gagttgccag gtggtggaaa gagtgtcagg gaaaatctga tatagttttg
    33901 cattaaaaga atatcctttc aaggttattc ttttttaatt ttgtcccaaa ataattgact
    33961 ttgtcccgaa aatatagtat tatttgtata aggaggaatg aatcatgaaa aaatcagatg
    34021 ttcttgattt aataaagtat cattatgagg gcagagagac agaatttaga aatcaatcca
    34081 tagcaattgc tcggaacttc aataaacatg gtgatacaca aatagcacaa tatattatgg
    34141 ggttaatgtc tcaaagtgat agattcatgc cacaaataga aaatcctagt gagtatttga
    34201 ctcctgctaa actagatatt ggtcctctcc cattgcctct ttcaattatg aatgatttaa
    34261 aaggaataat aaacgctgtc aatcatcata ttggaataaa taaattttta tttgtgggat
    34321 ctccaggtac tggaaaaact gaaagtgtaa agcaggtggc tagacttatt ggcaaggaat
    34381 tacttgtagt agatttcagt cacttagtag atagtaagct agggcaaaca gtcaaaaact
    34441 tagcaactct ttttaatgaa atcaataatc ttcctttcaa gcaaaattat atcatcctat
    34501 ttgatgaaat tgattccata gtgttggata gggttaatca gaatgattta agagaaatgg
    34561 gacgagtgac ttctgccttt ttaaaggagt tggataggct gtcaccagaa attgtattaa
    34621 ttgcaacaac aaatcttttt gaaaatcttg ataaagcagt tacgagaaga ttcgatgcca
    34681 taattgactt tgaccgttat actgatgaag ataaagtaga agtagctact attattttaa
    34741 atgagttatt aaagcaattt aagaatgtag ctagagattt aaaattattt aaaaaaatta
    34801 tcaatagtgc caatgtaata ccgaatcctg gtgatttgag aaactcaata agaacgtcat
    34861 tggcatttag tgacccatca gatccgcatg attaccaaaa acgcctgcta agaagtttgc
    34921 ataatggtag aaatttatct atttctaaat tatcgaagct aggttttact gttagagaaa
    34981 ttgagatttt gacaggtatt tctaagagta gtgtatcacg agagttaagc gaggattaaa
    35041 atgaatacat tattgacatt acgaggtaaa agttttacac caaagtcagc aaaggggagg
    35101 ggaccgataa cgattcccgc agattctatt gttacgctaa accatttaaa tgaactttat
    35161 acatcccttg aacgagtaaa agaatattgg tctaataaca caatcattga tggagtactt
    35221 attagtgtgt attataatcg tgtcctagct aagagcaatc gtatcgatgg tttttttaat
    35281 gtgggtggcg gaaatgcaat tccaaatgaa acgattgtgg gtgcaaaatt tagtaatgat
    35341 aagagtaggc atattattac acactacatt tcaaaggaag tgttagataa gacaattgag
    35401 catactaaaa aagttataac aatattcaaa gattattttg ctagtgctcc catgacgagt
    35461 atggtgttct ccgactcttc aaaatttaat caaattgatt attctaagta tggtctgtcg
    35521 aaatcaaaat tcaaacaata cttaagagac gcttgctttg tcaaaggatt tggtattgaa
    35581 caggcagata tgtctactat acgtaattct attgtaacaa tctacgatgt aaaaactaat
    35641 ctcttaacat tacttaaaca acttgatatt gatgtttcag aagctaacat catggaccag
    35701 acaactgttt tacttgacga aaaaaatatt gagttactac tgctaaaagc accttatcta
    35761 gtatcaatga tagtagaaga tttttctagc ctgtcaccag agaattttta taatgatggg
    35821 aacacttttt ataataatct cccttttcca actaatgaac ctattattgg tgtcatcgat
    35881 acgttgtttg atgatggagt ttatttcaat gagtgggtag agtatcatga tttaatttca
    35941 ccagatatta gcaaaggaag tcaagactat aagcacggta cagcagtttc ctcggtaata
    36001 gtagatggag ctagtttgaa tccaaaacta gatgacggat gtggaagatt tagagtcaga
    36061 cattttggga tatctttaca gagtggtttc aattccttca caattatcaa acagattaga
    36121 gaaattgtgt ctcaaaatcc tgatattaag gtttggaacc tttcgcttgg atcaaatgat
    36181 gaaattaggg aaaactttat ttccgtcgag ggttcgttgt tagacgagat tcaatttgat
    36241 aacgatgtaa tttttattat tgcaggcact aatgggattg cccctgatgg acaacgaaaa
    36301 aagattggag caccagcaga ttcactcaat tcaattattg taaattctgt tgattttagc
    36361 aatcaagtcg tttcttattc acgcgaagga gttgtcctgt ctttctttat caaacctgat
    36421 gtttcatact atggcggggg gaacggagac ttcataaatg tttgtgaacc actagggctg
    36481 gctcgagtag ctgggaccag ttttgcggct ccatttattg ctagaaaaat ggcttacctc
    36541 attcatatta tgggattaag tcgtgaagaa gcaaaggctt tattaattga ttcagcgata
    36601 ccatggaatg ataaaaaaac attcgcagac atttctttac ttggatatgg ggttgtgcca
    36661 atcaaaatag aagatatttt gtctacacct gatgatgaaa ttaaatttat agtctcagat
    36721 gtttctagag catatgaaac ttataattat gatttcccag ttccaatttc taaagaacac
    36781 tatccatatg tagcaaaggc cactatgtgc tattttccaa agtgttctag aaatcaagga
    36841 gttgactata ctaatacgga aatgcaactt agtttgggag ttttagataa gaaaggcatt
    36901 aaaacaatta ataacgacaa tcaatattct gaaaatgcac caggatatgt gagagaaaag
    36961 tcggcacgaa atatttttag gaaatgggat aatgtcaaac atttaggaga aaaattttct
    37021 tctcgtaaaa aagctaagcc gattctgaat ccttctaatc ctcaatgggg aatgagtgta
    37081 aaaacaattg aacggttaag aaatgatgat ggttatggta ttcgttttgg agtagttgtt
    37141 actctaaagg agttgaatgg tgtcaataga atcgaagatt ttattcaaca agccgaatta
    37201 cgcggttggc tagttaatag attgcaagta gaagctcaag tagacctctt taatagttta
    37261 aatgaagaaa ttgaatttga atagtggata ttttatcctt attctagatc ttaggaacac
    37321 aagagggcaa agatatgaat attacttata tagttggaaa tggtttggat ttgcaatatg
    37381 gtttgaaaac aagatataaa gatttctatg aatttcaaaa taggacttac ataagtagga
    37441 aagagaacga ggaagaatat tcaaatctca tttatgagtc tctattttct gatacagtaa
    37501 atgattatga aaattggtca gattttgaat tgtcaattgg taaattaaca aaagataacg
    37561 acctcatctc ctcaagtata gaaataaagg agaaatttat agatgatttt agtgaagtag
    37621 ttgatgattt aagagaatat ctacgcatac aacaagaaaa aaatcttgag aaaggtaatg
    37681 caattgactt tataagcact ctagataata tgaggacctc tctccctgta attaatcaac
    37741 ctgctatcga taaaaaatat aatgaaaatc tatatcaaca cgatatcgtg aatatattaa
    37801 ctcttaatta cacaaatgta atcgataaat tatataatga gtcagcaaaa tcatttagca
    37861 atcaattacg aactaataat tataaatttc acattgcgcc tccaattcat gcacatggaa
    37921 cggtagatat ttgcacagtt ttaggagtta gtgacgagac acagatttca aatagttttg
    37981 atgaagaaca aaaagaatcc ttaataaaaa atttagtttt gaagaactat agagaaaata
    38041 tggatgttaa aaatagtgat attataaaaa attctgacat cattattctc tatggggttt
    38101 ctttgggaga aactgatagg tatatctgga gtcagattgc tgaacgatca atcagcggtt
    38161 ctgttcctgt cataatttac cactatgtac ctcattttga tccggggaat cccattagag
    38221 caaaacgcct atatagaaat gtagaagata aattcataca gaatagtggt atagacttag
    38281 agttagagaa aaaattaaga gacaacctta ttgtcgttat tggaaagact atttttaatc
    38341 tgatggaaag gtaagcaaaa tacataatgg aaacatggca agagttaaaa gttacagtga
    38401 agcgtgaggg agaggagttg gtttccaatc tcttgattga gctgggagcg caaggtgttg
    38461 cgattgaaga cagtatggac tatgtgggaa atgttgaccg ctttggcgag attttcccag
    38521 aggtggagca acaggaagaa atcgtagtga ccgcctacta ccctgaaacg gttgatgtag
    38581 cagcagttga agcggatttg caggatcgtc tggcagaatt gaccgacttt atggacctag
    38641 gagaagtcaa gatgggcacg actgccttgg ctgaggaaga ctgggctgac aactggaaga
    38701 agtattatga accggcacgc atcacccatg acctgaccat cgtaccgtca tggacggact
    38761 atgaggcaac agcaggagaa aagattatca agctggatcc tggtatggcc tttgggacag
    38821 ggacccaccc aacaaccaag atgagcctct ttgccttgga acaggttctt cgtggtggcg
    38881 aaacagtgct agatgtaggg actggttcag gggttctttc tattgcaagc tcactcctag
    38941 atgccaagga gattttcgcc tatgacttgg atgatgtggc ggttcgtgtc gctcaggaaa
    39001 atattgagct caacactggt atggaaaata tccatgtagc agcaggagac ttgcttaagg
    39061 gagttgagat tgaagcagat gtcatcgtgg ctaatatctt ggcggatatt ctcattcatc
    39121 tgacggagga tgcttatcgc ttggtaaagg atgaaggcta cctcatcatg agtggcatta
    39181 tcaaggacaa gtgggacatg gtgcgccagt cggctgagtc agctggattt ttcctcgaaa
    39241 ctcacatggt tcaaggggaa tggaatacct gtgtctttaa gaaaaccaag gatatctctg
    39301 gtgtgattgg aggctagcat gcagcagtat tttgtaaaag gcagtgctat ctctcctgtc
    39361 actatcgagg acaaggaaac cagtaagcat atgtttcagg ttatgcgctt gaaagaagag
    39421 gatgaggtta ccttagtctt tgatgatggc atcaagcgct tggcgcgcgt gctggatatg
    39481 gaaaatcgtc agtttgagtt ggtccaagaa ttaaatgata atgtggaact accagtccaa
    39541 gtgaccatcg catctggatt tcccaaggga gacaagctgg agttcatcgc tcaaaaagta
    39601 accgaactgg gtgctagcca aatctgggcc tttcctgcag actggtcagt tgccaagtgg
    39661 gatggcaaga aattgggtaa aaaagttgaa aaactagaaa aaattgccct tggagcagcc
    39721 gagcaaagca agcgtaatat tgtaccaagt attaaacttt tcgagaaaaa agcagatttt
    39781 ctagctcagc tggaccagtt tgactttatc atagtagcct atgaagaatc agctaaagaa
    39841 ggagaagccg ctgcgcttct gcaagcagtc actggtcttg aaacaggagc caaactgctc
    39901 tttatctttg gtccagaagg cggtctctca cctgcagaaa tcgaaagttt tgaagctaag
    39961 ggagccgttt tggtaggcct aggtcctcgt attttgcgag cagaaacagc accgctttac
    40021 gccttatcag cccttagtgt tttagtagaa ttagagaaat aagaggaaga aaatggaaca
    40081 aaaacaccgt tcagaatttc cagagaagga actctgggac ttaacagccc tataccaaga
    40141 ccgtgaggat ttcttgcgtg caatcgagaa agctcgtgaa gacatcaacc agtttagccg
    40201 tgattacaag ggcaatcttc acacttttga ggatttcgag aaggcctttg cggaattaga
    40261 acagatctac attcagatga gccatattgg caactatgct tttatgcctc agacgacgga
    40321 ctatagcaat gacgaatttg ccaatattgc ccaagctggg atggaatttg aaacagatgc
    40381 cagcgtagcc ttgaccttct ttgacgatgc cttggtggta gcagacgagg aagtcttgga
    40441 ccgtttgggt gaattgcctc acttgacggc agctattcgt caggccaaaa tcaaaaaagc
    40501 ccactatcta ggggctgatg tggagaaggc cttgaccaat ctcggtgaag ttttctatag
    40561 tccgcaggac atttatacta agatgcgagc tggggatttt gaaatggctg actttgaagc
    40621 ccatggcaag acctataaaa acagctttgt cacctatgag aatttctacc aaaatcacga
    40681 ggatgctgag gttcgtgaga aatccttccg ttccttctca gagggacttc gtaagcacca
    40741 aaatacggct gcagcagcct atctggctca ggtcaagtct gaaaaactct tggctgatat
    40801 gaagggatac gactctgtat ttgattatct tctagctgaa caagaagtgg accgtgtcat
    40861 gtttgaccgc cagattgacc tcatcatgaa ggactttgca ccagtcgctc agagatacct
    40921 caagcatgtt gccaaggtaa atggtcttga aaagatgacc tttgcagact ggaaattgga
    40981 cttggacagc gccctgaatc ctgaagtgac tattgacgat gcctatgatt tggtcatgaa
    41041 gtcggtagaa cctttggggc aagaatattg tcaggaagtt gctcgttacc aagaagagcg
    41101 ctgggtggac tttgctgcta acagtggcaa ggattccggt ggttatgcgg cggacccata
    41161 tcgcgtacac ccttatgtac tcatgagctg gacaggccgt ttgagcgatg tctatacctt
    41221 gattcatgaa atcgggcatt ctggtcaatt catcttttca gacaatcacc aaagctattt
    41281 caacgcccac atgtcgacct attatgttga agcaccgtca accttcaatg aattgctact
    41341 cagtgattac ttagagaacc agtctaatga cccacgtcaa aaacgcttcg ctctggctca
    41401 tcgcttgaca gacacctact tccataattt catcacccac ctcttggaag ccgccttcca
    41461 gcgtaaggtg tatacattga ttgaagaagg ggagaccttt ggagcaagca agctcaacag
    41521 cattatgaag gaagttttga cagatttttg gggcgatgcc attgaaatcg acgacgatgc
    41581 agctttgact tggatgcgcc aagctcacta ctatatgggc ttgtatagtt acacttactc
    41641 tgctggtctt gtcatctcga cagctggtta ccttcatctt aaaaactcag aaactggagc
    41701 tgaagactgg ctcaatctcc tcaaatcagg tggtagcaag acaccacttg agtcagccat
    41761 gattatcggt gctgatattt caacagacaa accactccgt gataccatcc aattcttgtc
    41821 tgacacagtt gaccagatta tcgcctacag tgctgagttg ggggagtaag gggaatagaa
    41881 aaattttcta gaatgatgtt tatgggcttg ttaagcgtca ttctatttgt cttagttgta
    41941 gctattttca aaaatgtcgt tgaaggtcgt gatgttaaat ttgaacttac tgtagaactg
    42001 gtattgatag ttatttacgt cattttatat cagattgtat ttaattgaga attcaatatt
    42061 gagtcattta agactgcctt tttgaacagt tgctagaaat gtagaggtat tgaccatgta
    42121 tcaagattta ctaagaaaaa tagcagaaga aaaaccaaat tataaccagg aagaaatcca
    42181 gtggttgttt gatcatttgg gaaatccttc tccagaaatt cgtgatgacc tttcaaatca
    42241 aggcttgcac tatctttcaa aagaaaagga tacaacaggt ttctcaagtc agtatggttg
    42301 ggttcattct tttgcacatg gagccgattt actgacagag gtggtctgtc atccagactt
    42361 tcctataaac agaattcatg aagtatttga tatacttggc caactattta aaagaatgtc
    42421 gattctcttt acagatgatg aggattggcg tttagcaaga gtgatctatg aacctatttt
    42481 acaagggaag ttggagcaag aacaagtagc ttcttggata aaaactgttg attttccgat
    42541 agaagaaagg gaggattttt acaaattttc caactttaga tcctgtctgg tggaagtcta
    42601 tgtccaactt gaccagagaa atagtttaca agatgacctg aaagaagcta tccagtcttt
    42661 tcaatactag ggattagcta atagttctat gattttcaaa aaatttccaa tcaattttct
    42721 tgaaaccctt tcctactttt gatagactag tatctagttt ttgaaaaaag gagaaagaaa
    42781 atgaaaaaat ttgttgctga gttaatcggt acgttcatgc ttgtgttcgt tgggacagga
    42841 gctgttgttt ttggaaatgg tcttgatggc cttggtcacc ttggaatcgc ctttgccttt
    42901 ggtttggcaa tcgtggtggc agcctactca atcggaactg tttcaggtgc tcacttgaac
    42961 ccggctgttt cgattgctat gtttgcaaac aaacgtttgt catcttcaga acttgtaaac
    43021 tacatccttg gtcaggttgt tggagctttc atcgcttctg gcgcagtctt cttcctcttg
    43081 ggtaattcag gtatgtcaac tgctagtctt ggtgaaaatg ccttggcaaa cggtgtcact
    43141 gtctttggtg gtttcttgtt tgaagtcatc gcaactttct tgtttgtctt gactatcatg
    43201 actgtgactt cagaaagtaa gggcaatggc gcgattgctg gtttggtaat cggtttgtca
    43261 ttgatggcga tgattcttgt cggactgaag attactggac tttcagtaaa cccagctcgt
    43321 agcttggcac cagctgtctt ggtaggcggc gcagcccttc aacaagtttg gattttcatc
    43381 cttgcaccaa tcgctggtgg agttcttgca gcccttgttg caaaaaattt ccttggaaca
    43441 gaagaataat tgaaactcaa aaagccttgc tcctcatctt gaggaacagg gctttttcgt
    43501 atgatactct tcgaaaatct cttcaaacca cgtcagcttc accttgccgt aggtatggtt
    43561 actgacttcg tcagtttcat ctacaacctc aaaacagtgt tttaagctga cttcgtcagt
    43621 tctatctgca acctcaaaac agtgtttt
//
LOCUS       DAVLZS010000015        40370 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLZS010000015 DAVLZS010000000
VERSION     DAVLZS010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40370
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.015"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(284..751)
                     /locus_tag="VYO88_000825"
     CDS             complement(284..751)
                     /locus_tag="VYO88_000825"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1718959.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEISLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(752..1957)
                     /locus_tag="VYO88_000826"
     CDS             complement(752..1957)
                     /locus_tag="VYO88_000826"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1718960.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(1977..2612)
                     /gene="ribE"
                     /locus_tag="VYO88_000827"
     CDS             complement(1977..2612)
                     /gene="ribE"
                     /locus_tag="VYO88_000827"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1718961.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVTKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(2597..3697)
                     /gene="ribD"
                     /locus_tag="VYO88_000828"
     CDS             complement(2597..3697)
                     /gene="ribD"
                     /locus_tag="VYO88_000828"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1718962.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(3831..3945)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            4102..4695
                     /gene="ruvA"
                     /locus_tag="VYO88_000829"
     CDS             4102..4695
                     /gene="ruvA"
                     /locus_tag="VYO88_000829"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1718963.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            4705..5268
                     /locus_tag="VYO88_000830"
     CDS             4705..5268
                     /locus_tag="VYO88_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1718964.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWAQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            5265..5942
                     /locus_tag="VYO88_000831"
     CDS             5265..5942
                     /locus_tag="VYO88_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1718965.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(6079..7110)
                     /locus_tag="VYO88_000832"
     CDS             complement(6079..7110)
                     /locus_tag="VYO88_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV1718966.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGRDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(7365..8048)
                     /locus_tag="VYO88_000833"
     CDS             complement(7365..8048)
                     /locus_tag="VYO88_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1718967.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGVALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(8060..9004)
                     /locus_tag="VYO88_000834"
     CDS             complement(8060..9004)
                     /locus_tag="VYO88_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1718968.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            9136..11967
                     /gene="uvrA"
                     /locus_tag="VYO88_000835"
     CDS             9136..11967
                     /gene="uvrA"
                     /locus_tag="VYO88_000835"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1718969.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            11960..13021
                     /locus_tag="VYO88_000836"
     CDS             11960..13021
                     /locus_tag="VYO88_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1718970.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMDLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            13153..13551
                     /gene="spx"
                     /locus_tag="VYO88_000837"
     CDS             13153..13551
                     /gene="spx"
                     /locus_tag="VYO88_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1718971.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            13617..14186
                     /locus_tag="VYO88_000838"
     CDS             13617..14186
                     /locus_tag="VYO88_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1718972.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            14273..14539
                     /locus_tag="VYO88_000839"
     CDS             14273..14539
                     /locus_tag="VYO88_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1718973.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            14543..14962
                     /gene="ruvX"
                     /locus_tag="VYO88_000840"
     CDS             14543..14962
                     /gene="ruvX"
                     /locus_tag="VYO88_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1718974.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            14978..15283
                     /locus_tag="VYO88_000841"
     CDS             14978..15283
                     /locus_tag="VYO88_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1718975.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            15591..16841
                     /locus_tag="VYO88_000842"
     CDS             15591..16841
                     /locus_tag="VYO88_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1718976.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKTGKKAVIAKLPPEARLICQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            16838..17395
                     /locus_tag="VYO88_000843"
     CDS             16838..17395
                     /locus_tag="VYO88_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1718977.1"
                     /translation="MTPLFELVILGKLLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            17541..19073
                     /gene="cls"
                     /locus_tag="VYO88_000844"
     CDS             17541..19073
                     /gene="cls"
                     /locus_tag="VYO88_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1718978.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTLSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            19331..20869
                     /locus_tag="VYO88_000845"
     CDS             19331..20869
                     /locus_tag="VYO88_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1718979.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQTKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDTIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            20989..23196
                     /gene="nrdD"
                     /locus_tag="VYO88_000846"
     CDS             20989..23196
                     /gene="nrdD"
                     /locus_tag="VYO88_000846"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1718980.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLDDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            23208..23348
                     /locus_tag="VYO88_000847"
     CDS             23208..23348
                     /locus_tag="VYO88_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1718981.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGVGKKERLLSFREQFLNKNK
                     KK"
     gene            23441..23899
                     /locus_tag="VYO88_000848"
     CDS             23441..23899
                     /locus_tag="VYO88_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1718982.1"
                     /translation="MMTEFEKSQSAHDGGFWDTENFVYEEWLETNIQKEMGINLPENR
                     VPSIQFVLFGESGCALRFLNLRLRLNERLLNYAGHIGYSIRPSERGKGYAKETLRQGL
                     QVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVERYWIEVANE"
     gene            23892..24482
                     /gene="nrdG"
                     /locus_tag="VYO88_000849"
     CDS             23892..24482
                     /gene="nrdG"
                     /locus_tag="VYO88_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1718983.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            24490..25107
                     /locus_tag="VYO88_000850"
     CDS             24490..25107
                     /locus_tag="VYO88_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV1718984.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            25373..25681
                     /gene="rpsJ"
                     /locus_tag="VYO88_000851"
     CDS             25373..25681
                     /gene="rpsJ"
                     /locus_tag="VYO88_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1718985.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            25898..26524
                     /gene="rplC"
                     /locus_tag="VYO88_000852"
     CDS             25898..26524
                     /gene="rplC"
                     /locus_tag="VYO88_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1718986.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            26549..27172
                     /gene="rplD"
                     /locus_tag="VYO88_000853"
     CDS             26549..27172
                     /gene="rplD"
                     /locus_tag="VYO88_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1718987.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVIVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            27172..27468
                     /locus_tag="VYO88_000854"
     CDS             27172..27468
                     /locus_tag="VYO88_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1718988.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            27486..28319
                     /gene="rplB"
                     /locus_tag="VYO88_000855"
     CDS             27486..28319
                     /gene="rplB"
                     /locus_tag="VYO88_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1718989.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            28423..28704
                     /gene="rpsS"
                     /locus_tag="VYO88_000856"
     CDS             28423..28704
                     /gene="rpsS"
                     /locus_tag="VYO88_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1718990.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            28716..29060
                     /gene="rplV"
                     /locus_tag="VYO88_000857"
     CDS             28716..29060
                     /gene="rplV"
                     /locus_tag="VYO88_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1718991.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            29073..29726
                     /gene="rpsC"
                     /locus_tag="VYO88_000858"
     CDS             29073..29726
                     /gene="rpsC"
                     /locus_tag="VYO88_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1718992.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDVLRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            29730..30143
                     /gene="rplP"
                     /locus_tag="VYO88_000859"
     CDS             29730..30143
                     /gene="rplP"
                     /locus_tag="VYO88_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1718993.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            30153..30359
                     /locus_tag="VYO88_000860"
     CDS             30153..30359
                     /locus_tag="VYO88_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1718994.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            30384..30644
                     /gene="rpsQ"
                     /locus_tag="VYO88_000861"
     CDS             30384..30644
                     /gene="rpsQ"
                     /locus_tag="VYO88_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1718995.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            30670..31038
                     /gene="rplN"
                     /locus_tag="VYO88_000862"
     CDS             30670..31038
                     /gene="rplN"
                     /locus_tag="VYO88_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1718996.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            31116..31421
                     /gene="rplX"
                     /locus_tag="VYO88_000863"
     CDS             31116..31421
                     /gene="rplX"
                     /locus_tag="VYO88_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1718997.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            31445..31987
                     /gene="rplE"
                     /locus_tag="VYO88_000864"
     CDS             31445..31987
                     /gene="rplE"
                     /locus_tag="VYO88_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1718998.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            32005..32274
                     /gene="rpsN"
                     /locus_tag="VYO88_000865"
     CDS             32005..32274
                     /gene="rpsN"
                     /locus_tag="VYO88_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1718999.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            32559..32957
                     /gene="rpsH"
                     /locus_tag="VYO88_000866"
     CDS             32559..32957
                     /gene="rpsH"
                     /locus_tag="VYO88_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1719000.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGSNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            33149..33685
                     /gene="rplF"
                     /locus_tag="VYO88_000867"
     CDS             33149..33685
                     /gene="rplF"
                     /locus_tag="VYO88_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1719001.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            33769..34125
                     /gene="rplR"
                     /locus_tag="VYO88_000868"
     CDS             33769..34125
                     /gene="rplR"
                     /locus_tag="VYO88_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1719002.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            34143..34637
                     /gene="rpsE"
                     /locus_tag="VYO88_000869"
     CDS             34143..34637
                     /gene="rpsE"
                     /locus_tag="VYO88_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1719003.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            34609..34833
                     /gene="rpmD"
                     /locus_tag="VYO88_000870"
     CDS             34609..34833
                     /gene="rpmD"
                     /locus_tag="VYO88_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1719004.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            34978..35418
                     /gene="rplO"
                     /locus_tag="VYO88_000871"
     CDS             34978..35418
                     /gene="rplO"
                     /locus_tag="VYO88_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1719005.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            35431..36741
                     /gene="secY"
                     /locus_tag="VYO88_000872"
     CDS             35431..36741
                     /gene="secY"
                     /locus_tag="VYO88_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1719006.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            36892..37530
                     /locus_tag="VYO88_000873"
     CDS             36892..37530
                     /locus_tag="VYO88_000873"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1719007.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            37647..37865
                     /gene="infA"
                     /locus_tag="VYO88_000874"
     CDS             37647..37865
                     /gene="infA"
                     /locus_tag="VYO88_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1719008.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            37890..38006
                     /gene="rpmJ"
                     /locus_tag="VYO88_000875"
     CDS             37890..38006
                     /gene="rpmJ"
                     /locus_tag="VYO88_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1719009.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            38024..38389
                     /gene="rpsM"
                     /locus_tag="VYO88_000876"
     CDS             38024..38389
                     /gene="rpsM"
                     /locus_tag="VYO88_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1719010.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            38407..38790
                     /gene="rpsK"
                     /locus_tag="VYO88_000877"
     CDS             38407..38790
                     /gene="rpsK"
                     /locus_tag="VYO88_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1719011.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            38833..39768
                     /locus_tag="VYO88_000878"
     CDS             38833..39768
                     /locus_tag="VYO88_000878"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1719012.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            39780..40166
                     /gene="rplQ"
                     /locus_tag="VYO88_000879"
     CDS             39780..40166
                     /gene="rplQ"
                     /locus_tag="VYO88_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1719013.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
BASE COUNT        12274 a         7687 c         8753 g        11656 t
ORIGIN      
        1 acgcataaaa tcaggtgttc aaaaaccttg attttatgcg ttttatcata gaaatattta
       61 tttcattttt tcctaattct tttcgaaact ctttttaaac gacgtcagtt ttatcagtaa
      121 tctcaaaaca gtgttttgag ctaattttgc cagttttgtc tgtaacatcg aagttgtgtt
      181 ttaccactct gcgactggtt tcctagtttg ctctatgatt ttcacagagt attaaattgc
      241 gattttgcca agtttcttta ttcgtctaaa agtagagtct gttctatgcg tctaatgtac
      301 gaattaggtt gaccatttca atagctcctt gtgcacactc agaaccctta tttcctgctt
      361 tagtaccagc tcgttctatg gcttgttcaa ttgtatctgt cgttagcaca ccaaacataa
      421 caggaatttc gctatttaaa ctgatttggg cgattccctt agatacctcg ctacatacat
      481 aatcataatg acttgtattc cctctaatga cagctcccaa gcagataatt gcatcatatt
      541 ttttactttt tgccattttt gatgcaatca gtgatatttc aaaagctcct ggaacccagg
      601 ctacctctat atctttctcg tttacattct ctcttttgag attatctagt gctccagata
      661 ataattttga agttataaat tcattaaatc tcgctacaac aatacctatt ttaatattgt
      721 ttgctactaa attaccttca taagtgttca tttatttttc ctccatattt aaaatgtgac
      781 ccattcgatt tttctttgtt tctaaataaa aactatcgta aggattggct tctatttcga
      841 ttgatattct actggaaatg gtaattccat atttttctaa ctgttcaacc ttgtcaggat
      901 tatttgtcag taaatgaagt gactgaagtc ccagatcttt aagcatttgt gctccaatat
      961 gatattctct taaatcacct tcaaagccta atgcaagatt ggcatcaagc gtatccatgc
     1021 cttgatcttg taaatgatag gcttttaatt tattgataag tccaattcct cgtccctcct
     1081 gtcgcaagta aagtaagaca cccgaaccat tctcaacaat cattttcata gctttatcga
     1141 attgctgtcc acaatcgcaa cgtaaggagc ctaaaacatc ccctgttaaa cattcggagt
     1201 ggacccgaca taatacattg gcttcatcct ctatgtttcc cataataaga gcaagatgat
     1261 gttccccatt tagtttatct atatagctaa ttgctttgaa attaccgtat ctagtaggca
     1321 tattgacagt tgaaactcgt tctaccagct gatcatatac ttttctatat tcttgtaatt
     1381 ctttgatggt aattagtgga atgttgtgtt tcttcgagaa ctgaattaaa tcatctgttc
     1441 tcatcatttt gccatcatga ttcattattt cacaacatag gccacactct tttagtccag
     1501 ctaattttaa taaatcaaca gttgcttctg tgtgtccact tctttctaga acaccacctt
     1561 tttttgcaat taaaggaaac atgtgtcctg gcctgcgaaa atcagagggt gttatatctt
     1621 cagctacaca catacgtgcg gtcagtcctc tttcctcggc agaaatacct gtggtcgttt
     1681 ctttataatc aattgaaact gtaaaagcag tcttatgatt atctgtattg ttttcaacca
     1741 taggtgaaag cattaattga ttagctaaac tttcgctcat aggcatacaa attaatcctt
     1801 tggcataagt agccataaaa ttaacatttt ctgttgtagc tgcttgtgca gaacaaatta
     1861 agtctccttc attttctcta tccttgtcgt ctataacaag aacaagtcgt cccttctgca
     1921 atgcttctaa tgcttcttgt atttttcgat attccattga ctgattatcc tttctgctaa
     1981 aatccatttt gatataatag ttccttagat atttctgatt ttggagagtt atccatcagt
     2041 ttttgcacat atttacctaa gatatcattt tcaagattta ctgtactccc gacttgttta
     2101 ctcttaagaa tggtttgttc caaggtatga gggataacag atactgaaaa gtttactttg
     2161 gagactttag tgacagtcag actaatgccg tcaattgtaa tagatccttt ttcaactatt
     2221 aaatctaaaa tttctttttg tgtgttgatt tgataccata cagcattatc atcttttttt
     2281 attgacgaga tttttcctgt accatcaatg tgtcctgtaa cgacgtgacc cccaagtcga
     2341 ccgttgacag ataaggctct ttctagattc acctcacttc catgttttaa tagagtaaga
     2401 gctgttcgac tccatgtttc attcattaca tcaactgtaa aggattgatg attgaaatga
     2461 gtaactgtaa gacagatacc atttactgct atactatcgc ctaaatggat atccgttaat
     2521 atttttgagg ctttaattga tagtttacaa ttacgagagt ctttctgtat tctttcaact
     2581 tttccgattt cttcaattat tcctgtgaac atggataaat cacttcactt tctatgagat
     2641 agtcatttcc tatttgagaa aatgcataag gtttcaatct aatagcgtca tttggcaaag
     2701 aaataccttc acctccgaca ggaaacttgg cactacctcc aaaaattttt ggtgcaatat
     2761 atattttcag ctcatcaaca atttgttgtt ccaaagcact ccaattcatt agactgcccc
     2821 cttctagaac taggctatca atctgcatgt ttcctagatg ttgcattaaa ctcgataagt
     2881 ctatatgatt gccttttttc tttatggaaa gtatttcaca gccatgattt tgatatagct
     2941 tcattttatt tttgtcttca gaggaagtgg caatgtaagt tttaatatca tttgctgttt
     3001 ttacgatttt agaggtaaga ggagttcgta aatgtgtatc gcatatgata cggataggat
     3061 ttttcccttc ctccaatcta catgtcagca aaggatcgtc ttgaataaca gtattgactc
     3121 ccaccataat tgcactaaca tggtgtcgta actgatgcac atgctttctt gcttcttctt
     3181 cagtaatcca tttggattga tttgttttag tggctatttt tccatccatt gacattgcat
     3241 atttcataaa aacatagggt acatgctggg taatatactt tctaaaactt tttattaagt
     3301 taagacactc attttctaaa attccaacag taacttgaag attattttcc tcaagtatct
     3361 ttactccttt tccagataca ataggattac agtctaggct tccaatgact actcttgtaa
     3421 taccactatc gattatagca tctatacagg gaggtgtttt cccgaagtga caacagggtt
     3481 caagtgttac ataaagcgtc gctccgacag gggattctct acagttttta agagcatttc
     3541 tctcagcatg tgggccacca aaaaactcat gataaccttg tccgataatg tgattatctt
     3601 ttacaataac tgcgccgacc ataggattgg gattgacgta accagcccct ttttgtgcca
     3661 gttttattgc taatttcata tattttgaat cgctcatctc gctacctcca aaaaaatata
     3721 ccttgaatag gggactactc aaggcataca aaagaaaact tatgcgatta acaaaaatgc
     3781 tctgaaatga caagtaatca tttcagagca cgcaaaaagc acaaatatac ttttatcttc
     3841 tttcatccag actatactgt cggctttgga atttcaccaa atcatgcctt tcggctcgtg
     3901 ggctatacca ccggtaggga atttcaccct gccctgaaga tagttattca attacagatg
     3961 attatagtac ttaattttga atatgtcaac agataaatac cgattgtttt tgatatactg
     4021 tatttgtgat aatcgattct cgctcctcgg ataaagaaaa tatgatatac tagataaacg
     4081 aaataagaga gaaggaatac tatgtacgca tatttaaaag gaatcattac caaaattact
     4141 gccaaataca ttgttcttga aaccaatggt attggttata tcctgcatgt ggccaatcct
     4201 tatgcctatt caggtcaggt taatcaggag gctcagattt atgtgcatca ggttgtgcgt
     4261 gaggacgccc atttgcttta tggatttcgc tcagaggatg agaaaaagct ctttcttagt
     4321 ctgatttcgg tctctgggat tggtcctgta tcagctcttg ctattatcgc tgctgatgac
     4381 aatgctggct tggttcaagc cattgaaacc aagaacatca cctacttgac caagttccct
     4441 aaaattggca agaaaacagc ccagcagatg gtgctggact tggaaggcaa ggtagtagtt
     4501 gcaggagatg gccttcctgc caaggtcgca gtgcaagcaa gtgctgaaaa ccaagaattg
     4561 gaagaagcta tggaagccat gttggctctg ggctacaagg caacagagct caagaaaatc
     4621 aagaaattct ttgaaggaac gacagataca gctgagaact atatcaagtc ggcccttaaa
     4681 atgttggtca aataggagca gagaatgaca aaacgttgtt cgtgggtcaa gatgaccaac
     4741 ccactctaca tcgcctatca tgatgaggag tgggcccagc ccctccatga tgaccaagcg
     4801 ttgtttgagt tgttgtgtat ggaaacctat caggcaggcc tgtcttggga aacggtactc
     4861 aacaaacgcc aagctttccg agaagccttt catagctatc aaattcactc agtcgcagag
     4921 atgactgaca ctgaattgga agccatgctg gagaatccag ctatcattcg aaatagagcc
     4981 aagatttttg ctacacgcgc taacgcccaa gcctttctac agttacaggc agagtacggc
     5041 tcttttgatg cctatctttg gtcttttgtt gaggggaaaa ctgtcgttaa cgatgttcct
     5101 gattatcgcc aagccccagc taaaacaccc ttatctgaga aattagccaa agatctcaaa
     5161 aaacgaggct tcaagttcac aggcccagtc gccgtattgt cttttctaca ggctgcaggg
     5221 ctagttgatg accacgagaa tgattgtgag tggaaaggtc ttaaatgatg tctaacaaaa
     5281 ataagggaat tctgattttt gcgattctct atacagtcct ctttgtgttt gatggcgtta
     5341 aattgctggc ttctttaatg ccatctgcca ttgcaaatta tcttgtttat gtagttttag
     5401 ctttatatgg ctccttcttg ttcaaggata gattgatcca acaatggaag gagattagaa
     5461 agactaaaag aaaattcttc tttggagtct taacaggatg gctctttctc attctgatga
     5521 ctgttgtctt tgaatttgta tcagagatgt tgaagcagtt tgtgggacta gatggacaag
     5581 gtctaaatca gtctaatatt caaagtacct ttcaagaaca accactactg atagctgttt
     5641 ttgcttgtgt cattggacct ctggtagaag aattattttt ccgtcaggtc ttattgcatt
     5701 acttgcagga acggttgcca ggtttactaa gcattattct ggtaggactt gtttttgctc
     5761 tgactcatat gcacagtttg gctctatcag agtggattgg tgcagttggt tacttaggtg
     5821 gaggccttgc cttttctatt atttatgtga aagaaaaaga gaatatctac tatcccctac
     5881 ttgttcacat gttaagcaac agcctctcct taatcatttt agctatcagt atagtaaaat
     5941 gaaatgagaa caggacaaat cgatttctaa caatgtttta gaagtagagg tgtactattc
     6001 tagtttcaat atactgtaat atgtgatgaa aatgccagta atgataccga gaaaaaagct
     6061 gagaaacttt tcccagcttt atttgttata gtcaaagaga atgacttgtt cctgtgcatc
     6121 tacatgagca tggaccccaa agggtacaat tgctcttgga gttgcgtggc cgacattcag
     6181 attatagaca atcgggatat tgctgtcaat gatatccaat agtgcctctt tatagtcgtc
     6241 atggaaagtt tcatccatag gttttccgac caagagtcca ttgatgaccg cgaatatgcc
     6301 agtgtccttt aaagttagca acatcttttt gaagtcttct ggcttaggct tttcttcgct
     6361 tgtttcgagc aagaggattt tcccttccca gtctgacaag tcagggaaaa gtttgtattt
     6421 ttggcagagt tccgtgctat ctgcgtatcg agagttgtca aagatatcgt agagggattc
     6481 gaggcaacca ccgaggattt tcccctcgaa ctgggcactt ccttgcaaca agtcaaaacc
     6541 tgtatttgta tgactgacac gaggtgttcc cagggccgtg ggactaaaat cagttcgttc
     6601 ctcataccaa acgtcactag ggcggatttc tgaaattctt cccgtctcaa tcaattcttt
     6661 aaagtagtga aggctatagg ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa
     6721 ggattgacca taaaaagtct tgattcctaa tttatgcaac atgaggtggt tcatggttgt
     6781 atccgagaag ccaagaaaaa ttttttgttt gataaccttt tggagttggt cattttcaaa
     6841 aagataaggt agcaagcgat aggtatcgtc tctaccgatg gcacatagga tcatgtcgat
     6901 gctatcatca gaaaaggcat gaatcaaatc ctctgcacga gcttcaggat ggtccttgat
     6961 aaagtctaat ccttttaacg aatggggcaa aaagatggga ttgagtccca gatccttgag
     7021 acgttggata cccaagtcca cttcgtgttt gacaaaatcc tctccgataa tgccactaga
     7081 taaactaaca ataccaatag tagaaaccat atctcatcct cctagaaata gattgagcct
     7141 attttatcac aaaatataag agaaagctat gtgggatttc agaagaatac ttttaatact
     7201 cttcgaaaat ctcttcaaac cacgtcagtt ttatttgcaa cctcaaagct gtgctttgag
     7261 caacctgcag ctagcttcct agtttgctct ttgattttca ttgagtataa ctcaaaaaag
     7321 taagtgaaaa agcaaccgca cctgcagttg cttttatcgt tttcttattc ttgatagcgt
     7381 gttggtcctg cacttgcact acggatattc aagcgtttct tgagatagaa gcgaagggct
     7441 aggagggcta ctccaataat agctagtggc aatggatcca gtactgggtt aaggctagct
     7501 ggtaggaagc ttgttgcaaa gaagacaagc aaccaaagga acatagaagc taggataact
     7561 agtacagatt tccagaaagg tggacgttga ctgcgatcca tatctggtcc atagtattgg
     7621 taaacaaagt agtacatcaa gtagaaggca aatccaccaa ccagtccaac taatagaaga
     7681 gtaatcaatc catagccgaa agcttgatct gccgcaaaga aggttgtgag ggcgctgaca
     7741 agggcaaaga ggctagtgat gaaaagagct gagtccataa tcatcagttt tgggtcatca
     7801 ttttcttttg gatgctcttt ttcgtactgc tctttgacag tgaagctatg agcccaatga
     7861 gttggtgcgc cgtataggga acgggcagtt gtacctttag attgctcctc aaggatttgg
     7921 ggaatgactt cctcaaaaat agtctggatt tcagcgtctg ttttcccatc tttgatgaat
     7981 tgttgggtag caatgtggac aaactcttgg tttttcttag ttaatttttg tagatcaatt
     8041 tgagacatag gaactcctct tagaaccatt ttttatggat gagatagaga gtgagcgaga
     8101 cactcatagc aaaggcgata aagacgatta accagaaggc atttggctct ccgtttaggg
     8161 gaatttcatt atccttaaag ttcatcccgt aggcagaaaa gaccatggtt gggatggaca
     8221 tgacgatggt cacaagggcc aaggttttca tgatgttgtt ctggttgtta gaaatgatag
     8281 aggcaaaggt ctctgtcata gaatgcaaga cgtttccata aatatctgcc atctcgatgg
     8341 cctgttgggt ttcaatcagg gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga
     8401 tattgctggt tgaactggtc aatttcttaa tcacgcgctc atttgttttg agggaggcct
     8461 tgaaatagac gatagttttt tccaattcca tgagctcaat caattcttca ttacgagttg
     8521 attgatgcag ttgactttcg atttgttcac tcttgcggtc gattgaacga agggctgtta
     8581 ggtaaagctc tgcattgcga taaagaattt gaaagataaa acgtgaacgc atgaaggtat
     8641 agaaattacg caatcgacgg ttgataaaga catcaaggac aggtagtggt tccaaacacg
     8701 tagtgataat ggtttcctca gtgatgataa taccaagcgg gatggttacg tagtaggtgc
     8761 ggttatttct ttcctccgtg accggcacgt ctacgataat cagggtatac tcgtcttcaa
     8821 tggtaatacg agacatttct tccgcatcga gcggtgctcg aaggtcggca atatcaatat
     8881 cgaaggtgtt ggcgatttcg agtgattcat tttgagtcgg attgacgaga ttgatccaag
     8941 tacccggttc aagcgtatcg atctctttaa attcagttgt tgtagagaga aaaacttgtt
     9001 tcatatccct tatcctttct catttttcag attttttcac actgtactat tatactacaa
     9061 aatcggcctt ttgggtaata gaatctcact ttttttggta taatggtaag caataatgga
     9121 ctagaaagaa caaagatgca agataaaatt gtcattcatg gggcgcgtgc ccataattta
     9181 aaaaatattg atgtggagat tccgcgagac aagttggttg tcgtgactgg cttgtcaggt
     9241 tcagggaagt ccagtctggc ttttgatact ctctatgcgg agggacaacg tcgctatgta
     9301 gagagtttgt ctgcctacgc tcgtcagttc ttgggaaata tggaaaaacc agatgtagat
     9361 gccattgatg gtctcagccc agctatttcc atcgaccaga aaacgactag taaaaatcct
     9421 cgctcgacgg tgggaacgac gactgaaatc aatgactatc tgcgtctcct ctacgcacgt
     9481 gtggggacgc cttactgtat caacggacat ggagctatca atgcttcttc tgtggagcaa
     9541 atcgttgata aggttttgga gttacctgaa cgccagcgct tgcagatctt ggctcctgtc
     9601 atccgcaaga aaaaaggcca acataagagt gttatcgaga aggttcagaa agacgggtat
     9661 gttcgtgttc gtgtggatgg ggaagtctat gatgtgaccg aagtgccaga gttgtctaag
     9721 agcaagcaac acaatatcga tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt
     9781 agccgtctct ttgattccat tgaagctgct cttcgtatcg cagaaggtta tgtgattatc
     9841 gacaccatgg acgactctga gttgttgttc tctgagcatt atgcctgtcc agtttgtgga
     9901 tttactgtcc cagagttaga acctcgtctc ttctctttca atgctccctt tggctcttgt
     9961 agtgagtgtg acggcttggg gattaagctg gaggtggata ctgatttggt agtgccagat
    10021 gccagcaaaa ccttacatga gggagcgctg gcaccttgga atcctatctc atccaactac
    10081 tatccaaaca tgttagagca ggccatgaaa gtctttggag tggctatgga taagcctttt
    10141 gaggacctgt cagaagaaga taagaacttg attctctacg gctcagatgg taaggaattc
    10201 catttccatt atgaaaatga atttggtggt gtgcgcgata tcgacattcc gtttgaggga
    10261 gttatcaata atatcaaacg tcgttaccat gaaaccaata gcgattacac tcgcactcag
    10321 atgcgtctct acatgaatga gctgacctgc ggaacctgtc aaggctatcg tctcaatgac
    10381 caggccttgt ctgtccgtgt gggcggccag caagggccac atattggaga aatctcagac
    10441 ctgtctatcg ctgaccactt ggacttggtg agccagttaa ctttgtctga aaatgaagcc
    10501 atcattgctc gtcccattct caaggaaatc aaggatcgtt tgaccttcct taataatgtg
    10561 ggtcttaact atctaaccct gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag
    10621 cgcattcgtt tggcaaccca gattggttcc aacctatcag gtgtcctcta tatcctagac
    10681 gagccgtcaa tcggtcttca ccagagggac aatgaccgcc tgattgccag tctgaaaaag
    10741 atgcgtgact tgggcaatac tcttatcgtg gtggaacacg acgaagatac catgcgtgaa
    10801 gctgattatc tgattgacgt tggtcctggt gccggtgttt ttggtggtga gattgttgca
    10861 gcaggtacac ctaagcaagt ggctcgcaac agcaagtcta tcacaggtca gtacttgtca
    10921 ggcaaacgtg tcatcccagt accagaagag cgccgtgtcg gaaatggtcg ttttattgaa
    10981 gtgataggag cgcgtgagaa caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa
    11041 tttatcgcag tgacaggtgt gtcgggttca gggaaatcga ctctaatcaa cagcattctc
    11101 aaaaaagcca ttgcccagaa gctcaaccgt aattcagaca aacctggtaa gtttaagact
    11161 attacaggga ttgagcatgt cgaccgtttg attgatattg accagagccc tatcggacgg
    11221 acgccgaggt ctaacccagc tacctataca ggagtttttg acgatatacg tgaccttttt
    11281 gctcagacaa atgaagccaa gattcgaggc tacaagaagg ggcgcttcag tttcaacgtc
    11341 aagggaggtc gctgtgaagc ttgctcaggt gacgggatta tcaagattga gatgcacttc
    11401 ttgccagatg tttatgtggc ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc
    11461 ctagaagttc actacaagga aaagaatatt tcgcaggtct tggatatgac ggtcaacgat
    11521 gcggtagaat ttttccaaca cattccgaaa attcaacgca aactccagac catcaaggat
    11581 gtagggctag gctatgtgac cttgggacag ccagctacca ccctttctgg gggagaagcc
    11641 caacgtatga agttagctag cgaactccac aaacgctcga caggaaaatc tttctacatt
    11701 ctggatgagc cgacgacagg gcttcataca gaggacattg ctcgcctgct caaggtttta
    11761 gctcgctttg tagacgatgg caatacagtc ctcgtcatcg agcacaatct ggatgttatc
    11821 aagacggcag accatatcat tgacttggga cctgagggtg gtgtcggtgg tggaaccatc
    11881 atcgtaacag gaactccaga agaagtagct gccaacgaag ccagctatac aggacattat
    11941 ttgaaaggaa agttacatca tgaataaacg cgtacaagca tttctagcta aaatgcaaga
    12001 aaaagaacta gatggtatca tcatcaacaa tcttaaaaac gtctattatt tgactggttt
    12061 ttggggctca aacggaacag tctttatcag ccgtgaccgt caggtcttag tgacagactc
    12121 tcgctatatc atcgcagcta agcaagaaac cagtggtttt gagattgtgg ctgatcgtga
    12181 tgaattggct gtcattgcag gaattgttaa ggacatggac ttgactcgta tcggttttga
    12241 agatgagatt tcagtgtctt attaccaccg tatgcaggca gcttttgcag gtttggactt
    12301 gcttccacaa actcagtttg tggaaggtct tcgtatgatt aaggatgagg cagagattgc
    12361 agcgattcgc aaggcttgtt ctatctcaga ccaagctttc cgcgatgcgc ttgactttat
    12421 caaaccagga aaaactgaaa ttgagattgc caacttcctt gatttccgca tgcgtgagtt
    12481 gggagcatct ggcttatctt ttgatacgat cctagctagc ggtatcaatt cttctaaacc
    12541 ccatgcccat ccaatgcaca aaccagtgga gttgggagaa gccattacca tggacttcgg
    12601 ctgtctctat gaccactatg tcagtgatat gacccggact atctatctag ggcatgttag
    12661 cgatgagcag gcagagattt acaatacggt tctaaaagct aaccaagcct tgattgacca
    12721 agctaaggca ggcttaggtt tccgtgactt tgacaaaatc cctcgtgata ttatcattga
    12781 ggcaggttat ggcgactact ttacccacgg cattggccac ggtattggtc tggatatcca
    12841 tgaggaaccc tactttagcc agacttctac agaaactatt aagacaggta tggccttgac
    12901 cgatgaacca ggtatctata tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct
    12961 gattacagag acaggttgtg aattattgac cctagctcca aaagagttga tagtcattta
    13021 gttgtttgtc aagaaaaaag tacgaaaatg acgaaaaaag tcaaaaaaaa ttaaaaatag
    13081 gtcgcaagtc ggatgttttt tatggtataa tagactaaac tgatagtaac atgtagcgaa
    13141 aggggtaggt acatgattaa aatttataca gtctcaagtt gtactagctg taaaaaagca
    13201 aaaacctggc tcaatgccca ccagttaagt tataaagaac aaaaccttgg taaagaagga
    13261 attacgagag aagaattact ggatattcta accaaaacag ataacggaat agccagcatc
    13321 gtttcatcta aaaatcgcta tgccaaagcc cttggagtgg atattgaaga tttgagtgtc
    13381 aatgaagttc tcaatctgat tatggaaaca ccgagaattt taaagagccc aatccttgta
    13441 gatgaaaaac gcctgcaagt tggctacaag gaagacgata ttcgtgcctt cctaccacgc
    13501 tctgtccgta atgtagaaaa tgcagaagca cgtttgcgtg cagctctata aacatcaagg
    13561 ctgggagcac ttcccagtct tattctattt taatttcaaa aagaaagaag aaagaaatga
    13621 aaaaaatagt tcttgttagt ctagctttcc tttttgtcct ggttggttgc ggacagaaaa
    13681 aagaaactgg accagctaca aaaacagaaa aagatacgct tcagtcggca ttgccagtta
    13741 ttgaaaatgc tgagaagaat acagttgtaa ctaagacttt ggtcttgccc aagtcagatg
    13801 atggtagcca gcagacacaa acaattactt ataaagacaa gacttttttg agtctaacta
    13861 tccaacaaaa acgtccagtc tctgatgagt tgaagactta tattgaccaa catggagtgg
    13921 aggaaactca aaaagctctt cttgaagcgg aggagaagga taagtctatc attgaagctc
    13981 gtaaattggc aggtttcaaa cttgaaacaa aactattgag cgcaacggaa cttcaaacaa
    14041 cgactagttt tgattttcaa gttctggatg tcaagaaggc ttcccagttg gaacatctga
    14101 agaatattgg tttggaaaat cttttgaaaa atgaaccaag caaatatatt tcagatagat
    14161 tggcaaatgg cgcgacagaa caatagaaaa tccaaataaa tagactgcct gaattgtaga
    14221 aggtaaggaa ttatgctata atggtactat tctaaggaaa gagggtgtta gaatgggatt
    14281 tactgaagaa acagtacgtt ttaaattgga cgattccaat aaaaaagaaa ttagcgaaac
    14341 tttgacagat gtttatgctt cgttgaacga taagggttac aacccaatta accaaatcgt
    14401 aggttacgta ttgagtggag accctgccta cgttcctcgt tataataatg cacgaaatca
    14461 aatccgtaag tatgagcgtg atgaaatcgt tgaggaattg gttcgctact acctcaaagg
    14521 acaaggagtc gatctataac ctatgagaat tatgggattg gacgtcggtt caaaaacggt
    14581 aggggtggcg attagcgatc cgcttggttt tacagctcaa gggcttgaaa tcatccagat
    14641 aaatgaagaa caaggccaat ttggttttga ccgcgttaag gaattggttg atacttacaa
    14701 ggtggaacga tttgtagtgg gcttgcctaa aaacatgaac aatacaagtg gaccgcgcgt
    14761 agaagctagt caagcctacg gagcaaagct agaagagttt tttggtttac cagtagacta
    14821 tcaggatgaa cgcttgacaa cagtggctgc tgagcgcatg ttgattgaac aagcagatat
    14881 cagtcgcaat aagcgcaaga aagtcattga taagttagca gctcagctga ttttacaaaa
    14941 ttatttagat agaaaatttt aatataaagg agaggctatg tcacacgatc ataaccacga
    15001 ccacgaagaa cgtgaactaa tcacactagt agatgagcaa ggaaatgaaa ccttgtttga
    15061 aatccttttg acaattgatg gaaaagaaga atttggtaaa aactatgttc ttctagtacc
    15121 agttaacgca gaagaagacg aagacggaca agttgaaatc caagcttact cattcattga
    15181 aaatgaagat ggaacagaag gcgaattgca accaatccca gaagactcag aagacgaatg
    15241 gaacatgatt gaagaagtct tcaacagctt tatggaggag taaaaacgtc cgggggacgt
    15301 ttttagccct gcgctagaaa ttagaaacgc aggtagtctg ggagactgta tcagcccaac
    15361 tcccagaaat ggggaagagt tggaatgtcc agtggatgtt tttagcccag ttcctttaaa
    15421 taagatagaa ctggtaggtt cggggggacg tttttagccc atattcacat tcatagtagc
    15481 tagttattag ctaaccaggt aagaggtcgg gacgaaaatc ctggccttgt ttttattagt
    15541 aaccatactt taatgcgata attgattgga cttttgtcaa ggagatgtgt atgtttgaag
    15601 tagaagaatg gctccatagt cggattggtt tgaattttcg atcaggtttg ggccgaatac
    15661 agcaagcggt ggatttgtta ggaaatcctg agcagtctta ccctattatc cacgtaacag
    15721 ggactaatgg gaaaggatct accattgctt ttatgaggga attatttatg gggcatggca
    15781 aaaaagttgc gacctttacc tcccctcata tcgtctctat caatgaccga atctgcatta
    15841 atgggcaacc tatagcagat gcagacttta tccgtttggc tgatcaggtc aaggagatgg
    15901 agaaaacgct tctgcaaact cctgaccagt tgtccttttt tgaattgctg accttggttg
    15961 cttttcttta ttttagggag caagaggtgg atttggtttt attagaagtg ggaattggtg
    16021 gcttacttga cacgaccaat gtggtaactg gagagcttgc tgtcatcacc tccattgggc
    16081 ttgatcatca agaaaccttg ggtgatagtc tagaagcaat tgcagagcag aaagctggta
    16141 ttttcaagac tggtaagaag gcagtgattg caaaattgcc tccagaagct aggcttatct
    16201 gtcagaaaaa agccgaatct ttagctgtta acctttatca ggcaggtcaa gattttttaa
    16261 tgctgaatgg tgatttttca agctctttac taaatctttc acagctgaac ataggcttag
    16321 aaggagtcta tcagcaggag aatgcagcct tggcgttgca aacttttctt ctttttatgg
    16381 gagaaggaaa ggaagctgtt gatgaacagg ctgtaagaaa ggccttggaa cagacccatt
    16441 gggctggtcg cttggagcgt attcgcccac agatttactt ggatggtgct cataacctcc
    16501 ctgccttgac tcgcttggtt gagtttatca aagaaaaaga gcaggaaggt tatcgtcctc
    16561 aaatcctctt tggatccttg aaacggaagg attatcaagg gatgttgggt tatctgactg
    16621 aaaatttacc tcaagtggaa ctcaagatga ctggctttga ctatcaaggg tctttggacg
    16681 aaagggatgt gacaggttac gatatagttt cttcttaccg agaatttatc agcgattttg
    16741 aagaaagagc agatgctcag gatttgctgt tcgttacagg gtctctctat tttatctcag
    16801 aagtacgggg ctacctgctg gaccgtgagc agataaattg acccccttgt ttgaacttgt
    16861 tatactaggg aaattgctgg ttagagaaaa tttctctaaa ttggtagcag aaaggaaatt
    16921 catcatgaaa ttaaaaagat tcacactttc tcttgcttct ctagcaagtt ttagtctctt
    16981 agtagcttgt tcacaaagag ctcaacaggt tcaacagcct gttgctcagc agcaggtcca
    17041 acagcctgct caacaacctg ctcaacagaa taccaatact gcaaatgcag gaggtaacca
    17101 aaatcaagcg gctccagtac aaaaccaacc tgttgctcaa ccgaccgata ttgatgggac
    17161 ttatactggt caggatgacg gagaccgtat cactttagtg gtaactggaa cgactggtac
    17221 atggactgag ctcgaatctg acggggatca gaaagtcaaa caggttacat ttgattcagc
    17281 aaatcaacgc atgattattg gcgatgatgt caaaatttac actgtaaacg gtaatcaaat
    17341 cgtcgtagat gatatggata gagacccatc ggaccaaatc gttttaacta aataagacta
    17401 tgcaagtaga aagggctgga tttttcagcc tttttacttt tacctagaaa ataatcataa
    17461 atacttgcct tctaccgaat acctgcgtta tactagtatc aattacttgt ttttagcatt
    17521 caaactatca aggaggggat atgaaatata ggaaatttca attattgatg tccaagtatg
    17581 gctttagtct ttcgattatg ctacttgaac tttgtcttgt ttttggtctc tttctttatt
    17641 taggacgcat ggctcccatt ttatggatta ctgtcctcat tctactgagt atcatcacaa
    17701 tcatttcgat agtcaaccgt aatacgactc ctgagaataa ggtaacctgg ttgttagtag
    17761 cctttgtgcc agtatttggt cccttgctct atctgatgtt tggtgaaagg cgattgtcca
    17821 aaaaagaaat caaacaactg aagaagctag gctctatgca tttccaagaa gcaaatagcc
    17881 agctactaaa agagaaatta aaagaaagtg acaaggcagc ttatggagtc atcaagtcct
    17941 tattgagtat ggataccaat gctgacatct atgatcaaac tgcctctaca ttttttccta
    18001 acggagaagc tatgtggaaa aagatggtag aagatcttaa aaaggctgag aaatttattt
    18061 tcttggaata ttacattata gaagaaggtt tgatgtggaa tcgcatacta gatatactag
    18121 agcaaaaggt agctcagggt gtagaggtta agatgctcta tgatgatatc ggctgtatgg
    18181 ctactttaac aggagattat gcacatcgac ttcgtcagct gggcatcgag gcccataaat
    18241 tcaataaagt tattcctcgt ttgacagtgg cttataataa cagagatcat agaaaaatat
    18301 tgattgttga tggtcagata gcctatactg gtggggtcaa tctggcagat gagtacatta
    18361 accacgtcga gagatttggt tattggaagg atagtggaat tcgcttagac ggactagcag
    18421 taaaagctct gacacgctta tttttgacca cttggtacat taatcgagga gaaattagtg
    18481 attttgatca atatcattta gaaaatcatt ctatcccgag tgacggttta accattccat
    18541 acggaagtgg acccaagcca atttttcgag cgcaggtagg gaaaaaagtt tatcagagtt
    18601 taatcaatca agcaacagaa tcggtctata ttacgacacc ttatttgatt atagattatg
    18661 atttaacaga gacaatcaaa aatgcagcta tgagaggggt cgatgttcga attatcaccc
    18721 cttacatacc agataagaag ttcattcagt tagtcacgag aggagcttat cccgaccttc
    18781 tttctgctgg tgttcggatt tatgagtata gtccaggttt tattcatagt aagcagatgt
    18841 tggtagacga agattttgcg gtggtgggga caatcaatct cgactaccgg agcttggtac
    18901 accattatga aaatgcagtc ttactctata aaactctttc tataagggaa atcgcccgag
    18961 attttcgaaa tatatttgca gattctcagg aagtctatcc tcattctatc aaaacgagct
    19021 ggtatcaaaa gcttgtaaaa gaaatcgccc agctattcgc ccctatctta taagaaatct
    19081 aggacttagg atacaaacca gacctatttt tcttgtcttt tacgaataga aagaaagagg
    19141 aggggaattc atgctaacta aggaagaagt gaatgatatg attgagttca aacagacaca
    19201 tttacaccgc tttcgggaaa ttgaaacctt tgtgaaacta tgcaaaaaat cactcaaaca
    19261 gccatcgcaa gctgacaatc ctaggacttt ttgatatact aagacagata aattgaacag
    19321 gagaaacgat atgagtgtgt atggtagagt agaagaagtt cataaggaga atcgtgaacc
    19381 tctagaatac caaatcgaac aagaatcgca tcatcgtgaa tcaagtcgtc ttcctttggt
    19441 gaaaatttta ctatggagta cgcttgtaac ggggataact ctaggagtac cgctattact
    19501 cgacttaatg agtgcacaag aagtgcagga tttttatgca ggttgggcgc ttcatcagac
    19561 agggaagatt tacagcgact attatggaag tcaaggtttg ctttattatt tgctgactta
    19621 cgtgagtcag ggcggatttt tctttgccat ctttgagtgg ttagccttgg tagcaggagg
    19681 atttttcctt tttagatcag cggacacctt gacagagcaa ggagaccaag ctggacatct
    19741 ggtgactatt ttttacatgc tagttacagg tcttgctttt ggtggaggct atgcgactct
    19801 tttagcgctt cctttcttat tcgcagcctt tagtttagtt gcggcttacc taagcaatcc
    19861 aagccatgat aagggatttg tacggattgg gctagctttg gcaggcggat ttttctttgc
    19921 tcccttatca tcgctcctgt ttattgctgt agtgagttta ggcttgttgg tctttaacct
    19981 tgggcataga cgctttgcgc atgggttcta tcagtttctt gcagtggctt taggtttttc
    20041 acttgtcttt tatccaactg cctactatag tgctgcaaca ggaagttttg gggatgcgat
    20101 tagtggtatt cgttatccta ttgacagtat tcgctttgat tttacttcta aaattttaga
    20161 gaatatgttt ttttatggct tgttgtccct tggtttggga tttgtggttt gtatcttttt
    20221 aggtctcttt caaaccaaac cctttaaact atacgtcatt tcggttcctg caagtcttgt
    20281 ggtaatttta ggtttgattt tacttttctt ttcacaagag cctctgcacg cttcttattt
    20341 gatggtcgtc ttccctgttt tcctactttt attggtaacc aatattaaga gtcaacagag
    20401 ggggcgtagt gctagaagaa gccgaagaga aacgccagtt agcctatgga gtcgtttctt
    20461 caaaggaaat ctatatctgc tagtttttgg gtttgtctat cttttgtctg ttcctttttt
    20521 gatgaagttt gtcctttatc cagtacctta tcaagaacgt aatcgtcttg ctgatttggt
    20581 aaaagaggag acaaatacgg aagatactat ctatgcatgg gatgatactg cgactcttta
    20641 tcgtaagagt gagcgcttgt cgccatcggc gattttgtcc ccgttgcact atacagcaac
    20701 tgaggaaaat cgtaataagt tacttaatga cttgaaagaa aaacaaccta aggtgattgt
    20761 ggtaaatgac aaggtggtag tctggtctga agtggaaaca ctcttaaaag aaaattacca
    20821 acaagtaaag actgattact cagagtttaa agtctataaa attaaataac caaatcaata
    20881 tcttgtgtat ttttaaaaat tttaggattt ttaacacaag atattgattt ttctttttag
    20941 agtggtataa tactttttag aaagaacatt ttagaaaaga gcatgcatat gattgcacta
    21001 gaagaaaaaa ttacaatttt gccaactctc ttcgtcgaga aacgagatgg gagacgtgtt
    21061 gtatttgatg tggacaagat tgacaaggct ctccacaagg cggctgacaa ggttatggat
    21121 gtgacacccc tggttgaaaa acgcctcgat gatctgactg agcgaattat tacagaaatt
    21181 catagtcgct ttccacaggg aattaagatt tacgaaattc aaaatatcgt agaacatgaa
    21241 ctccttgaag ccaaagaata tgcgctggct gaggagtata ttacttatcg gacacagagg
    21301 gattttgagc gctcaaaagc gacggatatc aactttagta ttcataaact tctcaacaaa
    21361 gaccagacag ttgtcaatga aaatgctaat aaagacagtg atgtctttaa cactcagcgt
    21421 gatttgacag cagggattgt tgggaaatca atcggactgc aaatgcttcc taagcacgta
    21481 gccaatgccc accaaaaggg ggatatccac tatcacgatt tggactacag tccctatacc
    21541 cctatgacca actgctgttt gattgatttt aagggtatgt tggaaaatgg ttttaagatt
    21601 ggaaatgcag aggtagagag tcccaagtct atccaaactg cgacagcaca gatttctcaa
    21661 atcattgcca acgttgcttc tagccagtac ggtggctgtt cagctgaccg tatcgatgaa
    21721 attttggcgc cttatgcaga gaagaactat caaaaacatc tcaaagatgc agaagagtgg
    21781 gtattgcctg aaaaacggga agattacgct tggaagaaaa cgcaaaagga catctacgat
    21841 gccatgcaat ctcttgagta tgaaatcaat actctcttca cttcaaatgg acaaacacct
    21901 tttacttcgc taggttttgg tctgggaacc agtcgttttg aacgagaaat tcaaaaagct
    21961 attttaaaca ttcgcatcaa gggtcttggt tcagaacacc gtacggctat ctttcctaaa
    22021 cttattttca ctctgaaaag aggccttaat ttagaggaag gaactcccaa ctacgacatc
    22081 aagcagttgg ctcttgagtg tgcaaccaaa cggatgtatc cagatgtttt atcttacgat
    22141 aagattgttg acttgacagg atccttcaag gtgcctatgg gttgccgttc tttcctccaa
    22201 ggatggaagg atgaaaatgg tgtagaagtc aattcaggtc gcatgaatct gggtgttgtg
    22261 acggttaatc tgcctcgtat tgctcttgag tctgaaggtg atatgaataa gttctgggaa
    22321 atcttcaacg agcgaatgaa tatcgcagaa gatgctcttg tttaccgtgt cgaacgcact
    22381 aaagaggcga caccagcgaa tgctcctatt ctttatcagt acggtgcttt tggccatcgt
    22441 ctaggtaaag aagaaagtgt tgaccagctc tttaagaatc gtcgggcaac cgtttcgctg
    22501 ggctatatcg gcttgtatga agtagcgaca gttttctttg gtaacagctg ggaaagtaat
    22561 ccagatgcta aggaattcac gctagacatc attcacgata tgaaacgccg tgtagaagag
    22621 tggtcagacc aatatggcta ccatttctct atctactcaa caccatccga aagtctgaca
    22681 gaccgtttct gccgactaga tatagacaag tttggctcta ttcctgatat cacagacaag
    22741 gaatactaca ccaactcttt ccactacgat gttcgtaaaa atccaacacc gtttgaaaaa
    22801 ttggactttg agaaagtcta tccagaagca ggtgcgtcag gtggtttcat ccattattgt
    22861 gagtatccag tccttcagca aaatccaaag gccttggaag ctgtctggga ttatgcttat
    22921 gaccgtgtag gctatctagg caccaatact ccgattgacc gttgctacaa gtgtgacttt
    22981 gaaggggatt ttgaaccaac tgagagaggg tttgcttgtc caaactgtgg caatagcgac
    23041 cctaaaacag tagatgtggt gaagcgaact tgtggctacc taggtaatcc tcaagcaaga
    23101 ccgatggtca acgggcgtca caaggaaatc gctgcgcgtg tcaaacatat gaatggttca
    23161 acgattaaaa tagctgggca tcaagtaaca aattagaaag aaatgaaatg ggaaaatatc
    23221 aactagacga taaggggcgc gcacaagtga cccgttatca cgagaaacac tctaaaggtg
    23281 gagttggtaa gaaagaacgc ttgcttagct tcagagaaca atttttaaac aagaacaaga
    23341 aaaaataaaa gtgagagcca gctctcgctt ttctcatagt gggaggtaag gatggaatta
    23401 cgcagaccaa gattagcaga taaagaaagc tgttttagat atgatgacag agtttgaaaa
    23461 gagccaatca gcccatgatg gaggattttg ggatacagag aactttgtgt atgaagagtg
    23521 gttggaaaca aatattcaaa aagagatggg aataaacttg cctgaaaatc gcgttccatc
    23581 gatacagttc gtattgtttg gtgaatcagg ttgtgctcta agatttttga atctgcgatt
    23641 gagactgaat gagaggttac tgaattatgc tggccacatt ggctactcca ttcgtccatc
    23701 tgaaagaggc aagggttatg caaaagagac tctccgtcag ggcttgcaag ttgctaagga
    23761 aaagaacatc aagaaagctc tggtgacctg tagcgtgaat aatcctgcta gcagagcagt
    23821 cattctagca aatggtggaa tatttgagga tgctcgcaat ggagtcgagc gttattggat
    23881 agaggtagcg aatgaataat ccaaaaccac aagaatggaa aagcgaggaa cttagtcaag
    23941 gtcgtatcat tgactacaag gcctttaact ttgtggacgg cgaaggcgtg cgcaactctc
    24001 tctatgtatc aggctgtatg tttcactgcg agggatgtta taatgttgcg acttggtctt
    24061 ttaatgctgg cattccctat acagcagaat tagaagagca gattatggca gaccttgccc
    24121 aaccctatgt tcaaggcttg actttgctgg gaggggagcc ttttctcaat actggcattc
    24181 tcttgcctct agttaaacgc atccgaaagg aattgccaga caaggacatt tggtcctgga
    24241 ccggctacac ttgggaagaa atgatgttgg aaactccaga taaactggaa ttcttgtcac
    24301 tgattgacat tcttgtcgat ggaagatatg atcgaactaa gagaaatctt atgctccagt
    24361 ttcgaggttc atctaaccaa cgaattatcg atgtgcaaaa atcgctcaaa agtgggcaag
    24421 tagtgatttg ggacaagctc aatgacggaa aagaaagcta tgaacaggtg aagagagaat
    24481 gaagaaaaaa tgaagaaaaa agacttagta gaccaactag tctcagagat cgagacgggg
    24541 aaagtcagga cactgggaat atacggtcat ggagcttcag gtaaatcaac ctttgcacag
    24601 gaattgtacc aagctttaga ttctactaca gtaaatttgc tagaaacaga tccctatatc
    24661 acctcaggac gccatctggt agtacccaag gacgcgccga atcaaaaggt gacagccagt
    24721 ctgccagtgg cgcatgaact ggagagtttg cagagagata tccttgcctt gcaggcgggt
    24781 atggatgtct tgacaattga agaaccttgg aaggctagtg aggtcttgtc tggagccaaa
    24841 ccaattttga ttgtcgaagg gatgtctgtt ggctttctac ccaaggaact ctttgaaaaa
    24901 accatctgtt tctacacgga tgaggagacc gaattaaagc gacgccttgc tagagatacg
    24961 actgtgagaa atcgcgatgc atcctttata ttggctagcc atcagatgag acgggagcag
    25021 tatctgcgat actataaaga aactgagtct aaggcggata tcttagtgga ccaatcagaa
    25081 gataaatttg atgtcaagag gacttaactt atgtatagaa gaaatataga agaaaatccc
    25141 taattttaga aagaaaaagt aggaaaacag tttcatccca aaaaaacgaa aaaacctaac
    25201 aaatcccttg caatcgcagg ggatttgtgt tattctatta tggtgctgta aattacagcc
    25261 ttagttttga tgcaagaggt tgcgacacgc tcggttgcat tgccacgcaa caccgtgtcg
    25321 gttttcttgt ggagctagcc tattatctta aatagacgaa aaggagaaaa agatggcaaa
    25381 caaaaaaatc cgtatccgtt tgaaagctta cgaacaccgt acgcttgaca cagcggctgc
    25441 aaaaatcgta gaatcagcta ctcgtacagg tgcacaagtt gcgggtccaa tcccacttcc
    25501 aactgaacgt agcctctaca caatcattcg tgcgactcac aaatacaaag actctcgcga
    25561 acaatttgaa atgcgtacac acaaacgttt gatcgatatc gttaacccaa ctcaaaaaac
    25621 agttgatgcc ttgatgaaat tggatcttcc aagtggtgta aacgtagaaa tcaaacttta
    25681 atctaaaata taaaagagca gaggctggtg tttcaatcta attgaacacg ggctaaactc
    25741 ggtgtgaaaa agataaactt cctagtgtct gctagacact gcgtcagttt cctattttca
    25801 cgttgagttt gacgtccttt gtatcttaga cttgagcata aaaaacgctc gttaaaaact
    25861 ttttgaataa aaaatataga aaaggaacta ttttctcatg acaaaaggaa tcttagggaa
    25921 aaaagtggga atgactcaaa tcttcactga agctggcgaa ttgatccctg taacagttat
    25981 tgaagcaact ccaaacgttg ttcttcaagt taaaactgtt gaaacagacg gatacaacgc
    26041 tatccaagtt ggtttcgatg acaaacgcga agtattgagc aacaaacctg ctaaaggaca
    26101 tgtagcgaaa gctaacacgg ctcctaagcg cttcattcgt gaattcaaaa acgttgaagg
    26161 cttggaagtt ggcgctgaaa tcacagttga aacattcgca gctggagatg ttgttgacgt
    26221 aacgggtact tctaaaggta aaggtttcca aggtgttatc aaacgccacg gacaatcacg
    26281 tggaccaatg gctcacggtt ctcgttacca ccgtcgtcca ggttctatgg ggcctgttgc
    26341 acctaaccgc gtattcaaag gtaaaaacct tgcaggacgt atgggtggcg accgcgtaac
    26401 aattcaaaac cttgaagttg tacaagttgt tccagaaaag aacgttatcc ttatcaaagg
    26461 taacgtacca ggtgctaaga aatctcttat cactatcaaa tcagcagtta aagctggtaa
    26521 ataataaaga aaggggaaat cagtcacaat ggcaaacgta acattatttg accaaactgg
    26581 taaagaagct ggccaagttg ttcttaacga tgcagtattt ggtatcgaac caaatgaatc
    26641 agttgtgttt gatgtaatca tcagccaacg cgcaagcctt cgtcaaggaa cacacgctgt
    26701 taaaaaccgc tctgcagtat caggtggtgg acgcaaacca tggcgtcaaa aaggaactgg
    26761 acgtgctcgt caaggttcta tccgctcacc acaatggcgt ggtggtggtg ttgtcttcgg
    26821 accaactcca cgttcatacg gctacaaact tccacaaaaa gttcgtcgcc tagctcttaa
    26881 atcagtttac tctgaaaaag ttgctgaaaa caaattcgta gctgtagacg ctctttcatt
    26941 tacagctcca aaaactgctg aatttgcaaa agttcttgca gcattgagca tcgattctaa
    27001 agttattgtt atccttgaag aaggaaatga attcgcagct ctttcagctc gtaaccttcc
    27061 aaacgtgaaa gttgcaactg ctacaactgc aagtgttctt gacatcgcaa atagcgacaa
    27121 acttcttgtc acacaagcag ctatctctaa aatcgaggag gttcttgcat aatgaatttg
    27181 tatgatgtta tcaaaaaacc tgtcatcact gaaagctcaa tggctcaact tgaagcaggg
    27241 aaatatgtat ttgaagttga cactcgtgca cacaaacttt tgatcaagca agctgttgaa
    27301 gctgctttcg aaggtgttaa agttgccaat gttaacacaa tcaacgtaaa accaaaagct
    27361 aaacgtgttg gacgttacac tggttttact aacaaaacta aaaaagctat catcacactt
    27421 acagctgatt ctaaagcaat cgagttgttt gctgctgaag ctgaataatc taaggaggaa
    27481 atatcgtggg aattcgtgtt tataaaccaa caacaaacgg tcgccgtaat atgacttctt
    27541 tggatttcgc tgaaatcaca acaagcactc ctgaaaaatc attgcttgtt gcattgaaga
    27601 gcaaggctgg tcgtaacaac aacggtcgta tcacagttcg tcaccaaggt ggtggacaca
    27661 aacgtttcta ccgtttggtt gacttcaaac gtaataaaga caacgttgaa gcagttgtta
    27721 aaacaatcga gtacgatcca aaccgttctg caaacatcgc tcttgtacac tacactgacg
    27781 gtgtgaaagc atacatcatc gctccaaaag gtcttgaagt aggtcaacgt atcgtttcag
    27841 gtccagaagc agatatcaaa gtcggaaacg ctcttccact tgctaacatc ccagttggta
    27901 ctttgattca caacatcgag ttgaaaccag gtcgtggtgg tgaattggta cgtgctgctg
    27961 gtgcatctgc tcaagtattg ggttctgaag gtaaatatgt tcttgttcgt cttcaatcag
    28021 gtgaagttcg tatgattctt ggaacttgcc gtgctacagt tggtgttgtc ggaaacgaac
    28081 aacatggact tgtaaacctt ggtaaagcag gacgtagccg ttggaaaggt atccgcccaa
    28141 cagttcgtgg ttctgtaatg aaccctaacg atcacccaca cggtggtggt gaaggtaagg
    28201 caccagttgg tcgtaaagca ccatctactc catggggcaa acctgctctt ggtcttaaaa
    28261 ctcgtaacaa gaaagcgaaa tctgacaaac ttatcgttcg tcgtcgcaac gagaaataat
    28321 attaaactag tcgcttaagc aactagtaaa tccgccagct cggtagcgct ccataggagt
    28381 gcaagccgct gtggtacaac atttaaagga gaaaatataa aaatgggacg cagtcttaaa
    28441 aaaggacctt tcgtcgatga gcatttgatg aaaaaagttg aagctcaagc taacgacgaa
    28501 aagaaaaaag ttattaaaac ttggtcacgt cgttcaacga tcttcccaag tttcattggt
    28561 tacactattg cagtttatga cggacgtaaa cacgtacctg tttacatcca agaagacatg
    28621 gtaggccaca aacttggtga atttgcacca actcgtactt acaaaggtca cgctgcagac
    28681 gacaagaaaa cacgtagaaa ataaggagaa cataaatggc agaaattact tcagctaaag
    28741 caatggctcg tacagtacgt gtttcacctc gtaaatcacg tcttgttctt gataacatcc
    28801 gtggtaaaag cgtagccgat gcaatcgcaa tcttgacatt cactccaaac aaagctgctg
    28861 aaatcatctt gaaagttttg aactcagctg tagctaacgc tgaaaacaac tttggtttgg
    28921 ataaagctaa cttggtagta tctgaagcat tcgcaaacga aggaccaact atgaaacgtt
    28981 tccgtccacg tgcgaaaggt tcagcttcac caatcaacaa acgtacagct cacatcactg
    29041 tagctgttgc agaaaaataa ggaggtaaaa tcgtgggtca aaaagtacat ccaattggta
    29101 tgcgtgtcgg catcatccgt gattgggatg ccaaatggta tgctgaaaaa gaatacgcgg
    29161 attaccttca tgaagatctt gcaatccgta aattcgttca aaaagaactt gctgacgcag
    29221 cagtttcaac tattgaaatc gaacgcgcag taaacaaagt taacgtttca cttcacactg
    29281 ctaaaccagg tatggttatc ggtaaaggtg gtgctaacgt tgatgtactc cgtgcaaaac
    29341 ttaacaaatt gactggaaaa caagtacaca tcaacatcat cgaaatcaaa caacctgatt
    29401 tggatgctca ccttgtaggt gaaggaattg ctcgtcaatt ggagcaacgt gttgctttcc
    29461 gtcgtgcaca aaaacaagca atccaacgtg caatgcgtgc tggagctaaa ggaatcaaaa
    29521 ctcaagtatc aggtcgtttg aacggtgcag atatcgcccg tgctgaagga tactctgaag
    29581 gaactgttcc gcttcacaca cttcgtgcag atatcgatta cgcttgggaa gaagcagata
    29641 ctacatacgg taaacttggt gttaaagtat ggatctaccg tggtgaagtt cttccagctc
    29701 gtaaaaacac taaaggaggt aaataaccaa tgttagtacc taaacgtgtt aaacaccgtc
    29761 gtgagttccg tggaaaaatg cgcggtgaag caaaaggtgg aaaagaagta gcattcggtg
    29821 aatacggtct tcaagctaca actagccact ggatcactaa ccgccaaatc gaagctgctc
    29881 gtatcgccat gactcgttac atgaaacgtg gtggtaaagt ttggattaaa atcttcccac
    29941 acaaatcata cactgctaaa gctatcggtg tgcgtatggg atctggtaaa ggggcacctg
    30001 aaggttgggt agcaccagtt aaacgtggta aagtgatgtt cgaaatcgct ggtgtatctg
    30061 aagagattgc acgtgaagcg cttcgacttg ctagccacaa attgccagtt aaatgtaaat
    30121 tcgtaaaacg tgaagcagaa taaggagaag gcatgaaact taatgaagta aaagaatttg
    30181 ttaaagaact tcgtggtctt tctcaagaag aactcgcgaa gcgcgaaaac gaattgaaaa
    30241 aagaattgtt tgaacttcgt ttccaagctg ctactggtca attggaacaa acagctcgct
    30301 tgaaagaagt taaaaaacaa atcgctcgta tcaaaacagt tcaatctgaa gcgaaataat
    30361 agactaggga aggagaaatt tcaatggaac gcaataatcg taaagttctt gttggacgtg
    30421 ttgtatctga caaaatggac aagacaatca cagttgtagt tgaaacaaaa cgtaaccacc
    30481 cagtctatgg taaacgtatt aactactcta aaaaatacaa agctcatgat gaaaacaatg
    30541 ttgccaaaga aggcgatatc gtacgtatca tggaaactcg cccgctttca gctacaaaac
    30601 gtttccgtct tgtagaagtt gttgaagaag cggtcatcat ctaatcaaac ctgaaaggag
    30661 aaaactgaaa tgattcaaac agaaactcgt ttgaaagtcg cagacaacag cggtgctcgc
    30721 gaaatcttga ctatcaaagt tcttggtggt tcaggacgta aatttgcaaa catcggtgat
    30781 gttatcgtgg catctgtaaa acaagctact cctggtggtg cggttaaaaa aggtgacgtt
    30841 gttaaagcag ttatcgttcg tactaaatca ggtgctcgtc gtgctgatgg ttcatacatc
    30901 aaatttgacg aaaacgcagc agttatcatc cgtgaagaca aaactcctcg cggaacacgt
    30961 atctttggcc cagttgcacg tgaattgcgt gaaggtggct tcatgaagat cgtgtcactt
    31021 gctccagaag tactttaatt tttaggaaca aactagtccc ctagcttcaa gctagggtgc
    31081 ccttatgggc gtaagaaaaa tcaaggagaa acctaatgtt tgtaaaaaaa ggcgacaaag
    31141 ttcgcgtaat cgctggtaaa gacaagggaa cagaagctgt tgtccttact gcccttccaa
    31201 aagtaaacaa agttatcgtt gaaggtgtta acattgttaa gaaacaccaa cgtccaacta
    31261 acgagcttcc tcaaggtggt atcatcgaga aagaagcagc tatccacgta tcaaacgttc
    31321 aagttttgga caaaaatggt gtagctggtc gtgttggata caaatttgta gacggtaaaa
    31381 aagttcgcta caacaaaaaa tcaggcgaag tgcttgatta atcacgaagg aaaggagaag
    31441 tataatggca aatcgtttaa aagaaaaata tcttaatgaa gtagttcctg ctttgacaga
    31501 acaattcaac tactcatcag tgatggctgt gcctaaagta gataagattg ttttgaacat
    31561 gggtgttggt gaagctgtat caaacgctaa aagccttgaa aaagctgctg aagaattggc
    31621 acttatctca ggtcaaaaac cacttatcac taaagctaaa aaatcaatcg ccggcttccg
    31681 tcttcgtgaa ggtgttgcga tcggtgcaaa agttaccctt cgtggtgaac gtatgtacga
    31741 attcttggat aaattggtat cagtttcact tccacgtgta cgtgacttcc acggtgtccc
    31801 aacaaaatca tttgatggac gcgggaacta cacacttggt gtgaaagaac aattaatctt
    31861 cccagaaatc aacttcgatg acgttgacaa aactcgtggt cttgacatcg ttatcgtaac
    31921 aactgctaac actgacgaag agtcacgtgc attgcttaca ggccttggaa tgccttttgc
    31981 aaaataatat aggaggtaaa tctaatggct aaaaaatcaa tggtagctag agaggctaaa
    32041 cgccaaaaaa ttgttgaccg ttatgctgaa aaacgtgctg cattaaaggc ggcaggggac
    32101 tacgaaggtt tatctaaatt acctcgcaac gcctcaccga ctcgtttaca taatcgttgt
    32161 agagttacgg ggcgcccaca ttcagtttac cgcaaatttg gtctgagtcg tatcgctttt
    32221 cgcgaacttg cgcataaagg tcaaattcct ggtgtaacaa aagcatcttg gtaatttaag
    32281 atatcaaggg tgtcaaaact ccaagtaaaa ataggaaact tgacgaagaa actaaagttt
    32341 ctaggaaagt ttatcttttt cacacagagt ttagcccggg ttcaattggg cttgccaatt
    32401 tgaacccgag ctacagcttt ggcaaaaaag accaatttgc tttggagcat tgcttctgca
    32461 ttaaattgtc tatttttgct cgtgctgtta cgctctttgt atcatgtatt aactagcaag
    32521 tgcaacttgc aaactactag taagaggaga aaaacaaaat ggttatgact gacccaatcg
    32581 cagacttcct aactcgtatt cgtaatgcta accaagctaa acacgaagta cttgaagtac
    32641 ctgcatcaaa catcaaaaaa gggattgctg aaatccttaa acgcgaaggt tttgtaaaaa
    32701 acgttgaaat cattgaagat gacaaacaag gcgtcatccg tgtatttctt aaatacggat
    32761 caaatggtga gaaagttatc actaacttga aacgtgtttc taaaccagga cttcgtgtct
    32821 acaaaaaacg tgaagacctt ccaaaagttc ttaacggact tggaattgcc atcctttcaa
    32881 cttctgaagg tttgcttact gataaagaag cacgccaaaa gaatgttggt ggtgaggtta
    32941 tcgcttacgt ttggtaaaat caagatacaa agctcgtaaa gaacaaagca aaattaggaa
    33001 gttggagaag tttgtttaca aacaagccaa cttatctatt ttgcacagtt cttagagcgt
    33061 gttcagttca gctcttgaac taaataagta tctgaacccc gtgaaaactg gccgttctgg
    33121 cctgacaatt taacaggaga aaataaacat gtcacgtatt ggtaataaag ttatcgtgtt
    33181 gcctgctggt gttgaactcg ctaacaatga caacgttgta actgtaaaag gacctaaagg
    33241 agaacttact cgtgagttct caaaagatat tgaaatccgt gtggaaggta ctgaaataac
    33301 tcttcaccgt ccaaacgatt caaaagaaat gaaaactatc cacggaacta ctcgtgccct
    33361 tttgaacaac atggttgttg gtgtatcaga aggattcaag aaagaacttg aaatgcgtgg
    33421 ggttggttac cgtgcacagc ttcaaggatc taaacttgtt ttggctgttg gtaaatctca
    33481 tccagacgaa gttgaagctc cagaaggaat tacttttgaa cttccaaacc caacaacaat
    33541 cgttgttagc ggaatttcaa aagaagtagt tggtcaaaca gctgcttacg tacgtagcct
    33601 tcgttcacca gaaccatata aaggtaaagg tatccgttac gttggtgaat tcgttcgccg
    33661 taaagaaggt aaaacaggta aataatgttg agtggttgat catcaaccac caacctattt
    33721 tccaactttg tgcatagcac acgatttaaa actaaagagg tgaaaactgt gatttcaaaa
    33781 ccagataaaa acaaactccg ccaaaaacgc caccgtcgcg ttcgcggaaa actctctgga
    33841 actgctgatc gcccacgttt gaacgtattc cgttctaata caggcatcta cgctcaagtg
    33901 attgatgacg tagcgggtgt aacgctcgca agtgcttcaa ctcttgataa agaagtttca
    33961 aaaggaacta aaactgaaca agccgttgct gtcggtaaac tcgttgcaga acgtgcaaac
    34021 gctaaaggta tttcagaagt ggtgttcgac cgcggtggat atctatatca cggacgtgtg
    34081 aaagctttgg ctgatgcagc tcgtgaaaac ggattgaaat tctaatagga ggacactaga
    34141 aaatggcatt taaagacaat gcagttgaat tagaagaacg cgtagttgct gtcaaccgtg
    34201 ttacaaaagt tgttaaaggt ggacgtcgtc ttcgtttcgc agctcttgtt gttgttggtg
    34261 accacaatgg tcgcgtagga tttggtactg gtaaagctca agaagttcca gaagcaatcc
    34321 gtaaagcagt agatgatgct aagaaaaact tgatcgaagt tcctatggtt ggaacaacaa
    34381 tcccacacga agttctttca gaattcggtg gagctaaagt attgttgaaa cctgctgtag
    34441 aaggttctgg agttgccgct ggtggtgcag ttcgtgccgt tgtggaattg gcaggtgtgg
    34501 cagatattac atctaaatca cttggttcta acactccaat caacattgtt cgtgcaactg
    34561 ttgaaggttt gaaacaattg aaacgcgctg aagaaattgc tgcccttcgt ggtatttcag
    34621 tttctgattt ggcataagaa aggggataaa atggctcaaa ttaaaattac tttgactaag
    34681 tctccaatcg gacgcattcc atcacaacgt aaaactgttg tagcacttgg acttggcaaa
    34741 ttgaacagct ctgttattaa agaagataac gctgctatcc gtggtatgat cacagcagta
    34801 tctcacttag taacagttga agaagtaaac taatgaagtt ttaggggatg tgcactgtac
    34861 catcccctaa aactagatat agtcatctat gatgacatcg tataggcgag ttgatggggg
    34921 agacaacctt ttctccctta tcggcgctag cattttacaa aagaggagaa aataaaaatg
    34981 aaacttcatg aattgaaacc tgcagaaggt tctcgtaaag tacgtaaccg cgttggtcgt
    35041 ggtacttcat caggtaacgg taaaacatct ggtcgtggtc aaaaaggtca aaaagctcgt
    35101 agcggtggcg gagttcgcct tggttttgaa ggtggacaaa ctccattgtt ccgtcgtctt
    35161 ccaaaacgtg gattcactaa catcaacgct aaagaatacg caattgtgaa ccttgaccaa
    35221 ttgaacgtct ttgaagatgg tgctgaagta actccagttg ttcttatcga agcaggaatt
    35281 gttaaagctg aaaagtcagg tattaaaatt cttggtaacg gtgagttgac taagaaattg
    35341 actgtgaaag cagctaaatt ctctaaatca gctgaagaag ctatcactgc taaaggtggt
    35401 tcagtagaag tcatctaaga gaggtgacct atgtttttta aattattaag agaagctctt
    35461 aaagtcaagc aggttcgatc aaaaatttta tttacaattt ttatcgtttt ggtctttcgt
    35521 atcggaacta gcattacagt tcctggtgtg aatgccaata gcttgaatgc tttaagtgga
    35581 ttatccttct taaacatgtt gagcttggtg tcggggaatg ccctaaaaaa cttttcgatt
    35641 tttgccctag gagttagtcc ctatatcact gcttctattg ttgtccaact cttgcaaatg
    35701 gatattttac ccaagtttgt agagtggggt aaacaagggg aagtaggtcg aagaaaattg
    35761 aatcaagcta ctcgttatat tgctctagtt ctcgcttttg tgcaatctat cgggattaca
    35821 gctggtttta ataccttggc tggagctcaa ttgattaaaa ctgctttaac tccacaagtt
    35881 tttctgacga ttggtatcat cttaacagct ggtagtatga ttgtcacttg gttgggtgag
    35941 caaattacag ataagggata cggaaacggt gtttccatga ttatctttgc cgggattgtt
    36001 tcttcaattc cagagatgat tcagggcatc tatgtggact actttgtgaa cgtcccaagt
    36061 agccgtatca cttcatctat cattttcgta atcattttga ttattactgt attgttgatt
    36121 atttacttta caacttatgt tcaacaagca gaatacaaaa ttccaatcca atatactaag
    36181 gttgcacaag gtgctccatc tagctcttac cttccgttaa aggtaaaccc tgctggagtt
    36241 atccctgtta tctttgccag ttcgattact gcagcgcctg cggctattct tcagtttttg
    36301 agtgccacag gtcatgattg ggcttgggta agggtagcac aagagatgtt ggcaactact
    36361 tctccaactg gtattgccat gtatgctttg ttgattattc tctttacatt cttctatacg
    36421 tttgtacaga ttaatcctga aaaagcagca gagagcctac aaaagagtgg tgcctatatc
    36481 catggagttc gtcctggtaa aggtacagaa gaatatatgt ctaaacttct tcgtcgtctt
    36541 gcaactgttg gttccctctt ccttggtgtg atttccattt taccgattgc agctaaagat
    36601 gtatttggtc tttctgatgt tgttgccttt ggtggaacaa gtctcttgat cattatctct
    36661 acaggtatcg aaggaatcaa gcaattggaa ggttacctat tgaaacgtaa gtatgttggt
    36721 ttcatggaca gaacagaata aaagtattta ctgaatcagt aaatgctgag ggagtggagg
    36781 tttaaactct gacatttgta agagttggat ctcccctctt ctattttgtt tttaaatagg
    36841 ggtgaaaaga ctttttgctt ctatttaaaa ataaaataag gagatcaaat catgaatctt
    36901 ttgattatgg gcttacctgg tgcaggtaag ggaactcaag cagcaaaaat cgtagaacaa
    36961 ttccatgttg cacatatctc aacaggtgat atgttccgcg ctgcaatggc aaatcaaact
    37021 gaaatgggtg ttcttgctaa gtcatatatt gacaagggtg aattggttcc tgacgaagtt
    37081 acaaatggaa tcgtaaaaga acgcctttca caagatgata ttaaagaaac aggattctta
    37141 ttggatggtt acccacgtac aattgaacaa gctcatgcct tggacaaaac attggctgaa
    37201 cttggcattg aactagaagg tgttatcaat attgaagtga accctgacag cctcttggaa
    37261 cgtttgagtg gccgtatcat ccaccgcgta actggagaaa ctttccacaa ggtctttaac
    37321 ccaccagttg actataaaga agaagattac taccaacgtg aagatgataa gcctgagaca
    37381 gtaaaacgtc gtttggatgt taatattgct caaggagaac caatcattgc tcactaccgt
    37441 gccaaaggtt tggttcatga catcgaaggt aatcaagata tcaatgatgt cttctcagat
    37501 attgaaaaag tattgacaaa tttgaaataa agcgtttttc atacttgcaa aaattcgcta
    37561 caaatgttat actgagatag tctgacttat aattgttgtc tctgtgtcta gaggcatcga
    37621 atcgaaattt atggaggtgc ttttgcgtgg caaaagacga tgtgattgaa gttgaaggca
    37681 aagtagttga tacaatgccg aatgcaatgt ttacggttga acttgaaaat ggacatcaga
    37741 ttttagcaac agtttctggt aaaattcgta aaaactatat tcgtatttta gcgggagatc
    37801 gtgttactgt cgaaatgagt ccatatgact tgacacgtgg acgtatcact taccgcttta
    37861 aataatcgaa aaacttggag ggataagaaa tgaaagtaag accatcggtc aaaccaattt
    37921 gcgaatactg taaagttatt cgtcgtaatg gtcgtgttat ggtaatttgc ccagcaaatc
    37981 caaaacacaa acaacgtcaa ggataagata gaaaggagaa aacatggctc gtattgctgg
    38041 agttgatatt ccaaatgaca aacgcgtagt aatctcattg acttatgttt atggtatcgg
    38101 acttgcaaca tctaagaaaa ttttggctgc tgctggaatc tcagaagatg ttcgtgtacg
    38161 tgatcttaca tcagatcaag aagatgctat ccgtcgtgaa gtggatgcaa tcaaagttga
    38221 aggtgacctt cgtcgtgaag taaacttgaa catcaaacgt ttgatggaaa tcggttcata
    38281 ccgtggtatc cgtcaccgtc gtggacttcc tgtccgtgga caaaacacta aaaacaacgc
    38341 tcgcactcgt aaaggtaaag ctgttgcgat tgctggtaag aaaaaataat ataggaggta
    38401 aaagtcttgg ctaaaccaac acgtaaacgt cgtgtgaaaa agaatatcga atctggtatt
    38461 gctcatattc acgctacatt taataacact attgttatga ttactgatgt gcatggtaat
    38521 gcaattgctt ggtcatcagc tggtgctctt ggtttcaaag gttctcgtaa atctacacca
    38581 ttcgctgctc aaatggcttc tgaagctgct gctaaatctg cacaagaaca cggtcttaaa
    38641 tcagttgaag ttactgtaaa aggtccaggt tctggtcgtg agtcagctat tcgtgcgctt
    38701 gctgccgctg gtcttgaagt aacagcaatt cgtgatgtga ctccagtgcc acacaatggt
    38761 gctcgtcctc caaaacgtcg ccgtgtataa tcatcgcatt acactgcttt tcgtttaaga
    38821 gggagtaact aaatgatcga gtttgaaaaa ccaaatataa caaaaattga tgaaaataaa
    38881 gattatggca agtttgtaat cgaaccactt gaacgtggct acggtacaac tcttggtaac
    38941 tctcttcgtc gtgtacttct agcttctcta ccaggagcag ctgtgacatc tatcaacatt
    39001 gatggtgtgt tacatgagtt tgacacagtt ccaggtgttc gtgaagacgt gatgcaaatc
    39061 attctgaaca ttaaaggaat tgcagtgaaa tcgtacgttg aagacgaaaa aatcatcgaa
    39121 ctggatgttg aaggtcctgc tgaagtaaca gctggtgaca ttttgacaga tagcgatatt
    39181 gaaattgtaa atccagatca ttatctcttt acaatcggtg aaggttcttc tctaaaagcg
    39241 actatgactg ttaacagtgg tcgtggatat gtacctgctg atgaaaataa aaaggataat
    39301 gcaccagttg gaacacttgc tgtagattct atttatacac cagttacaaa agtcaactat
    39361 caagtggaac ctgctcgtgt aggtagcaat gatggtttcg acaaattaac ccttgaaatc
    39421 ttgacaaatg gaacaattat tccagaagat gctttagggc tttcagcacg tattttgaca
    39481 gaacatcttg atttgtttac aaatcttact gagattgcta agtcaactga agtgatgaaa
    39541 gaagctgata ctgaatctga cgaccgtatt ttagatcgta cgattgagga actggacttg
    39601 tctgtgcgtt catacaactg tttaaaacgt gccggtatca atactgtgca tgatttgaca
    39661 gaaaaatctg aagcagagat gatgaaagta cgaaatcttg gacgcaagag tttggaagaa
    39721 gtgaaactca aactcattga tttgggtctt ggattaaaag ataaataaag gaggaataca
    39781 tggcttaccg taaactagga cgcactagct cacaacgtaa agcaatgctt cgcgatttga
    39841 caactgacct tttgatcaac gaatcaatcg tgacaactga agctcgtgct aaagaaatcc
    39901 gtaaaactgt tgaaaaaatg attactctag gtaaacgtgg tgatttgcat gcacgtcgtc
    39961 aagcagctgc tttcgtacgt aatgaaatcg catctgaaaa ctatgatgaa gcaactgata
    40021 agtacacttc tactacagca cttcaaaaat tgttctcaga aatcgcacct cgttatgctg
    40081 aacgtaacgg tggatacact cgtatcctta aaactgaacc acgtcgtggt gatgcagcgc
    40141 caatggcgat catcgaatta gtataaaatc atcaattttg ttgagtgtta tgatgatgga
    40201 gtcttgtgct cttagtctag ctctggtcta ccgctaggat ttcggtccta gcgggaacac
    40261 tcatcataag ttgggatagt agacgcttgt ttacgaaatt gtttttttct taagaacaac
    40321 ttcgtaagca ggcgtttttg agtattttcg ttagaattat gctatactat
//
LOCUS       DAVLZS010000016        40364 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLZS010000016 DAVLZS010000000
VERSION     DAVLZS010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.016"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            3..75
                     /locus_tag="VYO88_000880"
     tRNA            3..75
                     /locus_tag="VYO88_000880"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Val,seq:tac)
     gene            81..151
                     /locus_tag="VYO88_000881"
     tRNA            81..151
                     /locus_tag="VYO88_000881"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:113..115,aa:Gly,seq:tcc)
     gene            186..259
                     /locus_tag="VYO88_000882"
     tRNA            186..259
                     /locus_tag="VYO88_000882"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:Ile,seq:gat)
     gene            342..431
                     /locus_tag="VYO88_000883"
     tRNA            342..431
                     /locus_tag="VYO88_000883"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:378..380,aa:Ser,seq:tga)
     gene            445..518
                     /locus_tag="VYO88_000884"
     tRNA            445..518
                     /locus_tag="VYO88_000884"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:479..481,aa:Met,seq:cat)
     gene            522..594
                     /locus_tag="VYO88_000885"
     tRNA            522..594
                     /locus_tag="VYO88_000885"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:555..557,aa:Phe,seq:gaa)
     gene            607..687
                     /locus_tag="VYO88_000886"
     tRNA            607..687
                     /locus_tag="VYO88_000886"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:641..643,aa:Tyr,seq:gta)
     gene            692..762
                     /locus_tag="VYO88_000887"
     tRNA            692..762
                     /locus_tag="VYO88_000887"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:724..726,aa:Trp,seq:cca)
     gene            777..849
                     /locus_tag="VYO88_000888"
     tRNA            777..849
                     /locus_tag="VYO88_000888"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:810..812,aa:His,seq:gtg)
     gene            860..931
                     /locus_tag="VYO88_000889"
     tRNA            860..931
                     /locus_tag="VYO88_000889"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:892..894,aa:Gln,seq:ttg)
     gene            941..1024
                     /locus_tag="VYO88_000890"
     tRNA            941..1024
                     /locus_tag="VYO88_000890"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:975..977,aa:Leu,seq:caa)
     gene            1131..2408
                     /locus_tag="VYO88_000891"
     CDS             1131..2408
                     /locus_tag="VYO88_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1719014.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETMIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2484..3968
                     /locus_tag="VYO88_000892"
     CDS             2484..3968
                     /locus_tag="VYO88_000892"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1719015.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     NKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVTGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAELMNALNSQGQYELTNFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQATTGDATKTVIASTASPYKFPVVAVEALTGKVGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTIVAAADMQVAVEAYLGL"
     gene            4029..5309
                     /locus_tag="VYO88_000893"
     CDS             4029..5309
                     /locus_tag="VYO88_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1719016.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTETVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMNLKG"
     gene            5313..5933
                     /locus_tag="VYO88_000894"
     CDS             5313..5933
                     /locus_tag="VYO88_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1719017.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6099..7211
                     /locus_tag="VYO88_000895"
     CDS             6099..7211
                     /locus_tag="VYO88_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1719018.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEATTTSSEAKEVASSN
                     GATAAVSTYQSEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7534..7959
                     /locus_tag="VYO88_000896"
     CDS             7534..7959
                     /locus_tag="VYO88_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1719019.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7970..8338
                     /locus_tag="VYO88_000897"
     CDS             7970..8338
                     /locus_tag="VYO88_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV1719020.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8445..9055
                     /gene="pcp"
                     /locus_tag="VYO88_000898"
                     /pseudo
     CDS             8445..9055
                     /gene="pcp"
                     /locus_tag="VYO88_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9116..9973)
                     /locus_tag="VYO88_000899"
     CDS             complement(9116..9973)
                     /locus_tag="VYO88_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1719021.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYQA
                     VLARKRPKA"
     gene            10103..11245
                     /gene="tgt"
                     /locus_tag="VYO88_000900"
     CDS             10103..11245
                     /gene="tgt"
                     /locus_tag="VYO88_000900"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1719022.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11343..13160
                     /locus_tag="VYO88_000901"
     CDS             11343..13160
                     /locus_tag="VYO88_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1719023.1"
                     /translation="MRIKWFSLIRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13313..14464
                     /gene="nagA"
                     /locus_tag="VYO88_000902"
     CDS             13313..14464
                     /gene="nagA"
                     /locus_tag="VYO88_000902"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1719024.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVEPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14627..15685
                     /locus_tag="VYO88_000903"
     CDS             14627..15685
                     /locus_tag="VYO88_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1719025.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15836..16201
                     /locus_tag="VYO88_000904"
     CDS             15836..16201
                     /locus_tag="VYO88_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1719026.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16277..17218
                     /locus_tag="VYO88_000905"
     CDS             16277..17218
                     /locus_tag="VYO88_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1719027.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17166..18182
                     /locus_tag="VYO88_000906"
     CDS             17166..18182
                     /locus_tag="VYO88_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1719028.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18184..18510
                     /gene="comGC"
                     /locus_tag="VYO88_000907"
     CDS             18184..18510
                     /gene="comGC"
                     /locus_tag="VYO88_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV1719029.1"
                     /translation="MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            18503..18907
                     /locus_tag="VYO88_000908"
     CDS             18503..18907
                     /locus_tag="VYO88_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1719030.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18912..19172
                     /locus_tag="VYO88_000909"
     CDS             18912..19172
                     /locus_tag="VYO88_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719031.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19135..19596
                     /locus_tag="VYO88_000910"
     CDS             19135..19596
                     /locus_tag="VYO88_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1719032.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKEIAMGKSKADDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19574..20022
                     /locus_tag="VYO88_000911"
                     /pseudo
     CDS             19574..20022
                     /locus_tag="VYO88_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
     gene            20125..20712
                     /locus_tag="VYO88_000912"
     CDS             20125..20712
                     /locus_tag="VYO88_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1719033.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKVILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQARLKAEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVNSQILYSAEDLFQGNHSEFFLTVSQKSLA"
     gene            20773..21726
                     /locus_tag="VYO88_000913"
     CDS             20773..21726
                     /locus_tag="VYO88_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1719034.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGAIFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21777..22967
                     /locus_tag="VYO88_000914"
     CDS             21777..22967
                     /locus_tag="VYO88_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1719035.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23115..23486
                     /gene="rnpA"
                     /locus_tag="VYO88_000915"
     CDS             23115..23486
                     /gene="rnpA"
                     /locus_tag="VYO88_000915"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1719036.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23461..24285
                     /locus_tag="VYO88_000916"
     CDS             23461..24285
                     /locus_tag="VYO88_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1719037.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24304..25290
                     /locus_tag="VYO88_000917"
     CDS             24304..25290
                     /locus_tag="VYO88_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1719038.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25341..25964
                     /locus_tag="VYO88_000918"
     CDS             25341..25964
                     /locus_tag="VYO88_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1719039.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26095..27552
                     /locus_tag="VYO88_000919"
     CDS             26095..27552
                     /locus_tag="VYO88_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1719040.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27575..27856
                     /locus_tag="VYO88_000920"
     CDS             27575..27856
                     /locus_tag="VYO88_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1719041.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27933..28418
                     /locus_tag="VYO88_000921"
     CDS             27933..28418
                     /locus_tag="VYO88_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1719042.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28435..29100
                     /locus_tag="VYO88_000922"
     CDS             28435..29100
                     /locus_tag="VYO88_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1719043.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLVDMGFRVSVTGGLDVDTLKLFEGVDIFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29104..29967
                     /locus_tag="VYO88_000923"
     CDS             29104..29967
                     /locus_tag="VYO88_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1719044.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            29969..30673
                     /locus_tag="VYO88_000924"
     CDS             29969..30673
                     /locus_tag="VYO88_000924"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1719045.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVTYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30852..32524
                     /locus_tag="VYO88_000925"
                     /pseudo
     CDS             30852..32524
                     /locus_tag="VYO88_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
     gene            32636..33727
                     /gene="ulaG"
                     /locus_tag="VYO88_000926"
     CDS             32636..33727
                     /gene="ulaG"
                     /locus_tag="VYO88_000926"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1719046.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33841..35817
                     /gene="tkt"
                     /locus_tag="VYO88_000927"
     CDS             33841..35817
                     /gene="tkt"
                     /locus_tag="VYO88_000927"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1719047.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMNEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35934..36233
                     /gene="yajC"
                     /locus_tag="VYO88_000928"
     CDS             35934..36233
                     /gene="yajC"
                     /locus_tag="VYO88_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1719048.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELTAIKTVLPLKETASLEGAIEK"
     gene            36280..36708
                     /locus_tag="VYO88_000929"
     CDS             36280..36708
                     /locus_tag="VYO88_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1719049.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36710..37120
                     /locus_tag="VYO88_000930"
     CDS             36710..37120
                     /locus_tag="VYO88_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719050.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGSFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37421..40072
                     /gene="adhE"
                     /locus_tag="VYO88_000931"
                     /gene_synonym="adhC"
     CDS             37421..40072
                     /gene="adhE"
                     /locus_tag="VYO88_000931"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1719051.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12211 a         7247 c         9105 g        11801 t
ORIGIN      
        1 tagggagttt agctcagctg ggagagcatc tgccttacaa gcagagggtc agcggttcga
       61 tcccgttaac tcccatttta gcgggtgtag tttagtggta aaactacagc cttccaagct
      121 gttgtcgcga gttcgattct cgtcacccgc tttgaacttt gttctttgta ccaagttttt
      181 gacttgggcg cgtagctcag gtggttagag cgcacgcctg ataagcgtga ggtcggtggt
      241 tcgagtccac tcgtgcccat agtgtttagt ccattactag gggattggaa tattatctgt
      301 tcactaagag gacacgggct tgttcccgta taaactattt tggaggatta cccaagtccg
      361 gctgaaggga acggtcttga aaaccgtcag gcgtgtaaaa gcgtgcgtgg gttcgaatcc
      421 cacatcctcc ttttatatta ttaacgcggg atggagcagc tcggtagctc gtcgggctca
      481 taacccgaag gtcgtaggtt caaatcctgc tcccgcaata aggctcggta gctcagttgg
      541 tagagcaatg gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccatttata
      601 tattttggaa gggtagcgaa gaggctaaac gcggcggact gtaaatccgc tccttcgggt
      661 tcgggggttc gaatccctcc ccttccattt tacgggcata gtttaaaggt agaactaagg
      721 tctccaaaac cttcagtgtg ggttcaattc ctactgcccg tgttaataga attatggcgg
      781 gtgtggtgaa gtggttaaca caccagattg tggctctggc atgcgtgggt tcgatcccca
      841 tcactcgcct attttatatt ggggtatagc caagcggtaa ggcaagggac tttgactccc
      901 tcatgcgttg gttcgaatcc agctacccca gttactattt gccggcgtgg cggaattggc
      961 agacgcgctg gactcaaaat ccagtgtccg caaggacgtg ccggttcgac cccggccgcc
     1021 ggtatagtat agtgttagga acgttgttat tcttcgttcc ttttttatat tatttttggt
     1081 ataattatag ttattcaaat tttatttaga ttaagaaagt gtaggggagt atgtcttgtt
     1141 ctatcgattt attaaaacat cggtatttga aaaatattaa agaaaatcct gaattgtttg
     1201 tcggaattga gttggagtat cctgttgcaa gtttagaagg ggatgctaca gatgttgaag
     1261 ttataaagga tctatttcat tatttagttt ctactttgga tctcaccgta gcaaaggtag
     1321 atgattttgg caatctgatc cagttagtag atccgataag tcaggatgct attttatttg
     1381 aagtttccta tacaacgatt gagtttgcat ttggtaaggc tgaaacgatt caagaggtcg
     1441 aaaatcgttt caataattat atgaatgtaa ttcagagaaa gttagctgaa tcaaatcatg
     1501 ctattgttgg ctgtggtatc catcccaact gggataaaaa tgagaattgt ccagtggctt
     1561 atccacgcta tcagatgttg atggattatt tgaatttgag tagaaatatt attaaatcag
     1621 atttacatca tttccctgaa tatggtactt ttatctgtgg gagccaggtt cagctggata
     1681 tttcaaaaac caactacttg cgggtgatta atgcttttac tcaaattgaa gcggctaagg
     1741 cttatttatt tgcaaactct gagttttcgg gtgcggattg ggatacgaaa atttcaaggg
     1801 atattttctg ggaagaatct atgcatggta tctatccaga gaatgttggg gtcaatgcta
     1861 gactccttaa tgatgaagct gatttttttg actatctaaa tcattctgcg atttttactg
     1921 cggaacgtga tgggcagacc tattattttt atcctattca ggctggggac tatttggcta
     1981 cgcctgaaat ccaagcattt gctctgaatg gggatgaggt tattatttac ccccaagaga
     2041 aggattttga aactcatcgt agttaccagt accaagactt aacgactcga ggaacagttg
     2101 agtttcgtag tgtgtgtaca cagccacttg ataggacttt tgcttctgca gcttttcact
     2161 tgggattatt ggttaattta gacaagttag aagcttactt agaaacagca cctttcttta
     2221 aagtatttgg ttatgattac aagtttttaa ggagacaatt ttctaagaaa aatcttacag
     2281 atgaggaaga aactatgatt attgaatttt ccaaagactt actcctacta gctgaggagg
     2341 gactagtggt gagaaataag gaagaaatga cctatttaca gcctttgaga gaagaattga
     2401 gcctataatt tctcttataa agggagaatt ttctgaaaaa tcatgatata atggacgaga
     2461 ctatagataa aggatagaga gtaatgacat tagtttatca atcaacgcgt gatgccaaca
     2521 atacagtaac tgccagccaa gcaattttgc aaggtttggc gacggacggc ggtttgttta
     2581 caccggttac ttatccaaag gtagatttga actttaacaa attgaaagat gcttcttacc
     2641 aggaagttgc taagctagtt ttgtcagcat ttttagatga ctttacagct gaggagttgg
     2701 actactgtat caacaatgcc tacgatagca aatttgatac tccagctatt gcaccattag
     2761 tgaaattaga tgggcaatac aatttggaac ttttccatgg ttcaacgatt gcctttaagg
     2821 atatggcctt gtctattttg ccatacttta tgacgactgc tgctaagaaa catggtttgg
     2881 agaacaagat tgttatcttg acagcgacat ctggtgacac ggggaaagct gctatggcgg
     2941 ggtttgcgga tgtgcctggt actgagatta tcgtctttta tccaaaggat ggtgtcagca
     3001 agattcaaga gttacaaatg accactcaaa ctggcgacaa tactcatgtt attgctattg
     3061 atggtaactt tgacgatgcg caaacaaatg tgaagcacat gtttaacgac gtggctcttc
     3121 gtgaaaaatt gactaccaac aagttgcaat tttcatcagc taactctatg aacattggtc
     3181 gtctggtgcc acaaattgtt tattatgttt atgcttacgc tcaattggtc aagactggtg
     3241 agatcgtgac tggtgataag attaacttca cagtaccaac aggaaacttt ggaaatatct
     3301 tggctgcctt ttatgccaaa caaatcggtc tcccagttgg taaattgatc tgtgcttcaa
     3361 atgacaacaa tgttttgaca gacttcttca agacacgtgt ctatgacaag aaacgtgagt
     3421 ttaaggtaac aaccagccca tctatggata tcttggtatc ttcaaacttg gagcgtttga
     3481 ttttccatct tttggggaat gatgcggtta agacggctga actcatgaat gctttgaata
     3541 gccaaggtca atatgagttg actaattttg atgcagagat tttggacctc tttgcagctg
     3601 aatatgcgac tgaggaagaa actgcggcag aaatcaagcg tgtttatgag tcagattctt
     3661 atatcgagga tcctcataca gcggttgcct cagcagtgta tagaaaatac caggcgacta
     3721 ctggagatgc gactaagaca gtgattgctt caacagctag tccctacaag ttcccagtag
     3781 ttgcagtaga agcgctaaca gggaaagttg gcttgactga ttttgaagct ttggctcaat
     3841 tacatgaaat ctcaggcgtt gcagtgccac cagcagttga tgggcttgag acagctcctg
     3901 ttcgtcacaa gacaatagtg gcagctgctg acatgcaagt agcggttgag gcttatttag
     3961 gactttaaga tagagggagt aaactcggtt gggaaaccaa ctgagtttct tttcatcagg
     4021 aggagagatt gtttaagaaa aataaagaca ttcttaatat tgcattgcca gctatgggtg
     4081 aaaacttttt gcagatgcta atgggaatgg tggacagtta tttggttgct catttaggat
     4141 tgatagctat ttcaggggtt tcagtagctg gtaatattat caccatttat caggcgattt
     4201 tcatcgctct gggagctgct atttccagtg ttatttcaaa aagcataggg cagaaagacc
     4261 agtcgaagtt ggcctatcat gtgactgagg cgttgaagat taccttacta ttaagtttcc
     4321 ttttaggatt tttgtccatc ttcgctggga aagagatgat aggacttttg gggacggaga
     4381 gggatgtagc tgagagtggt ggactgtatc tatctctggt aggcggatcg attgttctct
     4441 taggtttaat gactagtcta ggagccttga ttcgtgcaac gcataatcca cgtctgcctc
     4501 tctatgttag ttttttatcc aatgccttga atattctttt ttcaagtcta gctatttttg
     4561 ttctggatat ggggatagct ggtgttgctt gggggacaat tgtgtctcgt ttggttggtc
     4621 ttgtgatttt gtggtcacaa ttaaaactgc cttatgggaa gccaactttt ggtttagata
     4681 aggaactgtt gaccttggct ttaccagcag ctggagagcg acttatgatg agggctggag
     4741 atgtagtgat cattgccttg gtcgtttctt ttgggacgga gacagttgct gggaatgcaa
     4801 tcggagaagt cttgacccag tttaactata tgcctgcctt tggcgtcgct acggcaacgg
     4861 tcatgctgtt ggcccgagca gttggagagg atgattggaa aagagttgct agtttgagta
     4921 aacaaacctt ttggctttct ctgttcctca tgttgcccct gtcctttagt atatatgtct
     4981 tgggtgtacc attaactcat ctctatacga ctgattctct agcggtggag gctagtgttc
     5041 tagtgacact gttttcacta cttgggaccc ctatgacgac aggaacagtc atctatacgg
     5101 cagtctggca gggattagga aatgcacgcc tcccttttta tgcgacaagt ataggcatgt
     5161 ggtgtatccg cattgggaca ggatatctga tggggattgt gcttggttgg ggcttgcctg
     5221 gtatttgggc agggtctctc ttggataatg gttttcgctg gttatttcta cgctatcgtt
     5281 accagcgcta tatgaacttg aaaggatagg aaatgcaaaa aacagctttt atttgggatt
     5341 tagacgggac tttattggac tcttacgaag cgattttatc agggattgag gagacttttg
     5401 ctcagttttc tattccttat gataaggaga aggtgagaga gtttatcttc aagtattcgg
     5461 tgcaagattt gcttgtgcgg gtggcagaag atagaaatct ggatgttgag gtgctaaatc
     5521 aggtgcgtgc ccagagtctg gctgagaaga atgctcaggt agttttgatg ccaggtgcgc
     5581 gtgaggtgct agcttgggca gacgaatcag gaattcagca gtttatatat actcataagg
     5641 ggaacaacgc ttttaccatt ctcaaggact tgggggtgga atcctatttt acagagattt
     5701 taaccagtca gagtggcttt gtgcggaagc caagtccaga agcggctacc tatctgctag
     5761 ataagtatca gttgaattct gataatactt attatatagg ggatcggact ctggatgtgg
     5821 aatttgccca gaatagtggg attcaaagca tcaacttttt agagtctact tatgaaggga
     5881 atcacaggat tcaagcgtta gcagatattt cccgtatttt tgagactaag tgataaaaag
     5941 attgtgtcag ttttgtgaca gagacctaac aaactatttc aagtaaccta gtttgttaca
     6001 aggaatagac agttctgtta aataggcccg agagggcttt ttttctacat tttttgtgtt
     6061 atgatagaca ggtactcatt tgaaaggaat ttgaaagaat gaagaaaaga atgttattag
     6121 cgtcaacagt agccttgtca tttgccccag tattggcaac tcaagcagaa gaagttcttt
     6181 ggactgcacg tagtgttgag caaatccaaa acgatttgac taaaacggac aacaaaacaa
     6241 gttataccgt acagtatggt gatactttga gcaccattgc agaagccttg ggtgtagatg
     6301 tcacagtgct tgcgaatctg aacaaaatca ctaatatgga cttgattttc ccagaaactg
     6361 ttttgacaac gactgtcaat gaagcagaag aagtaacaga agttgaaatc caaacacctc
     6421 aagcagactc tagtgaagaa gtgacaactg cgacagcaga tttgaccact aatcaagtga
     6481 ccgttgatga tcaaactgtt caggttgcag acctttctca accaattgca gaagttacaa
     6541 agacagtgat tgcttctgaa gaagtggcac catctacggg cacttctgtc ccagaggagc
     6601 aaacgaccga aacaactcgc ccagttgaag aagcaactcc tcaggaaacg actccagctg
     6661 agaagcagga aacacaagca agccctcaag ctgcatcagc agtggaagca actacaacaa
     6721 gttcagaagc aaaagaagta gcatcatcaa atggagctac agcagcagtt tctacttatc
     6781 aatcagaaga aacgaaagta atttcaacaa cttacgaggc tccagctgcg cccgattatg
     6841 ctggacttgc agtagcaaaa tctgaaaatg caggtcttca accacaaaca gctgccttta
     6901 aagaagaaat tgctaacttg tttggcatta catcctttag tggttatcgt ccaggagaca
     6961 gtggagatca cggaaaaggt ttggctatcg actttatggt accagaacgt tcagaattag
     7021 gggataagat tgcggaatat gctattcaaa atatggccag ccgtggcatt agttacatca
     7081 tctggaaaca acgtttctat gctccattcg atagcaaata tgggccagct aacacttgga
     7141 acccaatgcc agaccgtggt agtgtgacag aaaatcacta tgatcacgtt cacgtttcaa
     7201 tgaatggata aacccgactt gataacatca ttttgacgaa tgagatctag ctttcgtgat
     7261 ggaaagcgat tctcgttcgt tttttctttg tcatactctt cgaaaatctc ttcaaaccac
     7321 gtcagtttta tctgaaacct caaagctgtg ctttgagcaa cctgctacta gcttcctagt
     7381 ttgctttttg attttcattg agtatcaatt tgaatggaaa atggaaagtt atcatcttgt
     7441 aatgagttaa gcaacattct tgcaatctat tttactttat atcacaatta attagtcaaa
     7501 tattgataaa tcaataaaaa gagaggggaa gaaatgctag agattcaaga tttactgtat
     7561 caactccgct tgtctgagca agcgagtacg caattgtttg aaaaaaggct tgggattagt
     7621 ttgacacggt atcagatttt actgtttttg ctggagcatt ctccttgtaa ccaaatggcg
     7681 gttcaggagc gtttgaaaat tgatcaggct gctttgacac ggcatttcaa gattttggaa
     7741 acggaaggtt tggtggagcg tcatcgtaat cctgaaaatc agcgggaagt gttggtagag
     7801 gctgcgaagt atgccaagga gcagttagtg gtgaatcccc ctctgcaaca tatcaaggtt
     7861 aaggaagaga tggaaagtat cttaacagag tttgagagaa cagaactcag ccgtttatta
     7921 aataaattgg ttttgggtat tgaaaatata gaaatttaag tagaaataga tgtcaattat
     7981 tacaattatt ttaacaacga tcgttgcttt ggagcatttt tacatttttt atttggaaag
     8041 tattgccacg caatcagatg cgactagtcg tgtatttaat atggaaaagg aagaattggc
     8101 tcatccgtca gtaagttcat tgttcaaaaa tcaaggaatt tataaggctc tgctaggagt
     8161 ctttctcttg tatggcattt atttctcaca gaatttagaa attgtgacta tttttgtctt
     8221 atttgtgatt ggtgctgcga cttacggctc tttaacagcg gataaaaaaa ttattttgaa
     8281 acaaggtgga tcagctattt tggccttgat tagtatttta ctctttaaat acacttgaag
     8341 gtcgattcta atctcgctaa tcctttttaa tccagaataa gggaaatatg ttatacttgt
     8401 ttttaagaaa aaagtctcat tgaattggtt ttgaggagtt agaaatgaaa gtattagtga
     8461 caggttttga gccctttgga ggggaaaagg gcaatccagc tttggaggcc attaaaggtt
     8521 taccagctga aatccatggt gctgaggtcc gttggctaga ggtgccgaca gtttttcaca
     8581 aatctgctca agtattggaa gaagagatga atcgttatca acctgacttt gtcctttgta
     8641 ttgggcaagc tggtggaaga actagtttga cacctgaatg agtggccatt aatcaagacg
     8701 atgcacgcat ttctgataac gaagataatc aaccgattga ccgtcccatt cgcccagatg
     8761 gtgcttcggc ctactttagt agtttgccga ttaaagcgat ggttcaagct ataaaaaaga
     8821 aggattaccg gcctctgttt ccaatacggc agggactttt gtctgcagcc atttgatgta
     8881 tcaggctctc tatttggtag aaaagaaatt tccatatgtt aaggcaggtt ttatgcatat
     8941 tccttatatg atggaacagg tggtgaacag accgactact ccaactatga gtttagtgga
     9001 tattcggcga gggatagaag cagcaatcgg cgctatgata gaacatggag attaggaact
     9061 caagttggta ggcggagaaa ctcattgata gaaaaaagct tgaggggaaa aaccttcaag
     9121 cttttggacg ttttcgagcc aatactgctt ggtaaaacat aattttagtg cattggatat
     9181 aaggtaggag tgaaaaacta gcaatgccaa aggtaatcca attgaggaag taccaaggaa
     9241 gaagctgtaa atctaggaca aagtgctgga acttgtagcc cttcataaag gaacggctag
     9301 tttttaggat tcgtcttggt gggacctgtc ctaggtctag actataacag agaagaaatt
     9361 ccacctgtga ataggcataa tactgtggaa tatagaggat attccctaca atgatcaaga
     9421 tgagacttgc aagaaagtag agtccaaaga ccatgaggaa acgctcggtt tcaactgatg
     9481 agagatctag atttggaaac tcaggatgta gggtgacgaa ttttttggct aaaaagctac
     9541 tataaaagag gaggtaaatc ccaagtaaat tagggatact ccataaaaag agatagaaac
     9601 gtttgagaag tagggtcaaa aaggtttgag aaaagcgctc ctcatcaaag agagctaggc
     9661 tgttttttac agatggctcc gttttagaat ctttcatgag tgtcagtgtt gcatagacgg
     9721 aactggtcaa aagaatagtc ccgataaagg agactagtag aggaaagagg tatgcttgaa
     9781 gtatttggcc aagtatgctg aaaaatggct gttctaaaac agtcccgtgg atccgagata
     9841 agggattaag aaaactagat aagatgacca gcatactggg aaggatatag aggagaaaga
     9901 gacggggggt gtcagcctga aaatgttttg actcctgacg aattgttttt aaatcaattt
     9961 ttggatagtt cattctctta ttataccata gttcttatac atagttcgtg acagttccta
    10021 ctttttttga taaaatcata cagtgtgtcc ttgggcacac tgtatgaact gggactgtct
    10081 ttcccagctt cggaggtaaa aaatgtcaga ttcaccaatc aaatatcgtt tgattaagaa
    10141 agaaaaacac acaggagctc gtctaggaga aatcatcact ccccacggta cctttccgac
    10201 acctatgttt atgccagttg ggacacaagc cactgtcaaa actcagtcac ctgaagaatt
    10261 gaaggagatg ggttcgggaa ttatcctatc aaacacctat catctctggc ttcgccctgg
    10321 agatgaactc attgcacgcg ctggtggtct ccacaagttc atgaattggg accagcctat
    10381 cttgacagat agtggtggtt ttcaggttta ttctttagca gatagccgta atatcacaga
    10441 agaaggagta acctttaaaa atcatctaaa tggttctaag atgttcctat ccccagaaaa
    10501 agccatctct attcagaata atctgggttc agacatcatg atgtcctttg atgaatgtcc
    10561 tcagttttat caaccttatg actacgttaa gaaatcgatc gagcgtacca gccgttgggc
    10621 tgagcgtggt ttgaaggctc accgtcgtcc acatgaccaa ggtttgtttg gaattgtgca
    10681 aggtgcagga tttgaagacc ttcgccgcca atcagctcat gatcttgtca gcatggattt
    10741 ctcaggctac tctatcggtg gtttggcagt gggagaaacg catgaagaga tgaatgcggt
    10801 cttggacttt acaactcaac tgctacctga aaataaacct cgttatctga tgggtgtggg
    10861 agcgccagat agcttgatcg atggggtcat tcgtggggtg gatatgtttg actgtgtctt
    10921 accgactcga attgctcgta acgggacttg tatgaccagt caaggacgtt tggttgtgaa
    10981 aaatgcccag tttgctgagg actttacgcc actggatcct gagtgtgact gctacacatg
    11041 taataactat acacgcgctt accttcgtca cctgctcaag gctgatgaaa cctttggtat
    11101 ccgcttgact agctaccaca atctttactt cttgcttaac ctgatgaagc aagtgcgaca
    11161 agccatcatg gatgacaatc tcttggaatt ccgtgagtat tttgtggaaa aatatggcta
    11221 taataagtca ggacgtaatt tctaaaatgg aattgatata aaaaaatcct aagttttctc
    11281 ttaggatttt tcttcttttt ttgatagaat aaagtgtaca atgaaaggaa gaataaactc
    11341 gtatgcgcat taaatggttt tccttgatta ggattacagg tttacttttg gtactcttgt
    11401 atcacttctt tcagacgatc tttcctggag gatttttcgg ggtagatgtc tttttcacat
    11461 tttcaggttt cctgattaca gctctactca ttgaagaatt ttctaaaaac catgagattg
    11521 atttgatagg attttttaga agacgctttt atcggattgt gccacctgtg gttttgatgg
    11581 tcttggtgac catgcctttt actttcttgg ttcgccaaga ctatgttgct ggaattggtg
    11641 gccagattgc gggcgtctta ggctttatga ccaacttcta tgaactccta acaggtggga
    11701 gttatgaatc tcagttcatt cctcatttgt ttgttcataa ttggagtttg gcagttgagg
    11761 ttcattacta tattctttgg ggattggcag tttggttctt atccaaacaa gctaaatcaa
    11821 atggtcagtt gaaggggatg gtctttctct tatctgctgt tgccttcttg atcagtttct
    11881 tctccatgtt tattggtagt tttctagtga cctcttattc ctctgtttat ttctccagtt
    11941 taactcatgt ctatccattc tttttgggaa gtatgttagc aactattgta ggcgttcgtc
    12001 agacgacttc cctcgtcaag cagttggata aaatctggga tttacgaaag actttggtag
    12061 tttttggagg aggctttggt ttcctagttc ttttgacttt ctttgtcaaa ttcacttatc
    12121 tttttgccta tcttatcggc ttcttacttg ccagtcttgc agctcttgcc atgattctgg
    12181 cggcgcgtgt cttacatgaa aagacacatc atatacagga gccgaagatt atcagctttt
    12241 tagcggatac tagctatgcg gtttatcttt tccattggcc tttctatatc attttctcac
    12301 agttgacatc aaatcttctt gctgtattac tgactctgat ttgttcttat ggctttgcca
    12361 gtctgtcatt ctatgtattg gaaccttgga ttgcaggcaa gaacacacct attgtccaaa
    12421 cccttcgtcc cctgccttat attcacgcaa ttcttgcagc aggtacagga atcttgacca
    12481 tcattgtctg cacggtgacc ttgttggcac cacaagtggg agcgtttgag acagacttga
    12541 ctgtcaatgg cttgaagcaa gctgcaacaa atattggcca gaccaaggtg atggcagaac
    12601 gggcagatgc aaacagtttg ggaattgctg atggcactat gttaattggt gactcagtgg
    12661 ctttaagggc aaatacagca ctacagacag ctcttcctgg agcacagatt aacgcgcagg
    12721 tcagcgtaac aaccaagacc gcaaatgaaa tcatgctaaa taatagccag aataaatttt
    12781 tacctaagac ggtggtcatt gcgactgggg taaataatcc tgagaattac aaggatgact
    12841 gggacagtat cgtgaaaaat cttcctaagg gacaccatat gattttggtg actccttatg
    12901 agggagataa gacaaaagag acctatgcca tcgttgagaa ggctgctgcc tatatgagag
    12961 aattggcaga gaagacacct tacattacga tagcagattg gaatcaagtt gcgaaagagc
    13021 atccagaaat ttgggctgga acagaccagg ttcatttcgg gagtgagagt agcactatcg
    13081 aagcaggagc aaaattgtat gcagatacga ttgccacagc tttgcagaca gctcaagaca
    13141 agccggttaa atcaaaataa cttgtattaa aaaagagaag agttggagaa atccagctct
    13201 tttaaaatat ctccaaaaaa taggtctata ccatttacaa ataaaaaaga aaggtttata
    13261 atgtaattga cataataaat tgtagaatca atcttttaag gaggttaaca ttatgcctaa
    13321 ctatattaaa gcggatcagt ttttctaccc acacggagtt cgtcgaggtg gttacttgga
    13381 acttgtggac ggcaagtttg ggaaacatgt agagcagatt cctgaagggg ctgaggtgat
    13441 tgactataca ggttatagca ttgccccagg tcttgtggat actcatattc atggatatgc
    13501 aggtgtagat gtgatggaca acaacattga aggtacattg catactatga gtgaaggact
    13561 tcttagtacc ggtgttacca gtttcttacc cacaacttta acagccactt atgagcaatt
    13621 gcttgcagtc actgaaaatc ttggaaacca ttataaagaa gcaacaggtg ctaagattcg
    13681 tgggatttat tatgaaggtc catatttcac agaaactttt aagggggcac aaaatccaac
    13741 ttatatgaga gacccgggtg ttgaggagtt tcattcttgg caaaaagcgg caaatggctt
    13801 gcttaataaa attgcccttg caccagaacg tgatggggtg gaagactttg ttcgtacagt
    13861 tacgggcgaa ggtgtgacgg ttgctcttgg acattcaaac gcgacttttg atgaagccaa
    13921 aaaagcagtc gatgctggag cgagtgtttg ggtgcatgcc tacaatggaa tgcgtgggtt
    13981 gactcaccgt gaattgggta tggttggagc catgtaccaa ttgccacata cctatgcaga
    14041 gttgatctgt gatggtcacc acgtagaacc aaaggcttgc gaaattctta tcaaacaaaa
    14101 aggaacagaa aacatcgctc ttatcacaga ctgtatgaca gctgggggat tggaagacgg
    14161 agattatatg ttgggagaat tcccagttgt cgttgcaaat ggaactgcac gcctcaaatc
    14221 gacaggtaac ttggcaggtt ctatcctcaa actcaaagat ggtttgaaga atgtggtcga
    14281 atggggaatt gcgaatccgc atgaagcagt catgatggcc agcttcaacc cagctaaatc
    14341 cgttcacatc gatgacgtct gtggccaaat ccgtgaaggc tacgacgctg acttcatcgt
    14401 attagataaa gatttggaat tggtagcaac ctacctagat ggcgtaaaac gttatcaagc
    14461 ataagagaga aagcagaagt tagagactaa cttctgcttt tttatacagg gtactttact
    14521 ggtaaataaa aagttaaaaa aatcacaaaa aaagcttgaa gaaacaaaga aaaaggctta
    14581 caattgaact ataaatatta caaataaaaa aacggaggag tgctttatga aagcctatac
    14641 ttatgttaaa ccaggacttg cttcttttgt tgatgtagac aaaccagtta ttcgcaagcc
    14701 aacagacgct attgtgcgta ttgtaaaaac cactatttgt ggaacagacc tccatattat
    14761 caaaggggat gttcctactt gccaaagtgg taccattctt ggccacgaag ggattgggat
    14821 tgttgaagaa gttggggaag gagtttccaa cttcaaaaaa ggtgacaagg tcttgatttc
    14881 ttgcgtctgt gcctgtggta aatgctacta ctgtaaaaaa ggaatttatg cccactgtga
    14941 agacgaaggg ggctggattt tcggtcactt gattgatggt atgcaggctg aatatctacg
    15001 tgtccctcat gcagataata ctctttacca tactccagaa gacttgtcag atgaagcttt
    15061 ggttatgctg tcagacattc tgcctactgg atatgaaatt ggtgtcttaa aagggaaagt
    15121 agaacctggt tgcagcgtag ccattattgg ttcaggtcca gttggattgg ctgctctttt
    15181 aacagcccaa ttctattcac cagctaaatt gattatggta gacctagacg ataaccgctt
    15241 ggaaactgcc ctatcattcg gtgcgactca taaggttaat tcttcagacc ctgaaaaagc
    15301 cattaaagaa atttatgatt tgacagatgg tcgtggtgtg gatgtcgcta tcgaagctgt
    15361 tggtattcct gcaacatttg atttctgtca aaagattatc ggtgtagacg gaacggttgc
    15421 caactgtggt gtgcatggta aaccagttga attcgattta gataaacttt ggattcgtaa
    15481 catcaatgta acaactggtt tggtatctac aaatacgact ccacaattgt tgaaagcact
    15541 tgaaagtcat aagattgaac cagaaaaatt ggtaactcac tatttcaaac tcagtgaaat
    15601 tgaaaaagcc tatgaagtct tcagtaaggc agcagaccac catgccatta aggtcattat
    15661 cgaaaacgat atctcagaag cctaagtagt aaaaatattt ttgtacataa gtaaatagaa
    15721 attcagtcat ccatcagatg gctgaatttt ttatcaaaaa attaagaaat gagcatattt
    15781 ctttccttgt ctggcggaat tggttataat atacggtaca aaggaatgaa tgaatatgta
    15841 tcgtgttata gaaatgtacg gagattttga accgtggtgg ttcttagaag gttgggaaga
    15901 agatattgta gcaagtagaa aatttgacca gtattatgat gctctcaaat actacaaaac
    15961 ttgctggttt agattggaac aagaatcccc tctttataaa agtagaagcg acttgatgac
    16021 cattttttgg gacccggaag accaacgctg gtgtgatgaa tgtgatgagt atttacaaca
    16081 ataccattct ttggcccttt tgcaggatga gcaggttatc ccagacgaaa aactacgctc
    16141 aggctatgaa aaacaaacca gtcaggaaag gaatcgttct tgccgtatga aattaaaata
    16201 gagaaaagta acttttttgg agttgctttt tttatttttc taactctttg cgaatagtat
    16261 aggtgaggag gtaagtatgg ttcaagaaat tgcacaagaa atcattcgtt cagctcggaa
    16321 aaaagggacg caggatattt attttgtccc taagttagac gcctatgagc ttcatatgag
    16381 ggtaggagac gagcgctgta aaattggtag ctatgatttt gaaaagtttg cagccgttat
    16441 cagtcacttt aagtttgtgg cgggtatgaa tgtgggagaa aaaagacgta gtcaactggg
    16501 ttcctgtgat tatgcctatg accagaagat ggcgtctcta cgtttatcta ctgtaggcga
    16561 ttatcggggg catgagagtt tggttatccg tttgttgcac gatgaggagc aggacttgca
    16621 tttttggttt caggatattg aagaattagg caagcagtac aggcaacggg gactctatct
    16681 ttttgctggc ccggttggga gtggtaagac gaccttgatg catgaattgt ccaagtcact
    16741 ctttaaagga cagcaagtta tgtccatcga agatcctgtc gaaatcaagc aggacgacat
    16801 gcttcagttg cagttgaacg aagcaatcgg cctaacctat gaaaatctaa tcaaactttc
    16861 cttgcgtcat cgaccagatc tcttgattat cggagaaatt cgtgacagcg agacggcgcg
    16921 tgcagtggtc agagctagtt tgacaggtgc gacagtcttt tcaaccattc acgccaagag
    16981 tatccgaggt gtttatgagc gtctgctgga gttgggtgtg agtgaagaag aattggcagt
    17041 tgttctgcaa ggagtctgct accagagatt aatcggggga ggaggaatcg ttgactttgc
    17101 aaacagagat tatcaagaac accaagcagc caagtggaat gagcaaattg accagcttct
    17161 taaagatgga catatcacaa gtcttcaggc tgagacggaa aaaattagct acagctaagc
    17221 aaaaaaatat catcacccta tttaacaatc tcttttctag cggttttcat ctggtggaga
    17281 ccatctcctt tttagatagg agttccttgt tggacaagca gtgtgtgacc cagatgcgta
    17341 caggtttgtc tcaggggaaa tcattctcag aaatgatgga aagtttggga tgttcaagta
    17401 ccattgtcac tcagttatct ctagctgaag ttcatggcaa tcttcacctg agtttgggaa
    17461 agatagaaga atatctagac aatctggcca aggtcaagaa aaagttaatt gaagtagcga
    17521 cctatccttt gattttgctg ggttttcttc tcttaattat gctggggcta cggaattacc
    17581 tgctcccaca actggatagt agcaatattg ccacccgaat tatcggtaat ctgccacaaa
    17641 tttttctagg catggtaggg cttgtttccg tgcttgccct tttagcacta actttttata
    17701 aaagaagttc taagatgagt gtcttttcta tcttagcacg ccttcccttt attggaatct
    17761 ttgtgcagac ctacttgaca gcctattatg cacgtgaatg ggggaatatg atttcacagg
    17821 gaatggagct gacgcagatt tttcaaatga tgcaggaaca aggttcccag ctctttaaag
    17881 aaatcggtca agatctggct caaaccctga aaaatggccg tgaattttct cagacgatag
    17941 gaacctatcc tttctttagg aaggaattga gtctcatcat agagtatggg gaagttaagt
    18001 ccaagctggg tagtgagttg gaaatctatg ctgaaaaaac ttgggaagcc ttttttaccc
    18061 gagtcaaccg caccatgaat ttggtgcagc cactggtttt tatctttgtg gcactgatta
    18121 tcgttttact ttatgcggca atgctcatgc ccatgtatca aaatatggag gtaaattttt
    18181 aaaatgaaaa aaatgatgac attcttgaaa aaagctaagg ttaaagcttt tacattgatt
    18241 gagatgttgg tggtcttgct gattatcagc gtgcttttct tgctctttgt acctaatctg
    18301 accaagcaaa aagaagcagt caatgacaaa ggaaaagcag ctgttgttaa ggtggtggaa
    18361 agccaggcag aactttatag cttagaaaag aatgaagatg ctagcctaag aaagttacaa
    18421 gcagatgggc gcatcacgga agaacaggtt aaagcttata atgaatacta tactaaaaat
    18481 ggaggggcaa atcgtaaagt caatgattaa ggcctttacc atgctggaaa gtctcttggt
    18541 tttgggactt gtgagtatcc ttgccttggg cttatccggc tctgtccagt ccacttttgc
    18601 agcagtagag gagcagattt tctttatgga gtttgaagaa ctctatcggg aaacccaaaa
    18661 acgcagtgta gccagtcagc aaaagactag tctaaattta gatgggcaga cgcttagcaa
    18721 tggcagtcaa aagttgacag ttcctaaagg aattcaggca ccatcaggcc aaagtattac
    18781 atttgaccga gctgggggca attcgtccct ggctaaggtt gaatttcaga ccagtaaagg
    18841 agcgattcgc tatcaattat atctaggaaa tggaaaaatt aaacgcatta aggaaacaaa
    18901 aaattagggc agtgatttta ctggaagcag tagtcgctct agctatcttt gccagcattg
    18961 cgaccctcct tttgggacaa attcaaaaaa ataggcaaga ggaagcaaaa atcttgcaaa
    19021 aggaagaagt cttgagggta gctaagatgg ccttgcagac aggtcaaaat caggtaagca
    19081 tcaacggagt tgagattcag gtattttcta gtgaaaaagg attggaggtc taccatggtt
    19141 cagaacagtt gttggcaatc aaagagccat aaggtcaagg cttttacctt gttagaatcc
    19201 ctgcttgccc tgattgtcat cagtggggga ttactccttt ttcaagctat gagtcagctc
    19261 ctcatttcag aagttcgcta ccagcaacaa agcgagcaaa aggagtggct cttgtttgtg
    19321 gaccaacttg aggcagaatt agaccgttcg cagttcgaaa aagtagaagg caatcgccta
    19381 tacatgaagc aagatggcaa ggagattgct atgggtaagt ctaaggcaga tgatttccgt
    19441 aaaacgaatg ctcgtggtcg aggttatcag cctatggttt atggcctcaa atcagctcag
    19501 attacagagg acaatcaact ggttcatttt cgtttccagt ttcaaaaagg cttagaaagg
    19561 gagttcatct atcgtgtgga aaaagaagaa agttaaggca ggtgttctcc tctatgcagt
    19621 caccatggca gctatcttta gtcttttgtt gcaattttac ttgaaccgac aagtcgccca
    19681 ctatcaagac tatgctttga ataaagaaaa attggttgct tttgctatgg ctaaacgaac
    19741 caaggataaa gccgagcaag aaagtgggga acaggtcttt aatctaggtc aggtaagcta
    19801 tcaaaacaag aaaacaagct tggtgacgac tgttcgtacg tctaagagcc aatatgagtt
    19861 tctgtttcct tcagtcaaaa tcaaagaaga gaaaagagat aaaaaggaag aggtagcgac
    19921 cgattcaagc gaaaaagtgg agaagaaaaa aatcagaaga gaagcctgaa aagaaagaga
    19981 attcctagtc aattcaacta taatgcgttg aatccagaat agtccactgt agtttctaga
    20041 aaattgctgg aaatggatgt taagctccaa ttcatttgtt tatatcttat ttcagtttac
    20101 tatactttgt gctaaactaa agatatgaaa catgatttta accacaaagc agaaactttc
    20161 gactccccta aaaatatctt cctcgcaaac ttggtatgtc aagcagtcga gaaacagatt
    20221 gatattttat cagacaaagt aattttagat ttcggtggtg gcacgggtct attagccttg
    20281 cccctagcca agcaggctaa gtcagttact cttgtagaca tttctgagaa aatgttggag
    20341 caagctcgtt tgaaagcgga gcagcaagca atcaagaata tccagttttt ggagcaagat
    20401 ttaccgaaaa atcccttgga gaaagagttt gattgccttg ctgttagtcg ggttcttcat
    20461 catatgcctg atttggatgc ggctctctca ctgtttcatc aacatttgaa ggaagatggg
    20521 aaactcatca ttgctgattt taccaagaca gaagctaatc atcatggatt tgatttagct
    20581 gaactggaaa acaagctaat tgagcatggt ttttcatctg tgaatagtca gattctctat
    20641 agcgctgaag acctgtttca agggaatcac tcagaattct ttttaacagt atcccaaaaa
    20701 tcactcgcct agtcagggag tgatttttct ataaggatgg aaaaaagaag ggaaatttga
    20761 taagatagga atatggattt tgaaaaaatt gaacaagctt atatctattt actagagaat
    20821 gtccaagtca tccaaagtga tttggcgacc aacttttatg acgccttggt ggagcaaaat
    20881 agcatctatc tggatggtga aactgagcta aaccaggtca aagacaacaa tcaggccctt
    20941 aagcgtttag cactacgcaa agaagaatgg ctcaagacct accagtttct cttgatgaag
    21001 gctgggcaaa cagaaccctt gcaggccaat caccagttta caccggatgc tattgctttg
    21061 cttttggtgt ttattgtgga agagttgttt aaagaggagg aaattactat cctcgaaatg
    21121 ggttctggga tgggaattct aggcgctatt ttcttgacct cgcttgataa aaaggtggat
    21181 tacttgggaa tggaagtgga tgatttgctg attgatctgg cagctagcat ggcagatgta
    21241 attggtttgc aggctggctt tgtccaagga gatgccgttc gcccacaaat gctcaaagaa
    21301 agcgatgtgg tcatcagtga cttgcctgtc ggctattatc ctgatgatgc cgttgcgtcg
    21361 cgccatcaag ttgcttctag ccaagaacat acttacgccc atcacttgct catggaacaa
    21421 gggcttaagt acctcaagtc agacggatac gctatttttc tagctccgag tgatttgttg
    21481 accagtcctc aaagtgattt gttaaaagaa tggctgaaag aagaggcgag tctggttgct
    21541 atgattagtc tgcctgaaaa tctctttgct aatgccaaac aatctaagac tatttttatc
    21601 ctacagaaga aaaatgaaat agcagtagag ccttttgttt atccacttgc tagcttgcaa
    21661 gatgcaagtg ttttaatgaa atttaaagaa aattttcaaa aatggactca aggtactgaa
    21721 atataaaata gattttgtta taatagttga aaacgcttaa aaaggggtat catgttatga
    21781 caaaaacaat tgcaatcaat gcaggaagtt caagtttgaa atggcaatta tacttaatgc
    21841 cagaggaaaa agtgttagcc aaaggtttga ttgaacgtat cggtttgaaa gattcaattt
    21901 caactgtaaa atttgacggc cgttctgaac aacaaatttt ggatatcgaa aatcatatac
    21961 aagccgttaa aattttattg gatgacttga ttcgtttcga tattatcaag gcttatgacg
    22021 agattacagg tgttggacat cgtgttgttg ctggtggaga atatttcaaa gaatcaacag
    22081 ttgttgaggg agatgtttta gaaaaagttg aagagttgag tttgttggct cctctacaca
    22141 acccggccaa tgcagcaggt gttcgtgcct tcaaggaatt gttgccagac attaccagtg
    22201 tagttgtttt tgatacttcc ttccacacaa gtatgccaga gaaagcttat cgctaccctc
    22261 taccaacaaa atattacaca gaaaacaagg ttcgtaaata cggtgctcat ggtacaagtc
    22321 accagtttgt agcaggagaa gctgcaaaac tcttgggacg tccattagaa gacttgaagt
    22381 taattacctg tcatattggt aacggaggct caattacagc tgtgaaagcc ggcaaatctg
    22441 tagacacttc tatggggttc actcctcttg gtggtattat gatgggaacg cgtacagggg
    22501 atattgatcc agctatcatt ccttatttaa tgcaatatac agaggatttt aacacaccag
    22561 aagatatcag tcgtgttctt aaccgtgaat caggtctttt gggagtttct gctaattcta
    22621 gcgatatgcg cgatatagaa gcagctgtag cagaagggaa tcacgaggct agcttggctt
    22681 atgaaatgta tgttgaccgt atccaaaaac atatcggtca gtaccttgca gtgctaaatg
    22741 gagcagatgc cattgttttc acagcaggtg tcggtgaaaa tgcagagagt ttccgtcgtg
    22801 atgtaatctc agggatttcg tggtttggtt gtgatgttga tgatgaaaag aatgtctttg
    22861 gcgttacagg agacatctca acagaggcag ctaaaatccg tgtcttggtt attccaacag
    22921 atgaagaatt agtcattgcc cgtgacgttg aacgcttgaa aaaataagtg aaactaaaaa
    22981 atattcaata caaggagttg ggaaagttat ttttccagct tctttttctg atgaaattgt
    23041 ccaaaacctt gctatgattg gcttttttga aaaatatggt ataatagtag taatttaata
    23101 gatggagttt agttttgaag aaaaactttc gtgtaaaaag agagaaagat tttaaggcga
    23161 ttttcaagga ggggacaagt tttgctaatc gcaaatttgt ggtctaccaa ttagaaaacc
    23221 agaaaaacca ttttcgagta ggtctatcag ttagcaaaaa actggggaat gccgtcacta
    23281 gaaatcaaat taagcgacgg attcggcata ttatccagaa tgcaaaaggg agtctggtag
    23341 aagatgtcga ctttgttgtc attgctcgaa aaggagtcga aaccttggga tacgcagaga
    23401 tggagaaaaa tctactccat gtattaaaat tatcaaagat ttaccgggaa ggaaatggga
    23461 gtgaaaaaga aactaaagtt gactagtttg ctaggactgt ctctgttaat catgacagcc
    23521 tgtgcgacta atggggtaac tagcgatatt acagccgaat cggctgattt ttggagtaaa
    23581 ttggtttact tctttgcgga aatcattcgc tttttatcgt ttgatattag tatcggagtg
    23641 gggattattc tctttacggt cttgattcgt acagtcctct tgccagtctt tcaggtgcaa
    23701 atggtggctt ctaggaaaat gcaggaagct cagccacgca ttaaggcgct tcgagaacaa
    23761 tatccaggtc gagatatgga aagcagaacc aaactagagc aggaaatgcg taaagtattt
    23821 aaagaaatgg gtgtcagaca gtcagactct ctttggccga ttttgattca gatgccggtt
    23881 attttggccc tgttccaagc cctatcaaga gttgactttt taaagacagg tcatttctta
    23941 tggattaacc ttggtagtgt ggatacaacc cttgttcttc cgattttagc agcagtattc
    24001 acctttttaa gtacttggtt gtccaacaaa gctttgtctg agcgaaatgg cgctacgact
    24061 gcgatgatgt atgggattcc agtcttgatt tttatctttg cagtttatgc gccaggtgga
    24121 gtcgccctat actggacagt gtctaatgct tatcaagtct tgcaaaccta tttcttgaat
    24181 aatccattca agattatcgc agagcgcgag gccgtagtac aggcacaaaa agatttggaa
    24241 aatagaaaaa gaaaagccaa gaaaaaggct cagaaaacga aataaataag gaggaatctg
    24301 gtaatggtag tatttacagg ttcaactgtt gaagaagcaa tccagaaagg attgaaagaa
    24361 ttagatattc caagaatgaa ggctcatatc aaagtcattt ctagggagaa aaaaggcttt
    24421 cttggtctat ttggtaaaaa accagcccaa gtggatattg aagcgattag tgaaacgact
    24481 gttgtcaaag caaatcaaca ggtagtaaaa ggcgttccga aaaaaatcaa tgatttgaac
    24541 gagcctgtga agacggttag tgaagaaacc gttgaccttg gtcatgtggt taatgctatt
    24601 aaaaaaatag aggaagaagg tcaaggtatt tctgatgaag tcaaggctga aatcttaaaa
    24661 catgaaagac atgccagcac tatcttagaa gaaactggtc acattgagat tttaaatgaa
    24721 cttcaaatcg aggaagcgat gagggaagaa gcaggcgctg atgaccttga aactgagcaa
    24781 gatcaaactg aaaatcaaga cttgaaagag atgggcttga aggtcgagca aagttatgat
    24841 attgcccagg tggctacgga tgtgactgcc tatgttcaag cgattgtgga tgacatggat
    24901 gttgaggcta cactttcaaa tgattataac cgtcgtagca tcaatctaca aattgacacc
    24961 aacgaaccag gtcgtattat cggctaccat ggtaaagtct tgaaggcctt gcaactgttg
    25021 gctcaaaatt atctttacaa ccgctattcc aaaaccttct acgttacaat caatgtcaat
    25081 gattatgtcg aacaccgtgc agaagtcttg cagacctatg cgcaaaaatt ggcgaatcgt
    25141 gttttggaag aaggtcgcag tcataaaaca gatccaatgt caaatagcga acgcaagatt
    25201 atccatcgta ttatttcacg tatggatggc gtgactagtt actctgaagg tgatgagcca
    25261 aatcgctatg ttgttgtaga tacagaataa gtaaaatcag ggttgacctg attttttgct
    25321 agttagagga ggttaaactg atgttgaata agataagaga ctatctagac ttttctggtt
    25381 tgcagtaccg tagtcctgat aaagcgggag cagagcgaga gaagatgctg gcgttccgcc
    25441 acaaaggaca agaggcccga aaggctttta cagaactggc caaagccttt caagcaagcc
    25501 atccagaatg gcaactccaa cagactagtc agtggatgaa tcaggcccag cgtttgagac
    25561 cacatttttg ggtttatcta cagagagacg gacaagtgac agaacctatg atggccttac
    25621 gtttgtatgg gacatctact gactttggaa tttctttgga agtcagtttc atcgaacgta
    25681 agaaggatga gcaaacactg ggcaagcaga ccaaagtttt agacattcca accgttaaag
    25741 ggatttatta tctaacctac tctaatggtc aaagtcaacg gtgggaggcg aatgaagaaa
    25801 agcgtcgtac tttacgcgag aaggtgagaa gtcaagaagt tcgaaaagtt ttagtgaagg
    25861 tagatgttcc tatgacagaa aattcgtctg aagaagaaat cgtagaaggc ttattgaagt
    25921 cttattctaa aattcttccc tattatctag ctacgagaaa ataatataat ttgtaaaaca
    25981 tcataaatca tacagtccaa gagtgaacag tccgctgtgt aattcttggt ctttttgttt
    26041 gcgctttcgc attatataat aaacttacaa aaacaattca aaaggagaac aattatggaa
    26101 gtcgtttcaa gtgttctaaa ttggttttct agcaatattt tgcagaatcc cgcatttttc
    26161 gtaggtttat tggtgttgat aggatatgca cttttgaaaa aacctgccca tgacgttttt
    26221 tcagggtttg ttaaagcaac agtagggtat atgttgctta acgtgggtgc tggtggtttg
    26281 gttacaacct ttcgtccaat cttagcagct cttaactaca aattccaaat tggtgcagcg
    26341 gttatcgacc cttactttgg acttgctgca gcaaacaaca aaattgcagc agagtttcca
    26401 gattttgttg gaactgcaac tacagctcta ttgattggtt tcggaataaa tatcttgctc
    26461 gtagctcttc gaaagattac gaaggtaaga accctcttta ttactggtca catcatggta
    26521 caacaagctg caacagtatc tcttatggtt ctattcttag taccacaatt gcgcaatgct
    26581 tacggtacag cagcgattgg tatcatctgt ggactttact gggcagttag ttcaaatatg
    26641 actgttgagg caactcaacg cttgactggt ggtggcggat ttgcgattgg tcaccaacag
    26701 caatttgcaa tctggtttgt agataaagta gcaggacgct ttggtaagaa agaagaaagt
    26761 ttagacaatc ttaaattacc taagttcctc tcaatcttcc acgatacagt tgttgcatct
    26821 gctaccttga tgctcgtatt cttcggagcc attcttttaa tcttgggtcc agacattatg
    26881 tctaataaag aagtcatcac ttcaggaact ctattcaatc ctgctaaaca agatttcttt
    26941 atgtacatta tccaaacagc ctttaccttc tcagtttact tgttcgtttt gatgcaaggt
    27001 gtccgaatgt tcgtatctga gttgacaaac gccttccaag gtatttcaaa caaattgttg
    27061 ccaggttcat tcccagcggt tgacgttgca gcttcttatg gatttggttc tccaaatgct
    27121 gtcttgtcag gatttacctt tggtttgatt ggtcaattga ttacaattgt tttgctcatc
    27181 gtctttaaaa atccgattct tattattaca ggatttgtac cagtgttctt tgacaatgca
    27241 gccattgcgg tctacgctga taaacgcggc ggatggaaag cggctgttat cctttccttt
    27301 atatcaggtg tccttcaagt tgctctagga gctctttgtg tggcccttct cgatttggca
    27361 tcttatggtg gctaccatgg aaatatcgac tttgaattcc catggcttgg atttggatat
    27421 atcttcaaat accttggtat tgttggttat gtacttgtgt gtctcttctt gcttgttatt
    27481 cctcaacttc aatttgccaa agcaaaagat aaagagaaat attacaacgg tgaagttcaa
    27541 gaagaagctt agtatctaga aaaggagaaa taaaatggtt aaagtattag cagcgtgcgg
    27601 aaatggaatg ggttcatcaa tggttatcaa gatgaaggtt gaaaatgctc tccgtaagct
    27661 taatcaaaca gattttacag tcaattcatg cagtgtcggt gaagctaaag gtttagcagt
    27721 aggatatgac atcgtaatcg cttctcttca tttgattcaa gaattggaag ggcgaactaa
    27781 tgggaagtta attgggcttg ataacttgat ggatgataaa gaaatcaccg aaaaactcag
    27841 tcaagcacta cagtaaaagg ttggaggggg ctggacagaa actgagagtt atcgtttctg
    27901 tccttctccc tctttaaata aaggaggcag atatgaattt aaaacaagct ttaattgaca
    27961 atgactcgat ccgactaggt ttagaggcta acaattggaa agaagcagtc aaggtagcag
    28021 tagatccctt aattgaaagt ggggcaattt tgccagagta ttacgatgct atcattgaat
    28081 cgactgaaga gtatgggcct tactatatct tgatgccagg tatggctatg ccccacgcta
    28141 gacctgaagc tggtgtgcaa agtgatgcct tttcattgat taccttacaa aatcctgttg
    28201 tattttcaga tgggaaagag gtatctgttt tgttggcact agcagcaaca agttcaaaaa
    28261 ttcacacaag tgtagccatt ccacaaatta ttgccctgtt tgaattagaa gattctattg
    28321 cacgtttaca ggcttgccag actaaagaag atgtcttggc tatgattgaa gaatctaagg
    28381 atagccctta tctcgaagga ttggatttgg aaagttagaa agaggaataa agaaatgaca
    28441 aaaagaatac ctaatttaca agttgcatta gaccattcag acttgcaagg agcgattaaa
    28501 gcagctgttt ctgttggtca ggaagtagat attatcgaag ctggaactgt ttgcttgctt
    28561 caagttggaa gtgaactggc tgaagtcttg cgtagccttt tcccagataa gattattgtg
    28621 gcagacacaa aatgtgctga tgctggtgga acagttgcta aaaataatgc ggttcgtgga
    28681 gcagactgga tgacttgtat ctgttgtgca accatcccta ctatggaagc agctctaaag
    28741 gctatcaaga ctgaacgagg agaacgaggc gaaatccaga tcgagcttta tggcgattgg
    28801 acttttgaac aagctcagct ttggctagat gcaggtatct cacaagctat ttatcaccaa
    28861 tctcgtgatg ctcttcttgc tggtgaaact tggggtgaaa aagaccttaa taaggttaaa
    28921 aaactcgttg acatgggctt ccgtgtatct gtaacaggtg gtctagatgt agatactctc
    28981 aaactctttg aaggtgttga tatctttacc tttatcgcag gtcgtggaat tacagaggct
    29041 gcggatccag caggagcagc gcgtgccttc aaggatgaaa tcaaacgaat ttgggggtaa
    29101 atcatggtac gtccaattgg aatttatgaa aaggcaaccc caacacactt tacttggcta
    29161 gaacgtttaa attttgccaa ggagttaggc tttgattttg tcgagatgtc tattgacgaa
    29221 cgtgacgagc gtttagcaag acttgactgg agtaaggaag aacgcttgga agttgtcaaa
    29281 gcaatctatg aaactggtgt tcgtattcct tctatctgtt tttcaggcca tcgtcgctac
    29341 ccattgggtt caaaagatcc agttctagag gaaaaatctc tagaactcat gaaaaaatgt
    29401 atcgaattag ctcaagactt gggagttcgt acgattcaat tagctggtta cgatgtttac
    29461 tatgaggaaa agtcacccca gacacgccaa cgttttatca aaaatttgag aaaagcctgt
    29521 gactgggctg aagaagctca ggtggtactt gctattgaaa ttatggatga tcctttcatc
    29581 agtagcatcg aaaaatattt ggctatagaa aaagagattg actctccctt cctctttgta
    29641 tatccagata ttggtaatgt gtctgcatgg cataatgata tctatagtga gttttatctt
    29701 ggtcatcatg ccatcgcagc tctccatctc aaggatactt atgcagtgac agaaagttca
    29761 aagggccagt tccgagatgt acctttcggg caaggttgtg tcaaatggga agaagctttc
    29821 gatattttaa aggaaaccaa ttataatgga cctttcctaa tcgaaatgtg gtctgaaaat
    29881 tgtgaaacag tagaagaaac acgcgccgcc gttcaagagg cgcaagcttt tctctatcca
    29941 ctcattaaga aagcaggttt gatgtaagat gaatcaagta atcaatgcta tgcgtaaacg
    30001 agtctgtgat gccaatcaat cattgccaaa acatggactt gtcaaattta cctgggggaa
    30061 tgtatctgaa gttaatcgcg aactcggtgt cattgttatc aaaccatcag gcgtggatta
    30121 tgacgaattg acacctgaaa acatggtagt gactgatcta gatggtaaga tcctagaagg
    30181 ggatttaaga ccatcttccg acctcccaac tcatgtgcaa ttatataagg cttggtcaga
    30241 aattggtagt gtggttcaca cccattcgac agaagctgtt ggttgggctc aggcaggtcg
    30301 tgatattcct ttctacggaa caacccatgc agattatttc tacggttcaa tcccttgcgc
    30361 ccgtagtttg accaaggacg aagtagaagt gacctatgaa aaagatactg gcctggttat
    30421 cgtagaagag tttgaacatc gcggacttaa cccggttgaa gtaccaggaa ttgttgtacg
    30481 caatcacggt ccattcacct ggggcaaaaa tccagagaat gctgtttatc actctgtcgt
    30541 actagaggaa gtatcaaaga tgaatcgctt tacagaacaa atcaatccaa gagttggacc
    30601 tgctccccag tacatactag aaaaacacta ccaacgtaaa catggaccaa atgcttatta
    30661 tggtcaaaag taagaacgat gaaggaggag aaaaagataa atttagctcc tctttttaca
    30721 tttgattttt attgagagta aagttggagt tgaagtaatt ttaaaagatt ttttagaaat
    30781 agcgcttgat atatatatgg taaaataaaa agaattgctg tgatatcaat agatttgggg
    30841 gattttttaa tatggtactg gataaggcaa gttgtgattt gcttcaatat ttgatggatc
    30901 aagaaacgtc caaaacgatt atggcgattt cgaaagattt gaaagagtca agaaggaaaa
    30961 tttattatca cattgacaaa atcaatgctg ctctgggtga cgaggcgctt cacatcatta
    31021 gtattccacg aattggtatt cacttaacgg aagagcagag agatgcttgt tgtaaactat
    31081 tatcggaagt agattgtacg attatatcat gagtgcgcat gaacgtatga tgataatgtt
    31141 actatggata ggtatttcta aagaacgtat tacgattgaa aaattgatag agttaacaga
    31201 ggtatctagg aatactgttc tcaatgattt gaatagtatt cgttatcaac taactttgga
    31261 acaatatcag gtgatcttgc aagtgagcaa gtcacaggga taccaccttc atgcccaccc
    31321 tcttaataaa attcagtatc ttcaatcgct tctatatcat atttttatgg aagaaaatgc
    31381 cacttttgta tctattttag aagataagat gaaagagagg ttagatgatg agtgtttgct
    31441 ttctgttgaa atgaaccaat tttttaagga acaggttcct ttagttgaac aagatttagg
    31501 gaagaaaata aaccatcatg aaataacttt tatgttgcag gttctacctt atttgctgtt
    31561 aagctgtcat aatgttgaac agtatcaaga aagacatcag gatatagagc aagaattttc
    31621 tttgataaga aaaagaatag agtatcaggt gtctaagaaa ttaggagaac ggttgtttca
    31681 aaagtttgaa atttctttgt caggacttga agtttctctt gtagctgttc tcctcctctc
    31741 ctatcgtaaa gatttggata ttcatgcaga aagtgatgat tttcggcaat taaaacttgc
    31801 tttagaagaa tttatctggt attttgaatc acaaatccga atggagattg agaacaagga
    31861 tgatttgtta cgaaatttga tgatccactg taaagccttg ttatttagaa agacttacgg
    31921 tattttttct aaaaatcctc taacaaaaca aattcgatcc aagtatggag aattattttt
    31981 agtcactaga aaatctgcgg aaattttaga aggagcatgg tttattcggc taacagacga
    32041 tgatattgcc tatttgacga ttcatattgg aggattttta aagtatacac catcgtctca
    32101 aaaaaatatg aaaaaagttt atctcgtttg tgatgaaggt gttgcggttt cgagactttt
    32161 gctgaaacaa tgcaaacttt attttccaaa tgagcaaatt gacactgtat ttacaacaga
    32221 acaatttaag agtgtggaag atattgcaca agttgatgta gtgattacta ctaatgatga
    32281 tttggatagc agatttccga ttttaagggt taatcctatc cttgaagcag aagatatttt
    32341 gaaaatgcta gactatctta aacacaatat atttcgtaat gagagcaaaa gtttcagtga
    32401 aaatctttct agtcttattt cgtcttatat tgtagacagc aagttggcta gtaagttcca
    32461 agaagaggtt caaacactta taaatcaaga aatagtagtt caagcttttt tggaagatat
    32521 ttgaaggaca gtccaatgat gaacacaaac ctgtgttttt cttggtcttt tttagtgttt
    32581 tgaagggtgg tatactaatc tcaaagataa caattatatc caaaggaggc aacatatgcc
    32641 aaacgtcaaa gaaattacaa gagagtcatg gattttagcc actttcccag agtggggaac
    32701 atggttgaac gaagaaatcg aagaagaagt cgtacctgaa ggcaactttg ccatgtggtg
    32761 gctaggcaac tgtggtactt ggattaagac accagctggt gctaacgttg tcatggacct
    32821 ttggtcaaac cgtggaaaat caaccaaaaa agtgaaagat atggttcgtg ggcaccaaat
    32881 ggcaaatatg gcaggtgttc gtaagctgca accaaacttg cgtgttcagc caatggttat
    32941 cgatccattt gctatcaacg aactagacta ttacttagtt tcacacttcc acagtgatca
    33001 tatcgaccca tacacagctg cagcaattct caacaatcct aagttagagc atgttaagtt
    33061 tatcggtcct taccactgtg gacgaatctg ggaaggatgg ggtgttccaa aagaacgtat
    33121 catcgttgtt aaaccaggtg acactatcga attaaaagat atgaagattc atgcagtaga
    33181 atcatttgac cgtacttgct tggtaactct cccagtgaac ggtgctgatg agacaggcgg
    33241 tgaacttgct ggcttggctg ttacagatga agaaatggct caaaaggctg ttaactatat
    33301 ctttgaaaca ccaggtggaa ccatctatca tggtgcagat tctcacttct caaactattt
    33361 tgcaaaacat ggtaaagact ttaaaattga tgttgctttg aataactatg gtgaaaatcc
    33421 ggtaggtatc caagacaaaa tgacatctat cgaccttctt cgtatggcag aaaatctgcg
    33481 taccaaagtc attatcccag ttcactatga tatctggtct aacttcatgg cttctactaa
    33541 tgagattcta gaactttgga aaatgcgaaa agatcgcttg caatacgatt tccatccatt
    33601 tatctgggaa gttggcggta agtacactta tcctcaagat caacacttag tagaatacca
    33661 tcatccacgt ggttttgatg attgttttga acaagactct aacattcaat ttaaagcttt
    33721 gctataatat aaaaatattc tttggaggtt atccgtatgt tgcatgatac ggataatttt
    33781 catataatag taaaatagaa tgtgtgattc aataatcacc tcaaatagaa aggaaattct
    33841 atgtcaaatc tatctgttaa tgcaattcgt tttctaggta ttgacgccat taataaagcc
    33901 aactcaggtc atccaggtgt ggttatggga gcggctccga tggcttacag cctctttaca
    33961 aaacaacttc atatcaatcc agctcaacca aattggatta accgcgaccg ctttattctt
    34021 tcagcaggtc atggttcaat gctcctttat gctcttcttc acctttctgg ttttgaagat
    34081 gtcagcatga atgagattaa gagcttccgt caatggggtt caaaaacacc aggtcaccca
    34141 gaatttggtc atacggcagg gattgatgct acgacaggtc ctctagggca agggatttca
    34201 actgctactg gttttgccca agcagaacgt ttcttggcag ccaaatataa ccgtgaaggc
    34261 tacaatatct ttgaccacta tacttacgtt atctgtggag acggagactt gatggaaggt
    34321 gtctcaagcg aggcagcttc atacgcaggt ttgcaaaaac ttgataagtt ggttgttctt
    34381 tatgattcaa atgatatcaa cttggatggt gagacaaagg attcctttac agaaagtgtt
    34441 cgtgaccgtt acaatgccta cggttggcat actgccttgg ttgaaaatgg aacagacttg
    34501 gaagccatcc atgctgctat cgaaacagca aaagcttcag gcaagccatc tttaattgaa
    34561 gtgaagacgg ttattggata tggttctcca aacaaacaag gaactaatgc tgtacacggc
    34621 gcccctcttg gagcagatga aactgcatca actcgccaag ccctcggttg ggactacgaa
    34681 ccatttgaaa ttccagaaca agtatatgct gatttcaaag aacatgttgc agaccgtggc
    34741 gcatcagctt atcaagcttg gactaaatta gttgcagatt ataaagaagc tcatccagaa
    34801 ctggctgcag aagtagaagc catcatcgac ggacgtgatc cagtcgaagt gactccagca
    34861 gacttcccag ctttagaaaa tggtttttct caagcaactc gtaattcaag tcaagatgcc
    34921 ttgaatgttg tggcagctaa attaccaacc ttcctaggtg gatcagctga ccttgctcac
    34981 tcaaacatga cttatatcaa gacggatgga cttcaagacg ataccaatcg cttgaatcgt
    35041 aacattcagt ttggtgttcg tgaatttgca atgggaacaa tcttgaacgg gatggccctt
    35101 catggtggac ttcgtgtata cggtggaact ttcttcgtct tctctgacta tgtgaaggca
    35161 gctgtccgct tgtcagcctt acaaggactt cctgtgactt atgtctttac ccatgattca
    35221 atcgcagttg gggaagatgg tccgactcac gaaccagttg agcatttagc aggtcttcgt
    35281 gctatgccaa atctaaatgt tttccgtcca gcagatgcgc gtgaaacgca agcagcttgg
    35341 taccttgcag tgacaagtga gaaaacacca actgcccttg tcttgacacg tcaaaacttg
    35401 actgttgaag atggaacaga cttcgacaag gttgctaaag gtgcttatgt tgtatatgaa
    35461 aatgcagccg actttgatac catcttgatt gcgacaggtt cagaggttaa tcttgctgtc
    35521 tcagctgcta aagaattggc tagtcaaggc gaaaaaatcc gcgtagtcag catgccatct
    35581 acagatgtct ttgataaaca agatgcagct tacaaggaag agattcttcc aaatgcagtc
    35641 cgccgtcgtg ttgcagtcga aatgggtgca agtcaaaact ggtacaaata tgttggtctc
    35701 gatggtgccg ttctaggtat tgataccttc ggagcctctg ccccagcacc aaaagtattg
    35761 gcagaatatg gctttactgt agaaaatctt gtaaaagttg ttcgaaactt gaaataatcc
    35821 taaaaatcag ggcgtaagct ctggtttttc ttaccagaaa agtaaggtac aatcttgtaa
    35881 aagtagctga aatttgatat agtagtccta tgtaaaagac aaaggagaag acaatgaatc
    35941 caaatattac ttttttaatc atgcttgtag gtatgatggc cttgatgttc tttatgcaac
    36001 gttctcaaaa gaaacaagct caaaagcgta tggaaagctt aaataaacta caaaaaggct
    36061 atgaagtgat tacaatcggt ggactttatg gaacagtcga tgaagtagat acggagaagg
    36121 gaacaatagt tcttgacgta gatggagttt acttgacttt tgaactaact gctatcaaga
    36181 cagtattacc gctgaaagaa acagcttcac tagaaggcgc aattgaaaaa taagacggga
    36241 tcacgaactc ccgtttttct ataaaagaaa ggaaatggga tgaaaaaatt agtctttgtc
    36301 tgtctgggaa atatttgccg tagccctatg gccgagtttg ttatgaaatc aatgacagat
    36361 aactacgaaa tccaaagtcg agcaacttcc tcttgggaac atggcaatcc gattcataag
    36421 gggactcagg gaatttttca agagtatgag attccttatg acaagaacaa gacatcgctt
    36481 cagattagta aggaagattt tgaagccttt gattatatta tcggaatgga cgcttcaaat
    36541 atttctgact tacgtcagat gtgtccagta gactgtcaag ataagattta ctcattttca
    36601 tctgaaagtg ttccagaccc ttggtataca ggagattttg aagaaaccta tcgacgtgtt
    36661 caagagggct gtcaagcttg gttagaacgt ttagaaaagg agagttaagg tggaaaatct
    36721 tacgaatttt tacgaaaagt atcgtgtcta tctgactcgt ccacgtttag agcttttggc
    36781 agtagttacc attgttttct gtgctgtact cgtctttttt ctaaatattc caggaaaagg
    36841 tgtcttaaaa ctcgataatg gaacgattgt ttatgatggc agtcttgtcc gtggtaaaat
    36901 gaatggtcaa ggtaccatta ccttccaaaa tggagaccaa tatacaggtg gcttcaacaa
    36961 tggatccttc aacggaaaag gtacctttca atctaaagaa ggctggacct acgaaggtga
    37021 ttttgtaaat ggtcaggctg aaggaaaagg gaaactaaca acagaacaag aagtcgttta
    37081 tgaaggaact tttaaacaag gcgtttttca acaaaaataa agcctcctta tccaaaggag
    37141 gtattattag aaccacaagg taagcgctta cctgtaaatc cctttctttc caaatccctc
    37201 ttccaagcaa gtttgtgaaa taaaaaatat ttgaaataaa tttcacaaac ttcaaagata
    37261 aaacctgatg agaaaagaaa atgagaaaag tttcacaaga gtttaaaaat tctttgtgaa
    37321 atgtttatga aactgtttac aaagttgaaa taatgcgtta taataaactt gtgaaaaaat
    37381 taacaaagga tatcgttcct tgaaagctat ggaggaaaat atggctgata aaaaaactgt
    37441 gacaccagag gaaaagaaac tcgttgctga aaaacacgta gatgagttgg ttcaaaaagc
    37501 tctagttgcc cttgaagaaa tgcgtaaatt ggatcaagag caagttgact acatcgttgc
    37561 caaagcatca gtagcagctt tggatgccca cggagaattg gctttacatg cctttgaaga
    37621 aacaggacgt ggtgtatttg aagataaagc aactaagaac ttgtttgcct gtgaacacgt
    37681 agtaaacaac atgcgtcaca ctaagacagt tggcgttatc gaagaagacg atgtaacagg
    37741 attgactctt attgctgaac cagttggtgt tgtttgtggt attactccaa caacaaaccc
    37801 aacatcaaca gcaatcttca aatcattgat ttcattgaag acacgtaacc caatcgtctt
    37861 tgccttccat ccatcagcac aagaatcatc tgctcatgca gctcgtatcg tccgcgatgc
    37921 agctatcgca gctggtgctc ctgaaaactg tgtgcaatgg attactcaac catctatgga
    37981 agcaacaagt gcccttatga accacgaagg tgttgcgaca atccttgcaa caggtggtaa
    38041 tgccatggtt aaggcggctt attcatgtgg taaaccagct cttggggtag gtgccggaaa
    38101 cgttccagct tatgttgaaa aatcagcaaa cattcgtcaa gcagcacacg atatcgtcat
    38161 gtctaaatca tttgataacg gtatggtctg tgcatctgaa caagcagtta tcattgataa
    38221 agaaatttac gatgaatttg tagcagagtt caaatcttac cacacttact ttgtaaacaa
    38281 aaaagaaaaa gctcttcttg aagagttctg cttcggcgtc aaagcaaaca gcaaaaactg
    38341 tgctggtgca aaattgaacg ctgacatcgt tggtaaacca gcaacttgga ttgcagaaca
    38401 agcaggattt acagttccag aaggaacaaa cattcttgct gcagaatgta aagaagttgg
    38461 cgaaaatgag ccattgactc gtgaaaaatt gtcaccagtt attgcagttt tgaaatctga
    38521 aagccgtgaa gatggtatta ctaaggctcg tcaaatggtt gaatttaacg gtcttggaca
    38581 ctcagcagct atccacacag ctgacgaaga attgactaaa gaatttggta aagctgttaa
    38641 agctattcgt gttatctgta actcaccttc tacttttggt ggtatcgggg acgtttacaa
    38701 tgccttcttg ccatcattga cacttggatg tggttcttac ggacgcaact cagttgggga
    38761 taacgttagt gccattaacc tcttgaatat caaaaaagtc ggaagacgga gaaataacat
    38821 gcaatggatg aaacttcctt caaaaacata ctttgaacgt gattcaattc aataccttca
    38881 aaaatgtcgt gacgttgaac gtgtcatgat cgttactgac catgccatgg tagagcttgg
    38941 tttccttgat cgtatcatcg aacaactgga ccttcgtcgc aataaggttg tttaccaaat
    39001 ctttgcggat gtagaaccgg atccagatat cacaactgta aaccgtggta ctgagattat
    39061 gcgtgccttc aaaccagata ccatcatcgc actcggtggt gggtctccaa tggatgctgc
    39121 caaagtaatg tggctcttct acgagcaacc agaagtggac ttccgtgacc ttgtccaaaa
    39181 attcatggat atccgtaaac gtgccttcaa gttcccattg cttggtaaga agactaaatt
    39241 catcgcgatt ccaactacat ctggtacagg atctgaagta acaccatttg ccgttatctc
    39301 tgataaagca aacaaccgta aatacccaat cgctgactac tcattgacac caactgtggc
    39361 aatcgtagat cctgctttgg tattgacagt tccaggattt gttgctgctg atactggtat
    39421 ggacgtattg actcacgcga cagaagcata cgtatcacaa atggctagtg actacactga
    39481 tggtttagca cttcaagcca ttaaattggt ctttgaaaat ctcgaaagct cagttaagaa
    39541 tgcagacttc cactcacgtg agaaaatgca taacgcttca acaatcgctg gtatggcctt
    39601 tgccaatgcc ttcctaggta tttctcactc aatggcccat aagattggtg cgcaattcca
    39661 cacaatccac ggtcgtacaa atgctatctt gcttccgtac gttatccgtt acaatggtac
    39721 acgtccagct aagacagcaa catggcctaa gtacaactat taccgtgcag atgaaaaata
    39781 ccaagatatc gcacgcatgc ttggacttcc agcttctact ccagaagaag gggttgaatc
    39841 ttacgcaaaa gctgtctacg aactcggtga acgtattggg atccaaatga attttagaga
    39901 ccaaggaatt gacgaaaaag aatggaaaga acattctcgt gaattagcct tcctggctta
    39961 tgaagaccaa tgttcaccag ctaacccacg tcttccaatg gtagaccata tgcaagaaat
    40021 catcgaagat gcatactatg gctacaaaga aagaccagga cgccgtaaat aattgtttat
    40081 cagtctagaa gcaagacaaa aactcaattt gagggaaaga tccagtaatt tttctatgat
    40141 aaaaggcatc ctatcaaggt ttttgaatac ctgataggat gcctttttat gatgttgggg
    40201 cctttttgcc ctttttgaaa aactagaata gaaacaaaat atatagcaga ttgaaactag
    40261 aatagtacac atctgcttct aaaacattgt tagaattcga tttgattttc ctgatcgatt
    40321 tgtcctattc ctatttcatt ttactatact atataaaaaa tata
//
LOCUS       DAVLZS010000017        38611 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLZS010000017 DAVLZS010000000
VERSION     DAVLZS010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.017"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            371..598
                     /locus_tag="VYO88_000932"
     CDS             371..598
                     /locus_tag="VYO88_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719052.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="VYO88_000933"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="VYO88_000933"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV1719053.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4798..5250
                     /locus_tag="VYO88_000934"
     CDS             4798..5250
                     /locus_tag="VYO88_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1719054.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5269..6606
                     /locus_tag="VYO88_000935"
     CDS             5269..6606
                     /locus_tag="VYO88_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1719055.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6685..7569
                     /locus_tag="VYO88_000936"
     CDS             6685..7569
                     /locus_tag="VYO88_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1719056.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7569..8402
                     /locus_tag="VYO88_000937"
     CDS             7569..8402
                     /locus_tag="VYO88_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1719057.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8420..10513
                     /gene="nanB"
                     /locus_tag="VYO88_000938"
     CDS             8420..10513
                     /gene="nanB"
                     /locus_tag="VYO88_000938"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1719058.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKADFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10525..11628
                     /locus_tag="VYO88_000939"
     CDS             10525..11628
                     /locus_tag="VYO88_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1719059.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDVCKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11802..12500
                     /locus_tag="VYO88_000940"
     CDS             11802..12500
                     /locus_tag="VYO88_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1719060.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12519..14036
                     /locus_tag="VYO88_000941"
     CDS             12519..14036
                     /locus_tag="VYO88_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1719061.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPML
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            14161..15489
                     /locus_tag="VYO88_000942"
     CDS             14161..15489
                     /locus_tag="VYO88_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1719062.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15741..16607
                     /locus_tag="VYO88_000943"
     CDS             15741..16607
                     /locus_tag="VYO88_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1719063.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16623..17462
                     /locus_tag="VYO88_000944"
     CDS             16623..17462
                     /locus_tag="VYO88_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1719064.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17735..18187
                     /locus_tag="VYO88_000945"
     CDS             17735..18187
                     /locus_tag="VYO88_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1719065.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEALAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            18284..18628
                     /locus_tag="VYO88_000946"
     CDS             18284..18628
                     /locus_tag="VYO88_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719066.1"
                     /translation="MVSSKHAARASFLDGQEITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGIGIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            18912..19556
                     /locus_tag="VYO88_000947"
     CDS             18912..19556
                     /locus_tag="VYO88_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1719067.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19725..20642
                     /locus_tag="VYO88_000948"
     CDS             19725..20642
                     /locus_tag="VYO88_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1719068.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20660..21544
                     /locus_tag="VYO88_000949"
     CDS             20660..21544
                     /locus_tag="VYO88_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1719069.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21560..22411)
                     /locus_tag="VYO88_000950"
     CDS             complement(21560..22411)
                     /locus_tag="VYO88_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1719070.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLEQIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22611..24668
                     /gene="pbp2b"
                     /locus_tag="VYO88_000951"
     CDS             22611..24668
                     /gene="pbp2b"
                     /locus_tag="VYO88_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1719071.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24679..25275
                     /gene="recR"
                     /locus_tag="VYO88_000952"
     CDS             24679..25275
                     /gene="recR"
                     /locus_tag="VYO88_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1719072.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25451..26494
                     /locus_tag="VYO88_000953"
     CDS             25451..26494
                     /locus_tag="VYO88_000953"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1719073.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            26578..27951
                     /locus_tag="VYO88_000954"
     CDS             26578..27951
                     /locus_tag="VYO88_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1719074.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGENIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGVHDQILLKGSNSMNLAKLVE
                     SLENEAK"
     gene            27938..28549
                     /locus_tag="VYO88_000955"
     CDS             27938..28549
                     /locus_tag="VYO88_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1719075.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDVEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28640..29344
                     /locus_tag="VYO88_000956"
     CDS             28640..29344
                     /locus_tag="VYO88_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1719076.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29563..30936
                     /gene="ftsA"
                     /locus_tag="VYO88_000957"
     CDS             29563..30936
                     /gene="ftsA"
                     /locus_tag="VYO88_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1719077.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYATKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            30953..32212
                     /gene="ftsZ"
                     /locus_tag="VYO88_000958"
     CDS             30953..32212
                     /gene="ftsZ"
                     /locus_tag="VYO88_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1719078.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32217..32888
                     /locus_tag="VYO88_000959"
     CDS             32217..32888
                     /locus_tag="VYO88_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1719079.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32898..33437
                     /locus_tag="VYO88_000960"
     CDS             32898..33437
                     /locus_tag="VYO88_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1719080.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33437..33700
                     /locus_tag="VYO88_000961"
     CDS             33437..33700
                     /locus_tag="VYO88_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1719081.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33697..34482
                     /locus_tag="VYO88_000962"
     CDS             33697..34482
                     /locus_tag="VYO88_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1719082.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQKIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLNK"
     gene            34491..35279
                     /gene="divIVA"
                     /locus_tag="VYO88_000963"
     CDS             34491..35279
                     /gene="divIVA"
                     /locus_tag="VYO88_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1719083.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35627..38419
                     /locus_tag="VYO88_000964"
     CDS             35627..38419
                     /locus_tag="VYO88_000964"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1719084.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLFAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPDLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIVEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        12046 a         6770 c         8370 g        11425 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtgtaaatag cataagctga tgtccatcat ttgcttataa agagatagtt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaatttggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aaattaataa aagacaaact aagtgcattt tctggaataa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattag gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aagaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga gggagaaaag gaagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagtg acaagggtga tctatacaag ggtgaccaat tactaggaaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 gaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcaag ctgatacgaa atcataagag gtctgaaact
     3901 actttcaggg tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 accaggaaag tcaaattaat ttatagaatt attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatgtgacta ttaaccttgt cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atactaaaaa aaaaaagtat actctaattg aaaacggtaa caaaactaat ttagagaatg
     4261 aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt
     4321 agccaaagag tctattagtg ctagaataat agattagaat tattttagaa aaacgaagtg
     4381 agcagcttat aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa
     4441 agggcgactt ccttcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa
     4501 cttatttatt ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt gaggagatac
     4561 tgaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcttt
     4621 gaggttgtag ataagactga cgtatataat ccaaggtgaa gcgactgtgc tttgaagaga
     4681 ttttcaaaga gtataggcta gagagtagtg tttttatgtt cttctagtag aaaatgctag
     4741 acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg
     4801 attattacaa aaattagccg tttaggaact tatgtgggag tcaatccaca ttttgcaaca
     4861 ttaatagatt ttctagaaaa aacaggacta gaaaatttaa cagaaggttc gattgctatc
     4921 gatggtaatc gattgtttgg gaattgcttt acttatctag cagatggtca agcaggggct
     4981 ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc
     5041 atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat
     5101 attgaattat acacagggaa agtggaacag ttggttcatt tgagagctgg tgaatgcctc
     5161 atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa
     5221 aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg
     5281 agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca
     5341 ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca
     5401 atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct
     5461 ttcatgcaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc
     5521 tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt
     5581 cctaaccaag taatggaaat ggtcaactca gacgctttgg ttccgctaaa tgattctatc
     5641 aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat
     5701 gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg
     5761 ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa
     5821 aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg
     5881 gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat
     5941 cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg
     6001 tataaagaaa tctcacctca agattctttg aactttaatg tccttcaaca agctaccttg
     6061 ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat
     6121 gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag
     6181 tctgataaag accaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca
     6241 aaacatccag aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt
     6301 aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct
     6361 gcagcctata aagaaaatga aactcgtaag aaatttaaac atgctgaaga agtaattact
     6421 gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt
     6481 atgttaacta accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca
     6541 gatcctatga aagcagcaaa agaagcagaa aaacaattaa acgatttatt tgaggctgtt
     6601 cagtagatgt aaaagactag aaaataggtg ggctagtgag ctgaaaagct ctagcccaat
     6661 cttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt
     6721 gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt
     6781 ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct
     6841 aactataaag ctgtgctatc agatcccaac ttctttaatg cgttctttaa ttcaattaag
     6901 tggaccgttt tctcattagt tggtcaagtt ttagtagggt ttgtattggc tttagctctt
     6961 cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt
     7021 cctaccatcg ttattgcctt ctcttggcag tggattctaa acggggttta tggctactta
     7081 cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt
     7141 acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg
     7201 gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata
     7261 gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt
     7321 gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga cattatctac
     7381 ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttacaac
     7441 ctgggctggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc
     7501 ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt
     7561 agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag
     7621 ttggtgcgac catcgttgca gttttcccat tggtatggat tatcatatct tctgtcaaag
     7681 ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt acattagatt
     7741 atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca
     7801 ttgccttggc tacaaccctc attgcgatta ttatttctgc tatggcagcc tatggtattg
     7861 ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctatattt
     7921 tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa
     7981 atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc
     8041 tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg
     8101 gtgcaaataa atttgttacg ttttataaag ttgtgctacc gattgtagca ccaggtattg
     8161 tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt
     8221 tgattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag
     8281 aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta
     8341 ttttcttctc tatcatccaa aataagattg caagtggatt atcagaagga tctgtgaagt
     8401 agacgaaaga aggaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttctgt
     8461 tgtaggcatt agtcttttaa tgggagttcc cactttgatt catgcgaatg aattaaacta
     8521 tggtcaactg tccatatctc ctatttttca aggaggttca tatcaactga acaataagag
     8581 tatagatatc agctctttgt tattagataa attgtctgga gagagtcaga cagtagtaat
     8641 gaaatttaaa gcagatgaac caaactctct tcaagctttg tttggcctat ctaatagtaa
     8701 agcagacttt aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt
     8761 agaaataaga gacgcccaaa agggaataaa ttatttattt tccagaccag cttcattatg
     8821 gggaaaacat aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga
     8881 taaaacatac acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt
     8941 tttgccaatt tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga
     9001 aggtaaggaa cattacctcg caaaaggaag tattgatgaa atcagtctat ttaacaaagc
     9061 aattagtgat caggaagttt caaatattcc cttgtcaaat ccatttcagt taattttcca
     9121 atcaggagat tctactcaag ctaactattt tagaataccg acactatata cattaagtag
     9181 tggaagagtt ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa
     9241 gattaatatt gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt
     9301 tgctatgaag tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt
     9361 aaagaatagt caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa
     9421 aaaatctggg aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa
     9481 tgcaaataaa gccgactcag gttttaaaga aataaatggt cattattatt taaaactaaa
     9541 gaagaatgga gataacgatt tccgttatac agttagagaa aatggtgtcg tttatgatga
     9601 aacaactaat aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg
     9661 aaagtcttta acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaaa
     9721 acataatgga aaacaggttc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac
     9781 tcctactaat tatatagcaa tgacaactag tcagaataga ggagagagtt gggaacaatt
     9841 taagttgttg cctccgttct taggagaaaa acataatgga acttacttgt gtcctggaca
     9901 aggtttagca ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact
     9961 aacctatctc atttctgatg atagtggtca aacatggaag aaatcctcag cttcaattcc
    10021 gtttaaaaat gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac
    10081 attctttaga accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac
    10141 atggtcggaa gtttcgtata ttgatggaat ccaacaaact tcatatggca cacaagtatc
    10201 tgcaattaaa tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa
    10261 ttctagaagt ggccgtaagg gaggtcaatt agttgtcggt ttagtcaata aagaagatga
    10321 tagtattgat tggaaatacc actatgatat tgatttgcct tcgtatggtt atgcctattc
    10381 tgcgattaca gaattgccaa atcatcacat aggtgtactg tttgaaaaat atgattcgtg
    10441 gtcgagaaat gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga
    10501 tttaacaaaa taaaggagaa aaacatggtt aaatacggtg ttgttggagc agggtatttt
    10561 ggagctgaat tggctcgcta catgcaaaaa aatgatggag cagagattac tcttctctat
    10621 gatccagata atgcagaggc gattgcagaa gaattgggag caaaagtagc aagttcctta
    10681 gatgagttgg tttctagcga tgaagtagac tgtgttatcg tcgcaactcc aaataatctt
    10741 cataaggaac cggttattaa ggctgcacag catggtaaaa atgttttctg tgaaaaacca
    10801 attgcgcttt cttatcaaga ttgtcgcgag atggtagatg tgtgtaaaga aaacaatgta
    10861 acctttatgg caggacatat tatgaatttc tttaatggtg ttcatcatgc aaaagaactc
    10921 attaatcaag gagttatcgg agacgttcta tattgtcata cagctcgtaa tggttgggaa
    10981 gaacaacaac cgtcagtatc atggaaaaaa attcgtgaaa aatcaggtgg tcacttgtat
    11041 caccacatcc atgaattgga ttgcgttcaa ttccttatgg ggggcatgcc tgaaactgta
    11101 accatgacag gtggaaatgt ggcccatgaa ggtgaacatt tcggtgatga agatgatatg
    11161 atttttgtca atatggaatt ttctaataag cgttttgctt tgttagaatg gggttcagct
    11221 tatcgttggg gtgaacatta tgtcttaatc caaggaagca aaggtgccat ccgcttagac
    11281 ttattcaact gtaaaggaac tcttaagcta gatgggcaag aaagctattt cttgattcac
    11341 gaatcgcaag aagaagatga tgatcggact cgtatctatc atagtacaga gatggatgga
    11401 gcaattgctt atggtaaacc aggtaaacgt actccattat ggctatcatc tgtcattgat
    11461 aaagaaatgc gctatctgca tgagattatg gaaggagctc cagtatcaga agaatttgca
    11521 aaacttttga caggtgaagc tgccctagaa gcaattgcta ctgcagatgc ttgtacccag
    11581 tctatgtttg aagatcgcaa agtaaaattg tcagaaattg taaaataaat tttggtattc
    11641 tcctatttat aggtcgactt gctcctctga aagtactttt agaggagctg tttgactttg
    11701 ctagtttttg aaactgaaat ctattatact acaaactatt gaaagcgttt taattttaag
    11761 gtataataat ctcatagaaa taaagaaaag gaggaaagag gatgccacag attagcaaag
    11821 aagccttgat tgagcaaatc aaagatggaa tcatcgtttc ttgtcaggct cttcctcatg
    11881 aaccgcttta tacagaagcg ggaggggtga ttcccttgct ggtcaaagcg gctgagcaag
    11941 gtggagcagt cggtatccga gcaaacagtg ttcgcgatat caaggaaatt aaggaggtca
    12001 ctaaacttcc aatcattggg attatcaaac gtgattatcc acctcaggaa cccttcatca
    12061 cggctactat gaaagaagtt gatgaattgg cagaactgga catcgaggtg attgctctgg
    12121 attgtaccaa gcgtgaacgc tacgatggtt tggaaattca agagttcatt cgtcaggtta
    12181 aggagaaata tcctaatcag cttttgatgg ctgatactag tatcttcgaa gaagggctag
    12241 cagctgtaga agcaggaatt gactttgtcg gaacaacctt atcaggctac acatcctaca
    12301 gtccaaaagt agacggtcca gattttgaat tgattaagaa actctgtgat gccggtgtag
    12361 atgtcattgc agaaggaaaa attcatacac cagaacaagc caaacaaatc cttgaatatg
    12421 gagtgcgagg catcgttgtt ggtggcgcca ttactagacc aaaagagatt acagaacgct
    12481 tcgttgctag tcttaaataa gatgtgaggg ggagttttat gtttaaagtt ttacaaaaag
    12541 ttggaaaagc ttttatgtta cctatagcta tacttcctgc agcaggtcta cttttgggga
    12601 ttggtggtgc actttcaaac ccaaccacga tagcaactta tccaatgcta gacaatagta
    12661 tttttcaatc aatattccaa gtaatgagct ctgcaggaga ggttgtattc agtaatttgt
    12721 cactacttct ctgtgtggga ttatgtattg gcttagcgaa acgagataaa ggaaccgctg
    12781 cgttagcagg agtaactggt tacttagtta tgactgcaac gatcaaagct ttagtaaaac
    12841 tttttatggc agaaggatct gcaattgata ctggagttat tggagcatta gttgtcggaa
    12901 tagttgccgt atatttgcac aaccgatata acaatattca attaccttcc gctttaggat
    12961 tctttggagg ttcacgcttc gttcctattg ttacatcgtt ctcttctatc ttgattggct
    13021 ttgtcttctt tgttatttgg ccacctttcc aacaacttct tgtttctaca ggtggatata
    13081 tttctcaggc gggtccaatt ggaacttttc tatatggatt tttaatgaga ctttctggag
    13141 cagtaggctt acatcatata atttacccta tgttttggta tactgaactt ggtggtgttg
    13201 aaactgttgc aggacaaaca gtggttggag ctcaaaaaat attttttgct caattagccg
    13261 atctggccca ttctggatta tttacagaag gaacaaggtt ttttgcaggt cgtttctcaa
    13321 caatgatgtt cggtttaccg gctgcctgtt tagcgatgta ccatagtgtt cctaaaaatc
    13381 gtcgtaaaaa atacgcgggt ttgttttttg gagttgcttt aacatctttt attaccggta
    13441 ttacagaacc aattgaattt atgtttctat tcgtcagtcc ggttctatat gttgttcacg
    13501 cattccttga tggtgttagc ttctttattg cagacgtctt aaatatttca ataggaaaca
    13561 cattttcagg aggtgtaatc gatttcactt tatttggaat tttgcagggg aacgctaaga
    13621 cgaattgggt tcttcagatt ccatttggac ttatttggag tgttttgtat tatattattt
    13681 ttagatggtt cattactcaa ttcaacgttc taacgccagg gcgaggagaa gaagtagatt
    13741 ctaaagaaat ttctgaatcc gcagattcaa cttcaaatac tgcagattat ttaaaacagg
    13801 atagcctaca aattatcaga gccttgggtg gatcaaataa tatagaagat gtagatgctt
    13861 gtgtgacacg tttacgtgta gctgtaaaag aagttaatca agttgataaa gcacttttaa
    13921 aacaaattgg tgcagttgat gtcttagaag tgaagggtgg cattcaagca atctatggag
    13981 caaaagcaat cttatataaa aatagtatta atgaaatttt aggtgtagat gattaagtac
    14041 ttactgactt aataaaaaac agaggagagt gatggatgag taggatgaaa tgaaatcgca
    14101 tacaagaaat aaagaactca ttatccaagt tggatacgct tattacatag gagaatacaa
    14161 atgaaattta gaaaattagc ttgtacagta cttgcgggtg ctgcggttct tggtcttgct
    14221 gcttgtggca attctggcgg aagtaaagat gctgccaaat caggtggtga cggtgccaaa
    14281 acagaaatca cttggtgggc attcccagta tttacccaag aaaaaactgg tgacggtgtt
    14341 ggaacttatg aaaaatcaat catcgaagcg tttgaaaaag caaacccaga tataaaagtg
    14401 aaattggaaa ccatcgactt caagtcaggt cctgaaaaaa tcacaacagc catcgaagca
    14461 ggaacagctc cagacgtact ctttgatgca ccaggacgta tcatccaata cggtaaaaac
    14521 ggtaaattgg ctgagttgaa cgacctcttc acagatgaat ttgttaaaga tgtcaacaat
    14581 gaaaacatcg tacaagcaag taaagctgga gacaaggctt atatgtatcc gattagttct
    14641 gccccattct acatggcaat gaacaagaaa atgttagaag atgctggagt agcaaacctt
    14701 gtaaaagaag gttggacaac tgatgatttt gaaaaagtat tgaaagcact taaagacaag
    14761 ggttacacac caggttcatt gttcagttct ggtcaagggg gagaccaagg aacacgtgcc
    14821 tttatctcta acctttatag cggttctgta acagatgaaa aagttagcaa atatacaact
    14881 gatgatccta aattcgtcaa aggccttgaa aaagcaacta gctggattaa agacaatttg
    14941 atcaataatg gttcacaatt tgacggtggg gcagatatcc aaaactttgc caacggtcaa
    15001 acatcttaca caatcctttg ggcaccagct caaaatggta tccaagctaa acttttagaa
    15061 gcaagtaagg tagaagtggt agaagtacca ttcccatcag acgaaggtaa gccagctctt
    15121 gaataccttg taaacggatt tgcagtattc aacaataaag acgacaagaa agtcgctgca
    15181 tctaagaaat tcatccagtt tatcgcagat gacaaagagt ggggacctaa agacgtagtt
    15241 cgtacaggtg ctttcccagt ccgtacttca tttggaaaac tttatgaaga caaacgcatg
    15301 gaaacaatca gcggctggac tcaatactac tcaccatact acaacactat tgatggtttt
    15361 gctgaaatga gaacactttg gttcccaatg ttgcaatctg tatcaaatgg tgacgaaaaa
    15421 ccagcggatg ctttgaaagc cttcactgaa aaagcaaacg aaacaatcaa aaaagctatg
    15481 aaacaatagt ccttagttat tctataaaaa gtagtttttt aaagaaccta agagtgtata
    15541 cccccttttc cctctacaca gatagtgtaa gaaaaggggg cttttgttta aaatgtaaga
    15601 aactgtcacg aaattaaaat gaagttctta cataagcgaa tcataaaaaa tttcattttg
    15661 attttaaaac agttcaagaa agtcaaaaaa ttattctatt tgaaagagag gtgccgactg
    15721 tgaaagtcaa taaaatccgt atgcgggaaa cagtgatttc ctacgctttc ctagcaccag
    15781 tattattctt ctttgtcatc tttgtgttgg ctccgatggt gatgggcttc attacaagtt
    15841 tctttaacta ctcaatgact aaatttgagt ttgtaggctt ggataactat atccgtatgt
    15901 ttaaagatcc tgtctttaca aaatctctga ttaacacagt tattttggtt attggatctg
    15961 taccagttgt tgttctattc tcactctttg tagcatctca gacctatcat caaaatgtca
    16021 ttgccagatc cttctaccgt ttcgtcttct tccttcctgt tgtaacgggt agtgttgccg
    16081 tgacagttgt ttggaaatgg atttatgacc cactatcagg gattctaaac tttgtcctta
    16141 agtcaagcca catcatcagc caaaacattt cttggttggg agataaaaac tgggcattga
    16201 tggcgattat gattattctc ttgaccactt cagttggtca gcccatcatc ctttatatcg
    16261 ctgccatggg gaatattgac aattcactgg ttgaagcggc gcgtgttgat ggtgcaactg
    16321 agtttcaagt tttttggaag attaaatggc caagccttct tccaacaact ctttatattg
    16381 caatcatcac aacaattaac tcattccagt gtttcgcctt gattcagctt ttgacatctg
    16441 gtggtccaaa ctactcaaca agtaccttga tgtactacct ttacgaaaaa gccttccaat
    16501 tgacagaata cggctatgcc aacacaattg gtgtcttctt ggcagtcatg attgctatcg
    16561 taagctttgt tcaatttaaa gtacttggaa acgacgtaga atactaaaga aaggagacag
    16621 ctatgcaatc tacagaaaaa aaaccattaa cagcctttac tgttatttca acaatcattt
    16681 tgctcttgtt gactgtgctg ttcatctttc cattctactg gattttgaca ggggcattca
    16741 aatcacaacc tgatacaatt gttattcctc ctcagtggtt ccctaaaatg ccaaccatgg
    16801 aaaacttcca acaactcatg gtgcagaacc ctgccttgca atggatgtgg aactcagtat
    16861 ttatctcatt ggtaaccatg ttcttagtct gtgcaacctc atctctagca ggttatgtat
    16921 tggctaaaaa acgtttctat ggtcaacgca ttctatttgc tatctttatc gctgctatgg
    16981 cgcttccaaa acaagttgtc cttgtaccat tggtacgtat tgtcaacttc atgggaatcc
    17041 acgatactct ctgggcagtt atcttgcctt tgattggatg gccattcggt gtcttcctca
    17101 tgaaacaatt tagtgaaaat attcctacag agttgcttga atcagctaaa atcgacggtt
    17161 gtggtgagat tcgtaccttc tggagtgtag ccttcccgat tgtgaaacca gggtttgcag
    17221 cccttgcaat ctttaccttc atcaatactt ggaatgacta cttcatgcaa ttggtaatgt
    17281 tgacttcacg taacaatttg accatctcac ttggggttgc gaccatgcag gctgaaatgg
    17341 caaccaacta tggtttgatt atggcaggag ctgcccttgc tgctgttcca atcgtcacag
    17401 tcttccttgt cttccaaaaa tccttcacac agggtattac tatgggagcg gtcaaaggat
    17461 aatactctgc gaaaatcgaa tgcaaactac gtcagcttca ccttgccata cttaagtatt
    17521 gcctgcggtt agcttcctag tttgttcttc aattttcatt gagtatagga aaatcaatct
    17581 atcaagatac agaagtatat tttatagatt tagagaatat agaagttata agtgtctaca
    17641 aaatggaggg tatgcagtta ctttatgaag ttttgtcaga cacttatcaa cttaagaatg
    17701 attttagtta attatcagaa acgaaggaaa gagtatgatt tttgacgatt tgaaaaacat
    17761 caccttttac aaagggattc atcccaattt agacaaagct atcgactacc tctaccaaca
    17821 tcgtaaagat tcattcgaat taggaaagta tgagattgat ggagataagg tctttctagt
    17881 tgttcaggaa aatgtcctca atcaagttga gaataatcaa tttgaacacc ataagaacta
    17941 tgcagatttg catttgctga tagaagggca tgaatattcg agctacggtt cacgtatcaa
    18001 agacgaggca ttagcattcg acgaagcgac tgacattggc tttgttcatt gtcatgaaca
    18061 ctacccactc ttgttgggtt atcataattt tgcgattttc ttcccaggtg agccacatca
    18121 gccaactggc tatgcaggta tggaagaaaa ggttcgaaaa tatctcttta aaattttgat
    18181 tgattaaaaa taggatgaat tgtttttttg taaagctttg acaatactct accatgaaat
    18241 tgatctttat gaggtagaga aatgagaata aaatatttaa aaattggtat cttctaagca
    18301 tgctgcaaga gctagtttct tagatggaca ggaaattaca gttgatgaga tgtcctggat
    18361 aattaatggc attgtgaatg cattgattgg tagatacata aaattaggta cttatgcagc
    18421 taagtatggt attggtatag cacgctcgat cttaagtagg gcagctgcaa ctgcagcagc
    18481 aagagtagga ttactgacca agatttctgg atggatttta cgagtagctg tgaatgtagc
    18541 tgatgtatat ggtaatttcg ccaacaatat tgctgcagct tgggatgcat atgataaaat
    18601 tcctaacaat ggtcgtataa acttttaaaa tacgagaatg aaagcacttt gtattttttt
    18661 attgaatatg ttagcttgga cagtgcttgc aatgataatt cgtggagggc tagatggatt
    18721 tgataggcat acttggagta ctattttaat tgcttcgctg ttcggggtat atgattataa
    18781 gcccatagat aaaaatagaa aaaagtccaa aagaaaaaag aaaaaataga tttgttcatg
    18841 gtagggactt atgaaagctt tactgacaaa aaagaaaaca gtttacaaag aaaaatgatg
    18901 gaggagcaaa catggcacaa aaaggagtaa gccttatcaa ggcagcattt gatacagata
    18961 actttctcat gcgttttagt gagaaggtct tggacatcgt gacagccaat cttctttttg
    19021 tcgtctcttg tttacccatc gtgacgattg gagtggctaa aatcagcctc tacgagacca
    19081 tgttcgaagt taagaagagc agacgggtgc ctgtttttaa aatctatcta agatctttca
    19141 agcaaaatct gaaactaggt cttcagctgg gtttaatgga gttaggaatt gtgtttctta
    19201 ccctttcaga tctctatctt ttctggggtc aaacagctct gcccttccaa ttgctgaaag
    19261 ccatttgttt aggtattctg atttttctta ctatcgtgat gctggctagt taccctatcg
    19321 cggcacgtta tgacctatct tggaaagaaa ttcttcaaaa aggattgatg ttggctagtt
    19381 ttaactttcc ttggttcttc ctcatgttag ccattcttgt cctcattgtg atggttcttt
    19441 atctgtccgc cttcagtcta ctcttaggtg gctcagtctt cctacttttt gggtttggac
    19501 tattggtctt tatccagact ggattgatgg agaaaatttt cgcaaaatac caataggagc
    19561 tttatttctg aaactacttt caaaggctcc aaacgctatt ctataagcga gaaactaaaa
    19621 tctaagtgtc tataagatat tgaaagcctt ttcggtaaag tgtatactaa agaagtaaag
    19681 aaaaatctgc tttagcagaa aataaaaata ataggagaaa atctatgtca gatttgaaaa
    19741 aatacgaagg tgtcattcca gccttctacg catgttatga tgagcaagga gaagtaagtc
    19801 cagagcgtac gcgtgccttg gttcaatact tcattgataa aggtgttcaa ggtctttatg
    19861 tcaatggttc ttctggtgaa tgtatctacc aaagcgttga agatcgcaag ttgattttgg
    19921 aagaagtcat ggcggtagct aaaggtaaat tgaccattat tgcccatgtt gcctgcaaca
    19981 atactaaaga cagtatggaa cttgctcgcc atgctgaaag cttgggagta gatgctattg
    20041 caacgattcc accaatttac ttccgcttgc cagaatactc agttgccaaa tactggaacg
    20101 atattagttc tgcagctcca aacacagact acgtgattta caacattcct caattggcag
    20161 gggttgcttt gactccaagc ctttacacag aaatgttgaa aaatcctcgt gttatcggtg
    20221 ttaagaactc ttctatgcca gttcaagata tccaaacctt tgtcagcctt ggcggggaag
    20281 accatattgt ctttaacggt ccagatgaac agttcctagg tggccgcctc atgggtgcta
    20341 gggctggtat cggtggtact tatggtgcta tgccagaact cttcttgaaa ctcaatcagt
    20401 tgattgcgga taaggaccta gaaacagcgc gtgaattgca gtatgctatc aacgcaatca
    20461 ttggtaaact cacttctgct catggaaata tgtacggtgt catcaaagaa gttttgaaaa
    20521 tcaatgaagg cttgaatatt ggatctgttc gttcaccatt gacaccagtg actgaagaag
    20581 atcgtccagt tgtagaagcg gctgcagcct tgattcgtga aaccaaggag cgcttcctct
    20641 aatctaaaag gaggtattta tgacatacta cgttgcaatt gatatcggtg gaactaacat
    20701 caagtatggt ttggttgatc aagaggggca acttcttgaa tcgcatgaaa tgccaactga
    20761 ggcgcataag ggtggacctc atatcttaca aaagaccaaa gatatcgtag ctagttattt
    20821 agaaaaaggc ccagtagcag gtgttgccat atcttctgct gggatggtgg atccggataa
    20881 gggtgagatt ttctatgctg ggccgcaaat ccctaactac gcaggcaccc agttcaaaaa
    20941 ggaaatcgaa gaaagcttta ctattccttg tgagattgaa aatgatgtca actgtgcagg
    21001 tcttgctgag gcagtatctg gttcaggcaa gggagcaagt gtgacacttt gcttgaccat
    21061 tggaacaggt atcggtggtt gcttgattat ggataggaaa gtcttccatg gttttagtaa
    21121 ttcagcctgt gaagtcgggt atatgcatat gcaggatgga gcttttcaag acttggcttc
    21181 tacaacagct ttagtgaaat atgtagctga agcccatgga gaagatgttg atcagtggaa
    21241 tggccgacgt atctttaagg aagctactga aggaaacaaa atctgcatgg aaggtattga
    21301 ccgtatggtt gactatctag gaaaaggtct ggcaaatatt tgctacgttg ccaatccaga
    21361 agtggttatt cttggtggtg gtatcatggg gcaagaggct atcctcaaac ctaagatccg
    21421 cacagccttg aaagaggctt tggtaccaag tttagcagaa aaaacacgat tagaatttgc
    21481 ccatcaccaa aatacagcag ggatgttggg tgcatattat cattttaaga caaaacaatc
    21541 ctagtttggc tcagccaaac taggattttc ttacacgttt ttgtctacga tagccgttga
    21601 gttttttatt ttcccagtag ctattaaaga ttttttcctt gctttcgcga ttgatttcca
    21661 aaaagtaggc ataaatcaaa tcgataaaga agagcatagg aagttgagcg gatattcgtt
    21721 ggatatagga gggttggctg tgggtggcta caagaacagt ctctgtatag gtctggctat
    21781 ctttattggg aacacttgta aagagtacag tctttgcccc catctccttg gcatctaata
    21841 gactatctaa aatagaagga gttgagcctg aaagtgagaa gcccagtact agacaatttt
    21901 catccatgat gctggttgtc caggcaaagc cgtcttggtc tgtcaaagct tcgcagacca
    21961 cacctagtcg cataaaacgt aatttcattt cacgggcgac gaggccagaa ctccctgttc
    22021 caaagaagta gatacgctca gcatcttcga ttagctgggc aatttgctct agttggattt
    22081 cgtcaatcaa gtcttgtgtt tgttccctca tattgctata acttctgagg actcgtttgg
    22141 tcagtggact atgcttggag acttggttgg cttgattttc tgcctgatgt tggtattgga
    22201 aaataaattc tcggtagcca gtaaagccac actttttagc aaagcgggtc aaagcagctt
    22261 gagaaatatg taatttttgg gtgacttgtt gagaagataa atcatctgta atcgtttcag
    22321 cttgcaaaaa atagcgagcg atttcttgct ctaggtctgt catttcttca aaatgtgaat
    22381 caatgatagt tgcgatatct ggtttgtcca tagggaaagc tcctttacat gagtcatact
    22441 ggaagactag atcagggaat agtcacactt cattataaca cataatataa ggatagataa
    22501 ataaaaacgc atctctgttt taaaaacgaa aaaatcgaaa aagcttctct cttttccata
    22561 attttctact caaattgtgg tacaattaag agtaagattt taagttagaa atgagactga
    22621 tttgtatgag aaaatttaac agccattcga ttccgattcg gcttaattta ttgttttcaa
    22681 tcgtcatttt actctttatg accattattg gtcgtttgtt gtatatgcag gttttgaaca
    22741 aggattttta cgaaaaaaag ctagcctcag ctagtcagac caagattaca agcagttcag
    22801 cccgtgggga aatttatgat gctagtggaa aacctttggt agaaaatacg ttaaagcagg
    22861 ttgtttcctt tacgcgtagc aataaaatga cggctacaga cttaaaagaa acagctaaaa
    22921 agttactgac ttatgtgagc atcagttctc caaatttgac agaacgccag ctggcggatt
    22981 actatttggc tgatcctgaa atctataaaa aaatagtgga agctctccca agcgagaaac
    23041 gcttggattc agatggcaat cgtctatccg aatcagaact gtataacaat gcggtcgata
    23101 gtgtacaaac gagtcaacta aactatacag aggatgaaaa gaaagaaatc tatcttttta
    23161 gtcagttaaa tgctgttgga aactttgcga caggaaccat tgcgacagat cctctaaatg
    23221 attctcaggt ggctgttatt gcctctattt caaaggagat gcctggcatt agtatttcta
    23281 cttcttggga tagaaaggtt ttggaaactt ccctttcttc tatagttggg agtgtatcca
    23341 gtgaaaaagc tggtctccca gcggaagaag cagaagccta tcttaaaaaa ggctattctc
    23401 taaatgatcg tgtaggaacc tcctatttgg aaaagcaata tgaagagacc ttacaaggaa
    23461 aacgctcggt aaaagaaatc catctggata aatatggcaa tatggaaagc gtggatacaa
    23521 ttgaggaagg tagtaaggga aacaatatca aactgaccat tgatttggcc ttccaagata
    23581 gcgtggatgc tttactgaaa agttatttca attccgagct agaaaatggt ggagccaagt
    23641 attctgaagg tgtctatgca gtcgccctta acccaaaaac aggtgcggtt ttgtctatgt
    23701 cagggattaa acatgacttg aaaacgggag agttgacgcc tgattccttg ggaacggtaa
    23761 ccaatgtctt tgttccaggt tcggttgtca aggcggcgac catcagctca ggttgggaaa
    23821 atggagtctt gtcaggaaac cagaccttga cagaccagtc cattgtcttc caaggttcag
    23881 ctcccatcaa ttcttggtat actcaggctt acggttcatt ccctatcaca gcggtccaag
    23941 ctctggagta ttcatctaat acctatatgg tccaaacagc cttaggtctt atggggcaaa
    24001 cctatcaacc caatatgttt gtcggcacca gcaatctaga gtctgctatg gagaaactgc
    24061 gttcaacctt tggcgaatat ggcttgggta ctgcgacagg aattgaccta ccagatgaat
    24121 ctactggatt tgttcccaaa gagtatagct ttgctaatta cattactaat gcctttgggc
    24181 agtttgataa ctatacgccg atgcagttgg ctcagtatgt agcaactatt gcaaataatg
    24241 gtgttcgtgt ggctcctcgt attgttgaag gcatttatgg taataatgat aagggaggac
    24301 tgggtgactt gattcagcaa ctgcaaccga cagagataaa taaggtcaat atatccgact
    24361 ccgatatgag catcttgcac caaggttttt atcaggttgc ccatggtact agtggattga
    24421 caactggacg tgccttttca aatggtgcct tggtatccat tagcggaaaa acaggtacag
    24481 ccgaaagcta tgtggcagat ggtcagcaag caaccaatac caatgcggtg gcctatgccc
    24541 catctgataa tccccaaatc gctgtcgcag tggtctttcc tcataatacc aatctaacaa
    24601 atggtgtagg accttccatt gcgcgtgaca ttatcaatct gtatcaaaaa taccatccaa
    24661 tgaactagaa aggaaattat gctttatcca acacctattg ccaagttgat tgacagttat
    24721 tctaagttac caggtatcgg gattaagacg gctacgcgtc tggcctttta tacgattggg
    24781 atgtctgctg atgatgtcaa tgaatttgca aaaaatctcc tttctgctaa gagagaattg
    24841 acatattgtt ctatttgtgg acgtttgaca gacgacgatc cttgttctat ctgtactgat
    24901 ccgactcgtg accagacaac aattttagtt cttgaggata gtagagatgt ggcagccatg
    24961 gaaaatatcc aagaatacca tggactctat catgtcctgc atggcctcat ttctcctatg
    25021 aatggtatca gtccggacga tatcaatctc aagagcctta tgactcgtct tatggatagt
    25081 gaggtttcag aagtgattgt ggcgactaat gctacagcgg atggtgaagc gacttccatg
    25141 tatctttcac gtttgctcaa gccggctggt atcaaggtta cgcgtctagc acgaggtctc
    25201 gctgtgggag cggacattga gtatgcggac gaagtgacac tcttacgagc gattgaaaat
    25261 cggacagagt tgtaagtgta ggcaaattta cgaactccct tcatttataa aaaatcaaag
    25321 aggctgaaaa tcgttcctat cggcctcttt ttgtatagtg tgatgagtag gatcgggttc
    25381 aagttttaaa aaaccaagca aatatgatat actaaagagc gagtattcta gtagaattag
    25441 gacaaataat atgaaacaaa cgattattct tttatatggt ggacggagtg cggaacgcga
    25501 agtctctgtc ctttcagctg agagtgtcat gcgtgcggtc aattacgacc gtttcacagt
    25561 caagactttc tttatcagtc agtcaggtga ctttatcaaa acacaggaat ttagtcatgc
    25621 tccggggcaa gaagaccgtc tcatgaccaa tgaaaccatt gattgggata agaaagttgc
    25681 accaagtgct atctacgaag aaggtgcagt ggtctttcca gtccttcacg ggccaatggg
    25741 agaagatggc tctgttcaag gattcttgga agttttgaaa atgccttacg ttggttgcaa
    25801 cattttgtca tcaagtcttg ccatggataa aatcacgact aagcgtgttc tggaatctgc
    25861 tggtattgcc caagttcctt atgtggctat cgttgaaggc gatgatgtga ctgctaaaat
    25921 cgctgaagtg gaagaaaaat tggcttatcc agtcttcact aagccgtcaa acatggggtc
    25981 tagtgtcggt atttctaagt ctgaaaacca agaagaactc cgtcaagcct taaaacttgc
    26041 cttccgatat gacagccgtg tcttggttga gcaaggagtg aatgcccgtg aaattgaggt
    26101 tggcctcttg ggtaactacg atgtcaagag cacgctacct ggagaagttg tcaaggacgt
    26161 tgccttttat gactacgatg ccaagtatat tgataacaag attactatgg atattcctgc
    26221 caaaatcagt gatgatgtgg tggctgtcat gcgtcaaaat gcagaaacag ccttccgtgc
    26281 cattggtggc cttggtctat ctcgttgcga tttcttctat acagataagg gagagatttt
    26341 tctcaacgag ctcaatacca tgccaggttt tacccagtgg tctatgtacc cactactttg
    26401 ggacaatatg gggatcagct acccagaact aatcgagcgt ttggttgacc ttgccaagga
    26461 aagctttgac aagcgcgaag cgcatttgat ataaaatgaa agagagggta gaagccagaa
    26521 ccatcactgc acggtgacta gagttctcgg acttcagccc tttttaaagg agtagaaatg
    26581 aaattaacaa tccatgaaat tgcccaagtt gttggagcca aaaatgatat cagtatcttt
    26641 gaggacaccc agttagaaaa agctgagttt gatagtcgtt tgattggaac tggagattta
    26701 tttgtgccac ttaaaggtgc gcgtgatggc catgacttta ttgaaacagc ctttgaaaat
    26761 ggtgcagcag taaccttgtc tgagaaagag gtctcaaatc atccttacat tttagtagat
    26821 gatgttttga cagcctttca atccctagca tcctactatc ttgaaaaaac gactgttgat
    26881 gtctttgctg ttacaggttc aaatggcaag acaacgacta aggatatgtt ggcgcattta
    26941 ctgtcaacaa gatacaagac ctacaaaaca caaggcaatt acaataatga gattggcctt
    27001 ccttacacag ttctccacat gcctgaagga acagaaaagt tggtcttgga gatggggcag
    27061 gaccacttgg gagatattca tctcttgtct gaattggctc gtccaaaaac agccatcgtg
    27121 accttggttg gagaagctca tttggccttt ttcaaagatc gttctgagat tgctaaagga
    27181 aaaatgcaaa ttgcagacgg aatggcttca ggttccttgc ttttaacgcc ggctgaccct
    27241 atcgtagagg actatttgcc aactgataaa aaggtggtcc gttttgggca aggggcagag
    27301 ttggaaatca cagacttggt tgagcgtaag gacagtctga cctttaaggc taatttcttg
    27361 gaacaagtcc ttgatttgcc agtaactggc aagtacaatg cgacaaatgc tatgattgca
    27421 tcctatgttg ccttgcaaga aggagtttca gaggagcaaa ttcatcaggc cttccaaggt
    27481 cttgaattga cgcgtaatcg tactgagtgg aagaaagcag ccaatggagc agatatcctg
    27541 tcagacgtat ataatgccaa tccaactgct atgaagctga ttttagagac tttctctgcc
    27601 attccagcca atgaaggtgg caagaaaatt gcagtgttgg cggatatgaa ggagcttggt
    27661 gaccagtcta ttcaactcca taaccagatg attttgagcc tttctccaga tgtgcttgat
    27721 accgttattt tctatggaga aaatattgct gaattagccc aattggctag tcaaatgttc
    27781 ccaataggcc acgtttacta cttcaagaaa acagaagacc aagaccaatt tgaagaccta
    27841 gtcaagcagg tcaaagaaag ccttggagtc cacgaccaaa tcctgctcaa aggttctaac
    27901 tctatgaatc tagccaaatt ggtagaaagt ttagaaaatg aagccaagtg attttgttaa
    27961 gtatctgcaa agaatgattg cccttacaga tactggctta acctttacaa aggatccttt
    28021 tgaccgtgag cgctacgagg acttgcgaag tctgttatct gaaatgttga atcagggatc
    28081 agacctggat gtagaagaag tagcagaagt cttgaaacca acttcagctt atgcgactcc
    28141 cttaatggac gtccgtgctt ggattgttga ggatgagaag atttgtctgg ttaggggaca
    28201 aggagaggat agttgggctt tgccaggagg ctttggtgaa gtcggctatt ctccaactga
    28261 aaatattctc aaggaaattg aagaagaaac cggttttaaa gccaaagttg aaagactgct
    28321 agctgttttt gataccaatc gtttccaact acagagcaaa caatatgcaa agtttgtttt
    28381 tgaatgtaag cttctcgatg gacaattcca agaaaatcaa gaaatcgctg accttcaatt
    28441 ttttgcaatt gaccaactgc cgaatttatc tgaaaaacgc attaccaagg agcaaatcga
    28501 gattctttgg caggtttatc aaggtcagag ggagcaatat cttgactaag aagatgatta
    28561 tcgtatttct aaatccattt ttgacaacta gcatggtata ataatatgca ggaaaatttt
    28621 gaattatgag gaagactaga tgaatttatg ggatattttc tttacgactc aggcaaccga
    28681 gccgcccaaa tttgaccttt tttggtatgt tagcctattt acgctcttag ccttaacctt
    28741 ttatacagcc catcgctatc gtgaaaagaa ggtttaccaa cgatttttcc aaatcttgca
    28801 gactgttcag ttaatccttc tttatggttg gtactgggtt aatcatatgc cactgtcaga
    28861 aagcctaccc ttttaccatt gccgtatggc tatgtttgtg gtactcttgc ttcctggtca
    28921 gtccaaatat aaacaatact ttgcattatt gggaacattt gggacattag cagcctttgt
    28981 ttatccagtg ccagatgctt acccttttcc acatattacc attttatcct ttatctttgg
    29041 tcatttagca ctcttgggga actctctagt ttatctattg agacagtata atgcgcgatt
    29101 gctggatgtg aagggaattt ttctcatgac ctttgcccta aatgccttga tttttgtggt
    29161 caatttggtg acaggtggcg attacggatt tttgacaaaa ccgccattgg ttggggatca
    29221 cggtctagta gctaattatt tacttgtttc aattgtgctg gtagctacta tcagtttgac
    29281 taagaaaatc ttagaattct ttttagctca agaagcagaa aaaatgattg caaaggaagc
    29341 ttaacacaga gctttctttt ttgctcttag agagttttta caagcagctt ataaaataag
    29401 aatttctgaa tagacaaact caaaaaatgg ctgggaaatt taggaaaaaa gcaagcacga
    29461 ttaaattttt tgtgttataa tattttgtga atagctatgc ctatgtttag ctatggaata
    29521 atacgaagtg cgaaacttgg aagatagaga ggaagcgatg taatggctag agaaggcttt
    29581 tttacaggtc tagatattgg aacaagctct gtcaaggtgc ttgtggccga gcagagaaat
    29641 ggtgaattaa atgtaattgg cgtgagtaat gccaaaagta aaggtgtaaa ggatggaatt
    29701 attgttgata ttgatgcagc agcaactgct atcaagtcag ccatttccca agcggaagaa
    29761 aaggcaggca tttcgattaa atcagtaaat gtcggcttgc ctggtaatct tttgcaggta
    29821 gaaccaactc aggggatgat tccagtaaca tctgatacta aggaaattac ggatcaagat
    29881 gttgaaaatg ttgtcaaatc agctttgaca aagagtatga cacctgaccg tgaagtcatt
    29941 acctttattc ctgaagaatt tattgtggat ggtttccaag ggattcgtga cccacgtggc
    30001 atgatggggg ttcgccttga aatgcgtggt ttgctttata caggacctcg tactatcttg
    30061 cacaatttgc gtaagacggt tgagcgtgca ggtgttcagg ttgaaaatgt tatcatttca
    30121 ccactagcaa tggttcaatc tgttttgaac gaaggggaac gtgaatttgg tgctacagtg
    30181 attgatatgg gggcaggtca aacgactgtc gctacaatcc gtaatcaaga actccagttc
    30241 acacatattc tccaagaagg tggagattat gcaactaaag atatctccaa ggttttgaaa
    30301 acctctcgca aattagcgga aggcttgaaa ctgaattacg gggaagccta tccgcctctt
    30361 gcaagcaaag aaaccttcca agtagaggtt attggagaag tagaagcagt cgaagtgacg
    30421 gaagcctact tgtcagaaat tatttctgca cgaatcaagc acatccttga acaaatcaag
    30481 caagaattag atagaaggcg tctattggac ctccctggtg gtattgtctt aatcggtgga
    30541 aatgccattt taccaggtat ggttgagctt gctcaggaag tctttggcgt ccgtgtcaag
    30601 ctttatgttc caaatcaagt tggtatccgt aatccagcct ttgcgcatgt gattagttta
    30661 tcagaatttg cgggtcaatt aacagaagtt aatcttttgg ctcagggagc gataaaaggt
    30721 gagaatgact taagtcatca gccaattagt tttggtggga tgctgcaaaa aacagctcag
    30781 tttgtacaat caacgcctgt tcaaccagct cctgctccag aagtagagcc ggtggcgcct
    30841 acagaaccaa tggcggattt ccaacaagct tcacaaaata aaccgaaatt agcagatcgt
    30901 ttccgtggct tgatcggaag catgtttgac gaataaagag gaaaaataaa ttatgacatt
    30961 ttcatttgat acagctgctg ctcaaggggc agtgattaaa gtaattggtg tcggtggagg
    31021 tggtggcaat gccatcaacc gtatggtcga cgaaggtgtt acaggcgtag aatttatcgc
    31081 agcaaacaca gatgtacaag cattgagtag tacaaaagct gagactgtta ttcagttggg
    31141 acctaaattg actcgtggtt tgggtgcagg aggtcaacct gaggttggtc gtaaagccgc
    31201 tgaagaaagc gaagaaacac tgacggaagc tattagtggt gccgatatgg tcttcatcac
    31261 tgctggtatg ggaggaggct ctggaactgg agctgctcct gttattgctc gtatcgccaa
    31321 agatttaggt gcgcttacag ttggtgttgt aacacgtccc tttggttttg aaggaagtaa
    31381 gcgtggacaa tttgctgtag aaggaatcaa tcaacttcgt gagcatgtag acactctatt
    31441 gattatctca aacaacaatt tgcttgaaat tgttgataag aaaacaccgc ttttggaggc
    31501 tcttagcgaa gcggataacg ttcttcgtca aggtgttcaa gggattaccg atttgattac
    31561 caatccagga ttgattaacc ttgactttgc cgatgtgaaa acggtaatgg caaacaaagg
    31621 gaatgctctt atgggtattg gtatcggtag tggagaagaa cgtgtggtag aagcggcacg
    31681 taaggcaatc tattcaccac ttcttgaaac aactattgac ggtgctgagg atgttatcgt
    31741 caacgttact ggtggtcttg acttaacctt gattgaggca gaagaggctt cacaaattgt
    31801 aaaccaggca gcaggtcaag gagtgaacat ctggctcggt acttcaattg atgaaagtat
    31861 gcgtgatgaa attcgtgtaa cagttgttgc aacgggtgtt cgtcaagacc gcgtagaaaa
    31921 ggttgtggct ccacaagcta gatctgctac taactaccgt gagacagtga aaccagctca
    31981 ttcacatggc tttgatcgtc attttgatat ggcagaaaca gttgaattgc caaaacaaaa
    32041 tccacgtcgt ttggaaccaa ctcaggcatc tgcttttggt gattgggatc ttcgccgtga
    32101 atcgattgtt cgtacaacag attcagtcgt ttctccagtc gagcgctttg aagccccaat
    32161 ttcacaagat gaagatgaat tggatacacc tccatttttc aaaaatcgtt aagtaaatga
    32221 atgtaaaaga aaatacagaa cttgtttttc gagaagttgc agaggctagt ctgagtgctc
    32281 atcgagagag tggttcggtc tctgtcattg cagttaccaa gtatgtagat gtaccgacag
    32341 cggaagcctt gcttccgcta ggtgttcatc atatcggtga aaatcgtgta gataagtttc
    32401 tggaaaaata tgaagcttta aaagatcgag atgtgacttg gcatttgatt ggtaccttgc
    32461 aaagacgtaa ggtgaaagat gtcattcaat acgttgatta tttccatgca ttggactcag
    32521 taaagctagc aggggaaatt caaaaaagaa gtgaccgagt catcaagtgt ttccttcaag
    32581 taaatatttc taaagaagaa agcaaacacg gtttttcgag agaggaactg ctggaaatct
    32641 tgccagagtt agccagacta gataagattg aatatgttgg tttaatgacg atggcacctt
    32701 ttgaggctag cagtgagcag ttgaaagaga ttttcaaggc ggcccaagat ttacaaagag
    32761 aaattcaaga gaaacaaatt ccaaatatgc ctatgaccga gttaagtatg ggaatgagtc
    32821 gtgattataa agaagcgatt caattcggtt ccacttttgt tcgtataggt acatcatttt
    32881 ttaagtagga gagaaccatg tctttaaaag atagattcga tagatttata gattatttta
    32941 cggaggatga ggattcaagt ctcccttatg aaaaaagaga tgagcctgtg tttactccag
    33001 taaattcttc acaggaaccg gctctcccaa tgaatcaacc ttcacagtcg gctggtacaa
    33061 aagagaacaa tatcaccaga cttcatgcaa gacaacagga attggcaaat cagagtcagc
    33121 gtgcaacgga taaggtcatt atagatgttc gttatcctag aaaatatgag gatgcaacag
    33181 aaattgttga tttattggca ggaaacgaaa gtatcttgat tgattttcag tatatgacag
    33241 aggtgcaggc tcgtcgttgt ttggactatt tggatggggc ttgtcatgtt ttagctggaa
    33301 atttgaaaaa ggtagcttct accatgtatt tgttgacacc agtgaacgtt attgtaaatg
    33361 ttgaagatat ccgtttacca gatgaagatc aacagggtga gttcggtttt gatatgaagc
    33421 gaaatagagt acgataatga tttttttaat tcgtatgatt tataatgcag tggatattta
    33481 ctccctaatt ttggtagcct tcgctgtcat gtcttggttt ccaggtgcct acgaatccag
    33541 tttaggtcgt tggattgtag cgttggtaaa accagtgctt gctcccttgc aacgcctgcc
    33601 tttacagata gcgggtcttg atttatctgt ttgggttgcg attgttttgg ttcgattttt
    33661 aggagaaaac ctagtgcgtt ttctggcgat gataggatga ataaagggat ttatcagcat
    33721 ttctccatag aagatcgtcc atttcttgac aagggaatgg aatggataaa gaaggtagaa
    33781 gatagctatg ctcctttttt aactcctttt atcaatcctc atcaggagaa gctattaaag
    33841 attttggcca aaacctatgg tcttgcttgt agcagtagtg gggaattcgt ctcgagtgag
    33901 tatgttcgag ttttattata cccagattat ttccaaccag agttttcaga ttttgaaata
    33961 tctctccaga aaattgtgta ttccaataaa tttgaacatt taacgcatgc taagatttta
    34021 gggacagtca tcaatcaatt agggattgaa cggaaacttt ttggagatat cctagtagat
    34081 gaagaacggg cgcagattat gattaatcag cagtttcttc ttctctttca agatggacta
    34141 aagaaaattg gtcgtatacc tgtttcgctg gaggaacgtc ctttcaccga gaaaatagat
    34201 aagctagaac agtatcgaga actggattta tctgtgtcta gttttcgatt agatgttctt
    34261 ttatcaaatg ttttgaaact atctaggaat caagcaaacc agttgattga aaagaaactt
    34321 gtccaagtaa attatcatgt ggtagacaaa tcagattaca ctgttcaagt tggcgacttg
    34381 attagtgtga gaaaatttgg tcgcttgaga ttacttcaag ataagggaca aacgaaaaaa
    34441 gagaagaaaa aaataaccgt ccagttatta ttaaataagt gaggaataga atgccaatta
    34501 catcattaga aataaaggac aagacttttg gaactcgatt cagaggtttt gatccagaag
    34561 aagtcgatga atttttagat attgtggttc gtgattacga agatcttgtg cgtgcgaatc
    34621 atgataaaaa tttgcgtatt aagagtttag aagagcgttt gtcttacttt gatgaaataa
    34681 aagattcatt gagccagtct gtattgattg ctcaggatac agctgagaga gtgaaacagg
    34741 cggcgcatga acgttcaaac aatatcattc atcaagcaga gcaagatgcg caacgcttgt
    34801 tggaagaagc taaatataag gcaaacgaga ttcttcgtca agcaactgat aatgctaaga
    34861 aagtcgctgt tgaaacagaa gaattgaaga acaagagccg tgtcttccac caacgtctca
    34921 aatctacaat tgagagtcag ttggctattg ttgaatcttc agattgggaa gatattctcc
    34981 gtccaacagc tacttatctt caaaccagtg atgaagcctt taaagaagtg gttagcgaag
    35041 tacttggaga accgattcca gctccaattg aagaagaacc aattgatatg acacgtcagt
    35101 tctctcaagc agaaatggaa gaattacaag ctcgtattga ggtagccgat aaagaattgt
    35161 ctgaatttga agctcagatt aaacaggaag tggaaactcc aactcctgta gtgagtcctc
    35221 aagttgaaga agagcctctg ctcatccagt tggcccaatg tatgaagaac cagaagtagc
    35281 tccagtgcat ccgacaggtc caacaccagc tacagaaact gttgattcag caccgggatt
    35341 tgaagcaccg caagaatctg ttacaatttt ataagaaata ttctgagaac aatatcttat
    35401 ccttatattc ccagcgagca ggagatggtg tgagtcctgc attccctatc gataagatta
    35461 tcctctcaaa aactcaagtc tgaagctagt aagatttgac gttccccacg ttacgggata
    35521 agagggagaa agactaaatc tttttccgaa taaaggtggt accacgattt tcgtcctttt
    35581 tggaagtcgt ggtttttaat ttgttattat ttataaagga gataccatga aactcaaaga
    35641 cacccttaat cttgggaaaa ctgaattccc aatgcgtgca ggccttccta ccaaagagcc
    35701 agtttggcaa aaggaatggg aagatgcaaa actttatcaa cgtcgtcaag aattgaacca
    35761 aggaaaacct catttcacct tgcatgatgg ccctccatac gctaacggaa atatccacgt
    35821 tggacatgct atgaacaaga tttcaaaaga tatcattgtt cgttctaagt ctatgtcagg
    35881 attttacgca ccatttattc ctggttggga tactcatggt ctgccaatcg agcaagtctt
    35941 gtcaaaacaa ggtgtcaaac gtaaagaaat ggacttggtt gagtacttga aactttgccg
    36001 tgagtacgct ctttctcaag tagataaaca acgtgaagat tttaaacgtt tgggtgtttc
    36061 tggtgactgg gaaaatccat atgtgacctt gactcctgac tatgaagcag cccaaatccg
    36121 tgtctttggt gagatggcta ataagggtta tatctaccgt ggtgccaagc cagtttactg
    36181 gtcatggtca tctgagtcag cccttgctga agcagagatt gaataccatg acttggtttc
    36241 aacttccctt tactatgcca acaaggtaaa agatggcaaa ggagttctag atacagatac
    36301 ttatatcgtt gtctggacaa cgactccatt taccatcaca gcttctcgtg gtttgacggt
    36361 tggtgcagat attgattacg ttttggttca acctgctggt gaagctcgta agtttgtcgt
    36421 tgctgctgaa ttattgacta gcttgtctga gaaatttggc tgggctgatg ttcaagtttt
    36481 ggaaacttac cgtggccaag aactcaacca catcgtaaca gaacacccat gggatacagc
    36541 tgtagaagag ttggtaattc ttggtgacca cgttacgact gactctggta caggtattgt
    36601 ccatacagcc cctggttttg gtgaggacga ttacaatgtt ggtattgcta ataatcttga
    36661 agtcgcagtg actgttgatg aacgtggtat catgatgaag aatgctggtc ctgaatttga
    36721 aggtcaattc tatgaaaagg tagttccaac tgttattgaa aaacttggta acctcctttt
    36781 tgcccaagaa gaaatctctc actcatatcc atttgactgg cgtactaaga aaccaatcat
    36841 ctggcgtgca gttccacaat ggtttgcctc agtttctaaa ttccgtcaag aaatcttgga
    36901 cgaaattgaa aaagtgaaat tccactcaga atggggtaaa gtccgtcttt acaatatgat
    36961 ccgtgaccgt ggtgactggg ttatctctcg tcaacgtgct tggggtgttc cacttcctat
    37021 cttctacgct gaagatggta cagctatcat ggtagctgaa actattgaac acgtagctca
    37081 actttttgaa gaacatggtt caagcatttg gtgggaacgt gatgccaaag acctcttgcc
    37141 agaaggattt actcatccag gttcaccaaa cggcgagttc aaaaaagaaa ctgatatcat
    37201 ggacgtttgg tttgactcag gttcatcatg gaatggagtg gtggtaaacc gtcctgactt
    37261 gacttaccca gccgaccttt acctagaagg ttctgaccaa taccgtggtt ggtttaactc
    37321 atcacttatc acatctgttg ccaaccatgg cgtagcacct tacaaacaaa tcttgtcaca
    37381 aggttttgcc cttgatggta aaggtgagaa gatgtctaaa tctcttggaa atactattgc
    37441 tccaagcgat gttgaaaaac aattcggtgc tgaaatcttg cgtctctggg taacaagtgt
    37501 tgactcaagt aatgacgtgc gtatctctat ggatatcttg agccaagttt ctgaaactta
    37561 ccgtaagatt cgtaacactc ttcgtttctt gattgccaat acatctgact ttaacccagc
    37621 tcaagataca gtcgcttacg atgagcttcg ttcagttgat aagtacatga cgattcgctt
    37681 taaccagctt gtcaagacca ttcgtgatgc ctatgcagac tttgaattct tgacgatcta
    37741 caaggccttg gtgaacttta tcaacgttga cttgtcagcc ttctaccttg attttgccaa
    37801 agatgttgtt tacattgaag gtgccaaatc actggaacgc cgtcaaatgc agactgtctt
    37861 ctatgacatt cttgtcaaaa tcaccaaact cttgacacca atccttcctc acactgcgga
    37921 agaaatctgg tcatatcttg agtttgaaac agaagacttc gtccaattgt cagaattacc
    37981 agaagttcaa acttttgcta accaagaaga aatcttggat acatgggcag ccttcatgga
    38041 ctttcgtgga caagcacaaa aagccttgga agaagctcgt aatgcaaaag ttatcggtaa
    38101 atcacttgaa gcacacttga cagtttatcc aaatgaagtt gtgaaaactc tactcgaagc
    38161 agtaaacagc aatgtagctc aacttttgat cgtgtctgag ttgaccatcg tagaaggacc
    38221 agctccggaa gctgccctta gcttcgaaga tgtagccttc acagttgaac gtgctactgg
    38281 tgaagtatgt gaccgttgcc gtcgtatcga cccaacaaca gcagaacgca gctaccaggc
    38341 agttatctgt gaccactgtg caagcatcgt agaagaaaac tttgcggaag cagtcgcaga
    38401 aggatttgaa gagaaataag attgaaaagt ctaggcaaaa ttcaatttga gaagaaaaga
    38461 caactaattt tatagtctat taaacgcatt gtatcacgtt tttgaatacc tgatatgatg
    38521 cgttttttat ttattttaaa aatttgcgag gtatgacttt ttatactcaa caagaatcaa
    38581 agagaaactt agcaatctaa cagtagtaag a
//
LOCUS       DAVLZS010000018        36323 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLZS010000018 DAVLZS010000000
VERSION     DAVLZS010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36323
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.018"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            261..689
                     /locus_tag="VYO88_000965"
     CDS             261..689
                     /locus_tag="VYO88_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719085.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVDLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            768..1355
                     /locus_tag="VYO88_000966"
     CDS             768..1355
                     /locus_tag="VYO88_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV1719086.1"
                     /translation="MGGNPPIKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            1607..1885
                     /locus_tag="VYO88_000967"
     CDS             1607..1885
                     /locus_tag="VYO88_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEV1719087.1"
                     /translation="MEKVASLGVPMCKPISIELCDDEVHSLHEWIDGRDAIDSILTYS
                     ENQQYTYGVEAGKILRKIHTIPATEVCEDWEIFFYLKIDDKISNEMIW"
     gene            1990..2292
                     /locus_tag="VYO88_000968"
                     /pseudo
     CDS             1990..2292
                     /locus_tag="VYO88_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2448..3677
                     /locus_tag="VYO88_000969"
     CDS             2448..3677
                     /locus_tag="VYO88_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1719088.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            3697..6393
                     /gene="ppc"
                     /locus_tag="VYO88_000970"
     CDS             3697..6393
                     /gene="ppc"
                     /locus_tag="VYO88_000970"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1719089.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIHQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAVMDQVVDRS
                     YDVYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    6476..6693
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6806..7810
                     /locus_tag="VYO88_000971"
     CDS             6806..7810
                     /locus_tag="VYO88_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1719090.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7879..8745
                     /locus_tag="VYO88_000972"
     CDS             7879..8745
                     /locus_tag="VYO88_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1719091.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGYLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTGYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8742..9500
                     /locus_tag="VYO88_000973"
     CDS             8742..9500
                     /locus_tag="VYO88_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719092.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            9590..11350
                     /gene="dnaG"
                     /locus_tag="VYO88_000974"
     CDS             9590..11350
                     /gene="dnaG"
                     /locus_tag="VYO88_000974"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1719093.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEEFERLISQKRRME"
     gene            11353..12462
                     /gene="rpoD"
                     /locus_tag="VYO88_000975"
     CDS             11353..12462
                     /gene="rpoD"
                     /locus_tag="VYO88_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1719094.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            12476..12805
                     /locus_tag="VYO88_000976"
     CDS             12476..12805
                     /locus_tag="VYO88_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1719095.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12920..13963
                     /gene="cpoA"
                     /locus_tag="VYO88_000977"
     CDS             12920..13963
                     /gene="cpoA"
                     /locus_tag="VYO88_000977"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1719096.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            13979..15304
                     /locus_tag="VYO88_000978"
     CDS             13979..15304
                     /locus_tag="VYO88_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1719097.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            15335..15511
                     /locus_tag="VYO88_000979"
     CDS             15335..15511
                     /locus_tag="VYO88_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1719098.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            15570..15704
                     /locus_tag="VYO88_000980"
     CDS             15570..15704
                     /locus_tag="VYO88_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1719099.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15768..17078
                     /gene="obgE"
                     /locus_tag="VYO88_000981"
     CDS             15768..17078
                     /gene="obgE"
                     /locus_tag="VYO88_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1719100.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            17088..17246
                     /locus_tag="VYO88_000982"
     CDS             17088..17246
                     /locus_tag="VYO88_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719101.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            18389..19648
                     /locus_tag="VYO88_000983"
     CDS             18389..19648
                     /locus_tag="VYO88_000983"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1719102.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAKGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            19664..20215
                     /locus_tag="VYO88_000984"
     CDS             19664..20215
                     /locus_tag="VYO88_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719103.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            20208..21485
                     /locus_tag="VYO88_000985"
     CDS             20208..21485
                     /locus_tag="VYO88_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1719104.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            21501..22361
                     /locus_tag="VYO88_000986"
     CDS             21501..22361
                     /locus_tag="VYO88_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1719105.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            22741..23544
                     /locus_tag="VYO88_000987"
                     /pseudo
     CDS             22741..23544
                     /locus_tag="VYO88_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            23735..26026
                     /gene="pcrA"
                     /locus_tag="VYO88_000988"
     CDS             23735..26026
                     /gene="pcrA"
                     /locus_tag="VYO88_000988"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1719106.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            26069..26749
                     /gene="radC"
                     /locus_tag="VYO88_000989"
     CDS             26069..26749
                     /gene="radC"
                     /locus_tag="VYO88_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1719107.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(26746..27435)
                     /locus_tag="VYO88_000990"
     CDS             complement(26746..27435)
                     /locus_tag="VYO88_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1719108.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(27453..28094)
                     /locus_tag="VYO88_000991"
     CDS             complement(27453..28094)
                     /locus_tag="VYO88_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1719109.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(28177..28392)
                     /locus_tag="VYO88_000992"
     CDS             complement(28177..28392)
                     /locus_tag="VYO88_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1719110.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(28400..28747)
                     /locus_tag="VYO88_000993"
     CDS             complement(28400..28747)
                     /locus_tag="VYO88_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1719111.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(28752..29867)
                     /locus_tag="VYO88_000994"
     CDS             complement(28752..29867)
                     /locus_tag="VYO88_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1719112.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(29877..30836)
                     /locus_tag="VYO88_000995"
     CDS             complement(29877..30836)
                     /locus_tag="VYO88_000995"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1719113.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(30949..31518)
                     /locus_tag="VYO88_000996"
     CDS             complement(30949..31518)
                     /locus_tag="VYO88_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1719114.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            31646..32317
                     /locus_tag="VYO88_000997"
     CDS             31646..32317
                     /locus_tag="VYO88_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1719115.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            32301..33119
                     /locus_tag="VYO88_000998"
     CDS             32301..33119
                     /locus_tag="VYO88_000998"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1719116.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            33116..34012
                     /locus_tag="VYO88_000999"
     CDS             33116..34012
                     /locus_tag="VYO88_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1719117.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            34056..35030
                     /gene="pta"
                     /locus_tag="VYO88_001000"
     CDS             34056..35030
                     /gene="pta"
                     /locus_tag="VYO88_001000"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1719118.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(35291..36323)
                     /locus_tag="VYO88_001001"
                     /pseudo
     CDS             complement(35291..36323)
                     /locus_tag="VYO88_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        11070 a         6396 c         8008 g        10849 t
ORIGIN      
        1 ttgaggcagt atcactgctt gtacaagctg aggcatcagc gaagtagaag taaatgatct
       61 cccatacgat aggactcgta gaatgaggag ggaaaccgac gaaatgataa ggtaagtccg
      121 aaccgctgag tgcgtggctc tgctcttccg atctgagaca gtcgaaaagt agaaggggat
      181 ggtattggta tcaatcaatg agtaacaaag tatcagcatg attcgaaaca tttacttgta
      241 atttgcggag gaacatcaat atggatggaa taacaaaaga ttttataaaa acggctaaac
      301 taatgaaaca attatggccc caattgaccg ataaagaagc tattgatgaa gtaaaaaaat
      361 atacgaatgg caaaaatact gcaatcttta ctgaagttga aggtgacaca attgtagatc
      421 tagcactatg ttcactcaga tttgattatg ttgaaggttg taaatatagt cctgttggat
      481 tcttagaagg gattattgtt gacgaggaat atcgtttaaa ggatattgct aaaaatctct
      541 gtacaaaatg tgaggaatgg gcgaaaaata aaggatgtaa ggaatttgca agtgactgta
      601 ctttaacgaa tacggattct ataagatttc atctcaatat tggatttcag gaggcaaata
      661 gaattattca ttttaagaaa aaattataat ttagaaacgt gaataaactt gtttaaactt
      721 tatgtatctt tagaaagtgt gttaacttga aagaacaaat ttttttgatg ggtgggaatc
      781 ccccaataaa gaaatatagt attgttgata aaattgtatt atcaaccaag attaaaagaa
      841 ttatcatttt tacagttttt cgagaaaatt gggaaccgta catgaaaaag tacacggaag
      901 tttttcaaag tcaatttcct aatctaaaca ttgattactt gctcctggac actgagcaga
      961 ttgatcttga tagctatcta gatgctgaca taattatcat cggtggtgga aatacggaaa
     1021 aatatattgc tacttatgtt aatcaggagt tcaaaagtta tatcgatcat atgcttaata
     1081 aagaggcaaa aattatagga ttttctgcag gagccctact attaggagaa aaagtctatg
     1141 tctcacctaa tgataattca gatcatcaga taaagataaa aaatggatta ggactcttta
     1201 gtcagttttt aattagtgtc cattatgatt cctggaatga taaagcaaat aaggatagag
     1261 ctgaagaact cgttaatgtt cccataattc cactaaatga tcattcttgt cttgtattgg
     1321 ataaacttgg aaacatcata gagaaaattg actaactttc ataatgtaaa aatggatcta
     1381 ggaaataaaa gtgtagacga actggatagg ttactagtga aaactgcaaa aagtgttgta
     1441 aagtgaatcg gagtgtgctt gatggatttt agtagtaaga tagccataaa taaaggctgg
     1501 tcagatggat aaaaaatatt gtgtgacagt tcaaaatcag taaacatatt tcttgcgtgt
     1561 ttctgataag tcgaagttag attataaaaa aattgaattt gatacgatgg agaaagtagc
     1621 ttctcttgga gttccgatgt gtaaaccaat tagcattgaa ctctgcgatg acgaagtaca
     1681 ttctttacac gaatggatag acggaagaga tgcaatagat agcattttaa cttattcaga
     1741 aaaccaacaa tacacatatg gtgtagaagc aggaaagata cttagaaaga ttcatacaat
     1801 tcctgctaca gaagtttgtg aagattggga aatctttttt tatctaaaaa ttgatgataa
     1861 aatctccaac gaaatgatat ggtaagtccg aaacgctcag tgtgtaagct tgttgctaaa
     1921 agcgtaaaaa ccttggaacg aaaggaataa tagacttcct gcgaaacaaa aatacaatac
     1981 aataaaacta tggatgatga agcaagtaaa caattgagcg atagccgttt caagatcctt
     2041 gtaggtgttc agcgcacgac ttttgaagag atgttagctg tgttaaaaac agcttatcaa
     2101 cgtaaacgcg caaaaggtgg acgaaaaagc aaattaagcc tagacgatct ccttatggta
     2161 actattcaat acatgcgaga atagagcact tatgaacaaa ttgcggctga ttttggcatt
     2221 cacgaaagca acttaatccg tcggagtcaa tgggttgaag caactcttat tcaaaatggt
     2281 tttacgattt caaattctgc cttaattctg taaaaacagt aaaattcgaa ggattgtaag
     2341 gtaagagttt ttttctttct gaaaaaatgg tataatagca atcaaaacta gaaaataaaa
     2401 cggaatttgg aacagatttg tctgtatcct agtagagtgg tgatactatg aagattagta
     2461 agaggcactt attaaattat tccatcttga ttccctactt gcttttatct attttgggct
     2521 tgattgtggt ctattcgacc accagtgcta ttttaattga agaaggcaag agcgccttgc
     2581 agttggttcg aaaccaagga atcttttgga ttgttagttt gatactgatt gccttaattt
     2641 ataaattgag actagatttt ttgagaaatg agcgactaat cattttagtt atattaatag
     2701 aaatgctttt attgttcttg gctcgtttta ttggtatttc cgtaaacggg gcatacggtt
     2761 ggatttcggt tgcaggaata actattcagc cagctgagta cttaaaaatc attattattt
     2821 ggtatttagc tcaccgattc tccaaacagc aagaagaaat agctacttat gattttcaag
     2881 ttttgactca aaatcaatgg cttccccgtg cttttaatga ttggcgattc gttctcctag
     2941 ttctgattgg aagtttggga attttccctg atttaggaaa tgcgactatt ttagtcttgg
     3001 tttccttgat tatgtataca gttagtggaa tcgcttatcg ctggttttca accattctgg
     3061 cgctcgtatc tgccgcttct gtctttgtct tgaccactat cagcctaatc ggtgttgaga
     3121 ccttttcaaa aattccagta tttggctatg tagccaagcg ctttagtgcc ttttttaatc
     3181 cttttgccga tcgtgctgat gcaggtcacc agttagctaa ttcttatttt gccatggtca
     3241 atggtggttg gtttggtcta ggtcttggaa actcgattga aaaacgaggt tatttgccag
     3301 aagctcatac agactttgtc ttttctatcg tgattgaaga atttggcttt gttggtgcca
     3361 gtcttatttt agctctcttg tttttcatga ttttgcggat tatcttggtc ggtatccgag
     3421 cggagaatcc tttcaatgcc atggttgcac tcggtgtcgg agggatgatg ttggttcagg
     3481 tatttgtcaa tatcggaggg atttcgggct tgattccatc tacaggagtg actttccctt
     3541 tcttatccca gggtggaaat agtcttctag tcttatcagt ggcagtagcc tttgtcttaa
     3601 atattgatgc cagtgaaaaa cgcgctaagt tgtaccgaga attggaaaat caaccaatga
     3661 accttctgtt gaagtaggat aaagaaagga tagtttatgt ctcttcaaaa attagaaaat
     3721 tatagtaata aaagtgttgt gcaagaagaa gtcttgattc taacagaatt actggaagat
     3781 attactaaaa atatgcttgc cccagagacc tttgaaaaaa taatacagtt gaaagaatta
     3841 tcaacgcagg aagattatca aggtctaaac cgtctagtga ctagcttatc aaatgatgaa
     3901 atggtctata tttcacgcta tttctctatc ttacctcttt tgattaatat ttcagaggat
     3961 gtggatttag cttatgaaat caatcatcaa aataatattg atcaggacta tttaggtaaa
     4021 ttatctacaa cgattaaatt ggtagcagaa aaggaaaatg ccgttgagat cctagaacac
     4081 ttgaatgttg tccctgtttt gacagcccat ccaacacaag tgcaacgcaa aagtatgttg
     4141 gatttaacaa atcatattca tagtcttttg cgtaaatacc gtgatgttaa gttggggttg
     4201 atcaataaag ataaatggta caatgatttg cgtcgttaca tcgaaattat catgcagaca
     4261 gacatgattc gtgagaaaaa attaaaagtg actaacgaaa tcacgaatgc tatggaatat
     4321 tataacagct cctttttgaa agctgtacct catttgacga cggagtataa gcgcttagcg
     4381 caagcgcatg gtctgaattt aaaacaggct aaaccaatca ccatgggtat gtggataggt
     4441 ggtgaccgtg atggaaatcc atttgttaca gcagagacct tgaagcagtc tgcactcact
     4501 caatgtgaag tcatcatgaa ctactatgat aaaaagattt accaacttta tcgtgaattt
     4561 tctctttcaa ctagcattgt caacgtcagc aagcaagtca gagaaatggc tcgtcaatcc
     4621 aaggataact cgatttaccg cgaaaaagag ctttaccgcc gtgccttgtt tgatattcaa
     4681 tcaaaaattc aggcaactaa aacctatctg attgaggatg aagaagttgg gactcgttat
     4741 gaaaccgcca atgatttcta caaggatttg attgccattc gagattctct actagagaat
     4801 aagggcgagt ccttgatttc aggtgatttt gtggaattat tgcaggcagt agagatattt
     4861 ggtttttacc tagcatcaat tgatatgcga caagactcta gcgtctatga agcctgtgtg
     4921 gcagaactct tgaaatcagc aggaattcat tctcgttata gcgagttgag cgaagaagaa
     4981 aagtgtgacc ttcttttgaa agaattagaa gaagatcccc gaattctttc tgcgactcac
     5041 gcagaaaaat cagaattatt agcaaaagaa ctagctattt ttaagacggc tcgtgttttg
     5101 aaagataagt tgggagatga tgtcatccat cagaccatca tttcacatgc aaccagcctt
     5161 tctgatatgc tagaattagc tattctgtta aaagaagtag gactggtgga tacggaaagg
     5221 gcgcgtgttc agattgttcc cctttttgaa acaattgaag acttggatca ttcagaggaa
     5281 acaatgagaa aatatctttc tcttagtctt gccaaaaaat ggattgactc acgaaataac
     5341 taccaagaaa tcatgcttgg ctactctgac agtaataaag atggcggtta cttgtcatca
     5401 tgttggaccc tctacaaggc tcaacaacaa ttgactgcta ttggagatga atttggcgtt
     5461 aaggttacct tcttccatgg tcgtggtggt actgtcggtc gtggtggtgg gccaacctat
     5521 gaagctatta catctcaacc gctcaagtct atcaaggatc gtatccgctt gacggagcag
     5581 ggtgaagtaa ttgggaataa atacggtaac aaagacgccg cttactataa ccttgaaatg
     5641 ctagtatcgg cagctattaa ccgtatgatt actcagaaga agagcgatac caatacccca
     5701 aatcgttatg aagccgttat ggatcaagta gtggaccgta gttacgatgt ctaccgtgat
     5761 ttggtctttg gtaatgagca tttctatgat tatttcttcg agtcaagtcc aatcaaggct
     5821 atttcaagtt ttaatattgg ttctcgtcca gccgctcgta agactattac tgaaatcggt
     5881 ggtttgcgtg ccatcccttg ggtattctca tggtcacaga gtcgtgttat gttccctgga
     5941 tggtacgggg ttggttcaag cttcaaggaa tttatcaata aaaatccaga gaatattgct
     6001 atcttacgag atatgtacca aaattggcct ttcttccaat cgcttctttc aaatgttgat
     6061 atggttttgt caaaatcaaa tatgaatatt gcttttgaat atgctaaact ttgtgaagac
     6121 gagcaagtta aggccatcta tgagactatt ttaaatgaat ggcaagttac taagaacgtt
     6181 atcttggcta ttgaaggaca tgacgaactc ttagctgaca atccatatct aaaagctagt
     6241 ctggattacc gtatgcctta ctttaatatt ctcaactata ttcagttaga gttgattaaa
     6301 cgccaacgtc gtggagaatt gtccagtgat caagaacgat tgattcatat caccatcaac
     6361 ggaattgcga caggattgcg taattcaggt tgataatttt caagagtgaa tgctaaaagt
     6421 gaatatcaaa aaaattctaa tagactattg acaagtagtt taaaaatgat ataatttaac
     6481 cattcagaaa agtaatcata caaacttttt agagagtctg tggtagctga aaacagataa
     6541 gtggcaatga tgaaaattgg gctgaatgct atttagaatt tgaaattata aaaattcggt
     6601 aagcacacct tacagtgcat ctcgttattg cgagactgag cgatagggaa attccctata
     6661 attgaggtgg taccgcgcat cgacgtcctc acacaagttt tttgtgtgag gatttttttg
     6721 atggaggtta gtatggaaag aaaacaatgg cgtcgcttgt ttagataagt gaaatatgtt
     6781 aaaggaaata aaaaggagaa acagaatgaa aaataaacgt ttaattggaa ttattgctgc
     6841 attagcagtc ttagtagcag gaagcttgat ttattcttca atgaataaat cagaagttca
     6901 gaataataag gatgagaaga aaataaccaa gattggtgtg cttcaatttg tgagccatcc
     6961 atcccttgat ttgatttata aagggatcca agatggactt gcagaagaag gatataaaga
     7021 tgatcaagtt aaaattgatt ttatgaactc agaaggtgac caaagtaagg ttgcgacaat
     7081 gagtaaacaa ttggttgcaa atgggaatga ccttgtggtt ggtatcgcaa caccagcagc
     7141 ccaagggttg gctagtgcaa caaaagacct accggttatc atggccgcta ttacagaccc
     7201 aattggtgct aacttggtta aagatttgaa aaaaccaggt ggcaacgtta caggggtatc
     7261 tgaccacaat ccagctcaac aacaagttga actcatcaag gctctgacac cgaatgtgaa
     7321 aacaatcgga gctctttact caagtagcga agacaattca aaaacacagg tcgaagaatt
     7381 taaggcttat gctgaaaaag caggtctgac agtggaaaca tttgcagttc cttcaacaaa
     7441 tgaaattgcc tcaactgtca ctgttatgac tagcaaggta gatgctattt gggttccaat
     7501 tgataacacc attgcatcag gatttccaac ggttgtctct agcaatcaaa gttctaagaa
     7561 accaatttat cccagtgcga cagctatggt agaagtaggt ggtttggcat cagttgtaat
     7621 tgaccaacat gaccttggtg tggcaacagg taaaatgatt gtgcaagtct tgaaaggtgc
     7681 aaaaccagcc gataccccag tcaatgtctt ttcaactggt aagtcagtca tcaataaaaa
     7741 aatagcacaa gaactaggta ttactattcc tgagtctgtt ctcaaagaag caggacaagt
     7801 catcgaataa ataaggtagg gaggaggaga ctcttcccat tttttaaaaa gatgaatata
     7861 gaaaggatta aataaaatat gattgtttcc attatttctc aaggatttgt ctgggctatt
     7921 ctaggtctgg gaatctttat gacatttagg attttaaact ttccagatat gacgacagaa
     7981 ggttccttcc ctcttggggg agctgttgct gtcactttga taaccaaagg cgtgaatcca
     8041 tttttagcga cacttgttgc tgtaggagca ggttatttgg ctggaatggc agcaggcctt
     8101 ctttatacaa aagggaagat cccaaccttg ctctcaggga ttttggtgat gacttcttgt
     8161 cactcaatca tgctcttgat tatgggacgt gcaaatttag gcctgcttgg aaccaagcaa
     8221 attcaggatg ttttgccttt tgattcggat ttgaatcaac tcttgacagg tctcatcttt
     8281 gtgagcattg ttattgctct catgctcttt ttcttggaca ctaaactcgg acaagcctat
     8341 attgctacag gggataatcc tgatatggct agaagtttcg ggattcatac tggacgcatg
     8401 gagctcatgg gcttggtctt atcaaatggt gtgattgccc ttgcaggtgc cctcattgct
     8461 cagcaagaag gctatgccga tgtgtctcga gggatcgggg ttatcgttgt ggggcttgca
     8521 agtttgatta ttggagaagt tattttcaag agtttgagct tggcagagcg tttggttact
     8581 atcgttgtag gttctatcgc ttatcaattt ttagtgtggg cagttatcgc acttggcttt
     8641 aatacaggtt accttcgttt atacagtgct ttgattttag cagtctgcct catgattcca
     8701 acatttaagc aaacaatctt gaaaggagcc aagttaagca aatgacagca attgtagaat
     8761 taaaaaatgc aaccaaaatc gttaaaaatg gctttgatga agaaaagatt attttaaatg
     8821 atgtttcctt agaaattttt gaacgggact ttatcacgat tttgggcgga aatggtgctg
     8881 gaaaatcaac tctctttaac actatagcag ggaccttatc actaactagt ggaactatcc
     8941 gtattttagg tgaagatctc actaagtttt cacccgagaa gcgtgccaag tacctgtctc
     9001 gtgtcttcca agatccaaag atggggacag ctccccgtat gacggtcgct gaaaatcttt
     9061 taatcgccaa gtttcgtggt gaaaagcgtg gattgttacc aagacgcttg actagctata
     9121 aggatgaatt tcaggcaacc attgaaaaag taggaaatgg tcttgagaaa cacttgaata
     9181 caccgattga gttcttatca ggtggacaaa gacaggcttt gagtctcttg atggcaacct
     9241 tgaagcgacc tgaattactc ctgttagatg agcatactgc tgccctggat ccaaagacta
     9301 gtgttgcttt gatggaattg acagatgaat ttgttaagaa agatcagcta acagccctta
     9361 tgattactca tcatatggaa gatgctctca aatacggcaa tcgcttgatt gtcatgaaag
     9421 aaggacggat tatccaagat ttaaaccaag aagaaaaagc aaaaatgaaa atctctgatt
     9481 attatcaact ctttgaataa agtagggaaa atgagtgaaa tggtttactt tttttctgaa
     9541 ataaagtata ctatataaag taaactatga taacatggag gtattgtgta tggttgacaa
     9601 acaagtcatt gaagaaatca aaaacaatgc caacattgtg gaagtcatag gagatgtgat
     9661 ttctttacaa aaggcaggac ggaactatct agggctctgt ccttttcatg gtgaaaaaac
     9721 accttctttc aacgttgtag aggataagca gttttaccac tgttttggtt gtggtcgttc
     9781 aggtgatgtc tttaaattca tcgaggagta ccaaggggtt acctttatgg aggctgtcca
     9841 aatcttaggt cagcgtgtcg ggattgaggt tgaaaaaccg ctttatagtg aacagaagcc
     9901 agcctcgcct caccaagctc tttatgatat gcacgaagat gcggctaaat tttaccatgc
     9961 tattctcatg acaacgacta tgggcgaaga ggccagaaat tacctttatc agcggggttt
    10021 gacagatgaa gtgcttaaac atttttggat tggtttagca cctccagaac gaaactatct
    10081 ctatcaacgt ttgtctgatc agtatcgtga agaggattta ctggattcag gcctgtttta
    10141 tctctcggat gccaatcaat ttgtagacac ctttcacaat cgcattatgt ttcccctgac
    10201 aaatgaccaa ggaaaggtca ttgccttctc aggtcgtatc tggcaaaaaa cggattcaca
    10261 aacttctaag tataaaaaca gccgatcgac tgcaattttt aacaaaagtt acgaattata
    10321 tcatatggat agggcaaaaa aatcttctgg aaaaactagt gagatttacc tgatggaagg
    10381 attcatggat gttattgcag cctatcgggc tggaatcgaa aatgctgtgg cgtcgatggg
    10441 aacggccttg agtcgagagc atgttgagca tctgaaaagg ttaaccaaga aattggttct
    10501 tgtttacgat ggagataagg ctgggcaagc cgcgatattg aaagcattgg atgaaattgg
    10561 tgatatgcct gtgcaaatcg ttagcatgcc tgataacttg gatcctgatg agtatctaca
    10621 aaaaaatggt ccagaagact tggcctatct attaacaaaa actcgtatta gtccgattga
    10681 gttctacatt catcagtaca aacctgaaaa cagtgaaaat ctgcaggctc agattgagtt
    10741 tattgaaaaa atagctccct tgattgttca agaaaagtcc atcgctgctc aaaacagcta
    10801 tattcatatt ttagctgaca gtctggcgtc ctttgattat acccagattg agcagattgt
    10861 taatgagagt cgtcaggtgc aaaggcagaa tcgcatggaa agaatttcca gaccgacgcc
    10921 aatcaccatg cctgtcacca agcagttatc ggctattatg agggcagaag cccatctact
    10981 ctatcggatg atggaatccc ctcttgtttt gaacgattac cgtttgcgag aagactttgc
    11041 atttgctaca cctgaatttc aggtcttata tgacttgctt ggccagtatg gaaatcttcc
    11101 tccagaagtt ttagcagagc agacagagga agttgaaaga gcttggtacc aagttttagc
    11161 tcaggatttg cctgctgaga tatcgccgca ggaacttagt gaagtagaga tgactcgaaa
    11221 caaggctctc ttgaatcagg acaatatgag aatcaaaaag aaggtgcagg aagctagcca
    11281 tgtaggagat acagatacag ccttagaaga atttgaacgt ttaatttccc aaaagagaag
    11341 aatggagtaa taatggcaac aaaacaaaaa gaagtaacaa catttgacgt acaggtagca
    11401 gaatttatcc gtaatcataa gcaaaaaggg acagcaacag atgatgaaat caatgcaagt
    11461 ctggttattc cttttacctt ggacgctgat gggattgaag atctcttgca acggattcag
    11521 gatgcaggca tttctatcac agataacgaa ggaaatccaa gtgcgcgtgt tcttagcaat
    11581 gaagaagaac cagaactcag cgatgaggac ttgattgggt caacttctgc taaggtcaat
    11641 gaccctgtcc gtatgtactt gaaagaaata ggggtcgttc ctctcttgac caatgaagag
    11701 gagaaagagt tggcactggc tgttgaagct ggcgatatcg aagccaaaca acgtcttgcg
    11761 gaagccaatc ttcgtttggt tgtttccatt gccaaacgct atgtcggtcg tggcatgcag
    11821 ttccttgact tgattcaaga aggaaatatg ggcttgatga aggcggttga caagtttgac
    11881 tattctaaag ggttcaagtt ttcaacttat gcaacttggt ggattcgtca ggctatcact
    11941 cgtgctattg cagaccaagc tcgtaccatc cgtatcccag ttcacatggt tgaaactatc
    12001 aataaattgg ttcgtgaaca gcggaatctc cttcaagaat tggggcaaga tccgacacca
    12061 gaacagattg ctgaacgaat ggatatgaca cctgataagg ttcgtgaaat cttgaagatt
    12121 gcccaagaac cagtatctct tgaaactcct atcggtgaag aggacgatag ccaccttgga
    12181 gactttatcg aagatgaagt gattgaaaat ccagtggatt atacgactcg tatcgtcttg
    12241 cgtgagcaat tggatgaaat cttagatact cttacagacc gtgaagaaaa tgttctgcgt
    12301 ctacgttttg gactagatga tggaaaaatg cgcacacttg aagatgtggg gaaagtcttt
    12361 aacgtaactc gtgagcgtat ccgtcagatt gaagcaaagg ctttgagaaa actacgccaa
    12421 ccaagtcgta gcaaaccgct tcgtgatttt attgaagact aagagtgagg aaaatatggc
    12481 ttatacagaa gagcaaattg aaaacatcaa aacacggatt ttaacagcct tggaagaagt
    12541 catcgaccct gagttgggaa tcgatattgt caatcttggt ttgatctatg agattcgttt
    12601 tgacggtgac acagggcaaa cagagattga catgactttg acaactatgg gttgtccctt
    12661 agcagacctt ttgacagacc agatttatga tgctatgata gaggttccag aagtaacgga
    12721 tactgaggtt aaattagtct ggtatccagc ctggacagtt gaaaaaatga gtcgctatgc
    12781 ccgcattgcc ctaggcatta agtaaacata taaaagcatg tgagagactg ttggaaaagc
    12841 gaggaaattt cccctctttt cctctagtct ctcctttctt ttgctgattt tattcaaaga
    12901 aaatgatata atagtagtta tggagaaaaa gaaattacgc atcaatatgt tgagttcaag
    12961 tgagaaagta gcaggacagg gagtttcagg tgcttaccgt gaattagttc gtcttcttca
    13021 ccgtgctgcc aaggaccaat tgattgttac agaaaatctt ccaatcgagg cagatgtgac
    13081 tcactttcat acgattgatt ttccctatta tttatcaacc ttccaaaaga aacgctcagg
    13141 gagaaagatt ggctatgtgc atttcttgcc agctacactt gagggaagtt tgaaaattcc
    13201 atttttctta aagggaattg tgaaacgcta tgtattttct ttttacaacc ggatggagca
    13261 cttggttgtg gtcaatccta tgtttattga ggatttggta gcagctggta ttccacgtga
    13321 aaaagtgacc tatattccta actttgtcaa caaggaaaaa tggcatcctc taccacaaga
    13381 agaggtagtc aggctgcgca cagatcttgg tcttagtgac aatcagttta tcgtagtagg
    13441 tgctgggcaa gttcagaaac gtaaagggat tgatgacttt atccgtctgg ctgaggaatt
    13501 gcctcagatt acctttatct gggctggtgg cttctctttt ggtggtatga cagatggtta
    13561 tgaacactat aagaaaatta tggaaaatcc ccctaaaaat ttgatttttc caggcattgt
    13621 atcgccagag cggatgcgcg aattgtatgc tctagcggat cttttcttgt tgcctagtta
    13681 caatgagctc tttcctatga ctattttaga agctgcgagt tgtgaggctc ctattatgtt
    13741 gcgtgattta gatctctata aggtgatttt ggagggaaat tatcgggcga cagcgggtag
    13801 agaagagatg aaagaggcta ttttggaata tcaagcaaat cctgctgcct taaaagatct
    13861 caaagaaaag gctaagaata tttccagaga gtattctgaa gagcatctgt tacaaatctg
    13921 gttggacttt tatgagaaac aagccgcttt agggagaaag taaaaagtga ggtaatctat
    13981 gcgaattggt ttatttacag atacctattt tcctcaggtt tctggtgttg cgaccagtat
    14041 tcgaaccttg aaaacagaac ttgaaaagca gggacatgct gtttttatct ttacgacgac
    14101 agataaggat gtcaatcgct acgaagattg gcaaattatc cgcattccaa gtgttccttt
    14161 ctttgctttt aaggatcgtc gctttgccta ccgaggtttt agcaaggcac ttgaaattgc
    14221 taaacagtat cagctagata ttatccatac tcagacagaa ttttctcttg gcctgttggg
    14281 gatttggatt gcgcgtgaat tgaaaattcc agtcatccat acctatcaca cccagtatga
    14341 agactatgtc cattatattg ctaaggggat gttgatccgg ccgagtatgg tcaagtatct
    14401 ggttagaggt ttcctgcatg atgtggatgg ggttatttgc cctagtgaga ttgtccgtga
    14461 cttgctatct gattataagg tcaaggttga aaaacgggtc attcctactg ggattgaatt
    14521 agccaagttt gagcgtccgg aaatcaagca ggaaaatttg aaagaactgc gtagtaaact
    14581 agggattcaa gatggtgaaa agacgttgct tagtctttcg agaatctcct atgaaaaaaa
    14641 tattcaagca gttttagcag cctttgctga tgttctgaaa gaggaagaca aggttaaact
    14701 ggtagtagct ggggatggcc cttatctgaa tgacctcaaa gagcaagccc agaacctaga
    14761 gattcaagac tcagtcatct ttacagggat gattgctcct agtgagacgg ctctttacta
    14821 taaagcggcg gatttcttca tttcggcatc gacaagcgaa acgcaaggtt tgacctactt
    14881 ggaaagctta gccagtggaa cacctgtcat tgctcacgga aatccttatt tgaacaacct
    14941 catcagtgat aaaatgtttg gaaccttgta ctatggagaa catgatttgg ctggtgctat
    15001 tttggaagcc ctgattgcaa caccagacat gaacgagcat accttatcag agaaattgta
    15061 tgagatttca gctgagaact ttgggaaacg agtgcatgag ttttatctgg atgccattat
    15121 ttcaaataac ttccagaaag atttggctaa agatgatacg gtcagtcagc gtatctttaa
    15181 gacagttttg tatcttcagc aacaggtggt tgctgtacct gtaaaaggat ctagacgcat
    15241 gttgaaggct tcaaaaacac agttgatcag tatgagagac tattggaaag accatgaaga
    15301 atagaaagag gaacagctat gaaaaaaaca attaatgaga agcggtcgtg ataaaaagat
    15361 tgcgggtgtt tgtgctgggg tggcccatta tctggatatg gatccgacta tcgttcaagt
    15421 catttggggt gttcttactt gctgttacgg agctggaatt gtagcttaca ttattttatg
    15481 gattatcgca ccagtagcaa ctgactattg aaaactagct caattcatgc taagataata
    15541 gaaaatagaa tgtaacgaag gagagaaaaa tggcatttgg agataatgga aatcgtaaaa
    15601 aaactatgtt tgagaaaata accttgttta tcgtgattat catgctagta gcaagtttat
    15661 tgggaatttt tgcaactgca attggtgccc tcagtaatct ataaaataga ttcaagaaaa
    15721 tttagtgact gggatttccc agcccttttt taaagtgaga agaaataatg agtatgtttt
    15781 tagatacagc taagattaag gtcaaggctg gtaatggtgg cgatggtatg gttgcctttc
    15841 gtcgtgaaaa atatgtccct aatggaggcc cttggggtgg tgatggtggt cgtggaggca
    15901 atgtggtctt cgttgtagac gaaggactac gtaccttgat ggatttccgc tacaatcgtc
    15961 atttcaaggc tgattctggt gaaaaaggga tgaccaaagg gatgcatggt cgtggtgctg
    16021 aggaccttag agttcgagta ccacaaggta cgactgttcg tgatgcggag actggcaagg
    16081 ttttaacaga tttgattgaa catgggcaag aatttatcgt tgcccacggt ggtcgtggtg
    16141 gacgtggaaa tattcgtttc gcgacaccaa aaaatcctgc accggaaatc tctgaaaatg
    16201 gagaaccagg tcaggaacgt gagttacaat tggaactaaa aatcttggca gatgtcggtt
    16261 tagtaggatt cccatctgta gggaagtcaa cacttttaag tgttattacc tcagctaagc
    16321 ctaaaattgg tgcctaccac tttaccacta ttgtaccaaa tttaggtatg gttcgcaccc
    16381 aatcaggtga atcctttgca gtagccgact tgccaggttt gattgaaggg gctagtcaag
    16441 gtgttggttt gggaactcag ttcctccgtc acatcgagcg tacacgtgtt atccttcaca
    16501 tcattgatat gtcagctagc gagggccgtg atccatatga ggactaccta gctatcaata
    16561 aagagctgga gtcttacaat cttcgcctca tggagcgtcc acagattatt gtagctaata
    16621 agatggacat gcctgagagt caggaaaatc ttgaagactt taagaaaaaa ttggctgaaa
    16681 attatgatga atttgaagag ttaccagcta tcttcccaat ttctggattg accaagcaag
    16741 gtctggcaac acttttagat gctacagctg aattgttaga caagacacca gaatttttgc
    16801 tctacgacga gtccgatatg gaagaagaag cttactatgg atttgacgaa gaagaaaaag
    16861 cctttgaaat tagtcgtgat gacgatgcga catgggtact ttctggtgaa aaactcatga
    16921 aactctttaa tatgaccaac tttgatcgtg atgaatctgt catgaaattt gcccgtcagc
    16981 ttcgtggtat gggggttgat gaagcccttc gtgcgcgtgg agctaaagat ggggatttgg
    17041 tccgcattgg taaatttgag tttgaatttg tagactagga gactggtatg ggagataaac
    17101 cgatatcttt ccgagatgcg gatggtaatt ttgtttccgc cgcagacgtt tggaatgaaa
    17161 agaaattgga agaactattt aatcgtctca atccaaatcg tgccttgaga ttggcacgaa
    17221 ctaaaaagga aaatccatct cagtaaagaa gctaaaaaat cccgtgcctc atcagacacg
    17281 ggattttgtg gtacgacagg catgtatagc aaactgaatc tggaatagca cagcatatct
    17341 tctaaaatat agtaaaatga aatgagaaca ggacaaatcg atcaggacag taaaatcgat
    17401 ttctaacaat gttttagaag cagagatgta ctattctagt ttcaatcaac tatattgtta
    17461 taaattgatt tgaatttcaa aattaaattg tttgattctt atttcaattt gttatagtat
    17521 atctgatgtc aaagttctcg gcgagtcaaa tagcgattcc caagcctgac tatcgtgagg
    17581 tagcggatta aaatggtctg gggatagacc gttttaagtc tgacgctgga aataagaatt
    17641 gtcagaagaa gggatagcga aatcgtggct ctacgaacag gaacgtgata ataaggcgta
    17701 tatagcggat aagagggcat caaactctaa agtccaaaaa ggtagtcgta acctatatgc
    17761 gtaaatcacg agagtaattg aattcgtact aagattttct attttcactg taacctttta
    17821 acgcccttat atcttgtata cacgaggaaa gatgtacgac ttatcccgtg aggtctatca
    17881 ctataaagag aaaacgacag atagaagtga tcctgagtca cggttatctg tctgatagga
    17941 cggtatgtat aaaacgcttc tgtgaactga gagaaggggg agaagttctt gctaaaattt
    18001 agttgaacag ccgtattccg atacttagat aagagatcta gtcttagctc ctactcagtt
    18061 ttaggggata aaaaaggggc aatagcgatt cgagaaagat tatactcttc gaaaatctct
    18121 tcaaatcacg tcaatatcgc cttgtcgtat gtgtaggata ctgactacgt cagttccatc
    18181 tacaacctca aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gatctttgat
    18241 tttcattgag tattagtaat tcagttacta actcgtcaac tctgatttat ccaataaaat
    18301 tgaaaaggat ggaaaaaagg ataaatttat gatatacttt attttgaaga ccttattaga
    18361 aatcttgaaa gagtattgaa aacttagaat gagaaaaatt gttatcaatg gtggattacc
    18421 actgcaaggt gaaatcacta ttagtggtgc taaaaatagt gtcgttgcct taattccagc
    18481 tattatcttg gctgatgatg tggtgacttt ggattgcgtt ccagatattt cggatgtagc
    18541 cagtcttgtc gaaatcatgg aattgatggg agctactgtt aagcgttatg acgatgtatt
    18601 ggagattgac ccaagaggtg ttcaaaatat tccaatgcct tatggtaaaa ttaacagtct
    18661 tcgtgcatct tactattttt atgggagcct cttaggccgt tttggtgaag cgacagttgg
    18721 tctaccggga ggatgtgatc ttggtcctcg tccgattgac ttacacctta aggcgtttga
    18781 agctatgggt gccactgcta gctacgaggg agataacatg aagttatctg ctaaagatac
    18841 aggacttcat ggtgcaagta tttacatgga tacggttagt gtgggagcaa cgattaatac
    18901 gatgattgct gcggttaaag caaatggtcg tactattatt gaaaatgcag cccgtgaacc
    18961 tgagattatt gatgtagcta ctctcttgaa taatatgggt gcccatatcc gtggggcagg
    19021 aactaatatc atcattattg atggtgttga aagattacat gggacacgtc atcaggtgat
    19081 tccagaccgc attgaagctg gaacatatat atctttagct gctgcagttg gtaaaggaat
    19141 tcgtataaat aatgttcttt acgaacacct ggaagggttt attgctaagt tggaagaaat
    19201 gggagtgaga atgactgtat ctgaagacag catttttgtc gaggaacagt ctaatttgaa
    19261 agcaatcaat attaagacag ctccttaccc aggctttgca actgatttgc aacaaccgct
    19321 tacccctctt ttactaagag cgaatggtcg tggtacaatt gtcgatacga tttacgaaaa
    19381 acgtgtaaat catgtttttg aactagcaaa gatggatgcg gatatttcga caacaaatgg
    19441 tcatattttg tacacgggtg gacgtgattt acgtggggcc agtgttaaag cgaccgactt
    19501 aagagctggg gctgcactag tcattgctgg gcttatggct aaaggtaaaa ctgaaattac
    19561 caatatcgag tttatcttac gtggttattc tgatattatc gaaaaattac gtaatttagg
    19621 agcggatatt agacttgttg aggattaaac cgtagaggtg tttatgaata tttggaccaa
    19681 attagcaatg ttttcttttt ttgaaacgga tcgcttgtat ttgcgtcctt tcttttttag
    19741 tgatagtcag gacttccgcg agatagcttc aaatccagaa aatcttcaat ttattttccc
    19801 aacgcaggca agtctggaag aaagtcaata tgcactggcc aattacttta tgaagtcccc
    19861 tttgggagtg tgggcaattt gtgaccagaa aaatcaacaa atgattggtt ctattaaatt
    19921 tgagaagtta gatgaaatca aaaaagaagc tgagcttggc tattttttga gaaaagatgc
    19981 ttggtcgcaa ggatttatga cagaggttgt tagaaaaatt tgtcagcttt cttttgagga
    20041 atttggctta aaacaattat ttatcattac ccaccttgaa aataaagcta gccaaagagt
    20101 tgctcttaag tctggattta gtttgttccg tcagtttaag ggaagtgatc gttacacaag
    20161 aaaaatgcgg gattatcttg aatttcggta tgtaaaagga gagttcaatg agtaagcatc
    20221 aggaaattct aagctatttg gaggaattac cagtaggtaa aagggtcagt gttcgtagca
    20281 tttcgaatca tctaggagtt agtgatggaa cagcctatcg ggctattaaa gaagctgaaa
    20341 accgtggaat tgtggagacc cgtcctagaa gtggaacaat tcgtgttaaa tcccagaaag
    20401 ttgctataga gagattaacg tttgctgaaa ttgcagaagt gacttcttct gaggttctgg
    20461 ctgggcaaga aggtttagag agagaattta gtaagttttc aattggtgcc atgactgaac
    20521 aaaatatctt gtcttacctt catgatgggg ggctcttgat tgtcggagac cgaacccgta
    20581 ttcagttgct agccttggaa aatgaaaatg cagttctggt tacaggggga tttcaggttc
    20641 atgatgatgt gcttaaactg gccaatcaaa aagggattcc tgttctaaga agtaagcatg
    20701 atacctttac cgtcgcgacc atgatcaata aagccttgtc aaatgtccaa atcaagactg
    20761 atattctgac agttgagaaa ctttatcgcc ctagtcatga gtatggtttt ctgagagaga
    20821 cagatacagt taaagattat ttggacttgg ttcgtaagaa tcgtagcagc cgtttccctg
    20881 ttatcaatca acatcaggtc gttgttggtg ttgtaaccat gagagacgct ggtgataaat
    20941 caccaagcac gacaattgat aaggttatgt ctcgtagtct atttttggtt ggattatcga
    21001 caaatattgc caatgtgagt caacggatga tcgcagaaga ctttgaaatg gtaccagttg
    21061 ttcgaagcaa tcaaactttg cttggcgttg tgacgcgacg agatgtcatg gagaagatga
    21121 gccgttccca agtttcggct ctaccaactt tttctgagca gattggacaa aagctctctt
    21181 atcaccatga tgaagtagtc attacagtgg aaccctttat gctagaaaaa aatggagttt
    21241 tggctaatgg tgtattggca gaaattctga cccacatgac ccaagattta gttgttaata
    21301 gtggtcgcaa tctcattatc gagcagatgc tgatctactt tttgcaggct gttcagatag
    21361 atgatatatt gcgcattcag gcacggatta ttcatcatac gagacggtca gctataattg
    21421 attacgatat ttatcatggt caccagattg tttcaaaagc aaatgtgact gttaaaatta
    21481 attagaaact aggagaaaag atgataacat taaaatcagc tcgtgaaatc gaagctatgg
    21541 acaaggctgg tgattttcta gcaagtattc atataggctt acgtgatttg attaagccag
    21601 gcgtagatat gtgggaagtt gaagaatatg tccgccgtcg ttgtaaagaa gaaaatttcc
    21661 ttccacttca gattggggtt gacggtgcca tgatggacta tccttatgct acctgttgct
    21721 ctcttaacga tgaagtggct cacgctttcc ctcgtcatta tatcttgaaa gatggtgatt
    21781 tgctcaaagt tgatatggtt ttgggaggtc ccattgctaa atctgacctg aatgtctcaa
    21841 aattaaactt caacaatgtt gaacaaatga aaaaatacac tcagagctat tctggtggtt
    21901 tagcagactc atgttgggct tatgctgttg gtacaccgtc cgaagaagtc aaaaacttga
    21961 tggatgtaac caaagaagct atgtacaagg gtattgagca agctgttgtt ggaaatcgta
    22021 tcggtgatat cggtgcggct attcaagaat acgctgaaag tcgtggttac ggtgtagtgc
    22081 gtgatttggt tggtcatggt gttggcccaa ctatgcacga agaaccaatg gttcctaatt
    22141 atggtattgc aggtcgtgga ctccgtcttc gtgaaggaat ggtcttaacc attgaaccaa
    22201 tgatcaatac aggcgattgg gaaattgata cagatatgaa aactggttgg gcgcataaga
    22261 ccattgacgg tggattgtca tgtcagtatg aacaccaatt tgtcattacg aaagatggac
    22321 ctgttatctt gactagccaa ggtgaagaag gaacttatta ataaaaagtg aaaagactac
    22381 tggaagttta ttttgataaa aaatccagta gatcttttca taataaaacg cattgtatca
    22441 agtgttaggg gctgatatca tgcgtttttc tgcttttaag attttttcca actctgtttg
    22501 taagcgcatc ataacaaagg gtctaggatt cagggctctc ctcctatata ctattagtaa
    22561 agtaaaacta agggaggata ttttagtgtc gcagtctatt gttcctgtag agattccaca
    22621 atattgtcgt tttgattcta aaaagagaaa tggaattctg tttaatgttc gtattgccaa
    22681 tcttaaattt acttttttat attatacttc ctgcgaaaca aaatatggta tagtagttct
    22741 atgaatgatg aagcaagtaa acaactaact gatgcacgat ttaagcgtct tgttggtgtt
    22801 cagcgtacca cttttgaaga gatgttagct gtattaaaaa cagcttatca acttaaacac
    22861 gcaaaaggtg gacgaaaacc taaattaagc ctagaagacc ttcttatgcc cactcttcaa
    22921 tagtgcgaga atatcgaact tatgaagaaa ttgcggctga ttttggtatt cacgaaagca
    22981 actttatccg tcggagccaa tgggttgaaa taactcttgt tcaaagtggt tttacggttt
    23041 caagaactcc tctcagttct gaggacacgg taatgattga tgcgacggaa gtaaaaatca
    23101 atcgccctaa aaaaacaatt agcgaatgat tctggtaaaa agaaatttca cgctatgaag
    23161 gctcaagcga ttgtcacaag tcaagggaga attgtttctt tggatatcgc tgtgaactat
    23221 agtcatgata tgaagttgtt caaaatgagt cgtagaaata tcgaacaagc tggtaaaatc
    23281 ttggctgaca gtggttatca agggctcatg aagatatatc ctcaagcaca aactccacgt
    23341 aaatccagca aactcaagcc gctaacagct gaagataaag cctataacca tgcgctatct
    23401 aaggaaagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa aatattttca
    23461 acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgag tgctggtatt
    23521 atcaatcatg aactaggatt ctagttttgc aggaagtcta ttgaggtatt gagctagttt
    23581 atgaaaaaat tgggtgaaaa gtcgagtgtt ttagaaaccc acagtgtagt attctagttt
    23641 caatccacta tattttgcta ctccccgtaa agtttctatt ttccctgatt tctgatataa
    23701 tagaaatatt gacttcaaga gtaaggaaga gaagatgaac gcattattaa atggaatgaa
    23761 tgaccgtcag gctgaggcgg tgcaaacgac agaaggtccc ttgctaatca tggcaggggc
    23821 tggttctgga aagactcgtg ttttgaccca ccgtatcgct tatttgattg atgaaaagct
    23881 ggtcaatcct tggaatatct tggccattac ctttaccaac aaggctgcgc gtgagatgaa
    23941 agagcgtgct tatagcctca atccagcgac tcaggactgt ctgattgcga ccttccactc
    24001 catgtgtgtg cgtattttgc gtcgcgatgc ggaccatatt ggctacaatc gtaattttac
    24061 aattgtggat cctggtgaac agcgaacgct catgaaacgt attctcaaac agttgaactt
    24121 ggaccctaaa aaatggaatg aacgaactat tttggggacc atttccaatg ctaagaatga
    24181 tttgattgat gatgttgctt atgctgccca agctggcgat atgtatacgc aaattgtggc
    24241 ccagtgttat acagcctatc aaaaagaact tcgtcagtct gaatccgttg actttgatga
    24301 tttgattatg ctgaccttgc gtctctttga tcaaaatcct gatgttttga cctactacca
    24361 gcaaaaattc caatacatcc acgttgatga gtaccaagat accaaccacg ctcagtacca
    24421 attggtcaaa ctcttggctt cccgttttaa aaatatctgt gtggttgggg atgcggacca
    24481 gtctatctac ggttggcgtg gtgctgatat gcagaatatc ttggactttg aaaaggatta
    24541 ccccaaagcc aaggttgttt tgttggagga aaattaccgc tcaaccaaaa ccattctcca
    24601 agcggccaac gaggttatta aaaataataa aaatcgccgt cctaaaaatc tctggactca
    24661 aaacgctgat ggggagcaaa tcgtttacta tcgtgccgat gatgagctgg atgaggctgt
    24721 atttgtagcc agaaccatcg atgaacttag tcgcagtcaa aacttccttc ataaggattt
    24781 tgcagttctc tatcggacta atgcccagtc ccgtacaatt gaggaagccc tgctcaagtc
    24841 taacattcct tataccatgg ttggcggaac caaattctac agccgtaagg aaattcgcga
    24901 tattattgct tatctcaacc ttattgctaa tttgagtgac aatattagtt ttgagcgtat
    24961 tatcaacgag cctaaacgtg gaattggtct aggtacagtt gagaaaatcc gtgattttgc
    25021 aaatttgcaa aatatgtcta tgctggatgc ttctgctaat attatgttgt ctggtatcaa
    25081 gggtaaggca gcccaatcta tctgggattt tgccaatatg atgcttgatt tgcgggagca
    25141 gctagaccac ttaagcatta cagagttggt tgagtccgtc ctagaaaaaa caggttatgt
    25201 cgatattctt aacgcccaag cgactctaga aagcaaggca cgggttgaaa atatcgaaga
    25261 gtttctttct gttacgaaga actttgatga caccacggat gtgacagaag aggaaactgg
    25321 tctggacaaa ctgagtcgtt tcttaaatga cttggctttg attgccgaca cagattcagg
    25381 tagtcaggag acatcagaag tgaccttgat gaccctgcat gctgccaaag gtctcgaatt
    25441 tccagttgtc tttttgattg ggatggaaga aaatgtcttt ccacttagtc gtgcgactga
    25501 agattcagat gaattagaag aagagcgccg tctagcctat gtaggtatca cgcgtgcaga
    25561 gaaaattctc tatctgacca atgccaactc acgcttgctt tttggtcgta ccaattataa
    25621 ccgtccgact cgttttatta acgaaatcag ttcagacttg cttgagtatc aaggtctggc
    25681 tcgtcctgca aatacaagct ttaaggcatc atatagcagt ggtagtattt cctttggtca
    25741 aggtatgagt ttggctcagg ctcttcaaga ccgtaaacgc ggtgctgccc caaaatcaat
    25801 ccagtcaagc ggtcttccat ttggtcaatt tacagctggc gcaaaaccag catctagcga
    25861 ggcaaattgg tccattggtg atattgctct ccacaagaaa tggggagagg gaaccgttct
    25921 ggaagtttca ggtagcggtg ctaggcagga attgaaaatc aatttcccag aagtaggttt
    25981 gaaaaaactt ttagccagtg tggctccaat tgagaaaaaa atctaatttt ccatccttct
    26041 cacgaataat aaagtgagga ggatttttat gtacagtatt tcattccaag aagattcact
    26101 attaccaaga gaaaggctgg ccaaggaagg agttgaagcg cttagtaacc aagagttgct
    26161 agctatttta ctcaggacag gaacacgtca agctagcgtt tttgaaattg cccaaaaagt
    26221 cttgaacaat ctttcaagcc taacggattt gaaaaaaatg accctgcagg aattgcagag
    26281 tttgtctggt attgggcgtg ttaaggccat agaattacaa gctatgattg aactggggca
    26341 tcgtattcac aaacacgaga ctcttgaaat ggaaagtatt ctcagcagtc aaaagttggc
    26401 caagaagatg cagcaggaat taggggataa aaaacaagag cacctggtgg cactctatct
    26461 caatactcaa aatcaaatca tccatcagca gaccattttt atcgggtctg taactcgtag
    26521 tatcgctgaa ccgcgagaga ttcttcacta tgcaatcaag catatggcga cttctcttat
    26581 cttggtccac aatcatcctt caggagcggt agcgcctagc caaaatgatg atcatgtcac
    26641 taaacttgtt aaagaagcct gcgaattgat ggggattgtt ctcttggacc atttgattgt
    26701 ctctcattct aattacttta gttatcgtga aaagacagat ttaatctaaa gttcattaac
    26761 gacatagtca aagagttttt tatctttggg acgattttca aaaagaagtt ctggatgcca
    26821 ttggacaccg agaaaggcga catcatccgt actcatgaca gcctcaatga taccatcttt
    26881 aggatcatga gccacaactt ttaaatttgg tgctaagtcc ttgatgctct ggtggtggaa
    26941 ggagttgata tgagagattt ctccatagat ttcttggaga acggtatctg gttctgttac
    27001 caagcgttga gttgtgtact caacagaaga atcctgccaa tggtcttcga tatcttggta
    27061 caaagttcca cccatggcaa cgttaaagag ttgggtacca cggcagacag agaaaatggg
    27121 ctttttctgt ttaatagctt ccttgatgag ggccagttcg aagatatctc tttgaaggtg
    27181 atagtcatca ctatcaatgg ttttgggttc gccataaaat tttggatcga cattttgccc
    27241 acctgtcaag atgagcttgt caatcaaact gatatagtgg caggccattt cttgatcacc
    27301 aatcggtagg atgatgggaa tccctccagc atctttaacg ccttcaacaa agccttttgc
    27361 tgcgtagctc atcatgatgt catcatctgg atgagttttt tcgtttcctg taatcccaat
    27421 aactggtttt ttcataaaat gattttcgct ttctaatcct cttttcgcat gaagtagagg
    27481 agggtttgga gttcacttgt caaatcgaca tactgaacga ccacgtcttt tggtaaatgc
    27541 agatggactg gtgaaaaact gagaattcct ttcacaccag catcaaccaa gagattagca
    27601 acctcttgtg acttgacgct gggaacagtt aggatagcag tcttcacatc agcatccttg
    27661 attttatcct tgatctgaga aatcccgtaa atgggaatcc cgtcaggagt ttgggtaccg
    27721 acttcaggat ggtcgtctag gtcaaaggcc atgataatct tcatcttgtt acgttcgtgg
    27781 aagcggtagt ggagaagggc atggcccata tttccaatac caaccagcat gacattggta
    27841 atagagttgt cattgagcaa atcggcaaaa aatgtcatta gttttttgac atcatagcca
    27901 aaaccacgac gaccaagttc accaaaatag gaaaaatcac gacgtacggt cgctgaatca
    27961 ataccgatag cctctgcaat ttgcttagag ttggcacgtt caatcttttc tgcatgaaat
    28021 ctcttaaaaa ttcgatagta gagagagagt ctttttgctg tagcttttgg aatagcaaac
    28081 tgtttatctt tcacaaaatc acaacctttc tattcttcta ttttatagaa acattgtgaa
    28141 aaaatcaaca aaaataagaa aaaactaaga aaaatcttag ttttgatgta aaaaatctgc
    28201 atgagataga aaacggtaga ggtctccgac cagcccctga taaacttttt tgcccctaaa
    28261 agtcagagaa gtcacataaa gtgtatctgg taaggttaca catcctgaca aagtcaacat
    28321 gagagcctca tgatcctcat acttgagagt acgctctaca tgatagcagt ccttataggt
    28381 cagttcaaac attttggctc tatctttccg attttgtaaa gacaccacgt tctaccaagc
    28441 tatccatgag gaagtagaat ttttcctgat gaatatggtg gtcttctgat ttgaaaatat
    28501 caactagacg aaggccaaac ttgtcagtga tattgatttt agcccctgta agttccttgt
    28561 taatgatgat tttgagttgg aagccttcac cgctgtttgg cactttttcc aaaaggcgag
    28621 tcagttcata gttaccaacc ttagtttcaa aaaaggtgtt atctttgagg gtgaattttt
    28681 taacagaagg gctaagagtg taatcgtaac gacaattttt taactgaatg attttttcaa
    28741 atgccatatg gctaacctcc gataatttct tttaaggttt ttgcgagggt ttgtaggtct
    28801 tcaacggtat tttgtggcga caaactgatg cgaagggatt ccttcaagcg ttctgaattt
    28861 gcgccataca tggctttaag aacatggctg gattggacaa cgcctgcagt acaggctgag
    28921 ccagtagaga ttgaaattcc agctaaatct agccgaagga gtaagaggtc atttttctga
    28981 ccaggaaatc caatattgag aacataaggg agatgatgtt ttcctctatt caagtaatac
    29041 tgaatgccct ccagctctgc cagaaaggca gtttctagat tttgtacatg ttgaaaatgt
    29101 tcttcttgtt tttctaggtc ttcttttagg gctgcaacca tgcctacgat ggcaggcaga
    29161 ttttcagttc ctgcacgttt tttctgttcc tgatctccgc catgtagata ggaatcaaag
    29221 tccatgctag atgcgtagag aaaaccgatt cccttaggac catggaattt gtgggcagaa
    29281 gcagtgagaa aatcaatgcc caattcttct gaatgaattg ggattttacc aatagcctga
    29341 actgcatcaa catgataggc agcagggtgt tgcttgagta tttggccaat ttcagcgatg
    29401 ggaagtaggt ttcctgtctc attattggca aacatagtag aaaccaaaat cgtatcgtca
    29461 cgtaaagcct tttgaatttg ctgggctgtg atttcttgat tttctggctg gataatggtt
    29521 gcttcaaacc caaagtgttg aaccaagtaa tcaattgttt caaggacagc atggtgctcg
    29581 atggcagttg tgatgatatg ttttccttgt tcttggtgac gaagacagta gccaatgatg
    29641 gtagtattat tgccttcagt cccaccagaa gtgaaaaaga tatgttgagg ttttgtcctt
    29701 agtaactggg ctagttcctg acgggcttct cgcaagagtt tgccagcttg acgaccatga
    29761 ccatgaatac tagaaggatt tccgtgggtt tcttgcataa ccttggtcat agctgaaata
    29821 gcaactgctg acataggagt cgttgcagca ttgtccaaat aaatcaaaga atcaccttat
    29881 ttctttttat tgtaggcaaa gagtgggctg actggttttc tttcgtgaat acggacgata
    29941 gcatcaccaa ttaactcact agcagtgatg tagcatacat ttttaggagt tttttctttt
    30001 gttgctactg aatcagtcac aagaatttct ttaatattag tattgtcaag aagctcagca
    30061 gctccctcga cgaagagacc gtggctagaa acagcataaa tttctgtagc tccttcacgt
    30121 tcaacgattt tagaagcttc agagaaggta cgtcctgtat ttaaaatatc atcaatcaag
    30181 atagctttct taccttcaac atcaccaata atataacctt cgttacgagt tgcatcgtct
    30241 tgagggtagt cgataatggc gataggagca tcaagatatt cagccaggct acgcgcacgt
    30301 ttgacacctg aatttttagg gctaacgaca acaacatctg aaccaagcaa tcctttatcg
    30361 cagtaatgtt ttgcgaatag gggaacagtg aaaagattat ccactggaat atcaaagaaa
    30421 ccttgaacct gaacggcatg caaatcaaga gtcaggatac gatcaactcc agccttaacc
    30481 agcatattgg caactagttt tgctgtaagt ggctcacgag gacaagcaat gcggtcttga
    30541 cgtgcatagc caaaatatgg aaggacaacg ttgatactgt gggcacttgc acgcacacaa
    30601 gcatcgacca tgattaacaa ttccattagg tggttgttga cagggaaact tgttgattgg
    30661 atgatgtaaa catcataacc acggacactt tcttcgatat ttacttggat ttctccgtct
    30721 gaaaattgac gtgatgatag ttttccaagt gggacaccaa cagcttgggc aattttttgt
    30781 gcaatctctt ggttagagtt gagtgcgaaa agtttcatgt tttttctatc tgacattata
    30841 gaccgtcctc tgtaaacttt ataaatccta gttatattta ccttacatat atgaactggg
    30901 atttgtgtat ttttatcttt tctattttac caaaaaatgg agattatttc agctattttt
    30961 catacttttg acaaatcgaa ccaattttga aggagctttt tggtaggaaa tctgattttt
    31021 ctctaaaaat tgtcggaaat cctgtttgcc ttgctcatga ttttccactt caagctccaa
    31081 ttcgtaatct gtcatatcaa agtatcggct ctgatccagt gccatgagac caatagctgt
    31141 tttcatttca tagcgaagcg ttgttagaca accaagaacc tgccagttct tactttggat
    31201 accatgtttc gccaattcat ccagtactag cccttgagga agttcttcct tactcagata
    31261 gttctcagca tcttttagtt gcaatttttg gttgtattcc atgtttccaa cactctgcgg
    31321 gactttgagt gtcaactcag cccagtcttc aaaggttcga atgcgcatag cgactttctt
    31381 ttctcgcagt tcaaaatcag gcgtgtcgat gtagtaattt gtttgaagaa caggagtgac
    31441 acctgtgaac tggtctttta gacgattgta ttcatctttt ttcaatagtg ttttcaattc
    31501 aatttctaaa tgtttcattt ttcttacctt tttttatcgt tgaaagcgga tttatggtat
    31561 aataagcatt gtatttattg tatatgaatt tggagaaaaa atcaaagata tttttgacgg
    31621 ataatatgag aacaagggag aatatatgac cttagaatgg gaagaatttc tagatcctta
    31681 cattcaagct gttggtgagt taaagattaa acttcgtggt attcgtaagc aatatcgtaa
    31741 gcaaaataag cattctccaa ttgagtttgt gaccggtcga gtcaagccaa ttgagagcat
    31801 caaagaaaaa atggctcgtc gtggcattac ttatgcgacc ttggaacacg atttgcagga
    31861 tattgctggc ttacgtgtga tggttcagtt tgtagatgac gtcaaggaag tagtggatat
    31921 tttgcacaag cgtcaggata tgcgaatcat acaggagcga gattacatta ctcatagaaa
    31981 agcatcaggc tatcgttcct atcatgtggt agtagaatat acggttgata ccatcaatgg
    32041 agctaagact attttggcag aaattcaaat tcgtactttg gccatgaatt tctgggcaac
    32101 gatagaacat tctctcaact acaagtacca aggggatttc ccagatgaga ttaagaagcg
    32161 actggaaatt acagctagaa tcgcccatca gttggatgaa gaaatgggtg aaattcgtga
    32221 tgatatccaa gaagcccagg cactttttga tcctttgagt agaaaattaa atgacggtgt
    32281 aggaaacagt gacgatacag atgaagaata caggtaaacg aattgatctg atagccaata
    32341 gaaaaccgca gagtcaaagg gttttgtatg aattgcgaga tcgtttgaag agaaatcagt
    32401 ttatactcaa tgataccaat ccggatattg tcatttccat tggcggggat ggtatgctct
    32461 tgtcggcctt tcataagtac gaaaatcagc ttgacaaggt ccgctttatc ggtcttcata
    32521 ctggacattt gggcttctat acagattatc gtgattttga gttggacaag ctagtgacta
    32581 atttgcagct agatactggg gcaagggttt cttaccctgt tctgaatgtg aaggtctttc
    32641 ttgaaaatgg tgaagttaag attttcagag cactcaacga agccagcatc cgcaggtctg
    32701 atcgaaccat ggtggcagat attgtaataa atggtgttcc ctttgaacgt tttcgtggag
    32761 acgggctaac agtttcgaca ccgactggta gtactgccta taacaagtct cttggcggtg
    32821 ctgttttaca ccctaccatt gaagctttgc aattaacgga aattgccagc cttaataatc
    32881 gtgtttatcg aacactgggc tcttccatta ttgtgcctaa gaaggataag attgaactta
    32941 ttccaacaag aaacgattat catactattt cggttgacaa tagcgtttat tctttccgta
    33001 atattgagcg tattgagtat caaatcgacc atcataagat tcactttgtc gcgactccta
    33061 gccataccag tttctggaac cgtgttaagg atgcctttat cggtgaggtg gatgaatgag
    33121 gtttgaattt atcgcagatg aacatgtcaa ggttaagacc tttttaaaaa agcacgaggt
    33181 ttctaaggga ttgctggcca agattaagtt tcgaggtgga gctattctgg tcaataatca
    33241 accgcaaaat gcaacgtatc tattggacgt tggagactac gttaccattt acattcccgc
    33301 tgaggaaggc tttgaaacct tggaggctat tgagcatcca ttagatattc tctatgagga
    33361 tgaccacttt ctagtcttga ataaacccta tggagtggct tctattccta gtgtcaatca
    33421 ctctaatacc attgccaatt ttatcaaggg ttactatgtc aagcaaaatt atgaaaatca
    33481 gcaggttcac attgttacca gactagatag ggacacttct ggcttgatgc tctttgccaa
    33541 gcacggttat gcccatgcac gattagacaa gcagttgcag aagaaatcta tcgagaaacg
    33601 ctactttgct ttggttaagg gagatggaca tttggagcca gaaggggaaa ttattgctcc
    33661 gattgcgcgt gatgaagatt ccattattac cagacgagtg gctaaaggcg gaaagtatgc
    33721 ccatacttca tacaagattg tagcttctta tggaaatatt cacttggtct atattcacct
    33781 gcacactggt cgaacccatc aaatccgagt ccatttttct catatcggtt ttcctttgct
    33841 gggagatgat ttgtatggtg gtagtctgga agatggtatt caacgtcagg ctctgcattg
    33901 ccattaccta tccttttatc atccattttt agagcaagac ttgcagttag aaagtccctt
    33961 gccggatgat ttcagtaacc ttattaccca gttatcaact aatactctat aaaaactgtc
    34021 tcagagtata attattatct taaaggagaa aactcatgga agtttttgaa agtctcaaag
    34081 ccaaccttgt tggtaaaaat gctcgtatcg ttctccctga aggggaagag cctcgtattc
    34141 ttcaagcaac aaaacgctta gtaaaagaaa cagaagtgat tcctgttttg cttggaaatc
    34201 ctgaaaaaat taaaatttat cttgaaattg aaggaatcat ggatggttat gaggtcatcg
    34261 accctcaaca ttatcctcaa tttgaagaaa tggtttctgc cttggtggag cgtcgcaagg
    34321 gcaaaatgac tgaagaagat gtacgcaagg ttttggttga agatgtcaac tactttggtg
    34381 tgatgttggt ttacttgggc ttggttgatg gaatggtgtc aggagcgatt cactcaacag
    34441 cttcaacagt tcgtccagct ctacaaatca tcaaaactcg tccaaatgta actcgtactt
    34501 caggagcctt cctcatggtt cgtggtacgg aacgttacct atttggagac tgtgccatta
    34561 acatcaatcc agatgcagaa gccttggctg aaattgccat caactcagca atcacagcta
    34621 agatgtttgg catcgaacct aaaattgcca tgttgagcta ttctactaaa ggttcagggt
    34681 ttggtgaaag cgttgataag gtcgttgaag caactaaaat tgctcacgac ttgcgtcctg
    34741 accttgaaat cgatggtgag ttgcaatttg atgcagcctt tgttcctgaa actgcagctc
    34801 tgaaagctcc tggaagtacg gtagctggtc aagcaaatgt cttcatcttc ccaggtatcg
    34861 aggcaggaaa tatcggttac aagatggctg aacgcctggg tggctttgcg gctgtaggac
    34921 ctgttttgca aggtttaaac aagccagtta atgatctttc tcgtggatgt aatgcagatg
    34981 atgtttacaa gttgaccctc atcacagcag ctcaagcagt tcatcaatag tgaaaactat
    35041 aaagcgatat actatgctat actgtagtta tgaaactatg tacgaaaagc actgccatta
    35101 attcctgaga actaaattac tgattggtgt caaaaaggaa aacttccaag cgataatatc
    35161 ctgtctatac acgacctata gaaatctgta atatacatgt ccgtaaaacg ataaattccc
    35221 tttttgattt taaatgagta tgaaaagaga attttttggc tctttgtcaa ctgtagtggg
    35281 ttgaagtcag ctaagctcga gaaaggacaa attttgtcct ttcttttttg atattcagag
    35341 cgataaaaat ccgttttttg aagttttcaa agtttcgaaa accaaaggca ttgcgtttga
    35401 taagtttgat gagattattg gtcgcttcca atttggcgtt tgaatagggt agttgaaggg
    35461 cgttgacgat tttctctttg tcctttagaa aggttttaaa gacagtctga aaaagaggat
    35521 gaacctgctt tagattgtcc tcaataagcc cgaaaaattt ctctggttcc ttattctgga
    35581 agtgaaacag caagagttga tagagctgat agtgatgttt caagtcttgt gaatagctca
    35641 aaagcttgtc aagaatttct ttatttgtta agtgcatgcg aaaagtaggg cgataaaaac
    35701 gtttatcgct caatttacgg ctatcctgtt gaatgagttt ccagtagcgc ttgatagcct
    35761 tgtattcatg ggattttcga tgaaactgat tcatgatttg gacacgcaca cgactcatag
    35821 cacggctaag atgttgtaca atgtgaaagc gatcaagaac gattttagca ttcgggagtg
    35881 aaacagcctg ggagactgtt tcagcctgag cctagaaatt tgaaagcgaa gctgtttagc
    35941 caagtcatag taagagctaa acatatccat agtaatgatt ttgacgcgac atcggacggc
    36001 tctatcatat ttaagaaagt gatctcggat gacagcttgt gttctaccct caagaacagt
    36061 gatgatatcg agcttttcaa aatcttgcgc aatgaagctc atctccatct cccgattgaa
    36121 acagtcacta cccggactgt ttcaacgtcc caagacataa tctcaggaag acaagaaaaa
    36181 tcatgtttaa agtgaaaatc attgagctta cgaataacag ttgaagttga gatgaaaagc
    36241 tgatgggcaa tatcagtcat agaaatcttt tcaattaact tttgagcaat cttttggttg
    36301 atgatacgag ggatttggtg att
//
LOCUS       DAVLZS010000019        34776 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLZS010000019 DAVLZS010000000
VERSION     DAVLZS010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34776
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.019"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            49..6465
                     /locus_tag="VYO88_001002"
     CDS             49..6465
                     /locus_tag="VYO88_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1719119.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHEDIHSAMETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKEDSNQS
                     QGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIFN
                     GSAIETTPDNLDKIKQIEGISSIERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGK
                     NFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFN
                     YYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYK
                     MYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGI
                     PMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDK
                     VNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIA
                     VMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVF
                     SISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEI
                     DFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTY
                     GYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARP
                     MMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKE
                     IKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPE
                     IHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEA
                     LNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPG
                     TLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTSGSKIAN
                     IYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHFI
                     RGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQF
                     EPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYH
                     KVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQG
                     RNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISYY
                     LVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLFN
                     IHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGTD
                     LEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATKY
                     DFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKAEYP
                     YVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVT
                     TYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQSVLMS
                     ALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKFNVEAI
                     KEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNE
                     SVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQ
                     TGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDG
                     EIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSEL
                     KPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVI
                     NLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHS
                     QKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGL
                     KKKNQD"
     gene            7090..7566
                     /locus_tag="VYO88_001003"
     CDS             7090..7566
                     /locus_tag="VYO88_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1719120.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVCLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEALYAYIAEAIA"
     gene            7604..7909
                     /locus_tag="VYO88_001004"
     CDS             7604..7909
                     /locus_tag="VYO88_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1719121.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            7957..9432
                     /locus_tag="VYO88_001005"
     CDS             7957..9432
                     /locus_tag="VYO88_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1719122.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            9458..9535
                     /locus_tag="VYO88_001006"
                     /pseudo
     CDS             9458..9535
                     /locus_tag="VYO88_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            9737..16438
                     /locus_tag="VYO88_001007"
     CDS             9737..16438
                     /locus_tag="VYO88_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1719123.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLQKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPVAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEAHVKVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDVIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     VPKSYVIEYYVGKTVPTAPKNPNFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(16695..17543)
                     /locus_tag="VYO88_001008"
                     /pseudo
     CDS             complement(16695..17543)
                     /locus_tag="VYO88_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17755..18114)
                     /locus_tag="VYO88_001009"
     CDS             complement(17755..18114)
                     /locus_tag="VYO88_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1719124.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            18206..19162
                     /locus_tag="VYO88_001010"
                     /pseudo
     CDS             18206..19162
                     /locus_tag="VYO88_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            19146..19703
                     /locus_tag="VYO88_001011"
     CDS             19146..19703
                     /locus_tag="VYO88_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1719125.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            19696..19950
                     /locus_tag="VYO88_001012"
     CDS             19696..19950
                     /locus_tag="VYO88_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719126.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            19962..22016
                     /locus_tag="VYO88_001013"
     CDS             19962..22016
                     /locus_tag="VYO88_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1719127.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            22195..23055
                     /locus_tag="VYO88_001014"
     CDS             22195..23055
                     /locus_tag="VYO88_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1719128.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            23266..23976
                     /gene="ccdA2"
                     /locus_tag="VYO88_001015"
     CDS             23266..23976
                     /gene="ccdA2"
                     /locus_tag="VYO88_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1719129.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            23996..24562
                     /locus_tag="VYO88_001016"
     CDS             23996..24562
                     /locus_tag="VYO88_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1719130.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            24573..25685
                     /gene="msrB"
                     /locus_tag="VYO88_001017"
     CDS             24573..25685
                     /gene="msrB"
                     /locus_tag="VYO88_001017"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1719131.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            25998..26735
                     /locus_tag="VYO88_001018"
     CDS             25998..26735
                     /locus_tag="VYO88_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719132.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            26732..28423
                     /locus_tag="VYO88_001019"
     CDS             26732..28423
                     /locus_tag="VYO88_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1719133.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLTYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFEANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            28539..29102
                     /locus_tag="VYO88_001020"
     CDS             28539..29102
                     /locus_tag="VYO88_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1719134.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            29124..34769
                     /gene="zmpB"
                     /locus_tag="VYO88_001021"
     CDS             29124..34769
                     /gene="zmpB"
                     /locus_tag="VYO88_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpB"
                     /protein_id="HEV1719135.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEQAPVEPEKQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTTEVVPDDTKYVDEEV
                     VERQGSKGVQVTKTTYETVEVVETDKVLSTTTEVKTPVVPKVVKKGTKPVEGTAVETR
                     EEVIPFATKEQEDDTLKRGTRQVAQEGVNGKKQITETYKTIRGEKTNEAPTVEETVLQ
                     APQDEIIKKGTKGLEKPTLEWVKTDKDVLKKSATASYTLNKPDGVEIKSIKVALKDNT
                     GTVIKEVTVEENNLNATLDNLKYYQGYTLSTTMVYNRGEGEETEMLEDKEVQLDLKKV
                     EIKSIKETSLMSVDDAGVETDKSLLTEKPTDVAPLYLRVTTHDNKTTRLAVSSVEEVV
                     VDGKTLYKVVAKAPDLVQRREDDTLSEEYVHYFEKQLPKVDNVYYNFNELVKDMQANP
                     TGEFKLGADLNAVNVKPAGKAYVMAKFRGTLSSVENHQYTIHNLERPLFNEAEGATLK
                     NFNLGNVNINMPWADKVAPIGNMFKKSTLENIKVVGSVTGNNDVTGAVNKLDEANMRN
                     VAFIGKINSLGDKGWWSGGLVSESWRSNTDSVYFDGDIVGNNSKFGGLVAKVNHGSNQ
                     WDVKQKGRLTNSVVKGTMTLKNHGQSGGLVHENYDWGWVENNISMMKVNNGEIMYGSG
                     SIDGDPYFGFDYFKNNYYVKDVATGESTYKRSKQIQSISQAEADAKIANMGITANTFA
                     IQDPVVNKLNRIIDRDSEYKAIQDYQETRNLAYRNLEKLQPFYNKEWIVNQGNKLTDE
                     SNLVKKTVLSVTGMKSGQFVTDLSSVDKIMIHYADGTKEEFGVSAISDSRVKQVKEYN
                     VDDLGVVYTPNMVDKNRDSLITKVKEKLSSVALDSAEVKSITNNPASLYLEESFAEVR
                     ETLDKLVKSLLENEDHQLNSDEVAEKALLKKVEDNKAKIILALTYLNRYYGIDYDGLN
                     FKHLMMFKPDFYGKTPSILDFLIRIGSAEKNLKGDRSLEAYREVIGGTIGKGELNGLL
                     GYNMRLFTKYTDLNDWFIHAAKNVYVSEPETTTEDFKDKRHRIYDGLNNDVHGRMILP
                     LLNLKKAHIFVISTYNTIAFSSFEKYGKNTEEERNAYKAEIDRVAKAQQRYLDFWSRL
                     ALPKVRNQLLKSQNSVPTPVWDNQVYVGLGGANRMGYGDGGRVVTPVRELFGPTDRWH
                     QINWNMGAMAKIYERPWKDDQVYFMVTNMMEPFGISAFTHETTHVNDRMAYYGGDWHR
                     EGTDLEAFAQGMLQTPDKSTTNGEYGALGINMAYERKNDGEQLYNYDPEKLDSREKID
                     SYMKNYNESMMMLDYLEASAVIRQNLSDNSKWFKKMDKEWRTNADRNRLIGEPHQWDK
                     LRDLTEEEKKLPIDSIDKLVENNFVTLHGMPKNGRYRTEGFDSSYQPVNMMAGVFGGN
                     TSKSTVGSISFKHNAFRMWGYYGYENGFIPYVSNKLKGAANKENKGLLGDDFIIKKVS
                     KNQFQNLEEWKKHWYHEVYDKAQKGFVEIEVDGVKISTYAQLQSLFEEAVSKDLAGMD
                     DKNIKNHYQYTENLKWKIYKQLLKNTDGFSSDLFTAPQA"
BASE COUNT        11401 a         6053 c         7516 g         9806 t
ORIGIN      
        1 taaagtttat tatctattgg aagttatata aatatgtaag gaattaaaat gaaaaaaagt
       61 acagtattgt cattaaccac agctgcagtt attttagcag cctatgcccc taatgaggta
      121 gtcttagcag acacatctag ctctgaagat gctttaagca tctctgataa agaaaaagta
      181 gcagaaaata aagagaaaca tgaagatatc catagtgcta tggaaacttc aaaggatact
      241 gaagaaaaga aaacaacagt tattgaggaa aaagaagttg ttagtaaaaa tcctgtgata
      301 gacactaaaa ctagcaatga agaagcaaga atcaaagaag attccaatca atcccaagga
      361 gataatgcac actcgtctgc aaataaaggc acagaaaatc ccaaaaaaga agatagactt
      421 gtctatattg ctgaatttaa agataaagaa tctggagaaa aagcaatcaa ggaactatcc
      481 agtcttaaga atacaaaagt tttatatact tatgatagaa tttttaacgg tagtgccata
      541 gaaacaactc cagataactt ggacaaaatt aaacaaatag aaggtatttc atcgattgaa
      601 agggcacaaa aagtccaacc catgatgaat catgccagaa aggaaattgg agttgaggaa
      661 gctattgatt acctaaagtc tatcaatgct ccgtttggga aaaattttga tggtagaggt
      721 atggtcattt caaatatcga tactggaaca gattatagac ataaggctat gagaatcgat
      781 gatgatgcca aagcctcaat gagatttaaa aaagaagact taaaaggcac tgataaaaat
      841 tattggttga gtgataaaat ccctcatgcg ttcaattatt ataatggtgg caaaatcact
      901 gtagaaaaat atgatgatgg aagggattat tttgacccac atgggatgca tattgcaggg
      961 attcttgctg gaaatgatac tgaacaagac atcaaaaact ttaacggcat agatggaatt
     1021 gcacctaatg cacaaatttt ctcttacaaa atgtattctg acgcaggatc tgggtttgcg
     1081 ggtgatgaaa caatgtttca tgctattgaa gattctatca aacacaacgt tgatgttgtt
     1141 tcggtatcat ctggttttac aggaacaggt cttgtaggtg agaaatattg gcaagctatt
     1201 cgggcattaa gaaaagcagg cattccaatg gttgtcgcta cgggtaacta tgcgacttct
     1261 gcttcaagtt cttcatggga tttagtagca aataatcatc tgaaaatgac cgacactgga
     1321 aatgtaacac gaactgcagc acatgaagat gcgatagcgg tcgcttctgc taaaaatcaa
     1381 acagttgagt ttgataaagt taacataggt ggagaaagtt ttaaatacag aaatataggg
     1441 gcctttttcg ataagaataa aatcacaaca aatgaagatg gaacaaaagc tcctagtaaa
     1501 ttaaaatttg tatatatagg caagggacaa gaccaagatt tgataggttt ggatcttagg
     1561 ggcaaaattg cagtaatgga tagaatttat acaaaggatt taaaaaatgc ttttaaaaaa
     1621 gctatggata agggtgcacg cgccattatg gttgtaaata ctgtaaatta ctacaataga
     1681 gataattgga cagagcttcc agctatggga tatgaagcgg atgaaggtac taaaagtcaa
     1741 gtgttttcaa tttcaggaga tgatggtgta aagctatgga acatgattaa tcctaataaa
     1801 aaaactgaag tcaaaagaaa taataaagaa gattttaaag ataaattgga gcaatactat
     1861 ccaattgata tggaaagttt taattccaac aaaccgaatg taggtgacga aaaagagatt
     1921 gactttaagt ttgcacctga cacagacaaa gaactctata aagaagatat catcgttcca
     1981 gcaggatcta catcttgggg gccaagaata gatttacttt taaaacccga tgtttcagca
     2041 cctggtaaaa atattaaatc cacgcttaat gttattaatg gcaaatcaac ttatggctat
     2101 atgtcaggaa ctagtatggc gactccaatc gtggcagctt ctactgtttt gattagaccg
     2161 aaattaaagg aaatgcttga aagacctgta ttgaaaaatc ttaagggaga tgacaaaata
     2221 gaccttacaa gtcttacaaa aattgcccta caaaatactg cgcgacctat gatggatgca
     2281 acttcttgga aagaaaaaag tcaatacttt gcatcaccta gacaacaggg agcaggccta
     2341 attaatgtgg ccaatgcttt gagaaatgaa gttgtagcaa ctttcaaaaa cactgattct
     2401 aaaggtttgg taaactcata tggttccatt tctcttaaag aaataaaagg tgataaaaaa
     2461 tactttacaa tcaagcttca caatacatca aacagacctt tgacttttaa agtttcagca
     2521 tcagcgataa ctacagattc tttaactgac agattaaaac ttgatgaaac atataaagat
     2581 gaaaaatctc cagatggtaa gcaaattgtt ccagaaattc acccagaaaa agtcaaagga
     2641 gcaaatatca catttgagca tgatactttc actataggcg caaattctag ctttgatttg
     2701 aatgcggtta taaatgttgg agaggccaaa aacaaaaata aatttgtaga atcatttatt
     2761 cattttgagt cagtggaaga aatggaagct ctaaactcca acgggaagaa aataaacttc
     2821 caaccttctt tgtcgatgcc tctaatggga tttgctggga attggaacca cgaaccaatc
     2881 cttgataaat gggcttggga agaagggtca agatcaaaaa cactgggagg ttatgatgat
     2941 gatggtaaac cgaaaattcc aggaacctta aataagggaa ttggtggaga acatggtata
     3001 gataaattta atccagcagg agttatacaa aatagaaaag ataaaaatag aacatctcta
     3061 gatcaagatc cagacttatt tgcctttaac aaccaaggtg ttcatgcaga atccactagt
     3121 ggttctaaga ttgctaacat ttatccttta gattcaaatg gaaatcctca agatgctcaa
     3181 ctagaaagag gactaactcc atctccactt gttctaagaa gtgcagaaga aggactaatt
     3241 tcaattgtaa acaccaacaa agaaggagaa aaccaaaaag accttaaagt tgtatcaaga
     3301 gagcacttca taagaggaat tctaaattct aagggaaatg acgctaaggg tatcaaatca
     3361 tccaaactaa aagtttgggg tgacttgaaa tgggatggac tcatctataa cccaagaggt
     3421 agagaagaaa atgccccaga aagtaaggat aaccaagatc cagctactaa gatacgagga
     3481 caatttgaac cgattgcgga aggtcaatat ttctataaat ttaaatatag attaactaaa
     3541 gattacccat ggcaggtttc ctatattcct gtaaaaattg ataacacagc ccctaagatt
     3601 gtttcggttg atttttcaaa tcctgaaaaa attaagctaa tcacaaagga tacttatcac
     3661 aaggtaaaag atcaatacaa gaatgaaact ttatttgcta gagatcaaaa agaacatcct
     3721 gaaaaatttg atgagattgc aaatgaggtg tggtatgcag gagctgctct tgttaatgaa
     3781 gatggagagg ttgagaaaaa tcttgaagta acttatgcag gtgagggtca aggaagaaat
     3841 aggaagcttg ataaagatgg gaatactatc tatgaaatta gcggagcagg agatctaaga
     3901 ggaaaaatca tcgaagtaat cgccctagat ggagcaagca actttaccaa aatccatagg
     3961 attaaatttg ctaatcaagc tgatgaaaaa gggatgattt cctattatct agtagatcct
     4021 gatcaggatt catctaaata ccaaaagctt ggcgaaattc ctgaatctaa atttaagaat
     4081 ttaaaaaatg ttaaagatga tagcctaaac aaagagacag ctgaggtgga aaataacctt
     4141 ttagtagata atcagtctat cgaaggaaaa tctctcttta atattcataa aactatttca
     4201 acaattagag actttgaaaa taaagaccta aagaaactca ttaaaaagaa atataagcaa
     4261 gaagacgact ttgtaaatgg tggaacaaga acagtagagc gtgattataa atacgatgat
     4321 aaaggaaata taatagccta cgatgatggg actgatctag aatatgaaac tgagaaactt
     4381 gacgaaatca aatcaaaaat ttatggtgtt ctaagtccgt ctaaagatgg acactttgaa
     4441 attcttggaa agataagtaa tgtttctaaa aatgccaagg tatattatgg gaataactat
     4501 aaatctatag aaatcaaagc gaccaagtat gatttccact caaaaacgat gacatttgat
     4561 ctatacgcta atattaatga tattgtggat ggattagctt ttgcaggaga tatgagatta
     4621 tttgttaaag ataatgatca gaaaaaagct gaaattaaaa ttagaatgcc tgaaaaaatt
     4681 aaggaaacta aagcagaata tccctatgta tcaagttatg ggaatgtcat agaattaggg
     4741 gaaggagatc tttcaaaaaa caaaccagac aatttaacta aaatggaatc tggtaaaatc
     4801 tattctgatt cagaaaaaca acaatatctg ttaaaggata atatcattct aagaaaaggc
     4861 tatgcactaa aagtgactac ctataatcct ggaaaaacgg atatgttaga aggaaatgga
     4921 gtctatagca aggaagatat agcaaaaata caaaaggcca atcctaatct aagagccctt
     4981 tcagaaacaa caatttatgc tgatagtaga aatgttgaag atggaagaag tacccaatct
     5041 gtattaatgt cggctttgga cggctttaac attataaggt atcaagtgtt tacatttaaa
     5101 atgaacgata aaggggaagc tatcgataaa gacggaaatc ttgtgacaga ttcttctaaa
     5161 cttgtattat ttggtaagga tgataaagaa tacactggag aggataagtt caatgtagaa
     5221 gctataaaag aagatggctc catgttattt attgatacca aaccagtaaa cctttcaatg
     5281 gataagaact actttaatcc atctaaatct aataaaattt atgtacgaaa tccagaattt
     5341 tatttaagag gtaagatttc tgataagggt ggttttaact gggaattgag agttaatgaa
     5401 tcggttgtag ataattattt aatctacgga gatttacaca ttgataacac tagagatttt
     5461 aatattaagc tgaatgttaa agacggtgac atcatggact ggggaatgaa agactataaa
     5521 gcaaacggat ttccagataa ggtaacagat atggatggaa atgtttatct tcaaactggc
     5581 tatagcgatt tgaatgctaa agcagttgga gtccactatc agtttttata tgataatgtt
     5641 aaacccgaag taaacattga tcctaaggga aatactagta tcgaatatgc tgatggaaaa
     5701 tctgtagtct ttaacatcaa tgataaaaga aataatggat tcgatggtga gattcaagaa
     5761 caacatattt atgtaaatgg aaaagaatat acatcatttg atgatattaa acaaataaca
     5821 gacaagacac taaacattaa gattgttgta aaagattttg caagaaatac aaccgtaaaa
     5881 gaattcattt taaataaaga tacgggagag gtaagtgaat taaaacctca tagggtaact
     5941 gtgaccattc aaaatggaaa agaaatgagt tcaacgatag tgtcggaaga agattttatt
     6001 ttacctgttt ataagggtga attagaaaaa ggataccaat ttgatggttg ggaaatttct
     6061 ggtttcgaag gtaaaaaaga cgctggctat gttattaatc tatcaaaaga tacctttata
     6121 aaacctgtat tcaagaaaat agaggagaaa aaggaggaag aaaataaacc tacttttgat
     6181 gtatcgaaaa agaaagataa cccacaagta aaccatagtc aattaaatga aagtcacaga
     6241 aaagaggatt tacaaagaga agatcattca caaaaatctg attcaactaa ggatgttaca
     6301 gctacagttc ttgataaaaa caatatcagt agtaaatcaa ctactaacaa tcctaataag
     6361 ttgccaaaaa ctggaacagc aagcggagcc cagacactat tagctgccgg aataatgttt
     6421 atagtaggaa tttttcttgg attgaagaaa aaaaatcaag attaagacaa aagctataga
     6481 aaaaatggtt tatgtactga gattagatag tgaggtgatg acatagtttt gtgaaaacag
     6541 ccatttataa ctcaattatt tagtttactt cactattgat actatttgga gttattaatg
     6601 gacttagttt agataactaa tgaattgatt gaaagggtta gtattgacaa tattggtcat
     6661 attgattaga aaatagagtc tatcaaaatt taaaggctaa tagaggtgat gagacaattt
     6721 caaggaatta agtagcgttt ggttgcttaa ttccttttta tttggaagga agtttttcgt
     6781 aaccgcccaa taacgaagtc tattggacgg ttacgatatg atcactgact tcgtcagtct
     6841 tatctacaac ctcaaaactg tgttttgagc aacctgcggc tagcttccta gtttactctt
     6901 tgattttcat tgagtattag aacagaaaaa atgcttggag tatttgtttg tgtgtttatt
     6961 tttatataac aaactataaa caaaacaaaa atataaaaaa agagacaaaa aagaacagaa
     7021 agtaattgac aacggtttca tatagtgtta tacttatggc ataaagttaa tggaaagaag
     7081 ggaaaactta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg cttagaagcg
     7141 gataatcaag aacaactctt tgatcaggtt gcaactttat tggaagaacg agaaattgtc
     7201 actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac tggtttagat
     7261 atggaatttc taggaaagga cttgccaaat gtagcgattc ctcatacaga tattgttcat
     7321 aatctagctg agaaagtggt ggttgttcga ttagagaaac cagtaacttt tcacaatatg
     7381 atagctcctg ataaggaagt agaagtatgc ttactcttct ttatcatcaa taattcaagt
     7441 tcaagtcaaa cgaacattct tgctcagttg atggacttct tcacaggaaa tggtcatctt
     7501 gaagacctat caaaaatttc tgaaccagaa gccctttatg cttatatagc tgaagcaatc
     7561 gcttaatctt gtctattaaa aaataaaatc ggaggaaatc caaatgatta aaattcttgc
     7621 tgcctgcggt gcaggtgtta actcaagtca ccaaattaaa agtgctctag aagaagaact
     7681 ttcaaaccgt ggttatgatg ttcactgtga tgcagtcatg gtgaaagatg taaacgaaga
     7741 ccttatgaaa ggttacgata tctttacacc aatcgctgca acagatcttg gttttgaacc
     7801 aggtatccca gttatcgaag ctgggccaat cttattccgt ataccagcaa tgagcgctcc
     7861 agtatttgac aatattgaag cagctattaa agaacacgga ttaagctaat tctaatttgt
     7921 taacattcat ataacataaa aaagggagga actgttatgg atgcaatctt tgacctaatc
     7981 ggaaaggttt tcaatcccat cttagaaatg ggtggacctg tcatcatgtt aatcattttg
     8041 acagtattgg ctttactttt tggagtgaaa ttctccaaag cgcttgaagg tggtatcaaa
     8101 cttgccatcg ctcttacagg tatcggtgct atcatcggta tgctaaatgg tgctttctca
     8161 gcatcacttg caaaattcgt tgaaaacact ggtatacaat tgagtattac cgacgttggt
     8221 tgggcaccac ttgcaacaat cacttggggt tctgcttgga cactttactt cttgctcatc
     8281 atgttgattg tcaacgtagt gatgcttgct atgaagaaaa ccgatacact tgatgtcgat
     8341 atctttgata tctggcactt gtctatcaca ggtctcttga ttaaatggta tgctgataac
     8401 aatggtgtga gtcaaggggt ttcactcttg attgctacag cagctatcgt tcttgtcggt
     8461 gtgttgaaaa ttatcaactc tgacttgatg aaacctacat ttgatgacct tcttaacgcc
     8521 ccaagttcat caccaatgac atcaactcac atgaactaca tgatgaaccc agttatcatg
     8581 gttttggata agatttttga aaaattcttc ccaggccttg ataaatatga ctttgatgct
     8641 gctaaattga acaagaaaat cggtttctgg ggatctaaat tcttcatcgg tttcatcctt
     8701 ggtatcgtta tcggtattat gggaactcca catccaattg caggtgttgc agatgcagat
     8761 aaatggcgtc ttgttatcaa aggatggttg tctcttggtt tgactgccgg tgtatctttg
     8821 gaactcttct cacttatcgg ttcatggttc atcgcagccg tagaaccact atcacaaggt
     8881 attacaaacg ttgctactaa acgtcttcaa ggacgtaaat tcaatatcgg tcttgactgg
     8941 ccattcatcg ctggtcgtgc tgaaatctgg gcttgtgcca acgtacttgc accaatcatg
     9001 ttgattgaag cagtgcttct ttcaaaagtt ggaaatggta tcttgccact tgcaggtatc
     9061 atcgctatgg gtgttactcc agctctcttg gttgtaactc gtggtaaatt gctccgtatg
     9121 attatcttcg gaacactctt gttgccactc ttccttcttt caggtaccct tattgcacca
     9181 tttgcaacag aacttgctaa aggtgtaggt gccttcccag aaggtgtgag ccaaactcaa
     9241 ttgattactc actctactct tgaaggacca atcgaaaaac ttcttggttg gacaattggt
     9301 aacactacaa ctggtgatat caaagcaatc cttggtgcag tagccttcct tgtattctat
     9361 atcggtatct ttgcttggta cagaaaacaa atgatcaaac gtaacgaaga gtacgcagca
     9421 aaagcaaaat aatgcgctcc tataaaatat aaactcaatg aaaatcaaag agcaaactag
     9481 gaagctagcc gcaggttgct caaaacacag ttttgaggtt gtagataaga ctgacgaagt
     9541 cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta atcatatcta
     9601 cggcaaggcg acactgacga agtttgaatt ggattttcgc agagtgtaaa ttgttgaaac
     9661 taggttgtca taccatgtat accacttggg ctttggtagt agctaactgc actaaatata
     9721 atataaggag ggttttatgg ggaaaggcca ttggaatcgg aaaagagttt atagcattcg
     9781 taagtttgct gtgggagctt gctcagtaat gattgggact tgtgcagttc tattaggagg
     9841 aaatatagct ggagaatctg tagtttatgc ggatgaaaca cttattactc atactgctga
     9901 gaaacctaaa gaggaaaaaa tgatagtaga agaaaaggct gataaagctt tggaaactaa
     9961 aaatgtagtt gaaaggacag aacaaagtga acctagttca actgaggcta ttgcatctga
    10021 gaagaaagaa gatgaagccg taactccaaa agaggaaaaa gtgtctgcta aaccggaaga
    10081 aaaagctcca aggatagaat cacaagcttc aagtcaagaa aaaccgctca aggaagatgc
    10141 taaagctgta acaaatgaag aagtgaatca aatgattgaa gacaggaaag tggattttaa
    10201 tcaaaattgg tactttaaac tcaatgcaaa ttctaaggaa gccattaaac ctgatgcaga
    10261 cgtatctacg tggaaaaaat tagatttacc gtatgactgg agtatcttta acgatttcga
    10321 tcatgaatct cctgcacaaa atgaaggtgg acagctcaac ggtggggaag cttggtatcg
    10381 caagactttc aaactagatg aaaaagacct caagaaaaat gttcgcctta cttttgatgg
    10441 cgtctacatg gattctcaag tttatgtcaa tggtcagtta gtggggcatt atccaaatgg
    10501 ttataaccag ttctcatatg atatcaccaa ataccttcaa aaagatggtc gtgagaatgt
    10561 gattgctgtc catgcagtca acaaacagcc aagtagccgt tggtattcag gaagtggtat
    10621 ctatcgtgat gtgactttac aagtgacaga taaggtgcat gttgagaaaa atgggacaac
    10681 tattttaaca ccaaaacttg aagaacaaca acatggcaag gttgaaactc atgtgaccag
    10741 caaaatcgtc aatacggacg acaaagacca tgaacttgta gccgaatatc aaatcgttga
    10801 acgaggtggt catgctgtaa caggcttagt tcgtacagcg agtcgtacct taaaagcaca
    10861 tgaatcaaca agcctagatg cgattttaga agttgaaaga ccaaaactct ggaccgtttt
    10921 aaatgacaaa cctgccttgt acgaattgat tacgcgtgtt taccgtgacg gtcaattggt
    10981 tgatgctaag aaggatttgt ttggttaccg ttactatcac tggactccaa atgaaggttt
    11041 ctctttgaat ggtgaacgta ttaaattcca tggagtatcc ttgcaccacg accatggggc
    11101 gcttggagca gaagaaaact ataaagcaga atatcgccgt ctcaaacaaa tgaaggagat
    11161 gggagttaac tccatccgta caacccacaa ccctgctagt gagcaaacct tgcaaatcgc
    11221 agcagaacta ggtttactcg ttcaggaaga ggcttttgat acttggtatg gtggcaagaa
    11281 accttatgac tatggacgtt tttttgaaaa agatgccact cacccagaag ctcgaaaagg
    11341 tgaaaaatgg tctgattttg acctacgtac catggtcgaa agaggcaaaa acaaccctgc
    11401 tatcttcatg tggtcaattg gtaatgaaat aggtgaagct aatggtgatg cccactcttt
    11461 agcaactgtt aaacgtttgg tcaaggttat caaggatgtt gataagactc gctatgttac
    11521 catgggagca gataaattcc gtttcggtaa tggtagcgga gggcatgaga aaattgctga
    11581 tgaactcgat gctgttggat ttaactattc tgaagataat tacaaagccc ttagagctaa
    11641 gcatccaaaa tggttgattt atggatcaga aacatcttca gctacccgta cacgtggaag
    11701 ttactatcgc cctgaacgtg aattgaaaca tagcaatgga cctgagcgta attatgaaca
    11761 gtctgactat gggaatgatc gtgttggttg ggggaaaaca gcaaccgctt catggacttt
    11821 tgaccgtgac aacgctggct atgctggaca gtttatctgg acaggtacgg actatattgg
    11881 tgaacctaca ccatggcaca accaaaatca aactcctgtt aagagctctt actttggtat
    11941 cgtagataca gccggcattc caaaacatga cttctacctc taccaaagcc aatgggtttc
    12001 tgttaaaaag aaaccgatgg tacaccttct tcctcactgg aactgggaaa acaaagaatt
    12061 agcatccaaa gtagctgact cagaaggtaa gattccagtt cgtgcttatt cgaatgcttc
    12121 tagtgtagaa ttgttcttga atggaaaatc tcttggtctt aagactttca ataaaaaaca
    12181 aaccagcgat gggcggactt accaagaagg tgcaaatgct aatgaacttt atcttgaatg
    12241 gaaagttgcc tatcaaccgg gtaccttgga agcaattgct cgtgatgaat ctggcaagga
    12301 aattgctcga gataagatta cgactgctgg taagccagtg gcagttcgtc ttattaagga
    12361 agaccatgcg attgcagcag atggaaaaga cttgacttac atctactatg aaattgttga
    12421 cagccagggg aatgtggttc caactgctaa taatctggtt cgcttccaat tgcatggcca
    12481 aggtcaactg gtcggtgtag ataacggaga acaagccagt cgtgaacgct ataaggcgca
    12541 agcagatggt tcttggattc gtaaagcatt taatggtaaa ggtgttgcca ttgtcaaatc
    12601 aactgaacaa gcagggaaat tcacccttac tgcccactct gatctcttga aatcgaacca
    12661 agtcactgtc tttactggta agaaagaagg acaagagaag actgttttgg ggacagaagt
    12721 gccaaaagta cagaccatta ttggagaggc acctgaaatg cctaccactg ttccgtttgt
    12781 atacagtgat ggtagccgtg cagaacgtcc tgtaacctgg tcttcagtag atgtgagcaa
    12841 gcctggtatt gtaacggtga aaggtatggc tgacggacga gaagtagaag ctcatgtcaa
    12901 ggttctagca attgcgaaag aattaccaac agttaaacgt attgctccaa atactgactt
    12961 gaattctgta gacaaatctg tttcttatgt tttgactgat ggaagtgtac aagagtacga
    13021 agtagatagc tgggagatta cggaagtaga taaagccaaa ctttcagtag ctggatcacg
    13081 tattcaaatg actggtcagt tagctggaga aactattcat gcaacccttg tggtagaaga
    13141 aggaaatgct gcagcacctg tagtgccaac tgttactgtt ggaggtgaag cagtaacagg
    13201 tcttactagt cgacaaccaa tgcaatatcg tactctatct tatggtgccc aattgccaga
    13261 agtcacagca agtgctgaaa atgctgatgt gacagttctt caagcaagcg cagcaaacgg
    13321 catgcgtgcg agcatcttta ttcagcctaa agatggtggc cctcttcaaa cctatgcaat
    13381 tcaattcctt gaagaagcgc caaaaattgc tcacttgagt ttgcaagtgg aaaaagctga
    13441 cagtctcaaa gaagaccaaa ctgtcaaatt gtcggttcga gctcactatc aagatggaac
    13501 gcaagctgta ttaccagctg ataaagtaac cttctctaca agtggtgaag gggaagtcgc
    13561 aattcgtaaa ggaatgcttg agttgcataa gccaggagca gtcactctga acgctgaata
    13621 tgagggagct aaaggccaag ttgaactcac tatccaagcc aatactgaga agaagattgc
    13681 gcaatccatc cgtcctgtaa atgtagtgac agatttgcat caggaaccaa gtcttccagc
    13741 aacagtaaca gttgagtatg acaaaggttt ccctaaaact cataaagtca cttggcaagc
    13801 tattccgaaa gaaaaactag actcctatca aacatttgaa gtactaggta aagttgaagg
    13861 aattgacctt gaagcgcgtg caaaagtctc tgtagaaggt atcgtttcag ttgaagaagt
    13921 cagtgtgaca actccaatcg cagaagcacc acaattacca gaaagtgttc ggacatatga
    13981 ttcaaatggt cacgtttcat cagctaaggt tgcatgggat gtgattcgtc cagagcaata
    14041 cgctaaggaa ggtgtcttta cagttaatgg tcgcttagaa ggtactcaat taacaactaa
    14101 acttcatgtt cgcgtatctg ctcaaactga gcaaggtgca aacatttctg accaatggac
    14161 cggttcagaa ttgccacttg cctttgcttc agactcaaat ccaagcgacc cagtttcaaa
    14221 tgttaatgac aagctcattt cctacaataa ccaaccagcc aatcgttgga caaactggaa
    14281 tcgtaccaat ccagaagctt cagtcggtgt tctgtttgga gattcaggta tcttgagcaa
    14341 acgctccgtt gataatctaa gtgtcggatt ccacgaagac catggagttg gtgtaccgaa
    14401 gtcttatgtg attgagtatt atgttggtaa gactgtccca acagctccta aaaaccctaa
    14461 ttttgttggt aatgaggacc atgtctttaa tgattctgcc aactggaaac cagttactaa
    14521 tctaaaagcc cctgctcaac tcaaggctgg agaaatgaac cactttagct ttgataaagt
    14581 tgaaacctat gctgttcgta ttcgcatggt taaagcagat aacaagcgtg gaacgtctat
    14641 cacagaggta caaatctttg cgaaacaagt tgcggcagcc aaacaaggac aaacaagaat
    14701 ccaagttgac ggcaaagact tagcaaactt caaccctgat ttgacagact actaccttga
    14761 gtctgtagat ggaaaagtta cggcggtcac agcaagtgtt agcaacaatg gtctcgctac
    14821 cgtcgttcca agcgttcgtg aaggtgagcc agttcgtgtc atcgcgaaag ctgaaaatgg
    14881 cgacatctta ggagaatacc gtctgcactt cactaaggat aagagcttac tttctcataa
    14941 accagttgct gcggttaaac aagctcgctt gctacaagta ggtcaagcac ttgaattgcc
    15001 gactaaagtt ccagtttact tcacaggtaa agacggctac gaaacaaaag acctgacagt
    15061 tgaatgggaa gaagttccag cagaaaatct gacaaaagca ggtcaattta ccgttcgagg
    15121 ccatgtcctt ggtagtgatc ttgttgctga ggtcactgta cgagtgacag acaaactagg
    15181 cgaagctctt tcagataacc ctaactatga tgaaaacagt aaccaggcct ttgcttcagc
    15241 aaccaatgat attgacaaaa actctcatga ccgcgttgac tatctcaatg acggagatca
    15301 ttcagaaaat cgtcgttgga caaactggtc tccaacacca tcttctaatc cagaagtatc
    15361 agcgggtgtg atcttccgtg aaaatggtaa gattgtagaa cggactgttg cccaagccaa
    15421 acttcacttc tttgcagata gtggtacgga tgcaccaact aaactcgttt tagaacgcta
    15481 tgtcggtcca gagtttgaag tgccaaccta ctattcaaac taccaagcct acgacgcaga
    15541 ccatccattc aacaatccag aaaattggga agctgtgcct tatcgtgcgg ataaagacat
    15601 cgcagctggt gatgaaatca acgtaacatt taaagctgtc aaagccaaag ctatgagatg
    15661 gcgtatggag cgtaaagcag ataagagcgg tgttgcgatg attgagatga ccttccttgc
    15721 accaagtgaa ttgcctcaag aaagcacgca atcgaagatt cttgtagatg gaaaagaact
    15781 tgctgatttc gctgaaaatc gtcaagacta tcaaattacc tataaaggtc aacggccaaa
    15841 agtctcagtt gaagaaaaca atcaagtagc ttcaactgtg gtagatagtg gagaagatag
    15901 ccttccagta cttgttcgcc tcgtttcaga aagtggaaaa caagtcaagg aataccgtat
    15961 ccacttgact aaggaaaaac cagtttctga gaagacagtt gctgctgtac aagaagatct
    16021 tccaaaactc gaatttgttg aaaaagattt ggcctacaag acagttgaga aaaaagattc
    16081 aacactgtat ctaggtgaaa ctcgtgtaga acaagaagga aaaactggta aagaacgtat
    16141 ctttacagcg attaatcctg atggaagtaa ggaagaaaaa ctccgtgaag tggtagaagc
    16201 tccgacagac cgcatcgtct tggttggaac caaaccagta gctcaagaag ctaaaaaacc
    16261 acaagtgtca gaaaaagcag atacaaaacc aattgattca agtgaagcta gtcaaactaa
    16321 taaagcccag ttaccaaata caggtagtgc ggcaagccaa gcagcagtag cagcaggttt
    16381 agctcttcta ggtttgagtg caggattagt agttactaaa ggtaaaaaag aagactagaa
    16441 attttgatac cttctttatc attaaagacc aaagaaaaac tcttgtccta aatagaagat
    16501 aaagagtctg gaacaaaata gttctcaacc acaaaaaagc tagatatttc caattgtgga
    16561 actctagctt tttaattttg agtcgttctc ttattgtata gtagattgaa actagaatag
    16621 tacacttcta cttctaaaac attgttagaa atcgatttga ctgtccttat cgatttgtcc
    16681 tgttcttatt tcatttaact atattttagg aggttattgg ccataagtac caatcccatg
    16741 tcaattctca cttgacgctt gcccctcaga ttacatctct tgtaacccaa acaagccttt
    16801 atctgcccaa agacaggttc cacatcaatc ttgcgttgag cgaaaatctg tctaccttgg
    16861 ggagataaaa gcgcctgaca ttctttagct ttcaagtttt gatagcgttc gttcatatat
    16921 agtccccttt tgaggggctg attcaggttc gtcggcgtag taaaccttga tttcctgttg
    16981 aaagtctgtc tgtgttttct gatgtttggt atggtgaaaa cgataatacc agccatcagg
    17041 atgtgtgtag ctatcctcct tgtcattata gtgccaattc gctaagtttt tagctgactg
    17101 tttataccct ctcttttgtt ccttatcaaa catggcatat ttaatcagga ggggagtgat
    17161 ttcttcttga aaatagactt gtatctgttc ttgaagtttg gcggagaatt tctctgtcgt
    17221 tttcttccac acaaaactat acttgttggc attggcttca atcttagttc cgtcaataaa
    17281 caaacaatct aaggtcacta actcttccat ttttcaattt ttcgaccaga gaaaatccct
    17341 tgtgaatagg caaatagaag agtagataca agcattttag ggtgataaga cgggcgacca
    17401 aaggcatgat agaaggcgta gaagtgacgt tcctccaagg tattcaccac tttttcaata
    17461 gtaaagacga gatggtcttg tggtaagaag gaactgattt ttagtggtaa agttgtttga
    17521 tttgtgttat agtgaatatg catggaatag cctttctaaa tggtttattg ggcaattcta
    17581 ttttaccaag actatcgtaa ccatgcaaaa aaagcaacgg caaatccgtt gctttttttg
    17641 gagataagag actattgtcc cagactcttt tctttgtata aaattgtata gtgttattgt
    17701 ctatactatt ttgtagagaa agcaaaaatc cctagaaaat gcttagggat tcgactattt
    17761 cattaagaac aattcaacaa tcatttctat atacatgata agggttaata agaatcctgc
    17821 acgccagaag aatttgatga atttaggata gtaaaagctg cgttttttta aaaggaagaa
    17881 aaagacgaga ataatggcta ggaacgagag ggctagcccc agtctaggga ggaaattatg
    17941 ggtaaaggtt ttagctgtaa tcaagtaata ctcaaatacc aagactggaa aagccaaatc
    18001 cgcaaagttt cgtcctagtt tttttaatct aaaaagtttg gttaggataa tgcagacgac
    18061 taaggtcagt atcaataata aaatagatgc taatttcatt aaaatcatac ccatattgta
    18121 tcataaaaaa aggctaatgg aaacgagaaa cagaggaatt tataggaaag tcaggctttt
    18181 gagattgtgg gtgatttttg ttataatgaa agttataaaa tcttatgata ccttgaatga
    18241 ttattatcga aaactctttg gagaaaagac ttttaaagtc cctattgatg cgggatttga
    18301 ctgtcccaat cgtgatggaa ctgtggctca tggaggctgt actttttgta cggtttccgg
    18361 ttctggagat gccattgtgg caccagatgc gcctatccgt gagcaatttt ataaggaaat
    18421 tgactttatt catcgtaagt ggccagatgt tcagaagtat ctggtttatt ttcaaaattt
    18481 taccaacacc catgaaaagg tggaagttat tcgagagcgt tatgaacagg ctatcaatga
    18541 gccaggtgtg gtaggaatca atattggaac gcgcccagac tgtttaccag acgaaaccat
    18601 cgaatatttg gctgagttat cggagtgcat gcatgtgacg gttgaattgg gcttgcagac
    18661 tacttatgaa gcaacctctg acctgattaa ccgtgcgcat tcttatgaat tgtaggtgga
    18721 aacggtcaag cgtttgagaa agtatccaaa aattgagatt gtttcccatt tgatcaatgg
    18781 tttgcctggt gaaacccatg agatgatggt tgaaaatgtc cgccgttgtg tcacggataa
    18841 cgatattcaa gggattaaac tgcatttgct ccatcttatg acaaatactc gtatgcaacg
    18901 agattaccat gagggacgtt tacaattgat gagtcaggac gaatatgtca gggtcatctg
    18961 tgaccaactg gaaattattc ccaaacatat cgtcatccat cgaattacag gagatgcgcc
    19021 tagggatatg ctgattggtc ctatgtggag cctcaataaa tgggaagtcc tcaacagcat
    19081 tgagatggag atgagacgtc gtggaagtgt tcaaggatgc aaggctgtaa aacaggagtt
    19141 tgaaaatgaa aagaccactt gagatggcac atgatttttt ggctgaggtc gtgacaaaag
    19201 aggatgtcgt agtggatgcg actatgggaa atggtcatga cacgcttttt ttagccaagc
    19261 tagccaagca agtctatgcc tttgatattc agaagcaagc cttggaaaag acccaagagc
    19321 gtttgcatca ggctggcttg acaaatgccc agttaatctt gcaaggccat gagacactgg
    19381 accagtttgt gacaaaagct aaggcaggga tttttaattt gggctatttg ccgtcagctg
    19441 ataagtctgt catcacccga ccgcagacaa cgattgaggc attagaaaag ctatgtggct
    19501 tacttgtcaa aggtggacga attgctatta tgatttacta tggtcatgaa ggaggcgacc
    19561 tcgagagaga tgctgtcttg gattttgtga tccagttgaa ccaacaagag tacacagctg
    19621 ccatttaccg aactttaaac caagtcaaca acccgccgtt tttagtgatg attgaaaaat
    19681 tagagagata cagacatgga taaacaatac ctacacgaaa agctggatgc catgcgccag
    19741 aattttgttg aatcaaccta ccacgaacga gcggtgggcg tgctagacca agcgcatatg
    19801 agcaaaaaaa tgcttaaaat caagaaaaaa ttagttgctc ttgaaatgga acggtgccag
    19861 agaaaaattg agcacaaaga ctgttccaag attgaccaaa aaatcaaaga gcagaaggag
    19921 atatttgaat cctgttgtaa aaaagattaa ggaggacgtg cgtggaatta ctgatttacc
    19981 tcatcctatt tttactggtc ttgattgtct caagtacaac caataagctc ctaccctttt
    20041 tgcctctccc tttggtgcag attcttttgg gaattgtgat tggtctcttt ttacccaata
    20101 ctgactttca ccttaatacg gagttgtttt tggcactggt tatcggaccc ttgcttttcc
    20161 gagaggctga agaagcagat gttacggcta ttttaaaaca ctggcgaatc attgtttatc
    20221 tcatatttcc agtgattttt atctcgaccc tgagtttggg tggcttggcc catcttcttt
    20281 ggttcagcct tcccttggca gcttgcttgg ctgttggggc agcccttggt cctacggact
    20341 tggtggcctt tgcctctctt tcggagcgtt ttagctttcc taagcgcgtg tccaatattc
    20401 ttaagggcga aggactcttg aatgatgctt ctggtttggt ggcttttcag gtagctttga
    20461 cagcttggac aactggagct ttttctctgg ggcaagctag cagttcgctc atcttttcaa
    20521 tcctaggcgg ttttttaatt ggatttttaa cagccatgac caaccgcttc ctccatacct
    20581 tcttgctaag tgtgcgcgca acggatattg ccagtgaact tttattagaa ttgagtttgc
    20641 ctctagtgac cttctttctg gcagaagaag ttcatgtttc aggtattatt gccgtcgtag
    20701 ttgctggaat tttaaaggca agtcgcttca agaaaatcac gctcctcgaa gcccaagtgg
    20761 atacggtgac cgagacggtc tggcatacag tgacctttat gctcaacggt tctgtctttg
    20821 tgattttagg gatggagttg gaaatgatag cagaacctat cttgaccaat ccaatctata
    20881 atcctctact tttattgcta tctcttatcg cccttacctt tgtccttttt gtcattcgtt
    20941 ttattatgat ctatggctat tatgcctata gaacccgacg cctcaagaaa aagctaaata
    21001 agtatatgaa ggacatgttt ctcttgacct tttcaggtgt taagggaacg gtgtcgattg
    21061 ctacgattct cttgatacca agtaatctag aacaggagta tcctcttttg cttttccttg
    21121 ttgcaggtgt gacgcttgtt agctttttaa caggtctctt ggtcttgcct catctttctg
    21181 atgaagagga agaaagcaag gattatctta tgcatatcgc cattttgaat gaagtaacgc
    21241 tagagttgga aaaagagttg gaagacacca gaaataaact tcccctctat gcggctattg
    21301 acaattatca tggacgtatt gaaaatctca ttttaagcca agaaaaccag gatgatcaag
    21361 aagactgggc tgctttgaaa ctcttgattc ttagtattga aagtgatggt ttggagcagg
    21421 cctatgaaga ggggaacatt agcaatcgtg cttaccgagt ttaccaacgt tatctgaaaa
    21481 atatagaaca aggaatcaat cgtaaacttg cctcaagact gacctattat ttccttgttt
    21541 ctttgcggat tttacgtttt ctccttcatg aagtttttac tctcggaaag accttccgta
    21601 gctggaagaa caaggagcaa agccgtctcc gtgctcttga ttatgaccaa attgcagagc
    21661 tctatcttgc caatacggag atgattattg aaagtttgga aaacctgaag ggagtctaca
    21721 gacgctcttt gattagtttt atgcaggagt ctcgtcttcg agaaacaact attatcagca
    21781 gtggtgcctt tgtcgaacgg gttatcaatc gtgtcaaacc caacaatatc aatgaaatgc
    21841 tgagaggcta ttatctggag cgcaagttga ttttcgaata cgaagaaaaa cgattaatta
    21901 caactaagta tgccaagaaa ttacgacaaa atgtaaataa cttagagaac tattccttga
    21961 aggaagctgc caataccctg ccgtatgata tggtggaatt ggtaagaaga aattagttaa
    22021 tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt atgtgactga
    22081 cttcgtcagt cttatctaca acctcaaaac agtgttttga gcagcttgcg gctagctttc
    22141 tagtttgctc tttgattttc attgagtata agattataaa tgaaggagta tgacatgaaa
    22201 aagtggtgga aagagctgat agacaagcct ttattaaaag cttttttgca ttattatcaa
    22261 gcatcagata gtgagttgac cagtgtcgca gtagcctact attggttgat ttcgattttc
    22321 cccctgcttt tggtggtggt caatatcctc ccctattttc agattcctgt gggagaattt
    22381 ctgggcttta tgaaagacgt cctgccccca agcctctatg aaggtgtgga aaaaatagcc
    22441 agagaagtct tgacgcaacc ttcaacaggt ttattgagtt tttctgtttt atcggcgtta
    22501 tggagttttt caaaatctat gaatttcttg caaaaagctt ttaacaaggc ttatggcgtc
    22561 gaaaagagtc gtggacttat ttcccatcag atgctaagtc tcctagtcag ttttggcttg
    22621 cagctcctct ttgcgtttgc cttgtttttg attttatttg gtcagatgat tttggcttta
    22681 cttgctcatt attggacaaa agatggcatt atctatcagg ctttacaagg gttggcaggt
    22741 cctctgattt acgccctcct ctttgctatc ttggtcatgc tttattattt tcttcccaat
    22801 ctatctaaca ggaaaattag ctatacccta ccaggcagtg cctttgttct cttagtgatt
    22861 ttaggtttac taactctgtt ctctagttat ctcaattact atgtccatca tttggtggat
    22921 gtccgaattt taggttccgt tcttcttgtt gttatgatgt tttggtttat cttgattgct
    22981 aaaattgtta tcctaggcgc ggttatcaat gccagtatgc agagtttgaa agatccggtc
    23041 tttaaaaaag actaactatt tatccattat aaaagcgcat agtatcaaga ctttatagaa
    23101 ccttgatact atgcgctttt gtgctttgac agttttttgt atagtttttg tccaagattt
    23161 ctaaatcatc tgattaaatt cctattttcc cctatcattg tccctgtttt ttcgaaaatg
    23221 gaaggagtat aataaatcta tcaataaaat gataggagga actttatggg tcatattttc
    23281 ttttttctaa gtgtcttttt ggcagggatt ctatccttct tttctccttg tatcttacct
    23341 ttgttaccgg tctatacagg agtgttacta gatgataagg atggtgctca ggcttctagc
    23401 ggcaaatttt caatctcagt tactagttta ttacgaactc tggcctttat agcaggaatt
    23461 tcctttatat ttattttgtt gggctatgga gctggttttt taggcgattt gctttatgct
    23521 tcttggttcc aatatcttac tggggcaatt attatccttc ttggtttgca ccaaatggag
    23581 attctacact ttaaggggct ttataaggaa aagaggctac aactgcaagg acaggggcaa
    23641 aatggtaagg gctatagtca ggcattttta ttgggcttga cctttagttt tgcttggacg
    23701 ccttgcgtgg ggccggttct ggggtctgtt ttggccttgg cggcttcagg tggttcagga
    23761 gcttggcagg gagctggtct catgttggtg tatacgctgg gcttggcgct accattcttg
    23821 cttctagctc tgacctctag ttatgttttg aaacatttcc gaaaacttca tccctatctc
    23881 ggaatcctca aaaaagtggg tggttttctc attattgtga tgggactctt ggttctgttt
    23941 ggaaatgctt caattttaag tcaattattt gaataaaatg gaaaggaata tcaatatgaa
    24001 aaaatggcaa acatgtgttc ttggagcagg ttcgctcctt tgtttgacgg cttgttcagg
    24061 caagtccgtg actagtgaac accaaacgaa agatgaaatg aagacggagc agacagctag
    24121 taaaacaagc gcagctaaag ggaaagaggt ggctgatttt gaattgatgg gagtagatgg
    24181 caagacctac cgtttatctg attacaaggg caagaaagtc tatctcaaat tctgggcttc
    24241 ttggtgttcc atctgtctgg ctagtcttcc agatacggat gagattgcta aagaagctgg
    24301 tgatgactat gtggtcttga cagtagtgtc accaggacat aagggagagc aatctgaagc
    24361 ggactttaag aattggtata agggattgga ttataaaaat ctcccagtcc tagttgaccc
    24421 atcaggcaaa cttttggaaa cttatggtgt ccgttcttac ccaacccaag cctttataga
    24481 caaagaaggc aagctggtca aaacacatcc aggattcatg gaaaaagatg caattttgca
    24541 aactttgaag gaattagcct aggaggtgtc ttatgaatga taagttaaaa atcttcttgt
    24601 tgctaggagt attttttcta gccataaccg gtttctatgt tctattgata cgaaatgcag
    24661 ggcagacaga tgcctcgcaa attgaaaagg cggcagttag ccaaggagga aaagcagtga
    24721 aaaaaacaga aattagtaaa gacgcagact tgcacgaaat ttatctagct ggaggttgtt
    24781 tctggggagt ggaggaatat ttctcacgcg ttcccggggt gacggatgcc gtttcaggct
    24841 atgcaaatgg tagaggagaa acaaccaagt acgaattgat taaccaaaca ggtcatgcag
    24901 aaaccgtcca tgtcacctat gatgccaagc aaatttctct caaggaaatc ctgcttcact
    24961 atttccgcat tatcaatcca accagcaaaa ataaacaagg aaatgatgtg gggacccagt
    25021 accgtactgg tgtttattac acagatgaca aggatttgga agtgattaac caagtctttg
    25081 atgaggtggc taagaaatac gatcaacctc tagcagttga aaaggaaaac ttgaagaatt
    25141 ttgtggtggc tgaggattac catcaagact atctcaagaa aaatccaaat ggctactgcc
    25201 atatcaatgt taatcaggcg gcctatcctg tcattgatgc cagcaaatat ccaaaaccaa
    25261 gtgatgagga attgaaaaag accctgtcac ctgaggagta tgcagttacc caggaaaatc
    25321 aaacagaacg agctttctca aaccgttact gggataaatt tgaatccggt atctatgtgg
    25381 atatagcaac tggggaacct ctcttttcat caaaagacaa atttgagtct ggttgtggct
    25441 ggcctagttt tacccaaccc atcagtccag atgttgtcac ctacaaggaa gataagtcct
    25501 acaatatgac gcgtatggaa gtgcggagcc gagtaggaga ttctcacctt ggccatgtct
    25561 ttacggatgg tccacaggac aagggcggct tacgttactg tatcaatagc ctctctatcc
    25621 gctttattcc caaagaccaa atggaagaaa aaggctacgc ttatttacta gattatgttg
    25681 attaatactc ttcgaaagtc tcttcaaacc acgtcagcgt cgccttaccg tatgtagggt
    25741 tactgacttc gtcagtttta tctacaacct caaagctata ctttgagctg acttcgtcag
    25801 ttttatctac aacctcaaag ctatactttg agctgacttc gtcagtttta tctacaacct
    25861 caaagcggta ctttgagaaa cctgtggcta tcttcctagt ttactttttg atttttattg
    25921 agtataagag gtctttccta agcagttaga ggagaatttt gctatactga tactagtaag
    25981 tggtaaagga gcagagcatg acctacacaa tcttaatcgt agaagatgaa tatctggtaa
    26041 gacaaggttt gactaaactg gtcaatgtag cagcctacga tatggaaatc atcggtcagg
    26101 ctgaaaatgg aaggcaggct tgggaattga tccaaaagca ggtgccagat atcattttaa
    26161 ccgatatcaa catgcctcat ctaaatggca tccagttggc cagtctggta cgagaaacct
    26221 atcctcaggt tcatttggtc tttttaacag gttacgatga ttttgattat gccttgtctg
    26281 ctgtcaaact aggtgtggac gactacctgc tcaaaccctt ttctcgtcag gatattgagg
    26341 aaatgttggg gaaaatcaaa caaaaactag acaaggaaga gaaagaagag cagttacaag
    26401 atttattgac taataggttt gaaggaaaca tggcccagaa aatccagtct catctggctg
    26461 atagccaatt tagtttaaag tctttagcca gtgacttagg ttttagtccg acctatctga
    26521 gttccttgat taagaaagag ttgggcttgc cttttcagga ttatctggtg agagaacgtg
    26581 ttaaacaagc caagctcttg cttttaacta cagatctgaa gatttatgag atcgcagaga
    26641 aggttggttt tgaagatatg aactatttta cccaacgttt taagcagatt gcaggtgtga
    26701 cacctcgtca gtttaagaag ggagaagacc gatgaagcgt tcttctcttt tagttagaat
    26761 ggttatttcc atctttctgg tctttctcat tctcctagct ctggttggaa ctttctacta
    26821 tcaatcaagt tcttcagcca ttgaggccac cattgagggc aacagccaaa cgaccatcag
    26881 ccagactagc cactttattc agtcttatat caaaaaacta gaaaccactt cgaccggttt
    26941 gacccagcag acggatgttc tgacctatgc tgagaatccc agtcaagaca aggtcgaggg
    27001 aatccgagat ttgtttttga ccatcttgaa gtcagataag gacttgaaaa ctgttgtgct
    27061 ggtgaccaaa tctggtcagg tcatttctac agatgacagt gtgcagatga aaacttcctc
    27121 tgatatgatg gctgaggatt ggtaccaaaa ggccattcat cagggagcta tgcctgtttt
    27181 gactccagct cgtaaatcag atagtcagtg ggtcatttct gtcactcaag aacttgttga
    27241 tgcaaaggga gccaatcttg gtgtgcttcg tttggatatt tcttatgaaa ctctggaagc
    27301 ctatctcaat caactccagt tggggcagca gggctttgcc ttcattatca atgaaaacca
    27361 tgaatttgtc taccatcctc aacacacagt ttatagttcg tctagcaaaa tggaggctat
    27421 gaaaccctac atcgagacag gtcagggtta tactcctggt cacaaatcct acgtcagtca
    27481 ggagaagatt gcaggaactg attggacggt acttggcgtg tcatcattgg aaaagttaga
    27541 tcaggttcgg agtcagctct tgtggacctt gcttggggcc agtgtcacat ctcttcttgt
    27601 ctgtctctgc ttagtgtggt tcagtcttaa acgctggatt gctcctttga aggatttgag
    27661 agaaaccatg ttggaaattg cttctggtgc tcaaaatctt cgtgccaagg aagttggtgc
    27721 ctatgaactg agagaagtaa ctcgccaatt taatgccatg ttggatcaga ttgatcagtt
    27781 gatggtagct attcgtagcc aggaagaaac gacccgtcag taccaacttc aagccctttc
    27841 gagccagatt aatccacatt tcctctataa cactttggac accatcatct ggatggctga
    27901 atttcatgat agtcagcgag tggtgcaggt gaccaagtcc ttggcaacct atttccgctt
    27961 ggcgctcaat caaggcaagg acttgatttg tctctctgac gaaatcaatc atgtccgcca
    28021 gtatctcttt atccagaaac aacgctatgg agataagctg gaatacgaaa ttaatgaaaa
    28081 tgttgccttt gataatttag tcttacccaa gctggtccta caaccccttg tagaaaatgc
    28141 tctttaccat ggcattaagg aaaaggaagg tcaaggccat attaaacttt ctgtccagaa
    28201 acaggattcg ggattggtca tccgtattga ggatgatggc gttggcttcc aagatgctgg
    28261 tgatagtagt caaagtcaac tcaaacgtgg gggagttggt cttcaaaatg tcgatcaacg
    28321 gctcaaactt cattttgaag ccaattacca gatgaagatt gattctagac cccaaaaagg
    28381 gacgaaagtt gaaatatata taaatagaat agaaactagc taactcccag tcaattctgg
    28441 gagttttatg cgtaattggg caaactttat aggttgtcta tcttgctaaa aacaagaaaa
    28501 aacggtatga tagaagagtg acaacagagg taacagagat gaacgagaca cagattcaaa
    28561 gagaaacacg tcaggtagtg gaagatgttt tagaaaagac caatttgaag cagggggtcc
    28621 tttttgtttt aggtctatct tctagtgagg tgctaggtgg tcagattggg aaagaatcca
    28681 gtcaagagat tggtgagctg atagtggaga ctatcttggg tattctaggt agtagaggta
    28741 tccatttagc agttcaaggt tgtgagcatg tcaatcgggc tctcgttgtt gaacgtcagg
    28801 tggcagagca gtttgatctg gaaattgtca gtgtccatcc tactcttcat gcaggaggtt
    28861 cggggcagtt ggcagccttt aagtttatgc aggatccagt tgaggttgaa tttatcaagg
    28921 ctcatgctgg attggatatc ggagacactg caattggcat gcatgtcaag catgttcagg
    28981 ttccgattcg ccctattttg agagagattg gtcatgccca tgtaacggca ctggctagtc
    29041 gtccaaaatt aatcggaggt gcgcgtgcgc actatccgca agatgctatt agaaagtctt
    29101 gagaatgaat aaaggagatg aaagtgttta aaaaagaccg tttttcaatt cgtaagatta
    29161 agggagttgt aggctctgta tttcttggaa gccttttgat ggctccttct gtagtggacg
    29221 cagctaccta tcactatgta aataaagaga ttatttcaca agaagctaaa gatttaattc
    29281 agacaggaaa gcctgacagg aatgaagttg tatatggttt ggtgtatcaa aaagatcagt
    29341 tgcctcaaac agggacagaa gcatctgttt tgacagcttt tggtttgctg actgttggga
    29401 gcttgctttt aatctacaag agaaagaaaa ttgctagcgt ctttctagtt ggagctatgg
    29461 gattggtagt tcttcctagt gcagaggctg tagacccagt tgcgacccta gcgctggcta
    29521 gtcgagaggg tgttgttgaa atggatggct atcgctatgt tggttatcta tcaggtgaca
    29581 tcctcaaaac gcttggcttg gacactgttt tagaagaaac ctcagcaaaa cctggagagg
    29641 tgactgtagt cgaagttgag actcctcaat caacaacaaa tcaggagcaa gctaggacag
    29701 aaaaccaagt agtagagaca gaggaagctc caaaagaaga agcacctaga acagaagaaa
    29761 gtccaaagga agaaccaaaa tcggaggtaa aacctactga cgacaccctt cctaaagtag
    29821 aagaggggaa agaagattca gcagaaccag ctccagttga agaagtaggt ggagaagttg
    29881 agtcaaaacc agaggaaaaa gtagcagtta agccagaaag tcaaccatca gacaaaccag
    29941 ctgaggaatc aaaagttgaa caagcaggtg aaccagtcgc gccaagagaa gacgaacagg
    30001 caccagtcga gccagaaaag caaccagaag ctcctgaaga agagaaggct gtagaggaaa
    30061 caccgaaaca agaagagtca actccagata ccaaggctga agaaactgta gaaccaaaag
    30121 aggagactaa aacagctaag gggacgcaag aagaaggcaa agaaggtcaa gcaccagtac
    30181 aagaagtaaa cccagaatat aaagtaacaa caggtacagt tgagaagtct accgaaagtg
    30241 aattagattt cacaacagaa gtagttccgg atgacacaaa atatgtagat gaagaagttg
    30301 ttgaacgtca aggatctaaa ggagttcaag ttacgaaaac aacttacgaa acagtggaag
    30361 ttgtagagac agacaaagtc ctttctacaa ctacagaagt gaaaactcct gttgttccta
    30421 aagtcgttaa aaaaggaaca aaaccagttg aaggaacagc agttgaaaca agagaagaag
    30481 tcattccttt tgctacaaaa gaacaagaag atgacacttt aaaacgcgga acaagacaag
    30541 tagctcaaga aggtgtaaac ggtaagaaac aaattactga aacctataaa acaattcgcg
    30601 gagaaaaaac aaacgaagct ccaacagtag aagaaacagt tctccaagca cctcaagatg
    30661 agattatcaa aaaaggcaca aaaggtttag aaaaaccaac cttagaatgg gttaaaacag
    30721 ataaagatgt cttgaagaag agtgcgacag ccagttatac attgaataaa ccagatgggg
    30781 tagaaatcaa atccatcaaa gtagctctaa aagataatac tggaacagtt attaaagaag
    30841 taacggtaga agaaaataac ttaaacgcta ctttagacaa cttgaaatat tatcaaggtt
    30901 atacactatc cacaaccatg gtctataatc gaggcgaagg cgaagaaact gaaatgttag
    30961 aagataaaga agttcagtta gaccttaaaa aagttgaaat caaatccatc aaagaaacta
    31021 gcttgatgag tgtggatgat gctggtgttg aaacagataa gagcttactt actgaaaaac
    31081 cgacagacgt tgctccactt tacctacgag tgacaactca tgataacaaa acaacaagac
    31141 tggcagtaag ttcagttgaa gaagttgttg ttgatggaaa aacattgtac aaagtggtag
    31201 ctaaagctcc tgacttagtt caacgtagag aagatgatac actaagcgaa gagtatgtac
    31261 attactttga aaaacaatta ccaaaagtag ataatgtgta ctacaacttc aatgaacttg
    31321 taaaagatat gcaagctaat ccaacgggtg agtttaaact tggtgcagat ttgaatgcag
    31381 ttaacgttaa gccagcaggt aaagcttatg ttatggctaa atttagaggt actttatcaa
    31441 gtgtagagaa tcatcagtac acgattcata acttagaaag acctttgttt aatgaggctg
    31501 aaggtgctac actcaaaaac tttaacttag gtaatgtaaa tataaacatg ccttgggctg
    31561 ataaagttgc acctattggt aatatgttta agaagtctac acttgagaat atcaaagtag
    31621 tgggttcagt aacaggaaat aacgatgtaa ccggtgctgt taataagtta gacgaagcta
    31681 atatgcgcaa tgtagctttt attggcaaga ttaacagtct tggagataaa ggctggtggt
    31741 ctggtggact tgtcagcgaa agttggcgaa gtaacacgga tagtgtttat tttgacggtg
    31801 atattgtagg taacaattct aagtttggtg gtttagtagc taaagtcaat cacggaagta
    31861 atcagtggga tgttaaacaa aaaggtcgtt tgacaaattc tgttgttaaa ggtactatga
    31921 ctctgaaaaa tcatggtcaa agtggtggtt tagttcacga aaactatgac tggggttggg
    31981 ttgagaataa tattagtatg atgaaagtca ataacggtga aattatgtat ggttcaggtt
    32041 ctattgacgg tgacccatac tttggttttg actacttcaa aaataattat tatgtaaaag
    32101 atgttgctac tggagaaagt acctacaagc gttcgaaaca gattcagtct atctctcaag
    32161 ccgaagcaga cgccaaaatc gctaatatgg ggattactgc gaataccttc gctattcaag
    32221 atccagttgt aaacaagtta aatcgtatca ttgatagaga ttctgaatat aaagcgattc
    32281 aggactacca agaaacaaga aacctagctt atcgaaactt ggaaaaactt caaccgttct
    32341 ataataaaga gtggattgta aaccaaggga ataagttaac agatgagtcc aatcttgtta
    32401 agaaaaccgt tctgtctgta acgggtatga aatcagggca atttgttact gatttatcaa
    32461 gtgtggataa aatcatgatt cactatgccg atggaaccaa agaagaattt ggggtatctg
    32521 cgatttcgga ctctagggta aaacaagtca aagaatataa tgtagatgat ttaggtgtag
    32581 tttacactcc taatatggtt gataagaaca gagattcttt gattacgaaa gttaaagaga
    32641 agttgagttc tgttgcttta gactctgctg aggttaaatc tattacaaat aaccctgcat
    32701 ctctatacct agaagaaagt ttcgctgagg ttagagagac gttagataag ttagtgaagt
    32761 ccttgttaga aaatgaagat catcaactga acagtgatga agtggctgag aaggcgcttc
    32821 tcaagaaagt tgaagataat aaagctaaga ttatattagc cttgacttat ctaaatcgtt
    32881 attatggtat cgactatgat ggcttgaact ttaagcattt gatgatgttt aaaccagact
    32941 tttatggtaa aacaccaagt attttagatt tcttgattcg tataggttca gcagaaaaga
    33001 atttaaaagg agatagaagt ttagaagctt atcgtgaagt tattggtggt actattggaa
    33061 aaggggaatt aaatggcttg ttaggttata acatgcgttt attcactaag tacactgact
    33121 taaatgattg gtttattcat gctgcaaaga acgtttatgt ttctgagcct gagacgacta
    33181 cagaggattt caaagacaag cgccatcgta tctatgacgg tttgaataat gatgttcacg
    33241 gtcgtatgat tttaccgtta ttgaatttga aaaaagcgca tatttttgtg atttcgactt
    33301 acaatacaat agcctttagt tcctttgaaa aatatggtaa gaatacagaa gaagagcgga
    33361 acgcttataa agctgagatt gatagggttg caaaagcaca acaacgttac ttagacttct
    33421 ggtctcgttt agctttaccg aaagttcgca atcaactttt gaagagtcaa aactctgtac
    33481 caactcctgt ttgggataat caagtttatg taggtttagg tggtgcaaac cgtatgggtt
    33541 acggtgatgg gggtcgagta gtaactccag ttcgtgaatt attcggcccg actgatcgtt
    33601 ggcaccaaat aaactggaat atgggagcga tggcgaagat ttatgaacgt ccttggaaag
    33661 atgatcaagt ttatttcatg gttacaaata tgatggagcc gttcggtatc tcagccttta
    33721 cccatgaaac tactcacgtc aatgatagaa tggcttacta cggtggagat tggcaccgtg
    33781 aaggtacgga tttagaagcc tttgctcaag gcatgttgca aacacctgat aagtcaacaa
    33841 ccaatggtga atacggtgct ctcggtatca atatggctta tgagcgtaaa aatgatggtg
    33901 aacagcttta caattatgac cctgagaagt tagatagtag agagaaaatt gatagttaca
    33961 tgaagaacta caatgagtct atgatgatgc ttgactactt agaagctagt gcagttattc
    34021 gtcaaaattt gtctgataat tctaagtggt tcaagaagat ggataaagag tggcgcacta
    34081 atgcagatag aaaccgttta attggagaac cgcatcagtg ggataaatta cgtgatttaa
    34141 cagaagaaga gaagaagtta cctattgaca gtattgacaa gttggtagag aataactttg
    34201 taactcttca tggtatgccg aagaacggtc gttaccgcac agaaggtttt gatagctctt
    34261 atcaacctgt aaacatgatg gcaggtgtct ttggagggaa tacaagtaaa agcaccgtag
    34321 ggtctatttc atttaaacat aatgctttcc gtatgtgggg atactatgga tatgaaaatg
    34381 gctttattcc ttatgtttct aacaagttaa aaggtgctgc aaataaagag aataaagggc
    34441 ttttaggtga tgatttcatt atcaagaaag tttctaagaa tcaattccaa aatctcgaag
    34501 agtggaagaa gcattggtat catgaagttt atgataaagc acaaaaaggc tttgttgaga
    34561 ttgaggtaga cggagtgaaa atttcaacgt atgctcagtt acaatcctta tttgaagaag
    34621 ctgttagcaa agatcttgca ggtatggatg ataagaacat taagaatcat taccaatata
    34681 cagagaatct caagtggaaa atatacaaac aactccttaa aaacacagac ggtttctcta
    34741 gtgatctatt tactgcacca caagcatagg gatgaa
//
LOCUS       DAVLZS010000020        33768 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLZS010000020 DAVLZS010000000
VERSION     DAVLZS010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.020"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(223..585)
                     /locus_tag="VYO88_001022"
     CDS             complement(223..585)
                     /locus_tag="VYO88_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1719136.1"
                     /translation="MLEVGLNSLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            593..673
                     /locus_tag="VYO88_001023"
                     /pseudo
     CDS             593..673
                     /locus_tag="VYO88_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(1382..2071)
                     /gene="rplA"
                     /locus_tag="VYO88_001024"
     CDS             complement(1382..2071)
                     /gene="rplA"
                     /locus_tag="VYO88_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1719137.1"
                     /translation="MAKKSKQLRVALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2279..2704)
                     /gene="rplK"
                     /locus_tag="VYO88_001025"
     CDS             complement(2279..2704)
                     /gene="rplK"
                     /locus_tag="VYO88_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1719138.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2836..2973
                     /locus_tag="VYO88_001026"
     CDS             2836..2973
                     /locus_tag="VYO88_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719139.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDVVS
                     R"
     gene            complement(3013..3729)
                     /locus_tag="VYO88_001027"
     CDS             complement(3013..3729)
                     /locus_tag="VYO88_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEV1719140.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAADYPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3747..4208)
                     /locus_tag="VYO88_001028"
     CDS             complement(3747..4208)
                     /locus_tag="VYO88_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1719141.1"
                     /translation="MCLICQRIELIKAGENPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KEHVTELHQMENSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGNMKGHGLNGRGPVWWVPWEEMAAEDCQVQSPEREEMIKILSHELEKHLA"
     gene            complement(4210..5247)
                     /locus_tag="VYO88_001029"
     CDS             complement(4210..5247)
                     /locus_tag="VYO88_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1719142.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KNQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSEAVS"
     gene            complement(5345..6670)
                     /gene="brnQ"
                     /locus_tag="VYO88_001030"
     CDS             complement(5345..6670)
                     /gene="brnQ"
                     /locus_tag="VYO88_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1719143.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6841..6932)
                     /locus_tag="VYO88_001031"
                     /pseudo
     CDS             complement(6841..6932)
                     /locus_tag="VYO88_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(6975..7127)
                     /locus_tag="VYO88_001032"
     CDS             complement(6975..7127)
                     /locus_tag="VYO88_001032"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1719144.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(7287..7865)
                     /locus_tag="VYO88_001033"
     CDS             complement(7287..7865)
                     /locus_tag="VYO88_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1719145.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7919..9319)
                     /gene="pepV"
                     /locus_tag="VYO88_001034"
     CDS             complement(7919..9319)
                     /gene="pepV"
                     /locus_tag="VYO88_001034"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1719146.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9332..9937)
                     /locus_tag="VYO88_001035"
     CDS             complement(9332..9937)
                     /locus_tag="VYO88_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1719147.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            10108..10908
                     /locus_tag="VYO88_001036"
     CDS             10108..10908
                     /locus_tag="VYO88_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1719148.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIVFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11090..11923)
                     /locus_tag="VYO88_001037"
     CDS             complement(11090..11923)
                     /locus_tag="VYO88_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1719149.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGP
                     GANDLVALLKELPITASVRGNWDDCVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKDFFDF
                     L"
     gene            complement(11913..13760)
                     /gene="uvrC"
                     /locus_tag="VYO88_001038"
     CDS             complement(11913..13760)
                     /gene="uvrC"
                     /locus_tag="VYO88_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1719150.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(13800..14501)
                     /locus_tag="VYO88_001039"
     CDS             complement(13800..14501)
                     /locus_tag="VYO88_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1719151.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14580..15812)
                     /gene="murN"
                     /locus_tag="VYO88_001040"
     CDS             complement(14580..15812)
                     /gene="murN"
                     /locus_tag="VYO88_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1719152.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNSIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15817..17037)
                     /gene="murM"
                     /locus_tag="VYO88_001041"
     CDS             complement(15817..17037)
                     /gene="murM"
                     /locus_tag="VYO88_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1719153.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17149..17928)
                     /locus_tag="VYO88_001042"
     CDS             complement(17149..17928)
                     /locus_tag="VYO88_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1719154.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKQALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17997..19658)
                     /locus_tag="VYO88_001043"
     CDS             complement(17997..19658)
                     /locus_tag="VYO88_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1719155.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19833..22055)
                     /gene="recJ"
                     /locus_tag="VYO88_001044"
     CDS             complement(19833..22055)
                     /gene="recJ"
                     /locus_tag="VYO88_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1719156.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22332..23090
                     /locus_tag="VYO88_001045"
     CDS             22332..23090
                     /locus_tag="VYO88_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1719157.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTLNGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAILSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            23130..23894
                     /locus_tag="VYO88_001046"
     CDS             23130..23894
                     /locus_tag="VYO88_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1719158.1"
                     /translation="MISLFGLAAAKPVQADTNIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDTFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23907..24584
                     /locus_tag="VYO88_001047"
     CDS             23907..24584
                     /locus_tag="VYO88_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1719159.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAVGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24594..25253
                     /locus_tag="VYO88_001048"
     CDS             24594..25253
                     /locus_tag="VYO88_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1719160.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVPVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25502..26692
                     /locus_tag="VYO88_001049"
     CDS             25502..26692
                     /locus_tag="VYO88_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1719161.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27013..27894)
                     /locus_tag="VYO88_001050"
     CDS             complement(27013..27894)
                     /locus_tag="VYO88_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1719162.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28035..29363)
                     /gene="vncS"
                     /locus_tag="VYO88_001051"
     CDS             complement(28035..29363)
                     /gene="vncS"
                     /locus_tag="VYO88_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1719163.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(29360..30016)
                     /gene="vncR"
                     /locus_tag="VYO88_001052"
     CDS             complement(29360..30016)
                     /gene="vncR"
                     /locus_tag="VYO88_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1719164.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30065..30148)
                     /gene="pep27"
                     /locus_tag="VYO88_001053"
     CDS             complement(30065..30148)
                     /gene="pep27"
                     /locus_tag="VYO88_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1719165.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(30328..31707)
                     /gene="vex3"
                     /locus_tag="VYO88_001054"
     CDS             complement(30328..31707)
                     /gene="vex3"
                     /locus_tag="VYO88_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1719166.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31759..32406)
                     /gene="vex2"
                     /locus_tag="VYO88_001055"
     CDS             complement(31759..32406)
                     /gene="vex2"
                     /locus_tag="VYO88_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1719167.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32419..33696)
                     /locus_tag="VYO88_001056"
     CDS             complement(32419..33696)
                     /locus_tag="VYO88_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1719168.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9600 a         7708 c         6263 g        10197 t
ORIGIN      
        1 taaactaacc tcctcattat tagcaaggct tctactgatt ataacctaat tcttagacta
       61 cttcaagact aactgtccaa taataatcta cagataaatc atccactctt aatcaaattt
      121 tattcaatcc atctactcat tcccaaaagg ttgctgtata atgcaagaca tttttcttac
      181 tgcttttact tttccttacc ctcaatttag tgagctaata aattattctt cttcaaaagg
      241 ttgagattta tctagtaact ctaaaacatt aatggtaggt agcaacattg cttcactgct
      301 atcaattgcc gaaactattg aaacaataga acgtaaataa ggataaagaa tagcagtacc
      361 atttacgtat agaatatcgg tgatattttc atctatattt atttcaaaat atcctattac
      421 agttacagat atttttttca tggcatcttt gtcaactaaa gaaacactaa gttttacggc
      481 tccatgacta taatcatctg tatgaccaac cttaactatg ggatataata tatcgaaggt
      541 aaatgtgaac aaactgatta gggaatttaa accaacttct aacaatgtgt tatactcaat
      601 gaaaaccaaa gagcaaacta ggaaactagc cgcaggttgc tcaaaacact gttttgaggt
      661 tgtagatgga actgacgtag tcagctcaaa acactgtttt gaggttgtgg atagaactga
      721 cgaagtcagt aaccatacgc acggcaaggc gacgttgacg tggtttgaag agattttcga
      781 agagtattag aaagctcgat ggactattcc agattcattc cactagattt cgaaatcgag
      841 taggggataa tctctagccc ctctcacacc accgtacgtg ccgttcggca tacggcggtt
      901 caactaactg ttaacgcatg tcgttcaagg taataatcca aacacgaaac cagtccacgt
      961 ttttcaagga ctggttttga tatagcacgt ttaagtaccg acttctgagc tactatagta
     1021 gattgaaact agaatagtac atctcttctt ctaaaacatt gttagaaatc gatttggctg
     1081 ccctgatcga ttcgtcctac tcttatttca ttttactata attgatagtg gtcgccccag
     1141 ccagatacct tatccgctat ataggcctta ttatcatgtt cctgttcgta gagccacgat
     1201 ttcgctatcc cttcctctga cgattcttat ttcctgcgtc agacttggga atcgctattg
     1261 ggttcaccgg tagcaggtgc ccaccgagga cttacacctc agatatacga catgcccgtc
     1321 gtacatcaaa aaaagttgag acatagcgtc ttcaactttt ttacattact ttaactactg
     1381 attaaagtga gtttacatca actttgatac caacaccttg agtagttgtg atagtcaagt
     1441 ttgttacgta agttccttta gctgtagctg gttttgcttt ttggattgtt tcgttgaaag
     1501 ctttaaagtt ttcaaccaat ttttcagctt caaatgatac tttaccgatg attgcttgaa
     1561 cgttacctgc acggtcagca cggtaagtga ttttaccacc tttagactct tcaactgctt
     1621 tagcaacatc cattgttaca gtaccagttt tagggtttgg catcaagtta cgtggtccaa
     1681 ggacacgtcc aagacgtcca acaagagcca tcatatcagg tgtagcgata actacgtcga
     1741 agtccaacca accgtcgttg attttagcaa caaggtcatc ttcaccaaca aagtctgcac
     1801 cagcagcttt tgcttcttca gcttttgcac cacgtgcgaa aacaagaaca cgtgaagttt
     1861 taccagtacc gtttggcaat accattgctc cacggatttg ttggtcagct tttttaacgt
     1921 cgatgttcaa gttgtaagca acttctacag ttgcgtcaaa ttttgcaaag ttagtttctt
     1981 ttgcaagtgc tacagcttct tctacactgt atgcttttgt gctgtcgatt ttctcaagag
     2041 caacacgaag ttgtttgctt tttttagcca ttttctattc tccttgtaag tggttcaatc
     2101 gattttcatc tcccacgtca cttctcgaaa tgatgaagtc ttgcgggttt tcagtctact
     2161 atttttctct tcctacggcc ttaagctccc ttgctgtacc caagtacaag gctcagtcac
     2221 ttgcctagta tgaaaagcaa ctaatagact gctgtgagat tttctactgt gttattgatt
     2281 agtcaacaac agtgaatccc atagaacgag cagtaccttc gatcatacgc attgcagact
     2341 ctacgtttgc tgcgttcaaa tctggcatct tagtttctgc aatttcttgt acttgtgcac
     2401 gagtaactgt agcaacttta gttttattag gtgtacctga tcctttttca acacctgcag
     2461 cttttttcaa aagaacagca gctggtggtg ttttcgtaac gaaagtaaat gatttatctt
     2521 cgtaaactga gataacaact ggaatgatca taccagcttg gtcagctgta cgagcgttga
     2581 actcttttgt gaatcccatg atgttgatac cagcttgacc aagagcaggt ccaaccggtg
     2641 gagctggtgt agctttacca gcagggattt gcaattttac aagtttttcg acttttttag
     2701 ccatttttaa atcctccttt gtggttttgg cggtaattag agatttttac ctcccacaag
     2761 tatgtttttc acatacccat ccattataca ctatttatct ggaattgcaa gagaaaagtt
     2821 tattttttgt actcaatgaa aatcaaagag caaactagga agctagccgc aggctgctca
     2881 aagtacagct ttgaggttgc agataaaact gacgaagtca gctcaaaaca ctgttttgag
     2941 gttgtgaata gaaccgacgt agtcagtagg taaggcgacg ctgacgtggt ttgaagagat
     3001 tttcgaagag tattaatcga cgtagtctcc gccttcaaag ccatagtatt cttccaaact
     3061 gagaccactt gcagcaattt ctttagcttc ttttcctaca taacgcaggt gccattcctc
     3121 agccatatag cctgtttcct tttccttgcc tttgagataa cggacaacaa agccataatc
     3181 agctgcatga tccaagagcc attgggctgc tttttcttct gtcaccaaat caccatcagt
     3241 cccaatcaca tcaaaggcca agcctgtctg gtgttcgcta tagccaggac gggcagagta
     3301 acggtcagct gctgcctttc catcttggtt gacataatct tgatagagct tggtctgagt
     3361 ttcataactt ctaaaaccac tgtagtgatc gctgattggg tagtcagctg cttgcattgc
     3421 tgcaatgagt ttcagcaact ctgccttggc tgttggattt tctcctggat tgtagtcttt
     3481 tgacaaagga taacgtttat tagctaggat aatttcatcg tatttccctt gaatactata
     3541 atagctccct ttattgctaa cttctgcctt tttctgacta gaagcttgag atttgctgcc
     3601 tacagttcct tccggttgac tgctttgctc cgtcttttga gtattttctt caactttcgt
     3661 tttttcttgc gaacaagctg caagagtcaa tgctagtaaa ccagataaaa tgacatatct
     3721 ttttttcatt tctttcttcc tctctcttag gccaaatgct tctccaattc atgagataag
     3781 attttaatca tctcttcccg ctctggcgat tgcacttggc aatcttctgc tgccatttct
     3841 tcccagggca cccaccagac tgggccacgg ccattaagtc cgtgcccttt catattacct
     3901 gctcttcgcg gaaaaagatg ccaatgagcg tgggcatcgc catttcctag gagttcaata
     3961 ttcatctttt cagcctcaaa tgctttggcg actgcttctt ggaccaaact catttcctct
     4021 aaaaagcgaa gttttacaga attctccatt tggtggagtt ctgtaacatg ttcttttgct
     4081 aaaaataagg tatagccctt aaagtattgg tggtctccaa taactacata gcccgtttct
     4141 agttctttga caaagtaggg attttctcca gctttgatga gttcaattct ttgacagatt
     4201 aagcacattc tatgataccg cctcactctt gagataggca tctaccatac gctctgttgc
     4261 gaccaccgag tcaatatgag tacgctcata agaatgacta gactcgatac ccgcaccaag
     4321 aagagcgtgt ttaacttctg cacctgcaga catagccgct gaagcgtccg aaccataaaa
     4381 tggatagata tccagcttga atggaatatc ttggttttta gccaaggtca ccaaatgttg
     4441 acggaagtca tagtgataag gacctgaagc atccttgaca cagatggaca ctgtgtactc
     4501 atctgtttgc tgatcatccc ccatagctcc catatccaca gccagatatt cgactacttg
     4561 agcaggaata ttagaattag caccatgtcc tacttcttca aaaactgaaa aagcaaaatg
     4621 agttgttact ggcaattcaa tcttctcttt cttataaata cgaagcaggt tgagcaaaat
     4681 cgctgcgctg accttatcat ccaaatgacg agacttgata aaacctgtat cagtcacaac
     4741 agttcgtgga tcgaagctga taaaatcacc gacctcaatc ccaagagcac gagtttcttt
     4801 ttcattgctt acttttacat ccaaacgcac ttccatattg tcctgcgtgc gctctgcagt
     4861 tcctgcatcc ttgtagacat ggcaagaagt ttggtggatg aggatggttc ctgatacctt
     4921 ttgacctgtg ctagccacat gaacggtaca gttttcacct tcaatcatgt tccaaggaaa
     4981 accaccgata cggtccaatt taagacgacc atctggtttg acagcacgaa caatagcacc
     5041 cagcgtatcc acatgagcag tcacatagcg atgttgctca tcattttgac ctttgatggt
     5101 cacattgaca ccacccttag ctgtgcgaac tggctggtaa ccaaaacctt ctagagtctt
     5161 gactaaataa ttcgaaattt cacgagtaaa gcccgttggc gatgcgatgg ctgtcagttc
     5221 tttgatatat tctactgttt gattcatttc ttcacctctt tcgctaccta ttataacaca
     5281 tttatcatcg gataaaaaaa gaaaatcact cctgtagact tggctacaaa agtgatttaa
     5341 gtgattattc catttcaaaa acatcgcttt cttgcttgtt tggtagaacc aatgagagca
     5401 agattccaac aatggctggc accaaccatg ggagagatgc cttggcaaaa ggaagaacgc
     5461 taacaagatt tgcaagaaac tcaaccttaa acgagcttcc tagtacgctt gcaatggcaa
     5521 taactgtaac cacagcaatt gtcaactgca tacctggttt tgaaagggca acaaatttgt
     5581 tgacaatgac aatcataacg atagcaatcg tgattgggta caagataacc agtactggaa
     5641 ttgagtactt gataatcgca tcaagaccca aattggcaat agcaaatcca atcaaggtaa
     5701 aggctgtcgc ataaaccttg tagctgattt gtgggaagcg ctcattaaag aactcagctg
     5761 ttgacacaat caaaccaaca gtcgttgtga agcaggttac ggtaaccata gctgcaagga
     5821 agagttgagc tgttgagcca aagatttctt gagtggcttg tgacaagatg taaacacctg
     5881 gtgttccacc cttcatcgct tcagctggta ctgggaaatg atttccaaga aaacctaaac
     5941 cgatgtaaag agcgctgaag gcaagggcaa caacgatacc aacaacccaa atagttgaaa
     6001 tgtattcttt cttacttgaa aatccaagtt gtttcaaggt ttgaactgcg attacactaa
     6061 aggccactga ggcaagggcg tccaaggtat tataaccttc taggaaacct gtaccaaagg
     6121 cagaagcttg ataagcagct gaagcagctt gaggacttgt tccaccatat ttgatagctc
     6181 ccagaacgac caagataaca atcaaaattg caaagactgg cgttaaaata cgtccaatgc
     6241 ggtctaagat ttttgatgga ttaagcgaaa tcaaataggc tgccgcaaaa tacagaaccg
     6301 taaatacaat caagccaagt cctttatttg catccgacaa aagggggcta atccctactt
     6361 cgtaagctgt tgtagcagta cgtggggtag caaagaatgg accgattgac aagtaaagaa
     6421 ctgagaggta aagagtcgca aaccaaggcg ctatcttcgt tgaaatctcg tagatatacc
     6481 ctttaggatt tagcgttcca ataataaggg tcaagacggc gataccaacg cctgaaaaga
     6541 caaaacctgc gatggcagga agaaaatgtt ctccagatag agcacctaga gaaggcggaa
     6601 aaatcaagtt ccccgcacca aaaaatattc caaacaggag caaacctgtt agggtacctt
     6661 ttttagccat aaaaatctcc ttcatattta taaaatactg acctagtata ccacgattag
     6721 gagtctgaaa aaagcatcac gaggcaaata ttaaatgttt tcaattttct taaaaataag
     6781 aattatctaa aaataaaact ctcctaccca gtccacacca agtaggagaa atgcaaaatt
     6841 ttaaagttct tcaaaggcta acatgccacc ctggacattg ataacattat aaccttgttc
     6901 taatagaatt ggcaagcacg cgccgatctc attccagatt tgcaaataat ataatgcaag
     6961 cgatctttgt ccaattaatc ataactatca gccaattgac taagcggtag gttgtgggca
     7021 ccttctaaat gaagagctgc aaactcatcc acttctctca catccactag agaaagctgg
     7081 tcgttttggt aaagctggta aaatgcgtca aaggctattt ctttcattct ttttcttcta
     7141 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtgcg tatgttaccg
     7201 acttcgtcag ttttatctgc aacctcaaag ctgtactttg agcagcctac gactagcttc
     7261 ctagtttgct ctttgatttt cattgactat aaaatggttt taattctttt tttcaaatct
     7321 ggcactactt ctgcctcaaa ccaaggattt ttggccatcc agatttgatt tcgtggtgat
     7381 gggtgaacta gcggaaaata ggctggcaga tagtctttat agtgtttcac cctctccgtt
     7441 accttcccac tgattttctc ctgtaaatag taggcttggg catattgccc aatcaagagg
     7501 gttaactgaa tatcaggcaa ttcctgtaag agctgcggat gccatttttc tgcaaaacct
     7561 gtacgaggcg gaagatcacc cgacttgcca tgtcctggaa agtagaaatc cataggcaaa
     7621 acagcaaaat aacctgaatt gtaaaaggta tcttcatcca cacctagcca gtcccgcaag
     7681 cggtcaccac ttttatcttt ccagtaaagg cctgcttctt gagttttaag tcccggagcc
     7741 tgaccgatga tattgatgcg agcagttttt ggcgctgcaa agagaggctc aatgccacgc
     7801 tctgtatagc tggcattctg tgaatccgcc atgatagcct gtttgattct ttcgatttga
     7861 gacatctact ttccctccaa aaagaagtcc aagcataaga tctcagactt ctatcgtttt
     7921 atttgatcaa ttcgtaaata gcttcggcat aaattgctgc tgctcggaaa agatcatcca
     7981 aggcgataaa ttcattggct tggtgcatgg tatcaatcga gtctgggaac atagcaccgt
     8041 aggcaactcc gcgttctagc aagcgaccaa aggttccacc accgatgact tgttcatgac
     8101 ctttaaggcc agtttgtttt tcatagatat tcaacaaggt ttgcacaagt ggatcttcca
     8161 ttggcacata gtgaggcgtg tgaccgtgtt cagacaggct aacagaaaca actggcaagt
     8221 tttcaaggat tgacttgatt tgttctggac ttgttccttt tggatagcgg atgttgaggg
     8281 caatggtatt atcagcactt gtttcatcga agcggaaaac gccggcattc atagaaagag
     8341 cacccatctt ttcatccaca tgagcaatct taagattttc accctcatga tcgttcaaga
     8401 gaattttacc tgcgatgtca aggtagtctt tggctggacc agcaaagcca aactggctga
     8461 ggaagagggc aaggtaagtt gcgccattga cacctgaagc aggcatagca ccgtgggctg
     8521 atttaccaat gatcgtcacc ttgtatttgc cagcttcttc ttggagttct cctctaagtt
     8581 tgtgttctgc aacaaaggca tctagtttag cttgcaagtc agccaagtca cctgaaacga
     8641 ctgctgttgc tgattctggt accatatttt cacgtaaacc acctgtaaag ctgtgaagac
     8701 gggcaacacc tgtattttct cctgcaaagt ggaggtattc cgtgatattt cctttttcac
     8761 cattgatgat tggaaattca gcatctggtg agaaaccgaa atctggtttg gcaagtccta
     8821 cgtgctcaaa gtagtagtcc atgtctgccc agcctgattc ttcgtctgtt ccaacgatga
     8881 agcgaacttt cttagaagtt ggaagaccca attctttgat gattttcaaa ccatagtaac
     8941 aagctgttgt aggaccctta tcgtccgaag ccccgcgcgc ataaaggcga ccatctttga
     9001 tagttggtgt gtaagggtct gtgtcccaac cgctaccagc aggcaccaca tccatatggg
     9061 caaagattcc gagaacttct tctccatcac caaactcaaa atgtcctgca tagttatcaa
     9121 cattcttagt tgggtagcca tcgcggtctg cgatttcaag gaatttctcc aaggctttta
     9181 ctggaccagg cccaaatgga tgctgggcat cagccttgct gtcatcacgt tctgaattga
     9241 tttccaaaag gctaaacaag tcagccaaga ggtcttcttt gcgtttttct acttctgctg
     9301 taaaatcaat tgctgtcatt ttttcttctt tctatctttt ctcgatgatt tcatctactg
     9361 gcaagcggta gcttggttcc aatttttcgt ctgtataacc cactgtgatc aagagttctg
     9421 ggcggaaacg gtcttcgatt tccaaaactt cattaacttt tgatttgtca aaaccaagaa
     9481 taatgttaga accaattcct tggtctgtca atgcaagaac caagttcatg gcaaccaaac
     9541 ctgcattgag agctaggtag tcgctgactt gttgctcact gtaacgggca aactcagctg
     9601 gcagattttt cataaaatat tgaagttgct cttcagaaaa gttattagca ccaccaacac
     9661 gggcaatctt acgagcacgt ttggctaagt ccgtatctgt aaacaaggca atggttacag
     9721 gcgctgatga tacctgttca aaattggaac cataagctaa ctttgccagt tcagcatttt
     9781 tctcacgtac caccacaaat ttccaaggct ggctgttgtg ggcgcttggc gccaaggttg
     9841 caatttcgat agccgtacgc acatctttgg gatcaacagg cttatcagta aaatgcttag
     9901 tcgcatgacg ttttttattt aattcaagaa atttcataat cgatttcctt ttctaattct
     9961 actgcttcca ttctaccata atttgaaaga gcttgcaggg atttttcatg attaagtttt
    10021 tctatcacag acataaaaga tatatattgg tttatcagga aagtttctga taaactagca
    10081 agtactttac atttgaatgg agacagtatg aaaaaattta gcctattact agctatccta
    10141 ccatttttgg ttgcctgtgg gaatcaagct acacccaaag agactagcgc tcaaaagaca
    10201 atcgtccttg ctacagctgg cgacgtgcca ccatttgact acgaagacaa gggcaatctg
    10261 acaggcttcg atatcgaagt tttaaaggca gtagatgaaa aactcagcga ctacgagatt
    10321 caattccaaa gaaccgcctg ggagagcatc ttcccaggac ttgattctgg tcactatcag
    10381 gctgcggcca ataacttgag ttacacaaaa gagcgcgctg aaaaatacct ttactcgctt
    10441 ccaatttcca acaatcccct cgtccttgtc agcaacaaga aaaatccttt gacttctctt
    10501 gaccagatcg ctggtaaaac aacacaagag gataccggaa cttctaacgc tcaattcatc
    10561 aataactgga atcagaaaca cactgataat cccgctacaa ttaatttttc tggtgaggat
    10621 attggtaaac gaatcctaga ccttgctaac ggagagtttg atttcctagt ttttgacaag
    10681 gtatccgttc aaaagattat caaggaccgt ggtttagacc tctcagtcgt tgatttacct
    10741 tctgcagata gccccagcaa ctatatcgtt ttctcaagcg accaaaaaga gtttaaagag
    10801 caatttgata aagcgctcaa agaactctat caagacggaa cccttgaaaa actcagcaat
    10861 acctatctag gtggttctta cctcccagat caatctcagt tacaataaca ctcttcgaaa
    10921 atctcttcaa accacgtcag ctttatctgc aacctcaaag ctgtgctttg agcaacctac
    10981 ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatatact aaaagcgatt
    11041 ggaccagcca atcgcttttt tagtttgcat tggctatttt aggaaactct tacaaaaaat
    11101 caaaaaaatc cttcacatcc tctacatacc catgcttttc tattaagctg gctaataatt
    11161 ccagattgtg cccctgatag ttatcttcac gacgcagttc ttcatacatt tcgataaagg
    11221 gaagcccctt ggacttggcc aattctaact cagcttcgta atcataagca actttacgaa
    11281 attggatatt gagtaattct ccatcttcaa cttctatcac ggcatactgg gcacggtgat
    11341 tttttaacgc ctcccaatta aaatagggca tgccaatcga ccctggattg atgatttgtt
    11401 gcccttgact tccataacga agcaactgct tgtgaacatg accataaact gccacgtccg
    11461 tttccgcatc tagtagttgg tcaaatttct ctgtatcatt ctcaactagc aagtcaccac
    11521 catagttttt gtcaggtaaa ttatgagaga tagaaaagcg caatccgtca atttctttct
    11581 tttccagcaa aggcaagctt cgtagccaga caatcgttgc aggatccatt cgctccatca
    11641 aatactgtgt catacgcaag agctgaactt cctgtgggtc ttctaagcca tattgcccat
    11701 ctaaagcctc aaggacacaa tcatcccaat tgcctcgaac acttgccgtg ataggaagtt
    11761 cctttaacag agcgaccaag tcatttgcac ctggaccagg gaggaaaatg tctcccatga
    11821 gccaatattc actggctcct tgagttttag catctgcaat cactgcttct agcgccgtcg
    11881 cattgccatg aatatctgat aaaattgcga ttttatggtt tattgtggtt tccttccgtt
    11941 tggtaatcta ctctttcttc cgccacttga agcaagattt ctgtttcctg cgggttcaac
    12001 ttggtttgca cagcctctgc tactgctctt ggtactccaa cttcgacaat ctcatccaca
    12061 ctggcttcct tgattttggt cagagacttg aagtgcctca tgagattttg cttgcgttta
    12121 ggtcccagac catcaatccc atccaattga gatgagaaag aatttttgga gcgcagttgg
    12181 cggtggaagg taatggcaaa gcggtggacc tcatcttgga tgcgttggag gaggaaaaat
    12241 tcctgagaat tgcgagacaa gtccaccact tccagcggat ctccaaagag caattcatgg
    12301 gtttggtgct tatcattctt ttgcagacct gcaattggaa tatccaagcc cagttcttct
    12361 tggatgactt gcttagcaat attgacttga ccttgccccc catcaatcac aatcaaatct
    12421 ggaggagtca aagcctcacg ctgtactcga ccatagcgtc tgcgaatgac ctctctcatg
    12481 ctggcatagt cgtctggtcc aacaaccgtt tttatcttgt acttacggta atccttctta
    12541 ctcggtttac cgttgacaaa gaccaccata gccgaaacag ggctagttcc catgatatta
    12601 gagttatcga aggactcgat acgtactggg gtcgggattt ggagcaaacg tcctagattt
    12661 tcaatagctc cttgggtctt ctcgacagat ttctctagca ggttaaattt ctgctccaga
    12721 ctaacacgtg cattttttat ggctagattg accagctgtt ttttctctcc acgttggggt
    12781 ttgagaatct tggtatccac caaagccttg acagcttctt cgtcaatatc ctgcggaatc
    12841 agtacctcat tgggaactag gtgagatttt tcttgataga attgtcctac ataggtcaaa
    12901 aaatcctcat ctggatcatt gaagtagggg aagagattga catcgcgctc gatgagctta
    12961 ccctgacgga caaagaaaac ctgcacacac atccagccct tatccacata gtagccaaag
    13021 acatcgcgat tttggagatc cttagccatg acccgttgct tggttcgaag cgttccaata
    13081 gcctgaatca ggtcacggta ttccgccgca cgttcaaact ccatagtctg ggctgccgct
    13141 gccattttgc cctttagctc atcaatgatt ttgttatcct gccctttcag aaaatcagaa
    13201 acctcctggg ccatagactt gaaataagtc tcatccttct tacagatggt gtgggccatg
    13261 cattgaccga tatggtaata aaaacagacc ttagagggcg ggttggtaca cttacgaaaa
    13321 gggaatatcc gatccagcaa ccgcttgatt tcattggctg cccccacatc gggatagggt
    13381 ccaaaataaa gacctccgtc ctttttgacc tgacgagtga taatcaagcg tggatagcgc
    13441 tcattggtga ttttgatgaa aggataggac ttgtcatcct tgagcatgat attgtacttg
    13501 ggcttgtttt ccttgatcag gttgatttct aggagaagtg cctcaatatt agactccgta
    13561 acaataaatt caaaatccac aatttcagac accagagcct ctgtcttggt atcatgactt
    13621 ccacgaaaat aggaccgtac tcgattacgc agatttttag cctttcctac atagataatg
    13681 gtgccatttt tatccttatg aatgtagcaa ccagggctgg tcggcaagag ctctagtttt
    13741 gatttaatca agttgttcat agttccatta tagcaaaaaa agtagggaaa gatagtaccc
    13801 tactcactag tctcatatat ttttcggagg tttgcaacat cctcttcctg gataccataa
    13861 aaggaacctg ctggttgcat gacagacttc tcatctgtat ggtccaagcc aatcgcatga
    13921 cctaactcat gttctgccgt atggacaagg cgttcatagg agtagccata gtatggattg
    13981 gacaaataat aatgattcaa ccgcaccgtt acggacaaga attgccctgt taagagatta
    14041 gtttgacttt ccgcctctcc tgccacagga gtgcctccgt cgttcatctc cgtagccgta
    14101 atatccgcct tactagactc agtcacgagt tcaaagttaa aagcaccagt ttgattccag
    14161 ttctggattg cttctaaata agcctcttga aagcgtgaat ccatctgcgg atccaggtaa
    14221 atacgagcag aggcctgtgc ccaccttcct tcagaatgct ggtgactatc tgtctggctt
    14281 aacttaggca gttgccctgt tttctcccat tggtcaatac tttgttgacc aatttttact
    14341 gaccgttctg cttgctttag cgctccttga aaatccccgt tcagatacca gagaagtccg
    14401 aaagcaagca cacataagag cacaactatc caaaccagac gccaaaacaa acgccacaca
    14461 aaagaaaaga aagcccctat caaacgaaaa agccagcgca tgtctctcca cctttctagc
    14521 aaataagaat tattttacta aaagaagcta aaagaaatct aaatactgac tttttcatct
    14581 taacgtccta ctattttttt gagtaactgg atagctttgt attttaaagg cgatggatgg
    14641 taacggaaag tacccgcttt gcgtacaata tagccattaa aattctgttt aaaacgcaaa
    14701 acaccatcac ttccatcaaa aatcccttga atgcctagga agttgtattt aggtattcca
    14761 cgttttatgc tttccaacat aacatatttt tgaagcaggg caggggcata gaacttatta
    14821 aactcagtgt aggaaccact aaagagataa gtcgtttcct gaggcatata aacaaataaa
    14881 ctcccagcta aaacaatatc ttcttctcca tatttttcaa tcaagtctcg cgcttctgct
    14941 tttcgaactt caaacgtttc aaattgacta gaatattctc tcagttgatt ttgttttttc
    15001 tcagaatgag gatttttact caaatcaagt cgcaacttgt ccaagttttc ttctagttta
    15061 ctttgttcac cttgcaattt gctcatatag tccgaaaaat ttaagcttgc tatgagaaac
    15121 tccgcttgtt ctccaaaagt atcataaaaa tgctcataat attctaaact tttatcacta
    15181 tattctctac gttcagaggt ttcttttgtt atattcttaa aaatcgatag ttcttcacgt
    15241 tttaactttt tcaaccgaat gccaaaggtt tcagcctttt tcaccaaggg tttacccttt
    15301 ttgctaaaac ttttaagcaa actcttttca gttaattcag ttaaatcttt atagtataac
    15361 caatctggtt ctccacctgg gtaacctgtt gttaagccat caaattgata acctaaatca
    15421 gtcaaacctt gaataatact ttttttctca gcatctattg agttaccttg gctatcaaaa
    15481 gtttgataag tttcataagg ttttacaagc aactctaata caccattttg cttggcatat
    15541 tcttttaact ctgcataaaa aactggaaga gcatcttgtt gggtataaat cggccccgaa
    15601 ttgagttcca tatgcagacc acccagcatg ggcaagctat aaaccagagc tgcaacttga
    15661 atttctcctt cttgtttcaa agcaagataa acaattcgag cccctctttt ttctagcaaa
    15721 tcccccatct ggacagattg cataaaggaa cgagaagaaa cctgatcaga ataagtctga
    15781 aactcttctt tcgtgagtgt tgttagtgcc atatacttac tttctatgtt tttttcttaa
    15841 tgttttacgg aaatcaagag caagtcttaa cagaggatag agaggatgag tgggcattgt
    15901 aaattcaccc aagtattctt caatcgttgg attaaatttt tccttaaaat gataaagtcc
    15961 accattgaga gagttttcaa caccacctaa attttgccaa accatacctc gctcaaaggc
    16021 atagcgagcc gtttcatacc atgttaaaat tggtgcattg taacgtttaa aatcatcatc
    16081 cataccagca tatatattga cagaggtagt accaaattcc aaactcaaag tagccgctaa
    16141 aggaactctc gcttgaccta catctatata ttcctgcaag aaggtcaatt cctctaacaa
    16201 acgttctttt tccttcttct gcgcttctac ttttgaaatt cgagtcgact cagtaaacgt
    16261 ctcttccaag gctctatttt tcgctaactg ttcttctaat tcttgcgaac gtttagaaac
    16321 atccaaggtg gccaaggtga tataggcctt gtccttaaaa ttatctaaca attttttata
    16381 ataggcttca ttcctcaaat gaatctcttt tcgcttctca gtttttttca tcaactccga
    16441 aaatgaatct aatagttcca gtccaccata ttgaatctca agccctttgt ttcgtgctgt
    16501 tcgaatagcc tgttttgttg acttggaaag tttatcttct tcaaaatttt ccttgtatat
    16561 tttcgcctga atacgaggtt gaatggtgtc tcccatttcc tccgtttttc ctgaccacct
    16621 tactcccatt tgttgcaaac tatcaataat agccagattt tcaggaaatt ctgtcttttc
    16681 ctgattgatt aaactttgag ataggcaaat acttgggtca aaagtcacaa aaaccgctct
    16741 cttactgcga gcataggact taatagactg aatgacaaaa ttcaagagtt ctttatcccc
    16801 ataatccaat ataggtcctc ttgggatgta aaacatttta tagcctagcg gaagagttct
    16861 aatcaaaata ctagctgtcg ccagtaattt ttcttccctg taaacaccaa acttctcatg
    16921 ttgccaatta gacttaactt cctcccaagc actactttgt aatacattgg ctaattcatg
    16981 ttctttgaca aactgatcat attctaatgt gggaatgcca atttgataac ggtacatttc
    17041 ctactctctt tcctccagta ttttattact attctactac tttcgtttga aaagtctagt
    17101 gaaaacatat tttattttag ttctactccc cctatgctga agttcaaact aagtcagtct
    17161 ctcttctaat ttgaaatcaa ttggtagggt tgttaaaaaa acttccaatt gtttttccca
    17221 gtagtaccac tcgtgagttc cagcgctatg gctataggtc acatcaaaac ctagtttttt
    17281 gagatttttc actgcgagat tattggcttc gtacaagaaa tcctgttcgc cacaccacgc
    17341 ccaaagtttg gtctttttat ccgatttttt agccagactt tcaagagaat agggactagt
    17401 tgtccagtct ctaatctctc caaaaacacc tctccagtag gctggacttc ccagattttg
    17461 actttcagga gaaaagtttt gaaagctgag ggcacctgaa aaactagctg catgagaaaa
    17521 acgatttgtc gcaagagcct gtttgaagca gccgtaacct cccatagaaa gaccagcgat
    17581 aaaggtcttt tcacgcttgc tagtcatatt agggaagaag cgtttcagaa cctgtggcaa
    17641 ttcctctgct agagccgtgt agtagtcaaa accatactgg gtatcggtgt accaaccatt
    17701 gctggtattg ggcataacaa cgatgagatt agttcctcga agcaagcgtt ctacattggt
    17761 ccgcttaagc caactattat gatttccaga catcccgtgc aaaaggtaca agacgggaat
    17821 atcttcacac tctggttctt ccactcgatt ggcatcaggg tagaggacat tcacccccca
    17881 ctccatatcc aatacttgtg agtaatactc gattttcatt actgccatga ttttctcctt
    17941 ctatttttct ataagaaaaa gccgaaactc gactttctct ctgtttattt caacgattat
    18001 tttgcttcca tgactactgg taaaatagct ggacgacgct tggtttggtc aaagagatac
    18061 ttggtcaaat tatctcgaac cttcccttta agatctgccc agtcaaagtc atctccttga
    18121 agataatctt ctaccgtttg gttaatcaat tctgaacttt cacggagaat atcgcgactc
    18181 ttcttgagat aaacaaatcc acgcgtgtga acacgagccc tagccacaat tttcttctca
    18241 cgacggttga ctgtaatagc cacgatgaaa attccatcct ctgacaagac cttacggtca
    18301 cgaagaacaa catttccaac atcaccaatg gcattcccat caattaagat atctcctgct
    18361 gaaaccgatc cagctggaac aaagtctcca ttctcgtaag ccatggtcgt ccccttttta
    18421 ggaatgaaga tgcgttctgg caacatccca actgccatgg cagccttagc gtgagcatcc
    18481 aactcacgat actccccttg gacagggaag aggtacttag gttgcaaaag attgatcatc
    18541 agctgcaaat cacgcacatt tccgtgccct gatacatgta aactttgggt aatcaatttg
    18601 acaaccccac ctgcctgata aatcatattt tccacacgcg caacaaaggc ttctttagca
    18661 atagacggag ccgtagcaat atagaccagg tccccatcct tgatttctac ataacgatgg
    18721 cgaccaatcg acatcttacg aagtccattg ataggttcac ccatacgacc tgtctcaaga
    18781 ataatcaact catggtcttc aaagcgagac atatctttag gcttaatcaa gagaatttcg
    18841 ttggctaaag acaacttctt aagacgaatc gctgtgcgga cgatattttc aatatcaaat
    18901 cctgtcaaga cgatacgtcg acctgtttta tccgcagcgt caaaaatctg ctgaatacga
    18961 gaaagattac tggaaacagc tgcaacgatg atacgacctt cccagtcagc aatagtttgg
    19021 gtaatttcat ccctaacttc actttcacta gccacctgaa tattgctgtc tgcattggcc
    19081 gaatcactga ggagagccag gacgccgtca cgaccaatct ctgccaaacg agcaaaatca
    19141 gttgcataag attcactagc cgtttggtca aatttgaagt cacctgtata aacgatgctt
    19201 ccctccgatg tcttcaagac aattcccaga ctctctggaa cggagtaagt cgtagggaag
    19261 aaggaaacca ctgtcccacc aaaatcaatc tccgtattct catcaatgac atggaaatca
    19321 ttaaatttct taacggcatc atttcctttg acaaagagct ttgccaactc aatggtcaac
    19381 tcagacccaa atacaggaac tttagcctct gccaagagat aaggtagagc accaatggca
    19441 tccgcatgcc cgtgggtcaa gaaaacccca gcaatacggt cgctattttc aaaaaggtaa
    19501 tccatgtttg gaatcaccac atcgacccct aattgttcat tttcaggata ttttaaccct
    19561 acattcaaaa caaaaatgga ctctccaatt tcagcaatgt acatattttt tccattctca
    19621 cgcacaccac caagtgttgt taaactgata ttactcattt ttcctccaaa atcttagttt
    19681 atcttgatta tagggcaact ctaccctctt attctaaaag ttctaacact ttcagccgaa
    19741 tcttttccta ccattatacc atttttttga tgattttcaa aatgaaggtc tgttttcaaa
    19801 aaagagttga tttcccaact ctttcctaac ttctactctt tttccatcaa aaaatcataa
    19861 atttcttgca ccgtacccag cgccatcatt tcttggtctt taacggtttg tttgagattt
    19921 tggtaaattt gactttctcc tatctcccgc tttggcgcct ctttattgac tgtcatcaca
    19981 ccatctttta tcgtcacaaa gcctagttct tcaaatactt gaatcatctt gaccagcaag
    20041 atttgttgaa tattaagata tgcagccaaa tctttcagct tgtagcgaat atcaaactct
    20101 gggaactggt aaatagtctt gtacaatttg gcaaactgat ctctagtccc ataacctgtc
    20161 agataatagg ccttgtcaat atcatttttg aaatagacag cagagaaatg ctgttcctga
    20221 aaaatggtct tcagctgagt aatatcctct ggaatgtttt ttacgacaac agcttcacta
    20281 gccgcaagat ttggcagttc tccaggaaaa tccaagactg gaacaccttc tggcaagact
    20341 gcattttttc cacgaatgtt aaaaagttga acaccttcca ctcgcgcatc caccatcatc
    20401 aactggaggg cagtttggcc attccattgg ttgacagaca atttaaccgc taactctaga
    20461 ttcttggttt gagaaaactc tgtcgcccat ctgccttgac caaaggctac cacttcaaaa
    20521 ctcgcctcac ccttggaaat tttcagcttt agatgggcat tacctgcccc catagtacga
    20581 gcactttcga cctgaaaatt cttgatataa aaaataggtt tctgattatc cattccaaaa
    20641 ggagctaaac gttcaaaact tttgaccgtt tccaagctaa gtgcctccaa atccaactct
    20701 tcatctaggt ttaacttatt cttgccacca gcatctgcac ctttttcacg aacataatct
    20761 tccaaaacct gagataaatc tgagagttgc tcaacttcca gcgtcatacc cgctgcacct
    20821 gcatgacctc caaaggcgat gaagaggtct cgatggggat ccagagcttc aaaaatatcg
    20881 accgcttcca cactacgagc actgcccttg gcacgaccgt cttctatatt aagaacaatg
    20941 actgtctgtc ccaattcttc caataaacga ccagccacga ttcctagaac cccaggattc
    21001 cagccttcct tggccaagac ctgaaccttc ttctcaggat ccaccatggt cttggcttct
    21061 tcatagatag actgaacgat ttccttgcgc tcttcgtttt tctggtgaat cataagggca
    21121 atctcatgcg cttcctcatc atcaaatcca gtcaacaaat caatggcagg attgggatca
    21181 tccaagcggc ccaaggcatt caaacgagga gcaatctgga aaccaaccgt ttcttctgtt
    21241 acttcgttgg cagcaatccc agccatgtcc agcatttctt gcagaccaat gcgctgggta
    21301 tgacccaaca tttccagacc atattgaact aagatacgat tttcatccgt cagactcacc
    21361 atatctgcaa tagttccaat agcgaccaaa tcaagcaatt ccacttgcac ttcttctaac
    21421 agggcacaag ccaacttgaa agcaactcca caaccagcca aatatttaaa aggataatcc
    21481 gcatctggat gttcaggatg gacaatagca taagcatctg gcagggtttc aggcatggaa
    21541 tgatggtctg tcacaatgac atctactccc atagactgag ccaatgcaat agcctcatga
    21601 ccagcaaccc cattgtccac cgtcacaatc aaggaaatcc cttcttgctc gataaagtat
    21661 ttataaacac tagcattagg gccatagcca tcggtaaaac gatttggcag gtaaactcgg
    21721 cactcagcac caagttgttc caaactttcc ttcacaatag aagccgaagt catgccatcc
    21781 gcatcatagt ctccataaac aagaatattt tccccttctt caatagcctg acgaatccgc
    21841 tccactgcct tgtccatatc atggagcaga taagcatcat gtaagtcctc caaggaaggt
    21901 tctaaaaact tcttcagact ttcttggtcc tgaatccctc tctcaaacaa taaccgagcc
    21961 acctcaggac ccagtccagc cttcttggct atctttgtaa aatccgcatc ttctacctgc
    22021 agggcaaact gccattcata agtaggtgtt atcaaaaaga catccactct ttctaagaat
    22081 tctattgctt cattataaca tgatttagac gttttctcta tccagattgc ttttttataa
    22141 cattttatag tatattgaaa ctagaatagt acacctctac ttctaaaata ttgttagaaa
    22201 tcgatttgac tgtcccgatc gatttgtcct gttcttattt cactatagtg aattttttca
    22261 gatatggttt gacaagaaca ttcttttatt gtagaatcgt gttataaaat ctaacataaa
    22321 tgagatctcc catggcttta gtagaattta aaaacgtcga aaaatattac ggagactacc
    22381 acgcactccg caacatcaat ctccgttttg aaaaaggaca agttgttgtc ctgcttggac
    22441 cttctggctc tgggaagtcc actcttatcc gtacgctcaa tggtttagag gctgttgaca
    22501 aaggaagtct cctagtcaat gggcaccaag ttgctggtgc cagccagaaa gatttggtac
    22561 ctcttcgcaa ggaagtcggc atggtttttc aacattttaa cctttatcca cacaaaacgg
    22621 tgttagaaaa cgtgacactt gcacccatta aagttctagg aattgataaa aaagaagctg
    22681 aaaaaaccgc ccaaaaatat ctggaatttg taaatatgtg ggacaagaaa gattcctatc
    22741 ccgccatact atctggtgga caaaaacagc ggatcgccat cgctcgtggt cttgctatgc
    22801 atccggaact cctcctcttt gatgaaccaa catctgctct tgatcctgag actatcggag
    22861 atgttctagc agttatgcag aaactggcgc atgatgggat gaacatgatc atcgttaccc
    22921 acgaaatggg ctttgctcga gaggttgcgg accgcattat ctttatggcc gacggagaag
    22981 ttttagtaga tacgacagat gtcgataact tttttgacaa tccaagcaaa cctcgtgccc
    23041 aacaattcct cagcaaaatt atcaaccacg aaagtgacaa agtcaaataa ggaggcgcct
    23101 atgaaaaaaa attcttttta tcagcattat tgattagcct tttcggcctt gctgctgcca
    23161 aaccagtcca ggctgatact aatatcgcag acattcaaaa aagaggcgaa ctggttgtcg
    23221 gtgtcaaaca agacgttccc aattttggtt acaaagatcc caagaccggt acttattctg
    23281 gtatcgaaac cgacttggcc aagatggtag ctgatgaact caaggtcaag attcgctatg
    23341 tgccggttac agcacaaacc cgcggccccc ttctagacaa tgaacaggtc gatatggata
    23401 tcgcgacctt taccatcacg gacgaacgca aaaaactcta caactttacc agtccctact
    23461 acacagacgc ttctggattt ttggtcaata aatctgccaa aatcaaaaag attgaggacc
    23521 taaacggcaa aaccatcgga gtcgcccaag gttctatcac ccaacgcctg attactgaac
    23581 tgggtaaaaa gaaaggtctg aagtttaaat tcgtcgaact tggttcctac ccagaattga
    23641 ttacttccct gcacgctcat cgtatcgata ccttttccgt tgaccgctct attctatctg
    23701 gctacactag taaacggaca gcactactag atgatagttt caagccatct gactacggta
    23761 ttgttaccaa gaaatcaaat acagagctca acgactatct tgataacttg gttactaaat
    23821 ggagcaagga tggtagtttg cagaaacttt atgaccgtta caagctcaaa ccatctagcc
    23881 atactgcaga ttaaggagga caccccatga cagatttatc atcttggaca gcctattttc
    23941 aggattttgg acaatttttc aatggtttcc tcttcaccct tgccctagcg gttggttcct
    24001 ttatcctcgc tatggttttg ggcatcttct ttggtgccat gtcaaccagt aaacgtccaa
    24061 ttttacgcat tttagctcgc atctttgttg aattttacca aaatactccc ctcttggtgc
    24121 agtttgttat tgttttttat ggcctacctc ttatcagtga ccatatcatc atgattccaa
    24181 tttattggac agctgttctc tgcgtgggac tctatcacgg cgcttatatc gctgaggtta
    24241 ttcgttcagg gattcagtct attcctagtg gtcagatgga ggccgccttg tcgcaaggtt
    24301 ttacctatat cagtgccatg cgcttgatta tcttgcctca gaccttccgc atcattctcc
    24361 ctccattgac caaccaaatt gttaacctca tcaagaacac ctctactgta gctatcatct
    24421 ctggagtaga cttgatgttt gtgactaagt cttggtcggc tctcaacgga aactatatcc
    24481 cagccttttt aggtgctgct cttctctact ttgctctatg cttccctgtt gcccagtttg
    24541 gtcgcaagat ggagcaagcc aacaaaaaag cctattcact ttaggaggtt actatggaat
    24601 ctattttaga agttttaacc ccagataacc tagtctttat ctttaaagga tttggcttga
    24661 ccctctatat ttctctgatt gccatcatcc tctctactat catcggtacg gtgctagctg
    24721 tcatgagaaa tggcaaaaat cctatcttac gcattatttc cagtatttat atcgagtttg
    24781 tgcgcaacgt tcccaacctt ctctggattt ttactatctt tttggtgttc aaaatgaagt
    24841 ccacaccagc aggtattaca gcctttactc tctttacatc agcagccttg gctgagatta
    24901 ttcgaggcgg tctcaatgcc gtagacaagg gacaatacga agcaggaatg tcacaaggct
    24961 tcacctcagc ccaaatcctc tactacatca ttctcccaca agccatccgc aaaatgctac
    25021 cagccatcat ttctcagttt gttcccgtga ttaaggatac cagtctcctc tactctgtta
    25081 tcgccctaca agaactcttt ggagccagcc aaattctcat gggccgttat ttcgaaccag
    25141 agcaggtctt cagtctttac atcctgattg ccctcatcta cttcagcttt aacctagcaa
    25201 tttctagcct gtctcatatg ctagccaaac gttggcaaca agctgcagaa taatactctt
    25261 cgaaaatctc ttcaaaccac gtcagcttca ccttgccgta ctcaagtaca gcctgcggct
    25321 agcttcctag tttgctcttt gattttcatt gagtataaac agccactctc cagttcaatt
    25381 ggagagtttt ttgatgagag tagatattta tagacctcaa tttgacacca tacattttct
    25441 atgataaaat gtaacaaatt tatttacaac aaatcgaaat ctaaatgaaa tggaattttc
    25501 tatgaaatca gtcaaaggac tactctttat catagctagt tttatcttga ctcttttgac
    25561 ttggatgaac acttctcccc aattcatgat tccaggacta gctttaacaa gcctatctct
    25621 gacttttatc ctagccactc gtctcccact actagaaagc tggtttcacg gtttggagaa
    25681 ggtctacacc gtccacaaat tcacagcctt tctctccatc atcctactaa tctttcataa
    25741 ctttagtatg ggcggtttgt ggggctctcg cttagctgct cagtttggta atcttgccat
    25801 ctatatcttt gccagcatca tccttgtcgc ctatttaggc aaatacatcc aatacgaagc
    25861 ttggcgatgg attcaccgcc tggtttacct agcctatatt ttaggactct ttcacatcta
    25921 catgataatg ggcaatcgtc tccttacatt taatcttcta agttttcttg ttggtagcta
    25981 tgccctttta ggcttactag ctggttttta tatcattttt ctatatcaaa agatttcctt
    26041 cccctatcta ggaaaaatta cccatctcaa acgcttaaat cacgatacta gagaaattca
    26101 aatccatctt agcagacctt tcaactatca atcaggacaa tttgcctttc taaagatttt
    26161 ccaagaaggc tttgaaagtg ctccgcatcc cttttctatc tcaggaggtc atggtcaaac
    26221 tctttacttt actgttaaaa attcaggcga ccataccaat aatatctatg ataatcttca
    26281 agccggcagc aaagtaaccc tagacagagc ttacggacac atgatcatag aagaaggacg
    26341 agaaaatcag gtttggattg ctggaggtat tgggatcacc cccttcatct cttacatccg
    26401 tgaacatcct attttagata aacaggttca cttctactat agcttccgtg gagatgaaaa
    26461 tgcagtctac ctagatttac tccgtaacta tgctcagaaa aatcctaatt ttgaactcca
    26521 tctaatcgac agtacgaaag acggctatct taattttgaa caaaaagaag tgcccgaaca
    26581 tgcaaccgtc tatatgtgtg gtcctatttc tatgatgaag gcacttgcca aacagattaa
    26641 gaaacaaaat ccaaaaacag agcttattta cgaaggattc aagttcaaat aagtaatcat
    26701 actctcctgg aatttcccag gagagttttt tatagccaaa tgaaataaga ccggaacgat
    26761 ggaattttgg cattcaaatc aattgataag aatattttat agtggagtga aataggatac
    26821 gaacaaattg attaggaaaa tcaaatgaat ttatagaaat cttttagcag ttatgttatc
    26881 ctattctagt ttcaaaacgc tatagaagta gcattgtgct agtctagatt cagtttacta
    26941 tactaaaacg agtagcttga aatcaaaaaa cccaccctca caggcaggtt ttatctgtat
    27001 tattcagcta gattatgctt taccttctga accgaatacg tcgatacgtt cttcaaccga
    27061 tgcttggata gcttttacac cgtcagccaa gaatttacgt gggtcgaaga gttttttctt
    27121 atcgtattct gcttcgtttg cttcgtagtc acgagcaaat ttacgagttg cgttagcgaa
    27181 tgcgatttgg cattctgtgt taacgttaac tttggcaaca ccaagtttga tagctgcttg
    27241 gatttgctca tcaggaatac ctgatccacc gtgcaatacg attgggaatc ctggaagagc
    27301 ttctgtcaat ttttgcaagt ggtcaaggtc aagaccttcc cagtttactg ggtaaggacc
    27361 gtggatgtta ccgataccag ctgccaagaa gtcgatacca gtttcaacca ttgctttagc
    27421 gtcttcgatt ggagccaatt cacctttacc gatgattccg tcttcttcac caccgatagt
    27481 accaacttca gcttctactg agataccttt agcgtgtgct ttttcaacaa cttctttagc
    27541 caatttaagg ttttcttcaa ctggaaggtg tgaaccgtca aacatgattg aagtataacc
    27601 aacttcaata cactcaagtg catcttcgta gtgaccgtgg tcaaggtgga tagctactgg
    27661 tacagtgata cccattgatt caacaaggtt agcgatcaag ttgcgagcaa ctttgtaacc
    27721 acccatgtat ttagcagcac ccattgaagt ttggatcaaa actggagctt ttttagcttc
    27781 tgctgcgcgc aagatagctt gagtccactc aaggttgttt gtgttaaatc caccaactgc
    27841 ataaccgttg tcacgggctg cttggacaaa tttttctgct gaaacgattg ccattttatc
    27901 aggcctcctg tatattttta tgggtcatcc catttacatt gttcatttta tcactttttg
    27961 ccaaaaaaat ctagtttttc ccgcagtttc gattgatttt cttctaactc catctatgta
    28021 aaccctttct ctccctagtc ttgggcgact tttggaaaag ctataaagaa ggttaaacga
    28081 ttctcctcca tctcgaaacg ataagctaat ttttcatgtt ctaatagact cttaaccaca
    28141 aagagcccca taccagaccc cttgaccttg cgactagcat tgtcagaaaa agactgggct
    28201 agtttttctt gttcctctga gctacagcta ttttcgataa aaagttctcc ttctctttct
    28261 ccaattcgaa ctaagccacc tggaacagag tgcttaatgg cattgctgat gagattagaa
    28321 agaatcaact tcataactga tgggtttaga taagcctgct gatgggtcaa actattgtct
    28381 atctggagct ctctttcctt ggctagcaag gcataatctt tgaccagatt ttgcgtcatc
    28441 tggaggaggt caattgtttc cctatcatct cgcaattcct gcacagaaga gagggaaagt
    28501 atctgcagaa catggtgatt gagttcatcc acaatcccca aggcaactcc cagatactgg
    28561 tctctatcct tataacgacc gatattctct ctcatatttt cgattaggat tttcaaacta
    28621 gccagcggtg ttttcaattc atgagaagct cctcgtagga attcgacctt catcttctcc
    28681 agctggagaa tggcttcatt cttttcatgc aagtccgcaa taacagtcaa gagatgctgg
    28741 tagaggctat tgatttgttc cttgagatta cctatctcat ccttagaatc cacgcgcaat
    28801 cgcacttggg aatccaggtc catcatccga cgggtcaccc gcttaatttc caaaatcggt
    28861 gcaacaatag tccgagcgta gatgtaggcc accaagaggg aaatcagaaa ggaggccagc
    28921 aaggtatagg gaagaaactg gagactgatt tgctccgctt ccttttgtaa atccatggaa
    28981 gctagaaact ggagaatcat agtaccaccg tcttgcgttt tcacctcgcg ctcctcaata
    29041 aagagagagg ttgtctggcg gtctgtgtcc agaggaagac tgtccttgac ttctaacttg
    29101 tcctcggtca tctcaccttt gacggtcccc ttgatatcac tagtctggga atacaagtct
    29161 aacacttgct cgatactctg cctatctttc ccttctaggg actgagcaat ggctgttgcc
    29221 ttttgaccaa tggtttcctg acgatgactc agataagtcg aaggaaaaag aaaataaata
    29281 gctaaatgaa ggcagataac cagaacacta aatatcgaga aggtatagat aaatatcttt
    29341 gcaaataaac ctgttcgttt cattttcgct ccaatttata accaacattg cgcacagtga
    29401 ggatacaatc caagtctagc tttttccgca attccttgat ataaacatca ataacacggt
    29461 caaagggaac ctcatctgtc gctttccaga cggcatcgat aatctgagac cgagtcaagg
    29521 cccggccttc atttttcact agatagtcca gaatttccaa ctctttggca ttgataggca
    29581 cttcttgacc tgcgaggctt gcactgtagc tttcaaagtc caccttggta tccttgtaag
    29641 aaaagattcg tcctgtatcg tagtagcgct tgaaaatcgc gtccaccctc acttttaaga
    29701 gggagaggga gaaaggtttt tccagatagc catctgccaa agaggcaaag gcactcatct
    29761 tgtattcctc atcctgaaaa gctgtcaaca tcaagacagg aacctgactg gttttacgaa
    29821 tctcagctag aacttctaag ccgttaagct tgggcatctg gatatccagt aaaaccaggg
    29881 ccacctcata gctagaaaat tgctccagag cttcctgacc gtccgctgcc tcaatagttt
    29941 catagccaca atccgtcaaa taatcactga ccccctcacg gatcatctct tcatcttcta
    30001 caattaaaat tttcatactt taactgctct ctatttttta tttttcttag aataaatacc
    30061 tactctattt tctattatag tctcttgctg gccttttgtc tgtaagtaac tgatcactag
    30121 ataaaacgtt gtgaaattcc tttctcataa attccatagc tttagtatat tatatttaag
    30181 caataaagta caaagaaaac aactgaaagc aatgattttc accactgctt tcggatttat
    30241 tttgaattgt taaatagcca ttcctatcca ctattcttga atagaaacac aagatgcaat
    30301 ctttattcca gactcatttt ttcaaattta ttcaccatcc agcaagagct cttttggttg
    30361 ttttctaagg agattgcttg aagcaagcgc cataacgaga accactagaa ccaaggcaag
    30421 gacaaaaatg atgataaagt ctgatgtctg aatagaaatg tctaggctcg acaaggtctt
    30481 gctaaagcca tctacttctg caccaccacc aaggttagag gcttgagccg ccttactagc
    30541 ctgtttggca acacctgaag tcacattggc aaggacagtg tttccaattg cacgggcagt
    30601 gtaattagct aggaagtaag cagaaactag agcagggata gcaatcaaga tagattcggt
    30661 gatgaattga cccaagatac ttgcctgctt gaggccgata gagaggagaa ttcccacttc
    30721 cttgcgacgg gcgttgatcc aaaggctgag caagagggca aggaggagaa ctgagaagct
    30781 caagctaccc cagaagagga ggttggccat cttgtacata ccagagatag attgctcaag
    30841 agctgggtag ttagaggagc tcttgacgag tgtgtagctc ttccagttga taccactgat
    30901 gccattcaac tctttcataa catcatccaa gttcttgtct gctgttacaa agaaggttgc
    30961 gtccccataa atggctgtgt cttctgtgta tccataaagt tttgcagcag tgtgaatgtc
    31021 tgtaatagct gtgttttcgt aaagttcttg tgagtaggtt actgctgact tattatgacc
    31081 atcaaagagt cccttgattg tcacttcaac tgtttccttg gctccttttt cattatctgc
    31141 atcgtagata ttagagtcca gtttaacctt gtcccctact ttccagccgt gtttggctgc
    31201 caagtccttg tgcaagagga ttttatcctt gtcgtcgttg gttaagtgct ctccttcgac
    31261 tagtttataa gaaccagaga caaacttgtc ttctttagag gagtcattga cacctgtaat
    31321 catcaagcta cttccaaaac gtttggcacg atcagcagtg agattcttct tggtttctgg
    31381 cgtttcaatc aggtcatatc cagtcaaatc tccgatagcg ttgatacgtt tgacataaga
    31441 ctcaatggcc ttgttttcgg tgattttttt gatgtcttca cccttgatat tcccagcacc
    31501 gcgaggcgtt ccttggttga cgcgacgatt gatttgcatg gagaagctat tggtgatatt
    31561 tttaaaggtc tcctgagaag ccttggcagt agctcccttg attgacaagc cgaccaaact
    31621 caagctcgcc atgaggagaa taatcaggaa gatgacaatc gatttgaaaa acttccttgt
    31681 aacataggca aatgcgttgt gtaacataga ttccctttct agattttgtt ttaatcattc
    31741 tattaaagta agctcaaatt atttactagt attgcgcgtt tcagtcagtt tcttatcctt
    31801 taattcaagt gtaatatctg acgcttgtgc cacttcttta ctgtgagtta cgacaatcac
    31861 acatttacct gttttctggg caagtgattt gagtagttcg acaatatctc cagcagtttt
    31921 aggatccaga tttcctgttg gctcatcagc tagaataact ggagcttctg agaccaaact
    31981 gcgagcaatg gcaacacgtt gctgttgacc acctgataac tggagaacat tccgcttgat
    32041 ctgactttca tccaaaccaa gctcaagaag tgtatccttg cttgcctttt tgttgaccaa
    32101 ttggatattt tccagcggag aaagataatc tatcaagtta taattttgaa agaccaggga
    32161 aatatggtgc atgcgatggt aagaatagcc cttcttacga atatcctctc cttgaaaaag
    32221 gatagaacct tcaacaggac tatctagacc agcaagtagg gacaagagtg tggattttcc
    32281 tgctcctgac tccccaataa tactgtaaaa ttttccgggt tcaaaattat aattgatctg
    32341 atataggact gcttcagcag tattcttata acggtaggta acatcttgta attgtaataa
    32401 agtcatgatt tctccttctt aactaataga tgataaaatt tctttcggtg attttctaaa
    32461 taagaatagg aaacaaaggg ctacagataa gcaactaagc agaactagaa aaacatagga
    32521 ttctgcaaaa gataagatgc tagttgataa actgcttgct ttggctagtg tatcttgtaa
    32581 gcttgcctga tctccacttg ctagtagagt ttggagtagg taagttgtga ttgcgtttcc
    32641 tgcaacaaat gctggaagca aagctccaag agataccaaa actacctcta aacagaattg
    32701 taggaagatc gagctcttgc cttttccaag tgcaagtaaa atccccactt catagacccg
    32761 ttctctcaac cagagagaca aaaccagaat taaggctcca gctcctgcta tcaacatccc
    32821 ataaaggaag atggtcagga aggtttggaa agttgcaact gagtctttga tttgttcaaa
    32881 agccttgttt tccttttcga cttggtagcc ttgattttcc aaggccaagt tttctacctg
    32941 cttcatgagt ccgtccattt ccttaggatt ttctacatag aagcgtgctg cactgacttg
    33001 agcttcacta ttgcccaaaa gggtttggct actttcatag tctgtaaaga cttgattttc
    33061 actgaagtca gaagacaagc ctgtgaattt ctcttgtttt ttaccagaaa agatgccaat
    33121 aatctcaaac tctactgttt gtccttttcc agattcagac tgaccagcat ccaagccaat
    33181 cttgtcatga agtgaaagac cgttcttctt agccaattct tcgtggataa ggattttctt
    33241 ggaatcccct ttttgaaggt gtcgcccttc ttttagattg aaagccgaac tggtaaaggt
    33301 tacatccttg gatgaatcct caagagccgt taagctaacc aagttattgt ctgcagctga
    33361 taaatcatca cgctccacgc tctgctcgcc agtcactgct tccttgtctt ttagttttgc
    33421 gaccgtctca agttcaggag agacattttc cagcccctta atcttgctta cagatgctag
    33481 gtctgacaac ttgaatgtct gaccattctc tatcttctta atagaaaaag atgtattgag
    33541 tgatttataa agattgcttt ctactgtttt gttggacttc atcagagtca aacaggctga
    33601 aattccggcc aataagacca ataaaatcag aaataaaata aaacttctca gtcgctttct
    33661 gctgacataa gcccaagatc tttggattgg attcatttgt cacctccata tttgtaagac
    33721 tattataaaa cccaaatatg aaatgtttat gaaatacgaa aaaaaaaa
//
LOCUS       DAVLZS010000021        32875 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLZS010000021 DAVLZS010000000
VERSION     DAVLZS010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32875
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.021"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(146..913)
                     /locus_tag="VYO88_001057"
     CDS             complement(146..913)
                     /locus_tag="VYO88_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1719169.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(910..1776)
                     /locus_tag="VYO88_001058"
     CDS             complement(910..1776)
                     /locus_tag="VYO88_001058"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1719170.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(1813..3180)
                     /gene="accC"
                     /locus_tag="VYO88_001059"
     CDS             complement(1813..3180)
                     /gene="accC"
                     /locus_tag="VYO88_001059"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1719171.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(3192..3614)
                     /gene="fabZ"
                     /locus_tag="VYO88_001060"
     CDS             complement(3192..3614)
                     /gene="fabZ"
                     /locus_tag="VYO88_001060"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1719172.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(3611..4096)
                     /locus_tag="VYO88_001061"
     CDS             complement(3611..4096)
                     /locus_tag="VYO88_001061"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1719173.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(4099..5334)
                     /gene="fabF"
                     /locus_tag="VYO88_001062"
     CDS             complement(4099..5334)
                     /gene="fabF"
                     /locus_tag="VYO88_001062"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1719174.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(5356..6087)
                     /gene="fabG"
                     /locus_tag="VYO88_001063"
     CDS             complement(5356..6087)
                     /gene="fabG"
                     /locus_tag="VYO88_001063"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1719175.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(6121..7041)
                     /gene="fabD"
                     /locus_tag="VYO88_001064"
     CDS             complement(6121..7041)
                     /gene="fabD"
                     /locus_tag="VYO88_001064"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1719176.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVIPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(7034..8008)
                     /gene="fabK"
                     /locus_tag="VYO88_001065"
     CDS             complement(7034..8008)
                     /gene="fabK"
                     /locus_tag="VYO88_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1719177.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(8127..8351)
                     /locus_tag="VYO88_001066"
     CDS             complement(8127..8351)
                     /locus_tag="VYO88_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1719178.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(8411..9385)
                     /locus_tag="VYO88_001067"
     CDS             complement(8411..9385)
                     /locus_tag="VYO88_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1719179.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(9385..9819)
                     /locus_tag="VYO88_001068"
     CDS             complement(9385..9819)
                     /locus_tag="VYO88_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1719180.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(9913..10698)
                     /locus_tag="VYO88_001069"
     CDS             complement(9913..10698)
                     /locus_tag="VYO88_001069"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1719181.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            11067..12431
                     /locus_tag="VYO88_001070"
     CDS             11067..12431
                     /locus_tag="VYO88_001070"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1719182.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            12434..12805
                     /locus_tag="VYO88_001071"
     CDS             12434..12805
                     /locus_tag="VYO88_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1719183.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            13019..14293
                     /gene="serS"
                     /locus_tag="VYO88_001072"
     CDS             13019..14293
                     /gene="serS"
                     /locus_tag="VYO88_001072"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1719184.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(14318..15217)
                     /locus_tag="VYO88_001073"
     CDS             complement(14318..15217)
                     /locus_tag="VYO88_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1719185.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(15327..15875)
                     /locus_tag="VYO88_001074"
     CDS             complement(15327..15875)
                     /locus_tag="VYO88_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1719186.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(16093..17415)
                     /locus_tag="VYO88_001075"
     CDS             complement(16093..17415)
                     /locus_tag="VYO88_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1719187.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYIFLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(17506..17594)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(17758..20094)
                     /locus_tag="VYO88_001076"
     CDS             complement(17758..20094)
                     /locus_tag="VYO88_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1719188.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(20198..20746)
                     /locus_tag="VYO88_001077"
     CDS             complement(20198..20746)
                     /locus_tag="VYO88_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1719189.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIAYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(20743..21045)
                     /gene="zapA"
                     /locus_tag="VYO88_001078"
     CDS             complement(20743..21045)
                     /gene="zapA"
                     /locus_tag="VYO88_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1719190.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            21132..22013
                     /locus_tag="VYO88_001079"
     CDS             21132..22013
                     /locus_tag="VYO88_001079"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1719191.1"
                     /translation="MASITLTPSEKDIQAFLEHYQSSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSTKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSIIARNLFLENLENLGRELGYQLPSGAGTTSDKVASQILQAYSMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            22017..22631
                     /gene="lepB"
                     /locus_tag="VYO88_001080"
     CDS             22017..22631
                     /gene="lepB"
                     /locus_tag="VYO88_001080"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1719192.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            22759..25125
                     /locus_tag="VYO88_001081"
     CDS             22759..25125
                     /locus_tag="VYO88_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1719193.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTIADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNSIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(25173..26456)
                     /locus_tag="VYO88_001082"
     CDS             complement(25173..26456)
                     /locus_tag="VYO88_001082"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1719194.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(27172..28308)
                     /locus_tag="VYO88_001083"
     CDS             complement(27172..28308)
                     /locus_tag="VYO88_001083"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV1719195.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(28370..28807)
                     /locus_tag="VYO88_001084"
     CDS             complement(28370..28807)
                     /locus_tag="VYO88_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1719196.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(28809..30764)
                     /locus_tag="VYO88_001085"
     CDS             complement(28809..30764)
                     /locus_tag="VYO88_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1719197.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(30788..32557)
                     /locus_tag="VYO88_001086"
     CDS             complement(30788..32557)
                     /locus_tag="VYO88_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV1719198.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            32766..>32875
                     /locus_tag="VYO88_001087"
     CDS             32766..>32875
                     /locus_tag="VYO88_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1719199.1"
                     /translation="MKLTYDDKVQIYELRKQGYILEKLSNKFGINNSNLR"
BASE COUNT         9686 a         7441 c         6228 g         9520 t
ORIGIN      
        1 ttaaaataga ttgttgtagg ctcacattta tagtatattt ctttttttgt ctattttata
       61 gtctatctcc tcaactggca atttttcgac ctgaattgca tttttccata aaaaatgaga
      121 cctttctagt ctcatttagt cattcttagt attttctaaa tcgttgatag cgttcttcca
      181 gcaactcttc tagcggtttt tgtgaaagtc tagccagctc cgtttggagt tcttttttga
      241 cactcttaat cagttcttta ctagaaagtc ctacttcaga aatcacctta tccaccacgt
      301 ccatttctaa cagttcatgc gaagtgattt tcatcagttc tgctgcttcc atggcgcgag
      361 taccgtcctt ccataaaatg gaagcaaagc cttctggact gagaatggca tagatagaat
      421 tttccagcat ccagacacgg tccgcgacag ctagagccag agccccgcct gaaccacctt
      481 caccgataat aatggcgata ataggaactt tcaggtcact catttccatg agattgcgag
      541 cgatagcttc cccttgacca cgttcttccg ctccgacacc aggataagca cctgctgtat
      601 tgataaaggt cacaactgga cggccaaatt tctcagcctg tttcatcaac cgcagtgcct
      661 ttcggtagcc ttctggatgt ggttggccaa aatttcgttt gaggttgtct tgcaaactct
      721 tgcctttttg gataccaacc actgttacag cttggtctcc aagccaacca ataccaccaa
      781 caactgcacc atcatcacga aaagaacggt caccatgtaa ttggataaat tcatcaaaaa
      841 tgcctgtcgc aaagtccaag gttgtcaagc gactctgctc acgcgcttct ctgactattt
      901 ttgcaatatt catctaggac tccctccatg caatctgact aggctagcaa tcgtatctgg
      961 taagtctctt cttttgacaa tagcatccac aaagccatgt tctaatagga attctgcctt
     1021 ttggaaatcc tcaggcaagc tttcacgaac cgtattttca atcacacgac gcccagcaaa
     1081 accaaccaag ctctgtggtt cagccagaat gatatcgcct tccatagcga aagatgctgt
     1141 cacaccacca gtcgttggat ctgtcaaaat ggtcaggtaa aagagaccag catttgaatg
     1201 gcgtttaacc gccgcagaga tcttagccat ctgcatgaga ctcatgattc cttcctgcat
     1261 acgggctcca ccagaggctg tgaataggac aactggcaat ttttcgacag tcgcatactc
     1321 aaacaaacga gtgatttttt cacctacaac cgtacccata gaagccatga taaagttaga
     1381 atccataatc ccaagagcca cagtctgacc tttaataaga gcagttcctg tcacaacggc
     1441 ttcatgcaga cctgtttttt cacgcataga tgccagtttc ttttggtaac cagggaaatg
     1501 caagggatcc ttgctttcaa tccctgtaaa caattctttg aaggttccca tatcaatcgt
     1561 caaagccaag cgttcttggg cagaaatacg aaaggtatag ctacagtgcg gacagatacg
     1621 ttcacttccc agatccttct gatagatggt atgcttacag cctggacact gggaaaataa
     1681 ttcatctgga acctctggct tagcttgagg tttttcccta accgaacgat tgggattgat
     1741 tcgaatatac ttatcttttt tactaaatag agccattgat tccccttttc ggtttaaact
     1801 cttaaagtca ttttattctt tttcttgata tttaggtaag aaggtttcca tcaagaagga
     1861 agtatcataa tccccagcaa tgacattgcg atctgaaatg aggtcaagct ggaaatctgc
     1921 attggtctgc actccttcaa tctctaattc atagagggca cgttgcattt tcatcaaggc
     1981 gtcaaaacga ttttcgccgt gtactatgat tttggcaatc atactatcat aataaggcgg
     2041 aatggtataa cctggataaa ctgctgaatc cacgcgcaag ccaactccac cacttggcag
     2101 atagagatta gtaatcttac ctggacttgg agcaaagtta aaggctgggt tttctgcatt
     2161 gatacgacac tcgatggcat gaccgcgtag gacaatatct tcttgcttaa cagacaaagg
     2221 ctgacctgcc gcaatgcaaa tctgttcctt aacgatatca acacctgaaa caaactctgt
     2281 tactggatgt tctacctgaa cacgagtatt catctccatg aaatagaaat tgctacttgc
     2341 ttcatcaaga agaaattcaa tggttcctgc attctcatag ccaacaaact ctgccgctcg
     2401 aacagcagca gcacctattt catgacgcag cgtttttccg attgcaatcg agggactttc
     2461 ttccaaaacc ttttggttat ttctttgaag agaacaatcc cgctcaccca agtgaatcac
     2521 atgtccatgc tcatcaccta ggatttgaac ctcaatgtgc cgagctggat agataacccg
     2581 ttctatgtac atggcaccat tgccataatt ggccttggcc tcactagagg cagtttcaaa
     2641 ggcagaaacg aggtcatctg gtttttcaac cttacgaatc cctttaccac ctccgcctgc
     2701 tgaagccttg agcataacag gatagccaat tttttcagca acaatcaaag cttcttcaga
     2761 gttatgcact tctccatctg aacctggtat aacaggcaca cctgctttaa tcatctgagc
     2821 acgcgcattg atcttatccc ccatcatatc cataacatga ccagatggac cgataaactt
     2881 gatacctact tcttcacaca tggtcgcaaa tttggaattt tcactgagaa atccaaaacc
     2941 agggtgaata gcttctgcct cagtcaagac tgcagctgat agaactgcat taatattgag
     3001 ataagactct gttgccttgc caggaccaat acaaactgct tcatctgcca aaagcgtatg
     3061 aagagcttcc ttatcagcag ttgaataaac cgctaccgtc gcaatcccca attcacgtgc
     3121 cgcacggata atacgaaccg caatttcacc acgattggca attaaaattt ttcgaaacat
     3181 ggagaacctc cttagttccc aattgcaaaa gtaaggatac cactggctgc aagcttgcca
     3241 tccacttcag cctttgcttc aaccacagct atggtgccac gacgttttac aaaagtcgct
     3301 gtcataacca attggtcgcc tggtacaact tgcttcttga acttaacctt gtccatacca
     3361 gcgtaaaaga ccagttttcc tttattttca ggttttgata actccaacac accagcagtt
     3421 tgcgccaagg cttccataat cagaacacct ggcataactg ggtattgagg aaagtggccg
     3481 ttaaagaaag gttcgttaat ggtcacattt ttgatagcaa caatggtatc ctcgctcact
     3541 tccaagacac ggtccactag aagcatagga taacggtggg gaagagcttc tttgattcct
     3601 tgaatatcga tcatttgata cgtaccaatc ctttaccaaa ctcaaccatt tcttcgttag
     3661 agacgagaat ttccgttacc acaccatcct taggagctgg gatttcattc atgactttca
     3721 tggcttcgat aattaccaat gtttgacctt ttttgacact atcaccaact gtaacgaagg
     3781 caggtttatc tggtccagca gccaagtaaa ccactccaac aagtggactc tctacaagat
     3841 ttccctcagt agccacactt gcttcagctg gagctggaac ttcttctgct acagtctctg
     3901 ctggagcaga tgtaggagct actggactcg gtgttgctag aacgggtgct ggagcgactt
     3961 gagttgcaac ttcaggcaca ggtcttgctt cattcttgct aaactgcaac tcatccgtcc
     4021 catttttata agaaaattct ctcaaacttg actggtcaaa ttgagtcatc aagtctttaa
     4081 tatcgtttaa attcatactt atctattctc ccaacgtttg aaagcaagaa ctgcattgtg
     4141 gcctccaaaa ccaaaagtat ttgaaatagc gtatggaatt tctttctcca agccttgtcc
     4201 ataaacgaca ttagcttcga tataatctga tacttcactt gtcccagctg tcattggtac
     4261 aaagttatga cgcatagctt cgatggtgac gatagcttct actgcacccg cagcccccag
     4321 caaatgtcct gtaaaagact tggttgatga tacaggtact tccttaccaa gaacagctac
     4381 gatagcacca ctttctcctt tttcatttgc aggagttgac gttccgtgag cattgacata
     4441 ggctacttgc tctggagaaa tctcagcttc ttccaaggct agtttgatgg ccttgatagc
     4501 tccctgacct tctggatgtg gagaagtcat gtggtaggca tcacaagtat ttccgtaacc
     4561 aaccacttca gccaggatag tagctccacg tttttcagcg tgttcaagac tttctagaac
     4621 caacatccct gaaccttcac ccataacaaa cccattgcga tccttatcaa atgggatcga
     4681 agcacgagtt ggatcctctg tagtagagag agctgttaag gcttggaaac cagcgatggc
     4741 aaaaggtgtg atagaagctt ctgttcctcc caccaacatc acatcttgga aaccaaactt
     4801 aatggagcgg aaggcatccc caatcgcatc atttgatgaa gagcaggcag tattgataga
     4861 tttacaaaca ccgtttgcac caaaacgcat ggctacattc ccagaagcca tatttggtaa
     4921 agcttttgga agagtcattg gtttgacacg tttgggtcct ttttcatgaa ggcgaagtac
     4981 ctgatcttca atttccttga ttccaccaat accagatgca acgataacac caaaacgatc
     5041 cctattaaga gcctctacat caagattggc atggtttaca gcctcttggg ctgcatacaa
     5101 ggcatataaa gaatagttat caaaacggtt ggtatctttt tttacaaagt atttatcgaa
     5161 cggaaaatct tggatttctg ccgcattatg cacatcaaag tcactatgat caaattttgt
     5221 aatgccacca atgccgattt tcccagttgc taaactattc caaaattctt ctggtgtatt
     5281 tccaattgga gatgttactc cataacctgt taccactact cgatttagtt tcattctttt
     5341 cacctctagc tttcgctaca tacttaagcc accatcaatg gcaatcactt gaccagttag
     5401 ataatcttgg cctgctaaaa atactgtcaa atctgcaacc tgctctgcct gcccaaattc
     5461 tttcatcgga atctgagcta gtgtagcttc cttaatctta tctgataaga tagctgtcat
     5521 atcagactca atcattcctg gagcaatcac attgactcgt atattccgac tagcgacctc
     5581 gcgtgccaca gacttggtaa agccaatcaa gccagcctta gaagcagcat agttagcttg
     5641 accaatattc cccatcaaac caacaacact agacatatta atgatagcac cttctctggc
     5701 tttcatcatc ggtttcaaga ctgattgtgt catattaaag gcaccagtca gattgacctt
     5761 gagcactttt tcaaaatctg cttctgtcat cttgagcata agagtatctt gggtaatccc
     5821 tgcattgttg accaaaacat ctactgaacc cagttctgca atagcttgat caatcatacg
     5881 cttagcgtct gcaaaatctg atacatctcc tgaaatggga accaccttga taccatagtt
     5941 tgaaaactca gcgagcaatt cttctgagat tgccccacga ctgtttaaga caatgttggc
     6001 tcctgcttga gcaaacttgt gggcgatggc aagaccaatt ccacgactcg aacctgtaat
     6061 aaagatattt ttatgttcta gtttcatttt tttcctttca aaacttctac ttattttagt
     6121 ctatttttct aaaagtgcta ctaaactcgc ttgatcttcc acatgagcta agtgagcagt
     6181 ttgatcaatt tttttaacaa aacctgacaa gactttcccc ggtccaatct cgataaagtt
     6241 gcttatgcct gcttcttgca tgaccccaat actttcatag aaacgaacgg gttccttgac
     6301 ctgacgcgtc aagagctgag caatgtcctc tttttgcatc acagcagctt ctgtattgcc
     6361 gactagggga caagtaaaat ctgaaaaact tacctgagct agagtttcag ctagtttctg
     6421 gctagcaggc tcaaggagag cggtgtgaaa gggacctgac accttaagag gaatcaagcg
     6481 tttggcacct gcttcttgca aaagttcaac cgctcgatca actgcaacca cttctccagc
     6541 aatgacgatt tgtgcaggtg tgttatagtt ggctggaata accactccaa gttcagaagc
     6601 tttttgacag gcttcttcaa tgacctctac tggcgtattg agaactgcta ccatcttgcc
     6661 agagtcagca ggagccgctt cttccatata ggctccacgc ttagctacca aggcaaccgc
     6721 atcttcaaaa tccaaggcgc cgcttgccac caaggcagag tattctccaa gagacaaacc
     6781 agcaaccata tcaggctgat agcccttttc ttgcaataaa cggtagatag caaccgaagt
     6841 cgctagaatg gctggttgcg tatagcgggt ctgattgagt ttgtcttctt ccgtatcgat
     6901 gagataacgc aaatcataac ctagcacctg actcgctcga tcaatcgttt ctttaacaat
     6961 cggatactga tcatagaaat cccgtcccat ccctagatac tgggcacctt gaccagcaaa
     7021 taaaaaggct gttttagtca tttcttacaa ctcctgtcca gcgagaggct tcttcttgaa
     7081 ttttcttagc ggctccgtaa tacaaatctt ttaggatttc ttcagctgtt tcttctttag
     7141 aaacaagccc tgcgatttga cctgccatga cagagccacc ctccacatca ccgtgaacaa
     7201 ctgctttggc tagggcacca gctcccattt gttcaaagat ttctaaatca ggatcttcct
     7261 gcttaaaggc atctttttca gccagttcaa aatctctagt caactgattt ttaatagcac
     7321 gaacagcatg accaaagtgc tgagctgaaa tcgtagtgtc aatatccctt gcttttaaaa
     7381 ttttctcctt gtagtttgga tgggcattcg actcttttgc aactacaaac cgtgtcccca
     7441 cctgtacagc ctctgcacct agcataaagc cagccgcagc accttcacca tccgcaattc
     7501 ctcctgcagc aataacagga atagatacag ctgtggctac ctgtcgcacc aaggtcatgg
     7561 ttgttaattt accgatatgc cccccagctt ccattccttc tgcaataaca gcgtctgcac
     7621 cgattttttc catgcgttta gctaaagcga cactaggaac gacaggaata acgattatcc
     7681 cagcttcatg gaaacgttcc atatacttgc ttggatttcc tgctcctgtt gtgacaactt
     7741 taacaccttc ttcaataacg agatccacga tatcttccac aaagggagat aagagcatga
     7801 tgttgacccc aaagggttta tcagtcaatg atttgatttt atcaatattg gccttgacaa
     7861 cttctttcgg ggcatttccc ccaccgataa ttcctaatcc tccagccttg gaaacagccc
     7921 ctgccaaatc accatcagca acccaggcca tccctccttg gaaaatagga tagtcaatct
     7981 tcaataattc tgtaatacgc gttttcatag tgcctccaac cttccttgct tacgtaatag
     8041 ttcgatttca ccataatttg acagtcaaac tattacctaa acaagaggga gtgggtttct
     8101 ccctactcct tctactaata ttctgcttat tttgcttgct cttcaacgta agcaaccaag
     8161 tcaccaactg ttttcaagtc attttctgct tcgatttgga tatcaaaagc atcttcgatt
     8221 tctgagatta cttggaacaa gtccaatgaa tctgcgtcca aatcatcaaa agttgattca
     8281 agtgttactt ctgatgcgtc ttttccaagt tcttcaacga taatttcttg tactttttca
     8341 aatactgcca tgataggact cctttaaaat aaatagtttt tttataacaa tgtgttcacc
     8401 acatgattac ctaaattgta agaatgagcg tgccccaggt caagcctcca ccgaagcctg
     8461 atagaagaac agtctggcta ccatctaaag ggatgagacc ttgttctaca cactctgaaa
     8521 gtaaaatcgg gatactggct gcactggtat tgccatattc catcatattg gctggaagtt
     8581 tggctcggtc aacaccaatt tttctagcca tcttatccaa aatacggtca ttggcttgat
     8641 gaagtagcag ataatccaag tctgtcacct ctataggaga ttcatcaata gtctgcttga
     8701 tagacttggc tacatctcga atggcaaaat caaaaactgt gcgtccatcc atcttcaaaa
     8761 acgaatctgc actttcttga tctgaaaatg gagaatgcaa acctgaatgc ccataagtta
     8821 aacactcgct gcgacttcca tcgctattga gactctcagc taagaaatgc tcttgctcgc
     8881 tagcttctaa caagacacca ccagcaccat ctccaaacaa cacagctgtt gatcgatccg
     8941 accaatcgac tgccttagag agggtttcac taccaatcac caagcctttt tgaaagcgac
     9001 cagaagcgat aaacttttca gcagttgaaa gagcaaatac aaatccactg caagccgcgg
     9061 ttaagtcaaa agcaaaggct ttattagcac caatattagc ttgaacacga gcagctgtag
     9121 agggcatcat cgaatctgga gtaatggtag ctaggatgat aaaatccagt tcttctcctg
     9181 ttattccagc ttttgccatc agtttcttag caacctctgt agccaaatca ctggtagatt
     9241 ctgttcttga aatatgcctt tgtcgtattc ccgttcgact tgaaatccac tcatcattgg
     9301 tatccataat ctgagccaag tcgtgatttg taaccacttg ctctggcaca taatgagcaa
     9361 cctgacttat ttttgcaaaa gccattattt caaatcctcc aaaaattggt aaagattagt
     9421 caagccttta cccatgacag caatttcttc ctcgctcatg ccatcaataa ttttttctac
     9481 catggccttg tggaagcgtt tatgcagtct atgaatcaag cgacccttct ttgtcaaatg
     9541 cagatgcacc acacgacgat cctgttctga ccgaactcgc tcaatgtagc ccttacgctc
     9601 taaattgttc aaacttgtcg taacagttcc aagagttacc atcaactctt ttgacacttg
     9661 acttggagtc acatctggag ccttaccgat gacatcaatc gtatgcattt ctttgatgga
     9721 gatatcctta aaacgactac ctctcaagtt cacttcctca attacaagga cattgttaaa
     9781 tatagatgtt aaatattcat tgattcgttg gtagtccatt tttcatatcc ctccttcttc
     9841 aaaaaacttt tacaatcaaa acatttgaca gaaagaatta tatcaaaatt caaagaatga
     9901 tgcaagtatt ttttattttc ctgtaaattt aggtcttctt ctctccgaat gagctcgcac
     9961 tccttctttg aaatcctctg tttgagctaa ggatttctgt aggttcagtt ctaaagtagc
    10021 gtaaccctgc cagtctttaa attggctctc ccaaaccaac ttcttaatgg cagcatagga
    10081 attacttgaa gcacgtctta attttttaag aagctgttct ctcgtctttt caagtttttc
    10141 agcttcagaa acgcggtaaa ccaaccccca ttctagggct ttttctgccg ttaaagcctc
    10201 tcctgtcata gctaattgag cagcacgcgt cacaccgata ctgcggctca agagatgaat
    10261 tccccctgca tctggagcca aaccaacacc aacaaaggct tggataaact tagccttatc
    10321 cgtcgccaaa cagaaatctg ccgcaacagc catattcgct gcggcacctg caacagcacc
    10381 gtcaacttcc attaaaacag gtttggctat ttgcttgatt ttataagaaa tcgtattgac
    10441 caactctgcg atttttgtca atgatggaat atcatcctca tccactgccc gcttcatctc
    10501 taccaaatct cccccaactg agaagacctt tccattggca ttgattaaga taaaatgcac
    10561 agctggattt tcttctgcca aagtcagagc ttctaaaatc tcctcacaca tgggaatatg
    10621 aaaaccattt gcgacctcag gacggttcaa ggtaaggatt gccaagtcct cttcaagctg
    10681 ataaataatg tgttccatca gggctccttt ttattttata agcagtttat actcttcgaa
    10741 aatctcttca aaccgcgtca gcttccatct gcaacctcaa aacagtattt tgagctgact
    10801 tcgtcagtct tacttacaac ctcaaagcag tgctttgagc agtctgcggc tagcttccta
    10861 gtttgctctt tgatttcatt gagtgttaaa ttatttcact gtcaaagtat atctttttta
    10921 ggagcagaaa gcaagaaaaa atcgactgaa agtgtctcag ccgataagaa aggctcgctt
    10981 taggctagaa agcatcttat tttcttcatt gaaaaaagcc tttctttctg ctataatcgt
    11041 ataaaatact tactttagga gttcttatga aagttgttaa atttggaggt agttctcttg
    11101 cctctgctag tcaattagaa aaagttttaa acatcgtcaa aagcgattca gagcgtcgtt
    11161 ttgtagtcgt ttctgcgcct ggtaaacgca atgctgaaga tactaaggtt acggatgccc
    11221 tgattaaata ctaccgcgac tatgttgcgg gtaacgatat tagcaagagc caaagctgga
    11281 ttatcgaccg ctatgctgct atggttagtg aattgggact aaaaccagct gtgctagaaa
    11341 aaatttctaa aagcattcac gccttggcca ctcttcctat tgaagaaaat gaatttctct
    11401 acgatacttt cctagcagcc ggtgaaaata acaatgccaa attgattgct gcctacttta
    11461 accaaaatgg tatcgatgca cgctatatgc accctagaga agctgggatt gtggtcacaa
    11521 gtgaacctgg tcacgctcgc atcattccat caagttatga caagattgaa gaattgacaa
    11581 acaccaatga agtccttgtc attcctggtt tctttggtgt cactaaggaa aatcaaatct
    11641 gtactttctc acgtggaggt tctgatatta caggttctat cattgctgct ggtgtcaaag
    11701 ccgacctcta tgaaaacttt acggacgttg atggtatctt tgcagcccac cctggtatta
    11761 tccaccaacc acactcgatt cctgagttga cctaccgtga aatgcgcgag ttggcctatg
    11821 caggcttctc agtccttcat gacgaggctc ttcttcctgc ctaccgtgga aaaattcctc
    11881 tggttatcaa gaataccaac aaccctgacc atccaggtac tcgtatcgtt ctaaaacaca
    11941 gtaatgatga atttccagtt gtgggaattg ctggtgactc aggctttgtc agcattaaca
    12001 tgtcgaaata cctcatgaac cgtgaggttg gatttggccg caaggttctg caaatcctgg
    12061 aagaacttaa catcggttgg gaacatatgc caacaggtat cgacgatctt tctatcattc
    12121 tccgttctcg ccaactaact cccatcaagg aagaagaaat cctgcgtcag ttggttcaaa
    12181 aggctaaagt agatcatgca gaaatcgaac acgacctttc tatcattatg attgttggtg
    12241 aaaaaatgaa gagccacatc ggagtgactg ctactgcgac acgcgctcta tctgaaaaca
    12301 aaatcaacat ccagatgatg tctcaaggtt ctagtgaagt ttctattatg tttgttgtca
    12361 ataaagacca agagaaagca gcaattaaag ccctctacaa tgcctttttt ggagaaagta
    12421 aggaagacta agcatggccc aatcacttaa caaaacagta ctcctcagta cgacaggcac
    12481 ttcctacctc tctatcgctg ggaaagttgg gaaattcctt gtcggagatc aggctttgga
    12541 attttaccca gatgtcaatg tcgaacaatt tatccagatt ccttggagcc atatcaatca
    12601 gattggagcc aatgtcactg gacgcaaaat cagccgccac ttcgaagtct ttacagacaa
    12661 aggaaaattc ctctttgctt caaaagactc aggtgccatt ctcaaaattg cacgcgaaaa
    12721 actaggcaat gacaaggtcg tcaaacttcc gaccctgatt cagacaatta gccaaaaatt
    12781 taaaaatcta tttgcaaaaa agtagaaact ttagtataat catagcaacg gataagtagg
    12841 ttatcttctt ctttcagaaa gtctgcgggt actgcgagca gatagggggg ataggtgaaa
    12901 ttctaccgtt agtaacaatt acatacacaa tcaagtgcac acctgtgaag ttggatggaa
    12961 ccgtggccct gccactccaa cgttttgtca ggcgtgcttt tttcataaag gagttcttat
    13021 gttagatatc aaacgtattc gtacagattt tgaagctgtc gcagaaaaat tagctacacg
    13081 tggtgtagat gctgctgtct tgaatgaaat gaaagaaatc gatgctaaac gtcgtaacat
    13141 cttggtcaag gttgaaactc tcaaagcaga acgtaacaca gtttctgctg agattgccca
    13201 agctaagcgc aacaaggaaa atacagatga caagattgct gccatgcaaa atctatctgc
    13261 tgaggttaaa gccttggatg ctgaattggc agaaatcgat gctaaattga cagaatttac
    13321 aacgactctt ccaaatatcc cagctgacag cgttcctgtt gggactgacg aagacgacaa
    13381 tgtggaagtt cgccgttggg gtactccacg cgagtttgac ttcgaaccta aagctcactg
    13441 ggatctcggt gaagaccttg gtatccttga ctgggaacgc ggtggtaagg taacaggcgc
    13501 tcgcttcctc ttctataaag gcctcggtgc tcgtttggaa cgtgctatct acaactttat
    13561 gttggatgaa catggaaaag aaggctatac tgaagtcatc acaccttaca tagtcaacca
    13621 tgattctatg tttggtactg gtcagtatcc aaaatttaag gaagatactt ttgaactcag
    13681 cgataccaac tttgtcttga ttccaactgc tgaagttcct ctgacaaact actaccgtga
    13741 tgaaatctta gacggcaaag atcttccaat ctacttcact gccatgagtc cgtcattccg
    13801 ttctgaggct ggttctgccg gtcgtgatac gcgtggcttg atccgtttgc accaattcca
    13861 caaggttgaa atggtcaaat ttgccaaacc agaagaatct tacgaagaat tggaaaaaat
    13921 gacagccaac gctgaaaaca ttcttcaaaa actcaacctt ccataccgtg tcgttgctct
    13981 ctctactgga gatatgggct tctcagctgc gaagacttac gacttggaag tgtggattcc
    14041 agcacaaaac aattaccgtg aaatctcaag ctgttcaaac acagaagatt tccaagcccg
    14101 tcgtgcccaa atccgttacc gtgatgaagc agatggcaag gtgaaactcc ttcatacctt
    14161 gaacggttct ggacttgcag ttggacgtac agtggctgca attcttgaaa attaccaaaa
    14221 tgaagatggt tctgtgacca tcccagaagc acttcgtcca tacatgggtg gagctgaagt
    14281 catcaaacca taaaaaataa ggtttagcta tttctagcta gacctttttt cgtaaccaaa
    14341 tcagataagc acccagtaca aagaataaaa tagttaggca tataatggtt tcagccaata
    14401 ccaggtaatc cagaaatgga agtttcaaaa ttccctgagc catcttgagc gaggtcgctg
    14461 tgataatggt tgggaaggtg agggctgaga aggctggttg aaaaccttgt tttaaaatgt
    14521 tgggcagacg agttaaaaca aagaaaaaga aggattgaga agccaaaatc atgacaatca
    14581 agacccaagt cggcaggctg gttcctccta ctcgaactag agaagccaag agtagagaga
    14641 aaggagcaca gtagattcct tcttgtccaa gcaaggctag tgggagtgga tgtttcttta
    14701 aatcgctata aataagggga tagagataga aggtcaagag aaaaccaaaa ctcaaggtcg
    14761 cataggcaat ttcgataata cctaccagag gataggtcaa ggcagccact gctatcccca
    14821 catagagaac cgtccaactt ggagtggcat gaaccctccg ccctggacaa gcaaacttga
    14881 tggtaaaacc agcaatcaag gtcaaatcca agagaaatga aaaccaccaa atcccttgtg
    14941 ctaccaaagg aagataagag aatacgcgaa agacataggt cgataaaatc atcccagcca
    15001 taggaaaggt tgccattcct gacaaaagag ggggcttggt caattcttgc ttggtttctt
    15061 tccaattaaa gagatgcaga attagaaagt aaatccataa aaccaaacca gtcagactaa
    15121 aaagatggga tagaaccggc aacgtatcta aaataagatt tccagctcct gccaaaccta
    15181 gcaaacaacc tgaaaatact aaggggagtt ttttcatcct aacctccaat aatcatgtta
    15241 gtttcagtat aacataaaag cgcttaaatg aggatttaaa aaaacgaagt ccgcttattt
    15301 cagacttcat tttactcaga tatgaattag gcataaggtt gcaattctgg attaattggt
    15361 gtattagcta agttgttggc atagttacag aggattgcta ggctgacacc aaaaaccaca
    15421 tccaaggcat tttgttgagt gtagccagct tctaaaaact cagacaaggc ttcatctcct
    15481 acacgaccct tggtattgat aactgccaag gtaaacttag ctagggtatc caatttagga
    15541 tctgtttcaa ttggagtacg attgcgaaga gcttgaatca agtcatcatt catctggatt
    15601 tgtttgatgg aaaaggctgt gtgacctgcg acacagaagg cacaaccatt ggtcacggct
    15661 gccgtgattt gcaccacttc acgctcaacg ggtgtcaggc tgttgcgacg gtggatagat
    15721 gagacaattt ggtaggcttc taaaacagtc ggggcattgg ccaagagacc gattaggttg
    15781 ggaatatagc cattgttgtc tttttctact gtttcaagaa tttctttcac ttctgctggt
    15841 gctgactcta ctgtatggat agtaaatgtt gtcataagat acctcttttc ttattattga
    15901 cactaatatt attggaaaat cttataaaat cctgattcct aagtttatct aagataaagc
    15961 tttattctct cataagattt tcgttgttat attagtttat cacacttcca atcacttgca
    16021 taatatatat tatatatcag gctgataaaa attatttata ggcaaaaaaa tcacacgagc
    16081 tgtgtgattc cattatttgt caaaatactt tttagtttca gcaataacga ctggcgacaa
    16141 gaccaagagg gcaatcaagt ttggcagagc catcaaggcg ttaacgatat ctgcgataat
    16201 ccagaccata tccaactcga taaatcctcc taacaagacc atgagcacaa aaaccacacg
    16261 gtagagccag ataaagcgag ccccaaagag gaactcaaaa cagcgttctc cgtaatagtt
    16321 ccaacctaga atcgttgtaa aggcaaaaag tacaaggaag atggtcaaga gggcaggccc
    16381 aaagtgtgaa aagactgttg agaaagctga ctgagtcaag gcaaccccat tcaagtcacc
    16441 actccaaact ccagttacca agatggtcaa accagttaga gtacaaatga tgagggtatc
    16501 aataaaggtt cctgtcatgg aaatcaaacc ttgctctact ggttcatttg tcttggcagc
    16561 tgcagctgca ataggagcag aacccagacc agattcgttt gagaacacac cacgcgccac
    16621 accattttga atagccatcc gaacgctagc accagcaaat ccacctaccg cagcaagggg
    16681 actaaaagct gaggtaaaga ctaaagcgat tgtgccaggg atttttccga tattaaagaa
    16741 aataactgta agagttccta agatataaat gagggccata aaaggaacaa cagtagttga
    16801 aaccttagaa atagacttga gtccaccaaa gactgcaatc gctacaaaga cagacaagac
    16861 gagagctgtg atggctggcg aaatcgtcgt tgtattttgg atagattctg taatcgagtt
    16921 gacttgggtg aaggttccga ttcccaagag agcaaccaat actcctgcta ctgcaaacaa
    16981 aacagcaagt ggtcgccact tttctcccat ccctagaaag atatagtgca tgggacctcc
    17041 cgctactgca ccatggtcgt ccttggtgcg gtatttgatg gccaagagtc cttccgcata
    17101 cttggtagcc attccaaaga aagccgccat ccacatccaa aatagagctc ctggtccacc
    17161 aaccttgata gccgtcgcaa ctcctatgat atttcctgtt ccaacagttg atgccaaggc
    17221 tgtacacaga gctgcaaaac tggatacatc accatgtccc ttatcctgga taaaaataag
    17281 ctgaaaggcc ttgggcagac gcaaaacctg caagagtcct agccgcatgg ttaggtaaat
    17341 ccctgttccg accaataaaa tcaagagggg cggtccccaa gcaaaagcat cgattgattt
    17401 aagcaattct aacatttcct tctcctatcg tttcaacccc aaaagaaaga gcacatgcaa
    17461 gatacatgta ctctggaatg cttagataaa tgctaaaaag cggtctatcc tagctctgtc
    17521 cttttacctg agagtttgag cagttgcctg ccttgcccct tcggtgcctt tacggtctct
    17581 ccagagttcc gtccatttac agtcatggaa aatcaaacga ttccccactt ctattaaact
    17641 tcattcggtg ttggtattta attgattcta attttacaaa aaatgttggc ttttgtcaat
    17701 gtgtttatta gtaaaaatta gttcaacagt ttttacttta taaagtccag aatactgcta
    17761 tcctttaaaa gtgacaatag tcgcaccact gcctccagca ttttgtgggg catagccgaa
    17821 actcttgaca tgtttgtttc tttgcaagta tttggtaact ccttcacgga tgactcctgt
    17881 tccgatacca tggatgatat caacttgagc catattgtta agcaaggctt ggtcgatgaa
    17941 ggtatctagc tcattcatgg cttcttcata gcgcttgcct cgaagatcca gtctagcttg
    18001 aggtcctcgc ccagaagttc gtttcacaac attgacctgt ttcttcttga ctggtttttc
    18061 ttgctgggct tgaacaagat caaactcttt ctcttccaag gtcatcttaa tcaagccaac
    18121 ttgggcttcc cagcgaccgt ccttgagttg actggtcaag gtaccacgct gaccataact
    18181 gagaaccacg atatcatctc ccacctttgg agctcgtttt ttcttggcct tttgaaggac
    18241 cttattttta gacaagtcca ctttttcagg agccaatttt ttcaacttgg ccttggcttc
    18301 aatgatttcg tggggcttga gttgggattt actgtggaga tttttgagaa tctggtcact
    18361 ttcacttagg gccatatcca caatctcagc agcctgttca cgcgccttgt taagctcggt
    18421 ttccttttca cgattaagct cgttgtagag tttttttagc gcacggttca tcttgagatt
    18481 ttcttgctcc acctcacgga tattgtccaa acgtttgcgg ctttccagcg tctgctcttc
    18541 taattgctca atgatacgat tgacgtcatt gtcctgatcg atctgctgac tggcatctcc
    18601 tacgataact tcagataggc ctagacgttt ggcaatttca aaggcattac ttcggccagg
    18661 aacaccctgc ataaagcgat aggtcgggcg aagagttgca gtatcaaact ccatactggc
    18721 attttgcaca aaggctgtct caataccgta ggccttgagt tctggatagt gggtcgtcgc
    18781 catggtcttg atttgacgca ggcgaaggtc ctccagaata gccatggcaa gggctgctcc
    18841 ctcttgggga tcagtaccag cccccaactc atccaaaagt aagagtgaat gttggttgac
    18901 cttgccaaga atatccacga tattggtcat atggctagag aaggtagaca agctctgctc
    18961 aatagactgc tcatctccaa tatcagcaaa gatttcttca aaaataccaa cacgacttcc
    19021 cttgtctgct aaaatcggca atcctgactg ggccatgacc tgtgtcaagc ccagagtttt
    19081 gagcatgatg gtcttcccac ctgtattggg acctgtaatg acaatagctg ttaaatcttg
    19141 accaaaatag acatcatttg cgacggcatt tttgaccaaa ggatggcaga catggagcag
    19201 ttgaatctct tgattttctg acagctgagg cacgactgct tgtctttctt ggataaatcg
    19261 aaccttggca cgaatcaagt ccagatgacc gataatccaa gcgtcattag caatctcagc
    19321 cgcatgaggg cggacacgct cagaaatttc ttggagaatg cgaagcattt catagcgctc
    19381 atctgctcgc agactagcaa tttcttcgct cagtttgact acctcacgtg gttcgatata
    19441 gacggtgttt ccactagcag aaatatcatg aacgacacct gcaatcttat tgcggtaggt
    19501 gtttttgact ggtaaaacct gacggccatt tctgctagca acaattcctt ccgtcaacat
    19561 ctgcgctttt tgcttgagca agtcttgtaa aacatcgcgt acctgactct cgctatcatg
    19621 tatttttcga cggattcgcg ccaattcttc actggcaaaa ttttcaatga aacccgcatc
    19681 attaaaggcc tgaagatttc cttgtaattg cggaaaatca tgtaatttct caaaccaaag
    19741 ggctaattct tccaagctga cattttccag attggcgtaa aaactttgaa gttctcggct
    19801 ggtaagaagc acgcgtttca agagtaggaa ctcctcgata ttgagatccg ctcccatctc
    19861 caacctcttg cagactcctg caatttcctt agttgagaga atagtaaaat gcggttgctc
    19921 gacgaaaaga gcctgcattt ctttcatctc agcaaaagcc tgtttgattt tatctgcttt
    19981 ggcagtcgga gccagctgtc tcaattgctc caagccctgc tcggtcaaca aatgaggctc
    20041 aaacaaggcc ttgaccttat cgaactctaa tgtttctaat attttcttat tcatctttat
    20101 ttccttgtct ttgaatgtct aggtgtggta gctttttaca ttctgataga ttcgagtcaa
    20161 atctgtaaac aaagggctag gaaaactcct gcccttttta tccgattaaa tttgtcaccc
    20221 agatttgttt gagccaactg gttgttatcg gtatgctctg gatgatgtgt tttgcgacga
    20281 tactcttttc aagaggattt tgtataactg ccatggggat ggtcgccaag attgtcaagg
    20341 ccatttgcaa gacaaataag gtcaccaaca tggacaagat acctgctgaa acttggaaca
    20401 acttaccacc cagttttttg ctaggaatca agtgtaagag aagaccaagc aaacgaccaa
    20461 tgctatagac aatcccaaat acaagcaagt aggcgatacc tgcataaaag accttatcca
    20521 gctgaaagag ttgatccgat gggaaaaaga aagtcccctg accttcctgc gaatttgcat
    20581 aagggagcaa taaatggaat tgctctccaa gccccttata aaactggcca gccataaaag
    20641 ccgatgccat ggctgaaatc aggtaataaa cctgtaagag caggcctctc cgatagccga
    20701 tataaaatcc ccaaaccaag accaatagaa gaaggaatga aatcataagg aatcctcaat
    20761 cttgctctgt tcttgcttac aagtcacaag cttgtgacgg agttcttcta gctcttgctc
    20821 cttatcgtca aattcaatct cacggctgag ctgagttgat aaacagttga ctgccaacaa
    20881 aagagcgatt gtttcatcat ctgcgctagg catttgttct ttaattgctt ggtatttttc
    20941 tgtcgcaacc ttagcgattt cctccataaa aaggttatca tgttcgcttg tcaaggttaa
    21001 cgattttttc ccgaatgtaa atttgaatcg atttagattt gccataaaat tcacctcacg
    21061 atattatacc aaaattcgct aattttgtca gtttttacaa attttactgc ttttgtggta
    21121 caatagaaac tatggcaagt atcacactca caccaagcga aaaggatatt caggcttttc
    21181 ttgaacacta tcaaagcagt ctggctccta gcaagaatcc ctatatccgc tactttttga
    21241 aactacctca agcaacggtt tctatctata cttctggaaa aatcttgctt cagggtgaag
    21301 gggctgaaaa atacgccagt ttctttggct atcaagctgt agagcaaacc agcggacaaa
    21361 atcttccttt aattgggaca gatgaggtgg gaaatggttc ctactttggt ggacttgcag
    21421 ttgtggctgc ctttgtcaca cctgaccagc atgccttctt acgaaaactc ggtgtggggg
    21481 attctaagac tctgaccgac caaaagatcc gtcagattgc ccctatcctc aaagaaaaaa
    21541 tccagcacca ggcactgctg ctctcaccaa gcaagtacaa cgaggtcatc ggagaccgct
    21601 acaacgctgt ttcggttaag gttgccctcc ataatcaggc tatctatctc ctccttcaaa
    21661 aaggtgttca gcctgagaaa attgtgattg atgcctttac cagtactaaa aattatgaca
    21721 agtacttggc tcaagaggcc aatcgtttca gcaatcctat cagcttagaa gaaaaggctg
    21781 agggcaaata cttggctgtt gcagtttctt ccatcattgc gcgtaatctc tttctggaaa
    21841 atcttgaaaa tctgggacga gaactgggct atcaacttcc aagtggagct ggaacgactt
    21901 ccgataaggt ggctagccag attttgcaag cctatagtat gcagggactc aacttctgcg
    21961 ccaaattgca ctttaaaaac actgaaaaag cgaaaaaacg cttagaaagg taagttatga
    22021 attcatttaa aaatttctta aaagagtggg gattgttcct cctaattctg tcattactag
    22081 ctttaagtcg tatctttttt tggagcaatg ttcgcgtaga aggacattcc atggatccga
    22141 ccctagcgga tggcgaaatt ctcttcgttg taaaacacct tcctattgac cgttttgata
    22201 tcgtggtggc ccatgaggaa gatgggaata aggacatcgt caagcgcgtg attggaatgc
    22261 ctggcgacac cattcgttac gaaaatgata aactctacat caatgacaaa gaaacggacg
    22321 agccttatct agcagactat atcaaacgct tcaaggatga caaactccaa agcacttact
    22381 caggcaaggg ctttgaagga aataaaggaa ctttctttag aagtatcgct caaaaagctc
    22441 aagccttcac agttgatgtc aactacaaca ccaactttag ctttactgtt ccagaaggag
    22501 aataccttct cctcggagat gaccgcttgg tttcgagcga cagccgccac gtaggtacct
    22561 tcaaagcaaa agatatcaca ggggaagcta aattccgctt atggccaatc acccgtatcg
    22621 gaacatttta agaaacctaa gaggccgaga atcaccaatc tcagcctctt cttctatcgt
    22681 gagaaaatga ttggtaacta tctaaactta ccagaacaga aacacctcaa ctctcaccta
    22741 ttcatgcaaa ggaattttat ggaagtttat ttttcaggaa ccattgaacg gattattttt
    22801 gaaaatccca gcaattttta tcgcatcctc ctcctagaaa tcgacgatac ggacgcagag
    22861 gattttgatg attttgaaat cattgtcaca ggaaccatag ctgatgtaat tgagggcgaa
    22921 gactatactt tttgggggca aattgtccag cactccaagt atggagaaca actgcaaatc
    22981 agtcgttatg atcgcgcaaa accaactagt aagggcttgg tcaagtactt ttcaagtagc
    23041 catttcaagg ggattggtct caagacagct cagaaaatcg tggataccta tggcgaaaat
    23101 accattgacg aaattttgca acacccagaa aagttagaag gcatcgcagg actctctgcc
    23161 aaaaatcgcg aggctttcgt ctccactctc cgtctcaact acggtacgga gatggttttg
    23221 gccaaactag ccaactacgg cattcccaac aaactagcct ttcagattca agacttttac
    23281 aaggaagaaa cccttgatgt ggttgaaaat tatccctacc aactggttga ggatatcaag
    23341 ggtttgggct ttaccattgc tgaccaacta gctgaggaac taggcatcga aagtcaggct
    23401 cctgaacgct tccgcgccgg tctagttcac agtctttttc aggcctgtat ggaaacagga
    23461 gacacctatg ttgaagcacg ggatttgctg gaacaaaccc ttactctcct tgagtcttcc
    23521 cgtcccgtgg aactagaccc cagccaagtt gcccaagagc tctcctacct gatcgaagaa
    23581 gacaaggttc agcagattga taccaagatc tttgacaaca gcctcttttt cgctgaggaa
    23641 ggcatccgca gtcacttggt tcgtatcctt gaaaaaggaa aacagaagag tcatgattta
    23701 gaaaccattc aaaaacatat cactactatc gaggaagagc tgggaattga gtatgataac
    23761 attcaaaaac aggctatctg tgatgctatc cagaataagg tctttatcct gacaggtgga
    23821 cctggtactg gtaagacaac tgttatcaat gggatcatcg ctgtttacgc cttgttagag
    23881 ggacttgacc tcaggaagaa aagcaacctg cccattcttc ttgctgctcc aactggacga
    23941 gccgctcgcc gcatgaatga attgacaggt ttgcctagcg cgaccataca ccgccacttg
    24001 ggaatgacag gtgacgatga taccagtcat ctggaagatt acctagatgc tgactttatc
    24061 atcgtggatg aattctctat ggtggatact tggctggcca atcaactctt ctccaatatc
    24121 tcttctaaca gtaagatcct catcgtaggt gacagtgatc agctaccttc tgtcagtcct
    24181 ggacaagttc tagcggatct gcttcatatt cctttgattc ctcagactcg cttggaaaaa
    24241 atttatcgac aaagcgaaga atcaaccatc gtcaccctag ctagtcagat tcgacagggc
    24301 atcttgccag ctgatttcac ccaaaaaaaa gctgaccgtt cctactttga aattgctagt
    24361 ggccatattc ctgccactat tgaaaaaatc ttaggtgccg ccctcagaaa tagtattcct
    24421 gcccgtgata tccaagttct ggctcctatg taccgaggga cggcagggat tgatgctatc
    24481 aatcagctca tgcaagacct gctcaatccc ccacaaaaag atcaactcag ttttgaagct
    24541 cctcagtgcc actatcgtaa gggagacaag gtcattcatt tggttaacga tgctgaaatc
    24601 aatgtcttta atggggattt aggagctatc acagacctga ttcctggtaa atacaccgaa
    24661 tcgaaacaag acgagattgt cattgatttt gatggtaatg aagtctctta cccccgtaac
    24721 gaatggtaca agattcgctt ggcctatgcc atgagtattc ataagtctca gggaagtgag
    24781 ttcccagttg tcatcctacc gattactagt gctagccgac gtatgctgga gcgaaatctc
    24841 atctacacag ccattacacg tgccaaaagc aaactcatct tactaggcga attacaagcc
    24901 ttcgactatg ctacccaaca catcggaact gcccgaaaaa cctatctgat tgaacgcttc
    24961 agtgatctac tggagaatgt tgaagaaaag caacaagctg tctctgaaac agtcacatca
    25021 agtgcctctg aacaatccta catcctaacc gaagaaaact gggacagcat tccagccatg
    25081 attgggatta cagacacaga cctcaaagag atttttggaa aatagtacat cagaaaaccc
    25141 accaattcag gtgggttttc tgtttattaa gattatttta ctgttgctgt gcttgtgatc
    25201 aattcaacag cttttttgat agtgatatca tgtttcaaca tgtcagctga aagcaagttt
    25261 tgaacttgtg caacttccat gttgtagtct gctgccaatt gctcaacttc tttttggatt
    25321 tcttcttctg aagcatcaaa tccttcagct ttggcaactg cttcgataac aaggttagtc
    25381 ttagtacgtg actcagcttc tgcttggtat tggttatgaa ggtcttcttg agtagttcca
    25441 gtgatttgga agtacatgtc agggttgatc ccttgacgtt gcaagttccc aaggaattca
    25501 tttactgaac ggtgaacttc ttcgtggatc atttcttctg gaagttctac gatttcagcg
    25561 ttttctacag ctgtatcaat tgctgcacct tcaactgcat ctttgtaagc ttcttcttta
    25621 gcagcagcca attctttgcg gtatttttct ttcaagtcag caagtgtttc aacttcttca
    25681 tcaatgtctt ttgcaagttc atcgtcaaga gctggaactt ctttagcttt tacttcgtgg
    25741 atagttgtca cgaatttagc ttctttacct gcaaggtctt ctgcttggta gtcttctggg
    25801 aatgttacga taacatcaac ggtttcgcca gctgagtgac ctaccaattg gtcttcgaaa
    25861 ccagggatga attgacctga accaagtcca agtgagaagt tttcaccttt tccaccgtca
    25921 aattcaacac cgtcgataga accaacgaag tcgatcacaa cagtgtcgcc gttttcagca
    25981 gcagcttcct tgataaccaa ttcagccagg ttgttgcgtt cgcgttcgat acgctcttca
    26041 acatcagcgt cagttacttc tttttctaca tcaactgata cttcaaggtt tttgtagtca
    26101 cccaatttta cttcaggttt tgtaacgact tcagcagcga taacccagtc ttgacctttt
    26161 tccattgaag ttacgtcaat ttttggttgg gcaaccactt caagaccagc ttcttttaca
    26221 gctgcttcat aagcgtttgg caaaagagcg ttcataacgt cttggtaaag tgattcttca
    26281 ccaaattttt tatcgaagat aggacgtgga aggtgacctt tacggaaacc tggaacatta
    26341 agagatttct tcactgactt gaagacacgg tccaattctg gtttgatttg gtcttgagag
    26401 atagtgaaag tcaagacacc acggtttgtt tctttgtttt caaatgatac agacattctg
    26461 tcatttctcc ttaaaatttt ttaaatacag tctattataa cattttctat aaataaaatc
    26521 tagactaatg cagccaatta tagacaacaa gcctttttcc taactaaaac actcataaag
    26581 tatagacaat tttagactac tttggatatc ttttggttag tcattttcca aaactaattt
    26641 atctaatttt tcagttatat agtagattga aactagaata gtacacctct acttctaaaa
    26701 catttttaga aatcgatttg actgtcctga tcgatttgtc ctgttcttgt ttcattttac
    26761 tatatagatc gcattcgaaa aaattcgttc caaaattgct tggttcgttc ttctcttgga
    26821 cgactaaaga attgatgggc attatttttt tcaacaattt tcccactctc cataaaaata
    26881 acatgatggg ctacatctct agcaaaacct atctcataaa gctgatcaaa aactcaatct
    26941 gaggagaaaa tccaataagg ctttccataa taaaggacat cctatcaaga tttttgaaca
    27001 cccgataggc tgcctttttc cgattttgaa gactttttgt ccagcttctt ttaccttata
    27061 aataacaaca aaaatcaaag acaagctaga aagattaccg cagataactc aaacagtgtt
    27121 ttgaggttgc agatggatgc taacctgatt tgaagagatt ttcgaaaaag attaaatata
    27181 ctctacaatt tgctcaatca attcttggtc gtctaaacct gtaacttgta taacaacatc
    27241 tttgactgat tgtttagcca acaattcacc taatcgaata ctttcttcat catttacatc
    27301 gcgatagtca aaggcatagc caactgtttt aagtaggttt ttatatgaca aactgagttc
    27361 tttcaattca cgtatcggcc ggatgaatcg ttcattatag cctaattttc ggattggagt
    27421 acgagctacg cgactaacct cgtccactat gaaaggattt tcaaaccgtt ctataatgac
    27481 tttgtgataa ttctccaatt cttttttatc aaagttccat ttggcaatca agagactccg
    27541 aatttcagct aatacagatt caatccgaga tttgatatta ggattttgaa gagcttccaa
    27601 aattgtcttg gcaccataat gcgcaccaat gtaagctgaa gttgcatgtc cagaattgac
    27661 tgaaaaaagt tttcgctcaa taaagggttc taaatcttct tcataatgca catcttttag
    27721 acgtaaatct ggatttttaa gacgcttggt ttccacgacc cattcattaa agggctcgac
    27781 cacaacaaaa agggaatctt cgtgactttg tgctggaaca atcctgtcta ctgcagcatt
    27841 tggaaaacct atgtagttat cagcaaatgt caaaccttcc ggacttaaat atttcttgac
    27901 ttcttgataa agaaattgag acccgccaat catattttca caggccataa catccaatac
    27961 ctgtgtattc cctgcaactc ggcgagcttc gattcctttg gctagaagtt cagcgataaa
    28021 agggagtata ttaggtccga ttgcagtagt aataatatcc gtcttttgaa tcgcttcaat
    28081 gacttgctca ggatgttctt tgctattaat gccagccaca ttagttactt ctatacgaga
    28141 ctgtcctttc tgtgcaattt caatttcata cttgcccttt tcatttagag catgaattat
    28201 ctgattattg acatccacaa aatcaatatg gaaaccattt ttaaatagaa tttcacctat
    28261 aaaaccacga ccgatattac cggcaccaaa atgaacagaa tgtttcattc aatttctcct
    28321 tttcctattt gagggacata tatactagat gacaaatgac gaaattcaat tattcaacag
    28381 catcaaataa gcgcaatact tcctcttttg actgagcatc tgctagttta agaacattat
    28441 ccacatctgc acagaagata gaaattttct gaataatttc taagtgttca ttaccaatac
    28501 cagcaatacc aaaaagaacc gttgccactt gagggttaga tacattccca aaatcaaccc
    28561 ctctagggac ttgaacgact gtaataccag acttgaggac atcctttttt gctgcatctg
    28621 ttccatgcgg tatggcgata aagttaccca tgtaaacaga tagctcttta tctcgctcaa
    28681 tcatggcttc aatatagtct tcattaacat atccaccctc ataaagaact tgcccacaat
    28741 aacaaatagc ttcctccttg ttagaaaatt gtttattaag cttaatcaaa tgtttttcaa
    28801 gtttcatatt agttctccaa tttcttaatt ttttcgttaa aaatagtatt tagcatctga
    28861 taaataatgg attgatttcc cgtcttgtaa atctctgtat aaagatgatt ttcaataatc
    28921 gactgactga tagctgtcat taaatctctc gcttcctcgc tagcttcttt agacattagc
    28981 attagcagac accttttgac ctcttcttcc tctcgtttca ttgacaatgc ggagataggt
    29041 agtttgagtt caaacatagt aaaactattt gttgttactt tgctagactg actatgtaaa
    29101 agcaccagac cagtattagg aatagccata ggactattct ggaagtgaga taacaatttt
    29161 cttgttaggt aatctctgtc actcacattc ttctgatatt ggatgatttg ttctaccgtg
    29221 tgctcaaatg attgattatt ctccaattga accaactcga attgactcaa aagctgacta
    29281 ctagatatta aataatcttg caagtcataa cttttctctg gagcgatagc atcacgcgcg
    29341 acaattgtac gatgtgcctg tacatactga agtcgttcct gtaattcaag caattctttg
    29401 acggttggaa aactagaaat tacatcgatt tcctgattag tcagcggctt ggtagataaa
    29461 atataatcat actgactgag atcaatactg tggtaatcta ctagagactg aatatctatc
    29521 aactctacaa aaggagcaac actcttaatt ttactgacta ataaatctct agtgacccga
    29581 cgttcatccg ttaaaagcaa aacacggact ggataaatct ctggactacg gcctaagcta
    29641 gagataaaat gtagggcaat catgccatac tcatactctg tatgaagata tttcggaaaa
    29701 atatcattca ctaaaagact gatgactgta taaagaaatt tattcctttc aactaaaatc
    29761 tggacagatt ctggcaaatt ttcaccctga aaaaggatag ggacgcctaa actgagccga
    29821 atatgatgga aaagaaaatt gaataaaacc ttgtccttaa aaaagtcaat cttggtatac
    29881 atggaaaccg tatcaatcag atttgaaata ttgtagaaaa attcaccatc aaatttctcc
    29941 gtaaagagcg gattgtcctg acgtttaatg attaattcat ccaagatgct cgcaaaatag
    30001 ataatttcct gaatactata aaattgtgca gtctgcttag agtaagcttg aaaaattttt
    30061 tgagaaattt ccaaagcctg cttactagta ttaggtgaat tttcaatgtt ttgctcctga
    30121 cctataagag ataacaagat cgcaaaaaac atcttcatcc tagcatccat atctggaaaa
    30181 cctgacagtt gcttattaac aatctgactg gccagcctag ttctatctgc ttctaaaata
    30241 tcaaagctcc caaaattacc ggttgaaaaa tctgctactg agatacagtt tgtcagtaaa
    30301 atagccaaaa atcttctctt accaactgaa tcaccagaaa tccgataacc tttttgtcgt
    30361 tcaattttca gatcaaagtc taaaagacgc ttatcaatat ctgaaatatc ctgaataata
    30421 gttacattac tgactttcgt gcactcttgc aatgcttcat tggtgacaaa accactctca
    30481 gtcagaaggc gataggtaat caactcttgt ctttcttggg gactatactc aactaacact
    30541 tcaagttctg tcggcaaatc atccaactct ccagtcaaaa tatagtattt cccatgcttc
    30601 gttatttcga ttccatattg ctccatgcta tctgtcaaat ctgataaagt tcgataaatt
    30661 gttctagatg aaacctgtaa gatttcagtc atatcttgca ttgaaagctt ccctacatgt
    30721 aggaaagcct tcaataattg ttcttctcgt ttggttaata gcattcgtaa tttagaaacc
    30781 tctagttcta tttgtacatt ctagcagcca ttttgtcata ttctggtgtt gttactaaac
    30841 tatccacaat aagaaattga gaattcggtg ctgcttgctg cacttctgcc tgtaaagaaa
    30901 tagttgttac aatcattatg tttttagaat taaattcacc taattctgaa attttggcag
    30961 tagaaactgg aatacgaata ttcttgtttc taaagatagc ccgaatcgtt tcacagccca
    31021 tagttgcagt tccctgtgct ttaccataag caactactac agcatcaata tggttgaggt
    31081 caatttcctg actatctact ggtgctgaag ttggtatatc tccttcaatt tctgctattg
    31141 gagaagctcc tgttaatgaa gctacaattt catcataacg aggggacgct aagaaattat
    31201 caacagaaac atgaatagca cttggactct tgtctttagc tcttggtgtc agttcttcct
    31261 gagtaacaat taatgttttt ggtgtatcaa gcaaatttga gattgcctga ttagatactg
    31321 gaatctctag acctgctttt ttaaccttat ctcgaagaat actagctccc atagcagagc
    31381 ttcccatacc agcatcgcag gcgaaaatga ttttttccac tgagtctgtc gaaacaactg
    31441 catcaacaga agttgatact aactgacctt tagactgagc cttagctgct tgggtagccg
    31501 cctgagcagc ttcgagcgaa tcctcagttg acttgtctgc atgaagaata agggctgcta
    31561 caaggaaaga aacaactgct gccactaaaa cacctaaaag aacatttaga tggggccaaa
    31621 caccttttgg cgccgtagcc ataatcgcaa taatagaacc tggtgaagct ggagatttaa
    31681 gaccagcgtc taagagttga aaagtaaaag ttccagagat acctcccgcc atagcagcta
    31741 aaaatagagt aggcttcatc ataacataag gaaagtaaat ttcatgaatc cctccgaaga
    31801 aatgaataac cattgccccc caagaagaag atttagcaga acctttaccg aatacagcat
    31861 aagctaatag aattcccagg cctggtccag gattagcttc caataggaag agaattgact
    31921 taccagcttg agctacctgt tctactccca gaggagtaaa aatgccatga ttgagggcat
    31981 tattgaggaa aaggacttta gccggttcga tgataatatt agccatagga aggaggcgag
    32041 cattgacaat agcctcaaca ccattcccaa cagctccagt aagagtcgat acgactggac
    32101 cgattgcgta gaaagccaaa agcaataatg caaaaccaac gagaccagct gagaagttat
    32161 taactaacat ttcaaatccg ggacgaattt tttcctggaa cttctcatca aatttcttga
    32221 tagtccatcc tcccagtggg cccattacca tagctccgat aaacatagga acactagaac
    32281 ctgtgattgc accaacagta gcaatagctc ctacaacggc accacgttgg ccatggatca
    32341 tatatccacc tgtgtaacca atcaggattg gcaataaata cgttaacata ggaccaacaa
    32401 cagtagctaa ctgttcattt ggcagatagc catcagcgat aaagagggca gtcaatactc
    32461 cccaagcaat aaatgctcca atattgggca taaccatatt tgaaagcgat gtccctagtt
    32521 tttgaaccct gactttcaat gatacttttt cttccattag atcatcctcc ttttcttaaa
    32581 actagtatat acaaagttaa aaacctttaa aactaaagtt ttgtcacaga ttttgtgtca
    32641 aaacattact tttgacgagg ctgggcaaaa aggcttaaaa attataaaac gcatcatatc
    32701 aggtgtacat gaactacacc ccaaaagtta gacagaaaaa atctaacttt tggggtgttt
    32761 ttattatgaa attaacttat gatgataaag ttcagatcta tgaacttaga aaacaaggat
    32821 atatcttaga gaagctttca aataaatttg ggataaataa ttctaatctt aggta
//
LOCUS       DAVLZS010000022        31975 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLZS010000022 DAVLZS010000000
VERSION     DAVLZS010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31975
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.022"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            649..1925
                     /gene="ltrA"
                     /locus_tag="VYO88_001088"
                     /pseudo
     CDS             649..1925
                     /gene="ltrA"
                     /locus_tag="VYO88_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            2385..3095
                     /locus_tag="VYO88_001089"
     CDS             2385..3095
                     /locus_tag="VYO88_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1719200.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSSLSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLLYQQI
                     YWKFFQIRFGFLPLYLFL"
     gene            3041..3562
                     /locus_tag="VYO88_001090"
     CDS             3041..3562
                     /locus_tag="VYO88_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1719201.1"
                     /translation="MEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTVYSIGIIISG
                     LIAFRLSEKFLAAKWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVP
                     ESVFLQETVEENHLVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMI
                     EAILIYIRRDYFK"
     gene            3876..4007
                     /locus_tag="VYO88_001091"
     CDS             3876..4007
                     /locus_tag="VYO88_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1719202.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            4028..5578
                     /gene="dltA"
                     /locus_tag="VYO88_001092"
     CDS             4028..5578
                     /gene="dltA"
                     /locus_tag="VYO88_001092"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1719203.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            5575..6819
                     /gene="dltB"
                     /locus_tag="VYO88_001093"
     CDS             5575..6819
                     /gene="dltB"
                     /locus_tag="VYO88_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1719204.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            6833..7072
                     /gene="dltC"
                     /locus_tag="VYO88_001094"
     CDS             6833..7072
                     /gene="dltC"
                     /locus_tag="VYO88_001094"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1719205.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            7065..8333
                     /gene="dltD"
                     /locus_tag="VYO88_001095"
     CDS             7065..8333
                     /gene="dltD"
                     /locus_tag="VYO88_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1719206.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            8488..8928
                     /gene="adcR"
                     /locus_tag="VYO88_001096"
     CDS             8488..8928
                     /gene="adcR"
                     /locus_tag="VYO88_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1719207.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            8928..9632
                     /locus_tag="VYO88_001097"
     CDS             8928..9632
                     /locus_tag="VYO88_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1719208.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNTHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            9625..10431
                     /locus_tag="VYO88_001098"
     CDS             9625..10431
                     /locus_tag="VYO88_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1719209.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            10441..11946
                     /gene="adcA"
                     /locus_tag="VYO88_001099"
     CDS             10441..11946
                     /gene="adcA"
                     /locus_tag="VYO88_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1719210.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQETLFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(13075..13848)
                     /locus_tag="VYO88_001100"
     CDS             complement(13075..13848)
                     /locus_tag="VYO88_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1719211.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPNHKLLDAVELFDGEWVSDIQ"
     gene            14024..15427
                     /locus_tag="VYO88_001101"
     CDS             14024..15427
                     /locus_tag="VYO88_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV1719212.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEATAVGNIVVQLLSQGKINEDTGLK
                     DIMTNIADTQYYYPQLS"
     gene            15456..16748
                     /locus_tag="VYO88_001102"
     CDS             15456..16748
                     /locus_tag="VYO88_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1719213.1"
                     /translation="MNKKSLLKCAVIGLVATFGLAACGTSKDASGGSSSGKEVLEFYH
                     GYHHSEDEWPVAKTMRDLYDKFAEEHKDSGVEFKPTPVNGDLKDIMNNKVASGEFPDV
                     IDLAGNAVSLAAIEQKLVLDLKPYIDSNKLEKNVGLNYKQNQKDGKIYTVHEQLFTMG
                     LWYNKDIFAKAGAKTPEQWNTWDDFTQAMASIRKQDGVYAFGAGEPSIRLFNTVLGTT
                     ENGRKLLDKPLTKEGIESKEFADALKMVMKEIQANGSKNAGGDANAYSKDFQEGKSAV
                     FFNGVWASGEMSKNPSLAPGIYPAGVAISSSGGGITISSKMSEAKQKLALEFLKYMTS
                     DDVQKVIFEKVGANPSNENVNVKELSEKSSEATTKILGQAITQVKNAKAVVPTVSDVW
                     GGDVHTAIINALTESAAENVDVDQKVKSTQDVLKSLIG"
     gene            16835..17764
                     /locus_tag="VYO88_001103"
     CDS             16835..17764
                     /locus_tag="VYO88_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1719214.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIFCINILFRERKRLKGGK"
     gene            17767..18606
                     /locus_tag="VYO88_001104"
     CDS             17767..18606
                     /locus_tag="VYO88_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1719215.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPTDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            18603..19922
                     /locus_tag="VYO88_001105"
     CDS             18603..19922
                     /locus_tag="VYO88_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1719216.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNENTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            19928..21799
                     /locus_tag="VYO88_001106"
     CDS             19928..21799
                     /locus_tag="VYO88_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
                     /protein_id="HEV1719217.1"
                     /translation="MKIENKNVRRNFFWGDGRFYTTDIVNKRAGVMIKNVSKEEFTIT
                     LENGIRLSSNHFSAIVREEGDMRIQVSFVCPSIRLRLIFESRDDVLSKQLVLESSTEV
                     IKSVEVESFEFETEDNIFYPKRQDCIKEMANFSGYYVELGQPVYANSLFLGMEFPMSE
                     NKVDGRHYVSRYYLGTVVNQEKSLWSCIIGGACSYKKEEIQEAFFEYVEGIAQPSYFR
                     KQYNSWYDHMTDITEEGILKSFSEIRDGFENHGVHLDAYVVDDGWTNYQSVWEFNHKF
                     PNGLRNIKHLVNGFGSSLGLWIGPRGGYNGTEIIMSDWLEAHPELNIGSKNLISNDVN
                     VADFNYLNQMKKKMLEYQKEFDISYWKIDGWLLQPDKPDKSGPHGMYTMTAVYEFLIQ
                     LLIDLRKERGGKDCWLNLTSYVNPSPWFLQWVNSLWIQISQDVGFTENAGNDINRMIT
                     YRDSQYQEFLEKREIQLPMWSLYNHEPIYAVSTNTWYMDHQMFASIPDFEAYLLFIST
                     RGNAFWEFHYSFDMFDEERWKANARAVKWIEENYQTLKYSKKIGGSPEKFEIYGYKCH
                     NQKTSTEILSLRNPAQIKQKIKIENLSIENFTRVIGDFTIQEDEIELAPYSIVILKK"
     gene            21821..24037
                     /locus_tag="VYO88_001107"
     CDS             21821..24037
                     /locus_tag="VYO88_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1719218.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCAETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLLQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSGFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            24048..27064
                     /locus_tag="VYO88_001108"
                     /pseudo
     CDS             24048..27064
                     /locus_tag="VYO88_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
     gene            27079..27807
                     /locus_tag="VYO88_001109"
     CDS             27079..27807
                     /locus_tag="VYO88_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEV1719219.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            27820..29586
                     /locus_tag="VYO88_001110"
     CDS             27820..29586
                     /locus_tag="VYO88_001110"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1719220.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            29732..30883
                     /locus_tag="VYO88_001111"
     CDS             29732..30883
                     /locus_tag="VYO88_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1719221.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMAINGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMISKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVANGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            31028..31912
                     /locus_tag="VYO88_001112"
     CDS             31028..31912
                     /locus_tag="VYO88_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1719222.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
BASE COUNT        10165 a         5195 c         6737 g         9878 t
ORIGIN      
        1 cctcggtggg cacctgctac cggtgaaccc aatagcgatt cccaagcctg actatcgtga
       61 ggtagcaggg agaggaaggg atagcgaaat cgtggctcta cgaacaggaa cgtgatagta
      121 aggcgtatat agcggataag gaggcttcaa actctaaagt ccaaaaaggt agtcgtaacc
      181 tatatgtgta aatcatgaga gtaattgaat tcggactaag gtttgtgtga aaaagataaa
      241 tctttctaga gtctaaagac tctgcgtcag atttcctatt ttcactgtaa ccttttaacg
      301 tcctcatatc ttgtataaac gaggaaagat gtacgactta tcccgtgagg tttcatgagc
      361 gctgaaagcg tagtaacaac gaatcatgag aagtcagccg agcccatagt agtgaggaaa
      421 cttctgtagt ggaagtggag cgaaggggtg aatactcaaa cagtctgggg agagactgtt
      481 tgaggtctgt cgctagaaag agaaaacgac agatcgaagt aatcctactt cacttgtgtc
      541 tgtaaaatga gtggtctgat agaactggac tttgacacgt aatgactaga tgaaggttca
      601 ccaatataag atgtccctca ggcaccaaaa caagaaagga atacgcacat gtcaaaactg
      661 ctagataaga tattatcacg cgaaaatatg ctggaagcct acaatcaagt aaaatccaat
      721 aaaggctcag ctgggattga tggaatgact atcgaagaga tggataatta tctcagacaa
      781 aactggcgct tgactaagga actgataaaa cagagaaaat ataagcctca accagttctt
      841 aaagttgaga tacctaaacc agacggaggc atccgtcaac taggaatttc aacagttatg
      901 gatagaatga ttcaacaggc cattgtccaa gtcatgagcc ccatttgtga accccatttc
      961 tcagatacga gttatggttt cagaccaaat aggtcatgtg aaaaagccat catgaagctc
     1021 ttagaatact taaatgacgg ctatgagtgg atagtggata tagacctaga gaaatttttc
     1081 gatacagttc ctcaagatag attgatgtcc ttagtacata acattatcga agacggagat
     1141 acggaatcct tgattcgtaa gtatcttcat tcaggtgtta tcattaatgg tcaacgttat
     1201 aaaacactag ttggtacacc acagggagga aatttatctc ctctcttatc caatatcatg
     1261 cttaatgaat tggacaagga attagaaaag aggggacttc gatttgtgcg ctacgcagat
     1321 gattgtgtga tacggtcgga agcgaggcag ccgctaagcg tgtgatgtat tcagtcagtc
     1381 gttttattga gaaacggcta ggtttgaaag taaacatgac caagactaag attaccagac
     1441 caagagagtt gaaatatcta ggttttgggt tctggaaatc atcagatggt tggaaaagtc
     1501 gtccacatca agatagtgtt cggagattta agcttaaatt gaagaaacta acacagagga
     1561 aatggagtat agacctaaca agacgtattg agcaactgaa tttgtctatt cgaggatgga
     1621 taaactattt ctcattggga aatatgaaaa gtatagtcgc cagcatagat gagcgcttgc
     1681 gtactcgcct acgagtgatt atctggaagc aatggaagaa gaaatcgaga cgattatggg
     1741 gattgcttaa gttaggagtt cctaaatgga tagcagataa ggtatctggc tggggcgacc
     1801 attatcaatt agtagctcag aagtcggtac ttaaacgtgc tatatcaaaa ccagtcctgg
     1861 aaaaacgtgg actggtttcg tgtttggatt attaccttga acgacatgcg ttaaaagtta
     1921 gttgaaccgc cgtatgccga acggcacgta cggtggtgtg agaggggcta gagattatcc
     1981 cctactcgat taactcccct gaaatttatt ttaattatgc aaatttcacg tatttttgat
     2041 gctgagacga cgatcctggg aacttttcag atattttttt gactatctaa atctatcatt
     2101 agaaaagctt agagcgccaa aggatttgag cgtttttctg atttttaaga ctttttccag
     2161 tctctttttc gattgaagat gtaattattc tactaactaa ctaactaact tcttagtact
     2221 agccaacaac gataatcata attcctccta aaattaggaa taataaaggc aatagttttt
     2281 gttttttcat gtaaaaaacc tcacttttgt tttctgctat tttatgctaa aatattaaaa
     2341 atcaaattta attccaaagt ttgtaactaa agggggagcg ctacatgtct aattcatttg
     2401 tcaagttgtt agtctctcaa ttatttgcaa atttagcaga tattttcttt agagtaacaa
     2461 tcattgctaa catatacatt atttcaaaat cagtaattgc cacatcacta gttcctatct
     2521 taataggaat atcctctttt gttgcgagtc ttttagttcc gttggttact aaaaggttag
     2581 cgctaaatag ggttttatct ttatctcaat ttggaaagac tatattattg gcgatactgg
     2641 taggaatgtt taccgtaatg caatccgtag cgcctttggt gacctatcta tttgttgttg
     2701 caatttccat actagatggt tttgcagcac ccgtttccta tgctattgtg ccacgctatg
     2761 cgaccgattt gggtaaggct aattcatcct tatcaatgac tggtgaagct gttcaattga
     2821 taggttgggg attaggtgga ctcttgtttg caacaattgg tctgttacct accacgttta
     2881 tcattttagt cttgtatatc atttctagct ttctgatgtt atttcttcct aacgctgaag
     2941 tggaggtgtt agagtcagaa actaatcttg aaattttgct caaaggttgg aagttagttg
     3001 ctagaaatcc tagattaaga cttttgtatc agcaaattta ttggaaattt tttcaaatac
     3061 gatttgggtt tcttccatta tacttgtttt tgtaacggag ttattaaata aaacggaaag
     3121 ttactgggga tattctaata cagtatactc tattggtatt ataattagtg gcttaattgc
     3181 ttttaggcta tctgaaaagt tccttgctgc taaatgggaa agtattcttt ttcctcttgt
     3241 agctatggca atagtgacac tgactattct atattttcca aacgcacaga tgtttttatt
     3301 attttcagct ttagttggta tgttatcgca actaaaagaa gttcctgaaa gtgtatttct
     3361 tcaggaaaca gtagaggaaa atcatttagt taatgtctat tccgttcttg aagtgatttc
     3421 tacattagca ttttcagtat ttgttttgct aatgagctat attactgaga gttttggtat
     3481 tagcatcagt ttttggctat cagccatttg tctgatgata gaagctattt taatttatat
     3541 cagacgagat tattttaaat gagagagtgg ttaaaaagtc tttaaaaatc agaaaagcgc
     3601 atagtatcag gtgttgaaaa aacttgatat tgtgtgtttt attatgggaa gatttacttc
     3661 attgtctcct gaaatggagt tttgaagcag gatcactcta tttgaaaata tacatagaaa
     3721 aaccgcataa tccttaaaat aagctgaaat ctattggaaa catacggtaa acaattgaaa
     3781 agatactata taaagtggta caatggtaga aaaataagct agtaagaatc actcttattt
     3841 tagcgaaaaa ttacagaaat gaatggtttt tcttgatgaa acagagaaaa gaattgtacc
     3901 tctttcttgg tcggacagcc ttgtattttc ttatctttct agggctgctt tacttcttta
     3961 gctatcttgg tcagggtcaa ggaagcttta tctataatga attttaactt gaaggagaat
     4021 ccctattgtg tcaaataaac caatagcaga tatgattgaa accattgagc attttgctca
     4081 gacacagcct agctatcctg tctataatgt tttggggcag gaacacactt atggcgattt
     4141 aaaggctgat tcggatagtt tggctgcagt cattgaccaa ctaggcttgc ctgaaaagtc
     4201 tcctgtggtt gtttttggtg gccaagaata tgaaatgttg gcaacctttg tagcgctgac
     4261 taagtcaggt catgcctaca ttccaattga tagccattcg gccttggagc gagtttcagc
     4321 tattttagaa gtagcagagc caagcttgat tattgccatt tcagcctttc ccttggagca
     4381 ggtttctaca ccaatgataa atctagctca ggttcaagaa gcctttgccc aagggaataa
     4441 ctatgaaatc acgcatccag tcaagggaga tgataattac tacattatct ttacttctgg
     4501 tacgactggt aagcctaagg gagtgcagat ttcacatgat aatctcctca gctttacaaa
     4561 ctggatgatt acggataagg aatttgcgac accgagtcgt ccgcaaatgc tggcacagcc
     4621 accttattct tttgacttgt ctgtcatgta ttgggcaccg accttggcac ttggtggtac
     4681 gcttttcact cttccttcag tcatcactca ggactttaag caactctttg cggctatctt
     4741 ttcattgcca atcgctatct ggacatcaac accatccttt gcagatatgg ccatgttgtc
     4801 tgaatacttc aacagtgaga aaatgcctgg aatcacgcat ttctactttg atggtgaaga
     4861 attgacggtc aaaacagctc aaaaactgcg cgagcgtttc ccaaatgccc gtatcatcaa
     4921 tgcttacggc ccaacagaag cgacagtagc tctgtcagca gttgccgtga cagacgagat
     4981 gttagcgact ctcaaacgcc taccaatcgg ctataccaag gctgattctc caacctttat
     5041 cattgacgag gaaggaaata aactgccaaa tggcgaacag ggagaaatca ttgtttctgg
     5101 gccagctgtt tcaaaaggtt atatgaacaa tcctgaaaaa acagcagaag ccttctttga
     5161 gtttgaaggt ctgccagcct atcacacagg cgatgtggga accatgacag atgagggctt
     5221 gcttctctac ggcggacgca tggacttcca gattaagttc aacggttacc gcattgagtt
     5281 agaagatgtc tctcaaaacc tcaacaagtc tcgctttatc gaatctgctg tcgcagtacc
     5341 gcgctataac aaggaccaca aggtacaaaa tctattggct tatgtcatct taaaagacag
     5401 tgttcgtgag cagtttgagc gagatatcga tattaccaag gccatcaagg aagacctgac
     5461 agacatcatg atgtcctaca tgatgccatc taaattcctt taccgagaca gtttgccact
     5521 gactccaaat ggaaagattg acatcaaagg attgattaac gaggtgaata agagatgatg
     5581 gagttttttc aacagcttcc tcatttagag ccatatggca atcctcagta ttttgtttat
     5641 gtgattgctg caaccttgcc catctttata ggcctctttt tcaagaaacg ctttgcctgg
     5701 tatgaagtgt tggtaagtct cttctttatt gtcaccatgt tggtgggtgg aaagaccaat
     5761 caactagctg ccttgggtat ttacctttgc tgggaaatat tgctcctgct tttctacaag
     5821 cattatcgaa aaagcaagga tggcaagtgg gtcttctact tagttagttt tctgtcccta
     5881 cttccgatta tctttgtcaa ggtgcaacca gctatcaatg gaacgcagtc tttgcttggg
     5941 ttcttgggaa tttcttacct gacctttcgt tcggttggga ttatcatcga gctgagagat
     6001 ggagtgatta aggattttac cctctgggaa ttcctccgtt tccttctctt catgccaact
     6061 ttctcgagtg gtccaatcga tcgctttaag cgatttaatg aaaattatca ggctattcct
     6121 gagcgagatg agttgatgga tatgctggat gaatctgtcc gctatatcat gtggggcttt
     6181 ttgtataagt ttatcctagc tcatgtttta ggagagacct tactacctcc tctgaagaat
     6241 ttagccttgc agtcaggtgg cttctttaat ctctatgcct tggcagttat gtatactttt
     6301 ggtctggagc tcttctttga ctttgcaggt tattctatgt ttgctttggc catctcaaac
     6361 ttgatgggaa tccgtagccc tatcaacttt aacaagccct ttttatcaag ggatttaaag
     6421 gagttttgga atcgctggca tatgagtctg tccttctggt tccgtgactt tgtctttatg
     6481 cgaatggtga tggtgttaac cagaaagaaa gtctttaaaa atcgtaatgt aacctcaagc
     6541 atggcctaca ttgtaaatat gctgattatg ggattttggc atggtgtgac ctggtactat
     6601 atcgcctatg gactctttca tggactaggc ttggtcatca atgatgcctg ggttcgcaag
     6661 aaaaaaacgc tcaataagga acggaaaaaa gcagggaagg ctgccctacc tgagaatcgc
     6721 tggattcagt tgcttggcat ggttgtcact ttccatgttg tcatgttgtc attcttaatc
     6781 ttttctggat tcttgaataa tctatggttt aaaaaataaa aggaaataaa atatggatat
     6841 caaatcagaa gttattgaaa ttattgatga gttgtttatg gaagatgttt ctgacatgat
     6901 ggatgaagat ctttttgatg caggtgtctt ggatagtatg ggaacggttg agttgattgt
     6961 ggagattgag aaccgttttg acattcgtgt ccctgtaaca gagtttggtc gtgacgactg
     7021 gaatacagct aataaaatca tagctggtat tgtggagcta caaaatgctt aaacgcttat
     7081 ggatgatctt cggaccggtc ttgatcgctg gtttgttggt ttttctgctc attttctttt
     7141 atcctactga gatgcatcat aatctaggag ctgaaaagcg ttcagcagtg gctactacta
     7201 tcgatagttt taaggagcga agtcaaaaag tcagagcact atctgatcca aatgtgcgtt
     7261 ttgttccctt ctttggctct agtgaatggc ttcgttttga cggtgctcat cctgcggtat
     7321 tagctgagaa atacaatcgt tcctaccgtc cttatctttt aggacagggg ggagctgcat
     7381 cgcttaacca atattttgga atgcaacaga tgttaccaca gctggagaat aaacaagttg
     7441 tgtatgttat ctcacctcag tggttcagta aaaatggcta tgatccagca gccttccagc
     7501 agtattttaa tggagaccag ttgactagtt ttctgaaaca tcaatctggg gatcaggcta
     7561 gtcaatatgc agcgactcgc ttactgcaac agttcccaaa cgtagctatg aaggacctgg
     7621 ttcagaagtt ggcaagtaaa ggagaattgt cgacagcaga caatgaaatg attgaattat
     7681 tggctcgttt taatgaacgc caagcctcct tttttggtca gttttcggtt agaggctatg
     7741 ttaactacga taagcatgta gctaagtatt taaaaatctt gccagaccag ttttcttatc
     7801 aagcaataga agatgttgtc aaagcagatg ctgaaaaaaa tacttccaat aatgagatgg
     7861 gaatggaaaa ttatttctat aatgagcaga tcaagaagga tttgaagaaa ttaaaggatt
     7921 ctcagaaaag ctttacctat ctcaagtcgc cagagtataa tgacttgcag ttggttttaa
     7981 cacagttttc taaatctaag gtaaacccga tttttatcat tccacctgtt aataaaaaat
     8041 ggatggacta tgctggtcta cgagaggata tgtaccaaca aacggtgcag aagattcgct
     8101 accagttaga aagtcaaggt tttaccaata tagcagattt ttctaaggac ggcggggagc
     8161 ctttctttat gaaagacacc attcaccttg gttggttggg ttggttggct tttgacaagg
     8221 cagttgatcc tttcctatcc aatcccacac cagctccgac ttaccatctg aatgagcgct
     8281 ttttcagcaa agattgggcg acttatgatg gagatgtcaa agaatttcaa tagataatat
     8341 aatatagaag agttcaagaa tgaaactagt tttcacgttt tttcttgact ctttttttgc
     8401 ttgtgatata attaactggt aaacaaaatg tcaaagaata gtatttttct cttaaaaaag
     8461 agaagtctaa aaggaaagga gtcagatatg agacagctag caaaggatat caatgctttt
     8521 ttgaatgagg tgattttgca ggcggaaaat cagcatgaaa tcctaatagg tcattgcact
     8581 agcgaggtgg ccctgaccaa tactcaggag catatcctta tgctcttgtc agaggaatct
     8641 ttaacaaatt cagaattggc ccgtcgtctc aatgtcagtc aggcggcagt taccaaggcc
     8701 attaagtctt tggtcaagga agggatgttg gaaacatcta aagattctaa agatgcgcgt
     8761 gtgatttttt atcagttgac tgacttggct cgtccaatcg ctgaggagca ccaccatcac
     8821 catgagcata cacttttaac ctatgaacaa gtggcgactc agtttactcc aaatgaacaa
     8881 aaagtgattc agcggttttt gactgcttta gtaggagaaa tcaaataatg agatatatta
     8941 cggtagagga tttgtccttc tattatgata aggagcctgt tcttgaacat atcaattata
     9001 gtgttgatag tggggaattt gttaccttga ctggggaaaa tggagcggct aagacgacgc
     9061 tcatcaaggc cagtcttgga attctgcaac cacgcattgg aaaggtggct atttcaaaga
     9121 caaatacgca aggtaagaaa ttgagaatag cctatcttcc tcaacaaatt gccagtttta
     9181 atgctggttt tccaagtacg gtctatgaat ttgtcaagtc gggtcgctat ccgagaaaag
     9241 gctggttccg tcgtttgaat actcatgatg aggagcatat caaggctagt ctggactcag
     9301 ttggcatgtg ggaacatcga gacaaacgct tggggtctct atctggggga caaaagcagc
     9361 gagcggtaat tgcgcgtatg tttgcttctg accctgatgt gtttatccta gacgagccga
     9421 caacggggat ggatgcagga agtaaaaatg aattttacga actcatgcat cacagcgccc
     9481 atcatcatgg caaggctgtt ttgatgatta cccatgaccc tgaagaagtt aaggattatg
     9541 cggatcgcaa tattcatcta gtccgtaacc aagactcgcc atggcgttgt ttcaatgttc
     9601 atgagaatgg ccaggaggtg ggccatgctt agtttattat cttacgactt tatacaacgc
     9661 gcctttttgg cggttattgc tatgagtctt ttctcaccgg tattgggaac cttcctcatc
     9721 ttgcgtcgtc agagtttgat gagtgatacc cttagccacg tctcactttc aggtgtagcc
     9781 tttggtctgg ttttggggat ttctccaact gtttctacta ttgccattgt cttgattgcg
     9841 gcggtctttc tggagtatct ccgtacggtt tacaagagct ttatggaaat cgggacagct
     9901 atcctcatgt caacaggtct ggctgtttct ctgattgtca tgagcaaggg taaaagctcg
     9961 agttcaatga gtttggacca atatctcttt ggttcgatcg tgactatcag tgaagaacag
    10021 gtcatttccc tctttgtcat tgcggcggtt gttttgattt tgacctttct ctttcttcgt
    10081 cctatgtata tcttaacttt tgacgaagat acggcctttg tggatggctt gccagttcgt
    10141 accatgtcca ttctttttaa catggtgaca ggggtggcta ttgcccttat gattcctgca
    10201 gcaggagctc ttctggtatc gaccattatg gtcttgccag ctagtattgc cctgcgtctg
    10261 gggaaaaact ttaaatcggt tatgctgctt gccagtgcga ttggcttttt gggaatggta
    10321 gcaggacttt acatttccta ctatgcagaa acacctgcaa gtgcaagtat taccattatt
    10381 tttgtaactg tctttatact aatcagttta gtaagacgtt ttatcaaata ggagacgaac
    10441 gtgaaaaaaa ttagcttatt actagccagt ctatgtgcct tgtttttagt ggcttgttcc
    10501 aatcaaaaac aggcagatgg taaactcaat atcgtgacaa ccttttaccc tgtctatgaa
    10561 tttaccaagc aagtcgcagg agatacggct aatgtagaac tcctaatcgg tgctgggaca
    10621 gaacctcatg aatacgaacc atctgccaag gcagttgcca aaatccaaga tgcagatacc
    10681 ttcgtttatg aaaatgaaaa catggaaaca tgggtaccta aattgctaga taccttggat
    10741 aagaaaaaag tgaaaaccat caaggcgaca ggcgatatgt tgctcttgcc aggtggcgag
    10801 gaagaagagg gagaccatga ccatggagaa gaaggtcatc accatgagtt tgacccccat
    10861 gtttggttat caccagttcg tgccattaaa ctagtagagc acatccgcga cagcttgtca
    10921 gcagattatc ctgataaaaa agagaccttt gagaagaatg cagctgccta tatcgaaaaa
    10981 ttgcaagcct tggataaggc ttacgcagaa ggcttgtctc aagcaaaaca aaagagcttt
    11041 gtgactcaac acgcagcctt taactatctt gccttggact atggactcaa acaagtcgca
    11101 atctcaggcc tttctccaga tgcagagcca tcagctgctc gcttggcaga attgacagag
    11161 tatgtcaaga aaaataaaat cgcctatatc tattttgaag aaaatgcctc acaagccctt
    11221 gctaacacac tttcaaaaga agcaggtgtc aaaactgatg tcctcaatcc tttagaaagt
    11281 ctgacagaag aggacaccaa ggctggagaa aactacattt ccgtgatgga gaaaaacctc
    11341 aaggctttga aacaaacaac agaccaagaa ggcccagcaa tcgaacctga aaaggcagag
    11401 gataccaaga cagtccaaaa tggttacttc gaggatgcag ctgtcaagga ccgcaccttg
    11461 agtgactatg caggtaactg gcaatcagtt tatcctttcc ttgaagacgg cacgtttgac
    11521 caagtctttg actacaaggc taagttgact ggtaagatga cccaggctga gtacaaggct
    11581 tactatacaa aaggctatca gacagatgtg actaagatta acattactga taatactatg
    11641 gaatttgttc aaggtggaca aagcaagaaa tacacttaca agtatgtcgg taagaaaatt
    11701 ttgacttaca agaaaggcaa tcgtggcgtg cgtttcctct ttgaagccac agatgctgac
    11761 gctggacaat tcaagtatgt tcagtttagt gaccacaata tcgccccagt taaggcagaa
    11821 catttccata tcttttttgg aggtacaagc caagaaactc tatttgaaga aatggataat
    11881 tggccaacct actacccaga taacctatct ggccaagaaa tcgctcaaga aatgttggcg
    11941 cattaatgag aaatcgacta gttcataaga gctagtcggt ttttgggtac tagatggcta
    12001 acttcattat agacttttca gaactaagga actttaaaaa aataaataaa actcttgaaa
    12061 tatctggact tatatgctag aatgtagtta gtgtataagg ttcattagaa caccaaagcc
    12121 cctaactagt gccatagtta agggcttttt tgacgtatct tagcgattta acgggtgttt
    12181 ataggctagt cagtcggtct acttcttacc atctagccat ttgcagacga aatacaagat
    12241 aattccagct ataacatctg ctataatagt aagagcaagc tctggtataa ggctcattag
    12301 tttcacctcc tctcacgaac cgtaaggaag gtaatcggta accgatgaca aaagtattat
    12361 accacactaa atttagatca tcaacctcac ttaatgcttg aactattgta gattatatgc
    12421 taaaatgtag ttaattgata aggttcatta gaacaccaaa gcccctaact atggccgtag
    12481 ttaagggctt ttttgacgta tcttagcgat ttaacgggtg tttataggct agtcactcgg
    12541 tctactcctt actatctagc catctgcaga cgaaatacaa gataattcca gctataacat
    12601 ccgctataat agtaagagcg agctctatga taaggctcat tagtttcacc tcctctcacg
    12661 aacccatagg aacgtaatcg gtaaccgatg acaaaaatag tataccacaa tacatttaga
    12721 tcatcaaggt cacttaattc ttgaaatata gggtctaggc gacaaagtct ttaaaatcag
    12781 aaaaacgcat aatatcaggt gtgcaaaaac ttgatactat gcgttttatt gtgggaaggt
    12841 ttactccatt ttctcctgaa attgagtttt tgtccagcct ctgtttttag aattgctaag
    12901 aaaataatgt catgtggtga atatttgtaa atcagtcagc agacagaacg aatactcttc
    12961 gaaaatctct tcacatcatg tcagcttcgt cttgccgtgt ccatggggga cttgacttca
    13021 tcagttttca aatctgtact ttgagcaagc tgagactagc ttcctatttg attttcattg
    13081 aatatcagaa acccattctc catcaaataa ttcgactgcg tctaataatt tgtgatttgg
    13141 caaggtgtca gaaataaagg ttgtgtattt ggagagggga ttaattttaa aaaatccagt
    13201 cttgtaaaat ttagaactat caatcagtaa gatggtttca tgggctttgt caataatatt
    13261 cttttttgaa atagcttggc tgagagaagc ttcataaaca tattggtcat caatacctct
    13321 tgctgaacaa aatgctaaat cgatattaaa atgatctaat aaagaatttt ccttatcata
    13381 gttgaccacg gaacaggatt gatgtttgac ctcgccagat gtgataaaga ttttggagct
    13441 atctttaaca gtttcagata gggtttgtgc agtatgtaaa ccatttgtaa aaataatcaa
    13501 attatcaagt tcagaaagat agggacaaag ttcgtagaca gtcgtactgg aatccagata
    13561 aatacacatg cctgaccgaa taaagtcttt agcgagacta gcgattagtc ttttttgcct
    13621 agtactttct ccttcccgta tttgatgaga aagttcaatt gtgttcatag aggacagggt
    13681 cacgtatccg tgctttcttt tgataagacc ttgattttct aagaaaatta aatcacgacg
    13741 taaggtactt gtgctggaga aagtgatttc tgccagctct tttacggcaa ttcttttttt
    13801 ctttttgatg atttcaatca attcaagtac acgttcatct tttatcataa gctcctccta
    13861 atttatcatt tcaactatat tatagcacaa attggaggaa tgtgaattat ttttatgaat
    13921 attgggttaa catttgaaca ttattcaagt aagcgttcac atattgaaaa aataaaacgt
    13981 ggggattata ataaagttaa tcaaggacga agagagaaga aaaatggaag cggttttagc
    14041 aatagattta ggtgcgactt ctggaagagc aatcgttggt tacctttctg aaaataaact
    14101 agtaatggaa gaaataaatc gcttttctaa tctacctatt agagtaaaag ggcatttatc
    14161 ttgggatgtt gactttctac tagctaaaat tcttgaaagt atccgcttgg ctaatactag
    14221 ttacaagatt ttatctatcg gtattgacac atggggagtt gattttggac tgattgataa
    14281 tgaaggtaag ctgttatcac aacctgttca ttatcgtgat gaaagaacaa agggagtgtt
    14341 aaaggaaata tctgaaatga ctgaattaga aaaactgtat tcagagacag gaaatcagat
    14401 tatggagata aataccttgt ttcaactctt taaggcacgt caagaatctc ctgactcttt
    14461 ctataagacc aataagattc ttttaatgcc agatttgttt aattatctct tgacaggtaa
    14521 gtttgctaca gaaaaaagca ttgcttcaac aactcaatta tttgatccta ggagtcaaaa
    14581 ctggaatcag aatatcttaa aactatttga attggattca tctttacttc ctgagattgt
    14641 ttcagaggga aatgttcttg gaaggataaa aaaggagtat ggtttaggcg atattcctgt
    14701 tgtgaatgtt tgtagtcatg atacagcaag tgcgattgtc tcagtaccta agacagaagg
    14761 tagtttattt atttcatcag gtacttggtc tttggttgga gtggaactta cttcaccgat
    14821 tcttactacc gaatccttca gttatggatt tacaaatgaa gtcggtaaag atggagagat
    14881 tacatttctg aagaattgta cagggttgtg gatcatagag gaactaagac gttcatttga
    14941 acgaagaggg aaagcctatt cttttgatga tattaggaca atggtggaga aagaaaaaga
    15001 aaatcttcct ctgattgata ctgaatcaac agaatttgca acagaatctg atatgcacaa
    15061 gactttgaca gaatatctag cttatcatca tgaaactaga gagtggacag atggacaact
    15121 atttaagatt gtttatgaaa gcctagctga aacgtatagg aaagcgatag agttattaga
    15181 agaactaact cataaggttt ataagaggat atatgtgatt ggaggaggtg ctagagccag
    15241 ttattttaac caaatgattg ctgatagaac tggtaaagaa gttcttacag gttcaactga
    15301 ggctacagct gtggggaata ttgttgtgca gctattgagt caaggtaaaa taaacgagga
    15361 tacagggtta aaggatatta tgacaaatat tgctgataca caatattatt atcctcagct
    15421 atcataaaca aaaataaaaa aacggaggtt ttgtcatgaa caaaaaaagt cttttgaaat
    15481 gcgctgttat cgggttagta gctacctttg gtttagcagc ttgtggaaca tctaaggatg
    15541 caagcggtgg aagttcttct ggtaaagaag tattagaatt ttatcatggg tatcatcata
    15601 gtgaagatga atggcctgta gcgaagacta tgcgagattt atatgataaa tttgcagaag
    15661 aacataaaga tagtggtgta gaatttaaac caactcctgt aaatggtgat ttgaaggata
    15721 taatgaataa caaggttgct agtggtgaat ttcctgatgt gattgaccta gcaggtaatg
    15781 cagtatcatt agctgcgatt gaacaaaaac ttgttttaga tttgaaacca tatatcgatt
    15841 caaataagct tgaaaaaaat gttggtttga actataagca aaaccaaaaa gatggaaaaa
    15901 tttatacagt tcacgaacag ttatttacaa tgggtttgtg gtacaacaag gacatatttg
    15961 caaaagcggg tgctaagaca cctgagcagt ggaatacttg ggatgatttc actcaggcaa
    16021 tggcaagcat tagaaaacaa gatggagtgt atgcatttgg tgctggagaa ccatctattc
    16081 gcttgtttaa tacagtatta ggaaccacag aaaatggacg taaattatta gataaaccat
    16141 taacaaaaga aggaattgaa tctaaagaat ttgcagatgc tttgaaaatg gttatgaaag
    16201 aaattcaagc taatggttct aagaatgctg gtggcgatgc caatgcttat tccaaagatt
    16261 tccaagaagg taaatctgca gtattcttta atggtgtgtg ggcttctggt gagatgtcta
    16321 agaacccaag tcttgcacct ggaatctatc ctgcaggtgt agcaattagt tcttctggag
    16381 gtggtatcac tatctcaagt aagatgtctg aagctaaaca aaaactagct cttgagtttt
    16441 tgaaatatat gactagcgat gatgtacaaa aagtaatttt tgaaaaagta ggagcaaatc
    16501 cttctaatga aaatgtaaat gtaaaagaac tttcagaaaa gagttcagaa gctactacta
    16561 aaattttagg acaagcaatc actcaagtta agaatgcaaa agcagttgtt ccaactgtaa
    16621 gtgatgtttg gggtggcgat gtacacacag ctattatcaa tgcattgaca gaaagtgctg
    16681 ctgaaaatgt agatgttgat caaaaagtaa aatctactca agatgtgttg aaatcattga
    16741 ttggttaatt gttttaggga gtgaaaacga agctcagttg gcactgccaa ctgagcttga
    16801 ttttacttat atagttgaaa aaaggagttt gtttatggca caaaaaatta tgagcctaca
    16861 aaataggaag aatcaaaaaa gacgatttat ctttttattt cttttgccaa cgttgatttg
    16921 tttctttcta ttttattttt attctgtagt aacaatcttt ttaacttcat ttgctaaatg
    16981 ggattataca aatttaaaca cccctgagtt tcttggattt gataaattat ttgaaaatta
    17041 taggtatgtt tttaaagaat acccattttt tacagaagct ctaattaatt ctgttcgttg
    17101 ggctgtaatt ggtgttatta ttcaagttcc tttagctgta tctgttgcaa ttacattatc
    17161 taagaaatta aaaggctgga agatatctag gaatctttat attgtaccaa gtatcatttc
    17221 tagtgctgct atgggcttga tttttcttca aatctataat ccaaactatg gtgttgttaa
    17281 ccaaattatt catctattta atccatcgtt taaagattca gtactgttga ctccaggatt
    17341 aaatatagta gctatgactg gcgcttatat cttctttgca ggagcatcaa ccattatgat
    17401 tcttgggcaa atttttgcta ttccagaaga agttcaagaa gctgctattt tagacaatat
    17461 tactggttgg aggaaagagt ggtatattac gattccgatg attaagggga caattaaaac
    17521 tgtttcaatt atggcagcaa cttcagggtt tttgctctat aacgaagtat tctttttgac
    17581 aaatggtgct gcaggaacaa aaagtatcag ttttgttatt cgagaattag cagtggctag
    17641 ctcacgaact cagtatgctc gtgcaaatac aattggagtt atacaaattt taggtggaat
    17701 gttgattatc ttttgtatta atattttatt cagagaaaga aaaagactga aaggtgggaa
    17761 atgattatga atacacatat aaatggtatt agtaaaaaag gcaaagttct tatatatggt
    17821 tatatgctcc ttaccatttt aatttctatt ttccctattg cgtggatttt tttatcatca
    17881 ttaaaagcag atcctatgaa aaatccaggt attagtttac cgactgactt tactcttgaa
    17941 ggctatataa atgtttttac aaaacttcat gttttcactt acttttggaa tagctttaaa
    18001 gtagtgtcta tatcagttat tattagcatt gttatgatct ccatgtcttc atatgttatt
    18061 gctaggatgg aatttagagg gaagaagttg gtgacttcta tgctgtattc tactctattt
    18121 attccagcaa cagctatgac ttttccagtt tatagattag taaatgagtt ggggatttat
    18181 aataccccag ttgctctaat tctggtctac tcttgtagtg gaattgctat gagtttcttt
    18241 attataaaga actattttga aattattcca aaagaattgg aggaggcagc agagattgat
    18301 ggtgcgacat atgctcaaac tttttggaaa gtgatgttac caattgctag accaggaatt
    18361 ttaacagcag cagtacttgc ctttattaat aactggaatg aatattattg ggcatctatg
    18421 ttggtgattg ataaaaatga attaacagta ccagcattac taggtcaatt tactacaagt
    18481 tttaatacta attataatgg tctattttca gctattgttg taatcgtatt accaccaatc
    18541 attctattcg catttacaag taaatacttc attgaagctt taggaggagg agcagtaaaa
    18601 ggatgaaaca tacacttgaa actatcaata gtagaactca gtggtttaga gaagcaagat
    18661 ttgggatgtt cattcattgg gggttatatt ctattccagg aaaaggggaa tggattcgta
    18721 gtcatcagaa attatctatt gaagattatg aaccatattt tcgagctttt gatcctaagg
    18781 aatataaccc tagagaatgg gctaaacaag caaaagctgc agggatgaag tatatggttt
    18841 taacggctaa acatcatgat gggttttgtt tgtttgattc aaaatttaca gattataaag
    18901 caacaaatac acctgcaggt agagatttag ttaaagaatt tgtagatgct gttcgagctg
    18961 aaggtttaaa agtaggctta tattttagtt tgattgactg gcaccatcct gatttcccta
    19021 aatatgctga tctaaatcat ccaatgagag gaaatgaagc ctatcgagat gagaaaatta
    19081 actttgacag ttatttggag tatttacaca atcaagttaa agaaattgta actggttatg
    19141 gtcagattga catattatgg tttgattatt cttatgaaga catggtgggt gaaaaatggg
    19201 gagcttcaaa attaatagac atggttcgtc attatcagcc aaacgttatc gtagataata
    19261 gattagaaac atcaggtgaa ggattcggaa gtatcgttac agatgaaatt acctcttacg
    19321 ctggagattt tgttagtcca gagcaaattg ttcctcacga aggtattcga aactttaaag
    19381 gtgaacctgt tccttgggaa ctttgtctaa ctatgaataa caattgggct tataatccta
    19441 cagattatct atataagtct agtcaaactt tgataagaaa gttagtggaa tgtgttagta
    19501 aaaacggaaa tatgattctt aatgtaggcc cagatgcttt gggaagaatt aatgattcaa
    19561 gtaagaaaat attagataat tttcatcgat ggatgtctcg aaatggtgag gcaatttatg
    19621 gatgtagtgg agatgaaaat ttaccaaaac cagattgggg atactatact cgtaatgaaa
    19681 atacggttta tgctcatgta tttgaacaac ctataggtcc tttagctctt cttggtatta
    19741 gtaaagaaaa cgtaaaaaga atgagctttc ttcatgatgg aagtgaggtg aaaatttcag
    19801 aaagctggac gaccaatgcc tacaaaggaa tttgttttgc acagtttgga gaagttccac
    19861 attttaccta tccattacca gacttgattg atagcgtaat caaaattgag ttgagagagt
    19921 agtttatatg aaaattgaaa ataaaaatgt aagacgtaat ttcttttggg gagatggtcg
    19981 attttatact actgatatcg taaacaaacg ggcaggagta atgataaaaa atgtttcgaa
    20041 agaagaattt accattacat tggagaatgg tataagactt tcttcaaatc atttttcagc
    20101 aatcgttagg gaagagggag atatgcgaat tcaggtttct tttgtttgtc cttccattcg
    20161 tttacgttta atctttgaat cgagggatga tgttctttcg aagcaattag ttttagaatc
    20221 atctactgag gttattaaat ctgtagaggt agagagtttt gagtttgaaa cagaagacaa
    20281 tattttctat ccgaaaagac aagattgtat taaggaaatg gcgaattttt ccggttatta
    20341 tgtagaattg ggacaacctg tttatgcgaa ttctttattc ttaggaatgg aatttccaat
    20401 gtctgaaaac aaggtagatg gtagacacta tgtatcaaga tattacttgg gaactgttgt
    20461 aaatcaagaa aagagtttgt ggtcttgtat tattggggga gcatgttctt ataaaaaaga
    20521 agagattcaa gaggcatttt ttgaatatgt tgaaggaata gctcaaccta gttatttccg
    20581 taaacagtat aattcctggt atgaccatat gaccgatatt acagaggaag gtattttaaa
    20641 aagtttttct gagattcgag atggatttga aaatcatgga gttcatttag atgcttatgt
    20701 tgttgatgat ggttggacaa actatcaatc agtttgggaa ttcaatcata aattcccaaa
    20761 tggtttgaga aatattaaac atcttgtaaa tggatttggt tcaagcctag gattgtggat
    20821 tggtccccga ggtggttata atgggacaga aatcattatg agtgattggt tagaagcaca
    20881 tccagagtta aatattggat ctaaaaattt gatttcaaat gatgtaaacg tggctgattt
    20941 taactatctc aatcaaatga agaaaaagat gttggaatat caaaaagaat tcgatatcag
    21001 ctattggaaa attgatggtt ggttacttca acctgacaaa cctgataaga gtggaccgca
    21061 cggtatgtat accatgacag cggtttatga gttcttaatt caactgttga tagatctaag
    21121 aaaggagaga ggaggaaaag attgttggtt aaacttgact tcttatgtaa atcctagtcc
    21181 atggttttta cagtgggtca atagtttatg gattcaaata tctcaagatg taggctttac
    21241 agagaatgca ggtaatgata tcaatcgtat gattacttac cgagatagtc agtatcaaga
    21301 atttttggaa aaacgtgaga tacagttacc tatgtggtcg ctttataatc atgaaccaat
    21361 ctatgctgtc agtacaaata cctggtacat ggatcatcaa atgtttgcat caataccaga
    21421 ttttgaagct tatctattat ttatttcaac aagagggaat gctttttggg agtttcacta
    21481 ttcttttgat atgtttgatg aagaacgctg gaaagccaat gctcgtgccg tcaaatggat
    21541 agaggagaat tatcaaacac taaaatatag taaaaaaata ggaggaagtc ctgaaaaatt
    21601 tgaaatttat ggttataagt gtcacaatca gaagacttct actgaaattc tctctctgag
    21661 aaatcctgct cagattaaac aaaaaataaa aatagagaat ctttcgatag agaattttac
    21721 cagagtaatt ggagatttta ctattcaaga agatgagata gaattggcac cgtactctat
    21781 cgtgatactg aagaagtaaa gaaaaaattg tgaggtagag atgacgattt atattaataa
    21841 ggacgagacc gtttttcatt tggcaatgaa agatagtagt tatattttta gaattttaga
    21901 aaatggggaa cttcaacatc tacattttgg gaaaaggatt catgtcaagg aaaattataa
    21961 ccaattgatg gcctatgaaa aaagaggatt tgaagtatct ttttctgaag aatttgagga
    22021 tattcaacag tctatgatac aaaatgaata ttcttcatat gggaaaggag attttcggca
    22081 tccagccttt caagttcaag gaatgaatgg tagtaggata acgacactaa aatatcaagg
    22141 ttttgaactt gaaaaaggga aaaatcgtct taactctcta ccttcaacat ttgatgatat
    22201 tggtcagtgt gcggaaacat taacgattat tttaacagat tccatattag atttaactgt
    22261 tagactaaat tacacaattt ttccggaata caatgtctta gttagaaata cggaattttt
    22321 aaataatagc aataataagt tgactctttt gaaagcaatg agcttacagc tagatctacc
    22381 tgatagtcaa tatgacttta ttcaattttc tggagcatgg ctgagggaac gtcagttata
    22441 tagaacttcg cttagaccag gtattcaagc aatagatagc ttgagatact catcaagtcc
    22501 tcagcaaaat cctttcttta tgctatcaag gagggaaact acagagcata gtggtgaggt
    22561 ttatggtttt aactttatct attctggaaa ttttcaaaat atgattgaag ttgaccattt
    22621 tgacaccgct agagtaacgg taggaataaa tccagtagaa tttcgttttt tattaaatcc
    22681 tgccgaaagt tttgtgacac cagaagcaat tgtgatctat tctgatcaag ggatgaatca
    22741 gatgagccaa caactatcag atttttatcg acatcattta gttaatccta atttttctca
    22801 agctagtcgt cctataatac tcaatagttg ggaaacattt tattttgact tgagtacaga
    22861 aaaaatttta gatttagcaa aggctgctaa agatttaggg atagaattat ttgtactgga
    22921 tgatggttgg tttggtcata ggaaagatga caaaagttct ctgggtgatt gggtaacaga
    22981 tagaagtcgc cttcctgaag gtattggatt tcttgcagat gaaattcaca aaataggttt
    23041 acaatttggt ttgtggtttg agcctgaaat gatttctatt gatagtgatt tgtacaagaa
    23101 tcatgccgat tggactatcc atttgttaga cagagagaag tcagtaggaa gaaatcaata
    23161 tgtgttggat ttgacgagac aggaagttgt tgattatctt tttgattcta tttctaaaat
    23221 cataatcaaa acaaatctgg attatatcaa atgggatatg aatcgtcata taacagatat
    23281 ttatagtatt gaacttgatt ctgaacagca gatggaattt ggtcatcgat atatcttagg
    23341 tctttatcag ttattagatc gtttaataac taagttccct tcagttctat ttgaatcttg
    23401 ttcttcaggt ggtggacgtt ttgatttagg acttatgtat tatgcaccgc aagcgtggac
    23461 gagtgatgat acggacccga tagaaagatt gaaaattcag catggaactt cttatggata
    23521 ttctccatca atgatgacag cccatgtttc tatttctcca aatgaacaaa gtggaagaca
    23581 aacgagtttg gacactagga caaatgtagc ttattttagt tctttcggtt atgaattaga
    23641 tgttacgaga ttgtcggtag aagaaaaaga acaagtgaga gaacaaattc agttttataa
    23701 aaaatatcgt tcattgcttc aatatgggga tttctatagg ataaacagtc cttttagttg
    23761 tgattctgct agttggcaag ttgtttcaaa agataaatgc caatcgattt tattgtatgc
    23821 tcaattgaat agtaagttga atccaggtta tacaagagtt tattttagtg gtttagataa
    23881 agataaatgc tattccgtct ctggatttga tgagttcttt tatggagatg aattaatgaa
    23941 tgctggaata aaagtaagtt taagtaattt agcactttgt gttccagaat atcttacaaa
    24001 attatttgtt attgaagaag ttgtatgtaa atattgagga aataaaaatg gaaagtaaaa
    24061 aaatagcaaa acagatttta atagctacgg ctgttttaac aagtttttta ggaagtaatt
    24121 tggtttatgc agatgtagtt caaagtaatt ctaataacag agctagtact gaaactgcta
    24181 gagtaacagg gaataactta gaaaaactta ttattaaaga taaagaaatt gataaagaga
    24241 tgacatatct ttcagatatg gattggtctt ctgcaactca tggtgatata gataaaacaa
    24301 aaacagtaca aaaagatgct ccatttacaa caggaaataa aggagagcat actaagattt
    24361 cattgctcac ttctgatgat aaagttaaat attttgataa aggaatagga acagtcgcag
    24421 attctccatc agtaatcagc tatgatatca gcggtcaagg gtttgaaaaa tttgaaactt
    24481 atataggaat tgatcaaagt gctaatagtt ctagatcaga ccatgcagta gtggatagaa
    24541 tagaaataga aattgatgga aaggttgtct attctagtag tgtaactaat ccagaaggat
    24601 tcagatataa tacccaggca caatttatta gtgtgacaat tccacaaaac gctaaaaaaa
    24661 tatccttaaa atcattcgca ggagaacata catggggtga tgaggttgta tttgctgatg
    24721 ctaaacttat taaaactgtt agtactcaaa ctataactcc agatcttctt aataaaggaa
    24781 ttaatggagg agtatatctt tctgatttag aatgggttga tgctactcat ggtgatgacg
    24841 ataaatcaaa aacagttcag aaagataaac cgtttacacc tggtaataac gggtctaata
    24901 ataaaataaa attactaatt gacggtaagg aagtcgaatt taataaggga ttgggaactg
    24961 tagcaagtaa cccgtctagt ataaaatatg atgtttcggg tgctaatgtt acaagattta
    25021 tttcctatgt cggaattgat aggagtgcaa atcatttaaa ttcagattac gcagatattc
    25081 aaaaatttga agttgttgcg gatggtaaag tcatttactc atcagattca aaatatccaa
    25141 aaggaattaa gtatgataca tcggcatttc tggttgatgt tgaaattccc aaagatacac
    25201 agacaataga acttaaatca tattcaggga aacatacatg ggctgacgaa ttggttttag
    25261 gtggagcctt gtttatggca aatggtaaat ttaagaatcc taatgattgg tcagaagttg
    25321 ataaacgtcg tgaaattaat aatgaacatc cgttacttat gatgccttta tatgctaacg
    25381 gagaagagtt taaccaaggg aaatatactt tttggggagg agatacatta acaggtaagt
    25441 gggagaatat accagatgac ttaaaaccat atactgttat acagttacat ccagatgatc
    25501 ttcctaaaag agatggagct gctagagatt tttatgagca tatgttagaa gaagcagcga
    25561 aatatgtaaa tcctaagact ggaaaaatga acccattcca gttattctaa cggtttacac
    25621 tgctggtaat atgccttatt atacttcggc acattggtta agtaccagct ggattgataa
    25681 aatgtatcaa aaatatccaa atttgcatgg tattttcagt actgagaatt attggatttg
    25741 ggcaaatgat attgaaaata aggcggcaga ttacttaaaa gtatcagcta aaaatggagg
    25801 atattttata tgggctgaac aaaataatgg ttctgcaata gaaaaagcat ttggaaaaaa
    25861 cggtaagata gcatttcaga aatctgttga taagtactgg aagaacctta ttttcatgtt
    25921 caaaaataca cctgctgctg agggaaatga ttcaactaca gaaagttata tgaagggact
    25981 ttggctttca aatcatactt atcaatgggg tggtttgatg gatacttgga agtggtatga
    26041 gacaggtaaa tggaaactgt ttgcaagtgg taatatcgga aaaagtcaag gagatagaca
    26101 atggttgact gaaccagagt ctatgctagg agaagaagct ttaggggttt accttaatgg
    26161 aggtgtagtt tataattttg aacacccagc ttatacctat ggtgtaaata ataaagaaag
    26221 cttactcttt agcgaagtaa taaaagaatt ttttagatat gtaatagcgc atccagcacc
    26281 atccaaagaa aaggtacttg aggatacaaa agtattcata catggagact attcaaataa
    26341 aggaaatggt aagttctttg taaacgtaaa tactgataga gaacaaactc cattatacat
    26401 gactggtcgt tataatgtta ttccagctat tccaggtgtt ttaaaaacag ataaattgaa
    26461 agagtctgtt tctggtagcc gtattcagat taaggaaatc acttctccag aatttagctc
    26521 tactcaggct agaaaagaat acttaaataa gctgtatcct atgaattatg aaggagatat
    26581 ctttgctcag aaattagata atagatggtt tgtctataat tataaggtaa atgagaatgt
    26641 taaacagact gggaaattaa aatttaattc tttagaaatg gatgttgaat ttgaacctca
    26701 tacctatggt atttttgaga gaataagtaa tggattgaaa gtgaatttaa ataattttag
    26761 aacaaataaa gattcactat ggtctaatgc tcaagatgca aatcaggcaa agaaactacc
    26821 acaattgacc aagaaaggtg ccattaagtg gattgaagaa cattatatca aagatactca
    26881 gtttggagag aaaagggtta caaagatagt attaagaggt atagataaac ttcctactat
    26941 tcattcatta tcaggaacaa ataattccta tgatcagcca tctctcaatt ttgatcagaa
    27001 aaatcatatg gttactatta ccattaacag taacggaaat cttgaattcg aacttcattt
    27061 ttagaaagga gtgagtttat gtctcaagat gaaaaattaa ttcgtgaaca gatttgtgat
    27121 gtttgtcata agatgtggca acttggttgg gttgctgcta acgatgggaa tgtatctgtt
    27181 cgattagatg aggataccat tcttgcaaca cctactggta tcagcaaaag ttttattaca
    27241 ccagaaaagc tggtgaagtt aaatcttaaa ggagagattt tagaagcaga aggtgattac
    27301 tgtccttcta gtgaaattaa aatgcacatt cggtgctacg aagaacgtga ggatgttcgt
    27361 tcagttgttc acgcgcatcc accgattgca acaggatttg ctcttgcaca cattccttta
    27421 gatacttatt cactaattga gagcgcgatt gtggtagggg caattcctat aacgccattt
    27481 ggagttccgt ctacaatgga agtgccagaa gcaattacac cttatctgcc cgatcatgat
    27541 gtcatgctat tagaaaatca tggagctctg actgtcggaa gcgatgtaat tacagcatac
    27601 taccgtatgg aaactttaga attagtcgca aagacaacct tccacggaag aatgttactt
    27661 tctacaaagg gcattgagga gcaagaaatt gctcgtccga ctttagaacg tctattctca
    27721 atgcgagaaa attataaggt tacaggtcgt cacccaggct accgtaaata taatggcgat
    27781 ggtagtatga aagaaacaga aaaataagag gaaaatagta tgattcaaca tccacgtatt
    27841 ggtattcgtc cgactattga tggtcgtcgt caaggtgtac gcgaatcact tgaagtacaa
    27901 acaatgaaca tggctaaaag tgtggcagat ttgatttcaa gcacattgaa atatccagat
    27961 ggggaacctg tggaatgtgt gatttctcca tctaccattg gtcgtgttcc agaggctgca
    28021 gcttcccatg agttgtttaa aaaatcaaat gtttgcgcaa caattacagt tacaccatgc
    28081 tggtgttatg gtagtgaaac tatggatatg tctccagata ttcctcatgc tatttgggga
    28141 tttaatggga cagaacgccc aggagctgtc tatcttgcag ctgtactagc ttcacatgct
    28201 caaaaaggga ttccagcctt tgggatttat ggtagagatg ttcaggaagc taatgataca
    28261 gatattccag aagatgtcaa agaaaaactt ttacgttatg cgcgtgcagc tcttgcaact
    28321 ggcttgatga gagacactgc ttacctatca atgggtagtg tttcgatggg gattggtggt
    28381 tctattgtaa atccggattt cttccaagaa tacttaggaa tgcgaaatga atcggtagat
    28441 atgacggagt tcacacgccg tatggaccgt ggtatttacg accctgaaga gtttgaacgt
    28501 gctatggttt gggtaaaaga acatatcaaa gaaggagttg accgaaatcg tgaggatttg
    28561 attctttcta aagaagagaa agaaaaacaa tgggaatttg ttattaagat gttcatgatt
    28621 ggacgtgact taatggttgg taacccaaga cttgctgaac ttggttttga ggaagaagca
    28681 gttggtcacc atgctttagt agctggtttc caaggtcaac gtcagtggac agaccatttt
    28741 ccaaatggag attttatgga aactttcctc aatactcagt ttgactggaa tggtattcga
    28801 aaaccatttg tatttgcgac agagaatgat tcactaaatg gtgtgtctat gctctttaat
    28861 tatctattaa caaatactcc acaaatcttt gctgatgtgc gtacttattg gagtccagag
    28921 gctgttgaac gtgtaacagg acatacttta gagggtcgtg ctgcagctgg cttcttacat
    28981 ctaatcaact ctggatcttg tacattggat ggtacaggtc aagctactcg agatggcaaa
    29041 cctgttatga aaccattctg ggagttggaa gaaagtgaag tgcaggctat gcttgaaaat
    29101 acagacttcc caccagcaaa ccgcgaatac ttccgtggag gaggattctc aactcgtttc
    29161 ttgacgaagg gggatatgcc agtaacaatg gtacgtctca atcttctaaa aggggttggt
    29221 ccagtgctac aaattgcaga aggttacaca cttgaacttc ctgaagatgt tcaccatact
    29281 ttagataatc gtacagatcc aggatggcca actacttggt ttgctccacg tttgacagga
    29341 aaaggtgctt tcaagtctgt ctatgacgtc atgaataatt ggggagctaa tcacggagcc
    29401 ataacatatg gccacattgg agcagacttg attaccttgg cttctatgtt gagaattcct
    29461 gtcaatatgc ataatgtacc tgaggaagat atctttagac ctaaaaattg gtccttattt
    29521 ggaacagaag atctagaatc agcagactat cgtgcatgtc agttgttggg accactacat
    29581 aaataaaact tgtttatata ggaggtgaac ttacgtccct cctatccttt taaaaagatt
    29641 tgttaaacaa ttcacaaata attgaaaacg aatacaaaaa gtaatataat gatgttaaat
    29701 agatagcgcg gaggcgcagg aggaaaatta tatggctata ttttatgttc cggcagtcaa
    29761 ccttattgga aaaggtgttg taaatgaagt gggtccttat atcaaggaac ttggctataa
    29821 aaaggcactt ttggttacag ataagtacat cgaaggcagt gatattttac ctaaggtttt
    29881 aaaaccactg gatacagaag gaatcgaata tgtcatcttt agcgatgtag agccaaaccc
    29941 tacttgtaag aatgtcacag atggggtagc tgctttgcaa gaacatggct gtgactttat
    30001 catcagtctt ggcgggggtt ctccacagga tgcagctagt tgtatttcta tcatggctat
    30061 aaatggtgga aaaccacagg attatgaagg gcttcataag tctgctaaaa aaggcttgcc
    30121 agttgtggct atcaatacaa cggcaggaac ttctgcagaa attaccatta actatgtgat
    30181 tactgatgaa gaacgcaagg ttaagatggt aatggttgac aagaatagcc ttgccttgat
    30241 ttctgttaat gaccctgaat tgatgatttc aaaacctcaa gccttgactg ctgctactgg
    30301 tatggatgct ctgactcacg ctgttgaagc tttggtaaca cctggtgctt atgatgtaac
    30361 caagaaactg tctattggtg ctattgagct tatcaaggaa tatcttcctc gtgctgtagc
    30421 aaacggacat gatattgaag cgcgtgaagg tatggtcaat gccatcttcc ttggtggtat
    30481 gagctttaat aatgctggtc ttggctatgt tcactcaatg gctcaccaac tcggtgcagt
    30541 atataatttg ccacatggtg tttgctgtgc catgttgcta ccagttatag aacgtgaaaa
    30601 tgctaaacgt gtaccagaag ctttccgcaa tgttgccaaa gccttgggac ttcatgtaga
    30661 aggtaaatca gatcaagaat gtgccgatta tgcgattgct gagattgaga agctttctga
    30721 gacagtaggt attcctaaga aactgactga acttggtatt gaagaaaaag atttcgactt
    30781 tgaatacctt tctaagaatg ccttgattga tgcctgcgca ccaggaaatc catttatgcc
    30841 aaccttagaa gaaacgattg ccttttataa agagttattt tagcaagaga ttggacgaca
    30901 ataggacaat tcacctctaa ttattgacat ttcaggaaaa atcgcagtaa aaacggcaca
    30961 gccttcttta aatgtgctat aatactagaa aaatacttgt ggaggttcca ttatggcaat
    31021 atttttcatg atttttctga ttgtttgtgt gctcctattg gtgatagtca cactgagtac
    31081 agtttatgtg gttcgtcagc agtcggtggc gattattgaa cgctttggga aataccaaaa
    31141 ggttgctaat agcggtattc atattcgctt gccttttggg attgactcga ttgcagcacg
    31201 gattcagttg cgcttgttgc aaagtgatat tgtggttgag actaagacca aggacaatgt
    31261 gttcgttatg atgaatgtag cgactcagta ccgtgtcaac gagcagagcg tgacagatgc
    31321 ttactataaa ctcatacgtc cagaatctca gattaaatct tatatcgaag atgctcttcg
    31381 ctcttctgtt ccaaaattaa ccttggatga attgtttgag aaaaaagatg agattgccct
    31441 tgaggttcaa caccaagtag cagaagaaat gaccacttac ggctacatta tcgtgaaaac
    31501 cttgattacc aaggtcgaac cggatgcaga agttaagcaa tccatgaatg aaatcaatgc
    31561 ggcgcaacgt aagcgggtcg cagcacaaga attggcggaa gctgacaaga ttaaaattgt
    31621 cactgcagct gaagccgaag cagaaaaaga ccgccttcat ggtgtgggga ttgcccaaca
    31681 acgtaaggcg attgtggatg gattggcaga gtctatcacc gaactcaagg aagccaatgt
    31741 tggcatgaca gaagaacaaa tcatgtctat cctcttgacc aaccagtatt tggatacctt
    31801 gaataccttt gcctctaaag gaaatcaaac tatcttttta ccaaatacgc caaatggtgt
    31861 ggatgatatc cgtacacaaa tcttgtcagc ccttcgcgct gagaagaaat aatagactaa
    31921 tactcttcga aaatctcttc aaaccacgtc agcgtcgcct tgccgtatag atgtt
//
LOCUS       DAVLZS010000023        31577 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLZS010000023 DAVLZS010000000
VERSION     DAVLZS010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31577
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.023"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            82..675
                     /locus_tag="VYO88_001113"
     CDS             82..675
                     /locus_tag="VYO88_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEV1719223.1"
                     /translation="MLNEKRKNYVEDKRQNFPSLLNWKMDLFSEEEKRNYFQTTCEIS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIMDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVNDIHKLGYKIVDIAPTNFIYTKNVLTPKS"
     gene            complement(685..1956)
                     /locus_tag="VYO88_001114"
                     /pseudo
     CDS             complement(685..1956)
                     /locus_tag="VYO88_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(2331..4301)
                     /gene="tkt"
                     /locus_tag="VYO88_001115"
     CDS             complement(2331..4301)
                     /gene="tkt"
                     /locus_tag="VYO88_001115"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1719224.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYNDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLMSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            complement(4338..5033)
                     /locus_tag="VYO88_001116"
     CDS             complement(4338..5033)
                     /locus_tag="VYO88_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1719225.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            complement(5044..6129)
                     /locus_tag="VYO88_001117"
     CDS             complement(5044..6129)
                     /locus_tag="VYO88_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEV1719226.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            complement(6155..6466)
                     /locus_tag="VYO88_001118"
     CDS             complement(6155..6466)
                     /locus_tag="VYO88_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV1719227.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            complement(6494..6943)
                     /locus_tag="VYO88_001119"
     CDS             complement(6494..6943)
                     /locus_tag="VYO88_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1719228.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            complement(6921..7349)
                     /locus_tag="VYO88_001120"
     CDS             complement(6921..7349)
                     /locus_tag="VYO88_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1719229.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKPPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            complement(7342..8805)
                     /locus_tag="VYO88_001121"
     CDS             complement(7342..8805)
                     /locus_tag="VYO88_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1719230.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKG
                     INKDCPIEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFRMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSAFLTEGDKQRLQAKIQEINYE"
     gene            complement(9334..11670)
                     /locus_tag="VYO88_001122"
     CDS             complement(9334..11670)
                     /locus_tag="VYO88_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1719231.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKMF
                     GASQGWSELEISTLLYYLLGSIGFLSVFRACMPFTFWRVLLIVWSVGGFLATALFLRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            11803..12552
                     /locus_tag="VYO88_001123"
     CDS             11803..12552
                     /locus_tag="VYO88_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1719232.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            complement(12844..13458)
                     /locus_tag="VYO88_001124"
     CDS             complement(12844..13458)
                     /locus_tag="VYO88_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1719233.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(14273..14542)
                     /gene="rpsO"
                     /locus_tag="VYO88_001125"
     CDS             complement(14273..14542)
                     /gene="rpsO"
                     /locus_tag="VYO88_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1719234.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            complement(14683..15312)
                     /locus_tag="VYO88_001126"
     CDS             complement(14683..15312)
                     /locus_tag="VYO88_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1719235.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKLIELFNQLLAGTQTRFLVIGGAGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            16171..16494
                     /locus_tag="VYO88_001127"
     CDS             16171..16494
                     /locus_tag="VYO88_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1719236.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSKNIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            16552..18495
                     /gene="thrS"
                     /locus_tag="VYO88_001128"
     CDS             16552..18495
                     /gene="thrS"
                     /locus_tag="VYO88_001128"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1719237.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVNYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(18544..19518)
                     /locus_tag="VYO88_001129"
     CDS             complement(18544..19518)
                     /locus_tag="VYO88_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1719238.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALVFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(19511..20188)
                     /locus_tag="VYO88_001130"
     CDS             complement(19511..20188)
                     /locus_tag="VYO88_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719239.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGVEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            20344..21417
                     /locus_tag="VYO88_001131"
     CDS             20344..21417
                     /locus_tag="VYO88_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1719240.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            complement(21508..21810)
                     /locus_tag="VYO88_001132"
     CDS             complement(21508..21810)
                     /locus_tag="VYO88_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719241.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(21879..22316)
                     /locus_tag="VYO88_001133"
     CDS             complement(21879..22316)
                     /locus_tag="VYO88_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1719242.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            complement(22392..23234)
                     /locus_tag="VYO88_001134"
     CDS             complement(22392..23234)
                     /locus_tag="VYO88_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1719243.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            23346..23996
                     /locus_tag="VYO88_001135"
     CDS             23346..23996
                     /locus_tag="VYO88_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1719244.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            24173..24819
                     /locus_tag="VYO88_001136"
                     /pseudo
     CDS             24173..24819
                     /locus_tag="VYO88_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            24950..25363
                     /locus_tag="VYO88_001137"
                     /pseudo
     CDS             24950..25363
                     /locus_tag="VYO88_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            25382..25569
                     /locus_tag="VYO88_001138"
                     /pseudo
     CDS             25382..25569
                     /locus_tag="VYO88_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25836..26279)
                     /locus_tag="VYO88_001139"
     CDS             complement(25836..26279)
                     /locus_tag="VYO88_001139"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1719245.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGVAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(26309..28531)
                     /locus_tag="VYO88_001140"
     CDS             complement(26309..28531)
                     /locus_tag="VYO88_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1719246.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            29526..30155
                     /locus_tag="VYO88_001141"
     CDS             29526..30155
                     /locus_tag="VYO88_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1719247.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVCETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFHFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLSNYDVYPGHGPATTIAHEKAFNPFF"
     gene            30341..31577
                     /locus_tag="VYO88_001142"
                     /pseudo
     CDS             30341..31577
                     /locus_tag="VYO88_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         9578 a         7026 c         5670 g         9303 t
ORIGIN      
        1 cattctccag ttcattatag atatagtgct tttttaaaaa aacaggctta tgatgaaaaa
       61 aataaaaagg tcagctattt attgctaaat gaaaaaagga agaactatgt agaagataag
      121 agacaaaatt tccctagtct ccttaactgg aaaatggatt tattttcaga agaagaaaaa
      181 aggaattatt ttcaaaccac atgtgaaatt tcaagtaaag actctgcaat aaataaatac
      241 aaaatggaaa aaattattaa gagatcaaat aaagggaatg tttatcgggc gattagaaaa
      301 tcggatgggc aaaaagtaat catcaagcag tcaagacctt ttgtgaatta tgatgctgaa
      361 ggagaatgga cagctcttga tgatataaaa aatgaagctc acatgctaaa aaaattagcc
      421 gataaaagtt atactactaa tttaactgat gaattttata tcatggatga ttattttctt
      481 gttcaagaac aagttgacgg gttaaacttt gaagaattta ttcgagaaac agaacactcc
      541 ttaaatatta gagaaaaaac actggataac attgtgaata tagtaaatga catccataaa
      601 ctgggatata aaattgtaga tatagctcct acaaatttta tatataccaa aaatgtactg
      661 accccaaaaa gttagacaat taatttatcc gaaggattta gttctgtatt gcacagggct
      721 aagtcctttt agttttacct taattcgttt attgttgtag taatcaatat agtctacaat
      781 ggcttgttcc aattgcttaa gcgactgaaa tgacttctca taaccataaa acatctccga
      841 tttcagaatg ccaaagaagg actccatcat accattgtct gggctattac ccttacgtga
      901 catggatgct tgaattccct taccctcaag aaaccgatga taagaatcgt gttggtattg
      961 ccagccttgg tcactatgga gaatcgtatt ctcgtagtgc ttctctgtga atgcctgttc
     1021 caacattgtt tgtacttgtt ctaaattagg cgaacaagaa agattaaaag caataatttc
     1081 gctgttaaag ccatctaaaa ctggtgataa gtaaagcttt tgagtacttg ctggaatggc
     1141 aaattctgtc acatctgtat agcacttttc cattgtttta gagccttcaa attggccttg
     1201 aatgagattc tctgccttct tgccaacgtc tcctttatga gaagaatatt ttcgtttctg
     1261 tcgcatttta gcttgtaaat tgagtacttt catcaagcct tgaactcttt tatgatttac
     1321 cagataacca cgatttctta gttctaaata aatccgacga taagcataat ttcccttgtg
     1381 ttcgataaaa atggattgaa tttcagcttt aagctcttgg tccttatctg ttttgtctag
     1441 ctgtttcaag tgatagtagt aggtccaacg agctagttta atggatttta gaagaagaac
     1501 taacgaaaac tcagtcatta attcttgaac aatttctgtc tttcttattt ctctttttcc
     1561 ttcttcaatc ggagttctct taactttttt aggatggcat tctccgctct caggtactct
     1621 cccttttgtt ttctcaacaa tagtataccc gtttttcctg tattgtgcta gccagttaag
     1681 aagtatcgta cgacttggga gaccgtattc aagagaaact ctatctttag tccagccttc
     1741 atgtcagact ttattaatca tttcttgttt taaatcagga gaatagtaac gatttttccc
     1801 ttttttgacg aactctattc cgtaacgatc aatcaattta atcatgtacc taagattaga
     1861 attatttatc ccaaatttat ttgaaagctt ctctaagata tatccttgtt ttctaagttc
     1921 atagaactga actttatcat cataagttaa tttcataata aaaacacccc aaaagttaga
     1981 tttttttctg tctaactttt ggggtgcagt tcatcatttc aacatcctat actatgcgtt
     2041 ttttaatttt agagaccttc tctctagctt tcaaaaaact tacaatatcc taagtcaatc
     2101 tgtggatgct gtgtttattg attaaagaaa ctatctagat cagtagcaaa gtgattagcg
     2161 tacttcgcaa ccgtttcagg gtatactcta ttgtgtatac tatctactat aactttcgta
     2221 gataaattat tacattttca ttacagtttt taaataacca atcatctgat tagtgtctat
     2281 cactacatct gctagtctga caacagctgt atcttcattg taattggttt ctatagggac
     2341 ttaacttgag caacgatatt ctctaccgta aatccataat tatcaatcac agtctgagct
     2401 ggggcagacg caccgaagat gtcaataccg atgaccgcgc catccaaacc aacatacttg
     2461 taccaacttt gggtcgctgc catttcaatg gccacacgac gacgagtctt agatggtaaa
     2521 atgtcttcct tgtaggtagc atcttgagca tcaaatagtt cggttgaggg catagatacc
     2581 acacgtactt taccaccttg taaaaccaat tccttagcag ctttgatagc tagattgacc
     2641 tcagatcctg tagcaatgat aatagtatca aatcccgggg tatcatacac gacgtaggct
     2701 cctttagcga ccttaccaaa gtctgtccct tcttcaacta ccaagttttg acgggttaag
     2761 acaatgacag ttggagtggt ggtactggtc aaggcatgat gccaagccgc ttgagtttca
     2821 cgggcatccg ctggacggat aacagtcaag tttggcattg agcgtaaacc tgccaaatgt
     2881 tcaactggtt catgagttgg accatcttca ccaacggcaa ttgaatcatg ggtaaagaca
     2941 taagttacag gcaactcctg aatggctgat agccgaatag cagctttgac gtagtcagag
     3001 aaaacaaaga aggttccgcc ataaactcgt aaaccaccat gaagagccat tccattgagg
     3061 attgttccca tggcaaattc acgtacccca aactgaatat tgcggtttaa tggattatat
     3121 ttatcttgta agccatctgc cttgatgtag gtcatgttgg agtgagctaa gtctgccgat
     3181 ccacctaaga aggttggtaa aactgctgct gctgtattaa tagcatcttg ggacgaatta
     3241 cgagttgctt gagagaagcc attctcatag acagggaagt ctttttcagt aatggttaca
     3301 ggggattttc cagctacaat agcgtcaatc tcactagcaa cttcgggata agcaaccttg
     3361 taatcagaca tcaaactagc ccaagcatcg tatgcctcct gaccacgatc cgctacattt
     3421 gtcttgaaat cagaatatac ttcctctggt acttcaaatg gatcgtaatc ccatcccaaa
     3481 aacttacgag ttgctcctgt ttcttctgct cctagtggtg caccatgaac agcatttgta
     3541 ccacttttat tgggtgagcc gtaaccaatt accgttttca cttcaatcaa actcggctta
     3601 ccagaaaact tggccgtctc aattgctgta gaaattgctg ctaaatctgt tccatcttct
     3661 accagaactg tatgccaacc ataagcatcg taacgggcgc gaacattttc agagaaagta
     3721 tctttggtct caccatccaa gcagatgtcg ttggagtcgt agaggacgat aagcttatct
     3781 aaagcttgat gacctgcata agaagccgcc tccgcagaca ctccttccat gaagtcaccg
     3841 tctccagcga taacataagt ataatggtca aaaataggga aaccatcttt gttgtactta
     3901 gcagctaaaa aacgctctgc ttgggcgaaa ccaacggcag tagaaatccc ctgaccaagc
     3961 ggaccagatg tcgcatccac accagacgta tgcgtcactt caggatgacc aggtgtctta
     4021 gatccccatt gccggaaatt tttaatctca tccatggata catcgttata ccctgttaaa
     4081 tgcaagagag catacagtag cattgatcca tgacccgcag acaagataaa gcgatctcgg
     4141 ttaatccagt ttggctgctc aggtgtaatt ctaaggtgct ttgtaaatag gctataagcc
     4201 attggcgcag cacccatgac gattcccggg tgaccagaat tagatttgtt aatagcatct
     4261 acgccaagaa aacgaatggc gttaactgat tgtagtgaca tatattcctc ctaactaata
     4321 aatttcttct caaaccatta tttgattggc attgtttttc cggtcatttc ttcgtaatct
     4381 ctagaacaga tatcccaggc tttggcaata tcgtcatcca aaccaaataa tccactgcga
     4441 cctataacat aaatatctgg tcctgccaca tcaatttgtt tgaaagtctt acgactcgaa
     4501 gaaccatcca tctcaatgat gtagtgataa ccattctgaa ctctaagctg acggagttct
     4561 tggattttat acaaggtaga ctccaaaaag cgttgtcctg caaaacctgg atctacagtc
     4621 ataatagtta ctttgtcaag taaatcaatg tagggaaaga ttgtagaaac aggtgtttca
     4681 ggattaagga caacaccagc ctttagacct gcatcatgaa ttttatcaat caaacgaaaa
     4741 gcaagaccat tcagaacttc agcatgaata caaatatact cacattgtaa atcgagaact
     4801 tgatctaccc aaaaggttgg gtctgtgacc atcagatgaa ctgataaagg tgtgtcacta
     4861 attttttgaa cttcttgaat gaaccaagga gacaaggtaa tattgggaac aaaatggcca
     4921 tccataatat cgatatgata agatgctact ttatcattca aaaaagtaat ctgctctttg
     4981 aatttgtcca aatccatggt catcaaagat ggtgaaaatt caattcttga catcgttacc
     5041 ctcttacaaa atttcaatat ctgacaaatc aatctcttct tcaacagtca taactggttc
     5101 tgtatgtttt attggttttt tcaaaatcgc gtagacaagt cctgtgacta caatgttggc
     5161 taacaaagca caaataccag ctactggacg agtcatggtt ggtaacataa gcaccccacc
     5221 aaatggcaca gcagaatcag cacccattgt caaagaaaca gcaccaccaa cagcaccacc
     5281 gatacctgtt gcaatgagac ctggaaccaa gttattcata acaatcggaa ttacaccttc
     5341 aacaatattg acaatcccca taggaacagc cgatttcaat gtttcgattt cctcttgagt
     5401 atagatattt tttttgagta atttcgcgat aaaataggcc aatccaaatc caactggtgt
     5461 agcagtattc accaattgca aagcagtcaa tggttctttc acaccttcag cctgtaaagt
     5521 caacacaaac gcatagactg ttttattaag tgggccacca aagtcaacag cactgagaac
     5581 tccaataact gcccccatca aaccatttga agcacttccc aagctttgta ataagctcgt
     5641 caaccagttg gtaaaggctg cgataggcgc tccaataata taaatcataa tcaaactact
     5701 taccaaagag gctacaaaag gaataatcaa ggttggcatt aaacctttaa tccagtttgg
     5761 tactttgacc tttttaataa tcgcttgaac caagaaacca gctatataac ctcccaagat
     5821 accaccgata aaccctgaac caacagaatt ggcaattaga ccaacaacaa aacctggtgc
     5881 aatccctggc ttaccagcaa tcgagtaaga caaacctgta gcaataacaa ctggcaagag
     5941 accaagggct ttaccaccca tagttgctaa agcatcccag atagtgaatt ttcctgctac
     6001 aagagcgtca ggaacaccac cccccattgc taaaccaatg gcaactaaga atcctgcacc
     6061 acaaacaatt ggaatcatat aggaaatggc tgtcaataag tgacctttta agtttaagtg
     6121 tttcaacata tattttctcc ttaaatattt tcagttattt cgtaacaatc tcaacagctt
     6181 tagcaatcag tttattggga gatttgactg ccacttctgt tggaaccttg ataatctttt
     6241 taccctcaaa gcgttccata ccagaaatct taacatcaac tgctaaaata actacatccg
     6301 ctgcatcaat ctgctcttga ctcaattcat tttctacccc tattgtcccc tgagtctcaa
     6361 catgaatcac atgtccagct acctttgcgg cattctctaa tttttcctgt gcaatataag
     6421 tgtgggcaat tcccacagta caagctgcaa caccaacaat tttcatacgg ataccctcca
     6481 aaattttttc ttattaacaa aaagctgcaa tcacatcatc agatgtctga gcccgaacta
     6541 atttggcaac aacttcgtca ttaccaagtt ttcgagcaaa gagtgataag gtcttcaaat
     6601 gctccctagc agcttctgta tcatcaccaa ctgcaaagag tacaattact ttgacccctt
     6661 tcccatcaat ggtctcccaa ggaatctcat tgtgatttat agctatgact acccccgcct
     6721 tctccacagc agaactcttg ctatggggaa tagcaatata attcccaata ccagtctgtc
     6781 cttctgcctc tctctgataa agaccttcga taaattggtc tctatcagac acataacccg
     6841 tctcaaccaa tagttgagct aatgcctcaa aaacctcttc tttgctctgc atctgtaaat
     6901 ccgtctggat cagactcaca ttaagaatat ctttgatttc catatattat ctcccgtaat
     6961 tcttcttttg ttaactgttt taattgattt atgaatgatt catctgctag tcttctcatc
     7021 aatgttttaa tacatgactt gtcctgtgat actgcaatgg ccaaaccgat aataaggtca
     7081 acacactgga tatccttcga ccattctctg ataggtggtt ttaatctagt aatcactaag
     7141 acatgatgtt gaaagtttcc ttcacaatgt ggtagaagaa cacctttagc aacctctata
     7201 cttccctgtc tctcacggta atatagaagc tcttctattt tttctgtatc ttcagaaaca
     7261 agaaggctga tttgatttgc taattctttg taggcttctt gacgattttg aacagatata
     7321 tccataagga caagcgaaag attattcata gtttatctcc tgaatttttg cttgaagacg
     7381 ttgtttatca ccctcggtta gaaaagcact aactaggaca aacgggacac ttgctggttc
     7441 ctgcaaagct accgtcgtca caatgaaatc taaatctgga tatagattta tcagctcatc
     7501 taattgatga taagcaacta catcaataat atccaattca gaaaattgct tttctaatcg
     7561 tgctcgtaaa agctctgaag ttccgacacc tgatgtacac atcactactg tttttagagg
     7621 acgtgctcgc ttttcttgaa accgtgcaaa atataagact agaaaaccaa tctcgtccag
     7681 actcaaggac gcaaaaccaa atactaaact cacttcttta gaaatagttg ttaactcttt
     7741 aaccagatta ggataggtta aaagaatttg tgataaaaga ctattcttaa tctgtactct
     7801 attatctaat ctcctcagta agggactgat atgactcgcc aagtcaacaa agtcaggatc
     7861 tgtcgtttca atctctctat tgtccataca catacggcta aaatagtaat gagtgacatc
     7921 taaaactcgc tgagaaaaag gaagcttccc ggaagaaaat ggtttttgca atctcgaaga
     7981 tacaacgtat tgataaagat agtcaatctc aactgcatca accttcatcc taaaatattg
     8041 ttcaatttct tgaataattt tttgacagac actgtaaatt ttctcatcaa caatagtagg
     8101 ttttgaaggt gctacaacat gaatactagt actacgacga ttcctactga taaaaatata
     8161 caggtgagag aaaatattta tattatatgg atagggaatg tttaccccca attctctctc
     8221 aagtgtaatc agtaatccca aacaaaagtg agcaagttct ccgtcaagag gctgaacctt
     8281 attctgtgta atttgctcta aatccaactg attaaacatt ggcagtagat ttagaatggc
     8341 tgaacgaatt tgagcctcat ccccatcaat aaaaagcttt cgttgtctca tttttaaatc
     8401 taacccataa attgctagac tctcttgtaa tatctgacga tcttttagta ctactgactc
     8461 gcttacgtag aattcctctc ctaaatcata aatagaatgt ggcttaggag cagtcaacaa
     8521 gagacgttct agtaattttt cacgccttac ttcaggatca aaagcctctg taaaattccc
     8581 atcaacgtcc acgagggaac ttcttggatt taatttgaaa cctctgcctt tttcagataa
     8641 aatgaatgct tctatcggac aatctttgtt gattcccttg acaaggcgat aaaccgtttt
     8701 atcagagcaa tttaattttt ctcccaatac tttagcagat atataatcct tactatctcg
     8761 caaaaggagc aacaacgttt ccatttgttc ttgttttcta gacacgatac acctccttta
     8821 tgattccatt atatcgcttt caaaaaataa tatacttcgc attttgtcct ttgcaatgga
     8881 catttttgtt tttatcaaaa atatgatatc aaatagaaca gaacctcact atgccaaaat
     8941 cattttacct tttcttcata acatctattt tagttgaaat atttaagttg cttttcgtat
     9001 ttgataagaa ataaaccaaa cgattttcta ataaataaca ctatgttcca tttaacaata
     9061 gatagcatct tcattttcaa actaccaacc tatccgacca cttgttctag caatagaaga
     9121 gagttaaaat tacttcaatc tgtcgctttc tctttcttac atcaaacttc aaatagtcta
     9181 actacagata tttgaatcta ttacctcaat ccaagcagac ttgagaatca ctcttgggtt
     9241 caccgataga taatagacat gtaggccttg cacatcagat ctacgataga tccatcgtat
     9301 aaaaaactgc aatccacaga ttgcagtctt tctttatttt ttcgcttggt aacgactggt
     9361 caggatgaaa atcacggtaa agaccaacat catgacacca taaacaggta atgtttgtcc
     9421 tgttaaggtt gaaatttcaa gcagtttttg gattcttagg aagagagctg tcgctaggaa
     9481 gcctcctact gaccagacaa tcaagaggac acgccagaat gtgaatggca tgcaggccct
     9541 aaatacggac aagaaaccaa tagaccctag tagataatag agtagagttg agatttctaa
     9601 ctcagaccaa ccttgactcg cgccaaacat tttcacaaag agaacgctga atacgaccat
     9661 aagggcactt ggtagggcac gaagcatgga tcttctgagg aagtttggct cgacaggttt
     9721 gatatttcgc tcaaaagtca aaacgaatgg tgggaaacct tccacaaact ggtcaatcat
     9781 ggtaatctgg atcggaatga aggggaaaat caaaatccac tctgaccgac ctagtaaagc
     9841 actggcaata cagatgactg ctaacaggaa ggaatagatg gtctttatca agaaaatcgg
     9901 ggcgatgtgg gcaatgttat tgaccacgcg acgaccctcg aagagaatct caggaacatc
     9961 attaaagtct gagtttaaga gaaccagatt ggcaatctga cgggttgctg gatccccctc
    10021 cgccatcacg atagaacaat ccgcctcacg aagggccaag atatcattaa ccccgtcccc
    10081 tgtcatagcc gttgtatgac ccgctttttt caacgtttgg atgatgagtt tcttttgatg
    10141 aggggaaaca cgtccgaaaa tagctgtctc ctccgccatg gccatcaatt cctcatcggt
    10201 gatttttgag caatctacat agttgtgata gtccgcaaaa ccagccttct gggcaatgct
    10261 ggacaccgta actggattgt caccagagat aatcttgagt cccacctcct gagaacggag
    10321 atagtccagc gtctctgctg ctccctctcg aatggggtcc aagatttcca gcaaggctag
    10381 agcctgaata tcagatggtt tctgtggttt gtgatggtct aatttctcct gactgagagc
    10441 taagaccaag acacgtgatc ctctctccaa ggcctccctg gcttctggga cttcagaatc
    10501 cagcaacatc tcaggtgccc ctaagaaaac tgtccccaag ccttctaact ccatagcccc
    10561 ccacttgcgg tcgctcgaga agggaagatt ggaaatcata ggataagcaa catctcccac
    10621 aaaacgctgg cgaatggctt gggcagttgg attcttatcc tcactatggg ccatgtagct
    10681 agtcaagatg ctggcaatag cctcttcacc atacgtttcc gtcaacggaa gaacagcctc
    10741 cacctgcatc tttccttggg tgatggtacc cgtcttgtcc agacagagca tatccacgcg
    10801 cgccaaggtc tcaacagagt acatctcctg caccaagacc tttttcaagc caagcttaat
    10861 cactgcagtc aagagcgaag taatggtcaa aagggcaatt cccttaggca acattcccaa
    10921 aagagctgtc gacgagttta caacagatga cttgagaggc aggcctttta aaagcaaggc
    10981 ttccagcaag agagccagac caaagggaat gataatcttc ccagtaaaac cagccaactt
    11041 gtccagcgat ttcatgatac gggagttgat gggtttaacg gtcttagcct caagcatgag
    11101 tttggcagca tagttgtctg caccgacatg gtgaacttga gataaaactg acccactggc
    11161 taggaaactt cctgacaaaa gtaagccgtc aacttccttt tgcaccaaat cactttctcc
    11221 cgttaacatg gcttcattga cttccgcaaa gccttccaaa accaaggcat cactaggaat
    11281 ctgctctcct gcagacaaac gaatgacatc tcctagcact aattcttcag gattaagagc
    11341 aacttcctga ccatcacgga tggttttgac cttttccttg gtcatgagat tgagcttgtc
    11401 caccatgtgt ttggctcgta gctcggtcac aatcccagaa aaagcgttaa agcagataac
    11461 agcaaagaag accagattgc tccaagcctg cacaaaggca agggccaaag caatggcaaa
    11521 gttcaaagcg ttaaaaagag taaagacatt tcgtttaacg atttgccaag tgctggtact
    11581 ggctgatgcg gtaaagtcat tgaccaaacc ctcagcctgt ctttccttga cttctctttg
    11641 ggttaatccc ataatcttat ttttatccat aaattctatt atatcatttt ttttaacaga
    11701 attctaattt catcccaaat atgcatctag tcaagggaaa agtttgccag ccctcctttg
    11761 ataaggtata ataataacaa gaaaacaatc gaaggagatc gcatgtttta tacttatttg
    11821 cgtggattag ttgtattgct cttatggtcc atcaatggca atgctcacta tcataatact
    11881 gataaaattc ctaatcaaga tgaaaattat attttagttg cgcctcaccg tacctggtgg
    11941 gatcctgttt atatggcctt tgcgaccaag ccaaaacagt tcatctttat ggcaaaaaaa
    12001 gaactcttta ccaaccgtat ctttggttgg tggattcgta tgtgtggcgc ctttcccatc
    12061 gaccgtgaaa atcccagcgc ctcagccatc aaatatccta tcaacgttct caaaaaaagt
    12121 gaccgctctc tcatcatgtt tccaagtggt agccgccact caaacgatgt caaggggggc
    12181 gcagcactga ttgccaaaat ggccaaggtc cgtatcatgc cggttaccta caccggtccc
    12241 atgactttga agggcttgat tagccgtgaa cgtgtcgata tgaactttgg aaatccaatc
    12301 gatatctcag atatcaagaa aatgaatgat gaaggcattg aaacagtcgc caatcgtatt
    12361 caaacagaat tccaacgtct ggacgaagaa acgaaacaat ggcacaatga taaaaaacca
    12421 aatccactct ggtggtttat ccgcatccct gccctcatcc ttgctattat cctcgctatc
    12481 ctaaccatca tctttagctt tatcgcaagc ttcatctgga acccagataa gaaaagagaa
    12541 gaacttgcat agaagaaatg aaccttggcc aaacagctaa ggttttcatt tatatagtag
    12601 attggaacta gaatagtaca cctctacttc taaaacattt ttagaaatcg atttgactgt
    12661 cctgatcgat ttgtcctatt cttatttcat tttactatat ttataagaat ctcctaatca
    12721 aatcaaaagc cactctacaa tagagtaact ttaagattgt ccatttatgc tcaatgaaaa
    12781 agccctctga aaatcagaga gctgatttga gctcgggcta aaatcctaat gaaacaaaaa
    12841 aatctacacg atcagaaaag tctctatcgt gccattttca tacatgatgt atagtccaag
    12901 tagaatgaat actaagggca caatgattcg ctcgtatttt tcaattgtct cgaatattaa
    12961 cggaatagag gataacaccc gactaatctc gcaaaagata attatgccga ttacaaacac
    13021 aagcaaggcc acgagggtct gtgaccaatc taacgaagca aaataaggta tatagatacc
    13081 taaattatct ccgccagacg caattgtcag caatgtaact gtccaaaaca gttgatttgc
    13141 cttgctttgt tctaatcttt caataatttc ttcctcttct tcttccgcat cttctccaac
    13201 aattgcaaag cgaatcccta aatagatagg gattaaacca agcaatccaa ccatccattc
    13261 ttcaggcacg aaattaacga cataagcagc aactaaactc gcccctacaa gtaagcctgt
    13321 gcctagatat tgccccgcat aaatatgcca tttctgttta ttctgtgata gctgtgcaaa
    13381 taaaataatt aaaataatta aataatcgat actggtggaa atataaacac caatagcaga
    13441 tatgattgtc tgtcccataa aaaaaacctc ctgtattagt cagtaataaa tcagcagatt
    13501 tcaggagagc acagacacat taatttagct atcgctagtg ggtaatgtcg aacgtaggaa
    13561 agcattttac tcctcctcaa aacgtagtta caaagtaatt tctaactgga attcagtgac
    13621 tacttccatg taaagtataa catactatac tttactttgt aaagagtggg ctcttctagg
    13681 gggcttgcat acagctactc ggcttgaaaa gccgagtaac tgcgcacctt tatggtgtaa
    13741 ttagctgata ccatttgagg tttttgtagt ctccaaaatt gttaccgata aaacctcaat
    13801 aaaaaagccc tctgaagtca gagagctgat tttagcccgg gctaaaatcc tagtgaaaaa
    13861 gatgaaactc cttgtgctca tcgaacactg tgtcatttcc ctattttcat acggattttt
    13921 gacgccctta gcatcatgat tcttgctaga taaatcgttt atagactagg cgacgaggcg
    13981 aagatcgtac gaaactttca gtgaaacaaa aaaatctccc cgaagggaga aaagctggtt
    14041 tattttacct tacagtgcta ggaaccgtaa ccgaagatta tacttgagta tagcgaggta
    14101 aggtgacaac gcaaaaaagc tacccaattt agagtagctt tattatcaag atatgctcaa
    14161 ttgaacacgg cctaagcact tggcaaaaaa gataaaatct cctagaaact gaagtttctt
    14221 cgtcaatttt cctatttttg ctttgtgctt ttgacggcct ttgtatcttg aattagcgac
    14281 gaagtcctag agagttgatc aactcacggt aacggttaac gtcgttttta cgcaagtatg
    14341 caagcaagtt acgacggcga ccgatttttt tcatcaatcc acggtaagta gcgtggtctt
    14401 ttttgtgttg tttgatgtgt tcgttaaggt ggttgatttc ccaagtaagg acagcaactt
    14461 gaacctctac tgaacctgta tcaccttcgt gacgtgcata ttgtgcaatg atttcatttt
    14521 ttttctcttt tgagattgcc atgatgtttc tcctttttat ttggcttcat ccgagtgaca
    14581 ggttggcatg cctgtaacca agaagaagtt atttgtcttt acgacaatcc ctattttacc
    14641 aagatttaaa ttttctgtca aacattaata ctctcatagt tattattttt caagtaaaga
    14701 gatacgttct tttatatgat gacctttttc aagttcatct accaatccaa tagcataatc
    14761 tgcataacta atctggctta ttccttttcc attagtagta aaaatttctc ctgctagaat
    14821 gtagtttcct gttttttcac catcgggaat aaaatctaca gcaggactga caaaagtcca
    14881 gttgagatta ttttttgtac gaagaagatc caattcatcc gcttgagctt ttgctagtga
    14941 cttaaattct tcaggaaaat caggcgtatc taaaagtcgt gtcgtttttg tttcatctat
    15001 ataaaggctt cctgctcccc ctataactag aaaacgtgtc tgtgttccag caagaagctg
    15061 attaaatagt tcgattagtt tgctgtggag cggtagcgta tctggtgtat aagcaccaaa
    15121 cgctgaaata acagcatcaa atccagtaag atcatctttt gtcaactcaa ataaatcttt
    15181 tttaataata gactcagctt gacttttgtt ttcagaacga acaatagccg ttacttcatg
    15241 tcctcgtttg actgcttctt caacaattgc cttccccgct tgtccatttg ctgcaataac
    15301 tgctagtttc attttttata cctctcttgt tgtaattatt ttagttacag caattgtgac
    15361 actcttaata atcaatgtca atagtcttgc ttaattatta tcaaaatatt tctaccaaga
    15421 aaactaacca tgattctagt gaaaagaaaa atcttctttg tcaacaaatt tactttcttg
    15481 ttttaaacat gctataataa tcatagcaag agatctaagt tgtctgtttt tttaaaacga
    15541 ggtgattatc atgcgtagat tctattccca tctcccctac tatctggtca tattattctt
    15601 ttattggcca ctttatgagt tgttcttgct agttgtttct gaccccctta cactatataa
    15661 acaatcttct cttctttaca cctctggtaa tcttgattgt atcgttactc tatagctacc
    15721 gtttccgttt ctcactttga tggttagttg gtaacggact gctcttttac tttactatca
    15781 taacctttgg tgagtttata ctaatttact tgctaatcta tgaaacagtt gctctggtgg
    15841 gcatggattc tggtattagc atcaagcata ttctacaaaa tatgaaaaac aaaaaacttt
    15901 cacaaaatcc ttgaaaaatc tcacaatcat gctataataa tccatagaga caagtcactt
    15961 agtccctttc tactagagag tgcgtggttg ctggaaacgc ataggaagtc taaactgata
    16021 ctactcttga gttttttatg aaaacataaa acggtggcca cgttagagcc aatcagaggt
    16081 gtccctctct tttgaggtac ataaatgaag gtggaaccac gttgcgacgt cctttcgagg
    16141 atgtcgcatt tttttattag gatactaatt atggagttgc aagaattagt ggagcgcagt
    16201 tgggcaatcc gacaagctta tcacgaactg gaagttaagc atcatgattc caagtggacg
    16261 gtagaagaag acctcttggc tttatctaat gatattggaa atttccaacg actggtgatg
    16321 acaaagcaag gacgctacta tgatgaaaca ccctacacac tggaacaaaa actttcaaaa
    16381 aatatctggt ggctattaga actttctcaa cgtttggata tagacattct gacggaaatg
    16441 gaaaacttcc tctctgataa agaaaagcaa ttgaacgtta ggacttggaa gtagtctgct
    16501 gataaaaaat caatgcttag aaactatgaa ataataaaaa aggagaacat catgattaac
    16561 attactttcc cagatggcgc tgttcgtgaa ttcgaatctg gcgtaacaac ttttgaaatt
    16621 gcccaatcta tcagcaattc cctagctaaa aaagccttgg ctggtaaatt caacggcaaa
    16681 ctcatcgaca ctactcgcgc tatcactgaa gatggaagca tcgaaattgt gacacctgat
    16741 cacgaagatg cccttccaat cttgcgtcac tcagcagctc acttgttcgc ccaagcagct
    16801 cgtcgtcttt tcccagacat tcacttggga gttggtccag ccatcgaaga tggtttctac
    16861 tacgatactg acaacacagc tggtcaaatc tctaacgaag accttcctcg tatcgaagaa
    16921 gaaatgcaaa aaatcgtcaa agaaaacttc ccatctattc gtgaagaagt gactaaagac
    16981 gaggcacgtg aaatcttcaa aaatgaccct tacaagttgg aattgattga agaacactca
    17041 gaagacgaag gcggtttgac tatctatcgt cagggtgaat atgtagacct ctgccgtgga
    17101 cctcacgttc catcaacagg tcgtatccaa atcttccacc ttctccatgt agctggtgcg
    17161 tactggcgtg gaaacagcga caacgctatg atgcaacgta tctacggtac agcttggttt
    17221 gacaagaaag acttgaaaaa ctaccttcaa atgcgtgaag aagctaagga acgtgaccac
    17281 cgtaaacttg gtaaagagct tgacctcttt atgatttcac aagaagtggg acaaggtttg
    17341 ccattctggt tgccaaatgg tgcgactatc cgtcgtgaat tggaacgcta catcgtaaac
    17401 aaagagttgg cttctggcta ccaacacgtc tacactccac cacttgcttc tgttgagctt
    17461 tacaagactt ctggtcactg ggatcattac caagaagaca tgttcccaac catggacatg
    17521 ggtgacgggg aagaatttgt ccttcgtcca atgaactgtc cgcaccacat ccaagttttc
    17581 aaacaccatg ttcactctta ccgtgaattg ccaatccgta tcgctgaaat cggtatgatg
    17641 caccgttacg aaaaatctgg tgccctcact ggccttcaac gtgtacgtga aatgtcactc
    17701 aacgacggtc acctattcgt tactccagaa caaatccaag aagaattcca acgtgccctt
    17761 cagttgatta tcgatgttta tgaagacttc aacttgactg actaccgctt ccgcctctct
    17821 cttcgtgacc ctcaagatac tcataagtac tttgataacg atgagatgtg ggaaaatgcc
    17881 caaaccatgc ttcgtgcagc tcttgatgaa atgggcgtga actactttga agccgaaggt
    17941 gaagcagcct tctacggacc aaaattggat atccagatta aaactgccct tggaaaagaa
    18001 gaaacccttt ctactatcca acttgatttc ttgttgccag aacgcttcga cctcaaatac
    18061 atcggagctg atggcgaaga tcaccgtcca gtcatgatcc accgtggggt tatctcaact
    18121 atggaacgct tcacagctat cttgattgag aactacaagg gggccttccc aacatggctg
    18181 gcaccacacc aagtaaccct catcccagta tctaacgaaa aacacgtgga ctacgcttgg
    18241 gaagtggcca agaaactccg tgaccgcggt gtccgtgcag acgtagatga gcgcaatgaa
    18301 aaaatgcagt tcaagattcg tgcttcacaa accagcaaga ttccttacca attaattgtt
    18361 ggagacaaag aaatggaaga cgaaacagtc aacgttcgtc gctacggcca aaaagaaaca
    18421 caaactgtct cagttgataa ttttgttcaa gctatcctag ctgatatcgc caacaaatca
    18481 cgcgttgaga aataagagtc tagcataaaa gcctccaatc tggaggcttt ttctcatcta
    18541 tttttactca aggactaagt tcacttgagc aaactgaatc cgcactgtcg ttccttttcc
    18601 gacctcagac tcgatacgaa tctggtgccc cagttcttca gaaattttct tagatagata
    18661 aaggccaagt ccagaggact gctgggtcaa acggccattg tatcctgaaa agccacgttc
    18721 aaatactcgg aggacatcac tgttttttat cccgattccc gtatctttga tacaaagctc
    18781 ttggtcatcc atataaatct ccagaccacc ttccttggtg tacttgagac tgtttgagat
    18841 gatttgctca ataaccacta gcagccactt tttatccgtc acgatttctt tatcaaggtc
    18901 atgtagattg acatttaagc ctttttgaat aaagacaaga gcatatttac gaattatttc
    18961 cttgaccaag tcctcaattt gaacctgctt taagaccaaa tcatcatgga aactttctaa
    19021 acgcaggtac tgtaaaacta ggttggtata ggagtcgatt ttgaaaattt cctgttctag
    19081 ttgctgcttc agttggcggt cgaccacttc tgcaactaag agttgactgg ctgcaatggg
    19141 ggtctttatc tgatggaccc acaaggtata gtaatccagc aaatccgtca gttttctttc
    19201 tgcttttgac ctctgctgat agagttccat ctcacgcgct tctaattttt ctgctaaagc
    19261 tatttccaaa ggagacttgg cttccctctc tccataaaga agttcctggc gatagacctg
    19321 cgtttccacc aatatatccc aagtgaaaaa taagatggtt acaaagcaac acaagaagaa
    19381 aaagtagagg aagtaaattc ctagactggc aaataaaaac tgaaagagta agaccagaaa
    19441 tgccaaagaa agcagataga taaaaagacg actacgggag cgcagatagg ctagaaaaaa
    19501 ttgtttccaa tcaagcatgc ttcaatccgt accctattcc tttcttggtc tcgataaatc
    19561 ctaccaatcc ctgctcctcc aactttttac gcaaacgagc cacattgaca gagagggtat
    19621 tatcatcaat gaaaaagtca ctgttccaaa gttcccgcat caggtcgtca cgtgctacga
    19681 tgttgcctgc atgctcaaat aacacgcgta aaatctggaa ttcattcttg gtcaaattca
    19741 agacttgccc ttgataatgt aaatccatgg atttggtatt gaggataaca ccagcatatt
    19801 ccagcaaact ctcatcacgc ccaaactcat aggaacgacg caacaagccc tgaaccttag
    19861 ctaaaagaac ctgctggtca aaaggcttgg tcacaaagtc atccgccccc atattgattg
    19921 ccatgacaat atccatagcc tggtctctcg aagaaagaaa catgataggt accttggaaa
    19981 tcttgcggat ttcctgacac cagtgataac cattaaacaa gggcaaacca atatccatga
    20041 ggaccagatg aggttccgac tgaacaaata gactcaaaac ttccataaag tcttctacca
    20101 ggaccacttc aactccccat tcagagagca ttttcccgac ctgttgacga atgacctgat
    20161 catcttccac taataaaatc ttgtgcatgc gcttctcctt ttccattatt ataacagatt
    20221 tttccatgcc agatggtctg aaactgaatt tgaaatagcc tgtttttagc cagtacaaac
    20281 aggcaatgct actagctaat ttgagggaaa tttgctaaga taaataaaaa gaaaggagct
    20341 cttatggcca atatttttga ctatctgaaa gatgtcgcat atgattctta ttacgacctt
    20401 cccttgaatg agttagacat tctaacctta atagaaatca cctacctctc ctttgataat
    20461 ctggtctcca cacttcctca acgtctttta gatctagcac ctcaggttcc aagagatccc
    20521 accatgctta ctagcaaaaa tcgccttcaa ttattagatg aattggctca acacaagcgc
    20581 ttcaaaaatt gcaaactctc ccattttatc aacgacatcg accctgaact gcaaaagcaa
    20641 tttgcggcta tgacttatcg tgtcagcctc gatacctatc tgattgtctt tcgtgggaca
    20701 gatgacagta tcattggctg gaaggaagat ttccacctga cctatatgaa ggaaattcct
    20761 gctcaaaagc acgcccttcg ctatttaaag aacttttttg cccatcatcc taagcaaaag
    20821 gttattctgg ctgggcattc caagggagga aatctcgcta tctatgctgc tagccaaatt
    20881 gagcaaagtt tgcaaaatca gatcacagca gtttatacat ttgatgcacc tggtctccat
    20941 caagaattga cacagactgc gggttatcaa aggataatgg atagaagcaa gatattcatt
    21001 ccacaaggtt ccattatcgg tatgatgctg gaaattcctg ctcaccaaat catcgttcag
    21061 agtactgccc tgggtggcat cgcccagcac gataccttta gttggcagat tgaggacaag
    21121 cacttcgttc aactggataa gaccaacagt gatagccggc aagtagacac aacctttaaa
    21181 gaatgggtgg ccacagtccc tgacgaagaa cttcagctct acttcgacct cttctttggc
    21241 actattcttg atgctggtat tagctctatc aatgacttgg cttccttaaa ggcgcttgaa
    21301 tacattcatc atctctttgt ccaagctcaa tccctcactc cagaagaaag agaaaccttg
    21361 ggtcgcctta cccagttatt gattgatact cgttaccagg catggaaaaa tagataatac
    21421 tcttgaaaat taaatgtata caaaacaaaa gacctagaat acatactttc atgtgcattc
    21481 taagtctttt taaatagaat ctaatagtca ataaaaatca aagagcattg agagataatg
    21541 gggcttggaa cgtccctctc gtttcaacaa aatgacccca ttatagatta aaaagatgcc
    21601 acttagaaaa agcaaaaaag gaagtaagac aaaggcaaat acataaaaag ctaactgaac
    21661 attctcgtat ccatttttat aaaaaaggta ggatagataa aaataacttg aaatgaggga
    21721 taataaaaat aatactggat tccacaaact tctattatcc ttccaaaatg acactataaa
    21781 ggctaataca atttctataa cgagatacat ttcttactcc tttaatagct acattttatc
    21841 ataattatcc aaagaaaaaa agagggcatt tatccctctt aatccttcat ctgactctct
    21901 gcatcggcca cgactttttc tagactggtc tgaccaagtt ctgcctccat agtcaactga
    21961 attctctcca atttttgatc caaaacatca tgaatatgag ctcctacagg gcaatttgga
    22021 ttcggattgt catggaaact gaagagttga cctgtcttac caagacattc gaccgcctga
    22081 taaacatcta aaagactaat atccttaagg tccttgacaa tctctgttcc gcccgttcca
    22141 cgcgctactg aaatcagctc tgccttcttc aactgggaca agatctttct gataatgaca
    22201 ggattgaccc caacactagc agccagaaaa tcactggtca ccttgctttc cttcccctcg
    22261 agggcaatga ttatcagcat atgagttgca atggtaaatc tacttggaat ttgcatcctc
    22321 ttctcctttt tacgaggcta ccctgcctct actcttcttt ttctattatt ataccctttt
    22381 tagttgtaat gtcaatcgtt accacttttc aaccagtcgt ctaactcccg atcgcaaccc
    22441 tctttctgag ccaattctct caaaaattcc tgatgatgag tatggtggat cccattgacc
    22501 agactttcat agtaaacctc aaaataggga agtctcaggt ctttagccag ctgcaattca
    22561 gctgccacat cgtaatctac ccgtcggaag tccatatcta ccaggccctt gtcatcaaac
    22621 tccaaaatca tatactgggc ccgcaagtcc ttccgtagct gagcgtccaa aaagaaaggt
    22681 tggccaatcg aacccggatt gacaattaat tgcccaccag tcccgtaacg aagcaactgc
    22741 tggtgaatat gtccataaac agcaatatca cagggaggat gagtcaccaa gcggtcaaac
    22801 tcctcttgtt tgccagtatg aatcaactct cgcccccagt tcttatcagg cagatgatgg
    22861 ctaattccca ccgtcaaatc cccaaactga cgatgaattt gaagaggttg attgtggagc
    22921 acttcaattt cttctaggga aatttcctct aaaacatact ggcactggcg caagagatag
    22981 cgttgactgg ggcgagtact gtccaattcc ttacggacac catgccaaag actgtcttcc
    23041 cagtttccca aaactctagc cgtaatcggt agttgatcca acaagtccaa aatccttcta
    23101 cgccctgtcc ctggcatgag aatatctccc aaaagccagt attcatccac tcctagctgc
    23161 cgagcatctg ccaaaacagc ctccaaggcg gtggtatttc catgaatatc tgaaagaaga
    23221 gctattttcg tcatatccat ctcctcgttt tttctcttgc aataagtata acataaaaag
    23281 tcacagctag agaaatctag ctttttttga tatactagat aaagatatta gacaagagga
    23341 aacgaatgac cccaaacaaa gaagactatc taaaatgtat ttatgaaatt ggcatagacc
    23401 tgcataagat taccaacaag gaaattgcgg ctcgcatgca agtctctccc cctgccgtaa
    23461 ctgaaatgat caaacgaatg aaaagtgaaa atctcatcct aaaggacaag gaatgtggct
    23521 atctactgac tgacctcggt ctcaaactgg tctctgagct ctatcgtaag caccgcttga
    23581 ttgaagtttt tctagttcat catttagact atacaagtga ccagattcac gaggaagctg
    23641 aggtcttgga acacactgtc tctgacctgt tcgtggaaag actagataaa ctgctaggtt
    23701 tccctaaaac ctgcccccac ggaggaacta ttcctgccaa gggagaactc ctcgttgaaa
    23761 tcaataacct cccactagct gatatcaagg aagctggcgc ctaccgcctg actcgggtgc
    23821 acgatagttt tgacattctc cattatctgg acaagcactc acttcacatc ggtgaccagc
    23881 tccaagtcaa gcagtttgat ggcttcagca ataccttcac tatcctcagt aacgacgagg
    23941 atttacaagt gaatatggac attgcaaaac aactctatgt cgagaaaatc aactaatttc
    24001 tcaagtcccc taccaaccct gaaagtttta ttttcagggt tttatttcta tcattttatt
    24061 ttactttcat ttggtggtag aatatttgaa aaaaagaaag gtagtttaac ctatgaaaaa
    24121 atcactaaaa atttttgcta catctaaatg atttgacctc ttcggggttg ctttggtcgt
    24181 tgggattgcg attgcatctg gttatctcaa ctcacgcctc gataaatttg tagactgggg
    24241 actatggaca gctcttgtac cctttggatt gatttccgta accaacgttg ggatttccat
    24301 gttgtccact cgtttcacgg ggaaattaag caaatgggga aattactttg gtattgttaa
    24361 taccattttg tccggtgcta ttgattatat ccttggaaat aaggcggcca tcattaccta
    24421 tcccgtcacc ttcctcattt atacctttgc tataaagaaa tggaaagctt cgcaagaagg
    24481 cagacccaac caaatgagcc aaaaacaggt aaaattggcg gccatcatca tttccatcat
    24541 cgccttcctc tttgcctttg tgaccaacta tatcggatat gggggcaaga tgaatctcct
    24601 tgcctacgta acaactattg cctttgcact gtccctcatt gccaatgctt tgaatgcatt
    24661 ggcaatgagg gacagtgggg cttttggttg atttacaatt tcgttcagct gacaaaagct
    24721 ggtattcaag gaaacttcgc caatatcggt aaatacatct tttatatcct caatgcaatc
    24781 ggagctttat ttgtctggaa tgatgaagaa gttagataat agaaggaaac tcaaataaag
    24841 aatactagcc aacttaagag aatctcccct ctgctatttt tatcatttta gttgtaactc
    24901 ccattctttt agagtagaat gaagttagat aaaagaggga ggtcttgtca tgaaaaaact
    24961 ctatagaatc cattttatag caattgcagt tattgatttg ctactatttg cattttttat
    25021 cattagactc gagacatctt ttgagtggct cttgctctct ggtttaattt tcttccttgc
    25081 tcaaggactc ctgctatttc tcttgatcgt ccgactcaaa cattaattcg ctgagattta
    25141 tcctcaaatc aataaaaaga ttcgcttcta ctatttaggg gttctcacca ttgattttct
    25201 attttttgtt ctcttagcct tcattagttc tcagcgtttt tcatctctta tgtcaattat
    25261 cactgcttgc cattctactt tttattatat gacagctgac tacctaagag aaaactatcc
    25321 agacttttac gacaaacaca tctctttatg ggagtgtctc taaggaaaag gaggttttag
    25381 catgaaaaaa atcatcttca tcaaaaccat tcaactcctt gtcattgatg gaatcatgct
    25441 ggcatttttg acatttaaaa aggggggctt acttgggact ggattttgat ttatagcggt
    25501 tggctcattt tctttcatcc tgtgctattg acctatcttt caaaccaact ttgtgaccac
    25561 tttagttaac tctattccca gattagaccg agattctggc gttttgcttt acaaattctc
    25621 ctatgggata gcctgatgat tctctccttg gtgtctttaa gtgatattcc acttttcctt
    25681 cagggaactc tcctcatcct aggacatctc atcccttcct atcgcatctg ccaaagcctg
    25741 aaaagagact tcccccaagc atatcaagaa ccgatttctt tttggagtat tttatgatcg
    25801 atgagaaaga ccaagccgac tgggcttggt ctttcttatc tctttttagt atctagaata
    25861 atggtaacag gtccgttatt aaccagctca acctgcatat ctgctccaaa gatacctgtc
    25921 tgaacgggca cttcttgcgc taatttttga ttgaaagcat catagaagtc tgatgccata
    25981 tcaggtttag ctacccctgt aaaggctgga cgattgcctt tcttagtatc cgcaaagagg
    26041 gtaaactgag aaatagagag gatttctcct tcaatatctt tgacagatag gttcatcttg
    26101 ccttctgcgt ctgaaaaaat ccgcatattg accagttttc tcacagcata gtccaaatct
    26161 tcctcttggt cctctggtcc aacaccaacc agcaataaaa gtccctgatt gatttttccc
    26221 tgaatctggc cttctatact cacttgggct tttttaaccc gttggataat gattttcata
    26281 atagcctttc tagtaagagc taggacaact agccgttggt ccgtttgaca gagtaaactt
    26341 ctggcacact cttaatttta tcgacaaccg tagtcagtgt agagaggttg gcaataccga
    26401 aggacacatg gatattagca aacttcatat ccttggttgg ttgggcattg accgttgaaa
    26461 tattcttggt tgtatttgaa agaacttgca gtacatcgtt caacagtcct gtacggttga
    26521 gaccgtagat atcgatatgg gccatatact ccttatttga gctagagtac tggtcttccc
    26581 attccacatc aaggagacgt tgctcgtagt tttcttgggc acgcaggttc atacagtcca
    26641 cacggtgaat agccacacca cgacccttgg taatgtagcc aacaatatcg tcaccaggca
    26701 cggggttaca acacttagca atccgcacta ggagaccaga agcaccttca ataaccactc
    26761 ccccctcatg cttgaccttg agggtttctt tattttcaac cttgacctcg ccacctttga
    26821 caagctcctc tgcctcagcc ttggccttgg cacgctcttc ctcacggcgt tccttttcag
    26881 tcagacggtt aaagacggta atcgcaccga tttccccaaa accaatggcc gcaaagaggg
    26941 agtcttctgt cttgtaactg gtcttttgca gaacttgatc catgtggcgc ttgtccataa
    27001 atttatttgc cacatagcca ttttcttgga actgagccat cagcatctca cgacccttgt
    27061 tgacagacaa ttccttatct tggtttttaa agaactggcg aatcttattg cgcgccttgc
    27121 tagtcttgac catattgagc cagtcacggc taggtccaaa ggagttcggg ttggcgataa
    27181 tttcaacctg atcccctgtc tttaacttgg ttgtcagtgg aaccatgcgg ccattgacct
    27241 tggcaccagt tgctttttca ccgaccttgg tatggatttc gtaggcaaaa tcaatcggtc
    27301 ctgaatcttt gggaagggaa cggacagctc catctggggt aaaaacgtaa atctcctcag
    27361 ccaaatagtt ttccttaaca gagtccacaa attccttagc atcatcagcc tggtcttgga
    27421 gctccatcat ctccttgatc cagttcattc caatagctga ttccttgctg ttaacttgcc
    27481 cctttatacc tttcttataa gcccagtgag ccgcaacccc gtactcagcc acctcgtgca
    27541 tttccttggt tcgaatctgg aattcaatcg gcccttttgg tccataaaca gtcgtatgga
    27601 tagactgata accattggcc ttgcggttgg cgatatagtc tttgaagcga cctggcatcg
    27661 gtttccaaaa ttcatgcacg taaccaagca tggcataaac atcactttgg gtatctaaaa
    27721 tacaacgaat agcaatcaga tcatagattt cctcaaaccg ttttctcttg tcctgcattt
    27781 tgcggaaaat tgagtaaata tgcttgggac gaccataaat cttccctttc aagtgacgtt
    27841 ctgtcgtata ctcctctaat tttgtgacta cctcatccac caaggcctca cgctccctgc
    27901 gcttttcctt catcatatgg gtaatcttgt aaaactccgt tggattgaga taacggaaag
    27961 acaagtcttc taattcccat ttgacactgg aaatccccaa acgatgggca agtggggcat
    28021 agatttccat ggtttctttg gaaatacgct cctgcttgtc ttttcgaaga tgtttcaggg
    28081 tccgcatatt gtgcaagcgg tcagacagtt tgaccaaaat aacgcggatg tcctcagaca
    28141 tggccatgag catcttgcga tgattttccg ctaattgctc ctcgatcgat ttgtactcga
    28201 ccttgccaag cttggtaact ccgtcaacaa tcatccgcac atcaggacca aactctcttt
    28261 ccaaatcgtc caaagtcgca tctgtatctt ccaccacatc atgcaagaat ccacaagcta
    28321 ctgttacagc atccagcttt agcttagcta aaatacctgc cacttggata gggtgaatga
    28381 tataaggctc gcctgatttg cgatattgac cactgtggca ttcaacagca tagaccaagg
    28441 ccttatggac aaaatgaaca tcctcttccg ttaaatattc tttggttaaa gcgacaactt
    28501 cttcgcctgt taaattcact tctttcggca tctctactct ccaattcttc ctaccatttt
    28561 atcacttttt taagaatatg aaaactagat tggaacagaa taagaaaaaa ataattcaaa
    28621 attgcttgat aattctgaat tattggcccg taatatacta cgaagttaga ttttaaactt
    28681 aggtgataga aggagagata gaagaacgga aaccatattg taacccaaag actttctgac
    28741 ttccccaatt ccattgaaga tacgaaagat aaacggtgga actcgtatca catacactgg
    28801 taccttgact ggattttgga attaatacta aatgaaaatc aaagagcaaa ctaggaaact
    28861 agccgcaggt tactcaaagc accgctttga ggttgtagat aagactgaca aagtcagtca
    28921 catatatacg gcaaggcgac gttgacgcgg tttgaagaga tttttgaaga gtataaaaat
    28981 cctcaagata ctttcttcta tcctttagtt tataaggaga atacctatga aaaaactgct
    29041 atttctatct ttgctctcct aacgttagga gtttgctgcc tgttcttatt cagccagcaa
    29101 agctataaaa aacagtcgtt caatactatg ctaacgacca gaacctgccc agtaggataa
    29161 cttatagtga gtatagcgac aaatgtgaag ccaactacgg tagcactcta aacatcacgt
    29221 ctatcaaaca agctaatgac ggagtttatg caacctatga agggcaattg acacctttcc
    29281 aatattgata aattgataac cagcctgtct tcatctagtc atgctggttt ttaagttcat
    29341 tttaaatcct tacctattct ccctaactgt gctatactta atttatactc aatgaaaatc
    29401 aaagagcaaa ctagaaagct agccgcaggc tgttcaaagc actgctttga ggttgcagat
    29461 aaaattgacg cagtttgaag agattttcga agagtattag tacattcttt gagattggag
    29521 ctagtatgaa aatccataaa accgtgaatc ctgttgccta tgaaaatacc tattatctag
    29581 aaggcgaaaa gcacctcatc gtcgtcgatc ctggtagtca ttgggaagcc attcgtcaga
    29641 caatcgagaa gatcaacaaa ccgatctgtg ctattctctt gacccacgcc cattatgacc
    29701 atatcatgag tctggacttg gtttgcgaga cgtttggcaa tcctcctgtc tatatcgcag
    29761 agagcgaagc cagctggctc tacactcctg tcgataatct ctccggtctc cctcgccacg
    29821 atgatatggc agatgtggtc acaaaacctg cagaacacac ctttgtcttt cacgaagaat
    29881 accaactaga ggaatttcat tttaaggttc tgccgacccc agggcactct atcggtggtg
    29941 tttccctagt ctttcctgat gctcacctag tcttgacggg agatgctcta ttccgcgaaa
    30001 ctatcggacg gaccgacctt ccgactggta gcatggagca actccttcat agtatccaga
    30061 cccaactctt caccctatca aactacgatg tctatccagg acatggtcca gctactacta
    30121 tcgctcacga aaaggccttc aatccctttt tctagcaaga tgatgacaat cgaaatttaa
    30181 gtaaactatc cagcaaatct ttctattaca aaaggcggct ctataatatt tgtagtgggt
    30241 aaatccacta tagatattat ggagcctatt ttattgtaga aaaaaaatcc cataagatct
    30301 ataatgaaaa gcgacaaaac aactcattag aaagaatcat atggaacaat tacattttat
    30361 cacaaaatta ctagacatta aagaccctaa tatccagatt ttagacatca tcaataagga
    30421 tacacacaag gaaatcatcg ccaaactgga ctacgacgcc ccatcttgcc ctgagtgcgg
    30481 aaaccaattg aagaaatatg actttcaaaa accttctaaa attccttatc ttgaaacgac
    30541 tggtatgcct actagaattc tccttagaaa gcgtcgattc aagtgttatc actgttcaaa
    30601 aatgatggtc gctgaaactt ctatcgtcaa gaagaatcac caaatccctc gtattatcaa
    30661 ccaaaaaatt gcgcaaaagt taattgaaaa gatttctatg accgatattg cccatcagct
    30721 ttccatctca acttcaactg ttattcgtaa gctcaatgat tttcacttta aacatgattt
    30781 ttcttgtctt cctgagatta tgtcttggga tgagtatgct tttacaaagg gaaagatgag
    30841 tttcattgcg caagattttg ataatcttaa tattatcact gttcttgaag gcagaacaca
    30901 agctgtcatc cgaaatcact ttcttcgcta cgatagagcc gtccgatgtc gcgtcaaaat
    30961 cattactatg gatatgttta gcccttacta tgacttggct aaacagcttc gctttcaaat
    31021 ttctaggctc aggctgaaac agtctcccag actgtttcac tcccgaatgc taaaatcgtt
    31081 cttgatcgct ttcacattgt acaacatctt agccgtgcta tgagtcgtgt gcatgtccaa
    31141 atcatgaatc agtttcatcg aaaatcccat gaatacaagg ctatcaagcg ctactggaaa
    31201 ctcattcaac aggatagccg taaactgagt gataagcgat tttatcgtcc tacttttcgt
    31261 atgcacttaa ccaataaaga gattttaaac aagcttttga gctattcgga agacttgaaa
    31321 caccactatc agctctatca gctcttgctt tttcacttcc agaacaagga accagagaaa
    31381 tttttcggac ttattgagga caatcttaag caggttcatc ctctttttca gactgtcttt
    31441 aaaaccttcc tcaaagataa agaaaagatt gtcaacgccc ttcaactaca ctattctaat
    31501 gccaaactgg aagcgaccaa taatctcatc aaacttatca agcgcaatgc ctttggtttt
    31561 cggaactttg aaaactt
//
LOCUS       DAVLZS010000024        29083 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLZS010000024 DAVLZS010000000
VERSION     DAVLZS010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.024"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..880
                     /locus_tag="VYO88_001143"
     CDS             <1..880
                     /locus_tag="VYO88_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1719248.1"
                     /translation="GGKRERRKTEIVQELMTEFSLVLLLKSIKLARWTYYYHLKQLDK
                     TDKDQELKAEIQSIFIEHKGNYAYRRVHLELRNRAYLVNHKRVQGLIKVLNLQAKMRQ
                     KRKYSSHKGDVGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFN
                     SEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQ
                     ASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSLNQLEQAIVDYIDYYNNKRIKV
                     KLKGLIPVQYRTKSFG"
     gene            complement(1008..1211)
                     /locus_tag="VYO88_001144"
     CDS             complement(1008..1211)
                     /locus_tag="VYO88_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719249.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1204..2286)
                     /locus_tag="VYO88_001145"
     CDS             complement(1204..2286)
                     /locus_tag="VYO88_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1719250.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQTALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2412..3194)
                     /locus_tag="VYO88_001146"
     CDS             complement(2412..3194)
                     /locus_tag="VYO88_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1719251.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3194..4537)
                     /locus_tag="VYO88_001147"
     CDS             complement(3194..4537)
                     /locus_tag="VYO88_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1719252.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQIIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4636..5952)
                     /locus_tag="VYO88_001148"
     CDS             complement(4636..5952)
                     /locus_tag="VYO88_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1719253.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6145..7371
                     /locus_tag="VYO88_001149"
     CDS             6145..7371
                     /locus_tag="VYO88_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1719254.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7570..9144
                     /locus_tag="VYO88_001150"
     CDS             7570..9144
                     /locus_tag="VYO88_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1719255.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9409..10197
                     /gene="codY"
                     /locus_tag="VYO88_001151"
     CDS             9409..10197
                     /gene="codY"
                     /locus_tag="VYO88_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1719256.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10197..10772
                     /locus_tag="VYO88_001152"
     CDS             10197..10772
                     /locus_tag="VYO88_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1719257.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10854..10939
                     /locus_tag="VYO88_001153"
     tRNA            10854..10939
                     /locus_tag="VYO88_001153"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10888..10890,aa:Leu,seq:aag)
     gene            11222..12352
                     /gene="ugpC"
                     /locus_tag="VYO88_001154"
     CDS             11222..12352
                     /gene="ugpC"
                     /locus_tag="VYO88_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1719258.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(12499..12645)
                     /locus_tag="VYO88_001155"
     CDS             complement(12499..12645)
                     /locus_tag="VYO88_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719259.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12853..13611
                     /locus_tag="VYO88_001156"
     CDS             12853..13611
                     /locus_tag="VYO88_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1719260.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13699..14211
                     /locus_tag="VYO88_001157"
     CDS             13699..14211
                     /locus_tag="VYO88_001157"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1719261.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14393..15337
                     /locus_tag="VYO88_001158"
     CDS             14393..15337
                     /locus_tag="VYO88_001158"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1719262.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            15346..16023
                     /locus_tag="VYO88_001159"
     CDS             15346..16023
                     /locus_tag="VYO88_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1719263.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLFQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            16121..16879
                     /locus_tag="VYO88_001160"
     CDS             16121..16879
                     /locus_tag="VYO88_001160"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1719264.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16917..18422
                     /gene="lytC"
                     /locus_tag="VYO88_001161"
     CDS             16917..18422
                     /gene="lytC"
                     /locus_tag="VYO88_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV1719265.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18918..19436
                     /locus_tag="VYO88_001162"
     CDS             18918..19436
                     /locus_tag="VYO88_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1719266.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFADAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19566..20072
                     /locus_tag="VYO88_001163"
     CDS             19566..20072
                     /locus_tag="VYO88_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1719267.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            20072..20242
                     /locus_tag="VYO88_001164"
     CDS             20072..20242
                     /locus_tag="VYO88_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719268.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            20274..21506
                     /gene="clpX"
                     /locus_tag="VYO88_001165"
     CDS             20274..21506
                     /gene="clpX"
                     /locus_tag="VYO88_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1719269.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21515..22102
                     /locus_tag="VYO88_001166"
     CDS             21515..22102
                     /locus_tag="VYO88_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1719270.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGIDEAWDAILEKL"
     gene            22113..22493
                     /locus_tag="VYO88_001167"
     CDS             22113..22493
                     /locus_tag="VYO88_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1719271.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22545..23435
                     /gene="rapZ"
                     /locus_tag="VYO88_001168"
     CDS             22545..23435
                     /gene="rapZ"
                     /locus_tag="VYO88_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1719272.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            23432..24409
                     /locus_tag="VYO88_001169"
     CDS             23432..24409
                     /locus_tag="VYO88_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1719273.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            24406..25317
                     /gene="whiA"
                     /locus_tag="VYO88_001170"
     CDS             24406..25317
                     /gene="whiA"
                     /locus_tag="VYO88_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1719274.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHYQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(25351..26319)
                     /locus_tag="VYO88_001171"
     CDS             complement(25351..26319)
                     /locus_tag="VYO88_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1719275.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            26455..27312
                     /locus_tag="VYO88_001172"
     CDS             26455..27312
                     /locus_tag="VYO88_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1719276.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            27299..28078
                     /locus_tag="VYO88_001173"
     CDS             27299..28078
                     /locus_tag="VYO88_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1719277.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            28102..>29083
                     /locus_tag="VYO88_001174"
     CDS             28102..>29083
                     /locus_tag="VYO88_001174"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1719278.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQS"
BASE COUNT         8682 a         5338 c         6569 g         8494 t
ORIGIN      
        1 aggaggaaaa agagaaagaa gaaagacaga aattgttcaa gaattaatga ctgagttttc
       61 gttagttctt cttctaaaat ccattaaact agctcgttgg acctactact atcacttgaa
      121 acagctagac aaaacagata aggaccaaga gcttaaagct gaaattcaat ccatttttat
      181 cgaacacaaa ggaaattatg cttatcgccg ggttcattta gaactaagaa atcgtgctta
      241 tctggtaaat cataaaagag ttcaaggctt gataaaagta ctcaatttac aagctaaaat
      301 gcgacagaaa cgaaaatatt cttctcataa aggagacgtt ggtaagaaag cagagaatct
      361 cattcaaggc caatttgaag gctctaaaac aatggaaaag tgctatacag atgtgacaga
      421 atttgccatt ccagcaagta ctcaaaagct ttacttatca ccagttttag atggctttaa
      481 tagcgaaatt atcgcctata atctttcaac ttcacccaac ttagaacaag tacaaacaat
      541 gttggaacag gcattcacag agaagcacta cgagaatacg attctccata gtgaccaagg
      601 ctggcaatat caacacgatt cttatcatca gtttcttgag ggtaagggaa ttcaagcatc
      661 catgtcacgc aagggaaaca gccaagacaa cggtatgatg gagtccttct ttgggattct
      721 gaaatcggaa atgttttatg gctatgagaa aacatttaaa tcacttaatc aattggaaca
      781 agctattgta gactatattg attactacaa caataaacga attaaggtaa aactaaaagg
      841 acttatccct gtgcaataca gaactaaatc cttcggataa attaattgtc taactttttg
      901 gggggcagtt cattctacac ccactattat gcgttttatt gtgggaagat tttcctcatt
      961 ttctagtgaa attgaacttt ttctaacatc ttttgataga tgacttctta atcaattatc
     1021 atttccattg ttgtttcttg gggtttcatc ccttgtcttt gataaaagcg gagagcaccc
     1081 tcgttatcat tccagacact tagggttaga ttattgcagc caatttcttt agcataatag
     1141 cagaaaaatg acaataaaat agcccctaga tattttgaaa ggaaagcata ggggctatat
     1201 agtttaatca aaataaagca aatctttgct ggtgcttgta aagaggtcga agccatcctt
     1261 ggtaacaaca ccgcagtctt caatacgaac accgacttta ccagggatat agatacctgg
     1321 ttcaacagag aagcacatgc cttcttcgat gaccatgtcg tttccttcca tgatagatgg
     1381 gaattcatgg acatccatac cgataccatg tccgagacgg tggttgaagt actcaccata
     1441 accagctttt tcgatgacct cacgggcagc gcggtccact tcatgagcag tcacacctgg
     1501 cttgataaag tcaagagcag tttgttgggc ttcaagagtc aagttgtaaa tatctttctt
     1561 gaattggtct ggtttgccga cagcgactgt acgagtcata tctgacgcat agccattgac
     1621 cagaacaccc aggtcaaaga ggagaagagc atcattttca accttattag ctgctggaat
     1681 gccgtgtgga ttcgcagcat tatcaccagt caagaccatg gtatcaaagc tcatttcgta
     1741 accttcacgt ttcatggcaa agtcaatttg tgcgatgata tctgtctcag tcttatcaag
     1801 agaaatattg tcaaaaccaa catgaacagc cttgtcagca taaagacctg caaccatcat
     1861 tttttgtact tcatcagctg atttgatgag gcgcatgcgt tggatacgag gagtgaggtt
     1921 ttcaaactca gcagtttcaa aaactgtttt caaaccatgg tatttggtca agatgagatt
     1981 gtcaaactca acagcgacac gtttgaagtc aagttgtgga agagcatgtt tgattttttg
     2041 ccatggattt tcagaatcga catagcccac tactgggaag gaaacggtgc tacttgcacg
     2101 ttctacttca agagctggga caaagaggag aggttcctga tccgctagga caaagaggaa
     2161 catttggcgt tcatggggat cactgtaaaa accagtgagg taattgattg tgacggggtc
     2221 agatacgaca gcgacgtcta gtttttctga ttcaagatat gttaggattt gttgtaattt
     2281 agacatatgc taccttcttt ctacccctct attttggcaa aaaatgagag aaaatgcaag
     2341 ggagaagggt aaaagaaaag acaaaaaact ccgacaagat aacggagttc tttgatatca
     2401 ttttcctttg tttaagaaaa gtcagccttg cttttgacgt cactgtactc ttcagcgatt
     2461 tcttggctga ggatatcctc ataggcaggg agttggatat cctgaccata tttcttcttg
     2521 agggcagtag taactaggcg ataagccaga ttggcattac gagagaggat aggcccgtgg
     2581 aagtaggaac caaagacatt cttataatga accccttcac cgaccttttc ttcgttgttt
     2641 ccatttccat agacaacctg tcccagcggt ttttggtcat cagagaggaa ggtacggcct
     2701 tggtgatttt caaatccata gtaggtttca tcgaaatctt cattgtgaat cttgatgtca
     2761 ccgataaaac ggttattggt ctggttgagc gtgtagtgtc ccatgacccc tagcccttcg
     2821 atacgttttc ctgaagcttc aacataatat tgacccaata gttggaaacc accgcagata
     2881 gccagaacta caccgtcgtt ttggatgtag ttgtcaatgc tctctttttt agcaggtagg
     2941 tcgtctgcaa tgatactttg ttcaaagtct tgaccaccac cgaaaaaggc gatgtcgtag
     3001 tgattttcat caaagtcatc atggagagaa acgatgtcaa cggtcacatg ggctcccagt
     3061 ttttcagcca catacttgag catgaggatg tttccattgt ccccgtaggt attcatgaga
     3121 tttccgtaga ggtgggcaat gttgagctga taggggtaat tgccatcttt tgaggaaagt
     3181 gaagtataaa ccattagttc atctcctttc taacaatctg acgactagcc agcagttcac
     3241 gaaattccag catggcagta taagttgcca gaatataggc atgcttgcag tcttgattct
     3301 caatggtctt gagaacttgc tccagattac tcgtttcagt gattttctca gctggatagc
     3361 cagtcactcg gaggcgacga gcgatttcag aatgacgaac accgccagcg ttgatttcag
     3421 gaatgtccat gtcagtgatt tgctcaaagt ctgcatccca gatccagcta gtgtcaattc
     3481 catctgcata gttggcatta aggaggacag ataggctaaa tggataaggt gctagtttga
     3541 tcatttcgat agcttgggtt gcaccgactg gatttttaat caagacaagg gtacattcct
     3601 tgtcaccgat atgaaaggtt tcttggcgtc caaagacagc acggctcttg tcaaatccct
     3661 gtttgatgat ttgcgaatcg gcacctagga aacgggcgat ggccacagca gctagggcgt
     3721 tatagatatt atagagcccg ccgatttgga taccgtattc ttggccgtct atgacaaagc
     3781 gagagcgatt gttggtcaac tcaaccaatt ttgtcaaacg atagtcgaga tcaggacgtt
     3841 tacatccaca accttcacag atataggcac ccaagtttgc ataggtatta tgctcatatt
     3901 tgaggatgcc ttggcagtca ggacagagaa tcccttcggt attgtagtga gccagttggg
     3961 ctggtccttt ttccaagtca aaaccaaaat actctatagg gtttggaata gttggcttgt
     4021 agaaaagtgg actgtctccg ttaaggagaa cagtagcagt tggaactttc cgaatggcat
     4081 ccaatatcat gttataggta gtatagattt caccgaaacg gtccatctgg tcacggaaga
     4141 tattagtaat gacaaaaaga ctaggctgga tatagtcaca gatacgagat agactggctt
     4201 cgtcgatttc taggacggca atatttttcc cagttttaga agatttggct gttaagaagg
     4261 ttgtcgcaat tcctgtaatc atgttggcac cgcttgggtt ggtcagaact tgaccataaa
     4321 cttcttttaa aataccgaca gtgagggcag ttgtcaaggt ttttccgttg gttccagtga
     4381 ccacgacaat ctcgtagttc ttagctaggt tttgtaaaat atctttatca aattgaaggg
     4441 cgactttacc tgggagcgta cttccacggc caagacggct taaaatgaag tgggaagaac
     4501 gcccagcaag aaggcccaaa gtagttttta agttcatgtt tctattatat cataaaagag
     4561 gagaaagaca gatttgagat tccgcagaag taaaaacagc ccaaagaggg ctgttcgata
     4621 cgattaaatc tcaacttaaa tcgcaaacaa gtcattcaag ttctcagcca aggttgggtg
     4681 agtgaagatt tgttttgtga agtaagtgta aggaatcttg ttgtccatag caacagtgat
     4741 gatgttgatg atttcttgag aaccttctga gaagatgctt gctccaagaa tttcttttgt
     4801 ttcagtattg acaacagctt tgaaggcacc gcgaaggtct ccatttacgt gaccacgagg
     4861 cattgctgca acggggattt ccttaacagc gtatggaagt ttcaaatcag ctgcttggct
     4921 ttcagtcaaa ccaacttgtg aaagtgcagg tgtgatgaac atagtatttg gcacattgag
     4981 acggtcttca agtgtgtagc tgccatctcc agcaaggtag ctgtaaacaa cacggaagtc
     5041 atcaagtgaa atgtaagtaa attgaaggcc accgttgaca tctccaactg caaagacacc
     5101 aggaacgttt gtttgacagt gtttgtctac tttaatagca ccacgttcag ttagttcaat
     5161 atctgtattt tcaagttgaa gtggttctac atttggtttg cgtccagttg cgtagagaag
     5221 ggcgtcgaaa cggtaagttt cgtcttcagt tacgacaagc acttggtcac catcgttttt
     5281 gatttcagta gtatggatat tttgaagcaa ttcaatgcca tcttcttcca ggtattgttt
     5341 agcaagagct gcgatggaag gttctgcacg aggaaggaaa gtatccaagg catctaggac
     5401 tgtgaccttg cttccaagtt tgttgtaaag gccggcaaat tcaagaccga tatttccgcc
     5461 accaaggatt ccaagttttt caggtaattt gtccaagttt tggatacctg ttgagtcaaa
     5521 gatgtttttg cttgtagcaa gtccagggat tggcaagacg tttgaaacag caccagtgtt
     5581 gatgacgatt gtttcagcag tcagttcttt cttttcatca ccagcttgga tttcgatgac
     5641 tttatttgaa aggaagtgag cttccgcatc aaagatatct acgcctgtac cagcaacagt
     5701 cgcatagttt ttaccgttga ggcgaccagt gatcgtgttt ttagtagcaa tcacttcttc
     5761 aaaagacaag tccttttcag cagcaactag caaggtttta gttgggatac aaccaatgtt
     5821 gatacaagtt ccaccgtaca tagccttgct gcgttcaacg agggcaactt ttttgccagc
     5881 tgaagccaat ttacctgcta gtgttttacc agctttacca aatccaataa caattaaatc
     5941 gtatgttaac atttatcttc ctcctattcg aattacattc tagcacaaga aaaaaacttt
     6001 tgcacaattc tgctacggaa aagacagaaa aagataaaaa cgctttccag acaaaaaact
     6061 agtaattttt tgacaagctt gataaactaa aatcctatct atttttatat aagatagaat
     6121 aaatgttcga aaataggagg ttttatgaaa tcgaatcgtt atattattgc ctttgctggg
     6181 gtcattttac acttaatgct gggttcgact tatgcttgga gtgtttatcg taaccctatt
     6241 attgaaaaaa cgggatggga tcaggcttct gttgcctttg cctttagtct agcaatcttt
     6301 tgtttgggct tatcggctgc atttatgggg cgtttggtag aaaaatttgg tccgagagtc
     6361 atggggagtc tatctgcttt tctatacgca ggtggaaata tcttaacagg atttgcaata
     6421 gaccgtcagg agctgtggtt gttgtatctc gcttatggca ttttaggtgg gcttggtttg
     6481 ggagcaggct atattacccc tgtgtcgacg attataaaat ggtttcctga taaacgtggt
     6541 ctcgcaacag gtttagcgat tatggggttt ggttttgctt ctttattgac tagtcccata
     6601 gcgcaacacc tcatcgcagg ggtagggatt gtagaaactt tttatatttt aggagcaagt
     6661 tactttatta tcatgctcct agcttcacaa ttcattaagc gtccaaatga gcaagagctt
     6721 gcaattttat cttcttcagg gaaagaaaaa acagcctctt tgacgcaagg aatggctgca
     6781 aatcaggctc taaaaagcaa tcggttttat atgctttgga ttattttctt tatcaacata
     6841 gcttgtggtt taggcttaat ttcagcggca tcgccaatgg cacaggagat ggctggcttg
     6901 tctacaagtc atgcagcagt aatggtgggt gttttgggga ttttcaatgg atttggtcgc
     6961 ttgctctggg cgagtttgtc tgactatatc ggtcgccctc taacctttag tatattactg
     7021 cttgtcaatc ttttcttttc tctctcactt tggctcttta cagattccgt tttatttgta
     7081 gttgctatgt ctattttgat gacttgctat ggagctggtt tttctttgat tccagcttat
     7141 ctcagtgata tttttggaac caaggaattg gccgctctgc atggttatat tttaacagct
     7201 tgggcaatgg ctggtttagc gggacctatt ttattagcag agacttataa aatggctcat
     7261 tcgtacacac aaaccttgtt cgtttttctc attttataca gtatcgcctt ggctttgtct
     7321 tattatctag gtcgttcaat caaaaaagaa agtcaaaaac cgcttacatg attttctgta
     7381 gaaatggggc tatcttttgc tctggtcttg tgttatacta gataggttgc aaagaaaaca
     7441 gtacttttct tttgtggaaa agaagcaaca cgattttata tctagttata tgaaaatacg
     7501 tcataaaaag aaaagtataa actaagccct atagggtggc ttcgcaccac ctttagaaag
     7561 aagaataacg tgaaatttaa tgaattaaac ttgtctgctg atttgctagc agaaattgaa
     7621 aaagctggtt ttgtagaagc tagtcctatc caagaacaaa ctattccttt ggcccttgaa
     7681 ggcaaggatg ttatcggtca agctcagact ggtacaggaa aaactgcagc ctttggcttg
     7741 cctacccttg aaaaaatccg tacagaagaa gcgactatcc aagccttggt catcgctcca
     7801 actcgtgaac tagctgtcca aagtcaagaa gaactcttcc gctttggtcg tagtaaggga
     7861 gtcaaagtcc gttcagtata tggcggatca agcattgaaa aacaaattaa ggctcttaaa
     7921 tctggtgccc atattgtggt gggaactcca ggtcgcctct tggacttgat taaacgcaag
     7981 gccttgaaat tacaagacat tgaaaccctt atccttgacg aagcggatga aatgcttaac
     8041 atgggcttcc ttgaagacat cgaagccatt atttcccgtg tacctgagaa ccgtcaaact
     8101 ttgcttttct cagcaactat gccagatgcc atcaaacgta tcggtgttca gtttatgaaa
     8161 gcccctgaac atgtcaagat tgcggctaag gaattgacaa cagaattggt tgaccagtac
     8221 tatatccgtg ttaaggaaca agaaaaattt gacaccatga ctcgtctcat ggatgtggca
     8281 caaccagaac tcgctattgt atttggtcgt accaaacgcc gtgtggatga attgactcgt
     8341 ggtttgaaaa ttcgtggctt ccgtgcagaa ggaattcatg gcgacctaga ccaaaacaaa
     8401 cgtcttcgtg tccttcgtga ctttaaaaat ggcaatcttg atgttttggt tgcgacagac
     8461 gttgcagcgc gtggtttgga tatttcaggt gtgacccatg tctacaacta cgatattcca
     8521 caagatcctg agagttatgt tcaccgtatc ggtcgtacag gtcgtgctgg taagtcaggt
     8581 caatctatta cttttgttgc tccaaacgaa atgggttacc ttcaaatcat tgaaaacttg
     8641 actaagaaac gcatgaaagg tctcaaacct gcaagtgtag aagaatcctt ccaatcaaaa
     8701 aaacaggtag ctctcaagaa aatcgaacgt gattttgcag atgaaaccat tcgtgccaac
     8761 tttgagaaat ttggtaagga tgctcgcaaa ttggctgctg agtttactcc agaagaattg
     8821 gcaatgtata tcttgagtct gacagtccaa gacccagata gccttccaga agtggagatt
     8881 gcacgtgaaa aaccactacc gtttaaacca tcaggtaatg gtttcggtgg taaagctaag
     8941 ggaggtcgtg gaggccgtcg tggggacgac cgtcgagagc gtgatcgtcg tggcaatggt
     9001 cgccgtgatg agttcaaaaa aggaagtcgt ggcaacgatc gttttgataa ggaaaaacgt
     9061 taccgtaagg ataataaaaa accacgcaat actttaagcg aaaagcaaac aggctttgtt
     9121 attcgtaaca aaggtgataa ataagaaaaa gcggttcaaa atgaatcgct tttttatata
     9181 aggagaccga atgtgaaaaa gacaaataaa attattatat tatcttttat aatattatga
     9241 tacacaaaaa taggcgactt gtcaatagaa aaggaacaat ttaattaaaa atattctggt
     9301 ttttaattaa attgtaagtc aatgcaagtc aataaggaat tttcagataa ttattgaaaa
     9361 agagacgttt ttatgttata atgatagcga ttaaattcga ggtgaaaaat ggcacattta
     9421 ttagaaaaaa ctagaaaaat tacatcaatt ttgaaacgct cagaggagca gttgcaggat
     9481 gagctccctt acaacgctat tacgcgtcag ttagcggata ttattcattg caatgcctgc
     9541 attatcaata gtaagggacg tctgcttggc tattttatgc gttataaaac aaatacagat
     9601 cgcgtagagc aattcttcca aactaagatt ttcccagatg actacgttca aggggctaat
     9661 atgatttacg aaacagaagc aaacttgcct gttgagcatg atatgagtat tttccctgtt
     9721 gagagtagag atgattttcc agatggcttg acgactattg caccgattca tgtatcgggg
     9781 attcgccttg gttctttgat tatttggcgt aatgataaaa aattcgaaga tgaggacttg
     9841 gttcttgttg agattgccag taccgttgtt gggattcagc ttcttaactt ccaacgtgaa
     9901 gaagatgaga aaaatattcg tcgtcgtact gctgtcacca tggcggtcaa taccctttct
     9961 tactccgaac tccgtgctgt ttcagcaatt ttaggggaat taaatggaaa tgaagggaag
    10021 ttgactgcgt cagtgattgc agatcgtatc ggaatcactc gctctgtgat tgtcaatgct
    10081 cttcgtaaac ttgagtctgc ggggattatt gaaagtcgct cacttggaat gaagggaacc
    10141 tatcttaagg tcttgatttc agatattttt gaagaagtga agaaaagaga ttactaatga
    10201 caaaggcttt aatttcgatt gattatacag aagattttgt tgctgatagt gggaagctga
    10261 cagcaggtgc tccagctcag gcgatttcgg atgccattag caaggtaact cgattagctt
    10321 ttgaacgagg agattatatc ttctttacta ttgatgctca tgaagaaaac gattgtttcc
    10381 atccggaaag taagttattt cctcctcata atctgattgg gacgagtgga cggaatttat
    10441 atggagattt ggggatcttt tatcaagagc atggttcaga cagtcgtgtc ttttggatgg
    10501 ataaacgcca ttactcagct ttttcaggga ctgacctaga tattcgtttg agagagcgta
    10561 gagtgtctac cgttatctta acaggtgtct tgacggatat ctgtgtccta catacagcta
    10621 tagatgccta taatctagga tatgacatcg agattgttaa accagctgtt gcttccatct
    10681 ggcctgaaaa tcatcaattt gccctaggtc atttcaaaaa tacactcgga gctaagttag
    10741 tagatgaaaa tctaaatgaa ctttctgagt aacctggttg gtgaaaatga aaaaatttga
    10801 aaaaaagtgt tgacaagcat cccaaaagtt gatatactag taaagtaatc gacgcgggga
    10861 tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg tcgtgagggt
    10921 tcaagtccct ctctccgcat aggaaaagag ttagctaaag ctagctcttt tgtatttctc
    10981 taaaaaatta gaatccagtc aaatgtagtg gagaatcagc gaaaatatgg gaaaactgat
    11041 ccttgtttct gcttttgtca tagaagaata ataaagatta tcttcttcaa attctccgat
    11101 attctctaaa gttttgtgca agttgcacag aactttttta tttttttggt catcttgcca
    11161 tagaaatata aagcgttttc atctataata taattatcaa aaaacaaaag gagttcacct
    11221 catggtagaa ttgaatctta aaaatattta caaaaaatat ccaaacagcg aacactattc
    11281 agttgaagat ttcaacttga acatcaaaga taaagaattt atcgttttcg taggaccttc
    11341 aggatgtggt aaatcaacta cactccgtat gattgctggt cttgaagaca ttacagaagg
    11401 tactgcatct atcgatggcg tggttgtcaa cgacgtagct ccaaaagacc gtgatatcgc
    11461 catggtattc caaaactacg ctctttaccc acacatgact gtttatgaca acatggcttt
    11521 cggtttgaaa ttgcgtaaat acagcaaaga agacattaac aaacgtgttc aagaagcagc
    11581 tgaaatactt ggattgaaag aattcttgga acgtaaacca gctgaccttt caggtggtca
    11641 acgtcaacgt gttgccatgg ggcgtgcgat tgtccgtgat gcgaaagtat tcttgatgga
    11701 cgaacctttg tcaaacttgg atgccaaact tcgtgtatca atgcgtgctg aaatcgctaa
    11761 aattcaccgt cgtatcggag ctacaactat ctatgtaact cacgaccaaa cagaagcgat
    11821 gacacttgca gaccgtatcg ttattatgtc agctactaag aaccctgctg gtacaggtac
    11881 tatcggacgt gtagaacaaa tcggtactcc tcaagaagtt tacaaaaatc cagttaacaa
    11941 attcgttgca ggattcatcg gaagcccagc tatgaacttc atcaacgtga aattggttgg
    12001 tagcgaaatt gtttctgacg gtttccgttt gaaagtgcca gaaggagcat tgaaagttct
    12061 tcgtgaaaaa ggctacgaag gaaaagaatt gatctttggt atccgtccag aagacgtgaa
    12121 tgcagaacct gctttccttg aaacattccc agactgtgtt gtaaaagcga ctatctctgt
    12181 atcagaactg cttggttcag aatctcacct ttactgccaa gttggtaaag acgagtttgt
    12241 tgcaaaagtt gatgctcgtg actacttgca aacaggtgca acagttgagc ttggatttga
    12301 cttgaacaaa gcacacttct tcgatgtaga aactgaaaaa acaatctact aaaataaata
    12361 aaattcaaag cactacaaga aaagatatct ctttatcaat tgtagtggag agatatcagt
    12421 taatctaggg agagaaacaa aatgcttctc tcctttttgc tagggaagtc atattatgca
    12481 tctatattgt gatgctcttt aatactcttc gaaaatctct tcaaaccacg tcaacgtcgc
    12541 cttgccgtac gtatgattac tgatttcgtc agttttatct gcaacctcaa agatgtactt
    12601 tgagcagctt acggctagtt tcctagtttg ctctttgatt tccattgagt attatttgtg
    12661 ggtaccatct acaagtgaag ctatatgcgt aaactacatg agcaattgaa ttcgaactag
    12721 agaggtaata ataaatttat gctatagtta tggtgacttg tatgcttttg attctagttt
    12781 atcaaataat agattagaat tgtcagataa tatcattttg tgttataatg aagaaaaaac
    12841 agaggtgttc aaatgtcaga agcaggtcat aagtttttag caaaattggg gaaaaaacgc
    12901 ttacgtccag gtggaaagcg tgccacagat tggttaattg cagaaggagg attttcaaaa
    12961 gaaaagagaa tactagaggt tgcgtgtaat aggggaacta cagcaattga gttggcacag
    13021 cgttttggtt gcaagataac tgctgttgat atggatgctc aagctttaga agtggctaaa
    13081 aaatctgctg gaacggcagg tgttgctcat ttaatcagtt ttgaaagagc aaatgcaatg
    13141 aaacttcctt atcaagatgc tagttttgat attgttataa atgaagctat gctgactatg
    13201 caagccgatc aagctaagaa aaaatgtgta atggaatatc taagggtatt aaaacctgga
    13261 ggtcttctct tgacacatga tgtgcttctt aaggaagcta aagagtctat cagacaggaa
    13321 ttatcacaag caattcatgt aaatgtaggt cctttaactc aagatggttg ggaacaggtg
    13381 atgatagaat caggttattg tgatgtgaaa gcattgactg gtgaaatgac attaatgaaa
    13441 ttatcgggta tgatttatga cgaaggttgg ctaggaactt tgaaaatttg tgtaaatgct
    13501 tgtaaaaagg agaatagaaa gcagttttta actatgtata aaatgtttgc taagaataaa
    13561 cagaaattgg gctttattgc gatggctagt tataaatcgt caaaacgtta gataattatt
    13621 gaagttaact tttccttttt tctttcttaa aaaatatgct ataatagaga gtaaaaaact
    13681 ttgaaagaaa gaaaaaagat gaatttaaaa gattacattg caacaattga aaattatcca
    13741 aaggaaggca ttaccttccg tgatattagt cctttgatgg ctgatggaaa tgcttatagc
    13801 tacgctgttc gtgaaatcgt tcagtatgct actgacaaga aagtcgacat gatcgtggga
    13861 cctgaagctc gtggatttat cgtgggttgt ccagttgcct ttgagttggg aattggtttt
    13921 gcgcctgttc gtaagccagg taaattgcca cgcgaagtta tttctgctga ctatgaaaaa
    13981 gagtacggtg tcgatacctt gactatgcac gcggatgcca ttaagccagg tcaacgtgtt
    14041 cttattgtag atgacctttt ggcgacaggt ggaactgtta aggcaactat cgagatgatt
    14101 gaaaaacttg gtggtgttat ggcaggttgt gccttccttg ttgaattgga tgaattgaac
    14161 ggccgtgaaa aaattggtga ctacgactac aaagttctta tgcattatta atgaaaacag
    14221 tccctagggc tgttttctct acactaggat ataaaaatag actataacta gttagagaaa
    14281 aactataatt gaaaactata tcttcttgca gtataataaa aggactaagt gtttgagatt
    14341 tgtcttcaaa catatgcaat tattcctgaa agagtacagt taggagaggg ttatgccgat
    14401 tcgaattgat aaaaaattgc cagctgttga gattttacgg acagagaata tctttgtcat
    14461 ggatgatcaa cgtgctgccc accaagatat ccgtcctttg aagattttaa ttttaaatct
    14521 catgccacag aaaatggtca cagagaccca gttgttgcgc cacttggcta atacacccct
    14581 acaactggat attgattttc tctatatgga gagccaccgt tctaaaacaa ctcgttcaga
    14641 gcacatggag accttctata aaacttttcc tgaagtcaag gatgagtatt ttgatgggat
    14701 gatcatcacg ggtgctccag ttgagcattt accatttgag gaagtggact attgggagga
    14761 atttagacag atgcttgagt ggtctaagac tcatgtctat tcgacccttc atatctgttg
    14821 gggggctcag gctgggcttt atctgcgcta tggtgtagaa aaataccaga tggacagtaa
    14881 gctatcaggt atttatcctc aggacaccct aaaagagggt caccttctat ttagaggctt
    14941 tgatgatagc tatgtatccc ctcattcacg gcacacggag atttctaagg aagaggtctt
    15001 aaacaagacc aatctcgaga ttttatcaga aggacctcag gttggggttt ctattttggc
    15061 cagtcgtgat ttacgagaaa tttatagttt tggtcatttg gagtatgacc gtgatacctt
    15121 ggcaaaagag tattttcgag atcgtgatgc aggtttcgac ccacatattc cagaaaatta
    15181 ctttaaagat gatgatgtta atcaggtacc ttgtctttgt tggtcttcat ctgcagccct
    15241 ctttttcagt aattgggtaa accatgcggt ctatcaggag acgccttttg attggagaaa
    15301 gatagaagat gatgcatctg catatgggta tttataagag gaattatgac atatttagac
    15361 gcttttaaat caggtacctt ggttttaccg agtgccctgc tcttgcattt taaggaactc
    15421 tttccttcta gcgacgattt tctggtttgg caatttttct atttgcaaaa tacgacaggc
    15481 ttagaagaaa tgtcgccaag ccagattgct gaaaggattg gcaaggaaat ttcggatgtc
    15541 aaccagtcca tttctaatct gacggaaagg ggactgttcc agtatcgtac tatcgaatta
    15601 aatggcgaaa ttgaattgct ctttgatgct agtttggcct tggaacgttt ggatgacctg
    15661 tttggagcag ttcattcaag ttcagaccag ctaacacctc aaaaccagct caaggatttg
    15721 gtggaaacct tccagcagga gttgggacga ttgttgacgc cttttgagat tgaggatttg
    15781 accaagacac taaaggaaga tggaaccagt gctgacttga ttaaggaggc tcttcgtgaa
    15841 gctgttttga atggaaaacc aaactggaag tacattcagg cgattttgag aaactggcgc
    15901 catgaaggaa tcaagagtgt ggctcaaatt gaggccaaga gagcagaaag agaagcaagc
    15961 aatcctcagt tgacacaggt atctgcagat ttcagaaatg ccatggatct ctggaaggat
    16021 taatccatgc aagtaggctt gaaatccgag taagatttgc aagctgtgta taattgtgat
    16081 agaataaata gaaaataaat tgaaaaaaga ggtatgtgaa atgtcacgta aaccatttat
    16141 cgctggtaac tggaaaatga acaaaaatcc agaagaagct aaagcattcg ttgaagcagt
    16201 tgcatcaaaa cttccttcat cagatcttgt tgaagcaggt atcgctgctc cagctcttga
    16261 tttgacaact gttcttgctg ttgcaaaagg ctcaaacctt aaagttgctg ctcaaaactg
    16321 ctactttgaa aatgcaggtg ctttcactgg tgaaactagc ccacaagttt tgaaagaaat
    16381 cggtactgac tacgttgtta tcggtcactc agaacgccgt gactacttcc atgaaactga
    16441 cgaagatatc aacaaaaaag caaaagcaat ctttgcgaac ggtatgcttc caatcatctg
    16501 ttgtggtgaa tcacttgaaa cttacgaagc tggtaaagct gctgaattcg taggtgctca
    16561 agtatctgct gcattggctg gattgactgc tgaacaagtt gctgcctcag ttatcgctta
    16621 tgagccaatc tgggctatcg gtactggtaa atcagcttca caagacgatg cacaaaaaat
    16681 gtgtaaagtt gttcgtgacg ttgtagctgc tgactttggt caagaagtcg cagacaaagt
    16741 tcgtgttcaa tacggtggtt ctgttaaacc tgaaaatgtt gcttcataca tggcttgccc
    16801 agacgttgac ggtgcccttg taggtggtgc gtcacttgaa gctgaaagct tcttagcttt
    16861 gcttgacttt gtaaaataat cagtaagtag caaaagctag gtggaacagc attcagatgt
    16921 ctgttacatt ttttatagga gagcaaagat tgaaaacaaa aattggatta gcaagtatct
    16981 gtttactagg cttggcaact agtcatgtcg ctgcaaatga aactgaagta gcaaaaactt
    17041 cgcaggatac aacgacagct tcaagtagtt cagagcaaaa tcagtcttct aataaaacgc
    17101 aaacgagcgc agaagtacag actaatgctg ctgcccactg ggatggggat tattatgtaa
    17161 aggatgatgg ttctaaagct caaagtgaat ggatttttga caactactat aaggcttggt
    17221 tttatattaa ttcagatggt cgttactcgc agaatgaatg gcatggaaat tactacctga
    17281 aatcaggtgg atatatggcc caaaacgagt ggatctatga cagtaattac aagagttggt
    17341 tttatctcaa gtcagatggg gcttatgctc atcaagaatg gcaattgatt ggaaataagt
    17401 ggtactactt caagaagtgg ggttacatgg ctaaaagcca atggcaagga agttatttct
    17461 tgaatggtca aggagctatg atgcaaaatg aatggctcta tgatccagcc tattctgctt
    17521 atttttatct aaaatccgat ggaacttatg ctaaccaaga gtggcaaaaa gtgggcggca
    17581 aatggtacta tttcaagaag tggggctata tggctcggaa tgagtggcaa ggcaactact
    17641 atttgactgg aagtggtgct atggcgactg acgaagtgat tatggatggt gctcgctata
    17701 tctttgcggc ctctggtgag ctcaaagaaa agaaagattt gaatgtcggc tgggttcaca
    17761 gagatggtaa acgctatttc tttaataata gagaagaaca agtgggaacc gaacatgcta
    17821 agaaaatcat tgatattagt gagcacaatg gtcgtatcaa tgattggaaa aaggttattg
    17881 atgagaacga ggtggatggt gtcattgttc gtctaggtta tagcggtaaa gaagacaagg
    17941 aattggcgca taacattaag gagttaaacc gtctgggaat tccttatggt gtctatctct
    18001 atacctatgc tgaaaatgag accgatgctg agaatgacgc taaacagacc attgaactta
    18061 taaagaaata caatatgaac ctgtcttacc ctatctatta tgatgttgag aactgggaat
    18121 atgtaaataa gagcaagaga gctccaagtg atacagacac ttgggttaaa atcatcaaca
    18181 agtacatgga cacgatgaag caggcgggtt atcaaaatgt gtatgtctat agctatcgta
    18241 gtttattaca gacgcgttta aaacacccag atattttaaa acatgtaaac tgggtagcgg
    18301 cctatacgaa tgctttagaa tgggaaaacc cttattattc aggagaaaaa ggttggcaat
    18361 atacctcttc tgaatacatg aaaggaatcc aaggtcgcgt agatgtcagc gtttggtatt
    18421 aagcgatgat ttgaaagagg gatgtgatag tagcaccctc tttttctttg ttttatgata
    18481 gttcatcctc gagtaaattc aagatcttgc tcggaaatga agcttatata gtagattgaa
    18541 tatagacaaa taccttgtga ttggtaaaac attttagaaa ttcatttacc tttcctaatc
    18601 gacttggttt catcttattt caatctatta tagtattggg gaatttcttc aaaccacatc
    18661 agcttggtca gttctacctg cgacctcaaa acttgtgctt tggtcaagct gggtttagtt
    18721 tcctagtttg ctgatggatt tccattgact ataagcatcc aaccctcttt ttgtcttcta
    18781 aagaattctt aaattatcag tctattgcaa cttttctcat ataagttctt tgtcttgcta
    18841 ttggttttcc ttagtagtat actaaggtag taatcattaa gaagtggtta caaaaaataa
    18901 tgaatgaggt aaagaaaatg gtagaattga aaaaagaagc agtaaaagac gtaacatcat
    18961 tgacaaaagc agcgccagta gcattggcaa aaacaaagga agtcttgaac caagctgttg
    19021 ctgatttgta tgtagctcac gttgctttgc accaagtgca ctggtatatg catggtcgtg
    19081 gtttccttgt atggcatcca aaaatggatg agtacatgga agctcttgac ggtcaattgg
    19141 atgaaatcag cgaacgcttg attacactcg gtggaagccc attctctaca ttgacagagt
    19201 tccttcaaaa tagtgaaatc gaagaagaag ctggtgaata ccgtaatgtt gaagaaagct
    19261 tggaacgtgt tcttgttatc taccgttact tgtcagaact tttccaaaaa ggtttggatg
    19321 tcactgatga agaaggtgac gatgtgacaa acggtatctt tgcagacgct aaaactgaaa
    19381 cagataaaac aatttggatg cttgcagccg aacttggaca agcacctggt ttgtaagaaa
    19441 taaggaaaca tagataaatc tgtaggaaat ttcttacaga ttttttctat tttgtaagct
    19501 attccaaacc agtctttttt tgagtttttt gataaaatag tactatcagt gaaaaggatg
    19561 gaagcatgac taagaaaatc gtagctattt gggcccagga tgaagagggt gtgattggta
    19621 aggaaaatcg tctgccttgg catttgccag cagaattgca gcactttaaa gaaacaactc
    19681 tgaatcatgc tatcttgatg gggcgtgtga cctttgatgg gatggggcgt cgcttgcttc
    19741 caaaacggga aaccctgatt ttgacgcgta atccggaaga aaagatagat ggggttgcta
    19801 cttttcagga cgtccagtct gttcttgact ggtatcagga tcaagaaaag aatctctaca
    19861 ttatcggtgg gaagcaaatt tttcaggctt ttgaacctta ccttgatgaa gtgattgtca
    19921 ctcacattca tgctcgggtg gaaggagata cctatttccc tgaagagctt gacttgtctc
    19981 tttttgagac agtttcaagc aaattttacg ccaaagatga gaagaatcct tatgatttta
    20041 ccatccaata ccgcaagaga aaggaagtct aatggaacgg agtttatttg gtctattcac
    20101 ggcttttctg tgtttcatct gctttctggc aggagcacaa gcttttcgta aaaagcgtta
    20161 cgggctttct atcctccttt ggttaaatgc ctttaccaat ctggtcaata gtattcatgc
    20221 tttttacatg accttatttt agatagaatg acagtataga atggaaggaa atcatgtcta
    20281 caaatagaaa aaatgatatg atggtttatt gctcattttg tggcaaaaac caagaagaag
    20341 tacaaaaaat aattgctggc aacaatgctt ttatttgtaa tgaatgcgtg gagttagctc
    20401 aggaaatcat tcgagaagaa ttggttgagg aagtcttggc agacttgtct gaggtgccaa
    20461 aaccaattga actcctccat atcttgaacc actatgtaat tggtcaagat cgtgccaagc
    20521 gtgccttggc agtggcggtt tataaccact acaaacgcat caatttccac gatacacgcg
    20581 aagagtcaga agatgtggat ttgcagaagt caaacatttt gatgattggc ccaactggtt
    20641 cagggaaaac tttccttgcc cagaccttgg ctaagagctt gaatgtacct tttgctattg
    20701 cggatgcgac agctctgacg gaggctggtt atgtgggtga ggatgtggaa aatatcctcc
    20761 tcaaactctt gcaggttgct gactttaaca tcgaacgtgc agagcgtggc attatctatg
    20821 tggatgaaat tgacaagatt gccaagaaga gtgagaatgt gtctatcaca cgtgatgttt
    20881 ctggtgaagg ggtgcaacaa gcccttctca agattatcga gggaactgtt gctagcgtgc
    20941 cgcctcaagg tggacgcaaa catccacaac aagagatgat tcaagtggat acaaaaaata
    21001 tcctcttcat cgtgggtggt gcttttgatg gtattgaaga aattgtcaaa caacgtctgg
    21061 gtgaaaaagt catcggattt ggtcaaaaca ataaggcgat tgacgaaaac agctcataca
    21121 tgcaagaaat catcgctgaa gacattcaaa aatttggtat tatccctgag ttgattggac
    21181 gcttgcctgt ttttgcggct cttgagcaat tgaccgttga tgacttggtt cgcatcttga
    21241 aagagccaag aaatgccttg gtgaaacaat accaaacctt gctttcttat gatgatgttg
    21301 agttggaatt tgacgacgaa gcccttcaag agattgctaa taaagcaatc gaacggaaga
    21361 caggggcgcg tggacttcgc tccattatcg aagaaaccat gctagatgtt atgtttgagg
    21421 tgccgagtca ggaaaatgtg aaattggttc gcatcactaa agaaactgtt gatggaacgg
    21481 ataaaccgat cctagaaaca gcctagaggt gactatggaa cttaatacac acaatgctga
    21541 aatcttgctc agtgcagcta ataagtccca ctatccgcag gatgaactgc cagagattgc
    21601 cctagcaggg cgttcaaatg ttggtaaatc cagctttatc aacactatgt tgaaccgtaa
    21661 gaatctcgcc cgtacatcag gaaaacctgg taaaacccag ctcctgaact tttttaacat
    21721 tgatgacaag atgcgctttg tggatgtgcc tggttatggc tatgctcgtg tttctaaaaa
    21781 ggaacgtgaa aagtgggggt gcatgattga ggagtactta acgactcggg aaaatctccg
    21841 tgcggttgtc agtctagttg accttcgtca tgacccgtca gcagatgatg tgcagatgta
    21901 cgaatttctc aagtattatg agattccagt catcattgtg gcgaccaagg cggacaagat
    21961 tcctcgtggt aaatggaaca agcatgaatc agcaatcaaa aagaaattaa actttgaccc
    22021 aagtgacgat ttcatcctct tttcatctgt cagcaaggca gggatagatg aggcttggga
    22081 tgcaatctta gaaaaattgt gaggaaaaga aaatggcaaa aacaattcat acagataagg
    22141 ccccaaaggc tatcgggccc tatgttcaag gaaaaatcgt tggcaacctt ttgtttgcta
    22201 gcggtcaagt tcccctatcc cctgaaactg gggaaattgt aggagagaat atccaagaac
    22261 agacagagca agtcttgaaa aacatcggtg ctattttggc agaagcagga acagactttg
    22321 accatgttgt caaaacaact tgtttcttga gcgatatgaa cgactttgtt ccttttaatg
    22381 aggtttacca aacggccttc aaagaggaat tcccagctcg ttcagctgtg gaggtagctc
    22441 gtcttcctcg tgatgtaaaa gtcgaaattg aagtcatcgc agagattgga taagctagtt
    22501 gaagtttggt gttgccaaac ttcttttgat ataaggagaa aaagatgaca aagaaacaac
    22561 ttcacttggt gattgtgaca gggatgagtg gcgcagggaa aactgtagcc attcagtcct
    22621 tcgaggatct aggttatttc accattgata atatgccgcc agctctcttg cctaagtttt
    22681 tgcagctggt tgaaattaag gaagacaatc ctaagttggc cttggtagtg gatatgcgta
    22741 gccgttcttt cttttcagag attcaagctg ttttggatga gttggaaaat caagatggtt
    22801 tggatttcaa aatcctcttt ttggatgcgg ctgataagga attggtcgct cgttacaagg
    22861 aaaccagacg gagtcaccca ctagcagcag acggtcgtat tttagatgga atcaagttgg
    22921 aacgtgaact cttggcacct ttgaaaaata tgagccaaaa tgtggtggat acgactgaac
    22981 tcactccacg tgagctgcgc aaaacccttg cagagcagtt ttcagaccaa gaacaagccc
    23041 agtctttccg tatcgaagtc atgtctttcg gatttaagta tggaatcccg attgatgcgg
    23101 acttggtctt tgatgtccgt ttcttgccaa atccctatta tttaccagaa ctgagaaacc
    23161 aaacgggtgt ggatgaacct gtttatgatt atgtcatgaa ccatcctgag tcagaagact
    23221 tttatcaaca tttattggcc ttgattgagc cgattctgcc aagttaccaa aaggaaggta
    23281 agtccgtttt gaccattgct atgggatgta cgggtggaca acaccgtagt gtggcatttg
    23341 ctaaacgctt ggcgcaggac ttatccaaga attggtctgt taatgaaggg catcgcgaca
    23401 aagaccgcag aaaggaaacg gtaaaccgtt catgagaaaa ccaaagataa cggtgattgg
    23461 tggagggact ggaattcccg tcattctaaa aagtctgcgg gaaaaagatg tggaaatcgc
    23521 agctatcgtg acggtggcag atgatggtgg ttcttcaggt gaactccgaa aaaatatgca
    23581 acagttgaca ccgccaggtg atcttcgtaa tgtccttgtg gccatgtcgg atatgcctaa
    23641 gttttatgag aaggtctttc agtatcggtt ctctgaggat gccggagcct ttgctggcca
    23701 tccattggga aatctcatca ttgctggctt gtcagaaatg cagggttcaa cctataatgc
    23761 catgcagtta ttgagcaaat ttttccatac aacagggaaa atttatcctt ctagtgacca
    23821 tcctttgacc cttcatgcag tctttcagga tgggacagaa gtggctggag agagtcatat
    23881 tgtagaccat cgaggcataa ttgacaatgt ctatgtgacc aatgccctaa acgatgatac
    23941 gcctctggcc agccgtcgag tagtgcagac catccttgaa agtgacatga ttgtcctagg
    24001 gccaggttcc ctctttacct ctattttgcc caatatcgtg attaaggaaa ttgggcgggc
    24061 tcttttggaa actaaggcag aaattgccta tgtctgcaat atcatgaccc aacgtgggga
    24121 gacggaacac tttacagata gcgaccacgt ggaagtcttg catcgtcacc ttggtcgccc
    24181 ttttatcgac actgtcttgg tgaatattga aaaagtgcct caggaataca tgaattccaa
    24241 ccgttttgat gaatacttgg tgcaagtgga acacgatttt gtaggtcttt gtaagcaagt
    24301 ttcgcgcgtg atttcatcta acttccttcg tctggaaaat ggcggtgcct tccacgatgg
    24361 agatttgatt gtggacgagt tgatgcgcat tatacaggtg aaaaaatgag tttcacagta
    24421 gcagtaaaag aagaaatcct gggccaacac cacctgagcc ggcatgaatt atctgccatt
    24481 atcaaaatgt ctggtagcat cggtctctcg acttcgggct tgactttgtc agttgtgaca
    24541 gaaaatgcca aactggcccg tcacctctat gagtcctttc tccatttcta tgaaatcaaa
    24601 tctgaaattc gtcactacca acggagcaat cttcgcaaga atcgcgtcta taccgttttt
    24661 acagatgaaa aggtgcagga tttgttaagt gatttgcact tggcagactc tttctttggc
    24721 ctggaaacag gtattgatga ggcgatttta tcggacgagg aagcaggtcg tgcctatctc
    24781 tgtggcgctt tcttggcaaa tgggagcatt cgtgaccctg agtcaggcaa gtaccagttg
    24841 gaaatcagtt ctgtttatct ggaccacgcg caaggaattg cctcccttct ccaacagttt
    24901 ttactggatg ccaaggtgct tgagcgcaag aagggggctg tgacctatct ccagcgagca
    24961 gaagacatta tggacttctt gatagtaatc ggagccatgc aggcacgtga tgattttgag
    25021 cgggttaaga ttttgcgaga aacccgtaac gacctcaatc gggctaataa tgccgagaca
    25081 gctaatatcg ctcggacagt ttctgccagc atgaagacca ttaacaatat cagtaaaatc
    25141 aaagatatca tgggcttaga aaatttgcca gtagatttgc aggaagtggc gcaactgagg
    25201 attcagcacc cagactactc tatccagcag ttagcagata gtctcagcac ccctctgacc
    25261 aaaagtggtg tcaatcacag actcagaaaa atcaataaga tagcggatga attataaaac
    25321 cacgaatcct atgtgactcg tggttctttt ttataaacta gtagagtgtt ttggttgtac
    25381 tttttgttca gggtcaatgt agttgatagc gttgttgaca gcagttggag cttctccgag
    25441 gcctgtcgca atcagatcaa tttttccgtc atagtagcag cagtcaccga tagcatagat
    25501 acctgcttgg ctggattcct gtttgctgtt gacgataatc ttgtgacggt tgaggtcgag
    25561 cccccagttt ttaaggttac cgacagaaga tttgaaacca tagttgacaa agaggtggtc
    25621 taggtcaatg gtttcagttt catcagattt gacttttgtg atttcaagtt tatcaagtgt
    25681 ttttccattt ccaaggagtt ggctaggggc gaatggtgtc ttgatggtta cagatgattc
    25741 ttgcaaggct tgaacactgt gttccaaggc acggaaatta tctctgcggt gaacaagggt
    25801 agttggtgcg attttttcaa aagccaaagc ccaatccaca gccgagtctc ccccaccaag
    25861 aatcgtcact ttcttaccag cgtattgctg aatgttagaa acgtggtagt ggatattttc
    25921 atagccctca acactttcaa gttccagcgg acgtggtttg aaggcaccgc cacccatagc
    25981 gatgataact gttttagtca ggtgacttcc tttagaagtt gtgatggcaa attcttcttc
    26041 ttgtttgtca atctcaagaa ccgtttcatt gagatgaata ggggtatcaa atccatttag
    26101 ctgttcaatc aagcggttag tcaactcttc tccagtcagg tttgggaagc ctggtacgtc
    26161 taggatttcc ttttcagggt agagaatagc aggttgtcca cctagctggg gaagagagtc
    26221 gatgatttga accttggctt ggcgtaggtg ggcataaaag gctgcaaaaa gcccgacagg
    26281 accaccaccc acaatggtaa tatcatagag ttgagacata gtttctcctt tgttttttct
    26341 agtcagttta ttttatcata tttttgttca atgtaaaatg gactaggata gggaaaaaaa
    26401 tgccagaaaa tggtataata ggacgaaagt gttttgatag ggaggatatc agggatgaat
    26461 tttcaacaat tatccaatct gcaatattgg accagtttgt ttgcaagtcc atggacgata
    26521 gctatcaatc tgattgatat tttgattgtt gcttatattt tataccattt tacaaaagct
    26581 attgcaggaa ccaagattat gattttggta cgtggagttt tggtgtttat tttagctcaa
    26641 atccttgcaa atatgattgg tttgactacg atttcttggt taatcaatca aattattact
    26701 tatggggtta ttgcggcggt tgttatcttc tctccagaga ttcggactgg tttggaacgt
    26761 ttgggaagag cgacagattt tttttccaat gcccctatta gtgctgagga acagatgatt
    26821 cgtgcctttg ttaagtctgt tgaatacatg agtcctcgta aaatcggggc cttggttgct
    26881 attcagcgtg tacgtacctt gcaggagtat atttcgacag gaattccctt ggatgctaag
    26941 atttctgcag aacttctcat taacattttt attcccaaca ctcccctaca tgatggtgcg
    27001 gtgattatca aagaagaacg tatcgctgtg acgtctgcct atctgccctt gacaaaaaac
    27061 acagggattt ccaaggaatt tgggaccaga caccgggcgg ctatcggttt atcagaagtc
    27121 tcagatgcct tgacttttgt cgtatcagag gaaacgggag gaatctcgat aacctataat
    27181 ggaaggttta agcacaacct aacacttgat gaatttgaaa cagaattacg tgaaatctta
    27241 cttccaaaag aggaagtggg tcttagtttt aaagaacgat tgctaggagg atggaaacat
    27301 gaaaaaaaat agtttatata tcatatcctc actctttttt gcttgtgtct tatttgtcta
    27361 tgctacggcg acgaattttc aaaacagtac cagtgctagg caggtaaaaa cggaaaccta
    27421 tactaataca gtaacaaatg tccctattga catacgctat aatagtgata agtattttat
    27481 tagcggtttt gcttcagaag tatcagtggt cttgactggt gcaaatcgcc tatcgctagc
    27541 tagtgaaatg caagaaagta cacgtaaatt caaggttact gctgacctaa cagatgccgg
    27601 tgttggaacg attgaagttc ctttgagcat tgaagattta cccaatgggc tgaccgctgt
    27661 ggcgactccg caaaaaatta cagtcaagat tggtaagaag gctcagaagg ataaggtaaa
    27721 gattgtacca gagattgacc ctagtcaaat tgatagtcgg gtacaaattg aaaatgtcat
    27781 ggtgtcagat aaagaagtgt cgattacgag tgaccaagag acattggata gaattgataa
    27841 gattatcgct gtcttgccaa ctagcgaacg cataacaggt aattacagtg gttcagtacc
    27901 tttgcaggca atcgaccgca atggtgttgt cttaccggca gttatcactc cgtttgatac
    27961 aataatgaag gtgactacaa aaccagtagc accaagttca agcacatcaa attcaagtac
    28021 aagcagttca tcggagacat cttcgtcaac gaaagcaact agttcaaaaa cgaattaaaa
    28081 atagaaaagg attttataac aatgggtaaa tattttggga ctgatggagt ccgtggagaa
    28141 gctaacctag aactaacacc agaattagcc tttaaactag gacgttttgg aggctatgtt
    28201 cttagtcaac atgaaacgga agcgccgaaa gtctttgtag gacgtgacac acgtatttca
    28261 ggggaaatgc tggaatcggc cttggtggca ggtctccttt cagtagggat tcacgtatac
    28321 aaacttggtg tccttgcaac accagcagta gcttacttgg ttgaaactga aggagcaagt
    28381 gccggtgtca tgatttctgc tagccacaac ccagcccttg ataacggaat caagttcttt
    28441 ggcggtgatg gcttcaaact agatgatgaa aaagaagcag aaattgaagc cttgctagat
    28501 gctgaggaag acactcttcc tcgtccaagt gcagaaggct taggaatttt ggtagattat
    28561 ccagaaggct tgcgtaagta tgaaggatac cttgtttcaa ctggaactcc tcttgatgga
    28621 atgaaggttg ccttggatac agctaatgga gcagcttcta ccagtgcccg tcaaatcttt
    28681 gcagaccttg gtgcccaatt gacggttatc ggggaaacac cagacggtct taacatcaac
    28741 cttaatgttg gttcaacaca tccagaagcc cttcaagaag tggtcaaaga aagtgggtca
    28801 gctattggtt tggcctttga tggagacagt gaccgcttga ttgctgttga tgagaatggt
    28861 gacatcgtcg atggtgacaa gattatgtac atcatcggaa aatacctttc tgaaaaagga
    28921 caattggctc aaaatacaat tgtgacaact gttatgtcta accttggttt ccacaaggcc
    28981 ttgaatcgcg aaggtattaa caaggcagtt actgcagttg gtgaccgcta cgttgttgaa
    29041 gaaatgagaa aatcaggcta caaccttggt ggtgaacagt ctg
//
LOCUS       DAVLZS010000025        28998 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLZS010000025 DAVLZS010000000
VERSION     DAVLZS010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28998
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.025"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..603
                     /locus_tag="VYO88_001175"
     CDS             <1..603
                     /locus_tag="VYO88_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV1719279.1"
                     /translation="YNYSDVKQQKNALGKEIDEKAISNIGLHYDKIKSKESKYYERFE
                     EIYHHKCAYCGVSTAINPALLYEIDHFFNKLQTTFGLDDLSVDIIDNLILSCRNCNQS
                     KKEFAVNDVHSIIHPDSREIKEVFNRGEHFEIKIAPQYCKNEKIQSFYNKMKFHYRFR
                     KLDYLLLNLYFLKEKFPKYEKLYSKLLEFRNSTPSLKKYK"
     gene            646..1866
                     /locus_tag="VYO88_001176"
     CDS             646..1866
                     /locus_tag="VYO88_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1719280.1"
                     /translation="MTNSVSSNRPEKYNIAAFFSGVGGIELGFEQTNEFRVVYANEFD
                     KYARQTYQLNHPDTYLDGRDIHDVQPEDIPAERVDVIMGGFPCQAFSIAGYRKGFDDD
                     RGDLFFELLRMIEGRKPRAIFIENVKNMVGHDHGNTFKVIREALTENNYFIKWKVLNG
                     KDYGNIPQNRERIYIVGFNTKEAYDLFEFPEEIKLTTSLQDVINFGDQLGEVYYYRDG
                     KQNFYDQLKFEVTSQDTIYQWRRQYVRENKNGVVPTLTANMGTGGHNVPLILTDSGEI
                     RKLTPKETFNVQGYPKFFKIPEGVSNGQLYKQAGNSVVVPVIKRIAENVAKALNESQG
                     QSQLNRSGKFAIIYTKMNGQFEGQSYVKDFVDSYDQALEKIKSYDDGLAVLSGEDYLK
                     LVKKRGTLEFYSIN"
     gene            1937..3514
                     /locus_tag="VYO88_001177"
     CDS             1937..3514
                     /locus_tag="VYO88_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719281.1"
                     /translation="MWKHLKSEQKDKYKTLITNFASLSQAFSQKAESDDEGQTENYVA
                     PIVNSKFQETVFQKAFNAVGEDIANTSYDASVVVDENHKYLVGIKSFGINSGDQKIAQ
                     FKKDSQDWTELLGDIKFHADISVDKETADKKNYQRYEELARKIATLRNQRIESSKAQI
                     KGFSSDSVNVEAVYHVLMPTPKGENPKIFVGETSYLPVDIDNLIIEGSTTKNNPTNFR
                     FTDGQHHYKYTAADSQLHMTFNNKDIVVDTWDVHYIEDPFSLFENLHLLTAEKDKTDV
                     LETVSWVITDKHGNVEENSGFNAFNGGSKLAKKDRLPRILKTQEKFKDSLAPEELAFV
                     TFSLEEILLKKWTSKEEKVQMKAIREDLIHFVHNTGNEKLIKEIEQLVYRPVSEVYIP
                     LPDSKSFHDERPDFFGPGFGTFEPGSKKLAMAKEERTFKLRFLPSGDVINAYINQEAG
                     KAIQSTDKQEILGNWILRGVFQLKEREVLTGQRLNELEINGIRLTKFKNGEIGIEFIW
                     IDTENPPSDAIGWVAKK"
     gene            3617..6296
                     /locus_tag="VYO88_001178"
                     /pseudo
     CDS             3617..6296
                     /locus_tag="VYO88_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            6596..7435
                     /locus_tag="VYO88_001179"
     CDS             6596..7435
                     /locus_tag="VYO88_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1719282.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            7453..9291
                     /locus_tag="VYO88_001180"
     CDS             7453..9291
                     /locus_tag="VYO88_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1719283.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVNQGYKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            9304..10719
                     /locus_tag="VYO88_001181"
     CDS             9304..10719
                     /locus_tag="VYO88_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1719284.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTILKRYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            11202..12248
                     /gene="pheS"
                     /locus_tag="VYO88_001182"
     CDS             11202..12248
                     /gene="pheS"
                     /locus_tag="VYO88_001182"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1719285.1"
                     /translation="MSTIEEQLKALREKTLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            12248..12757
                     /locus_tag="VYO88_001183"
     CDS             12248..12757
                     /locus_tag="VYO88_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719286.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            12834..15239
                     /locus_tag="VYO88_001184"
     CDS             12834..15239
                     /locus_tag="VYO88_001184"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1719287.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPCRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQLSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFARLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEATLQPAAPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(15307..16308)
                     /locus_tag="VYO88_001185"
     CDS             complement(15307..16308)
                     /locus_tag="VYO88_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1719288.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            16464..16867
                     /locus_tag="VYO88_001186"
                     /pseudo
     CDS             16464..16867
                     /locus_tag="VYO88_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            16993..17259
                     /locus_tag="VYO88_001187"
     CDS             16993..17259
                     /locus_tag="VYO88_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1719289.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMRELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            17520..19769
                     /gene="metE"
                     /locus_tag="VYO88_001188"
     CDS             17520..19769
                     /gene="metE"
                     /locus_tag="VYO88_001188"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1719290.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGASRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDTDYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            19833..20699
                     /gene="metF"
                     /locus_tag="VYO88_001189"
     CDS             19833..20699
                     /gene="metF"
                     /locus_tag="VYO88_001189"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1719291.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            21384..23597
                     /gene="pnp"
                     /locus_tag="VYO88_001190"
     CDS             21384..23597
                     /gene="pnp"
                     /locus_tag="VYO88_001190"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1719292.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDYKPKKEFTETSKDSE"
     gene            23613..24230
                     /gene="cysE"
                     /locus_tag="VYO88_001191"
     CDS             23613..24230
                     /gene="cysE"
                     /locus_tag="VYO88_001191"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1719293.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRVHGKKDEPVIHEVEEKREYYVNKLEQAKEASHRSSGL"
     gene            24242..25126
                     /locus_tag="VYO88_001192"
     CDS             24242..25126
                     /locus_tag="VYO88_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719294.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            25208..26551
                     /locus_tag="VYO88_001193"
     CDS             25208..26551
                     /locus_tag="VYO88_001193"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1719295.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            26544..26930
                     /locus_tag="VYO88_001194"
     CDS             26544..26930
                     /locus_tag="VYO88_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1719296.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            26934..27818
                     /locus_tag="VYO88_001195"
     CDS             26934..27818
                     /locus_tag="VYO88_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1719297.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            27955..28410
                     /locus_tag="VYO88_001196"
     CDS             27955..28410
                     /locus_tag="VYO88_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719298.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTVYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            28407..28553
                     /locus_tag="VYO88_001197"
     CDS             28407..28553
                     /locus_tag="VYO88_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719299.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            28696..28866
                     /locus_tag="VYO88_001198"
                     /pseudo
     CDS             28696..28866
                     /locus_tag="VYO88_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         9068 a         5077 c         6358 g         8495 t
ORIGIN      
        1 tataactact cagatgtaaa acaacaaaag aatgcattag gaaaagaaat tgatgagaaa
       61 gcaatcagca atatcggact tcattatgat aaaataaaat ctaaagaatc aaaatattat
      121 gaaagatttg aagaaattta ccaccataaa tgtgcctatt gtggagttag cacagctata
      181 aatccagctc ttttatatga aattgatcat tttttcaaca aattacaaac aacatttggt
      241 ttggatgatt tatcagtaga tataattgat aatctaatat tatcttgtag aaattgtaat
      301 caatcaaaaa aagagtttgc ggttaatgat gttcacagta ttattcatcc cgatagtaga
      361 gaaattaaag aagtctttaa taggggagaa cattttgaaa taaaaatcgc accacaatat
      421 tgtaaaaatg aaaaaattca aagtttttat aacaaaatga agttccacta tcgttttaga
      481 aaactagact atcttctttt aaatttatat ttcctcaaag agaaatttcc taaatacgaa
      541 aagttatata gcaaactatt ggaatttcgg aatagcacac ctagtttaaa aaaatataaa
      601 tagtttatag aaatagttgt ttaattttag aaagcaggtt actacatgac aaattctgta
      661 agttcgaacc gaccggagaa gtacaacatt gcagctttct tctcaggtgt tgggggaatt
      721 gagttaggtt ttgaacagac caacgagttc agagtggtgt atgccaatga atttgataag
      781 tatgcgcgtc agacttatca gttaaaccat ccagatacct atttggatgg tcgtgatatt
      841 cacgatgttc agccagagga cattccagct gagcgcgtgg atgtgattat gggaggtttc
      901 ccttgtcagg cctttagtat tgcgggttat cgcaagggtt ttgatgacga tcgtggcgat
      961 cttttcttcg aattgcttcg catgattgaa gggcgtaaac ctcgcgctat tttcattgaa
     1021 aacgtcaaaa acatggtagg tcatgaccac ggcaacacct ttaaggtcat tcgtgaagcc
     1081 ttgaccgaga acaactattt tatcaagtgg aaggttctta acggaaaaga ctatggaaat
     1141 atcccacaaa accgtgagcg gatttatatc gttggtttta ataccaagga agcttatgat
     1201 ttgtttgaat ttccagagga aattaagctg actacgagtc ttcaggatgt gattaacttc
     1261 ggcgaccagc taggcgaggt ttactactat cgtgatggca agcagaattt ctacgaccag
     1321 ttaaaatttg aagtcactag ccaagatacg atttaccagt ggcgccgtca gtatgtccgt
     1381 gaaaataaaa acggtgttgt tccaacccta acagccaata tgggaacagg gggacacaat
     1441 gtccctctga tcttgacaga cagtggcgag attcgtaaac tgacacctaa ggaaaccttt
     1501 aacgttcaag gctatcctaa gttctttaaa attccagaag gggtttccaa tggtcagctc
     1561 tacaaacaag ctggaaatag cgtagttgtt cctgtgatta aacgtatcgc ggaaaatgtt
     1621 gctaaggctt tgaacgaaag ccaaggtcaa tctcaactta accgctcagg aaaattcgct
     1681 attatctaca ccaagatgaa tggacaattt gaagggcaat cctatgtcaa ggactttgta
     1741 gatagttatg atcaagctct tgaaaaaatc aaatcttatg acgatggttt agctgttctg
     1801 tctggtgaag attatttaaa attggttaaa aaacgaggaa ctcttgaatt ttacagtatt
     1861 aattaacgaa tatataagag ggttggtgaa aaattaatct ccttttgata tactgaaaat
     1921 aggaaagaag gtgcttatgt ggaaacatct aaagtctgaa caaaaagaca aatacaaaac
     1981 cttaattacc aacttcgcta gcttgagcca agctttctct caaaaggctg agtccgacga
     2041 tgagggacaa acagagaatt atgttgctcc gattgttaat tctaaatttc aagagactgt
     2101 ttttcagaag gcttttaatg ctgttgggga agatattgcc aatacgtcct atgatgcctc
     2161 tgtcgttgtg gatgaaaatc ataaatacct agtgggtatc aagtcttttg gaatcaattc
     2221 tggagaccaa aaaattgccc agtttaagaa ggactctcaa gattggacgg aattgttggg
     2281 tgatatcaaa ttccatgcag atatctcagt agataaagaa acagcagaca agaaaaacta
     2341 tcaacgctat gaagagttgg cacgaaagat tgcgacctta agaaatcaga gaatcgaatc
     2401 ttctaaggca caaatcaagg gatttagttc ggactcggtc aatgttgaag ctgtttatca
     2461 cgttctgatg ccgacaccga agggagaaaa tcctaagatt tttgtcggtg aaacatctta
     2521 tttgccagtt gatattgata atctgatcat tgaaggatca actaccaaaa acaatccaac
     2581 caattttcga tttacggatg ggcaacacca ctacaaatac acagcggcag atagccagct
     2641 ccacatgact tttaacaata aagacattgt ggtagatact tgggacgtcc attatattga
     2701 agatcctttt tcgctctttg aaaaccttca tttactgaca gctgaaaagg ataaaaccga
     2761 tgtcttagaa acagtgtctt gggttattac agataaacat ggaaatgtgg aagaaaactc
     2821 tggtttcaat gcctttaacg gaggatcaaa actagctaag aaagatcgtc tgccacggat
     2881 tctaaagact caggaaaaat tcaaagacag tctggctcca gaagaactag cctttgtgac
     2941 tttttcttta gaagaaatcc tcttgaaaaa gtggactagc aaggaagaaa aagttcagat
     3001 gaaggctatt cgtgaggact tgattcactt tgtccacaat actggcaatg aaaaactcat
     3061 caaagagatt gaacaactag tttatcgtcc agttagtgaa gtctacattc ctctgccaga
     3121 ctctaagagc ttccatgatg aaagaccgga tttctttggt cctggatttg ggacttttga
     3181 acctggctct aaaaaactag ctatggcaaa agaagaaaga acgtttaaac tacgcttttt
     3241 accttctgga gatgtcatca atgcgtatat aaatcaagaa gctggaaagg cgattcagtc
     3301 aactgataag caagaaattc ttgggaattg gattttacgt ggtgttttcc agttgaaaga
     3361 acgagaagtc ttgacaggtc aacgactcaa tgaactggaa atcaacggta ttcgtttaac
     3421 taaatttaaa aatggggaaa tcggtattga atttatctgg attgataccg aaaatccccc
     3481 aagcgatgcc atcggctggg tagcaaagaa ataaaagttt tcaaaggtat tgtaacaaat
     3541 aagggatttt attttcgtgt acaatttcag ctattcttgt tataatcagc ctataggaat
     3601 caaggaggtg actcttatgg ctgtttttgt gtctttggat ggaattgtgg tagaagtgct
     3661 tgatgtcttt tcttcttttg atggggatag tgagtttttc ttgtgtaaac gtcttaaaga
     3721 caagagtcag tttgttatgg aacgctctca gttcgaggag atgttccaac ttcaaagtag
     3781 tcgcttgacg acgcaagaaa aattacaatt gtttacctct gtgtttgctg gccgttatga
     3841 tgtttatgct aagagtttta tcaatgatca agggaaaatt cagtattttc cttcctatga
     3901 ttatggttgg aagcagttgc tacctgaaaa acggagtttc cagacattga cggattccgt
     3961 tttgaaatct cattttcgtg gggagacagc tatcggtatc tttcctatgc acttagatga
     4021 tagctgtcat tttttggtac tggattttga tgaaggagat tggaaagaag ctggtttaac
     4081 cattcgaaga atagccaggg aacgccagat ggaagcccat ttagagattt ctcgttcggg
     4141 tcacggactc catatttggt tcttctttga ggaagcgatt ccgagtcgag aggctcgctt
     4201 gtttggaaag aaactgatag aactggcaat gcaggaaagt atgcaactgt cctttgattc
     4261 ttttgatcgc atgtttccaa atcaggatgt ccttcctaag gggggatttg gaaatttgat
     4321 tgccttgcct tttcaaggag aagcttacca tcaagggcga acggtctttg tggatgaaca
     4381 gtttcagcct tatgaagacc aatggaggta tctacaagaa attcagaggg tttcaactgc
     4441 taaagtggca ctgttaatcc aagaagagtt aggcaagcaa gaattggaca aggggttgaa
     4501 gatcgtctta tccaatatga tccaacttga aaaatcgtct gtgacaccca agacactgtt
     4561 tttcttgaaa aatatggctt cattttctaa tcccgaattt tatttaaagc aggctatgcg
     4621 acagccaacc tatcaaattc ctgagcgaat gtatttattt ggagaatccg attattattt
     4681 atggctgcca agaggcttgt tatatccatt gcaagataaa tttaagcagg tagttgtgga
     4741 ggataggaga aaggtacaaa ggtctattag agtagcattt aagggagagc ttactttgga
     4801 gcaagaatta gccctgtcag atatgaattc taaagaaaat ggtttacttc atgcgggaca
     4861 ggttttggaa agagcgtttt aggtgctgct cttatctctg aacgtaagac aaaaaccatt
     4921 atcctagttc ataataggca actcttagac caatgactgg atcgtttaaa gtgttttttg
     4981 actttcgaag aggcagaagc tacccgttat acaccatcag gtcgtgaaag ggtaataggc
     5041 tatgtcgggc agtacggtgg ggctaagaaa tgactgagta aactggttga tgttgttatg
     5101 attcaatctc tatttaagtt ggaaaatagt caaagtcttt tggatgagta tgagatgatg
     5161 attgtggatg agtgtcatca tatctctgcc ttgatgtttg aaaaagttgt tgctcagttt
     5221 agagggaagt atctttacgg tttgacggct acgcctgagc gtaagaatgg tcatgagcct
     5281 attgtttttc agagaattgg tgagatactc catactgctg ataagaggga aacggatttt
     5341 aaacggcaat tgcaattaag attcacttct tttggtcatt tggagattga aaagaccaaa
     5401 gcaagtaatt ttatacagct tagtgattgg attgctactg actcagcgag gaatcagttg
     5461 attctcaagg atattctagc ccaagtggca gaaggacgga atatcttggt tttagttaat
     5521 cgaattcaac agatagatgt ctttgaaaag ttattgaaag agaaagaggt tgatgactgt
     5581 tacattatta gcggaaaaac caacgtccga gaaagagaac gagtttactg gagacgttag
     5641 aacagttaga taaagggttt attttgttgt ttactggaaa atacattggc gaaggttttg
     5701 acttacctca gttggacacg cttatcttgg cagcaccctt ttcttggaaa aataatttga
     5761 ttcagtacgc aggtcggatt catagaaact acaaggataa gtctttggtg cgtattttcg
     5821 attatgtgga tattcatgtt ccttatttag aaaagatgtt tcagaaacga caagtagctt
     5881 atcgaaagat ggattatcgt gccattgagg gtgaggagaa acaattcgtt tatgttgata
     5941 gtagatatga gaaggtgttg agagaggact tagcagggga aagacaggaa tgtatgctta
     6001 ttttacctta tgtgcaccag acaaaactga tgaattttct aaaagaattt aggattagtc
     6061 aaattgagat atgtatacca gagacggttg caaataaagc atggctagac cagttgaaga
     6121 gccagaaaat taaagtgtct tttactcaat caaaaatagt aacgcctatt cttttggtga
     6181 ataagactat tgtttggtat ggtgcaatgc cattattagg gaaggtagat gagatgacca
     6241 tattacgttt ggaatcagct agtatagttt ctgaactagt ggcaggttta cgatagagaa
     6301 aatttttaaa aatttctatg tatgattttc atttctttag tgagactgtt gccattatca
     6361 cattcgaatc acacaaaata aaaaaatttc tacaagtact tgacaaatag attgaaatat
     6421 cttaaaatga aaatggttac agagttatta attatttaag cttcatgtca ccattaaaaa
     6481 ttgaaataaa aggatgttat cactaataca agtgagcagg aacctattta atcacatcag
     6541 aagaagtttc ttgatgtttt taagtaggtt ccttttattt taaaagggaa attttatgat
     6601 cataaaacga atactaaacc acaatgccgt aattgcgcaa agtaaaaaag atatcgatat
     6661 tcttcttttt ggaaggggaa tagcttttgg aagaaaaact ggagataaag taaatccaat
     6721 tgatattgag aaaagttttt ttctcaaaaa tagagataat atgacccgtt ttacagagat
     6781 gtttattaac gttcctttgg agttggtgta catcaccgaa aaaataatta acctaggtaa
     6841 aataacatta ggtaataatt ttgatgagat tatctatata aatctaacgg atcatatttc
     6901 ttcgagtata gaacgttata aagaaggagt tattatttcg aatcccctac gctgggaaat
     6961 ctcgaaatat tataaagaag aatttgagct tgggaaaagg gctttacaaa taataaaaaa
     7021 agagttaggt attgaacttc caattgacga agctgcattc atagcgctac attttgttaa
     7081 tgctaattta gaaaataatt ttcaagagtc gtataaaatc actgaaataa ttatgggaat
     7141 tgagaaaatc attcaagatt tctattgtac tgagtttaac caagattcta ttgattatta
     7201 tagattcata actcatataa aattatttgc ccatcgcttg gttgaaaata caacttattg
     7261 tgacgatgat gatgaagact tgttagcatt aatgaaaaat aaatatccta gagaatatga
     7321 atgtggtgaa caggtggcaa tgtttataca aacggagtac aattatttgc tgacttctag
     7381 tgaattagtt tatttgatgg ctcatattcg tcgcttaaca aaaaatttag attaatagaa
     7441 taggagaata ccatgagtta taaagatacg gtacaaaaaa tcctcgatgt aattggaggc
     7501 gaaaaaaatg tcaatagagt tacccattgt gtaacacgtt taagattaga attaaaagat
     7561 gaaaatttag tcaatgatga tgatgtgaag aagataccag gtgtaatagg tattatgaaa
     7621 aagaatggac aatatcaaat tatacttggt aatgatgtag ctaattatta taaagaattc
     7681 gttaaacttg gcaattttga atccgattca gttaatcaag ggtacaaagg gaatatttta
     7741 gaaagaatca ttgagtatat cgctggttcc atgactccaa tcattccagc aatgttaggg
     7801 ggaggtatgt tgaaagtctt ggtaatcatt ttaccaatgc ttggtatatt gcaatcagat
     7861 tctcagacta ttgctttttt gacatttttt ggggatgctc catattattt cttaccgctg
     7921 ttattagctt attctgcatc acaaaaatta aaagtaacat ctacattagc tatgtctgta
     7981 gcaggtgtac ttctccatcc aaattttgtt caaatggtgc aatcagggaa tcctcttagt
     8041 ttatttggtg tacctgtgac accagctagt tatggttcgt cagtcgttcc aattcttatt
     8101 atggtttggt tgatgaaata tattgaaaaa atgattgcta aattaacacc agctgttact
     8161 aagagttttt tgcaacctac gctagtatta ttagtatcaa gctgtattgc cttagttgta
     8221 gtcggaccta ttggagtaat tgttggtgaa ggattatcaa atctagttgg gcaaatgtat
     8281 ggtgtagctg gatggcttac attagctatt cttggtgcta ttatgccatt tattgttatg
     8341 actggaatgc attgggcttt tgcacctatt tttttggcgg catctattgc tactccagac
     8401 gtattaattc ttccagcaat gttagggtca aacttagctc aaggggctgc ttcgatggct
     8461 gttgcattaa agagtaaaaa taataataca aaacaaattg cttttgcagc aggtttctca
     8521 gccttacttg caggaattac cgaacctgca ttatatggtg tgactttaaa atataaaaaa
     8581 ccgctttatg cagctatgat tggtggtgga ttagcgggat tatttgcagg tcttactagt
     8641 gttaaagcgt atctatttgc tgtcccatct ttgatagcgt tgcctcaatt tatttattct
     8701 gatgtaccat caaatattgt aaatgcttta attgtggcgg tcatttcggt tgttattacc
     8761 tttgtattag cttatatatt tggaatcgat gaagaagaga gttctagtaa tttagaagtt
     8821 aaagctggag tttcaaataa aaaaatgata ttttctccta tatcaggaga aatcattccg
     8881 ttaagcgatg tccaggataa aacattttca gataaactaa ttggagacgg agtagcgatt
     8941 atcccaagtg aaggtaaggt ttatgcacca tttgatggga aaattacaaa tatttttccg
     9001 actaagcacg caattggatt gaagagtgat gagggtgttg agttactaat tcatattgga
     9061 ttagatactg ttgagctaaa aggtcaaggt tttattagtc atgtagaaga aggagacaga
     9121 gttttcaaaa atcagttgat ttttgaaatg gacttgaatt taatcaagac taaaggctac
     9181 gaaacagtta caccagtaat tgtaacgaat accaatgatt ttctagatgt attagtatta
     9241 cctaataatc agacaatcga gcattctaag gaattactgg taatattata atggaggaaa
     9301 gttatgacca tttttccaga tgattttctt tggggtggag ctgttgcagc taatcaagta
     9361 gagggagcat ataatgaaga tggtaagggc ttatcagttc aggatgtgtt acccaaaggt
     9421 ggattaggag aagcaacaga aaatcctaca gaagataact taaaattgat aggtattgat
     9481 ttttatcata aatataagga agatatatcc ttgttttctg aaatgggctt taatgttttt
     9541 cgtacttcta ttgcatggag tagaattttt ccaaaaggag atgaggaaga acctaacgaa
     9601 gctggtttga aatattatga tgaattattt gatgaactac atgctcacgg gatagaacca
     9661 cttgtaactc tttcacacta tgagactcca ttatatttag caagaaaata tcatggatgg
     9721 attgatagga gaatgattca tttttatgaa aaatttgctc gaacaatttt aaaaaggtat
     9781 aaagataaag ttaaatattg gcttacattt aacgaagtaa actctgtttt ggaattaccg
     9841 tttactagtg gaggaataga tatacctaag gagaatcttt cgaaacaaga attatatcaa
     9901 gctatacatc atgaattagt cgcctcgagt ttggttacaa aaattgctcg tgagattaat
     9961 tcagagttta aggtggggtg tatggtatta gctatgccag cttatccaat gactccaaat
    10021 ccaaaagatg tatgggcgac tcatgagtat gagaatctaa attatctatt ttcagatgtg
    10081 catgttagag gttattatcc gaattatgca aaaagatatt ttaaggaaca tgacattaac
    10141 atagagtttg cagctgaaga tgcagagtta ttaaaaaatt ataccgtaga ttttttatcc
    10201 tttagctatt acatgagtgt gactcaatct gctcttccaa cacagtataa ttcaggagaa
    10261 gggaatatta ttggtggctt agtaaatcct tatttagagt cttctgagtg gggatggcaa
    10321 attgatccaa ttggactacg tataatttta aatagatatt atgaccgtta tcaaatccca
    10381 ttatttatag tggaaaacgg attaggtgct aaagatcaac taataaaaga tgaatttaat
    10441 aacttaacag tccaagatga ttatagaatt cagtatatga aagaacattt attgcaagta
    10501 gctgaagctc tacaagatgg tgtggaaatt atgggctata cgtcttgggg atgtattgac
    10561 tgcgtttcta tgtccactgc acagctttct aagaggtacg gtctcattta tgttgatcga
    10621 aatgatgatg gaaatggcac attcaatcga tataagaaaa tgtcctttac ttggtataaa
    10681 ggagtgattg aatcaaatgg agaatcctta ttcaaatagt ttgtttattg atgattagat
    10741 attatcacgg ttaaggcaac atctcattga atatggaata aagaagtttg gaagacatta
    10801 aattctaaac ttctttattt tataggggag tgtcaattaa tttaattttg ttacaaaaat
    10861 tataaatagt taatttagat aaattgttta tataaattta gataagaata agctaacaag
    10921 cagaagtaag ataggtcttg caagaatggt aaaaatctga taaactaagt agtaattgaa
    10981 taggaatctg aaagactagt agcccaaggg aagtatatca gggaggagag ccgtgactgc
    11041 aagctctcta tatgaaagct gggtgaattc acttgcgcat ggatttagaa atgaaggtct
    11101 gacttgtcag atgaaaacgg atggtaccgc gtgtcaacgc tccgagtgga gtttttggca
    11161 tgtggttttc tttttatcta cgagagactg atggaggaaa tatgtcaact attgaagaac
    11221 aattaaaagc gcttcgcgaa aaaacgctga ctagcttgaa gcagattact gctggaaatg
    11281 aaaaagagat gcaagatttg cgtgtctctg tccttggtaa aaagggttcg ctcactgaaa
    11341 tcctcaaagg gatgaaagat gtttctgctg agatgcgtcc aatcatcggg aaacacgtca
    11401 atgaagctcg tgatgtcttg actgctgctt ttgaagaaac agctaagctc ttggaagaaa
    11461 agaaagtcgc ggctcaactg gctagcgaga gtatcgatgt gacgcttcca ggtcgtccag
    11521 ttgcgactgg tcaccgtcac gttttgacac aaaccagtga agaaatcgaa gatatcttca
    11581 tcggtatggg ttatcaagtc gtggatggtt ttgaagtgga gcaagactac tataactttg
    11641 aacgtatgaa ccttccaaaa gaccacccag ctcgtgatat gcaggatact ttctatatca
    11701 ctgaagaaat cttgctccgt acccacacgt ctccagttca ggcgcgtgct atggatgccc
    11761 atgatttttc taaaggtcct ttgaagatga tctcgccagg gcgtgtcttc cgtcgcgata
    11821 cggacgatgc gacccacagt caccaattcc accaaatcga aggcttggta gttgggaaaa
    11881 atatctctat ggctgatctt caaggaacgc ttcagttgat tgtccaaaaa atgtttggtg
    11941 aagagcgtca aattcgtttg cgtccatctt acttcccatt cacagagcca tctgttgagg
    12001 tggatgtttc ttgcttcaag tgtggtggag aaggctgtaa tgtatgtaag aaaacaggtt
    12061 ggatcgaaat tatgggggcc ggtatggttc acccacgtgt ccttgaaatg agtggtatcg
    12121 atgcgactgt atactctggc tttgcctttg gtcttggaca agagcgtgta gctatgctcc
    12181 gttatggaat caacgatatc cgtggattct accaaggaga tgtccgcttc tcagaacagt
    12241 ttaaataatg attagaaaag tagaaatggc agatgttgag gtgttggcta aaattgccaa
    12301 acaagccttt cgtgaaacct ttgcgtatga taatacggaa gagcagttac aggaatactt
    12361 tgaagaggct tatagtctga aaactttgtc aactgagttg ggaaatcctg actctgaaac
    12421 ctatttcatt atgcatgagg aggagatagc tggttttctc aaagtcaact ggggaagtgc
    12481 tcaaactgag agagaattag aggacgcttt tgaaattcaa cgcctctatg tgctacaaaa
    12541 attccaagga tttggactag gtaagcaact gtttgaattc gcacttgaac ttgctacaaa
    12601 aaatagtttt tcttgggctt ggttaggtgt ttgggagcat aatacaaaag ctcaagcctt
    12661 ttataatcga tatggttttg aaaaatttag ccaacatcat tttatggttg gtcaaaaagt
    12721 agatacggat tggttactga gaaagaaatt aaggtaagaa gaggattctt ctattgaaat
    12781 gataggaaag gaaaagaact agagtgacaa ctgtcattct ggagaactaa attatgcttg
    12841 tatcttataa atggttaaaa gaattggtgg acattgatgt gccatcacaa gagttggctg
    12901 aaaaaatgtc aactacagga atcgaggtag agggtgtcga atcaccagct gctggtctct
    12961 caaaaattgt cgtcggtgag gtcttgtctt gcgaagatgt gccagagact cacctccatg
    13021 tttgtcaggt taacgttggc gaagaagaag agcgtcagat cgtttgtggt gccccaaatg
    13081 tgcgtgctgg gatcaaggtc atggtggctc ttccaggagc tcgtatcgct gataactaca
    13141 aaatcaaaaa aggaaaaatc cgtggtttgg agtcacttgg aatgatctgt tcacttggtg
    13201 aattgggaat ttctgactca gttgtgccta aggaattcgc agatggcatc caaatcttgc
    13261 cagaaaatgc cgtgccaggt gaggaagtct tttcttacct agacttggat gatgaaatca
    13321 tcgaactttc catcacacca aaccgtgcag atgccctttc tatgtgtgga gtggctcacg
    13381 aagtggcagc catctatgac aaggcagtca actttaaaga atttactcta acagaaacta
    13441 atgaatctgc ggcagatgcc ctttctgtca gcattgggac agacaaggcg ccttactatg
    13501 cagctcgtat cttggacaat gtgactatcg caccaagtcc acaatggttg caaaaccttc
    13561 tcatgaacga aggcatccgt cccatcaata acgttgtaga cgtgacaaac tacatcctgc
    13621 tctactttgg tcaacctatg catgcttttg acttggacac atttgaaggg actgacatcc
    13681 gtgtgcgtga agcgcgtgct ggtgaaaagt tggtgacctt ggacggtgaa gaacgtgact
    13741 tggacgtgaa tgacctagtc atcactgttg cagacaagcc agtagccctt gcaggtgtca
    13801 tgggtggtca agcaacagaa atctctgaaa aatctagtcg tgttgtcctt gaagctgctg
    13861 ttttcaatgg caaatctatc cgtaagacaa gtggtcgcct gaaccttcgt tctgagtcat
    13921 cttctcgctt tgaaaaagga attaatgtgg caacagttaa tgaagccctt gatgcggcag
    13981 ctagcctgat tgcggaactt gcaggtgcga cggtgcgtaa gggcatcgtt tcagcgggtg
    14041 agcttgatac ttcagatgta gaagtttctt caacccttgc tgatgttaac cgcgtcctcg
    14101 gaactgagct gtcttatgct gatgtagaag acgtcttccg tcgtcttggc tttggtcttt
    14161 ctggaaatgc agacagcttt acagtcagag tcccatgtcg tcgttgggat atcacaatcg
    14221 aagctgacct ctttgaagaa atcgctcgta tctatggtta tgaccgcttg ccaactagtc
    14281 taccaaaaga cgatggtaca gcaggtgaat tgacagccac acaaaaactc cgccgtcaag
    14341 ttcgtactat tgctgaagga gcaggtttga cagaaatcat cacctatgct ctaacaactc
    14401 ctgaaaaagc agttgagttt acggctcaac taagtaacct tacggaactc atgtggccaa
    14461 tgactgtgga tcgttcagtc ctccgtcaaa atatgatttc aggtatcctt gataccgttg
    14521 cctacaacgt ggctcgtaag aataaaaact tggcccttta cgagattgga aaagtctttg
    14581 aacaaacagg taatccaaaa gaagaacttc caaatgaaat caacagtttt gcctttgcct
    14641 tgacaggctt ggttgctgaa aaagatttcc aaacagcagc agttccagtt gattttttct
    14701 atgctaaggg aatccttgaa gccctatttg ctcgtttggg actccaagta acctatacag
    14761 caacatctga aatcgctagc cttcatccag gtcgtacagc agtcatttca ctcggtgacc
    14821 aagttcttgg tttccttggc caagtgcatc cagtcactgc taaggcttat gatattccag
    14881 aaacgtatgt agctgagctt aacctttcag ctatcgaagc tacgcttcag ccagcggctc
    14941 catttgtaga aatcaccaaa ttcccggcag tcagccgtga cgttgccctt ctcctcaagg
    15001 cagaagtgac tcatcaagaa gttgtagatg ctatccaagc tgccggcgtg aaacgtttga
    15061 cagatatcaa actttttgac gtcttctcag gtgagaaatt gggacttggt atgaagtcaa
    15121 tggcttatag cttgaccttc caaaatccag aagatagctt aacggacgaa gaagtcgcac
    15181 gctatatgga aaaaatccaa gcatcgctcg aagaaaaagt caatgcagaa gtgcgttaaa
    15241 cgatagtatg atacaaattc cccctctagt ttatgaacac tagaggggtg attttatata
    15301 aaataattaa aatgtgattt ctgtaaaaat acatctatga tcagagtttt gaaaacttac
    15361 aatgtctaaa tctttaacat agtagtggtt tttaggcaat aaaatatgat ctattgttgc
    15421 attaaaaagt tttggacttt ggctattcca agttcctctt tcaaaaggtg gcagtacatt
    15481 taatgcgtcc ctatgagagc ttatttttgc aagtgctcca tgacgcatag ttgcattaaa
    15541 atcacctgca ataatagcct ttggatattt tgaagccaat tgattatgaa tgatgtttaa
    15601 gtcttgcttc cagatttcca ttaaacctgg cagaggagga gcagtatgca aggcaatgat
    15661 atctggtata ttttgttttc tcgaatgtaa tacaattgtc ccgaaccgtg ttgtatgaaa
    15721 agttttagct tctgtataga aaccataact tttcttgaca atcacagtca caggagctat
    15781 tccactattg gtaggtggag aagtgaaaat atcatagttg gccatagaaa gtccaacttg
    15841 atgaaacaat agtttgattc tctggttttc ttgctcacct ctgatattgg tagctagttc
    15901 agggaatata gccatatcgg catcaaaatg gctaaaaatt cgctcaatat gttgtgcttc
    15961 tatttgatta gcgacgttcc aagttactaa ttttaaggtt ttagtcttat ttgatgcaga
    16021 agaaagggtt ttatctgttc cgaataatag taatatgagc gatagtaaga gcaaaatgcc
    16081 agagtaaaac cgtatttgtt tatttttctt gtaaaaagat aggaaaaaaa atacgaaact
    16141 taaaatagca gccatagttg cagtagctaa ggggaaggca taaatctgtg ccaagatagg
    16201 ttgggtagat agccaaatgt taagattaga agatgggaaa aaagaataag ttatgatagg
    16261 gatagaaaag agaatgaccg aaagggcaga gagaaatgtt ttaatcattg tgtgagtacc
    16321 tcaatttgca atggttgctc ggagctaatg tgactttgtg actttacttg attgatattc
    16381 tttttcttgt cttcctcata gattaagtac aacccaagta aaaaaagtcc aatttaagat
    16441 tgaaatgatt aaaaggcaca gaaatgcaag acaattatac tacaaaaggc aaacatttga
    16501 caatcgatag ccgtcgctta atcgaacgat ggaaaaaaga aggaaaatca aatagagaaa
    16561 ttgcctctct acttggaaaa gctcctcaaa ctatccacac tgaaatcaag cgtgggacag
    16621 tccgacaatg tcttggaaaa gggcgcttca aagagattta ttctgccgac tacgctcaac
    16681 agtcttaaga aactaaagga aaagattctc cactatacat aaccaaaaat tttcgcctga
    16741 aatgatggtg atggctaaag gggttaacgt gggaatttca accatttact attggattca
    16801 tcgtggaaaa ttggggttaa gcaagcagga actgctttat cctagaaaag gaaaatcgct
    16861 taagaaatag gctagcacca actttaaacc cactggtcaa tctatcgaat cataatttgc
    16921 tcattttttt aaaaatacat agacgtaaaa aaaagagggt taagtgatga agaatagtgc
    16981 tattgggagt aattggaagg atgtccatct gagctcttta gcaaggagga aatccttgaa
    17041 agtgatatgc gagtggctat catgagagag ttgattgagg ctaggtatga acaaggaatc
    17101 agtcagaaaa agctggaaga agtcagtgga ataagccagc ctgtcatagc taggatggag
    17161 acaggaaaga ctagtcctca gttggataca gtcttaaaag tcctagccag tttaggaaag
    17221 acactagcaa tcgtcccact tgaacaggga aaaagttgac tagaatcagt tatagtcttt
    17281 tctaataaca agccatagtc acttataaga attactaata acatgtttta gtattctaat
    17341 tggaatatag ctgtaaagta agaattacaa aggatttgag gcatttttct caggtctttt
    17401 tcttttgttt aaaacagaga tatagtttca aactatatca aagcctaatt ttttacaatt
    17461 atacagatga tttcttttct gttaagatag tttcaacaac aaattttgga ggacacatca
    17521 tgtcaactac aatcatcggt ttccctcgtt tgggcgaatt ccgtgaatta aaatttacaa
    17581 ctgaaaaata ctttagaaaa gaaatctcag aagaagaact tttagcagca gcaaaagact
    17641 tgcgtgctaa acactggaac attgtcaaag aaaaaggcat cactgaaatt ccatcaaatg
    17701 acttttctca ctatgataac ttcctagatg cggctttcct tttcaacgtg gtgcctgcat
    17761 ccgttcaaaa cttggacttg tctgaccttg agcgctactt cgctttggga cgtggttacc
    17821 agggagaaaa aggggacgtt cgcgcccttc caatgaagaa atggttcaac actaactacc
    17881 actacatcgt tcctaaattt gaaaaagaca ctcaagtaaa attggctggt cacaagattt
    17941 tcgatgagtt ccaagaagcc aaagaacttg gattgaacac tcgtcctgtt cttgtaggtc
    18001 ccttcacttt ccttcaattg tcagactttg aagaaggcgt gaaagcagac gacttcgtag
    18061 atagcttagt ggctgcttac caagaagttt ttgctaaatt ggctgaactt ggtgcgagtc
    18121 gcatccaatt ggatgaagcg gctcttgtaa aagacttgac agctgaagaa aaagctctct
    18181 tcttgaacct ttacaacaaa ctcttggctg acaaaaaagg tcttgaagtc ttgcttcaaa
    18241 cttatttcgg tgatgttcgt gacgtatacg ctgaccttgt aaacttacca gtagatgcta
    18301 tcggtcttga ctttgttgaa ggtaagaaaa ctcttgaact cgttaaaggt ggcttcccag
    18361 ctgacaagac tctctatgta ggtattgtca atggtaaaaa catctggcgc aacaactacg
    18421 aaaagagctt ggctgttctt gagcaaatcc cagctgaaaa catcgttttg acaagctctt
    18481 gctcacttct tcatgtgcca tttacaactg ctaatgaaga atttgaacca gcactcttga
    18541 accactttgc ctttgcagtt gaaaaattgg atgaaatccg tgacttggat gctatccgca
    18601 atggtcaagg ttcagaagct cttgcagcca acaaagaact ctttgcgact gagcgtgttg
    18661 gtgaaaatgc tgaacttcgt gcgcgtatcg ctggcttgac agacacagac tacactcgtt
    18721 tgccagcctt tgcagaacgt gaagctatcc aagaagaagc tttcaaactt ccagctcttc
    18781 caacaacaac gattggttca ttccctcaaa caaaagaagt tcgtgccaaa cgtttggctt
    18841 accgtaaagg tgaattgtct caaaaagagt acgatgcttt ccttgctgaa acgattgacg
    18901 aatggatcaa gtggcaagaa gatattgact ttgatgtcct tgttcacggt gaatttgagc
    18961 gtaatgacat ggttgagtac ttcggtcaaa acttgtcagg atacctcttc tctaaaaatg
    19021 gatgggtaca atcatacggt atgcgtgggg taaaaccacc aatcatctgg ggtgatgtca
    19081 ctcgtcttaa ccctatcact gttaaatggt ctagctatgc acaaagtcgt acaaacaaac
    19141 ctgttaaagg tatgttgact ggacctgtta ccatccttaa ctggtcattc ccacgtgaag
    19201 acatctctat caaggattca actctccaaa tcgcccttgc tatcaaggat gaagtacttg
    19261 accttgaagc tgctggtgtg aaaatcatcc aaatcgacga ggctgctctt cgtgaaaaat
    19321 tgccactccg ccgtagcgac tggtacgaag actaccttga ctgggctatt cctgccttcc
    19381 gcttggtaca ctcaacagta gcgccagaca cacaaatcca cactcacatg tgttactcag
    19441 aatttacaga tatcatccca gctatcgata acatggatgc agacgttatt tcctttgaag
    19501 ctagccgttc aaaccttgaa atcttggacg aactcaaagc gaaaaacttc caaacagaag
    19561 tgggacctgg ggtttacgat atccactcac ctcgtgtacc aaatgaaggc gaaatcgaca
    19621 acacaatcga agccatcctt gctaaagtgc caagcaagaa agtttggatc aaccctgact
    19681 gtggtttgaa aacacgtggt atcccagaaa caaaagaaag cttgatccgc cttgttgaag
    19741 cagctaaagc tgcgcgtgag aaattgtaag attggatttc tctccataca gtggttgttc
    19801 aaaaagaaat caactagaaa aggttattac atatgtcacg ccaaacaccg tcactctcat
    19861 ttgaagtgtt ccctccaaac ccagccgtgg gtaatggtaa cattatttca gccttgcagg
    19921 atatgcagga gttggctccc cattttatca gtgtaactgc cagcaataat aaatttaata
    19981 tcaaggaaac gacggttcgt ttggctgact ttatccaaaa tgatttggcg attccgacca
    20041 ttgcccactt gccagctatt tatctaacta aggacaaggt tgctgaaact attgctgact
    20101 tggacaaagt tggggtgcag aaaatcttgg ctcttcgtgg ggatattatt ccagacgtgg
    20161 aaccacaaaa ggatttccgc tatgcaaccg acttgattga gtttatcaag gaacaaaccc
    20221 ctcactttga tattattgga gcttgctatc cagaagggca tccagattcg ccaaatcaga
    20281 tttcagatat tcaaaatctt aagaagaaag tggatgcagg ctgttcgagc ctcgtaactc
    20341 agctcttctt tgacaatgag cgcttctatg attttcagga caagtgcatc ttggctggga
    20401 ttgatgttcc cattcatgca ggaattatgc caattctgaa tcgaaatcag gctctccgac
    20461 tcttgaagac ttgtgagaat atccatcttc cacgcaaatt taaagccatc ttagacaagt
    20521 atgagcatga ccctgaatcg ctcagagcag caggacttgc ctatgcagtg gaccaaatcg
    20581 tggacttggt aactcaggat gttgccggtg tgcatctcta tacgatgaat aatgctgata
    20641 cagcaaaata catccatcaa gcaacccatg ccttgtttaa tcaccagtct ctaggataat
    20701 aaaagcaaac cattcttctc aggtgagggg aatggttcct ttttaatggt aaagacctca
    20761 ctttttaaga aaaatatgat aaaataaatt ctgtacgtac ttgatacaaa gatgaaggta
    20821 ttaaataata caatgcattt aaactgtaag atttaacgac acgagtgagt caaatcgatg
    20881 ttatttgacg agagagttag taaagcattt agctaatcgc ccgatagcga ttagcgtgaa
    20941 agctttagat actttagtat taaacctttc taatgatgta tcttgaaaac tgaacttgcc
    21001 tacaactctg tggaaaaaga taaatctccc taggagcagt cgctccgtcg ttcgatttcc
    21061 tattttcctt tgagttgctt gacggcttgg tatcttgagt aattgaattt tggtctcatt
    21121 tcttaggaaa aaagataagc ttcctagcac tcgtcgagtg cgacgtcacc ttcctatttt
    21181 tctacagaaa tgttcggcaa gccgaaccgt ccaaaatatc ttgtgtaatt gaacacggcc
    21241 gaaaagctgt gtaaaaaaga taaactgtct tgtcttcatc gaagacttcg tcagtttcct
    21301 atttttactt tgcttttgac gtccttggta tcttgatctt tgtaggcaag gcgtataatt
    21361 tcatcaatcc aaaggggatt aaaatggcaa aacaagtgtt tcaaacgact tttgcgggtc
    21421 gtgagttaat tgtagagact ggtcaggttg ctaagcaagc aaatggctct gttgtcgtac
    21481 gttacggtga gtcaactgtc ttgactgctg ccgttatgtc taagaaaatg gcaactgggg
    21541 attttttccc actccaagtc aactacgaag aaaaaatgta tgcggctggg aagtttcctg
    21601 gtggctttat gaaacgtgaa ggacgtcctt caacagatgc gaccttgaca gcgcgtttga
    21661 ttgaccgtcc gattcgtcct atgtttgcgg aaggtttccg taatgaagtc caagtcatca
    21721 atacagtgct ttcttatgat gaaaatgcat ctgcaccaat ggctgctatg tttggttcat
    21781 ctttggcact gtctatttca gatattccat ttgacggacc aattgctggg gtacaagtgg
    21841 gatatgtaga tggccaaatc atcatcaacc caagtcaaga acaagcagag caatctcttc
    21901 ttgaattgac agtagctgga accaagcacg ctatcaacat ggtagagtct ggtgccaaag
    21961 aattgtcaga agaaatcatg ttggaagcgc ttcttaaagg gcacgaagct gtcaaagaat
    22021 tgattgcctt ccaagaagaa atcgttgctg ctgtcggtaa agaaaaagca gaagtggaat
    22081 tgcttcacgt ggatgctgaa ttgcaagctg aaatcattgc agcctacaac agtgacctcc
    22141 aaaaggcagt tcaagtagaa gagaaattgg cccgtgaagc tgcaactcaa gcagtgaaag
    22201 accaagtgac tgccgtttac gaagaaaaat atgcgaacca cgaagaattt gaccgtatta
    22261 tgcgtgatgt ggctgaaatc ttggaacaaa tggaacacgc agaagtgcga cgtttaatta
    22321 cagaagacaa ggtgcgtcct gatggtcgta aggtcgatga aatccgtcct ttggatgcgg
    22381 ttgttgactt ccttcctcgt gtacatggtt caggtctctt tactcgtggg caaactcaag
    22441 ctctttcagt cttgaccttg gctccgatgg gagaaactca aatcattgat ggtttggatc
    22501 cagagtacaa gaaacgcttt atgcaccact ataacttccc tcaatattct gtaggggaaa
    22561 caggtcgtta cggtgcgcca ggtcgtcgtg aaatcggtca cggtgccctt ggtgagcgtg
    22621 ctcttgctca agtcttgcca agcttggaag aattcccata cgctatccgt ctagtagcag
    22681 aagttttgga atcaaacggt tcttcatctc aagcttctat ctgtgcggga actcttgccc
    22741 ttatggctgg tggtgtgcca atcaaggcgc cagtagctgg tattgctatg ggacttatct
    22801 cagatggaaa taactacaca gtattgacag atatccaagg tttggaagat cactttggag
    22861 atatggactt caaggttgca ggtactcgtg atgggattac agcccttcaa atggatatca
    22921 agattcaagg gattactgca gaaatcttga cggaggctct tgctcaagcc aagaaagcgc
    22981 gttttgaaat ccttgatgtc attgaagcaa ccattccaga agttcgtcca gaattggctc
    23041 caactgctcc gaaaattgat acgatcaaga ttgatgtgga caagattaag attgtcatcg
    23101 gtaagggtgg agaaaccatc gacaagatta tcgctgaaac aggtgttaag attgatatag
    23161 acgaagaagg aaatgtgtct atctactcta gtgaccaaga tgctattaac cgtgccaaag
    23221 aaattattgc tggtttggtt cgtgaagcca aagtggatga agtttaccgt gctaaagtcg
    23281 ttcgtatcga gaaatttggt gcctttgtta acctctttga taagacagat gcccttgttc
    23341 atatctctga gatggcttgg actcgtacca atcgtgtaga ggatttggta gaaatcgggg
    23401 atgaagttga tgttaaggtt atcaaaattg atgaaaaagg ccgtatcgat gcctctatga
    23461 aggctcttct acctcgtccg ccaaaacctg agcatgatga aaaaggtgaa aagtctgagc
    23521 gccctcaccg cccacgtcat caaaaggatt acaaacctaa gaaagaattt acagaaacat
    23581 caaaagattc agaataagaa aaggagaaat gtatggggtg gtggcgcgaa accattgata
    23641 ttgtaaaaga aaatgatcca gcggcccgca ccactttgga ggttttgctg acttatccag
    23701 gtgtcaaggc cttggcggcc caccgtctct cgcattttct ctggaagcac ggcttcaaac
    23761 tattagctcg tatgtacagt cagttttggc gcttttggac tcagattgag attcatccag
    23821 gagcccagat tgattcaggt gtttttattg accatggttc tggtctggtg attggagaga
    23881 cagcgattgt tgaaaaaggc gttcttctct atcacggagt gactctcggg ggaacaggga
    23941 aagactgtgg caaacgccat ccgactgtac gaaagggagc tttaatatcc gctcatgctc
    24001 aagtcattgg acccgttgaa atcggtgaaa atgccaaagt cggtgcagca gcagttgtcg
    24061 tggcagacgt gcctagtgat gtgacggttg tcggtattcc ggccaagatt gtccgtgtac
    24121 atggtaaaaa ggatgagcct gtcattcacg aagtcgaaga aaaacgagag tactacgtca
    24181 ataaactcga gcaggctaaa gaagccagtc acagatcgtc tggtttgtag aggataccta
    24241 tatgattcaa gcaagaaaca agttaagcca agaagagcta tctgaggcga aaaaagtaat
    24301 taactgttgc caaaactatg acggtaccta tcgcgatccc tatctctcta acatgcttaa
    24361 ttttgaccca aacatgcccg cctttttcct ttattatgaa aaaggcgaac ttgttggttt
    24421 attaactgtc tatgcagatg accaagatgt agaagtgacg atactggttc atccaggtca
    24481 tcgccgtcag gggattgcgc gtgcattgtt tactagtttt gagagagaaa cagcttcttt
    24541 ccccattcgg tcagtcactt ttcagacaga acgtattttt ttagagaatc atcctgactt
    24601 tgccagtaac tggggactaa tagaggatga agagacagaa acttggttag gtaaggatag
    24661 aagaccttat ccgttagcaa atgtttccca tcttgaagtt ttgttagcag atagttcgta
    24721 tcaggatcaa attagtcaat taaaatttca ggcattttca gaggaacatg aatcgagaga
    24781 agttgtggat agatatgtcg ctgaagctct gaaggatcca gaaagtcgct tatatatttt
    24841 gttaaaagac ggtcaggtta ttgggacttg cacggtagat ttatcgacta atacgaatta
    24901 cttctacggt ttagcaatat cagaacctga acgtggaaaa ggctatggaa gctacttagc
    24961 aaaatccctc gtcaaccaac taattgagca aaatgacaag gaatttcaga ttgcagtgga
    25021 agatagcaat gtaggtgcca aacgtttgta tgaaaaaatt ggctttgtca aacagactca
    25081 ggtggtttat ctgaatgaga aaggagcaag ggattccgaa gtgtagagat attcggactg
    25141 aaatttactt gaacttttag tgatgaaact aattgttctt ggatttcagc tttcctgatt
    25201 atgatttatg attaaaatct atgacaccat gtctcgtgat ttgcgagaat ttgtcccgat
    25261 tgaggacggc aagatcaaga tgtatgtttg tgggccaacg gtgtacaact atatccacgt
    25321 aggaaacgcc cgttcgacgg tagcttttga tacgattcgt cgctattttg agtaccgtgg
    25381 gtataaggtt gcctatattt ccaattttac agatgtagat gataagatta tcaaccgtgc
    25441 cagggaagaa ggtatcacgc ctcaggaggt tgcggataag tacatcgctg cctttcgtga
    25501 ggatgtgacg gcattgggcg tgaaacctgc gactcgccat ccgcgtgtag tggagtttat
    25561 ggcagacatc atccgttttg tggaagactt gatcgagaaa ggctttgcct atgagagtca
    25621 aggggatgtc tatttccgtg tagaaaaatc ccacaactat gctaaattgg ctaataaaac
    25681 cttggaagat ttggagctag gtgcttcagg tcgtaccgat gaagaaacgg ctcgtaagga
    25741 aaatcctgta gactttgctc tatggaaatc ttccaaacca ggtgagattt cttgggatag
    25801 tccttgggga cctggacgtc cgggttggca tattgagtgt tcagtcatgt cgacagagat
    25861 tttaggtgat accattgata tccacggtgg tggagctgac ctagagtttc cacaccacac
    25921 caatgaaatt gcccagtctg aagctaaaac aggcaaggct tttgctaact actggatgca
    25981 caatggcttt gtcaatatcg acaatgtcaa aatgtctaag tccttgggta acttcattac
    26041 ggtacacgat gcccttaaaa ctcttgatgg gcaagtactt cgtttcttct ttgcgaccca
    26101 gcactaccgt aagcctatca acttcacgga aaaggcagtt cgcgatgccg agaccaatct
    26161 caagtatctc aagaatactt acgaacaacc atttacagga aatgtggatg cccaagagtt
    26221 acaaaacttt aaagataagt ttgtagcagc tatggatgaa gattttaatg ctgccaacgg
    26281 tatcacagtt gtctttgaaa tggccaaatg gatcaactca gggaactatg atgcaagtgt
    26341 caagcaagct cttgcagata tgttagaaat ttttggaatt gtctttgttg aggaagtttt
    26401 ggatgcagag attgaagact tgattcaaaa acgccaagag gcgcgtgcca atcgtgactt
    26461 tgcgacagca gaccaaatcc gtgaccaatt ggttactcaa ggaattaagc tccttgatac
    26521 caaggatgga gtgaggtgga cacgtgattg atgtcaatct cattaacggg attgcgctag
    26581 cctttgaggg ggatgcggtg tattctatgt atattcgccg tcacctcatc ctcaaaggta
    26641 tgaccaaacc caataaactc catcaagaag cgaccaagta cgtgtcagcc aaggctcagg
    26701 ctcgcctgat tgctctcatg ttggaggagc aggtcctaac ggaaaaagaa gaagaaatct
    26761 acaaacgtgg ccgcaatacc aatagccaca caaaggctaa aaatgcagat gtcgtgactt
    26821 atcgtatgtc cacgggattt gaagcggtta tgggctatct ccatatgact gagaatctgg
    26881 aacgtcttga gagtttggtt tcatggtgca tccaaaaagt ggagggctag aacatgaggg
    26941 caaaagaact acaagactgg tttcctgagg ctcggatttc agaccaacca gtagagaaag
    27001 agggctatct cacgctccct ttagcttctc agcagtggat tttgctggag gaagctgggc
    27061 tcagcgagcg tgaaaagcag ttggttgccc ttttgaccca gcaggagcag gctcgttcgc
    27121 taaacccttg gtattcctat ctggttgagg gcaagggaca ggcaccgcaa gtttttaaaa
    27181 agattcagtt ggtttattgc catctttctt attttcagca ggaaaatctg gcttcttggc
    27241 tagatatgat gcggactctt tttccgaatt gtcagacagt gctacaggtc ggagctcagg
    27301 attatgtttt cgtgcttcaa caagacaaat acacttctgt aagagatatt ttaagtgata
    27361 cgattgaagc ggttgagtat gactttggac ttcgtctttc tatcatgttg ggtcaggttt
    27421 ggtctcagac gggacatcaa gccctatcag acttaatcaa agctgagcgg gatttgttca
    27481 agacatggtg gcgtcagggt caccaaggtg ttcatacttt ttctcagctc tatctttgga
    27541 gtatgggaga aagactcgtg gacttgaagc caatcaagga atgtctacac cagatgattt
    27601 tggatcaaga tcagattcag gaaatcattc tctctctttg ggaaaatagt gctgttctca
    27661 ctaaaacagc ccagcaactc tatctgcacc gcaattctct ccaatacaag attgataaat
    27721 gggaagagtt gacagggctt cagttgaaag agttgaccga cctgaccttg tgttatcaat
    27781 tgattttagg ttctttgtca actatagttg gtttgtaaag aagttaatat ttggagaaga
    27841 ggattgccat cttctccatt tttatgtgca gagttatagt ggcttgatgc tgggaaagta
    27901 cactgtgact gctaaaacat tcctagaagc tgctttgatt tccctaatct atttatgcaa
    27961 attttatgtt attttactat aacagttgtt gctaagccaa ataatagtgg ggaagttcat
    28021 ttagacgtaa gcattgaaga taatcaggga ggtagtgggt ataatttcag ttctgtttca
    28081 agtagctcac aaacagctaa atatgaagga actgtttata ataacaattc atcattatat
    28141 ataacgattg ataaaacgtc tgatgcaaca gctcttttga aattaaagtt gaataatgtt
    28201 gataatcaac ctgctactga agttcctagt tcaggaatta ctgtaaaatt aaatgctaaa
    28261 gataatgctg gaaactggac aagtgcttcg aataaaaaag aagtaacagt aaaaattgtt
    28321 tctgctaaac cgacatatcc agacaaaatc ttagtgaaaa atcctgataa tataaaagat
    28381 acagaaaaaa tgccattatt gaaaaattga aagaggcaaa taaaaatcat ccagcaggag
    28441 ctccaacctt tgctaaaggt gaaggagagc atgcaaatga tattgtagca acttattcag
    28501 atggtacaac ttattatgta ccgttaaatg atgtgacaaa atatgcgagg tagtggctgt
    28561 accactcact tattcacctc cccgtgattt gtagtagtga taggctttct cactattatt
    28621 ataaaacaaa ataaagatca caacactttt tcattctgtg ttgtgccttg agtgaaacga
    28681 aaggaatgaa ttataaatat gaaaagtata gtcactagca tagatgagcg cttgcgtact
    28741 cgcctacgag tgattatctg gaagcaatgg aagaagaaat cgagacgatt atggggattg
    28801 cttaagttag gggttcctaa atggatagca gataaggtat ctggctgggg cgaccactat
    28861 caattatatt aaaatgaaat aagaatagga cgaatcgatc agggaagtca aatcgatttc
    28921 taacaatatt ttagaagtag aggtatatta ttctagtttc aatctactat agtatctcag
    28981 aagtcggtac ttaaacgt
//
LOCUS       DAVLZS010000026        25757 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLZS010000026 DAVLZS010000000
VERSION     DAVLZS010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.026"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            121..918
                     /locus_tag="VYO88_001199"
     CDS             121..918
                     /locus_tag="VYO88_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1719300.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1066..2325
                     /locus_tag="VYO88_001200"
                     /pseudo
     CDS             1066..2325
                     /locus_tag="VYO88_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2421..3695
                     /locus_tag="VYO88_001201"
     CDS             2421..3695
                     /locus_tag="VYO88_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1719301.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKEHDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRQEKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYIVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3705..4583
                     /gene="truB"
                     /locus_tag="VYO88_001202"
     CDS             3705..4583
                     /gene="truB"
                     /locus_tag="VYO88_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1719302.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4824..5126
                     /locus_tag="VYO88_001203"
     CDS             4824..5126
                     /locus_tag="VYO88_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1719303.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5234..5872
                     /gene="udk"
                     /locus_tag="VYO88_001204"
     CDS             5234..5872
                     /gene="udk"
                     /locus_tag="VYO88_001204"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1719304.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            6000..7340
                     /locus_tag="VYO88_001205"
     CDS             6000..7340
                     /locus_tag="VYO88_001205"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1719305.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQVTIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQWDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     RQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAETKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKNVKTKEI"
     gene            7318..7530
                     /locus_tag="VYO88_001206"
     CDS             7318..7530
                     /locus_tag="VYO88_001206"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1719306.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7527..8402
                     /locus_tag="VYO88_001207"
     CDS             7527..8402
                     /locus_tag="VYO88_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1719307.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8395..9210
                     /locus_tag="VYO88_001208"
     CDS             8395..9210
                     /locus_tag="VYO88_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1719308.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVFNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9203..9634
                     /locus_tag="VYO88_001209"
     CDS             9203..9634
                     /locus_tag="VYO88_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1719309.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9641..11308
                     /gene="recN"
                     /locus_tag="VYO88_001210"
     CDS             9641..11308
                     /gene="recN"
                     /locus_tag="VYO88_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1719310.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11310..12038
                     /locus_tag="VYO88_001211"
     CDS             11310..12038
                     /locus_tag="VYO88_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1719311.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGVVAED"
     gene            12117..13940
                     /gene="lepA"
                     /locus_tag="VYO88_001212"
     CDS             12117..13940
                     /gene="lepA"
                     /locus_tag="VYO88_001212"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1719312.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14144..14224)
                     /locus_tag="VYO88_001213"
                     /pseudo
     CDS             complement(14144..14224)
                     /locus_tag="VYO88_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14398..14874
                     /locus_tag="VYO88_001214"
     CDS             14398..14874
                     /locus_tag="VYO88_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1719313.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIITNSSSSQTNILAQLMNFFTGNGHLEDLSKISEPEKLYAYIDEAIA"
     gene            14912..15202
                     /locus_tag="VYO88_001215"
     CDS             14912..15202
                     /locus_tag="VYO88_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1719314.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAK"
     gene            15222..16024
                     /locus_tag="VYO88_001216"
                     /pseudo
     CDS             15222..16024
                     /locus_tag="VYO88_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            16073..16537
                     /locus_tag="VYO88_001217"
     CDS             16073..16537
                     /locus_tag="VYO88_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV1719315.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            16694..17119
                     /gene="lacA"
                     /locus_tag="VYO88_001218"
     CDS             16694..17119
                     /gene="lacA"
                     /locus_tag="VYO88_001218"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1719316.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            17150..17665
                     /gene="lacB"
                     /locus_tag="VYO88_001219"
     CDS             17150..17665
                     /gene="lacB"
                     /locus_tag="VYO88_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1719317.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            17676..18605
                     /locus_tag="VYO88_001220"
     CDS             17676..18605
                     /locus_tag="VYO88_001220"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1719318.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            18607..19587
                     /gene="lacD"
                     /locus_tag="VYO88_001221"
     CDS             18607..19587
                     /gene="lacD"
                     /locus_tag="VYO88_001221"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1719319.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            19821..20657
                     /locus_tag="VYO88_001222"
     CDS             19821..20657
                     /locus_tag="VYO88_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1719320.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            20693..21010
                     /locus_tag="VYO88_001223"
     CDS             20693..21010
                     /locus_tag="VYO88_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1719321.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKGAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            21010..22701
                     /locus_tag="VYO88_001224"
     CDS             21010..22701
                     /locus_tag="VYO88_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1719322.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            22910..24316
                     /gene="lacG"
                     /locus_tag="VYO88_001225"
     CDS             22910..24316
                     /gene="lacG"
                     /locus_tag="VYO88_001225"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1719323.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILLVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            24453..24617
                     /locus_tag="VYO88_001226"
     CDS             24453..24617
                     /locus_tag="VYO88_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1719324.1"
                     /translation="MESLGKWYVSTGKEWICHSDDELEEFKNLFLNFINPEEWDTISF
                     DSDFMPFQQS"
     gene            complement(24816..25577)
                     /locus_tag="VYO88_001227"
     CDS             complement(24816..25577)
                     /locus_tag="VYO88_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1719325.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
BASE COUNT         7878 a         4633 c         5703 g         7543 t
ORIGIN      
        1 aagtagaggt gtactattct agtttcaatc tactataaac ttttatgaaa tacagaaaac
       61 gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa aaaagattta ggagtttatt
      121 atggtttctt cagaatttat ttcaaagatt gaatttgctt gcaataagaa agaaagtctt
      181 tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt tcgcaggtgc atttttaacc
      241 ttcagtactg ctgcaggtgc agttggggct gacttgatta ataaaattgc accaggtagt
      301 ggacgcttcc tctttccatt cgtttttgct tggggcttgg cctacattgt ttttttgaat
      361 gccgagttgg tcacttcaaa catgatgttc ttgactgctg gtagtttctt aaaaaaaatc
      421 tcttggagaa aaacagctga gattttacta tactgtacct tgttcaacct tatcggagcc
      481 ttgatagcag ggtggggctt tgctcattcg gcagcctatg cgaatctgac acacgatagt
      541 ttcatctcag gtgttgttga gatgaagtta ggccgctcaa atgaattggt tttgcttgag
      601 gcgattttgg caaatatttt cgtaaatatt gcgattctgt catttatttt ggtcaaagat
      661 ggtggtgcca aactttggct tgtgttgtca gctatttaca tgtttgtatt cttaacaaac
      721 gagcacattg cggcgaactt tgcttctttc gcgattgtga aattcagtgt tgctgcggat
      781 tcaattgcca acttcggtgt tggaaatatg cttcgccact ggggtgtgac tttcatcgga
      841 aactttatcg gaggaggcct cttgatgggt cttccatatg ccttcctcaa taaaaacgaa
      901 gatacttatg tagattaaga aaatgagcac gattgagtcg tgcttttttc attttcaaaa
      961 taagataata gctatttctt atatcaaaat atagaaaact gatatttgta aactataact
     1021 caaggtgcta caatatcctt aataaaataa tatggaggtc accttatgac tcgtgatttt
     1081 aaatttgaaa ctctacaact acatgctgtt caagttgtgg ctccagctac taagtctcgt
     1141 gcagtgccga tttatcaaac aacatttttt gtttttgatg acacgtagga aggtgccgat
     1201 atgtttgcct tgaggaaacc agggaacatt tatactcgta tcaccaatcc tacaacagct
     1261 gcccttgaag gtggtgttga agcgctagca acagcatcag gtatgactgc agtgacttat
     1321 actattttgg cgattgccca tgctggtgac catgtagtgg ctgcttcgac tatttacggt
     1381 ggaaccttca atcttttgaa agaacccctt cctcgttatg gtatcacaac aacctttgtc
     1441 gatattgata atttggagga agtagaagca gctatcaaag acaataccaa gcttgtcttg
     1501 attgaaacct tgggtaaccc cttgattaat attccagacc tggaaaaact ggcagagatt
     1561 gctcataaac atcaaatccc acttgtgtca gacaatactt ttgcaacacc ttatttgatt
     1621 aacgtcttct ctcatggcgt tgacattgcc attcactctg cgactaagtt tatcggtggg
     1681 catggtacaa ctattggagg aataattgtc gatagtggtc gttttgactg gacggcttca
     1741 gggaaattcc ctcaatttgt tgacgagggt ccaagctgcc acaatttgag ttatactcgt
     1801 gatgtgggtg cagcagcctt tattatagct attcgagttc aattgcttcg tgatacaggt
     1861 gcagccttgt caccattcaa tgctttcctc ttgctacaaa gacttgaaac cctttcactt
     1921 cgtgtggaac gccatgtaca aaatgctgag acaattgttg attttcttgt caaccatcct
     1981 aaggtagaaa aggtaaatta tccaaaactt gcagatagtc cttatcatgc cttggctgag
     2041 aaatacttac caaaaggtgt gggctcaatc tttaccttcc atgtcaaagg tggggaggcc
     2101 gaagcccgca aggtcattga taatttggaa atcttctcag accttgctaa cgtggcagat
     2161 gccaagtctc ttgttgttca tccagcaaca accactcacg gtcaattgtc agacaaagac
     2221 ctagaagccg caggtgttac accaaaccaa atccgcttgt cgatcggact tgaaaatgta
     2281 gaggatttga ttgaagattt gcgcttggcc ttggaaaaaa tttaaagtaa aagaagataa
     2341 acagtgggtt ttgactcact gtttttgatt ttccctcagg catgatataa tggttaaaga
     2401 agtctagaaa gaggaacgat atgaacgaaa tcaaatgtcc caactgtggg gaagtcttta
     2461 cagtaaatga aagccagtat gctgaacttt tatcccaagt gagaacggca gagtttgata
     2521 aggaactaca tgatcggatg aggcaggaac tggccttggc tgagcaaaag gctatgaatg
     2581 agcaacagac taaactggct cagaaggatc aagaaattgc gcaattgcag agtcagatcc
     2641 aaaactttga tacagaaaaa gaattggcca agaaagaagt tgaacagaca agccatcagg
     2701 ctctcttggc taaggacaag gaagtacagg ctttggagaa ccaattggcc actttgcgtt
     2761 tggagcatga aaatcaactg caaaagaccc tttctgacct agaaaaagaa catgatcagg
     2821 tcaaaaatca gctcctcttg caagaaaagg aaaatgagtt gtctttggct tctgttaagc
     2881 aaaactatga agcccagctt aaagcagcta gtgaacaagt cgagttttat aagaatttta
     2941 aggctcaaca atctacaaaa gcgattgggg aaagcctaga acagtatgca gagagtgagt
     3001 ttaacaaggt tcgtagtttc gcctttccaa atgcttactt tgagaaggat aacaaggtct
     3061 cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg tgatgaaaat ggagttgaaa
     3121 tcatttctat catgtttgag atgaaaaacg aagcggacgg aacagagaag aagcacaaaa
     3181 atgcagattt ttacaaggaa ttggacaagg accgtcagga gaagaactgt gagtatgccg
     3241 ttttggtgac catgcttgag gccgataatg actactttaa cacagggatt gttgacgtca
     3301 gccacgagta tgaaaaaatg tatattgttc gtcctcaatt ctttatccaa ttgattggtc
     3361 tcttacgtaa tgcggcgcta aattccctaa aatacaagca ggagttggcc ttggttcgcg
     3421 agcaaaatat tgacattacg cattttgagg aagacttgga tgcctttaag ctagcttttg
     3481 ctaagaacta taattcagct tcgactaact ttggaaaagc tattgatgaa atcgacaagg
     3541 ccatcaaacg catggaagag gttaagaaat tcctgaccac atctgaaaac caactccgtt
     3601 tagctaacaa caaattggaa gatgtctctg ttaaaaaatt gacccggaaa aatccaacaa
     3661 tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc aaaaatgaac ggtattatca
     3721 acttaaaaaa agaagcagga atgacctcgc atgatgcggt ttttaaactg cgtaagattt
     3781 tgggaaccaa gaaaattggt catggtggaa ccttggatcc ggatgtggtg ggtgttttgc
     3841 cgattgcggt tggcaaggcg acacgcatgg tcgagtttat gcaggacgag ggtaagatct
     3901 atgaggggga aattactctg ggttattcca cgacgactga ggatgctagt ggggaagtga
     3961 tcgcagaaac ccctgttttg tctcccttgg atgaaaagct tgttgatgaa gcgattgcta
     4021 gcttgactgg gcctattacc cagattcccc ctatgtattc ggcagttaag gttaatggtc
     4081 gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga gcgtccagaa cgtcaggtga
     4141 ccatttatca atttgagcga acaagtccga tttcttatga tggccaactt gcccgattca
     4201 cttttcgtgt aaaatgcagt aaagggactt acatccgtac tttgtcagtt gatttgggtg
     4261 aaaagcttgg ttatgcggct catatgtccc atttgactcg tactagtgct gctggcttac
     4321 aattagaaga cgctcttacc ttggaggaaa ttgctgaaaa agtagaggct gggcaattag
     4381 attttctcca tcctttagag attgggacag gtgaccttgt caaagttttc ctaactccag
     4441 aagaggctac agaagttcgc tttggtcgtt ttattgagct agaccaaacg gacaaagaac
     4501 tggctgcctt tgaagatgat aaattgttag ccattctaga aaaacggggc aatctctata
     4561 agccaaggaa ggtttttagc tagatcgttt aggaataaaa atcgggtgat agataacaat
     4621 tgcttgataa aaccccatac taatagtaga atggttttgg gaattataat attccaattg
     4681 ttgcgagttg tagatactca aataatctat atagaaattt agaggtgtga aatgaagcaa
     4741 cttaaaattc tttcagataa atatttagag tccattacag gttctggtgg gaacttaggc
     4801 ccaggatttg gtgtgataat tccatgatgc gaaatgagtt tcgagaaagg gtggagcaac
     4861 ttcttcaaca aaaagaaata aatgaaaata gtgagttgag tcacctgttt cgtcttgcta
     4921 tacaaaattt agacagaaat gaaaaatacc aatcggtcat ggccaatttg agtcaagggt
     4981 tgtcacttta cctcatgacg catcattacc aggcacctaa gtctgtcatt gattttggtt
     5041 tatggattgc caaagctcct agccaggaaa gagggagact ggctttcttg cagatgcttg
     5101 ctcaaaccct acagggcttt cgttaaaact gtcgaacatc agagggaaga ctctggtgtt
     5161 ttttgctgat gagactataa attttgtaaa aaatgtgata gaatagacga cggataaaat
     5221 aacggaggat agcatgcaaa atagaccaat cattattgga gtgacaggtg gttctggtgg
     5281 tggtaaaacc agtgtttcaa gagccatttt atcgcatttt cctgatgaaa agatttccat
     5341 gattgagcat gattcatact acaaggatca gtctcatttg acctttgaag agcgtgtcaa
     5401 aaccaactat gaccatcctt ttgcctttga tacagacttg atgatcgagc agattaagga
     5461 attgttggca gggcgtccgg tggacatccc gacctacgac tatacagagc atacacggag
     5521 tagcaagacc tatcgtcagg agcctcaaga tgtctttatc gttgagggca ttttggtctt
     5581 ggaggacaag cgtctgcgcg atttgatgga tatcaagatt tttgtggata cggatgacga
     5641 tgtgcgtatt attcgtcgta tcaagcgtga tatggaggag cgtggtcgta gccttgatag
     5701 cgttattaac cagtacttag gtgtggtcaa accaatgtac caccagttta tcgagtcaac
     5761 taagcgttat gctgatatcg tcattcctga aggggttagc aataccgtgg ctatcgacct
     5821 gttgacgacc aagattgcaa agattttgga agaagctcga aacagcaaat aatcacatgt
     5881 ggaggcctta cctccttttt ctatttttcc ctcataatgg tacataaatg gagattttta
     5941 ggcatatttt tggtataata atacccatga aagagcaagt aaatgaatag taggtggaga
     6001 tggaaaagta tttatcggta acaactttga ccaagtatct gaaaatgaaa ttcgataaag
     6061 acccatactt ggaacgggtc tatttaactg gtcaagtttc caactttcgt aaacgaccta
     6121 ctcaccaata tttctcccta aaggatgacc atgcagttat tcaagtgacc atctggtctg
     6181 ggatttatca gaaattaggg tttgacctgg aagaaggaat gaagatcaat gtgattgggc
     6241 gtgtacaggt ctatgaacca agtggtagct actccatcat cattgaaaaa gctgagcctg
     6301 atggggttgg ggcgcttgcg attcagtttg aacaacttaa gaaaaaattg acagaagaag
     6361 gcctgtttca agaacgcttc aagcaagctc taccccaatt ttctaagaga attggggtag
     6421 taaccagccg tagtggagcc gttattcgag atattatcac gaccgtcagc aggcgattcc
     6481 caggtgttga catccttctt tatccgacca aggttcaagg tgaaggggct gcggaggaaa
     6541 ttgctagaaa tattgcgcgt gctaatcaat gggacgattt ggatttgctc attattggtc
     6601 gtggaggtgg ttctattgag gatctctggg cctttaacga agaaattgtg gtacgagcta
     6661 tttttgaatc tcgtttgcca gttatctcta gtgtggggca tgagacggat gtgaccttgg
     6721 cagattttgt ggcagatcga cgcgctgcaa cgccaacagc ggcggctgaa ctggcaacac
     6781 ctgtgaccaa gttggatgta ttagctcatt tgcaaaatca ggaaaaacgg atggcaacgg
     6841 cagtccgaaa tgttctatct aagaaacaag aggctttgaa aaaatgcagt cagtctgtta
     6901 tctttagaca acctgagcgc ttgtatgacg gttatttgca acgcttggac caactgcaac
     6961 tgcgtttgaa acaaagtttg cgaactcgga tttctgataa cagacaatta gttcaagcaa
     7021 gaactcatca attagtacaa ttatcacctg ttaccaaaat ccaacgctat caagaccgtt
     7081 taggacagtt ggacaagctc ttaggtagcc aaatggcgtt agtttatgac gccaaggttg
     7141 ctgagaccaa gcgactttcg gaagctttgc tcatgttgga tactagccga atcgtggcgc
     7201 gtggttatgc tattgtaaaa aaagaagagt ccgttgtaga ttcggttgag agtttgaaga
     7261 aaaaagacca agtaacgctt ttgatgcgag atggtcaagt agaattagag gttaaaaatg
     7321 tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg aaaccattgt ccaaagtttg
     7381 gaaaatggtg aaattgctct ggaagatgcg attactgcct ttcaaaaggg catggtcttg
     7441 tcaaaagagc tccaagctac gctggacaag gctgaaaaga ccttggtcaa ggtcatgcaa
     7501 gaagacggaa cagaaagtga ttttgaatga aaaagcaaga aaaattagct cttgttgagt
     7561 cggctttgga agatttttat ggagaccagc agtttgcctc tagtttacgg gagtctgttc
     7621 tctattctat tcatgctggt ggcaagcgta ttcggccttt tctcttgtta gaagttctgg
     7681 aagccttgca ggttgccatc aaacctgctc acgcgcaggt agctactgcc ttggagatga
     7741 ttcatacagg gagcttgatt cacgatgacc ttcctgctat ggatgatgac gattatcgaa
     7801 gagggcggtt aaccaatcac aagaaattcg gtgaagctat ggccattttg gctggagatg
     7861 ccttattctt agacccatat gccttgattg cgcaggcaga tttgccaagt cagatcaagg
     7921 tggacttgat tgccaactta tcccttgctt caggtagtct gggtatggtg gcagggcaag
     7981 ttttggatat ggagggcgaa caccagcact tgtctctgga agaacttcag actattcatg
     8041 ccaataagac tgggaagtta ctagcctatc ccttccaagc ggcagctatt atagctgaat
     8101 tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga attgattgga cttgcttttc
     8161 aagtcagaga tgatgtactg gatgtgacag ctagttttga ggaaatcggc aagacacctc
     8221 aaaaggatct gcaggcagaa aaatcaacct atcctgcctt gttgggcttg gaagagtcca
     8281 ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa attagaagaa attgcccagc
     8341 agcttccctt tgaaacagaa tcgattgtaa gtgtagtaga aagtttgaga atcaatggct
     8401 aaggaaagag tggatgtact agcttataaa caggggttgt ttgaaacgag agagcaggcc
     8461 aagcgaggtg tgatggctgg cctagtcgta gcagtcttta atggagaacg gtttgacaag
     8521 ccaggagaga aaattccaga tgacaccgaa ttaaaactca agggggagaa actcaagtat
     8581 gtcagccgtg gtggtttgaa actggaaaag gccttgcagg tctttgattt gtcggtggat
     8641 ggcgcgacta cgattgatat cggggcctct actggaggtt ttaccgatgt catgctacag
     8701 aatagtgcca agttggtctt tgcagtcgat gttggtacca atcagttggc ttggaaatta
     8761 cgccaagacc cacgagttgt cagcatggag cagttcaatt ttcgctatgc tgaaaagact
     8821 gatttcgagc aggagccgag ctttgccagt attgatgtga gtttcatttc ccttagtctg
     8881 attttgccag ccttgcaccg tgtcttggct gatcaaggtc aggtggtagc acttgtcaaa
     8941 cctcagtttg aggcaggacg tgagcagatt gggaaaaatg gaattattcg agatgctaag
     9001 attcatcaga atgtccttga atctgtaaca gctatggcag tagaggcagg tttttcagtc
     9061 cttggcttgg acttttctcc catccaaggt ggacatggaa atattgaatt tttagcgtat
     9121 ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg agattaaaga agcagtagag
     9181 agggcgcata gtcaatttaa aaatgaataa aaaagaaaga cttgaaaaaa ttagaagatt
     9241 ggtgacagat tatcaaatcg gcacgcaaga agaaattgta gaacatttga aagaagcagg
     9301 tatcactgcc actcaggcga cggtatcccg agatatcaaa gagttaggta ttgtcaaaat
     9361 tcctttgaga gacaacacct atgtctacga attaccaaaa tcaatcgtaa aaagtctgca
     9421 actggctgaa gacaatatcg aatcggctga attgatggat aagatgatca atctccaagt
     9481 tattccagga aatacggctt ttgtaaaagc tcagttaatc gatacttttg cagacaagat
     9541 ttttagttgt ttgactgatg atagctcgat tttagtcatt gccagaagtg gaagtctagc
     9601 agaggaaatc tttgaacaag taaaaaattg gtaggtctat atgttacttg aaatttcgat
     9661 aaaaaacttt gccattattg aggctatttc cctcaatttt gaaaagggga tgactgtcct
     9721 gactggtgaa acgggtgcag ggaagtcgat tatcattgat gccatgaata tgatgttggg
     9781 agctcgtgcg acgacagatg ttattcgtca tggtgcacca aaggcagaga ttgaggggct
     9841 tttctcagtt gagaatagtc gccttttaca ggaaattttt gatgagcaag gtttagaatt
     9901 aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat ggtcgtagta tcagccgtgt
     9961 aaatggtcag atggttaatc tgtctgtttt gcgagctatt gggcaacatc ttgtagatat
    10021 tcatggtcag catgaccatg aggagttaat gcgtccccaa ctgcatatcc agatgttgga
    10081 tgaatttggt gatgccgctt tttgggactt gaaagaaacc tatcaaacga gttttgatgc
    10141 ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa aaccaacagg aacacaaggc
    10201 acgtatcgaa atgttggaat ttcaaatggc agagattgag gcagcaaact tgcaggctgg
    10261 agaagacttg gctctcaatc aagagcgaga taaactcctc aaccacaaaa atattgcgga
    10321 tacactgacc aatgcctaca gtatgttgga caatgaagat ttttcaagtc tggccaatgt
    10381 tcgttcagct atgaatgaca tggaaagtgt cgaagagtat gatcctgaat accgtgaaat
    10441 ttcaagctct ctgtctgaga cctactatgt tttagaagac attagcaaac gtttggaagc
    10501 tatcattgag gaccttgatt ttgatggcaa tcgcctgatg caggttgaga atcgtttgga
    10561 cctccttcat actattactc gtaagtatgg tgggactgtt gatgatgttt tgctttattt
    10621 tgccaagatt acggaagaat acaatctctt gacaggcaat aatctttcgt ctgaggacat
    10681 ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat ttggcaggtc aacttgcttc
    10741 tgctcgtcat aatttggctc agcaactcga agctgagatt aaacaagaac tgcaagatct
    10801 ttatatggaa aaagcccagt ttcaggttcg ttttagtaag ggaaaattca gtcgtgaggg
    10861 aaatgaaatg gttgagtttt atatttcaac caaccctgga gaagacttta aacccttggt
    10921 taaggttgct tctggagggg aattatctcg tctcatgtta gccattaagt ctgccttttc
    10981 acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg gatacgggag tttcaggtcg
    11041 tgttgctcaa gctattgctc agaaaattca taaaattggt cagcatggtc aggttttggc
    11101 tatctcccat ttgccacaag taattgcgat tgcagattat caattcttta ttgagaagat
    11161 tagtaatgac cattcaacgg tttcgactgt tcgtctcttg acggtcgaag agcgagtgga
    11221 ggaagttgcc aagatgttgg caggtgatga tgtgacagaa gcagccctga cgcaagccag
    11281 agaattgttg agaaacaggg agaaataaga tgacagatta ttatgtaatt ggagatgttc
    11341 acggaaaagc tgggatgctg gaagaccttc tcaaaacctg ggatggtcag ccccagttgc
    11401 tctttctagg tgatttgatt gacagaggtg aggatagtca ccgtgttctt gaaatggtca
    11461 aggacttggt ggacaatcaa ggggctatct gtttgtccgg aaaccacgag tatatgtttt
    11521 tgacttggct agatgaccca gaagaaagtt atgaccatta tcgtcgcaat ggtggagata
    11581 caaccattaa ctctatccta ggtcgtccct tggatgcacc agttgatgga gtagaagatg
    11641 ccaagcgggt tgccgctgaa gcgtcagact tggtcgaatt cattcgtcaa atgccatttg
    11701 tagtagagac agacaagtat atatttgttc acgcaggtat tgatttgact ttggacgact
    11761 ggcatgaaac aacagattat aaaaaagtat ggcttagaaa accattccac ggagctgaaa
    11821 atcatactgg aaaaaccatt gtcttcggtc atacaccggt ctatggtttg ttacagcaag
    11881 aacgcggtac atctgagctt tggactacag aagatggcaa gattggaatg gatggaggag
    11941 ctgtttatgg tggtgtcctt cacgggattg tctttacaga ccaaggaatg acagaacacc
    12001 actttatcga aaatgacggc gttgtcgctg aagattagta ctcctagcag ggtatggtct
    12061 tgtcaaaata tcaaaaacaa tttataataa atagataccc tgaaaggaag agaatcatga
    12121 acttagaaga attgaaaaaa cgacagggga agatccgtaa cttctctatt atcgcccata
    12181 ttgaccacgg gaaatcaact ctagcagacc gcattttgga aaaaacagag acggtttcaa
    12241 gtcgtgaaat gcaggcccag cttttggata gcatggatct agagcgggaa cgtggaatta
    12301 ctattaagtt gaatgccatc gagttgaatt acactgcaaa agatggggaa acttatattt
    12361 tccacttgat tgacacacca gggcacgttg actttaccta tgaagtttca cgttcgctag
    12421 ctgcctgtga gggtgctatt ttggtggtcg atgcggctca aggaattgag gctcaaactc
    12481 ttgccaacgt ttatctggct ttggataatg atttggaaat catgcctatc attaataaaa
    12541 ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga gattgaagat gtgattggtt
    12601 tggatgccag tgaagcagtt ttggcttctg ccaaggctgg tattgggatt gaagaaatcc
    12661 tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga tgtgacggcg ccacttaagg
    12721 ccttgatttt cgactctgtt tacgatgctt accgtggggt tatcctccaa gtgcgtgtca
    12781 tggacggagt ggtcaaacct ggtgataaga ttcagctcat gagcaatagt aagacctttg
    12841 atgtggccga agtcggtatt tttacaccaa aagcggttgg tcgtgatttc cttgcgactg
    12901 gtgatgttgg ttacattgcg gcgtctatca agacggttca ggatactcgt gtgggtgata
    12961 ccgttacctt ggcaaccaat cctgcggcag aaccattaca tggttataag cagatgaatc
    13021 ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa gtacaatgac ctgcgtgaag
    13081 cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt tgaaccagaa acatctcagg
    13141 cacttggatt tggtttccgt tgtggatttc ttggacttct ccatatggat gttattcagg
    13201 aacgtttaga gcgtgagttc aatattgacc tcatcatgac agctccgtct gttatttaca
    13261 aagttaattt gaccgacggt gagtctatgg atgtgtctaa cccatctgag tttccagacc
    13321 caactaagat tgcgaccatt gaagagcctt atgtcaaggc gcaaatcatg gtaccacagg
    13381 agttcgtcgg agcagtaatg gagctagctc agcgtaagcg tggggacttt gtgactatgg
    13441 actatattga tgataaccgt gtcaatgtta tctatcaaat tcctcttgct gaaattgtct
    13501 ttgacttctt tgataaactt aagtcttcga cacgtggtta tgcaagcttt gactacgaat
    13561 tgtcagaata tcgcccatct aagctggtga aaatggatat tcttctcaat ggagataagg
    13621 tggatgccct cagctttatc gttcacaagg actttgccta cgaacgtggg aaactcatcg
    13681 ttgataaact caagaaaatc atccctcgcc aacaatttga agttccaatc caagcggcta
    13741 ttggacacaa gattgtcgct cgtactgata tcaaggccct tcgtaagaac gtacttgcta
    13801 aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct tgaaaaacaa aaagctggta
    13861 agaaacgcat gaaatccatc ggatcagttg aagttccgca agaagccttc ctcagcgtct
    13921 tgagtatgga tgaagaataa gttatcagaa atgcctttcc ttgttcacag gaaatttata
    13981 taagaatcaa tagtaaagca ggcttagatg gtctgctttt ttagttttta tactcttcga
    14041 aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt atggttactg acttcgttag
    14101 tttcatctac aacctcaaaa tcatgttttg agctgacttc gtcagtttca tctacaacct
    14161 caaaactgtg ttttgagtaa cctgcggcta gcttcctagt ttgctctttg attttcattg
    14221 agtattagaa cagaaaaatg cttggagtat ttgtttgtgt atttattttt atataacaaa
    14281 ctataaacaa aacaaaaata taaaaaagag acaaaaaaag aacagaaagt aattaacaac
    14341 gatttcatat agtgttatac ttatggcata aagttaatgg aaagaaggga aaaccttatg
    14401 gtattagatt atttctttga caaaaacctt gtgttttgct tagaagcgga taatcaagaa
    14461 caactctttg atcaggtagc aagcttgttg gaagaacgag aaattgtcac tcctacttat
    14521 cgtgaagcct tgatcacgcg tgaaaagtca tttccaactg gtttagatat ggaatttcta
    14581 ggaaaggact tgccaaatgt agcgattcct cacacagata ttgttcataa tctagctgag
    14641 aaagtggtgg ttgttcgatt agaaaaacca gtaacttttc acaatatgat agctcccgat
    14701 aaggaagtag aagtatccct actcttcttt atcattacta attcaagttc aagtcaaacg
    14761 aacattcttg ctcagttgat gaacttcttc acaggaaatg gacatcttga agacctatca
    14821 aaaatttccg aaccagaaaa actttatgct tatatagatg aagcaatcgc ttaatcttgt
    14881 ttattaaaaa ataaaatcgg aggaagtcta tatgattaaa attcttgctg cctgcggtgc
    14941 aggtgttaac tcaagtcacc aaattaaaag tgctctagaa gaagaacttt caaaccgtgg
    15001 ttacgatgtt cactgtgatg cagttatggt gaaagatgta aacgaagacc ttatgaaagg
    15061 ttacgatatc tttacaccaa tcgctgcaac agaccttggt tttgaaccag gtatcccagt
    15121 tatcgaagct gggccaatct tattctgtat cccagcaatg agcgttccag tatttgacaa
    15181 tattagactt cctgcgaaat aaaatatggt atagtagttc tatgaatgat gaagcaagta
    15241 aacaactaac tgatgcacga tttaagcgtc ttgttggtgt tcagcgcacg acttttgaag
    15301 agatgttagc tgtattaaaa acagcttatc aacttaaaca cgcaaaaggt ggacgaaaac
    15361 ctaaattaag cctagaagac cttcttatgg ccactcttca atatgtgcga gaatatcgaa
    15421 cttatgaaga aattgcggct gattttggta tccacgaaag caacttactc cgtcggagct
    15481 aatgggttga agtaactctt gttcaaagtg gttttacgat ttcaagaact cctctcagtt
    15541 ctgaggacac ggtaatgatt gatgcgacgg aagtacaaat caatcgccct aaaaaagaat
    15601 tagcgaatga ttctggtaaa aagaaatgcc acgctatgaa ggctcaagcg attgtcacaa
    15661 gtcaagggag attgtttctt tggatatcac tgtgaactat tgtcatgata tgaagttgtt
    15721 caaaatgagt cgcagaaata tcggacaagc tggtaaaatc ttggctgaca gtggttatca
    15781 agggctcatg aagatatatc ctcaagtaca aactccacgt aaatccagca aactcaagcc
    15841 gctaacagtt gaagataaaa cctataacca tgcgctatct aaggagagaa gcaaggttga
    15901 gaacatcttt gccaaagtaa aaacgtttaa aatgatttca acaacctatc gaaatcatcg
    15961 taaacgcttc ggattacgaa tgaatttgat tgctggcatt atcaatcatg aactaggatt
    16021 ctagttttgc aggaagtcta ataaagaaac tagcaaggtc aggccttact ttattggtgg
    16081 acatccagga tttaattgtc ctctacttga tgatgaagtc tatgaagatt attatctaga
    16141 gtttgagaaa gaagagactt gctctgttcc acgtcctttc ccagaaacag gtatgttgga
    16201 tttccaagat agaagtccat ggctagaggg acaaaaagaa atagatctta gttatgatct
    16261 tttcagcaaa gatgcagtga ctttggatga attgcaatct cgaacaattg cccttcgttc
    16321 tcttaaacat gataggggat tgaaagtgca ttttgcagaa tttccaaacc tcatcatctg
    16381 gtcaactttg aacaagggac ctttcattac ctttgaacca tggtctggct tgtcaacatt
    16441 ccttgaagaa ggagatcatt tagaagataa gaagaatgtt tgtctcttag aagccaatca
    16501 ggttgaagaa ttagggtttg agatagaagt tttataaaaa agtaaaaaat aaataacaaa
    16561 aacaaacaca aactgttgac ttcttcaaac aatagtagta tattatgttt gtgaggacta
    16621 attgactgtt ttttaaagac agccaataca ctgctggaat ccagcataga aaaaataaaa
    16681 aggagtatac aatatgtcta ttgttatcgg tgcagatgct gcaggtttga gattgaaaga
    16741 agttgtgaaa gacttcttag aaaaagaaaa cttccacctt gtggatgtta cagctgaagg
    16801 tcaagacttt gttgatgtga ctctcgctgt tgctgcagaa gtaaacaaag aagaacaaaa
    16861 ccttggtatc gtgattgatg cttatggagc tggtccattt atggttgcaa ctaagatcaa
    16921 aggaatggtt gctgcagaag tttctgatga acgttcagct tatatgactc gtggccacaa
    16981 caactcacgt atgatcacta tgggtgcaca acttgttggt gatgaattgg ctaaaaacat
    17041 cgctaaagga tttgttaacg gtaaatacga tggtggacgt catcaaatcc gggtcgacat
    17101 gttgaacaaa atgggctaat tagattacag taagagaggt aagttaaaaa tgagaattgc
    17161 aattggatgc gaccacatcg taacagatga aaaaatggcg gtttcagaat ttttgaaatc
    17221 aaaaggatat gaagtcattg actttggtac atatgaccat acacggactc actacccaat
    17281 ctttggtaaa aaagtagggg aagctgtaac tagcggccaa gctgatcttg gggtatgtat
    17341 ctgtggtact ggtgttggta tcaacaacgc tgtaaataaa gttccaggtg ttcgttctgc
    17401 cttggttcgt gatatgacaa cagcccttta tgctaaagaa caattgaacg ctaacgttat
    17461 cggctttggt ggtaagatta ctggtgaatt gcttatgtgt gatatcatcg aagctttcat
    17521 tcatgctgaa tacaaaccat ctgaagaaaa caagaaattg attgcgaaaa ttgaacacct
    17581 tgaaagtcac aatgctcaac aaacagacgc aaacttcttt acagaattcc ttgaaaaatg
    17641 ggatcgcgga gaataccacg actaagaggt gacctatgat tttaacagtc acaatgaacc
    17701 catccattga tatttcctat cccttggatg agttgaagat tgatactgtc aatcgtgtgg
    17761 tggatgtaac caaaacggct ggtggtaagg gactcaatgt tacccgagta ctttcagaat
    17821 ttggcgattc tgttcttgct actggtttag tgggtggcaa acttggtgag tttttggttg
    17881 aacatatcga taatcaagta aagaaagatt tcttctcaat tcagggagaa actcgtaact
    17941 gtatcgctat tctccacgga gacaaccaaa cagaagttct tgaaaaaggt cctgaagtat
    18001 tggaacagga aggtcaagac tttttggaac atttcaaaaa actcttggag tcagttgaag
    18061 tagtggccat ctcaggtagt ctgccagctg gccttccagt tgattactat gcgagcttgg
    18121 tagaacttgc taatcaagct ggcaagcctg tagtcttgga ctgctcaggt gcagcacttc
    18181 aggctgttct tgaatcaccc cataaaccaa cagtcatcaa accaaataat gaagaattgt
    18241 ctcagcttct tggaagagaa gtttctgagg atttggatga attaaaagaa gtacttcaag
    18301 aacctttgtt tgcagggatt gaatggatta tcgtttcact tggtgccaac ggtacttttg
    18361 ccaaacatgg tgacactttc tacaaggtag atattcctag aattcaggtg gtaaatcctg
    18421 ttggatctgg agactctact gtggcaggaa tttcttcagg acttcttcac aaagaatcgg
    18481 atgcagaatt actcatcaag gcaaatgtcc ttggtatgct caatgctcaa gaaaaaatga
    18541 ctggtcatgt caacatggcc aactatcaag ctctatatga tcaattaata gtaaaagagg
    18601 tataaaatgg ctttaacaga acaaaaacgt gtacgcttag aaaaactttc tgatgaaaat
    18661 ggtatcatct cagctcttgc atttgaccaa cgtggtgctt tgaaacgcct catggctcaa
    18721 caccaaacag aagaaccaac tgtggcccaa atggaagaac ttaaagtctt ggtagcagat
    18781 gaattgacta aatacgcttc atctatgctt cttgaccctg agtatggact tccagcaact
    18841 aaagctcttg atgaaaaagc tggtcttctc cttgcttatg aaaaaacagg ttatgacaca
    18901 acaagcacaa aacgcttgcc agactgcttg gatgtttggt ctgcaaaacg tattaaagaa
    18961 gaaggtgcag atgcagttaa attcttgctt tactatgatg tagatagctc agacgaactc
    19021 aatcaagaaa aacaagccta catcgaacgc atcggttctg agtgtgtggc tgaagatatc
    19081 ccattcttcc ttgaaatcct tgcttacgat gaaaaaattg cggatgcagg ttctgtagaa
    19141 tacgcgaaag taaaaccaca caaagttatc ggcgctatga aagtcttttc agacccacgc
    19201 tttaacattg atgtcttgaa agttgaagtt cctgttaaca ttaaatatgt tgaaggcttc
    19261 gctgaaggtg aagtagttta tacacgtgaa gaagcagcag ccttcttcaa agcgcaagat
    19321 gaagcaacga acttgccata catctacttg agtgctggtg tatcagctaa actcttccaa
    19381 gatactcttg tatttgctca tgaatcaggt gcaaacttta acggagttct ttgtggccgt
    19441 gctacatggg cagggtcagt tgaagcttac atcaaagatg gtgaagcagc agctcgcgaa
    19501 tggcttcgca caactggatt tgaaaacatt gatgagctca ataaagttct tcaaacaaca
    19561 gcgacttcat ggaaagaacg tgtgtaagaa agtcctccta gtttaggaac atgaatctaa
    19621 aaaaatttaa aaaaagttgt atgtaaaggt ttacaaaaca accgacttgt gctatactta
    19681 aatcacaagt taatacaagg tgagtgttac taagtaatat taggcatgat cataggtgaa
    19741 ttagaaatca gctgattttc tagttcattt gtggtcattt tttgtactca tataccttta
    19801 agatataaaa ggaggttgac atgtatcgaa ttctaaatcc aatgaatcac aatgtctcgc
    19861 ttgtcagaaa tgataaggga gaagaggtga ttataattgg taaggggatt gcattcggaa
    19921 aaaggaaggg ggatttgatt gctgaaaatc aggttgagaa aatctttcgg atgaagaccg
    19981 aagagtccag agaaaacttt atggctcttc tcaaagatgt tccgcttgat tttatcacag
    20041 tgacctatga aatcattgat aagctatcaa agaaatatca ttatccgatt caagagtatc
    20101 tctatgtaac cttgacagat catatttact gttcttatca agctctaact caaggaaggt
    20161 acaaggatag taatctgccg gatatttccg ctaagtatcc tgtcgctttt caaatcgcaa
    20221 atgaagcttt tgaaatttac cgtcagaagc tagcagatca ttttcctgag gacgagatta
    20281 ttcggattgc ttatcatttc atcaatgctg aaggtgaaaa tgaagtggaa cttgtggagt
    20341 cgattgataa gaggaaagaa attctcagga atgttgaaga agtgctaaag ggttatgcaa
    20401 ttcaacgaac caaaaaaaat aatcatttct atgatcgctt tatgattcat ttgaattatt
    20461 tcttggatta tttagacaga tctagagatg ataaccaatc acttctggat atggaagatc
    20521 atattaaaca atcctatcca aaagccttcg agattggttc caagatctat gatgtgatta
    20581 cgcaacatac gggtcttgat ttgtataaaa gtgaacgagt ttatctagtt ctacatatcc
    20641 aacgtttatt gtcataaaaa tttatttaaa actatataag gagaattcta tcatgaatag
    20701 agaagaagta acattgttag gttttgaaat cgtagcctat gctggcgatg ctcgttcaaa
    20761 actattggaa gccttgaagg gtgctgaagc tggtgatttt gaaaaagcgg acgctctggt
    20821 agaggaagct ggtagctgta ttgcagaggc tcaccacgcg caaacaagtc tattgactaa
    20881 ggaagcttct ggtgaggact tagcgtatag tgtgaccatg atgcatggtc aagatcactt
    20941 gatgacaact atcttgttaa aagacctaat gcaccattta attgaacttt acaagagagg
    21001 agttaaataa tgaacaaact aattgcattt atcgagaaag gaaagccttt ctttgagaaa
    21061 ctatctcgta atatctatct tcgtgctatt cgtgatggtt tcattgcagg tatgcctgtt
    21121 attctcttct caagtatctt tatcttgatt gcctttgtac caaactcatg gggctttaaa
    21181 tggtctgatg aagttgtagc ctttctgatg aaaccttata gctattctat gggtattctg
    21241 gctctcttgg tagctggtac aacagctaag tcattgactg actcagtaaa ccggagcatg
    21301 gaaaaaacca atcaaatcaa ctatatgtca acattgttgg cagcaattgt tggtttgttg
    21361 atgttggcag ctgatcctat cgaaagtggt ctagctactg gattcttggg gacaaaaggt
    21421 ttgctttcag ccttccttgc tgccttcgtt actgtagcca tctataaggt ttgtgttaag
    21481 aacaacgtca ctattcgtat gcctgacgaa gttccaccaa atatctcaca agtctttaaa
    21541 gatgtgattc cattcactct ctcagttgtt tcactttatg ctcttgattt actagctcgt
    21601 cattttgttg gtgcaagcgt agctgaatca atcggtaaat tctttgcacc actcttctca
    21661 gcagcagacg gataccttgg tattaccatt atctttggtg cctttgcctt cttctggttt
    21721 gtgggtattc atggtccatc tattgttgaa cctgctatcg cagcgattac ctatgcaaat
    21781 gctgaagtca acttgaacct tctccaacaa ggtatgcatg ctgataaaat ccttacttca
    21841 ggaactcaaa tgtttatcgt tactatggga ggtactggtg cgacactggt tgttccattc
    21901 atgttcatgt ggttaacaaa atcaaaacgt aaccgtgcaa tcggacgtgc ttcagtagtt
    21961 ccaactttct ttggtgtaaa tgaaccaatc ttgtttggtg caccacttgt attaaatcca
    22021 atcttcttca ttccatttat ctttgctcca atcgcaaacg tatggatttt caaattcttt
    22081 attgaaactc ttggaatgaa ctcattcact gctaatctac catggacaac tccagctcca
    22141 ctaggtctag ttcttggaac taacttccaa gtgctatcat tcattcttgc tgcccttcta
    22201 atcgtggttg acgttgtcat ttactatcca ttccttaagg tctatgatga acaaattctt
    22261 gaagaagaac gttcaggtaa gtctaatgat gaattgaaag aaaaagttgc tgcaaacttc
    22321 aacactgcaa aagcggatgc tattcttgaa aaagcgggtg tagaagcagc acaaaataca
    22381 atcactaaag aaacaaatgt cctcgttctc tgtgcaggtg gaggaacaag tggtctcctt
    22441 gcaaatgctt tgaataaggc agcagcagaa tacaatgtcc ctgtgaaagc agcagcaggc
    22501 ggctatggtg ctcaccgtga aatgttacca gagtttgatc ttgttatcct tgcccctcaa
    22561 gttgcttcaa actttgaaga tatgaaagca gaaacagata agctcggtat taaactagcg
    22621 aaaacagaag gcgctcaata catcaaatta actcgtgatg gaaaaggtgc tcttgcattc
    22681 gtacaagcgc aattcgatta aggctagaga ctctgaaata gtctcccatc gttacggaaa
    22741 tcgctatggc gaatttccta ttattaattc gtcggtaaaa agatatcgtt tttacctcct
    22801 catgtcacaa ttcggtgact tggtacaaga agtgagatgg agaaggatgg ctcactgact
    22861 cctctcctct cacttttact ttatttaaat caagaaatag gtgaaaaaaa tgacaaaaac
    22921 acttccaaaa gactttattt ttggtggcgc aacagctgct tatcaagcag aaggtgctac
    22981 acatactgat ggaaaaggac cagttgcttg ggataaatat cttgaggata actactggta
    23041 cactgccgaa ccagctagtg atttttacaa tcgatatcca gttgacctca agctagcaga
    23101 agagtatggt gtcaatggta ttcgaatttc tattgcttgg tcacgtattt tcccgactgg
    23161 ttacggccaa gtaaatgcta aaggtgttga gttttatcat aatttatttg cagagtgtca
    23221 caaacgtcat gttgagcctt ttgtaactct tcatcacttt gacacgccag aagctctcca
    23281 ctcaaatgga gacttcttaa accgtgaaaa tatcgaacat tttgtagact acgctgcctt
    23341 ctgttttgaa gaatttccag aagtaaacta ttggacaacc tttaatgaaa ttggaccaat
    23401 cggtgatggt caatatttgg ttgggaaatt ccctccaggt atccagtacg accttgccaa
    23461 agtctttcaa tcacaccaca atatgatggt gtctcatgca cgcgcggtaa aattgtacaa
    23521 agagaaaggc tataaagggg aaattggtgt tgttcacgcc ctgccaacta aatatcctct
    23581 agatcctgaa aatccagcag atgttcgtgc agctgagttg gaagatatca tccacaataa
    23641 attcatctta gacgcaactt atctaggtcg ctattcagct gaaaccatgg aaggtgtcaa
    23701 ccatatctta ttagtcaatg gtggtagttt ggatcttcgt gaagaagatt ttacagcatt
    23761 agaagctgca aaagacttga atgatttcct aggaatcaac tactatatga gtgactggat
    23821 ggaagccttt gatggagaaa ctgaaattat ccataatggt aaaggtgaaa aaggaagctc
    23881 taagtatcaa atcaaaggtg ttggtcgtcg tgtagctcct gactatgtac cacgcacgga
    23941 ttgggattgg attatctacc ctcaaggttt gtatgaccaa atcatgcgtg tgaagaaaga
    24001 ttatcctaac tacaagaaga tttacatcac tgaaaatggt ctcggctata aagatgagtt
    24061 cgttgataac actgtttacg atgatggtcg tattgattac gtgaagcaac acttggaggt
    24121 tttatctgat gcgattgcag atggagctaa tgtaaaaggt tacttcattt ggtcattaat
    24181 ggatgtcttc tcatggtcaa acggttatga gaaacgttat ggtctcttct acgtagattt
    24241 tgaaactcaa gaacgttatc ctaagaaatc agctcactgg tacaagaaag tagcggaaac
    24301 tcagattata gactagtaga attagtcatt agatatagaa ttttagtgag tcaaaaagat
    24361 gttcaaagat tttatccaat ctatttatga aaaaaagttt atattataaa tttcgaaaaa
    24421 tgctctcaaa taccgtgttt gacgagtgaa gaattgaaag tcttggaaaa tggtatgtct
    24481 cgactggtaa agaatggatt tgtcattcag atgatgagct ggaagaattt aaaaatctat
    24541 ttttaaattt tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc
    24601 cgtttcaaca atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgta
    24661 aaactcttat ctaatcacgt tgcttatact caatgaaaat catagaaaaa agcatagtat
    24721 caggtgttga aacacctgat actatgcttt ttattgtggg aagatttact ttttttcttc
    24781 tgaaattgag ttgttaccca ggctctttca gtttattaag gcttgatgac tttaatgtgt
    24841 ttagatagct taaaaaggat tgaatcactt agtttagaat ctgaaacaat agtatcaaga
    24901 tttgatatat tataaaaagt ataaaaatca aacttattga acttactatg atctgcgagt
    24961 aaatattttt tattagaatt atttaaagcg atgcgttgag cctctccctc ttcctcgcta
    25021 aaagtagcta gagctccgtt ttgaatacca ttacagctaa cgaaagcttt agaaaattgg
    25081 agattagaga gattttgtag ggtcaatgtg ccaacaaaag cacctgtaat atcgcgataa
    25141 tttccaccta tcaaaatcaa atctgttaat tttcgttcgc ttaaaatcag aaaaacaggt
    25201 agactgttgg ttacgacgcg gatattgtca ataggcaact cacgcgcaaa aaactctaat
    25261 gttgttcctg gtccaatgaa aatagtttct ctttcttcta ctagactgcc tgcaaaatgg
    25321 gctatttctt gtttttctgc cgtttggagg gcttgttttt caatatttga tcgctcatta
    25381 gtcaaaaggg agttggttcg aagtttttca gctccaccat gcacacgaat cagcaaatct
    25441 ttatcagcta attcctgtaa atagcgcctt gcagtcatat ctgaaacggc tatttcgtcc
    25501 ataatctgtt taactgttat ggttccttta ctatttacta tctctaaaat tttggttaat
    25561 ttttcttgtt tgagcatatt atcacctcgt ttcctactac tatcttacca taaactagct
    25621 catcattcaa atacaaaaac aacaaaataa aacaaaaaca aaaatatcga agtttatttt
    25681 caaaactttc gatatttttg tttttgtttt attttgttgt ttctagttta ctttttgatg
    25741 gttaagagtg gtggaga
//
LOCUS       DAVLZS010000027        25692 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLZS010000027 DAVLZS010000000
VERSION     DAVLZS010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.027"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..345
                     /locus_tag="VYO88_001228"
     CDS             <1..345
                     /locus_tag="VYO88_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1719326.1"
                     /translation="ISLVAGLTNGELIAPMTYEETMTSDFFEAWFQKFLLPTLTTPSV
                     IIMDNARFHRMGKLELLCEEFGYNFLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNT
                     FYEALLSCSCFN"
     gene            complement(552..2810)
                     /locus_tag="VYO88_001229"
     CDS             complement(552..2810)
                     /locus_tag="VYO88_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1719327.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3039..3269)
                     /locus_tag="VYO88_001230"
     CDS             complement(3039..3269)
                     /locus_tag="VYO88_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1719328.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3459..4142
                     /locus_tag="VYO88_001231"
     CDS             3459..4142
                     /locus_tag="VYO88_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1719329.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4142..4876
                     /locus_tag="VYO88_001232"
     CDS             4142..4876
                     /locus_tag="VYO88_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1719330.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5030..5887
                     /locus_tag="VYO88_001233"
     CDS             5030..5887
                     /locus_tag="VYO88_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1719331.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6024..6845
                     /locus_tag="VYO88_001234"
     CDS             6024..6845
                     /locus_tag="VYO88_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEV1719332.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            6859..7731
                     /locus_tag="VYO88_001235"
     CDS             6859..7731
                     /locus_tag="VYO88_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1719333.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            8013..8696
                     /gene="rpiA"
                     /locus_tag="VYO88_001236"
     CDS             8013..8696
                     /gene="rpiA"
                     /locus_tag="VYO88_001236"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1719334.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            8710..9921
                     /locus_tag="VYO88_001237"
     CDS             8710..9921
                     /locus_tag="VYO88_001237"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1719335.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9923..10465
                     /locus_tag="VYO88_001238"
     CDS             9923..10465
                     /locus_tag="VYO88_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1719336.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKVQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            10481..11290
                     /locus_tag="VYO88_001239"
     CDS             10481..11290
                     /locus_tag="VYO88_001239"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1719337.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKILALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            12537..13394
                     /locus_tag="VYO88_001240"
     CDS             12537..13394
                     /locus_tag="VYO88_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1719338.1"
                     /translation="MSADLVLLGGNKPAQADDIRKVVGELAKDISITKLYMTGHSLGC
                     YLAQIAAVEAYQKYPDFYNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAV
                     SGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQA
                     TLDKHGYRDPKLDKVRFFKKQALPRSSSQPSAELMENIALGKQVTQSSTVFGGDARRA
                     VDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINIYNRTDTAQDRLANFDVIL
                     LDSSGKEIE"
     gene            13419..13931
                     /locus_tag="VYO88_001241"
     CDS             13419..13931
                     /locus_tag="VYO88_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1719339.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            14588..15298
                     /gene="deoD"
                     /locus_tag="VYO88_001242"
     CDS             14588..15298
                     /gene="deoD"
                     /locus_tag="VYO88_001242"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1719340.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(15321..15845)
                     /locus_tag="VYO88_001243"
     CDS             complement(15321..15845)
                     /locus_tag="VYO88_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV1719341.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(15898..16134)
                     /locus_tag="VYO88_001244"
     CDS             complement(15898..16134)
                     /locus_tag="VYO88_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1719342.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(16202..17122)
                     /locus_tag="VYO88_001245"
     CDS             complement(16202..17122)
                     /locus_tag="VYO88_001245"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1719343.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            17312..17679
                     /locus_tag="VYO88_001246"
                     /pseudo
     CDS             17312..17679
                     /locus_tag="VYO88_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17895..18476
                     /locus_tag="VYO88_001247"
     CDS             17895..18476
                     /locus_tag="VYO88_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1719344.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLYVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            18473..19750
                     /locus_tag="VYO88_001248"
     CDS             18473..19750
                     /locus_tag="VYO88_001248"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1719345.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            19768..20430
                     /gene="deoC"
                     /locus_tag="VYO88_001249"
     CDS             19768..20430
                     /gene="deoC"
                     /locus_tag="VYO88_001249"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1719346.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            20417..20806
                     /locus_tag="VYO88_001250"
     CDS             20417..20806
                     /locus_tag="VYO88_001250"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1719347.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            20896..21948
                     /locus_tag="VYO88_001251"
     CDS             20896..21948
                     /locus_tag="VYO88_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1719348.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            22092..23627
                     /locus_tag="VYO88_001252"
     CDS             22092..23627
                     /locus_tag="VYO88_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719349.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            23620..24678
                     /locus_tag="VYO88_001253"
     CDS             23620..24678
                     /locus_tag="VYO88_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1719350.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGSVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            24681..25637
                     /locus_tag="VYO88_001254"
     CDS             24681..25637
                     /locus_tag="VYO88_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1719351.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         7525 a         4599 c         5812 g         7756 t
ORIGIN      
        1 atttctttgg ttgcaggtct aacaaatggt gagttaatcg ctccaatgac ttacgaagag
       61 acgatgacga gcgacttttt tgaagcttgg tttcagaagt ttctcttacc aacattaacc
      121 acaccatcgg ttattattat ggataatgca agattccata gaatgggtaa gttagaactc
      181 ttgtgtgaag agtttgggta taacttttta cctcttcctc cctactcacc tgagtacaat
      241 cctattgaga aaacatgggc tcatatcaaa aagcacctca aaaaggtatt accaagttgc
      301 aatacctttt atgaggctct tttgtcttgt tcttgtttca attgactata gcagattgaa
      361 ataagatgag aacaaatcga ttgggaaagt aaaattaatt tctataaatg ttttagcaat
      421 tgtttcgtac tatttcagat tcagtctact atatatcata atggacaaag ggcaagctgt
      481 caagaaatta cagttatttt agtaaaaaaa gaagcagaaa aatttcattt tctactcctt
      541 ttctatagga tttatttttc tttttcagaa cttttaactt cagctttttt ggcagattta
      601 atctgaatgt ttcccttgct agtcataact gctttgagat ctttttcgct tggattttca
      661 aggtagtagt cagtgattgt gtcctcaata tagtcttgaa tagtccgacg aagtgggcgt
      721 gctcccattt ttggatcata acctaggtca accaactttt ccttgacctt gtcagttaca
      781 tccaaacgaa tgttgttgct agagaggcgc ttgttaacat ctgctagcat gagctcgaca
      841 atctgaagga ggttatcctt gctgagagcc ttaaattcga taatgccatc aaaacggttc
      901 ataaactctg ggctaaagaa gttaccgagt tcaccgagga cagaattggt acgtccttct
      961 ctagcagcac caaatccaac gctagcttcg gtctttcctg tacctgcatt tgaggtcatg
     1021 ataatgatgg catccttgaa gctaacggtg cgtccttgcc cgtctgtcaa acgaccatcg
     1081 tccaagactt gaagaaacat gtgcataaca tctgggtgag ctttttccac ttcatcgaga
     1141 aggatgagag aatacggatt gtggcgaact ttttcagtta attgaccagc ctcatcatag
     1201 ccaacataac ctggaggagc gccgaccaac ttagccacac tatgtttttc catgtattca
     1261 ctcatatcaa agcgaatcat actatcagca gaaccaaaaa gttcgatagc cagttgtttg
     1321 gaaagttctg tcttaccgac accagttggt ccaacgaaga ggaagcttcc gattgggcgg
     1381 ttaggggtac caagtccgac acgattacgg cgaatagcct tggcaatctt atcgactgca
     1441 tcatcttggc caataacatg agacttgaga tcttcggcta gatggatgag ttgagattgt
     1501 tctttctctt tcaaatcacc aacagggata ttggttttct gctcgataat gtgctcaata
     1561 gttttctcgc tgatgatagg agtatcctgg tctgtgatct ttttcttttg catttcctta
     1621 tacttggcaa tctggtcgcg gaagtaggcc gccttctcaa aatcttcttc tcgtgtagct
     1681 tgagacttga gattttcagc ctcaatcaag cgctgatcaa ttactttagg atccacaaaa
     1741 ttcaaggtca agttcatctt agaaccagct tcatctagga ggtcaatggc cttgtcaggc
     1801 aagaagcgat cttggatgta gcgattggaa agagttgcag ctgcttcaat cgcagcatcg
     1861 gtatattgaa cgtggtggta atcttcgtat ttcttttgaa tccctttgag aatagtgatt
     1921 gtttcatcca ccgttggttc atcgacttta acaggctgca tacgacgctc gagggcagca
     1981 tccttttcaa tgatacggta ttcattgagg gtagtagcac cgactagttg cagttctcca
     2041 cgagcaaggg ctggcttgag gatatttcct gcgtccatat taccatcact cgcagaacca
     2101 gcaccaacaa tttcatggat ttcatcgata aagaggatga tgtcttcacg tttgcgaatt
     2161 tcttccatga gtttttgcat gcgttcttca aattgtcctc gaatccccgt tccttgaact
     2221 aagctaacca catccagacg gatgacttgt ttaccttgga gtttatgtgg cacatcgcca
     2281 tcgacaattt tctgagctag accttcgaca acggccgttt ttccgacacc aggttcaccg
     2341 ataaggacag gattattctt ggttctacga ttgagaatct cgatgacacg gataatctca
     2401 tcgtcgcgcc caataacggg gtcaatgtct ccacgacggg caatttcagt tacattaata
     2461 ccaaattctt ccagcaggcc tttttcttgg ctaggtggcg gagtttgagc agatccacga
     2521 ttttgggaac cataaccgcc gtttccaccg taacctccac ctgattgggt tgggggaata
     2581 ggaggagtat tgctagaagg tctgaaattg tttagatcat tgaagaaatc accaaaggga
     2641 tcgaagtcac gattgttcag atccgtcata cctttgaaga ggctattgtt aggatctgtt
     2701 ttgataatct tatagcagtt ttgacagagg tcaatttgtt tttgttttcc attgagattg
     2761 gtgtaaagat gaattgttga gtcgttaatt ttacagtttt gacaaagcat acatctacct
     2821 catttctttc tttagcctga cttgtttaaa ggtcaaaaat agtcaaattc tatactctca
     2881 ttataacagg attggggggt aaagcaagta aaaagattga agctttgaga agttgttaca
     2941 atgaaaattt ttgtgaattt ggactataaa aaaatcctat ttgtgagaca aaaaggattt
     3001 tacttagaca tgcagggaca atcccagctt gttttagatt agtagagaag ttcgtaaatt
     3061 tccattgcga ttaagtcaat gctatcaaac gtatacgttt cgcgatcttc tacgtcacga
     3121 agggtaaaga ttgggccgtt ttcttcgtcg tggctgtacg caacttctgc aacaacaact
     3181 ccttcgcgtt caaaattacg ttttaaattt ccgccatcgt ttgccattgc ttcaaggcgg
     3241 ttgatgattc taaccaaatg tgattccatt ttgattctcc ttcatttctt atcgttacta
     3301 ttttaccata aaggaggcca acttgactag aaaaaactaa gatttctcgt taattctgct
     3361 agtttaaaga tttttaaata aattggataa aaaatttaaa ttttaattca aaacatgtta
     3421 taatcataca gtattctatt ttagaaagca gtgtgactat gaatttttct tttttaccta
     3481 agtatttacc ttattttaac tatggggctg ttgtgacgat tcttatttct atctgtgtta
     3541 tctttttggg aactattttg ggtgttgtct tggcttttgg gcaacgttca aagtttaaac
     3601 cgcttgtttg gttggccaac ttgtacgttt ggattttccg tgggacaccg atgatggttc
     3661 aaattatgat tgcctttgct cttatgcata tcaatgctcc gactattcag attggaattt
     3721 taggtgttga tttttcgcgt ctgattccag ggattttgat tatctctatg aatagtggtg
     3781 cttatgtttc ggagactgtt cgtgccggaa tcaatgcggt tccaaaaggt cagctagagg
     3841 cggcttattc gctagggatt cgtcctaaaa atgcgatgcg ttatgtgatt ttgccacaag
     3901 cagtcaaaaa tatcttgcca gcattgggga acgaatttat caccattatc aaggacagct
     3961 ccctcttatc agctattggg gtcatggagt tgtggaatgg ggctacaaca gtttctacaa
     4021 caacctatct acctttaaca ccacttttat ttgcagcatt ttactacttg attatgacct
     4081 ctattctgac agtagccttg aaagcttttg aaaaacatat gggacaagga gataagaaat
     4141 aatgacagaa accttgataa aaattgaaaa tttacataaa tcttttggaa agaatgaagt
     4201 attgaagggc atcaacctcg agattaaaag aggagaagtt gtcgttatca tcggtccttc
     4261 agggagtggg aaatctacct tgcttcgctc tatgaatttg ttggaggaag caaccaaggg
     4321 gaagcttatc tttgagggag tcgatattac ggacaagaag aatgacctgt ttgccatgcg
     4381 tgagaagatg ggcatggttt tccaacaatt taacctcttt cctaatatga ctgtgatgga
     4441 aaatattacc ttgtcaccta tcaagactaa aggtgaaagc agggaagttg ctgagaagag
     4501 agcccaagag cttttggaaa aagttggttt gccagataag gcagacgctt atccacagag
     4561 tctgtcgggt gggcagcaac aacggattgc catcgcgcgt gggttggcta tggaaccaga
     4621 tgttttgctc tttgacgaac caacttcagc cttggatcct gaaatggtag gtgaggtatt
     4681 ggctgttatg caagaccttg ccaagtcagg gatgactatg gttatcgtaa cacatgagat
     4741 gggatttgcc cgtgaggtgg cagatcgtgt tatctttatg gcagacggtg tggttgttga
     4801 agatgggaca cctgagcaga tttttgaaca aacccaagaa caacggacta aagatttctt
     4861 gagtaaggtt ttataatcta ttttaaaatt tcaagacaag attagtgaaa agttcaacca
     4921 gagctttttc ttatagtttg aaactatagg ataacctagg aaagaagtgt tagagggcac
     4981 tagcagtttt tggtataatg gaagatattt gaaagaaaag agaagtgata tgacacagat
     5041 tattgatggg aaagctttag cggccaaatt gcaggggcag ttggctgaaa agactgcaaa
     5101 attaaaggaa gaaacagctc tagtgcctgg tttggtagtg attttggttg gggataatcc
     5161 agccagccaa gtctacgttc gcaacaagga gaggtcagct cttgcggctg gttcccgtag
     5221 cgaagtagtg cgagttccag agaccattac tcaagaggaa ttgttagacc tgattgctaa
     5281 atacaatcag gatccagctt ggcatgggat tttggttcag ttgccattac caaaacacat
     5341 tgatgaagag gcggttctat tggctattga cccagaaaag gatgtggatg gtttccatcc
     5401 tctaaatatg ggacgccttt ggtctggaca tccagtcatg attccatcaa cacctgcagg
     5461 aattatggaa atgtttcatg aatatgggat tgaattagaa ggtaaaaatg cggttgtcat
     5521 cggtcgttct aatatcgttg gaaaacccat ggctcagctt cttttggcca agaatgcaac
     5581 agtgactttg acccactcac gcacccataa tcttgctaag gtggctgcta aagcagatat
     5641 tctggtggtc gcaatcggtc gtgccaagtt tgtgactgct gactttgtca aaccaggtgc
     5701 ggtagtcatt gacgttggga tgaatcgtga tgaaaatggt aagctctgtg gggatgtgga
     5761 ttatgaggca gttgccccac ttgctagcta tattacgcca gtccctggag gtgtcggccc
     5821 tatgaccatt actatgctga tggagcaaac ttatcaagca gcacttcgga cattggatag
     5881 aaaataagag aaaaatcgct gaagagagtg tattttctat agctatattt aaaatggcag
     5941 aaatgaatat taaattttag atataagatt acaaaaggag gtctgcgcct cctttttgtt
     6001 gtataatgga gtgaggtgat tagatgattt taaaaattta taatagggaa tatagtttac
     6061 aatgggatgg aatatactac ctagcactaa ttgattatcc aaatattcaa gagtgggaat
     6121 tagaaaaaat tgctaaattt atagcttacg aaaaacttca taaacgtcaa acaagtattg
     6181 agtgtgctga ttcttgttta aaaaaagaaa ttttagatta catctgtcag catccctttc
     6241 tgccaccatt tacccctaca gataaaagag tagcctcgac ttatgatcta cataagaggt
     6301 tagtgacttc agactactgt agtcatacta cgactataga tgcagcgatt tctatcttta
     6361 aaacaggtca gctcttatct gctgtgaaag cctttaggcg agatgctgaa gagttggttt
     6421 tggatagtag aaatgctgca tcggatccga tagattattt tgattatgtc atgttagggt
     6481 ggtcaaatac aagttctggt tatcgattag cgatggagcg tttattaggt cgagctcctt
     6541 cagagaaaga attacaagac aagtttattc ctggagtgag ttttcatttt atctatacag
     6601 atttgattaa agttactggt tatatttttg atggctacca tgttgcaaaa attaaggaca
     6661 tgttgaattt atttagtgag ttgtatattt gtattattcc aactcataat aagagccaat
     6721 ttgaaaatat tattccaact aaaatacaag atagggtgca ttatcttgac tatgctggag
     6781 aagacttaga agagtggact aagaaagtct atcaagttgt tttaaaacaa tcagataaag
     6841 gatagttgag gaagaacgat gaaagtgatt gatcaagcct tactagaaaa agttattatt
     6901 gaacgttctc gtactagtca taaaggagac tatggccgtc tgctgtttct tggtggaact
     6961 tatccttatg gtggtgccat catcatggct gctttggcag ctgtaaaaag cggtgcagga
     7021 ttggtgaccg ttggaacaga tagggaaaat attccagccc tgcacagcca tttacctgag
     7081 gctatggcct tttctcttca agaccagcag ttgttaaaag agcaattgga gaaggcagaa
     7141 gttgtcttgc tggggcctgg tttacgagac gatgcttctg gagaaaatct agtaaaacag
     7201 gtctttgtta atttaagcca aaatcagatt ttgattgtag acggaggtgc cttgaccatt
     7261 cttgctagga caagtttgtc atttccctca agccagctta tcctaactcc tcaccaaaaa
     7321 gaatgggaaa aattatctgg aattacgatt gaaaagcaaa aggaagatgc aacggctagt
     7381 gttctgactt ccttccctca aggaacaatt ttggtggaga aaggcccagc tactcgtatt
     7441 tgggaagttg gccaatctga ttattaccag ttacaggttg gtggtcctta tcaggcgact
     7501 gggggaatgg gagatactct ggctgggatg atcgcaggat ttgtaggcca attccgacag
     7561 gccagtctct acgagcgtgt ggcagtagcg acccatcttc attcagccat agcccaagaa
     7621 ctatctcaag aaaattatgt ggtcttaccg acggaaatca gcaggtatct tcccaaaata
     7681 atgaaaatta tttgtcaaca agatagggta agcaaagata aacttgttta aaatagacag
     7741 ataaatctac ttccttctct taatttatga ttcttgaaat gcgcctgctt taaggctaaa
     7801 ctagacgtat caaagttaag agtttgtttt tgtaactgga aagagatgaa caaatcaaat
     7861 acataaaaga taaactcatt tttattcgtt tggtaaaaat aaaatgcata tttttaaaga
     7921 aagattgatg aaaaatgtag atttgatgtt tttacttgaa taaaaagcgg tttcatagta
     7981 aaataagaac tgagaatgat ggaggtaaat cggtggaaaa tctgaagaaa atggcaggta
     8041 tcaaggctgc tgagttcgtg agcgatggaa tggtcgttgg acttggaaca ggctcgactg
     8101 cctattattt tgtcgaagaa atcggtcgtc gtatcaagga agaaggattg cagattacag
     8161 ctgtaacaac ttctagtgtg accactaaac aggcagaagg ccttaatatc ccgctcaagt
     8221 ctattgacca agtagacttt gtcgatgtga cggttgatgg cgcggatgaa gtggatagtc
     8281 agtttaatgg aatcaaaggc ggtggtggtg cccttctcat ggaaaaggtg gtcgcaacac
     8341 catcaaaaga atacatttgg gtggtggatg aaagcaagct ggtcgaaaaa ctaggtgctt
     8401 ttaaattgcc agtagaagtg gttcagtatg gtgcagagca ggtctttcgt cattttgaac
     8461 gagctggcta caaaccaagt ttccgtgaaa aagacggcca acgttttgtg acggatatgc
     8521 agaattttat cattgacctc gccttggatg tcattgaaaa tccaattgct tttggacaag
     8581 aattggacca tgtcgttggt gttgtggagc atggtttatt caaccaaatg gtggataagg
     8641 taatcgttgc tggacgagat ggagttcaga tttcaacttc aaaaaaagga aaatagaagg
     8701 gggcataaga tgtctaaatt taatcgtatt catttggtgg tactggattc tgtaggaatc
     8761 ggtgcagcac cagatgctaa taactttgtc aatgcagggg ttccagatgg agcttctgac
     8821 acactgggac acatttcaaa aacagttggt ttgaatgtcc caaacatggc taaaataggt
     8881 cttggaaata ttcctcgtga aactcctctt aagactgtag cagctgaaag caatccaact
     8941 ggatatgcaa caaaattaga ggaagtatct cttggtaagg atactatgac tggacactgg
     9001 gaaatcatgg gactcaacat tactgagcct ttcgatactt tctggaacgg attcccagaa
     9061 gaaatcctga caaaaatcga agaattctca ggacgcaagg ttattcgtga agccaacaaa
     9121 ccttattcag gaacggctgt tatcgatgat tttggaccac gtcagatgga aactggagag
     9181 ttgattatct atacttcagc tgaccctgtt ttgcagattg ctgcccacga agacattatt
     9241 cctttggatg aattgtaccg tatctgtgaa tacgctcgtt cgattaccct tgagcgtcct
     9301 gcccttcttg gtcgcatcat tgctcgccct tatgtaggtg aaccaggtaa cttcactcgt
     9361 acggcaaacc gtcgtgactt ggctgtatct ccattttccc caactgtttt ggataaattg
     9421 aatgaggctg gtatcgatac ttatgctgtg ggtaaaatca acgatatctt taacggtgct
     9481 ggtatcaacc atgacatggg tcacaacaag tcaaatagtc atggaattga tacactattg
     9541 aagactatgg gacttgctga gtttgaaaaa ggattctcat tcacaaacct agttgacttt
     9601 gatgcccttt acggccatcg tcgtaatgct cacggttacc gtgattgctt gcatgagttt
     9661 gatgaacgct tacctgaaat tatcgcagct atgagagaga atgaccttct cttgattact
     9721 gcggaccatg gaaatgaccc aacgtatgca ggaacggatc acactcggga atatattcca
     9781 ttgttggcct atagccctgc ctttaaagga aatggtctca ttccagtagg acattttgca
     9841 gatatttcag cgactgttgc cgataacttt ggtgtggaaa ctgctatgat tggggaaagt
     9901 ttcttagata aattggtata agatgacgcg ctatgctttg ctggtgagag gtatcaatgt
     9961 tggtggtaag aataaggtcg tcatggcgga gcttcgtcaa gaattgacaa acttgggact
    10021 ggaaaaggtt gagagctaca tcaacagtgg caatattttc tttacttcga tagattccaa
    10081 agtccaattg gttgaaaagc tagagacttt ctttgcagtc cattatccat ttattcagag
    10141 cttttcttta ctgagtctag aggactttga ggcggaactt gaaaatctac cagcttggtg
    10201 gagcagagac ttggcacgaa aagattttct cttttacact gaaggtttgg atgtggacca
    10261 agtcatcgcg acagttgaaa gtttagagct gaaagatgaa gtgctttatt ttggaaaact
    10321 tgggattttc tgggggaaat tttctgaaga atcctattct aagactgcct atcataagta
    10381 cttgctgaag gtgcctttct accgccacat tactattcgt aatgctaaaa cctttgacaa
    10441 aattggtcaa atgctaaaaa aataataaag gagacacaca atgacatttt taaacaaaat
    10501 ccatgaaact gctactttcc tgaaagaaaa gggaattgca gcccctgagt tcggtctaat
    10561 ccttggatca ggacttggag aattggcaga agaaatcgaa aatccagttg tagtagacta
    10621 tgctgagatt ccaaactggg gccgttcaac agtagtcggt catgctggta aattggtata
    10681 tggtgaactg gcaggtcgca agatcttggc tcttcaaggg cgtttccatt tctatgaagg
    10741 gaatcctctg gaagtggtga ctttcccagt tcgtgtgatg aaagttcttg gatgtgaagg
    10801 tgttattgta accaatgcag ctggcggtat cggatttggt cctggtacct tgatggctat
    10861 ctcagaccat atcaacatga cggggcaaaa tccattgatg ggtgaaaact tggatgactt
    10921 tggcccacgt ttcccagata tgtctagggc ttacacacca gaataccgtg ccactgccca
    10981 tgaagtggct aaaaaactta atatcaagct tgatgaaggt gtctatatcg gagttactgg
    11041 tccgacttat gaaacaccag cagaaattcg ttcctataag acactgggag cagatgcagt
    11101 tggtatgtct acggttcctg aagttatcgt ggcagcccac tctggcttga aagttctggg
    11161 aatttcatgt atcactaact ttgcggccgg tttccaagaa gaactcaatc acgaagaagt
    11221 tgtagaagtg actgaacgtg ttaaaggtga tttcaaaggc ttgcttaaag cgattcttgc
    11281 tgaattgtaa gaaaaaagat ttaaaagggg gagtgcctct gtcttttcag gattgactgc
    11341 ctatccgtat taaagaagaa acagaggaat actatgagct tcttcctgct cttataactg
    11401 aaagaagcgg aagaataggt atgtctgatc tgatagccag cattgtgaaa gacaagattc
    11461 taggatacta gcattagctt cctagccaag cagactagta tgataaggag agatgagaat
    11521 gaattgactt tctgaatttc tcagtcttat catatatagc acaatgagat ttcgcttgag
    11581 tctgcttgta aataaacgaa aagaaagata agaaataatg aaaattggtc aacgaattat
    11641 gcgctttggc ataaaaaatt aagtatcgga gttgtatctg ttgtagtcgg ctttgatttc
    11701 tagctccagc tggaatttca gccaatgaag taaagcaaga tgtaacatct gaagtggtaa
    11761 taggtgtgct agattctaag gaggaattga aagagtcaga aaatgatgct ccaaaactag
    11821 aaactcctct tagagaggag ccaagactag ctcctcaaac gcttccggaa gcaagtgaag
    11881 ttcttgaaaa caaaagggaa gagtcaaaag tagagataac agagccagct caagactcac
    11941 ctattcttgc tcctgtagaa gaaactaaag aagaagctgt gacagaaaaa ccaacaaata
    12001 ctcgttctct aactgcagaa gatttggtga agatttccaa aggggaattg catttagaaa
    12061 atgatttgat tgatgaatct ttctatggtg aaaaagctct tgatttggaa ggggatgatg
    12121 accaggatgg catcaaaaac aaagatggta aggattatct aggatataac agtcatccct
    12181 tgctagcaga cagtgatggg gatggtttgg cagatgggga agatgataat aagaaagaat
    12241 ggtatgtcac agaccgtgat tctcttctct ttatggagtt agcttatcga gacgatgatt
    12301 atattgagaa aattttatat cataagaatc ttttccctag tctctatctt gaccgtcaag
    12361 aacacaaact catgcacaat gaattggctc ctttctggaa gatgaaaaaa gcctactata
    12421 cagatagtgg cttggatgct ttcttatttg agaccaagag cgaccttcct tatctcaaag
    12481 atggaacggt gtacatgttg gctattcgtg gaacgcgagt taatgacgcc aaggacttga
    12541 gtgcagattt ggttttatta ggtggaaata aaccagctca agcggatgat atccgcaagg
    12601 ttgttgggga attagccaag gatataagta ttactaagtt gtatatgaca ggtcattctc
    12661 ttggatgtta cctagctcag attgcagcgg ttgaagctta ccaaaaatat cctgattttt
    12721 ataaccatgt attgaggaaa gtgacaactt tcagtgctcc taaagtgatt acttccagaa
    12781 ctgtttggaa tgctaagaat ggtttctggg atgttggttt ggaaagtcgt aaattagctg
    12841 ttagtggaaa aattaagcat tatgtggttg ataatgacaa tgttgtgact cccttgattc
    12901 ataataatcg tgatattgtt acatttacag gtaattcacg ctttaaacac cgttctcgtg
    12961 gctattttga aagtccaatg aatgatattc ctaactttaa tattggtaaa caagctacct
    13021 tggataaaca tggttatcgt gatccgaaat tggataaagt gcgattcttt aagaaacagg
    13081 ctctgcctcg atcttctagt caaccaagcg ctgaactaat ggaaaatatt gccttaggaa
    13141 aacaggttac tcaaagttcg acagttttcg gaggagatgc tagaagagct gtggatggca
    13201 aagtcgatgg taactatggt cacaattctg tcactcatac aaacttccaa tctaagcctt
    13261 ggtggcaagt agatttggct aaagaagaaa ccattcgcca aatcaatatt tacaaccgaa
    13321 cagacactgc ccaggataga ttggcaaact ttgatgtcat tcttttagac agttctggta
    13381 aagaaattga gtaaaaacgt ataacatctc ctaaagatgt gtcagcacaa attacgatta
    13441 accataaaaa agtacgctat gttcggattg agctagaagg ctataatgcc ctcagtcttg
    13501 cagaagttga agttttccgc tttatagcta cgaatgctga aacggcgaca caagtttcta
    13561 agccagttca accaatcagt cagactcctg tgaaagataa aacattgaca attcaacaca
    13621 gtggagctta cattgcccgc tactccataa cttgggaaga agttccagta gataaagatg
    13681 gaaaccaagt tgttcgtagt cattcttggg aaggaaacgg ttgcaaccag actgcaggtt
    13741 ttgtcctcaa cctcccaatc aaagaaaata tgagaaatct gcgagttaag attgagaaaa
    13801 agacgggcct actatggaat agatggcaaa caatctatga aaacagacca attttagctc
    13861 aaccccaccg taaaattacc cattggggta cgacattgaa ttccaaggtg agtgacgatg
    13921 atgtcttgta atctgatggt acaatgacag ttagtttgtc tagtttataa gaaagtacta
    13981 cctgagcttg aatagaactc aggtagctct ctatgaaaga acaaaattaa tactcaatga
    14041 aaatcaaaga gcaaactagg aaactagccg caggttgctc aaagcactgc tttgaggttg
    14101 tagataagac tgacgaagtc agtcacatat ataatccaag gcgacgttga cgtggtttga
    14161 agagattttc gaagagtata aacagaaagg tagagcgcgt gttctaattt gaacacgagt
    14221 agaaaacttt tctaaaaaca aaaacgaaag gatgggtaaa ctgtattcgc tgaactgaat
    14281 acgggcgact ctcctctaaa tcaaaattaa gaaagaaagg aattgaacca ccctaaaagc
    14341 agtgggaaaa agatagttgg tctagcgagc atcgctcact gcgcccaact cctattttcc
    14401 cttcgctttt tgacgggttt ggtatctttc tcaatataaa atataaaata aagaaaggta
    14461 gagcgtgtgt tttgatttga acacgagcgg aaaactcgga aaatagataa tctgactgaa
    14521 aaatcaggat ttctcgtcag gttcctaatt ttcagtcgtt ttcttctcgc tctttgtatc
    14581 ataaattatg tctatccata ttgctgctca gcagggtgaa attgctgata aaattcttct
    14641 tcctggggat cctcttcgtg ctaagtttat tgcggagaat ttccttggtg atgctgtttg
    14701 ttttaacgaa gtgcgtaaca tgtttggtta cactggtact tacaagggtc accgtgtatc
    14761 tgtcatggga actgggatgg gaatgccatc tatttcgatt tatgcgcgtg agttaatcgt
    14821 agactacggt gtgaagaaat tgattcgtgt gggaactgca ggttctttga atgaagaggt
    14881 tcatgttcgt gaattagttt tggcgcaggc ggctgcaacc aactcaaaca tcgttcgtaa
    14941 tgactggcca cagtacgatt ttccacaaat tgctagcttt gatttgcttg ataaagccta
    15001 ccatatcgcc aaaaaacttg gtatgactac tcacgttggg aacgttttgt catctgatgt
    15061 cttttactca aattactttg aaaagaatat cgagcttggt aaatggggag tcaaggctgt
    15121 ggaaatggaa gcagcagctc tttactatct tgctgcccaa taccatgttg atgcgctagc
    15181 tatcatgacc atctctgata gcttggtcaa tccagacgaa gacacaactg cagaagaacg
    15241 tcaaaatacc ttcactgata tgatgaaggt tggtttggaa accttgattg cagaataatt
    15301 atagccaaaa aggaagccct ttatgaattg taggacttcc ttttcttatc cagaaattga
    15361 tctagctctc tctgatttcg aagaatagtg actttatgtg aatattcttg gcaaagtttt
    15421 tggtaatttt ctttttgagt tttgctacgc ccatcccaaa gaatccatct gataaactcc
    15481 cactcaaagc gttcagggca atctgccgcc atactttctc tgacttttcc acggtattta
    15541 agataacgct taaaggctct aaagagacag gtcaatggcg aaaaattgag aaagatgatt
    15601 tggtcagctt cttgcattcg ttcttggtag tagcaccaag aataattacc atcgatgacc
    15661 caagctttat gcttggtgag aaagtttttt atctcggtta acatccattc gcagtcactg
    15721 tcttgccaac caggttgaaa ttggagtgtg tccatgtgca gttttggaat ggagtagtag
    15781 ttagataact tttctgctag agttgactta ccagaaccag aatatccgat aattgcgatt
    15841 ttcattttct accttttcct atttggagac aaaaaaacag cctctatgga ctgtttctta
    15901 tttagcaagt ttagctgaaa gacgagcttt atcgcggctt gctttgtttt tgtgaatcaa
    15961 acctttagtt tctgctttat cgatagctga gctagcagca cggaaaagtt cttcagatgg
    16021 gtttgcttcg aaagctttta tagcagtacg catagctgat ttttgagctg agttcttttc
    16081 gttttgttta acgttcaatt cagcgcgttt gatagctgat ttaatgtttg ccaatgttct
    16141 tacctccata tttactaact ataccattat atatgaaaac ttacgttttg acaagggaaa
    16201 attacttttt taagtaaatt tcatcgattt catggttctt gcttttatga agaatcactt
    16261 ctgcacgatt tctggttggt tcaatataat tttgcagatt tgtgagattg atactggtcc
    16321 agacctgatg ggcaaaggac tccacttccc caatcggcat ctgagtaaaa cgataatagt
    16381 agctatcagg gtcgttttgg gctaggctca gcattttcaa gaaacggtcc agataccaac
    16441 tttcaatatc atccactcca gcatctacat agatggaaaa gtcaaagaag tcagtgatat
    16501 agagacgatc gttttgtgga ttttgaaaga cattaattcc ctcaacaatt acaaaatcag
    16561 cagctttgac actttgtttc ttttcgggta cgatgtcgta aacttcatga gaatagacag
    16621 gaatatctac atcttgtcca tttttgatgc ggtccaagaa gttgagaaga gcttccatat
    16681 catagctttc aggaaatcct ttacgattta aaatcccctg ctcaatcaag gtttgattgg
    16741 gatagagaaa accatcagtt gtaaccaact caaccgtagc atctgtaaac gtacgggaca
    16801 gtaggatttg aagtaggcga ctggttgtgg attttccaac ggcaacactc ccagaaaccc
    16861 caataataaa aggttgagat ttactttcac gttggaggaa aattcctttt gaaaaggcta
    16921 aatcttcctt agttcgcttg taaatctgaa tcagatgagc caaggggaga tagatatctg
    16981 taacgtcttg gagactgatt tggtcattaa aactcttgat agattccaat tcttcttctg
    17041 tcaaaggagg tgttgtcttt cgatgtaaag attgccaagt ctggcggctg attttttcaa
    17101 aatgtaaaaa ttcgttggtc atttgttttc ccctaggtat tttatctatc ataccataaa
    17161 aagctaaaaa aataaagcgg tttcttgaat gttgtaagtc aatgatatat aatataagcg
    17221 atcaatttat tgatgaaata ggagatagat tctactgatt tataagctta taaagggggc
    17281 tttttagttc acaacttata ggagatgtac tatgaaaatc ttaaaacgtt acatattgga
    17341 actctgtttt attttaagtt ttgctttacc ttttataaaa ggagccaatg cagataatgg
    17401 tagatgcttt gtggaaacct attacggttt tacttttttg atggaacatg ctattgtaac
    17461 agctgtcttt atctgttcgt tcttaattgc tgtcttacta aaaaacgatg ggcgaaatgg
    17521 attgcgacag agggttattt cttccgcatg tcactagaag atttgatacg actttggaca
    17581 agtttggaaa tcctgacaca aacgtatcag ttgggctttt atctaaacat tttgttagga
    17641 attttgttga taataaagta ttttaaggtt aagcaataga aataataatc tgcctgatta
    17701 tagatgataa actttttgtt tttatctgga ctgtgatatt tatagttcta aatggtttat
    17761 tatttataag tgttgaaaga gattgaagaa aatggcttcg tgacttgctt tcttcggtct
    17821 ttttcgtttt attatcaatt tgtaaacgat ttacaatttg agtcaaatta tggtaaaata
    17881 gtgtcatgag taaaatgtat tatgcagaaa atcctgacgc tgctcacgac attcatgagt
    17941 tgagagtgga cttgttggga caaaaaatga cttttttgac agatgcgggt gtttttagca
    18001 agaaaatggt tgactttgga agtcaactct tgctcaagtg tctgtatgtc aaccaaggag
    18061 agacagtcct agatgtaggc tgtggttatg gtccattagg tttgtccttg gtcaaggttt
    18121 acggagttca ggcgaccatg gttgatatta acactcgtgc cttggattta gctcggagaa
    18181 atgctgaaaa aaataatgca aaagcgacga ttttccagtc caacatctat gaacaagttg
    18241 aaggacattt tgatcatgtc atttccaatc ctcctatccg tgcgggcaag caagtcgttc
    18301 atgaaatcat tgagaaaagt aaagatttct tggaaactgg tggggatttg acaatcgtca
    18361 tccagaaaaa acaaggggct ccaagtgcta agtccaagat ggaggatgtg tttggtaatt
    18421 gtgaaatcct taaaaaagac aaaggatact atatccttag aagtgtgaaa gaatgagagc
    18481 agttgattta atacaaaaaa aacgagacgg tcaagaactg acttcaagtg aaattgaatg
    18541 gctggtagaa ggctatgtgt caggaactgt tcctgattat cagatgtctg cctttgctat
    18601 ggctgtttat tttaaaggaa tgacgactcg tgaaatttct gatttaacga tgaatatggt
    18661 taagactggg caagagtttg acctgtcagc cattgatggt gtgaaagttg acaagcattc
    18721 tactggtggt gtcggcgata aggtaacctt gattttagct cctcttgttg ctagcttcgg
    18781 tgtgcctgta gcaaaaatga gtggtcgtgg tcttggccat acaggcggaa caattgataa
    18841 attggagtcc attaagggct atcaagtaga acgtagtcaa gaggatttta ttcgtcaggt
    18901 tcaggatatt ggagtatctg tcattgggca atcagaccag ctggtcaaag cagataagct
    18961 tctctatgcc cttcgtgatg tgaccgcaac tgtcgacacg attcctttga ttgcgagttc
    19021 ggtgatgagc aagaaaattg cggcaggggc ggatgctatt ttgctagacg tgactgtcgg
    19081 tgagggtgcc ttcatgaaga cggttgatga ggcgcgtgag ttggctcaaa ctatggtaga
    19141 tcttggtaag gttgttggac ggaagacagt agcagtgatt acggatatga gccagccttt
    19201 gggacgagcg attggaaatc gtctggaaat ccttgaagca ttggagattt tgcaaggtca
    19261 aggacgtcag gatattaccc actttatttg tgaattggct caaattatgc ttggtttggc
    19321 aaatgttaac aaaactgttg aagaagttcg ccaacatctt gaaaatggtc aagcactggc
    19381 taagtttgag gaaatggtgc aagcccaagg tggagacttg gaagacctct atcgtcctgt
    19441 aaatgtagct catgtggtgg aaatccctgc tcaggaaacg ggtgtcattt cagctcttcc
    19501 agctatggac tttggtcttt atgccatgag gctgggtgct ggtcgtgcag ttaagtctga
    19561 tgtcttggac tatgaaacag gaattgtttt tgaaaagaag attggagact ccgttcaaaa
    19621 gggtgaaatt gttgcaaaag tatacacaaa tgaaaaaatt ccacctcaac tagttacaga
    19681 tttccaaaaa tgtgttaaaa taagtgatga agtgaaaaaa atccgtgaaa ttgtagaaat
    19741 catctcctaa atggagggaa aaccgaaatg aaattaaata aatatataga tcatacgctt
    19801 ttaaaacaag atgcaaagaa aaaacaaatt gatagtttgt tgtctgaggc tagagagtat
    19861 gactttgcca gtgtttgcgt taatccgacc tgggttgaac atgctaaaaa aggacttgaa
    19921 ggcacagatg ttaaggtttg cacagtagta ggtttccctt tgggagcaac aacttcagcc
    19981 gtgaaagcat ttgagacaaa agaagctatc caaaatggtg cagatgagat tgatatggtg
    20041 atcaatgttg gagctctcaa atcaggtaat ttagccttgg ttgagtcaga tattcgcgca
    20101 gtagtggaag caagtggtga taagttagtg aaagtcatta ttgaagcttg ccttctgaca
    20161 gaccaagaaa aaattgttgt ttgccaattg gcccaaaaag ctggggctga ctttgttaaa
    20221 acatctactg gcttttcaac tggtggtgct acgatagcag atgttagatt aatgcgtgaa
    20281 acagttggat ctgatatggg agtcaaggct gctggtggag ctcgttctta tgcagatgct
    20341 cttgcctttg tcgaagcagg tgcgacccgt atcggaacgt cagctggggt agctatttta
    20401 aaaggagaat tggcagatgg cgactactga gttgattgaa ctggcaattg aaaccagcaa
    20461 acatgcctat gtcccctatt ctcactttcc tatcggagca gttttagtag ccaaagacgg
    20521 aagtgtttac acgggagtga atatcgaaaa tgctagctat cctttgacca attgcggtga
    20581 gagaacagct gtttttaagg ctatatctga aggccaaaga gaattttcag aattgattgt
    20641 ctatggtcaa actgaaaaac cgatctcgcc atgtggtgct tgtcgccaag taatggtcga
    20701 attttttgaa caagatttaa aagtgacctt agtcgcaaaa gataaatcga cggtcgagat
    20761 gacggtcggg gaattacttc catactcttt tacagactta aactagtctg agtcgctctc
    20821 tgagtggcac ggtccttgtg gccaaccaat ccatacttgc aacatcgttg cacatcttat
    20881 ttaggaggtt cagtaatgaa caagaaacaa tggctaggcc ttggtctagt tgcagtggca
    20941 gcagttggac ttgctgcatg tggtaaccgc tcttctcgta acgcagcttc atcttctgat
    21001 gtgaagacaa aagcagcaat cgtcactgat actggtggtg ttgatgacaa atcattcaac
    21061 caatcagctt gggaaggttt gcaggcttgg ggtaaagaac acaatctttc aaaagataac
    21121 ggtttcactt acttccaatc aacaagtgaa gctgactacg ctaacaactt gcaacaagcg
    21181 gctggaagtt acaacctaat ctttggtgtt ggttttgccc ttcataatgc agttgaagaa
    21241 gcagctaaag aacacactga cttgaactat gtcttgattg atgatgtgat taaagaccaa
    21301 aagaatgttg cgagcgtaac tttcgctgat aatgagtcag gttaccttgc aggtgtggct
    21361 gcagcaaaaa caactaagac aaaacaagtt ggttttgtag gtggtatcga atctgaagtt
    21421 atctctcgtt ttgaagcagg attcaaggct ggtgttgcgt cagtagaccc atctatcaaa
    21481 gtccaagttg actacgctgg ttcatttggt gatgcagcta aaggtaaaac aattgcagcc
    21541 gcacaatacg cagccggtgc agatattgtt taccaagtag ctggtggtac aggtgcaggt
    21601 gtctttgcag aggcaaaatc tctcaacgaa agccgtcctg aaaatgaaaa agtttgggtt
    21661 atcggtgttg atcgtgacca agaagcagaa ggtaaataca cttctaaaga tggcaaagaa
    21721 tcaaactttg ttcttgtatc tactttgaaa caagttggta caactgtaaa agatatttct
    21781 aacaaggcag aaaaaggaga attccctggc ggtcaagtga tcgtttactc attgaaggat
    21841 aaaggggttg acttggcagt aacaaacctt tcagaagaag gtaaaaaagc tgtcgaagat
    21901 gcaaaagcta aaatccttga tggaagcgta aaagttcctg aaaaataatg gatggaagtc
    21961 atttcttagg aagcggccaa gggccgcttt tttaagagtt gagacaaagt cattttgtct
    22021 cagtaaagct tgctactaga caaactagca agttttattg aaataaaata agactctgaa
    22081 aggaagagca catggcacac gaaaatgtca ttgagatgcg tgatattacc aaggtgtttg
    22141 gtggatttgt tgctaacgac aaaatcaact tgcacctacg aaaaggtgaa attcatgcac
    22201 ttttaggaga aaatggggct ggtaagtcca cgctaatgaa catgttagca ggccttcttg
    22261 aaccaactag tggtgaaatc gcggtcaacg gtcaagttgt caatctcgac tccccatcta
    22321 aagcagctag cttgggaatc gggatggttc accagcactt tatgttggtt gaagccttca
    22381 cagtggctga aaacatcatt ttaggtagtg aattgactaa aaatggtgtg ctagatatcg
    22441 ctggagctag caaagaaatc aaggctcttt ctgaacgtta tggcttagct gttgaccctt
    22501 ctgccaaggt agcagatatc tcagttggag cccaacaacg tgtagaaatt ttaaaaacac
    22561 tttatagggg ggctgatatc cttatctttg acgaaccaac ggctgttttg actccatcag
    22621 aaattgatga gttgatggct attatgaaaa atcttgtcaa agaaggaaaa tcaattatct
    22681 tgattaccca caaattggat gaaattcgcg cagtttctga ccgtgttaca gttatccgtc
    22741 gtgggaaatc aattgaaacc gttgaaattg caggggctac caatgctgat ttggcggaaa
    22801 tgatggtagg acgttctgtt tcctttaaaa cagagaagca agcctctaaa ccaaaagaag
    22861 tggttttgtc tatcaaagat ttggtggtca atgaaaaccg tggtgttcca gctgttaaaa
    22921 atctgtcctt ggatgttcgt gctggagaga ttgttggtat tgcggggatt gatggaaatg
    22981 gtcagtctga actgattcaa gccattacag gtcttcgtaa ggttgaatct ggtagcattg
    23041 agctaaaagg agattcaatt gtaggcttgc acccacgtca gattacagaa ctaagtgttg
    23101 ggcacgttcc agaagaccgt caccgtgatg gcttgatttt ggaaatgatg atatctgaaa
    23161 atattgccct tcaaacctac tataaagaac cacatagtaa aaatggaatt ttgaattatt
    23221 caaatattac ttcttatgct aaaaagctga tggaagagtt tgatgttcgc gctgccagtg
    23281 aattagttcc tgcagctgca ctctcaggag gaaatcaaca aaaagcaatt attgctcgtg
    23341 aaattgatcg agatcctgat ctccttatcg ttagccagcc aactcgtggg ttggatgtcg
    23401 gtgccattga gtatatccac aaacgcttga ttgaagagcg tgataatggc aaggctgtcc
    23461 ttgttgtcag ctttgaattg gatgagattt taaacgtctc agaccgtatt gccgttatcc
    23521 acgatggtaa gattcaaggt attgtatcac cagaaacaac caataaacaa ggacttggtg
    23581 tcttgatggc tggtggaaac ttgggaaagg agaagagtga tgtctaaaaa attacaacaa
    23641 atttcggttc ccttgatttc tgtattccta ggaattttac tcggagccat tgtcatgtgg
    23701 atcttcggtt atgatgctat ttggggctac gaagaattgt tctatacagc ctttggcagt
    23761 ctgcgtggga ttggagaaat cttccgtgct atgggtcctc tggtcttgat tggtcttggt
    23821 tttgcggttg ccagtcgagc tggtttcttt aacgtcggac ttcctggtca ggctttggca
    23881 ggttggattc tcagtggttg gtttgccctg tcgcatccag atatgccccg tcccttgatg
    23941 attctagcaa ccatcgtgat tgccttgatt gctggtggga ttgtcggagc gattccaggt
    24001 attcttaggg cctatctagg gacgtcagag gttattgtaa ccatcatgat gaactacatt
    24061 gtcttgtatg tagggaatgc ctttatccat gctttcccta aagacttcat gcaaagtaca
    24121 gattcgacca ttcgtgttgg ggctaatgca acctatcaga caccttggtt ggctgagttg
    24181 actggtaact cacggatgaa tattggtatt ttctttgcca tcattgccgt tgcagttatt
    24241 tggttcatgc tcaagaaaac aactcttggt tttgaaatcc gtgcagttgg tcttaatcca
    24301 catgcttcag aatatgctgg tatttctgcc aagcggacta ttatcctatc tatgattatt
    24361 tcaggtgcct tggcaggtct tggtggatct gttgaaggtt tgggaacctt ccagaacgtc
    24421 tatgttcaag gttcgtcatt agctatcgga tttaacggaa tggcggttag tttgcttgcg
    24481 gccaactcac caattggtat actctttgca gccttcctat ttggcgttct ccaagttggg
    24541 gctcctggta tgaatgcggc gcaggtacca tctgagcttg tcagcattgt aacagcgtct
    24601 attatcttct ttgtcagtgt tcattacctt atcgaacgct ttgtcaaacc gaaaaaacaa
    24661 gttaaaggag gtaagtaaag atgtctatta taaccttgct ccccctcttg gtgtcttcta
    24721 tgctgattta ctcagcacct ctcatcttta caagtatcgg tggtgttttc tctgaacgtg
    24781 gtggtgtggt aaacgttggc cttgaaggaa ttatggttat gggtgccttt tctggagttg
    24841 tctttaacct tgaatttgca gaacaatttg gagcagcaac tccatggcta tccttgcttg
    24901 tagcaggatt ggttggtagt gttttctcta tcatccacgc agcagcgacg gttcatttcc
    24961 gtgcagacca tgttgtcagc ggtacggtat tgaacttgat ggcgcctgcc ttggctgttt
    25021 tcttagttaa agttctttat aacaaaggac aaaccgacaa cctaagtcaa acttttggac
    25081 gctttgattt cccagtcttg gcaaatatcc cagtgattgg tgatatcttc ttcaagtcaa
    25141 ctagtctact tggttatctg gcgattgcct tctcattcct tgcttggttt attctcttta
    25201 agactcaatt tggtcttcgt ctccgctctg tcggtgaaca tcctcaagca gcggatacct
    25261 tgggaatcaa cgtctacaag atgagatatt tagggattat tatttcaggt tttctaggtg
    25321 gaattggcgg agcgatttat gcgcaatcaa tctcagttaa cttctcagtg acaactattg
    25381 ttggacctgg atttatcgcc cttgctgcga tgatctttgg gaaatggaat ccaatcggtg
    25441 ctatgctttc tagtctcttc tttggacttt cacaaagttt ggctgttatc ggttctcaat
    25501 tgccgttcct acaaggagtg ccagcggttt atcttcaaat tgcaccttat gttttgacaa
    25561 ttcttgtctt agcagccttc tttggaaaag cagtcgcacc aaaagcagat ggtatcaact
    25621 acatcaaatc aaaataagca tacaaaaaaa cgtcagtcca atgactgaac tgccccccaa
    25681 aagttagaca ga
//
LOCUS       DAVLZS010000028        25500 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLZS010000028 DAVLZS010000000
VERSION     DAVLZS010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.028"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(513..1307)
                     /locus_tag="VYO88_001255"
     CDS             complement(513..1307)
                     /locus_tag="VYO88_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719352.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            complement(1307..2314)
                     /locus_tag="VYO88_001256"
     CDS             complement(1307..2314)
                     /locus_tag="VYO88_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1719353.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(2314..3321)
                     /locus_tag="VYO88_001257"
     CDS             complement(2314..3321)
                     /locus_tag="VYO88_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1719354.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLRISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(3311..4336)
                     /locus_tag="VYO88_001258"
     CDS             complement(3311..4336)
                     /locus_tag="VYO88_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1719355.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLLDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(4729..4946)
                     /locus_tag="VYO88_001259"
                     /pseudo
     CDS             complement(4729..4946)
                     /locus_tag="VYO88_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(5237..5470)
                     /locus_tag="VYO88_001260"
     CDS             complement(5237..5470)
                     /locus_tag="VYO88_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEV1719356.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(5684..7315)
                     /gene="rlmD"
                     /locus_tag="VYO88_001261"
     CDS             complement(5684..7315)
                     /gene="rlmD"
                     /locus_tag="VYO88_001261"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1719357.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(7389..8363)
                     /locus_tag="VYO88_001262"
     CDS             complement(7389..8363)
                     /locus_tag="VYO88_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV1719358.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVVAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(8437..9051)
                     /gene="pmp23"
                     /locus_tag="VYO88_001263"
     CDS             complement(8437..9051)
                     /gene="pmp23"
                     /locus_tag="VYO88_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1719359.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(9051..10025)
                     /locus_tag="VYO88_001264"
     CDS             complement(9051..10025)
                     /locus_tag="VYO88_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1719360.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(10033..11289)
                     /locus_tag="VYO88_001265"
     CDS             complement(10033..11289)
                     /locus_tag="VYO88_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1719361.1"
                     /translation="MIFDKHDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAVAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(11351..11782)
                     /locus_tag="VYO88_001266"
     CDS             complement(11351..11782)
                     /locus_tag="VYO88_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719362.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(11784..12386)
                     /locus_tag="VYO88_001267"
     CDS             complement(11784..12386)
                     /locus_tag="VYO88_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1719363.1"
                     /translation="MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(12370..13209)
                     /gene="prmC"
                     /locus_tag="VYO88_001268"
     CDS             complement(12370..13209)
                     /gene="prmC"
                     /locus_tag="VYO88_001268"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1719364.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADISQEALDLARENAKNQNLQ
                     IFLKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDATDYLKDSGKIYLEIGYKQGQCVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(13209..14288)
                     /gene="prfA"
                     /locus_tag="VYO88_001269"
     CDS             complement(13209..14288)
                     /gene="prfA"
                     /locus_tag="VYO88_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1719365.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(14285..14875)
                     /locus_tag="VYO88_001270"
     CDS             complement(14285..14875)
                     /locus_tag="VYO88_001270"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1719366.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GIGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKTYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            14999..15181
                     /locus_tag="VYO88_001271"
     CDS             14999..15181
                     /locus_tag="VYO88_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1719367.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAIVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            15319..16692
                     /gene="mnmE"
                     /locus_tag="VYO88_001272"
     CDS             15319..16692
                     /gene="mnmE"
                     /locus_tag="VYO88_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1719368.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     SQVASHTLNYGHIVDPLTGKVMDEVMIGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQETNRII
                     LLNKTDLPETIETSELPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDVAPDELITQLF
                     SQFCLGK"
     gene            complement(16739..17674)
                     /gene="dapA"
                     /locus_tag="VYO88_001273"
     CDS             complement(16739..17674)
                     /gene="dapA"
                     /locus_tag="VYO88_001273"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1719369.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(17730..18806)
                     /locus_tag="VYO88_001274"
     CDS             complement(17730..18806)
                     /locus_tag="VYO88_001274"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1719370.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKT
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGAVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGAKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(19148..19220)
                     /locus_tag="VYO88_001275"
     tRNA            complement(19148..19220)
                     /locus_tag="VYO88_001275"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19185..19187),aa:Thr,seq:ggt)
     gene            complement(19320..19829)
                     /locus_tag="VYO88_001276"
     CDS             complement(19320..19829)
                     /locus_tag="VYO88_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1719371.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(19827..19923)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            19952..20383
                     /locus_tag="VYO88_001277"
     CDS             19952..20383
                     /locus_tag="VYO88_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1719372.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            20465..20842
                     /gene="mscL"
                     /locus_tag="VYO88_001278"
     CDS             20465..20842
                     /gene="mscL"
                     /locus_tag="VYO88_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1719373.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(20884..21978)
                     /gene="hemH"
                     /locus_tag="VYO88_001279"
     CDS             complement(20884..21978)
                     /gene="hemH"
                     /locus_tag="VYO88_001279"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1719374.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVTLVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            22133..23353
                     /gene="pepT"
                     /locus_tag="VYO88_001280"
     CDS             22133..23353
                     /gene="pepT"
                     /locus_tag="VYO88_001280"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1719375.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVRSL"
     gene            complement(23396..24025)
                     /locus_tag="VYO88_001281"
     CDS             complement(23396..24025)
                     /locus_tag="VYO88_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719376.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTTGNQEKPVE"
     gene            23990..24211
                     /locus_tag="VYO88_001282"
     CDS             23990..24211
                     /locus_tag="VYO88_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719377.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(24482..25494)
                     /locus_tag="VYO88_001283"
                     /pseudo
     CDS             complement(24482..25494)
                     /locus_tag="VYO88_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         7521 a         5138 c         4536 g         8305 t
ORIGIN      
        1 ataaaatttt caaaaactct ataattttta tcatctatat cttcgtagta acctaagata
       61 ccattgtcaa tatttgtagc actaattcta ggagtttttc catcgagtaa atatcttttt
      121 ggaatagatg agcctgttgg tacttgactc gatttcccct ttttttcggt aataaatatt
      181 tctttttatt ttgttgtctg atatttttcc tacctgtcct ttgtaggatg agtattttct
      241 agattttctt gaataacttt ttacttgaag ttttagcttt tgaactagtc gttgtacttt
      301 ctttttgttt attatcagtc ctgatctttt taatattgct gttattctct atatcctatt
      361 tttcattcat gatattcttt tacgaatttt atcttaaatt ctgtgctgta tttgccatta
      421 aaaaactgac ctcctttagt tagttttttg gcctaacttt tgagggtcag ttcaaaagtt
      481 gcgactttta aatgaattcc aatattcaat tattaagagt taacatggtg cttgccaata
      541 ggaatcatta gaggcgaatt ggaaataggg tcacgtataa tttttgcttc aagattaaag
      601 atatctttaa ctagtttatc atttagtata tcttcaggct ttccctctgc aacaagttta
      661 ccttctttaa ttgcaaatag gtaatcagcg tatcttgctg ttagatttat atcgtgcaaa
      721 atcatgcaaa tggttgtctt atatttttgg tttagatcag tcaagaggtc taatagttct
      781 atttgatatg agatatccaa gtaagtagtt ggctcatcta aaagtaggat acttgtatct
      841 tgggctaggg ctagagctat ccatactctt tgcctttgac ccccagaaag ttcttcaact
      901 aggttatttg ctagatcttc aacattggcc ttaaccattg atctgtttat tatttcaagg
      961 tcatcttttc caagactctt aaaaggcttt ctgtagggga aacgaccacg gcttacaaga
     1021 tcagctactg ttattgattc agggattatt ggagattgag gtaatatagc tatgtgtttt
     1081 gctaaatctt tttctttata agaattaatt gatttattat caagcaatac ttctccctct
     1141 aatggcttta taagtcgaga caaggtttta atgagtgttg atttcccaca accatttgac
     1201 ccaataataa ctgatatttt ttcttcaggt atttttatat ttatattttc caagattatt
     1261 ttttcatcat aaccgcaggt aagattattt gaccacagac ctttcattat atattcctcc
     1321 tgttcatttt tattagtaag tatattaagt atggtgaacc taacaagcca gttacaacac
     1381 ctactggata cctagctggt aaaatatttt gagagaatat gtctgataac aaaactagta
     1441 aaattccaac caatccagct aatattgggc ttcttttctt gccaatattt aaggctatgg
     1501 gaccagctaa aaaagatata caagctattg gtcctgtaat tgaagtagaa aaagcagtta
     1561 aagatacagc gcaaaaaatt aaaacaagcc ttgaaagctc gggatttgct ccaagtccga
     1621 ttgctatttc ttcaccaagt tcaataattt ctagtctttt attaaaaaat aaaactaata
     1681 tagtagcaat aatacttact attagaacaa gaggtatgtc atctaacttt gtaaaagata
     1741 aagagccact gagccatctc ataacttctt gtaattcata tcttgctact ttcaacaata
     1801 aaaatgaggt gcctgctctt gtgacagctt gaaaaccaat acctaatatt atcagtcttg
     1861 ctgctgaaaa accatctttt ttagctagta aaaataatat taaagatgat gttagtccac
     1921 aagttattga aataattcca gtagttaaac tatttgtttt taataccaat atgcaaaaga
     1981 ccgctgcaat agatgaagaa cttgtgacac cgattatatc aggacttgca agaggatttc
     2041 ttaacatagt ttgaaagata aatcctgcca atccaaaaga ccagccagct ataattcctg
     2101 ctaataattt tggtaatcta atttccataa tcgaaaaact agctccagga acagtttcac
     2161 tatttaagac tttaatcaaa gttgaaaaag aataactttc atctccgata agtaaaatga
     2221 aaaatgatag actgattatt attaataaaa atagtgagga aaatagtgtt attctatttt
     2281 ttcttttttg aatacctata attaaatttt gcattagtta ttaacccctc tatttttcat
     2341 agttacataa ataagtactg gacccccgat tattgcagta attatcccta cttcaatttc
     2401 acctggttta cctaacatac ggccgattat atcacatata agcaagagct ctgcacctat
     2461 aaaagatgaa gaaatggtca ttgtgcgtat atctttgctt ataaataagc cacaaaagtg
     2521 aggaactata agacctacga agccaatagg tccaccaatt gcagtaatac ttgaacataa
     2581 aagcacactt gcaattattg caagtgatct tatcctatta acattaactc caagaccaac
     2641 agccatttca tcacccatag ctaaagcgtt taaatctgat gaaataaata tagctatcaa
     2701 gtgacctaaa attataaaag gtagtagtgt agatatagaa gataatgtag ctgctccaag
     2761 gctacctatt tgccaaaatc taaatttgtc taagacgtta ttattcggta aaattaaaaa
     2821 acttacaaaa ctgcttaaag ccatactaac acaagttcct gataaggcaa gttttatagg
     2881 ggtaaggcct gcttttccgc ttacagcaat cgcgtataca aaaattgcac ttactaagcc
     2941 accaatgatt gcaaaactta tatggcttat gcttgatgaa attcttaaaa aagaaagacc
     3001 aattactaca ctaagacttg ctcctgtgtt tataccgagt atacctggat cagctattgg
     3061 gtttctagta actgattgca tcaatacacc gcttatggca agactagaac ctgctaaaat
     3121 tgcaaaaata gttctaggta ttcttttata tataattgat ttaataaaat catcatttgt
     3181 attgcccatt ccaaaagctg ctaaaaaatc tctgatatta atttcttttg ttccaagctt
     3241 taatgacaaa aatattgtaa taagaagacc taggcagatt acaaaaatta tgcctaggtt
     3301 tatttgtttt ttatttcgca tttttgcatg catttcctaa aagatttagg tattcttcaa
     3361 tagtatagtt tattgaaagt ggtgttggag tgcatgaggc tgctaacggt gtattatctg
     3421 gaattacagc aacggcacca tttttaattg catttatttt acctaaaaga ggatcttttt
     3481 gtaaagcttc aagagtttta tcatcaccat aagttatgat tacatcagca tcatttatct
     3541 tatttgcttc ttctgcagaa atttcctttg caaaactatc ttcactctca aattctttta
     3601 atgattcagg gaaaactaga cctaaatctg ttaaataatt tgctcttgga tctttgctag
     3661 tataaatcca gaattttgat gtatctgcag cattaatcat agtaaataat actttttttc
     3721 ctttgatttt tcctttgatt tctggatgtt tttctaattc tttggatata cgagcttcag
     3781 tatttttgat taactcatca ccttcttttt ccatacctaa ggcttttgaa tcaattttaa
     3841 tcatatctct ccataaagtt tgccaaggtt tagatttgta tgctgctaca ggagcaattt
     3901 ttgatagagt gtcataatct tctttagtta taccagaata acctgctaag ataacatctg
     3961 gtttagaatt tgatattgct tcaaagttaa gtccatccaa atcgtcaagt aggttagctt
     4021 taccatttag ttctttgatt ttttcttctg tccatggtaa aactccttta tcagcactta
     4081 caccgtaatt tgcttttgaa aatccaacag gaactattcc taaagctaat gctacatcat
     4141 gatttcccca agcaatagtt gcaactcttt caggtttttt atctaatata gtttgaccga
     4201 aagcatgatc taaaactatt ttatcaggcg catgctcttt agaagtattt tcttcatttt
     4261 taacagaatt agaagaacaa gcgctaaaaa ctatacacat agctaaaata gctattagaa
     4321 aaaatttgtt tttcataaaa actccttaaa catatttcaa gtctattgta tcgataataa
     4381 ttatcattgt caatagatac agttacaaat ttaataatat aattttttca aaaaaggatc
     4441 tagtttttat ttttagttaa attatgtcta tatttttcat taactcatca ataaaaattt
     4501 gtttgctaat atctctttct tctgattttg tttcaaggat tattgctaca tcattcatat
     4561 ttttaggtaa ataccaacca tctggcttat ctgaatatcc cttgaagcct aattgattaa
     4621 aagtagttat ttgaccagta ccttgattga tgttttcttc aacttcatta aagcctatac
     4681 ttctcttgca taatccctaa cttgatcttc tgtccttaaa gtcattttct attcctcgtc
     4741 actaaaatta tcttcaaaac taataatatc attaggagtg caagataaag ccttacatat
     4801 tctttctaaa ttcttaaatg taattggttt atcctttccc atttgtgcca taacatttgt
     4861 tgtaagtcct gccatagtta ttacatctgt tttctttagt ctttttttgc taactgtatc
     4921 cataatggtt tatagttaag tgccataata tccctctttt tttcttcatt aaatttattt
     4981 aattatagca taaatattga tttcattcaa tcttacattg atttagtgat ttgttttaga
     5041 gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg ggacctctta
     5101 tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt ttttaatttc
     5161 tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt aaagaatctt
     5221 taaattcatt ggtatgctaa ttacaatatc cattattaaa atggatacta taagcagcac
     5281 accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc cttatattta
     5341 cataactatt tgcctctata actattatga cacgaaacca acaagcaagt tcaagcacct
     5401 ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa acctctttat
     5461 cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt ttgttgcctt
     5521 tatcaatcat ttcaacgctc ctttaaatat aaaaatgatc ctatcaatct ttatattgag
     5581 cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat accaagtagg
     5641 aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc attttgaagt
     5701 gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga ataatttgtt
     5761 tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc ttttttatct
     5821 gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat tctttgattt
     5881 gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc tcaatttcaa
     5941 cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg acgtgatgcg
     6001 tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaac tcttggtata
     6061 gtttaatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg cgatcggctc
     6121 ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga ggatcaacca
     6181 agataacggt tggttgaata ccttccttga gccatttctt catggcattt tcagccgtgt
     6241 cacagacata gtgggcatta gtaatcttgt tcaaagaagc attcttctgg ctattctcta
     6301 ctgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg actgataaac
     6361 caatggttcc aataccagaa taggcatcaa taatcacatc atcttttttt aactctgcaa
     6421 agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg taaaaggctg
     6481 ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct tgaccataaa
     6541 gagtgcgcca ctccttacca aaaatcgcat tggtattctg gtcgttgata ttttgcatga
     6601 cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca acacgaaaaa
     6661 cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga ccacgacgca
     6721 ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt aaatcaaaac
     6781 gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc tggataaaga
     6841 aatcttcaag gggcatgagg tcgtgcgaat tcttacggaa aaatcctgtt tccaagacac
     6901 cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga tgttccatac
     6961 caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga ctgtccttga
     7021 cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa tccgcgattc
     7081 ctgaacgcag gtaagccaaa tctagatctt gattacggtg tggtgactgg acaaggtatt
     7141 tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg agaatttttt
     7201 cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca actcctgccc
     7261 cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt aacattcttt
     7321 tctctttcta ttggccgaca aaaaagacgg caacgttacg gttaccatcc attataccat
     7381 gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca gagggagctt
     7441 aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt gatattttta
     7501 aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt tttagtgaaa
     7561 tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat gatgatattg
     7621 atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc ttcaacaatc
     7681 ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc gagtcctgac
     7741 ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt gtccttgttt
     7801 tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt attggcttgc
     7861 ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc actctcacct
     7921 gtaactggaa taggggctac tacagtgatt ttggcatgtt ccatacccag cgttactgct
     7981 gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc aatcttgacc
     8041 tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa ctgtaagcta
     8101 gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt cttgagttct
     8161 ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt ttggtcttca
     8221 gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat aactttttga
     8281 acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac cgcagcactg
     8341 gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag agtaatatat
     8401 ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg aaaagagagt
     8461 gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat agtttcctcc
     8521 atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac tataagtctt
     8581 tccagtccta ttaccaagca agggggcaac agtctcacga gagtactgtt tggctagagc
     8641 caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc caaaattata
     8701 ggcttgaaca gctgtccaga tatctacccc cttcttctgc gccagataga gattgcctgt
     8761 cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt tggttgaacc
     8821 acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt cagtataaat
     8881 catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaaga tttctcgcac
     8941 catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag ctttatagcc
     9001 agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca ttatttactt
     9061 tggatatcct cgatattttt gattaagata gagtaggttc cattttcgtt ttggataaac
     9121 tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat tccatttgat
     9181 aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat ttcatcaaat
     9241 tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg agccgtcaga
     9301 ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct ttcttctagg
     9361 ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt gttaaaagat
     9421 tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg agaaatctta
     9481 ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt gtacttgatt
     9541 cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc ctcgtcagca
     9601 cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc aacttctcct
     9661 ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg ttctacacct
     9721 tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga aatgctaaac
     9781 tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc tgtaatatga
     9841 ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga atacacatgt
     9901 tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa cttatctgct
     9961 aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt aatataaatg
    10021 tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt tgactgcact
    10081 tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa tgatgagttc
    10141 agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagcta ctgctccgat
    10201 acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat ttttatttag
    10261 ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta caaccttagt
    10321 cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga aatcagggtc
    10381 ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag catattcctt
    10441 gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa catgctctaa
    10501 aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa gttcttcgtc
    10561 attagtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg ttgttgttgt
    10621 gatatgagcg tatggaactg ggcttggatg aaggccagcc gcaaccaagc cagcgatatg
    10681 ggccatgtcc accatgagct tcgcaccgac agcatctgcg atttcacgga attttgaaaa
    10741 atcgataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt ttacttcttg
    10801 ggcttgtttc aagatagcat caaagtctaa gagttccgtt ttaggatcaa cactataaga
    10861 aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca aatgaccacc
    10921 tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca tgtaagccgc
    10981 acagttagct tggcttcctg aatgtggttg aacattggca aatttagcac cgaaaatttc
    11041 ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc caccataata
    11101 acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt gagctgccat
    11161 aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt gttggcgttc
    11221 ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat catgtttgtc
    11281 aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat tttacaataa
    11341 gaaaatcaaa ctaacagatg cgaataaacc gtttctgcat tttatcacaa gtatagccaa
    11401 ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag cggataaacc
    11461 cataaccaca tctttttgct tcttcttcca acccttgtag taaactttta ccaatacctt
    11521 gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct ttggaataga
    11581 gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct gcatcctcat
    11641 agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta gccgtttcct
    11701 ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct ttcacatctg
    11761 tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg caaccgagca
    11821 agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc tccagacaaa
    11881 tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc cagaacctct
    11941 tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc tgagatattg
    12001 gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat agggtgactg
    12061 ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac tcggtcattg
    12121 gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt ttgtagataa
    12181 gctggctgat tctttgaaaa gtgcaagatg tcctcgaaag aggcgatatt gagattgagt
    12241 gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt ttcatctaag
    12301 gccttggaaa aaagaccata aacagtctct gtaggtagaa cgacagctcc acccttttcc
    12361 aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac caaattggtc
    12421 tttgagtgtt cgaactcttt tttcaggaag atgttttcta aaaagttcgg gaacacattg
    12481 accttgcttg tatccaattt caaggtaaat cttaccacta tctttaagat agtctgttgc
    12541 atcttccgca attctacggt aaatagctag gccatcctcg tctgcaaaga gagctagatg
    12601 aggctccgaa tacaagacat tcaagcctac ctctgactca tcttcacgag agatataggg
    12661 tggattggaa acaattatat catatttttc agaaatttct gtaaaacagt cagatttttt
    12721 taaaaatatt tgaagatttt gatttttagc attttctcta gctaaatcta aggcctcttg
    12781 agaaatatct gctgctgtca ctgaccaatc tggtctattt tttgctagag cgagagcaat
    12841 agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat tttcagttag
    12901 aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt catccacctt
    12961 taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct tgtgagctgc
    13021 tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca cctcctgctg
    13081 gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga caaaagagag
    13141 gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa ataattgagc
    13201 taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag caccaaggca
    13261 tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag ggtcaagccg
    13321 atacggtggt ctgtgacacg gttttgaggg aagttataag ttcggatccg ttctgaacgg
    13381 tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc aatctgagca
    13441 aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcacggtt cttctgctgg
    13501 gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat acgaacggca
    13561 gtcgcaacct tattgacgtt ctgtccacca gcacctgatg cgtggtaaat atcaacacga
    13621 agatcttttg gatcgatatc gtattctact tcttcgactt caggcatgac aagaactgtg
    13681 gcagttgagg tatgaacacg accttggctt tctgtcacgg ggacacgctg cacacggtgg
    13741 gcacctgatt cgtacttaag cttagagtat acagactgac ctgaaaccat agcaaccact
    13801 tctttaaacc caccgacacc attcatagag gcttccatga cttcaaagcg ccagccttgg
    13861 gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc cgcttcgtct
    13921 ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg atcctttgga
    13981 aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc atctttgagt
    14041 tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat catctcttcg
    14101 gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac ggtatcacga
    14161 ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac gacatcaggg
    14221 tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag ttgatcatag
    14281 atgttcattt ttcttcattc tccttattga tttcaggcgc aaaataatgt ttacggcaaa
    14341 ccgagatata ggtttcatta ccaccaatct gaatctgctc accatcatag accggcagtc
    14401 catcctgtgt tcgcaaaacc atagtcgcct ttttcttaca atactggcag atggtcttga
    14461 tttcgtcaat cttatctgct aaaagcaaga gatacttgga accttcgaac agttcattgc
    14521 gaaagtcatt tttcaaacca aaagccatga caggtatgtc taactcatca acaacacgag
    14581 ctaggtcgta aacatggtga cgtttgagaa actgagcctc atcaaccaat acacagtaag
    14641 ttttttctgg taggtctcgg atatagccaa agatatccgt cgtctcctca atcgcaagag
    14701 cagggcgttt cataccgatt cgactcgaca catagccaat accgtcacgc gtatccagag
    14761 ccgaggtcat aatcacaaca ccttttcctt gctcctcata gttataggcc accttgagaa
    14821 tctcaatcgt cttaccagag ttcatggtcc cataacgata atacaactgt gccatgtttc
    14881 ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat tttctgaagc
    14941 tttaaacggc aaaatgtggt aaaatagaag aaatcaaaaa ctagtggagg aagctattat
    15001 gccatttgta cgcatcgatt tatttgaagg acgcacgctc gagcaaaaga aagctcttgc
    15061 taaggaagta acggaagcta ttgtccgtaa tactggagcc ccccaatctg ctgtccatgt
    15121 catcatcaac gacatgccag aaggaactta cttcccacaa ggggaaatgc gtaccaaata
    15181 agctagctta agcagaattg cttaggcttt ttcaatctcc aagtaacatc cattgaagaa
    15241 atagcctaaa tttgttacaa tttgaaagga tacttggaaa aatttccaag aaaagagcta
    15301 tttattaaag gaaacattat gattacacgt gaatttgata ccatcgctgc tatctctact
    15361 ccactaggtg aaggggctat tggtattgtc cgcctgagcg gaacagacag ttttgctatt
    15421 gcgcaaaaga ttttcaaagg aaaagacttg agtcaggttg ctagccatac acttaactac
    15481 ggtcacatcg ttgaccctct gactggtaaa gtcatggacg aggtcatgat tggggctatg
    15541 aaatctccaa aaaccttcac tcgtgaagat attatcgaga ttaacaccca cggtgggatt
    15601 gcggtgacta atgaaattct ccagctagct atccgtgaag gagctcgatt ggctgaacct
    15661 ggtgaattta ctaaacgtgc cttcctaaat ggacgtgttg acttgactca ggctgaggca
    15721 gtaatggata tcatccgtgc taagacagat aaagccatga acattgcggt caaacaacta
    15781 gatggttctc tttctgacct cattaacaat acccgtcaag aaatcctcaa tacacttgcc
    15841 caagtcgaag ttaatatcga ctatcctgag tatgatgatg ttgaggaagc gactactgct
    15901 gttgtccgcg agaaaactat ggaatttgaa caattgctaa ccaatctcct taggacagcc
    15961 cgtcgcggta aaatccttcg tgaaggaatt tccactgcca tcatcggacg tcccaacgtt
    16021 gggaaatcta gcctcctcaa caatctcttg cgtgaggaca aggctatcgt tacagatatt
    16081 gctggtacca cacgtgatgt catcgaagaa tacgtcaaca tcaacggtgt tcccctaaaa
    16141 ttgattgaca cagctggtat tcgtgaaacg gatgatatcg ttgaacaaat tggagttgag
    16201 cgttcgaaaa aagctcttaa ggaagctgac ctagttctgc tagtactaaa cgctagtgaa
    16261 ccactaaccg cccaagatcg ccaactccta gaaatcagtc aggagactaa tcgcattatt
    16321 cttcttaaca aaactgacct gcctgaaacg attgaaactt cggaactacc tgaagatgtc
    16381 atccgcattt cagttcttaa aaatcaaaac atcgataaaa tcgaagagag aatcaacaac
    16441 ctcttctttg aaaatgctgg tttggttgag caagatgcta cctacttgtc aaacgcccgt
    16501 cacatttcct tgattgaaaa ggccgttgaa agcctacaag ctgttaacca aggtcttgaa
    16561 ctagggatgc cagttgactt gcttcaagtt gacttgaccc gtacttggga aattctagga
    16621 gaaatcactg gagatgttgc tccagatgaa ctcatcaccc aactctttag ccaattctgt
    16681 ttaggaaaat aagaaaaatc catgatcctt cattcggtca tggattttat tgtctttatt
    16741 agtaatctgg tcttaagacc cctgttacag ttgccttggt cgcttcgtag tcgccatcta
    16801 cgacaacctt gataatgcgt ttggcatctt cttctggtgc tggaacaaga ggtagacgag
    16861 tgggtccagc ttcaaatccc atatagttaa gaactgcctt aactggagca ggacttggat
    16921 aagagaagag ggcattaacc ttaggaatga atttacgttg aatagctgcg gctttcttca
    16981 tatcgctttc tgcaatggca gtaaacatct cgtgcatttc atccccattt gtatgagagg
    17041 caacagaaat aaccccatcc gccccaaggt tcatggcatg gaaagcatct ccatcctcac
    17101 ctgtataaat caagaactct tcaggcttgt gctcaatcaa gtaagccata ttagccaagc
    17161 tagtacattc tttgacaccg ataatatttg gatggtcagc caaacgaagc atggtttctg
    17221 gagtcaattc gacaactaca cgccctggaa tgttatagat aataattggt aggtcagaag
    17281 catctgcaat agccttaaag tgctgataca tcccttcttg agaaggtttg ttgtagtaag
    17341 gaacaatagc aagcccagct gcgaaaccac caaattccgc tacttctttg acaaactcaa
    17401 tagagtcacg cgtatcatta gtacctacac ccgcaatcaa aggaacgcgt ccattgacaa
    17461 ccttttgtac agccgcaaac aactccaact cctcatcgtg ggtcaaagtt ggactctcag
    17521 cagtcgttcc tgcgagaaga attccatccg tatgatgggc caataaatgc tcaatcaagg
    17581 ctggaatagc atcaaagtta atggaaccat cctcatggaa gggggtaata aaggctgtaa
    17641 tgattttaca ttcttttaaa tcttgataag acacgaaaac acctctctat ttcaaagaag
    17701 gagttcatct gaactcctaa acgatatgac tattttaatt caaatttcaa ttcggctgtt
    17761 ggacgaacca atccacgttc atgaagagtt tcagcaatct gaactgagtt ccaagcagca
    17821 cctttgagaa ggttatctga aacaacccac atgtgaattc ctttttctgc atccaagtct
    17881 ttacggatac gaccaacaaa ggtatcacgc gaaccaactg cattgatagc ttgaggatag
    17941 atttgatgag ctacatcatc ttcaagaaca gcacctggga aggctgcgat agctgctttt
    18001 acttcttcga ttggagccac ttcttttgtt tcgatataaa cagactcaga gtgagctgac
    18061 aagactggaa tacgcacaca tgttgcagat actgcaatgc tatcatcttc cataattttc
    18121 ttagtttcct tggtcatctt catctcttcg taagtgtaat cattgtcagt gaagacatcg
    18181 atttgtggaa gagcattgaa ggcgatagga taatgtttct tgtcaccgcc tgaaggtaag
    18241 atttccgcat gcaaatcacg tggtttcgct ccatcattca agacctcacg aagttcacgt
    18301 tgcgtctcaa gaattgctcc cataccagca cctgaaacgg cttgataagt tgaaacaatg
    18361 atacggtcca agccccattt ttggcgaact ggctcaagag ctaccatcat ttggattgtt
    18421 gaacagttag ggcaagcaat aatcccgttg tgggcatcaa gtgcgtgagc attgacctct
    18481 ggaacaacca aaggaacgtc tggattttga cggaagtaag atgtattatc tactactact
    18541 gcgccagctt taactgcgta tggtgcatac ttagctgatg tcgaaccacc tgctgaaaaa
    18601 agagcaatat caactccttc aaaagctgtt tcagtcgttt cttcaatcgt aatatcttga
    18661 tctttaaatt tcaatgtctt gcccgctgaa cgagcagaag caaggtaacg aattttatca
    18721 attggaagtg ttgattcttc caacattttt atcatctgag ctccgacagc acctgtcgcg
    18781 ccgactacag caactgtata tcccataaat aacctctttc ggaattttct aaaaatttct
    18841 ataatagaag tattatacta ctttttccat gaattgcaaa gctttttcat cattttttgg
    18901 aaaataaaaa tcccagtcgc tagactaggg actaagaggc atcttcatgt gatgagcagg
    18961 ttcacacaac tcatcaaggt ccgctcctgc gttatgacct ccttatgctc aatagtagtc
    19021 cgaagactac ctatcgactc atcgcatatt ctatattact agagatactt gattttgtca
    19081 ataagaaatt ttttcgatcg agtataacaa aaaactctcg tattcaagag tttccctata
    19141 catatcatgc taattgccgg gattgaaccg gcgacctcat ccttaccatg gatgcgctct
    19201 gccaactgag ctaaatcagc ttacttaaga agtatactat attcagaaaa acttgtcaag
    19261 tttccttaga aattttccat aggaaaaagc caggtaagaa ctacctagct tatcttcttc
    19321 tatttactta aatcaattcg acgaccaatt ttaccaataa taatcgctcc aataatcaat
    19381 gaagcaaatt caccgattcc tgttgtaaac caagtaagga agaatggtaa ttctgctaca
    19441 atatttaact ctgcagcgat agtaaacatg gaaattgaaa agaggattga aaagaagaaa
    19501 tgatcttttc gaatcaatcc gttaaagagg taatccttgc tatattttgc aaaaagccaa
    19561 acacctaaac tgaggaatac taaggttgaa ccaccaccaa caaagacatc tagcagtccg
    19621 aagctaaaga aattagcaat catacaaccg atggtaactc cgatgatgta cttaggattg
    19681 taaaaagcca taaagttcat catttctgaa atacgaaact gataagcacc atagctgatg
    19741 gcatttaggg gcggtgtgac agtcaaaacg acgtagatag cagcgacgat tgcaatatct
    19801 gcaacatcac gaatagttaa ttttttcatc ttttctcctt tggcggttat ccgcgtgtaa
    19861 tatgcttggt gaaagaagct aagcaccaag ggttgattca ttcaacctta ctagtatagc
    19921 acaatagcct gctttatgct atacttaaag catgaaaaaa cctattcaaa aattttttaa
    19981 caatgaaatc ttagcctatc tcttttttgg ccttgcgaca actctagttt cgattctctc
    20041 acgactagtc atttatcaac taagtcatca ggaactcctt gctacggcct tggcaaatat
    20101 tatcggtatc ttatttgcct ttatcacaaa tgatacgatt gtatttaagc aaaaaaagaa
    20161 aaatagactt atccgtttag tgaaattttc tcttgcccgc ctttctactt ttctgttaga
    20221 cttgttttta acttttctct ttgtaaccca atttcctcac atcatagggc aattcgtaac
    20281 tgaaaacatt gataagataa atgctattga aacaataatt gcacaaatat tcattattat
    20341 catcaattat atcttgagca aggtctatat ttttagaaaa taatgctcca tttatgagcc
    20401 ttttaattgc cttctataat gatttaggat acaatgaaac acgaaacatt gaaaggaaaa
    20461 cagtatgtta aaaaatctaa aatcgttctt gcttcgagga aatgttattg accttgctgt
    20521 cggtgttgtc attgcctctg cttttggtgc tatcgttact tcacttgtaa acgacattat
    20581 cactcctctt attttaaatc ccgctttgaa agctgctaaa gttgaacgta tcgctcaact
    20641 ttcttggcat ggagtcggct atggtaactt cttaagtgct attatcaatt ttatctttgt
    20701 gggtaccgcc ctcttcttta ttatcaaggg cattgaaaaa gcacagaaac tgactggcat
    20761 aaagaaagaa aaaactgccg aaaaaaaacc aaccgaattg gaagtccttc aagaaataaa
    20821 agctctcctt gagaaaaaat aatcgattaa aaggatctag cgcaaagcta aatccttttt
    20881 tctttactct ttgggtaact tgcctgcttt ttcaagcatt tttttgataa gataaggcat
    20941 cttaacattc tcccgccctt ttttctcaat cagttttttc acaaattctg gcatttgtaa
    21001 atcttcagat tcagctaaaa tgtttttcgt ctcgtctgaa ggaactaact catcaaaggt
    21061 ctcttcttct gggagaaatt ccttaaactc ttgattttca ttgactctaa ctgtattgac
    21121 caaagcatca atcaaacgag aatctgtatt tggcattggt ggacgatggt agtttacccc
    21181 aaattcctgg cataagtcat aacattctac atcattgtca aacaagacct caatatgctc
    21241 actgatgaaa ctaataggta caaaaatata atggtctgga tgttctgtct gttctctgag
    21301 atactccaaa acatctggtt taatccatgg aataccaata tcactctcac tctgccaagt
    21361 gttggtatat tgttctgaac tcaagcccag tttttcagcg actagcttgc tattttcgaa
    21421 aatttggtct atataaggat caccaaagtc caaggcaaaa atgggcacac tatgggctga
    21481 aaagatgact ttaaagctgt cttgctttac ttcttctttt aaaatcttag caatttcatc
    21541 tgcccaatag tttaagagca cttcttcctg ataccagtcc ttaatgacca aaaattgaat
    21601 ttgtttgctt tctaaaaatt tttcatagcc catgacagag tagaaagaat aatgtggctc
    21661 caaaatcaag caaatacact gttcaattcc gtctgcttcc atttgaccga tcacatctgg
    21721 aataaaggga ctggaaaact tattagcaaa gtagacactg tattcattac ccagcctagc
    21781 ttctaccaag gtaacctctt gacgggtaat tttttgcaga ggcgtgcctc caattcgtac
    21841 ataattatca tagagagtct gaatctcgtg gtcttggggt ctcaccccac gacgaatatt
    21901 tgtgaaaaaa tcagctacac cttcaaaggt aatctcttct ggtgaaccga aggtcatcat
    21961 taaaattgct tttttcatga ctgcttcctt gtgatgtttt tatcaagttt attttatcat
    22021 taattcatcg ataagtaaac gctaacatag ggacattctc aatcttctgt cttttgtttt
    22081 tctcttcttt ctatgataca atggaaaaaa taaattcaaa aggagttttt ttatgactta
    22141 tccaaatctc ttggaccgct tcttaaccta cgttaaggtc aacacgcgct ctgatgaaca
    22201 ctctactact actccaagta cacagagtca ggttgacttc gcaacaaatg tcctaattcc
    22261 tgaaatgaaa cgtgttggac tgcaaaatgt ttactatcta ccgaatggtt ttgctattgg
    22321 aaccttgcca gccaacgatc cgtctttaac acgtaagatt ggttttatat cgcacatgga
    22381 tactgctgat tttaatgctg aaggagtcaa tccacaggta attgaaaact acgatggtgg
    22441 tgtgattgaa ctagggaatt ctggtttcaa actcgatcca gctgacttca agagtcttga
    22501 aaaatatcca ggacaaacgc tcatcacaac agatggaaca accttgctag gtgctgatga
    22561 caagtcagga attgctgaaa ttatgacagc cattgaatat ctaactgctc atcctgaaat
    22621 taagcactgt gagattcgtg ttggttttgg tccagatgaa gaaatcggtg ttggtgccaa
    22681 taaatttgat gcagaagatt ttgatgtgga ttttgcctac actgttgatg gtggtccact
    22741 aggtgaactt cagtacgaga ctttctcagc cgctggtgct gaattgcatt tccaaggccg
    22801 taatgtccac cctggtactg ccaaagggca gatggtcaat gcccttcagc tagcaattga
    22861 ttttcataat caacttccag aaaatgaccg acctgagtta actgaaggtt accaaggttt
    22921 ttaccatcta atggatgtga caggtagtgt tgaggaggcg cgtgcaagct acatcattcg
    22981 tgattttgaa aaagatgcct ttgaagcgcg taaagcatcc atgcaatcta tcgctgataa
    23041 gatgaatgaa gaacttggga gcaaccgtgt cactctcaac ttgacagacc agtactacaa
    23101 tatgaaagaa gtcattgaaa aagatatgac tccaattacc attgctaaag ccgttatgga
    23161 agatctaggt atcacgccta ttatcgaacc aatccgaggt ggaacagacg gctctaagat
    23221 ttcctttatg ggaatcccaa ctccgaatat ctttgcaggt ggagaaaata tgcacggacg
    23281 ttttgaatac gttagccttc agactatgga acgtgcagtt gataccatca ttggcatcgt
    23341 acgtagctta taaaagctaa aaagacgagg tagctcagct acttcgcctt tctttttatt
    23401 ctactggttt ttcttgattt ccagtagttg tagaagattc tgttgtttta ttttctgaag
    23461 ttgattcagc aggtttagaa tctcttgtat tgcttggttt gttttcgtcg ctagcagttt
    23521 caatgttaga ttctgcagtt gcgtttggtt ggttctcagc actggtgtta tcaccatttg
    23581 cttcagcatt tcttgctgga cttgtttctt cacttgcgct agcttttgac tggatttgat
    23641 gattcaaaac tagaatagct tttgtcgatt caagtaaagc tgttttgtct ttactcttag
    23701 cagaaagttg atctaataat gcatccacct tatcaaagtc cgcatcagat ccattattac
    23761 tttctaaata agagtgaagc gacatgagaa tatcgtagag tttttgatag agtacaagtg
    23821 tctgaggatc ttgctcagca ttttcctttt cttgttgaag ggcgctagcg atacgagtca
    23881 aaacatcttt tacctgactg tttacttcat ccaagtctgc atcagccttg tttgtggcag
    23941 cttttagatt ttctacttct tctgccaagg attgtctgat tccttcttca tggatttgtt
    24001 ccaagagttg atttgccttg ttcaaaagac tttctacttc ttccttgcta tctgtcgcag
    24061 attattggtt gctatctacc atgtactcct aaaacaggag agttataatc caagattaca
    24121 aggccttaca gaaataagaa atccagataa gacaatgttc gtccaagacg ctattcgctt
    24181 cgcacagcag cacggattca atatgcttta attttaaagt ttaggtgtca agacctcttt
    24241 ttagtgtgcc caaaatttag agaagtaatc aatcaactaa cttttatttt tttcaaactt
    24301 tcagtaaact gacctaaagc taactcaatc tgtctttgta gatgcttctg ctatcagcta
    24361 gaagttgatc tacttttgcc aagactgcct tctcatcaaa agttccaggt tgatagttgg
    24421 attgcaggga tggaatcttg tttttcaaag ccgcttcata tcccttagtt tgaaccttga
    24481 tgtagtgatt gtggtcgcca tgaggaatca caaaaccttc tgaatcttca cttataattc
    24541 gattggcatc aaaaaccatg accatcttct tcctcatggt ggacatgtag tgacggatta
    24601 cttaatacag aactagaaga acttcctacc tcttccgtgt tagagtgtga tgggggattg
    24661 ttaagagatg acttaggaat atagtgatag tgttccccat gtcttactat ataagcatca
    24721 cctatatctc tgacaatatc attagggtta aaaacatatg tggctgctaa ttcacctgcc
    24781 gacaagtcac tctcaggaat gaaatgatag tgaccaccat gtggtactat agtaggttga
    24841 aatagaatat gagcaaattg ataaggggat tttaaagtaa tttctaacaa tgatttagaa
    24901 actatgatgt gctattctaa attcaactca ctatatataa ccatcatcgg tagtataacg
    24961 tccctgtaat tttgctacag atacttctgc actagctcct ttatcgtctt taccatgttc
    25021 ttgtttttgg cgattgattt catcttttgt tcgtacattt tctgcatgag cttaatcttt
    25081 aaggtaaaca taatactttc catctacctt aatactatat cctcccttaa cctaactgac
    25141 gatatcttga tctttcggct gatagttggg ggctttcatt aatggctctt cactaaagag
    25201 cgcatcaaaa ggaactttac cattatagca gtgataatga tcgccatgag aagttacata
    25261 accttgacct gtaatcttaa taacaatttg ttttgcttga attccttctt tttgactaac
    25321 ctagtctgga gtcaaatttt cagtcttctt agtgtcttta ttactgttta catatgaaac
    25381 acgattttta tctgtattgg cctgttagct atgttggttc agagcataaa cacacagact
    25441 taaggaaagg ataacaacag atccagctgc tatatatttc tttttaaatt tcataattac
//
LOCUS       DAVLZS010000029        25158 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLZS010000029 DAVLZS010000000
VERSION     DAVLZS010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.029"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            624..1760
                     /gene="lctO"
                     /locus_tag="VYO88_001284"
     CDS             624..1760
                     /gene="lctO"
                     /locus_tag="VYO88_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1719378.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      2014..2102
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            2317..2985
                     /locus_tag="VYO88_001285"
     CDS             2317..2985
                     /locus_tag="VYO88_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1719379.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(3135..3221)
                     /locus_tag="VYO88_001286"
                     /pseudo
     CDS             complement(3135..3221)
                     /locus_tag="VYO88_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            3312..4094
                     /gene="thiM"
                     /locus_tag="VYO88_001287"
     CDS             3312..4094
                     /gene="thiM"
                     /locus_tag="VYO88_001287"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1719380.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALSVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            4096..4725
                     /locus_tag="VYO88_001288"
     CDS             4096..4725
                     /locus_tag="VYO88_001288"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1719381.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      4934..5022
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5283..5843
                     /locus_tag="VYO88_001289"
     CDS             5283..5843
                     /locus_tag="VYO88_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1719382.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            5844..7229
                     /locus_tag="VYO88_001290"
     CDS             5844..7229
                     /locus_tag="VYO88_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719383.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     VQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            7231..7881
                     /locus_tag="VYO88_001291"
     CDS             7231..7881
                     /locus_tag="VYO88_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1719384.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            7892..8584
                     /gene="tenA"
                     /locus_tag="VYO88_001292"
     CDS             7892..8584
                     /gene="tenA"
                     /locus_tag="VYO88_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1719385.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTLNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            8589..9113
                     /gene="thiW"
                     /locus_tag="VYO88_001293"
     CDS             8589..9113
                     /gene="thiW"
                     /locus_tag="VYO88_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1719386.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALVMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            9113..9916
                     /locus_tag="VYO88_001294"
     CDS             9113..9916
                     /locus_tag="VYO88_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1719387.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            9909..10541
                     /locus_tag="VYO88_001295"
     CDS             9909..10541
                     /locus_tag="VYO88_001295"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1719388.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(10750..11556)
                     /gene="thiD"
                     /locus_tag="VYO88_001296"
     CDS             complement(10750..11556)
                     /gene="thiD"
                     /locus_tag="VYO88_001296"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1719389.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLDSVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCT
                     FAAVITAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(11640..11738)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11922..12317
                     /locus_tag="VYO88_001297"
     CDS             11922..12317
                     /locus_tag="VYO88_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1719390.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            12328..12699
                     /locus_tag="VYO88_001298"
     CDS             12328..12699
                     /locus_tag="VYO88_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1719391.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            12709..14952
                     /locus_tag="VYO88_001299"
     CDS             12709..14952
                     /locus_tag="VYO88_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1719392.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            15159..16934
                     /gene="spxB"
                     /locus_tag="VYO88_001300"
     CDS             15159..16934
                     /gene="spxB"
                     /locus_tag="VYO88_001300"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1719393.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            17045..17392
                     /locus_tag="VYO88_001301"
     CDS             17045..17392
                     /locus_tag="VYO88_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1719394.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(17509..18591)
                     /locus_tag="VYO88_001302"
                     /pseudo
     CDS             complement(17509..18591)
                     /locus_tag="VYO88_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            18726..19007
                     /locus_tag="VYO88_001303"
     CDS             18726..19007
                     /locus_tag="VYO88_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1719395.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            19139..20083
                     /gene="manA"
                     /locus_tag="VYO88_001304"
     CDS             19139..20083
                     /gene="manA"
                     /locus_tag="VYO88_001304"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1719396.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(20104..21459)
                     /locus_tag="VYO88_001305"
     CDS             complement(20104..21459)
                     /locus_tag="VYO88_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV1719397.1"
                     /translation="MSEKSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLL
                     IFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSF
                     YSVIGGWILVYLGIEFGKLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIVS
                     RGVQKGIERASKVMMPLLFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYA
                     LGQSFFALSLGVTVMLTYASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFN
                     IQSEGGPSLLFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKR
                     AKWSVILGILTFVFGIPSALSYGVMADVHIFGKIFFDAMDFLASNLLMPFGALYLSLF
                     TGYIFKKALAMEELHLDERAWKQGLFQVWLFLLRFFVSSFQSSSLWSSLPNLCNQKGL
                     E"
     gene            21665..22413
                     /locus_tag="VYO88_001306"
                     /pseudo
     CDS             21665..22413
                     /locus_tag="VYO88_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(22543..23016)
                     /gene="tnpA"
                     /locus_tag="VYO88_001307"
     CDS             complement(22543..23016)
                     /gene="tnpA"
                     /locus_tag="VYO88_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEV1719398.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKARYYKVRSDLIDIIKH
                     LCRCRGVEIIEGHMMPDHVHLLVLIPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTIGLNEKTVAKYIREQEKNDIALDKLSVTEYEDPFSDGGFRTR"
     gene            complement(23702..24650)
                     /locus_tag="VYO88_001308"
                     /pseudo
     CDS             complement(23702..24650)
                     /locus_tag="VYO88_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            24955..>25158
                     /locus_tag="VYO88_001309"
     CDS             24955..>25158
                     /locus_tag="VYO88_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719399.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLIEAMVHKTMFDGM"
BASE COUNT         7504 a         4667 c         5437 g         7550 t
ORIGIN      
        1 aatttatcct ctggctctta ccagaggatt ttttgattca aaaagagact gaatttaagg
       61 agaaaatgaa gtgtagtata ttgaagttga aatagtacac tttgatttct aagacattct
      121 tagaaattgg tttaaattcc ctaagcaatt tgtgcatgtt ttatttcatt ttacgatagt
      181 acgctgaaac tgttcaaaaa gtactagaaa ttgacttgga ttccccaatt gatttgttca
      241 gattcactat aaataaaaaa ttaataagtg ggataggaag ttagcgtcaa ctaggatagt
      301 atcttgctta aacagtatat atgggactga tataagtcca taggtcctat tagaggatgt
      361 tctggtgtct tattcacttg tttttttata gtattagtag atagaatcag caaataaaaa
      421 agtagttcaa atgcctggca gcaaaaaatc tcaacgattt acttaatata gactaaagtt
      481 tagagtttaa ggaaagtagg gctagtatat tgtatgaaaa aataagatgg tttttaagca
      541 aaactcttga aaatgattga aaaaagagtt attatagttg tatagtaaaa agcaaacgct
      601 tacttaatca agggggacag tttatgtcat acaaaacaag caatgcagaa ggtcatgtag
      661 atttcatcaa tacctatgat ttggagccaa tggcgcaaca agttattcct aaagcagcat
      721 ttggctatat cgctagtggg gcggaagata ctttcacttt aagagagaat atccgcgcct
      781 ttaaccacaa actcatcgtt cctcatacac tttgcgatgt tgaaaatcca agtacagaga
      841 ttgaatttgc aggtgaaaaa ctatcttcgc caatcattat ggcacctgtt gcggctcata
      901 aattggcaaa tgaacagggg gaagtggcga ctgcgcgtgg tgtgcatgag tttggttctc
      961 tttatacaac cagttcttac tctactgttg accttccaga gatttctgaa gcccttcaag
     1021 ggacacctca ttggtttcaa ttttacttta gtaaggatga cggtatcaac cgccacatca
     1081 tggaccgtgt gaaggctgaa ggttataaag cgattgtctt gacggcagat gctactgtag
     1141 gggggaatcg tgaagtggat aagcgtaatg gttttgtctt cccagttggc atgccgattg
     1201 ttgaagaata cctgccagaa ggtgctggta aatcaatgga ctttgtttac aaatcagcta
     1261 aacaacgctt gtctccacgc gatgtagaat ttatcgctga atactctggt cttcctgtgt
     1321 atgtcaaggg accacaatgc cgtgaggacg ttgaacgttc gcttgctgca ggagcttctg
     1381 gtatctgggt aaccaaccac ggtggtcgtc aaatcgacgg tggaccagct gcctttgact
     1441 cgcttcaaga agtggcagaa gcagttgata gacgtgtgcc gattgtcttt gattctggtg
     1501 ttcgtcgtgg tcaacacgtc tttaaagcct tggcttcagg agcagacttg gtagctattg
     1561 gtcgccctgt tatttatggc ttggctctcg gtggtagtgt cggtgtgcgt caagtctttg
     1621 aacacttgaa tgcggaattg aagacagtta tgcaattgtc tggagctcag accattgaag
     1681 atgtcaaaca ctttaagctc cgtcacaatc catacaaccc aaccttccca gttgaccctc
     1741 gtgacttaaa attgtattga taaaacagat tgcctccact gaatgtggag gtttttcttc
     1801 gtgtattgga agaataaatc gctatcgaaa actatagtaa aatggaataa aaacagaaca
     1861 aatcaatcag gacatttaaa tcgatttcca acaatgtttt agaagtagag gtgtactatt
     1921 ctagtttaaa tctactatat ataaagatat ttttcggtca aatatcttgc tagggctttc
     1981 attttttgct atactggttc agtaattaaa taatagagac atttggggtg ctttaggctg
     2041 agataatacc cattgaacct gatacagtta agactgacga agggaaatgt gaacagtttt
     2101 ttcgtatggt gaaatgaacg gtctaatctt gtaagtcaac tctaattctt gattgtaatt
     2161 ggagtttttt gtttatataa actggatagg cttgtttagt tagctctctg caaatgctct
     2221 cgatgtgctt taaaaggatc aagtgaaatt acgattttgc ttgatatttc ttggtgtttt
     2281 attaattact aacaagtaaa gagaggagaa gtaaatatgg aaacacaaga ctatgcattt
     2341 cagccaggtt tgactgttgg agaattatta aaaagcagtc agaaggattg gcaggctgca
     2401 atcaatcatc gttttgttaa ggaacttttt gcggggacaa ttgagaataa ggtcttaaag
     2461 gactatctga ttcaagatta tcacttcttt gatgccttct tatccatgct gggtgcctgc
     2521 gtagctcacg cagataaact tgaatccaag cttcgttttg ccaagcaact aggctttctt
     2581 gaagcagatg aagatggtta tttccaaaag gcttttaaag agttaaaagt agcagagaat
     2641 gactatctag aagtgacttt gcaccctgta acaaaagcct ttcaggatct aatgtattcg
     2701 gcggtggctt catcagacta tgcccatctt ttggtcatgc tggtcattgc agaaggtctc
     2761 tatttagact ggggttctaa agatttggct ttacctgaag tctatattca ttcggaatgg
     2821 atcaatctcc acagaggtcc tttctttgca gagtgggttc aatttctggt tgacgaactc
     2881 aatcgtgtcg ataaaaatcg agaagatttg acagaacttc agcaacgctg gaatcaagca
     2941 gtcgctttag aattagcttt ttttgatatt ggttacgatg tctagagaag gctcatgata
     3001 tttacaaatt tgatgaggta agactcttcg aaaatctctt caaaccacgt cagtttcacc
     3061 ttgccgtagg tatggttact gacttcgtca gttctatcca caacctcaaa acagtgtttt
     3121 gagctgactt cgtcagtctt atctacaggc tcaaagcagt gttttgagca acctgcggtt
     3181 agcctcctag tttgctcttt gattttcatt gagtataaat cattcaacgt aaatgaaaaa
     3241 aatttcttaa cgaaagatag agataaatcg aaatcagtag atcgtataaa gtgtaaagga
     3301 aggatttcaa tatgacaagt ttaaaattat taaaagaaaa agcaccattg gtcatttgta
     3361 taaccaatga tgtagtaaaa aatttcacag caaatggatt agtagcactg agcgtctcac
     3421 cagccatgag tgagtttcca gcagatttag aggatttgtt aaagtatgct ggtggtttat
     3481 taataaacat aggaacattg acagatgaaa attggaaatt ataccaagct gctctgaaaa
     3541 ttgcagagaa atataatgtc ccagcagttt tagatcctgt agcctgtgga gcaggagaat
     3601 atagaaaaaa agtagcagat gatctaatca acaattataa actagcagcg attagaggaa
     3661 atgctggcga gattgcctct ttagtaggaa tagatgtggc atctaaagga gtagatagtg
     3721 cgggcgtaga taatattgac gaaattgctc tagcagcaaa tgagaagttc aatattccaa
     3781 tagtagtaac aggtgaagtg gatgccattg ctgttaatgg agaagtggta acgattcata
     3841 atggtagtgc tatgatgccg aaagtcattg ggacaggatg cttattaggg gcagtggtag
     3901 caagctttat cggactagaa aaaggtcaag aattgaaatc attagaaaca gcaatgttgg
     3961 tttacaatat cgctggagaa atggcagaaa aacgtccaaa tggacatctt cctgggacat
     4021 ttaaagttga atttataaat gccttatacg agattacaga tgaagatgta aaggaattca
     4081 aaagagtgaa gtaagatgtt tcataaagaa ttactaaaac tatattttat ttgtggaacg
     4141 actacttgcc aaggaaaaaa tctatataca gtcgttgagg aagccttaaa aggtggtata
     4201 accttatttc aatttcgaga aaaaggtgag ggtgctttag aaggcttaga aaaacttgag
     4261 ctagctatcc aaattaaaga actttgtaaa aaatacaatg ttccatttat cgttaatgac
     4321 gatatagatt tagcaatgga aattgacgcc gatggcgtac atgtaggtca agatgatatt
     4381 ggtgttgatg aaattagaaa attgatgcca gataaaataa ttggtctttc tataagaaac
     4441 gaagaagaat ttcaacaatc aaaagttgaa tatgtagatt atgtaggtgt tgggcctgta
     4501 tttggtaccc agtcaaagga tgatgctggt ggtgctatag gttatgaagg tcttgaattg
     4561 atgagaaaac tattgccaca aatgccttta gttgcaattg gtgggataca gacgaaacat
     4621 attaaagaca ttataaagac caatatggat ggcgtttcaa tcatttcggc aatatcgtat
     4681 gcaaaaaata tagaaaaaac tgttcgggaa atgagtgaac aatagatatc tatccttgga
     4741 ttctaagtaa gtaggatttt ccttttttaa aaagctatgt ccagattcag cttgaatggc
     4801 taattcatca aacaggtcat ttgttttttg caaaagaaag atctgctgtc tttgtgagtg
     4861 caaggctgta tttccagttc aatttcttga actagtataa aatgtgtgtt ataataatca
     4921 cataattaaa taataaagac atttggggtg ctttaggctg agatgatacc cattgaacct
     4981 gatacagtta agactggcga agggaaatgt gaaatgtttt tttcgtatgt cgaaaagaac
     5041 tgtctaatct tgtaagctga actctaattc gtatctgtaa ttagagtttt ttcttttacg
     5101 aaactggatg aagatgatat agtagattga aataagatgc gaacaaatca attagaaaat
     5161 tcaaattaat ttctagaaat attttagtgt tcttgtgtac tgttctaaat tcagtctgct
     5221 atacaaagta tttaggtcgg tcttcttgag tgccccactt ttctttaaaa aaggagtttt
     5281 ttatgttgaa aaaatggcag ttaaaagatg ttatcttgct tgctttcttg tctatctttt
     5341 ttggtggggt tttcgttggt tcaggatatg tgtataatat tctcagtcta ctcttaacac
     5401 ctcttggttt gcaggccttt gccaatgaaa tcctcttcgg tctctggtgt atggctgcgc
     5461 ccattgctgc catctttgtt ccgagagtcg gaagtgcaac gattggagaa gtgctagctg
     5521 cgcttgctga agtcctttat ggtagccaat ttggtctagg agctcttttg tctggcttag
     5581 ttcaaggttt gggaagtgaa tttggtttta tcgtaactaa gaatcgctat gaaagttggc
     5641 tctctctaac tgctaatagt attgggatta cgcttgttag ctttgtctat gaatacatta
     5701 agttaggtta ctacgccttt tcccttccgt ttgtcctttc cttacttgtg gtacgtttta
     5761 tttctgttta tttcttctgt accatcttgg ttcgtgccat tgtcaaactc tatcatcagt
     5821 ttgcaactgg aggaaaagca tagatgggtc tggaactacg agcgattcag tccccaatct
     5881 tctctgagcc gtttgatttt acttttcatg cgcaagcctt taccttgtta gttgggagta
     5941 gtgggtctgg aaaatccagc ctctttcaaa tgattgtcca agttagttct cttccctata
     6001 gcggtcaagt cctgatagat gggagcgagg tcagtcagct ttctatcgtc gaacgtgtcc
     6061 agacggttgg tattctcttg caaaatccta atcatcaatt taccatggag agcttgtttg
     6121 aggagttggt ttttaccatg gaaaatatcg gctatcacct tcaggaaatt gattctaaaa
     6181 tagcagaggt tgtccagcaa tgtcgttgcg aggcaatctt acaccgtccc attcatcacc
     6241 tatcaggtgg ggaaaagcaa aaagcagcgc tggctgtcct ctttgccatg aatcctaggg
     6301 tctatctctt ggatgagccc ttcgcttcta ttgaccgcaa gagcagaatc gagatattgg
     6361 agattctaaa agagttggtc tatgatggga agacagttat tttgtgcgac catgatttat
     6421 ctgactataa agcctatatc gaccatatgg tggagctaag agacggaaaa ctaagggaag
     6481 tgtttcaaat cccttcctat gagatgacac aggttgcttc aaaggaagtt gcttctagcc
     6541 cggaactatt ccatatgaac cgtgtgactg gtgagcttgg taatcgcccc ctcttttcaa
     6601 ttgctgattt cacattctat caagggattt cctgtatcct gggtgacaat ggtgtcggga
     6661 aatcaaccct ctttcggtct attcttcaat ttcaaaagta taaggggagc attacttgga
     6721 agggttcggt cctgaaaaag aaaaagagtt tgtatcgtga tctgactggt gttgttcagg
     6781 aagctgagaa gcagtttatc cgagtcagtc tgcgagagga gcttcaatta gatggacctg
     6841 attctgaaag aaatcagcgg atttttcaag ctttacgata ttttgatttg gagcaggcag
     6901 tcgataagag tccctatcaa ttaagtggtg gtcagcaaaa aattcttcag ctcttgacca
     6961 tcttgaccag taaggcttcc gtgatcttgc tagatgaacc ttttgcaggt ttggatgata
     7021 gagcctgcca ttatttttgc aagtggattg tggaggagag gaatcaagga agaagttttc
     7081 tgctcattag tcatcgttta gaccctttga tttctgtggt tgattattgg attgagatga
     7141 ctagtcaggg tcttcggcat gtgaaagaag tgaccattac caaaccactt acatctcaga
     7201 gtagcaatac ccaaggggag gtgagatagt atggtcaaag tagcaaccca gacaccgatt
     7261 atcagtctct tcttgctgat tttatccttg gaaacatctt tcattccttc gattgctctg
     7321 aatctttcgg tagtcgcatt ttgtattctc tttatgctct attaccgtcg atttaaaatg
     7381 ttagcttgga tgatcatact tgccatttta ccatcttttg ccaactactg ggcagttcag
     7441 ttacacggag atgcttcaca ggcagtcatg cttggaacga gggcctttgt gacagtttgt
     7501 atcggccttg tctttgtttc ctctatttca ctaaaagagc ttctcttgta cttggctcaa
     7561 aaggggctat cacgctcttg gtcctatgcc ttgattgtgg tattcaattc ctttcctctc
     7621 attcagcaag aaatcaagtc cctcaaagaa gcttgcctat tacgtggtca agaactgcat
     7681 ttttggtcac ccttgattta cagtaaggtt ctgatgacag tctttaggtg gcgccatctt
     7741 tacctgagag ctctgtctgc tcatggatat gacgaacatg cacagttgaa gaatagctat
     7801 cggacttttt atattcctaa aaaaacaaaa ttaatctacc tgcttttctt tttattgctt
     7861 caaaccagtc tatttttata aaggagttat tatggaattt acagatattg cgatggaatt
     7921 atccaagaaa gcttggcagg cttcctttca tcatcccttt attttacaat tacaagaggg
     7981 gaatttagaa cctgccattt tccgctatta cctgattcag gatgcctact atctgaaggc
     8041 tttctcagaa atctatcatc ttttggctga taagacttta aaccaagaga tgaaaagact
     8101 cttgaaacaa aatgctcagg gtttagtgga gggtgagtta tttattcgcc aacaattttt
     8161 caaggaattg gaaatcagcg accaggaaat ggagcaacat ccaatcgctc caacctgtta
     8221 tcattacatt tctcatattt ataggcaatt tgcagaaccg aacttagcca tcgcttttgc
     8281 aagcttgctt ccttgtcctt ggttatacca tgatataggc aaatcactta atcttaaacc
     8341 atcaccaaat cctctctatc aacaatggat tgaaacttat attacggatg agttagagca
     8401 acagatcaga gaggagggag cactggtcaa tcagctctat cgagaaagtg acgagacaga
     8461 caagcaaaaa atgctagatg ccttccacat cagtgttcat atggaagcca agttttggga
     8521 aatggcctac caacaccaga catggaagag cgatttacag tctttagaaa aaggagaaga
     8581 atagaagcat gagaaagcac caattacaag ttcacaaatt aaccatttta tctatgatga
     8641 ttgcccttga tgtagtcctt acacctatct ttcgaattga gggaatggca ccgatgtcca
     8701 gtgtagtcaa tattctagcg ggaatcatga tgggacctgt ttatgccttg gtcatggcta
     8761 cagtcacagc ctttatccgt atgacgactc aagggattcc gcctttagct ctcacaggag
     8821 cgacttttgg agcccttctg gcaggtctct tttataagta cggtcgaaaa ttttattttt
     8881 ctgccttggg agaaattgtg ggaacaggta ttattggttc cattgtttcc tatcctgtta
     8941 tggtactctt tacaggatca gctgctaagc ttagctggtt tatctacacg cctcgatttt
     9001 tcggagcaac cttgattggt acagcgattt cctttattgc atttcgattt ttaatcaagc
     9061 aggaattctt taaaaaagtg cagggatatt tctttagtga aaggatagac tgatgcagga
     9121 atttacaaat ccctttccta taggctctag ttccctaatt cactgtatga ccaatgagat
     9181 ttcttgtgag atgctggcaa atgggatttt ggctctggga tgcaaacctg tcatggcaga
     9241 tgatccccgt gaggttcttg attttactaa gcaaagtcag gctctcttca tcaatttggg
     9301 gcatttgtca gctgagaagg aaaaagcaat ccgcatggca gcttcgtatg caaaccaatc
     9361 ttctctcccg atggtagtag atgcggttgg cgtaacgact tcatccattc gtaagagctt
     9421 agttaaagac cttttagact atagacctac ggtccttaaa ggaaacatgt cagaaattcg
     9481 aagtcttgtt ggattaaagc accacggcgt tggggtcgat gcgagtgcta aagatcaaga
     9541 aacggaggat ttgcttcaag tcttgaaaga ctggtgtcag acctatcctg gtatgtcatt
     9601 cttagttact ggccccaagg acctcatcgt ttcgaaaaat caggtcgctg tactggagaa
     9661 tggctgtact gaattagact ggataacagg gacaggagat ttggttggag ccttaacagc
     9721 cgtttttctc agccaaggaa agactggttt tgaagcttct tgcttagcag tctcttatct
     9781 caatatcgct gctgagaaaa tagttgttca aggaatggga ttggaagaat ttcgttacca
     9841 agtactcaat cagctttcgc tcctaagaag agatgaaaat tggctagata ccatcaaagg
     9901 agaggtttat gaatagagaa gcacttagac tatatctggt aaccaatcgc tatcaagatt
     9961 ccgtggaaag ctttcttgca aaagttgaga cggcctgccg ttcaggggtt accatagtcc
    10021 aattgcgaga aaaaaatctc acaaccaatc aatattatca actggcaaaa caagtcaagg
    10081 aaataacaga tgcttatcag gtacccttga taatcgatga tcggttggat gtttgtcttg
    10141 cggttgatgc tgctggtctg catattggag atgacgaact cccagtttcg gttgcccgac
    10201 aagtcttggg tcctgaaaaa atcctcggtg tcaccgctaa aacggttaaa agagctctgg
    10261 aagcggagaa atcaggtgca gattacttgg ggacaggagc catttttccg acaaccacca
    10321 aggaaaatgc acccatcacc ctgatttcaa ccttgaaaac aatttgccaa acggttgcca
    10381 ttccaatagt tgctattggc ggcttgactt cggagaatat tgatcagctt atgggcactg
    10441 gcatagctgg tgtagctgtt gtacgtgatt tgatgcaagc agaagatatt gaggcaaaaa
    10501 cgcaagcctt tttaacaaag ttgcatgaca ttctttccta attaatactc aatgaaaatc
    10561 aaagagtaaa ctagaaagct agtcgcaggt tgctcaaagt actgccttga ggttttagat
    10621 aagactgacg aagtcagctc aaaacagtgt tttgaagttg cagatggaag ctgacgtagt
    10681 ttgaagagat tttcgaagag tataaaaact ctctaattcc cttaaagtgg gaactagaga
    10741 gtttttttct taatctttaa aagttgtatg gttgactgga ccagaaccat gaccaagttg
    10801 aggggcatct tgaatagctt ttgtgataaa ggccttggcc ttatcaactg cctggtaaag
    10861 actcttgccc ttggctagtt cagcagtaat cactgcagca aaggtacatc cagtaccatg
    10921 ggtgtgacag gtttgaattc gtgggctttc ccagacaaat tgttcattct tggtaaagag
    10981 gaaatcttta gcaccacctt tgagatgtcc gcctttgaga tgtccgcctt tgataaccac
    11041 agactgagga ccaaattctt ttaaaatcag gcgaccagca cgctgcatgt cttcggggtc
    11101 atggattgaa aaaccaacaa tctcttctgc ttcaggaaga tttggcgtaa taatagttgc
    11161 tagaggtagt aagtttgttt tgagatagtc tctagcattt gagtcaatca aggcatctcc
    11221 acttgtagca accataacag gatcaaggac atagggacaa tccagttttt taagataggg
    11281 ttggatgatt tccatgattt cagtagtagc caacattcca gtttttacag cctgaggtgg
    11341 aatatcagaa aagacactgt ccaattgggc tttcaacatt tgaggagaaa cgtgctcgat
    11401 tagctgaaca cctctggtat tttgagcgac aagactggtt acaacagcca ttccatagac
    11461 atctctcgct tggaatgact ttaaatctgc cataatgcca gcaccaccac tagggtcagt
    11521 tcctgcaatg gtcaaagcaa cgggtaaata agtcatctaa aacctcccaa ccaactgaag
    11581 tttgtattct taagaacaag ctagtctgtt ttagaaaggc aatagaagac tgctagtccc
    11641 cattatcatt tccacttcca tcagctagca ttacctagat tgagtcagag ggatctaaca
    11701 gtcgttaatc tcagctttac gcacccctag tggttgtttt cttttttctt tagtatagca
    11761 tatttttatt gtttatatag taatatttga ctgcaaatcg tttttcaaat gattaaaatt
    11821 ctatttttcg aagaaaatat tatttctata attgacaaat gtagattttg agagtatact
    11881 gatgagtgta attgacaaat gtagattttg gaggtatggt aatgcagatt tcagatgcag
    11941 aatggcaggt catgaagatt atttggatgc agggggagca gaccagtaca gatttgatta
    12001 gggttttggc agagcggttt gattggtcca agtccactgt tcagacactt ttggctcgtt
    12061 tggttgagaa agagtgtctg actcggaaaa aagaaggcaa gtcctttgtt tattcagccc
    12121 ttttaactct agaccaaagt cgggatttac ttgtccaaga tatcaaagac aaggtttgtt
    12181 cccgtaggat taggaatttg ttggctgact tgattgtaga atgtgaattt actcagactg
    12241 acttggaaga cttggaagct gtgatttcag agaagaaatc aagtgctgta acagaagtaa
    12301 gatgtaattg tatgtaaagg agacgtcatg ttaaatagta ttgtaaccat tatttgtatt
    12361 gcccttatcg cgtttatctt gttttggttt ttcaaaaagc ctgaaaaatc tggacaaaaa
    12421 gcccagcaaa aaaacggata ccaagagatt cgagtggaag tcatgggagg ctatactcct
    12481 gagttgattg tcctcaagaa atcagtgcca gcacgcattg tctttgaccg caaggatcct
    12541 tcaccatgtc tggatcaaat tgtttttcca gattttggtg tacatgcgaa cctgccaatg
    12601 ggggaagagt atgtagtgga aatcacgcct gagcaggttg gagagtttgg ctttgcttgt
    12661 ggtatgaaca tgatgcacgg caagatgatt gtagagtagg tggagactat gacagaaatt
    12721 gtgaaagcaa gcttagaaaa tggcattcaa aaaatccgta tccgagctga aaaaggctat
    12781 catccagccc atatccagct tcaaaaggga attccagctg agattacctt tcatcgtgct
    12841 actccttcaa actgttataa ggaaattctg tttgaagaag aaggtatctt ggaaccaatc
    12901 ggcgtagatg aggagaaagt cattcgtttt acacctcaag aattagggcg acatgaattt
    12961 tcttgtggca tgaagatgca aaagggaagc tatatagtcg ttgagaagac tcgaaaatct
    13021 ctatctctcc tgcaacgttt ttggattact agtatcttta ctgtgcctct tgtgattctc
    13081 atgattggga tgttgacagg tagcattagt catcaagtca tgcattgggg aacctttcta
    13141 gcaacaacgc ctattatgtt agttgcaggt aagccatata tccagagtgc ttgggccagt
    13201 tttaaaaagc acaatgccaa catggatacc ttggttgcgc tgggaactct agtggcttat
    13261 ttctatagcc tagttgctct ctttgctggt ctccctgttt acttcgaaag tgctggattt
    13321 atcctctttt tcgttctttt gggagcagtt tttgaggaaa aaatgagaaa aaatacgtcc
    13381 caagctgtgg agaaattact ggacttgcaa gctaaaaccg cagaagtctt gagtgatgat
    13441 agttatgtcc aagttccttt ggaacaagtc aaggtaggcg acctgattcg agtgcgtccc
    13501 ggtgaaaaga ttgctgttga tggtgtcgta gtagaaggtg tctctagtat tgacgaatcc
    13561 atggtgacag gtgagagtct gcctgtggac aagacagttg gagatactgt cattggctca
    13621 accatcaatc atagtggaac gcttgtcttt agagcagaaa aagttggctc agagactgtt
    13681 ttggctcaga ttgtggattt tgtgaagaaa gctcagacaa gtcgtgcgcc gattcaggac
    13741 ttgacggata agatttcagg gatttttgtc ccagtagttg tcattttagg aatcatgacc
    13801 ttttgggttt ggttcgtctt gctcagggat agtgtggtcg tgcttggagc tagctttgtg
    13861 tcctctcttc tctacggagt ggcggttttg attatcgcct gtccttgtgc cttgggactt
    13921 gcaacaccga cagcccttat ggtggggaca ggacgtagtg ccaagatggg ggttctcctc
    13981 aaaaatggaa ctgtcttaca ggaaatccag aaagttcaaa ctcttgtctt tgataagacc
    14041 gggactttga cggaagggaa acctgtggta acagatatca tcggcgacga agtagaagtg
    14101 tttggattgg cagcctcctt ggaagatgct tctcaacacc cactggctga ggctatcgtt
    14161 aagcgagcga gtgaagctgg acttgagttt caaactgttg aaaattttca gtccttgcac
    14221 gggaaaggtg tttcagggcg aatcaatgga aaacaagttt tacttggaaa tgctaaaatg
    14281 ctggatggta tggatatttc taatacttat caagataaac tagaagaact agaaaaagaa
    14341 gctaagacag ttgtgttctt agctgttgac aatgaaatca aaggcttgct tgctttgcaa
    14401 gatattccta aggaaaatgc taagctagcc atcagtcagc taaaaaaacg tggtctccga
    14461 acagtcatgc tgacaggaga caatgctggt gtggcgcgtg ctattgcaga tcaaatcgga
    14521 attgaagagg tcattgcagg cgtcttgcca gaagaaaaag cccatgaaat ccataaactg
    14581 caacagtcag ggaaagtagc ctttgttggg gacggtatca atgacgctcc tgcccttagt
    14641 gtagcagatg tggggattgc tatgggagct ggaacagata tcgccatcga gtcagcagat
    14701 ttggtgttga caaccaataa tcttttagga gtggttcgtg cctttgatat gagtaagaaa
    14761 acctttcatc gaattctact caatcttttc tgggctttta tctacaatgt tgtcggaatt
    14821 ccgattgcag caggagtctt ttcaggtgtt ggactggctc tcaacccaga attggcaggt
    14881 ctagccatgg cctttagttc tgtatctgtt ctgaccagtt cccttctgtt aaattttagt
    14941 aaaatagact aaaagtaatg actagatttc tttgttataa aacagaaata acagaacttt
    15001 caaaactgta ttagaataga gaatagagag ttttgagcag atttttagaa aagtcagcat
    15061 aaatatgata cagtggaata gtaaaaattt ggagaacgtt tccaattcta tgtaatcgta
    15121 ttctccaaat ctaaaaaaat tgaaggagag ttatcattat gactcaaggg aaaattactg
    15181 catctgcagc aatgcttaac gtattgaaaa catggggcgt agatacaatc tacggtatcc
    15241 catcaggaac actcagctca ttgatggacg ctttggctga agacaaagat atccgcttct
    15301 tacaagttcg ccacgaagag acaggtgctc ttgcagcggt tatgcaagct aaattcggcg
    15361 gctcaatcgg ggttgcagtt ggttcaggtg gtccaggtgc gactcacttg attaacggtg
    15421 tttacgatgc agctatggat aacactccat tcctagcgat ccttggatca cgtccagtta
    15481 acgaattgaa catggatgct ttccaagagc ttaaccaaaa cccaatgtac aacggtatcg
    15541 ctgtttacaa caaacgtgta gcttacgctg agcaattgcc aaaagtaatt gacgaagcct
    15601 gccgtgctgc aatttctaaa aaaggtccag ctgttgttga aattccagta aacttcggtt
    15661 tccaagaaat cgacgaaaac tcatactacg gttcaggttc atacgaacgc tcattcatcg
    15721 ctcctgcttt gaacgaagtt gaaatcgaca aagctgttga aatcttgaac aatgctgaac
    15781 gcccagttat ctatgctgga tttggtggtg ttaaagctgg tgaagtgatt actgaattgt
    15841 cacgtaaaat caaagcacca atcatcacaa ctggtaaaaa ctttgaagct ttcgaatgga
    15901 actatgaagg tttgacaggt tctgcttacc gtgttggttg gaaaccagcc aacgaagtgg
    15961 tctttgaagc agacacagtt cttttccttg gttcaaactt cccatttgct gaagtttacg
    16021 aagcattcaa gaacactgaa aaattcatcc aagtcgatat cgacccttac aaacttggta
    16081 aacgtcatgc ccttgacgct tcaatccttg gtgatgctgg tcaagcagct aaagctatcc
    16141 ttgacaaagt aaacccagtt gaatcaactc catggtggcg tgcaaacgtt aagaacaacc
    16201 aaaactggcg tgattacatg aacaaactcg aaggtaaaac tgagggtgaa ttgcaattgt
    16261 atcaagttta caatgcaatc aacaaacatg ctgatcaaga cgctatctac tcaatcgacg
    16321 taggtaacac tactcaaaca tctactcgtc accttcacat gacacctaag aatatgtggc
    16381 gtacatctcc gctctttgcg acaatgggta ttgcccttcc tggtggtatc gctgctaaga
    16441 aagacaatcc agatcgccaa gtatggaaca tcatgggtga tggagcattc aacatgtgct
    16501 acccagacgt tatcacaaac gttcaatacg accttccagt tatcaacctt gtcttctcaa
    16561 atgctgagta cggcttcatc aagaacaaat acgaagatac aaacaaacac ttgtttggtg
    16621 tagacttcac aaacgctgac tacgctaaaa ttgcggaagc tcaaggagct gttggattca
    16681 cagttgaccg tatcgaagac atcgatgcag ttgttgcaga agctgttaaa ttgaacaaag
    16741 aaggtaaaac tgttgtcatc gatgctcgca tcactcaaca ccgtccactt ccagtagaag
    16801 tacttgaatt ggatccaaaa cttcactcag aagaagctat caaagccttc aaggaaaaat
    16861 acgaagcaga agaactcgta ccattccgtc tcttcttgga agaagaagga ttgcaatcac
    16921 gcgcaattaa ataattcctc tcgccgaaaa tcaaatatga aacttgtaga ctttattctt
    16981 tgattttcat agagcagaac tttaaaagat cggagcaatc cggtcttttt atggaggaga
    17041 gtaaatgaat ttaaatcaat tagatattat cgtttcaaat gttccccaag tctgtgctga
    17101 cttggagcat attttggata aaaaggcaga ttatgctgat gatggttttg ctcagtttac
    17161 gattggtagt cactgcctta tgttgtcaca aaatcatttg gttcctttgg aaaactttca
    17221 gtcaggaatc attattcata tcgaggttga ggatgtagac cagaactaca aacggttgaa
    17281 cgagcttggt ataaaggttt tacacggacc aactgtaacc gattggggaa cagagtcctt
    17341 attagttcaa ggacctgctg gtctagtgct tgatttttat cgtatgaaat aggtcgcgta
    17401 gtcatttgac gttaacctta gctattttta aaatagaaat tgagaatatg aactattgaa
    17461 agatcggagt aatccggtct ttttatataa agaaattgca tataatactc atctgctttc
    17521 aaaaagcatt ctagtccatc tccgattaac gatggacttt atcacctcct tctccagtcc
    17581 ttgtatgaca tcttggagtt gattcatgac atcttccaaa gttcgaaagg ctttattctt
    17641 aaatccacgt ttacgaatct ctttccacac ttgttcaatg gggttcatct ctggtgtgta
    17701 tggaggaatg aaggtaaaac caatattagt cggaatcttt aagatacttg atttatgcca
    17761 tatagcatgg tccataacga gtaaaagata atcatctgga taagcttgtg aaagctcttc
    17821 taaaaaggcg ttcatccact cagtattaca tccaccagct attaagaaaa atgattcgcc
    17881 tgtatgggca tcaacagctc cataacaata gcgaaattct cgtatatagt gactatggac
    17941 atgtggacct actcctattg gagaccaaca agatcccagt ttactgattc taccgaaacc
    18001 agcttcatct tggtacatca agcgaacctt atgaaaacgt ctactatatt taaaacgctt
    18061 tcttgtcttc ttgaattgag attttatttt tagacgcgac aatggtttga gcgtctgctt
    18121 tcctaggatg ttctggactt ggcgtaatat ttcgccaacc atggcacttc aacagttgat
    18181 agaaggtatc acgtgtgtag gaatgaccta actccttttt ataagcctga aataaggcat
    18241 caattgtaac aaattctcct gcctctgtag ccttcaaatg acgggcaaga aagactttct
    18301 attgctcaac cgtcatatat gcatggttac gaccaccacg tgtttcttga aggagagagt
    18361 cgagtccgaa ctcctcatat ttttttacat ttcgccaaat cgttgtttga ttacagtcta
    18421 aaagctctat aatctcttta taagatttgc ccatcagacg aaatataata gattgaaact
    18481 agaatagtac acctctactt ctaaaacatt gttaaaaatc gatttgactg tcctgatcga
    18541 tttgtcctgt tcttgtttcg ttttactata gaacgatttg aaggtgttta tgatatttag
    18601 ctgtactaga gtcttttaaa agtgttttga tggtttggat ttcttcttta attgatttca
    18661 tattactatt gtataatgct ttttgatttt agtatagtat tatcgtagaa aatggactcg
    18721 gtgctatgga tacaccggat gagaatggtt atgtagcaga tgactatcgg attacttact
    18781 tagaggccca catcaaggcc atgcgagatg ccatttacaa agacggggtt gacttgcttg
    18841 gttatacgac atggggctgt atcgattcgg tttcagctgg cacaggggaa atgaataagc
    18901 gctatggctt tatctatgta gatcgagata atgtaggaaa tgggactctc aaacgtagca
    18961 agaagaagtc cttctattgg tacatgtcat ttatagcaat ggtgtaagca tcgagtagag
    19021 cacatttgtt tactattttt ataaaatctt ctccctgctt tataagatgt aaaaaagagt
    19081 tcaattcgaa ctcttttttt gctataatga ggggagaaaa atcagacagg agatcgacat
    19141 gtcagaacca ttatttttac aatcagttat gcaagaaaaa atctggggtg gagccaagct
    19201 acgtgatgag tttggctacg acatcccaag tgaaaaaatc ggagaatatt gggccatctc
    19261 agcccatcca aatggagtct ctaaagttgc caatggtcgt tacgagggaa cagatcttgc
    19321 tactttgtat gcggaacacc gtgaattatt tggcaatcgt ccagaacctg tatttccact
    19381 tttgaccaag atcctcgatg ccaacgactg gctcagtgtc caagttcacc cagacgatgc
    19441 ttatggactc gagcatgaag gcgaactcgg aaaaacagaa tgctggtaca ttatcgcagc
    19501 ggatgaaggt tcagagatta tctacggtca caatgccaag tcaaaagaag aactccgcca
    19561 gcaaatcgag gacaagaact gggatgactt gttgaccaaa gtccctgtta aggctggaga
    19621 tttcttctat gtaccaagcg ggactatgca cgctatcggg gcgggtatct taatccttga
    19681 aacccagcag tctagcgata ccacctatcg cgtctatgac tttgaccgca aggatgacaa
    19741 aggcaacttg cgtgaacttc atcttgaaaa atccatcgat gtcttgaaca ttggtgagcc
    19801 agcaaatagc cgtcctgtaa ctgttaaagc agatgatttg cgttccactc tccttgtatc
    19861 taatgatttc ttcgcagttt acaagtggga aattactgga aaagttgact ttgaaaagac
    19921 agctgactac agcttattga gtgtcttagc tggtcaaggt cagctaactg ttgacgggaa
    19981 aaattatcca attcaaaaag ggagacactt tatcctacca agtgatgttg aagcttggac
    20041 tctggaaggg caaggtttgg aattgattgt tagccatcca taaaaagaaa gggcctgagt
    20101 tcactactca agtccttttt gattacataa attgggcaat gaagaccaca atgatgatga
    20161 ttggaatgac gaaacgaaga aacgaagaag gaagagccag acttggaaca gtccttgttt
    20221 ccatgctctt tcatcgagat ggagttcctc cattgcaaga gcctttttaa agatatagcc
    20281 tgtaaaaagt gaaaggtaga gagctccaaa tggcatgagg agattggaag ccaagaagtc
    20341 catagcgtca aagaagatct taccaaaaat gtgaacatcc gccatgacac cgtaagatag
    20401 ggctgaagga atgccaaaga caaaggtcaa aattcctaaa ataacactcc atttggcacg
    20461 tttgctgtta tcctggttgg tgatattgcc cacattgatc tccagcatca cgacagaaga
    20521 agtgacagtc gcaaagagga agaggacgta gaaaatggtt ccaaaaggca tcttgtcaaa
    20581 gagttgaggt aagacgataa agagcaagct cggtccccct tcagactgga tattgaaggg
    20641 ggatcgagct tggaaaatgg ctagacctgc catgatggat atcgagatat tcatggctac
    20701 gatggagatt cctgactgga ctagattggt tttcttgtcc aagtaagaag cataggtcaa
    20761 catgactgta acccctagtg agagggcaaa gaaagattgt cccagagcat agaggagacc
    20821 agcgctagtc agttttgaaa agtctggttt gaggaagtaa agaacccctt ccatggcatt
    20881 tggcaaactg agagagcgac cgatgataac aacaaagatg ataaagagca ggggcatcat
    20941 gactttcgaa gctctttcaa tccctttttg aaccccacgt gatacaataa agatatttaa
    21001 taagataaag gctgcttgag ctactagggc aatggctgga tttgaaatga ttgaagtaaa
    21061 taactgagca taatcacccg ttccaccaag ttggaacaat ttcccaaact caatacctag
    21121 atagactaga atccatcctc cgataacact gtaaaaagat aagaggataa agagggcaaa
    21181 ggcgccaatc caaccgataa agttgtactt gttattcttg cccagttttc caaaggtttt
    21241 gatagcggaa acgccagcac tacggccaag ggcaaactca gccagcagga gagggaaacc
    21301 gattaaaata gtggaaatga gaaagattag taaaaagcct ccaccgccat tagcagcagt
    21361 catgtaggga aacttccaaa cggaaccaag cccgatgacc gagccagcag atgctagaat
    21421 aaagccaagt ttcgaccccc attgtgattt ttctgacata gttaaactct aatctccttt
    21481 ttcaaaataa gaaaaagcta cttgagttgt caaatagcct tctgtttgat tgatagactt
    21541 gactatccta ttatgttttc taaggtctgt caagaaaacc attttcaagt tttcacacct
    21601 ttctcaaaaa cgcttgactc tgacctaagg ggaggggtta tactatcatt gtaaggagga
    21661 aatcatgtac catataaaag aagctgcgca gctttcaggt gtctctgtca agaccctgcc
    21721 ctgcatcact atgacaagat aggactcttg gtccccttaa agtcggaaaa cggctatcga
    21781 acctatagtc aagaggattt ggaacgcctt caggtcattc tttactacaa atatctaggc
    21841 ttttctttag agaaaatagc agaactgtta aaggaagaaa ggacagattt attgctccat
    21901 ttgactaggc agttggacta tctaactcgc gaaaggcaac atctggatac cttgatttcc
    21961 accttgcaaa aaactattca agaacaaaaa ggagaaagaa aaatgaccat tgaggaaaaa
    22021 ttcacgggat ttagctatca agacaatcaa aaataccacc aagaagcggt agagaaatat
    22081 ggtcaagaag tcatgggaca agcgctcgaa cgccaaaaag gtcacgaaga cgaggctacg
    22141 gccgccttta accaagtctt tcaaactttg gcacaaaatc ttcaagttgg tttacctgca
    22201 acagcaaccg aaaaccaaga gcaagcagcc aagctcttgc aagctattcg cacttatgga
    22261 tttgattgct ctattgaggt attcggtcat atcggtaaag gttacgtcta caacccagag
    22321 tttaaggaaa acattgacaa gtttggttct ggaacagccc agtacacgtc agatgccatt
    22381 gcggcttacg ttcagagaaa tgcagagtca taaccacccg tgaaaacggg tgtcttgtac
    22441 accggctata agccgtttct ctccagtggc gtctaaagac gctcgctgaa cttcgttcag
    22501 gtcgtgctat attacttgac taatgcccgt cacaacgggc ttttaccttg ttctaaatcc
    22561 gccatcagaa aatggatctt catattctgt tacactcagc ttatcgagtg caatgtcatt
    22621 cttttcctgt tcgcgaatat atttagctac ggtcttttcg tttagtccaa tggtgcttac
    22681 atagtagccc ctagcccaga actttcgatt tccatactta tattttaaat tagcgtgctt
    22741 atcaaatatc atcaatgcac ttttactctt gagatacccc ataaaatcgg aaatcgaaag
    22801 tttgggaggt atcagtacaa gcaggtgtac atggtctggc atcatatgac cttcgataat
    22861 ctccacgccg cgacaacggc agagatgttt gataatatct atcaaatccg acctgacttt
    22921 gtaatatctc gccttacggc gatacttagg tgtaaaaact atatgatatt tgcacatcca
    22981 tttggtatgt gataaactgt aactggtttt agccatttat ttttcctcct ttatctaacc
    23041 tgaacaatta gattatactt ggaaaaataa atggaagctt gaagccttgt cagccaccag
    23101 catagctggt ggttttcttg tttttctata cgagaaaaac tggcttgaag ccataataaa
    23161 tgagcctggg acaaaatagt tctcgaccac aaaaaagcta gagatttcca attgtggaac
    23221 tctagctttt taattttgag tcgttctctt attgtatttt aggagcttat tggccatgag
    23281 taccaatccc atatcaattt tcacttgacg cttacctctc agattacatt tcttgtaccc
    23341 caaacaagcc gtcaggagat aaaagttcct gacattcttt agctttcaag ttttgacagc
    23401 cttcgttcat atacagtccc ttttgagggg ctgcttcaga ttgaacagcg tagtaaacct
    23461 tgatttcctg ttgaaagttc gtctgtgttt tctgatgttt gatatggtga aaacgatagc
    23521 accagccgtc aggatgtgta tagctatcct tcttgtcatc atagtgccaa ttcgctcagt
    23581 ttctagctga ctgtttatat agtggattga aataagatgt gaacaaatat attaagaaag
    23641 tcaatttaat ttctagcaat gttttagaag ttttagtgta ctgtttcaac ttcaatctat
    23701 tataccctct cttctgttct ttatcaaaca tggcatattt aatcagatgg ttcacctcct
    23761 tttcctctaa acgaaggagg ttctcttcac ttccatatcc agcatctgcg acaactgtct
    23821 tcaattcatg cgcataaaag tggcatctgg atcggttttg gaaaagctgt taggtccttg
    23881 aaatgtctcc tgatagttct catatttttt agcacatact gaaaaatcct ccttgacttt
    23941 acgcaagact ttcttgagtt tacgacgttg ggttttacgt tcatccttcc ctttaacggg
    24001 tatctcctca atgtcttggt tcaatttttc caattcttct tcaaggattt gagcgaatgc
    24061 aagcaactgg aggagataag ctcttgtgta tccagttcga tagcttgatg aatcagggga
    24121 gtgatttctt cttgaaaata gacctgtatc tgttcttgaa gtttggcgga gaatttctct
    24181 gtcgcgttct tccacacgaa actatacttg ttggcattgg cttcaatctt agtcccgtca
    24241 ataaacagac aatctaaggt cactaactct tccattttta aacgaagatt gaggtcgatg
    24301 aaaagatcac gaatgagttc ttccatccct tcagcgacac gaaaacgatt gatagtgcgg
    24361 tagctaacaa ccaactgtcc tgttaggtac tgcatagcga gattttcaat catccttttt
    24421 tcgatttttc gaccagagaa aatcccttgt gaataggcaa atagaagggt agatacaagc
    24481 attttagggt gataagacgg gtgaccaaag gcatgataga aggcgtggaa gtgacaatcc
    24541 tccaaagtat tcaccacttt ttcaatagta aagacgagat ggtcttgtgg caagaaagaa
    24601 ctgatttcta gtggtaaagt tgtttgattt gtgttatagt gaatatgcat gggatagcct
    24661 ttctaaatgg tttattgtgt aattctatag cgaattgaat caagaacagt acactacgac
    24721 tgctaaaaaa attctaggaa ttaaattgac tttcctaacc gatttgttca catcttattt
    24781 caatctactt tattttacca agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt
    24841 tgcttttttt ggaaataaga gactattgtc ccagactcat tatttttttg aaagttaata
    24901 ttgagttaac atagaaatgt tatagtgaca ggagacaaaa gaaaggatac taatatggta
    24961 ttagcgatta ttttagtaac attccttatt cgattgattt ttttaaagcg ttcgatagag
    25021 aatgagaaac gaatccttag caatggcggg aaagaatttg gagttgagaa tacaaaacga
    25081 ttaacgttgg ctcatattgt tttttatctc tcttgcctca ttgaagcaat ggtgcacaag
    25141 acaatgtttg atggtatg
//
LOCUS       DAVLZS010000030        23299 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLZS010000030 DAVLZS010000000
VERSION     DAVLZS010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.030"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            584..2737
                     /locus_tag="VYO88_001310"
     CDS             584..2737
                     /locus_tag="VYO88_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1719400.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTFAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGDFYAHLVNS"
     gene            2750..4099
                     /locus_tag="VYO88_001311"
     CDS             2750..4099
                     /locus_tag="VYO88_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1719401.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4269..4976
                     /locus_tag="VYO88_001312"
     CDS             4269..4976
                     /locus_tag="VYO88_001312"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1719402.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5178..8903
                     /locus_tag="VYO88_001313"
     CDS             5178..8903
                     /locus_tag="VYO88_001313"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1719403.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLTLATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLGGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKK
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            8996..10438
                     /locus_tag="VYO88_001314"
     CDS             8996..10438
                     /locus_tag="VYO88_001314"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1719404.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FYDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10475..11497
                     /locus_tag="VYO88_001315"
     CDS             10475..11497
                     /locus_tag="VYO88_001315"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1719405.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKTLEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11494..12039
                     /gene="purN"
                     /locus_tag="VYO88_001316"
     CDS             11494..12039
                     /gene="purN"
                     /locus_tag="VYO88_001316"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1719406.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12123..12632
                     /locus_tag="VYO88_001317"
     CDS             12123..12632
                     /locus_tag="VYO88_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1719407.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVRVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12657..14204
                     /gene="purH"
                     /locus_tag="VYO88_001318"
     CDS             12657..14204
                     /gene="purH"
                     /locus_tag="VYO88_001318"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1719408.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAGKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14327..15589
                     /gene="purD"
                     /locus_tag="VYO88_001319"
     CDS             14327..15589
                     /gene="purD"
                     /locus_tag="VYO88_001319"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1719409.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVKKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            15992..16480
                     /gene="purE"
                     /locus_tag="VYO88_001320"
     CDS             15992..16480
                     /gene="purE"
                     /locus_tag="VYO88_001320"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1719410.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTILPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16467..17558
                     /gene="purK"
                     /locus_tag="VYO88_001321"
     CDS             16467..17558
                     /gene="purK"
                     /locus_tag="VYO88_001321"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1719411.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17568..17795
                     /locus_tag="VYO88_001322"
                     /pseudo
     CDS             17568..17795
                     /locus_tag="VYO88_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
     gene            17858..19156
                     /gene="purB"
                     /locus_tag="VYO88_001323"
     CDS             17858..19156
                     /gene="purB"
                     /locus_tag="VYO88_001323"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1719412.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19211..23149)
                     /gene="strH"
                     /locus_tag="VYO88_001324"
     CDS             complement(19211..23149)
                     /gene="strH"
                     /locus_tag="VYO88_001324"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1719413.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMDFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQEEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSRSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEILSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
BASE COUNT         6322 a         4656 c         5555 g         6766 t
ORIGIN      
        1 tctaaaaata taaccttaag ttttagcatt ttactttgtt atttatttaa tccatcggat
       61 ataaagtttg cctatttcag cgtattgaca gtattactaa ttgggataac aaattatgcg
      121 agatttaaaa atttaagatt gacagtagtg ttttctgtac catttttatt taatgctata
      181 atgtctatta taaatagttt ttagaaatac taaaattttt ttctttactt aataatgata
      241 tgaaatcatt tcggttttgt taacttgtaa ttcttatatt ttctaggtag aacgtttgtt
      301 ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat ttgggaagga
      361 agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag tttatactct
      421 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg actgacttcg
      481 tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt
      541 tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat ttgggaaacg
      601 tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag ccatggtttt
      661 tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta agacgaccat
      721 ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggtt ttgagacgcg
      781 agccattaag gcggatatga cgctttttga cttgccggat ttgacttttc cttttgttgc
      841 ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc aggataagga
      901 tagcattcat attgccgatc cagatcccgg ggtgaagttg actaaactgc cacgtgagcg
      961 ttttgaggaa gaatggacag gagtgactct ttttatggca cctagtccag actataagcc
     1021 tcataaggaa caaaaaaatg gtctgctctc ttttatccct atattagtga agcagcgtgg
     1081 cttgattgcc aatatcgttt tggcaacact cttggtaacc gtgattaaca ttgtgggttc
     1141 ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt cgacactagg
     1201 gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt cttacgctca
     1261 ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt tgtcctatat
     1321 caagcatgtt tttcacctcc ctatgtcctt ctttgcgaca cgcaggacag gggagatcgt
     1381 gtctcgtttt acagatgcta acagtatcat cgatgcgctg gcttcgacca tcctttcgat
     1441 tttcctagat gtgtcaacgg ttgtcattat ttcccttgtt ctattttcac aaaataccaa
     1501 tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct ttgcctttat
     1561 gaagccgttt gaaaagatga atcgggatac catggaagcc aatgcggttc tgtcttcttc
     1621 tatcattgag gacatcaacg gtattgagac tatcaagtcc ttgaccagtg aaagtcagcg
     1681 ttaccaaaaa attgacaagg aatttgtgga ttatctgaag aaatccttta cctatagtcg
     1741 agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttgctta atgtcggcat
     1801 tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc agttgattac
     1861 ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca atctgcaaac
     1921 caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc tagtagcttc
     1981 tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag atatgacctt
     2041 caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata tcaatttaac
     2101 cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta agacgacttt
     2161 tgccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc tgggtggtgt
     2221 caatctcaat cagattgata aaaaagccct gcgccagtac atcaactatc tgcctcaaca
     2281 gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca aggaggggac
     2341 gacacaggaa gatatcttac gggcggtcga attggcagag attcgagagg atatcgagcg
     2401 catgccactg aattatcaga cagaattgac ttcggatggg gcagggattt caggtggtca
     2461 acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct tgattttgga
     2521 tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata atctcattgc
     2581 tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc ggacagagaa
     2641 ggtggttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg atttgcttgc
     2701 acagggagac ttttacgccc atttggtcaa tagctagaaa gaggagagga tgaaaccaga
     2761 atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca gtagtgtgat
     2821 tgtacccatg gcccttctgc tcgtgttttt acttggcttt gcaactgttg cagagaagga
     2881 gatgagtttg tccactagag ctactgtcga acccagtcgt atccttgcaa atatccagtc
     2941 aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg ttaagaaggg
     3001 ggatcttttg gttcaatacc aagaaggggc agagggtgtc caagcggagt cctatgccag
     3061 tcagttggac atgctaaagg atcaaaaaaa gcaattggag tatctgcaaa agagcctgca
     3121 agaaggggag aaccactttc cagaggagga taagtttggc taccaagcca cctttcgcga
     3181 ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg agaccatcgc
     3241 gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca tcagtcaaac
     3301 agaggctaaa attcgcgatt accagacagc taagtcagct attgaaacag gtacttcctt
     3361 ggccggtcag aatctagcct actctcttta ccagtcctac aagtctcagg gcgaggaaaa
     3421 tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc agttagaatc
     3481 tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag cctatgcgtc
     3541 agggttaagc agtcaattgg aatcccttaa atcccaacac ttggcaaagg ttggtcagga
     3601 attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg tacagggaaa
     3661 tcttttagac aaggggaaaa ttacggcaag tgaggatggg gtgcttcatc ttaatcctga
     3721 gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt atccatcttt
     3781 ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg tagcaagaat
     3841 caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc aactttttct
     3901 agattctact attacaagta ttgatgcgac agctactaag actgagaaag ggaatttctt
     3961 taaaatcgag gcggagacta atctaacttc ggagcaggct gaaaaactta ggtacggggt
     4021 ggaaggccgt ctacagatga ttacgggcaa gaaaagttat ctacgttatt atttggatca
     4081 atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta aactgtgaga
     4141 aagattcttc ttgcagtttt ttctttacaa tttttgaaaa acacctgcta tttattcggt
     4201 taaattcttg tgttttttgg ttttttgtgg taaaatgtgc tcaagtaata cgaaaggcga
     4261 actttaaaat gtcaaaacaa ttgatctatt cgggaaaagc taaagatatc tatacaactg
     4321 aggatgaaaa tcttattatt tcaacttaca aggaccaggc gactgctttc aatggtgtca
     4381 agaaggagca gattgcaggt aagggagtct tgaataatca gatttcatct tttatttttg
     4441 agaaattaaa tgcggctggt gtggcgactc actttgtgga gaaactttca gacacggaac
     4501 aactcaataa aaaggttaag attattcctt tggaagtcgt gctccgcaac tatactgctg
     4561 gttccttttc aaaacgtttt ggtgtggatg agggaatcgc cttggagact ccgattgtcg
     4621 aattttacta caaaaatgat gatttggatg atccatttat caatgatgag catgtgaaat
     4681 tcctacagat tgcgggtgac cagcagattg cctacttgaa ggaagaaacg cgtcgtatca
     4741 atgaactatt gaaagtctgg tttgctgaga ttgggcttaa attgattgac tttaagctag
     4801 agttcggttt tgacaaggat ggcaagatta tcttggcaga cgaattttca ccagataact
     4861 gccgcttgtg ggacgctgat ggcaaccaca tggataagga tgttttccgt agaggattgg
     4921 gagaactaac cgacgtttat gagattgttt gggaaaagtt gcaggaattg aaataatctg
     4981 tttgcaacgg aaaaccttcg tctctcaact aaaaggactc aggctgaaaa ggtcccccag
     5041 accttttcac tctgtagaga actaggtgaa ctaacagatg tttacgaaat tgtctgggaa
     5101 aagttgcagg gtttaaaata acaacctcaa ggctgtttgg gaatattgca agagctgaaa
     5161 taaaggaata agaattgatg gataaacgta tttttgttga aaaaaaggct gattttcagg
     5221 tcaagtcaga gagtttggtt agagagctcc agcacaactt gggactgtca agcttgaaaa
     5281 gtattcgtat tgtgcaagta tatgatgtat ttgacttggc tgaggacttg tttgcacctg
     5341 cagagaagca cattttctct gagcagggaa ccgaccatgt tttagatgaa gtatctgtgc
     5401 aggcggatct tgctaactat gctttctttg ccattgaaag tctgccaggg cagtttgacc
     5461 agcgtgcagc ttcgtcacag gaagccttgc ttttgttggg aagttcgagt gacgtgacag
     5521 tcaacacagc ccaactttac ttggtgaata aagatattga tgcgactgag ttggaagctg
     5581 tcaaaaacta cctgctcaat ccagttgatt ctcgtttcaa ggatatcacg acagggattg
     5641 ccaagcagga gttttcagag tcagacaaga ccattccaaa attgactttc tttgaaagct
     5701 atacagcaga agactttgct cgctacaagg ccgagcaagg gatggccatg gaagtggatg
     5761 atttgctctt tatccaagac tactttaagt caatcgggcg cgtgccaact gagactgaac
     5821 tcaaggtttt ggacacttac tggtctgacc actgccgtca tacgactttt gagacagagt
     5881 tgaaacacat cgacttttca gcttctaaat ttcaaaagca attgcagtca acctatgaca
     5941 agtatattgc catgcgcgag gagttaggtc ggtctgaaaa accacaaacc ttgatggata
     6001 tggcgactat tttcggtcgt tatgagcgtg ctaatggacg attggatgat atggaagtct
     6061 ctgacgaaat caatgcctgc tcagttgaaa ttgaagtgga tgttgatggt gtcaaggaac
     6121 cttggctcct catgtttaaa aatgaaaccc acaaccatcc aacagaaatt gagccatttg
     6181 gtggagcggc tacctgtatc ggtggagcta ttcgtgatcc gttgtcaggc cgttcctatg
     6241 tttaccaagc catgcgtatt tcaggtgctg gtgatattac agcaccgatt tcggaaactc
     6301 gtgctgggaa attgccacaa caagtcattt ctaaaacagc agctcatggt tattcttcat
     6361 atggtaacca gattgggctt gccacaacct acgttcgtga atacttccac ccaggctttg
     6421 tagctaaacg tatggaactt ggtgccgttg ttggtgcggc tcccaagggc aatgttgtcc
     6481 gtgaaaaacc tgaagcaggt gatgtgatca tccttctcgg aggcaaaaca ggtcgtgatg
     6541 gtgtcggtgg tgcgacgggc tcttctaagg ttcaaacagt tgagtctgta gagactgctg
     6601 gtgctgaggt tcaaaaagga aatgccatcg aagaacgcaa gattcagcgc ctcttccgta
     6661 atggcaatgt cactcgtctg atcaagaagt ccaatgactt tggggcaggc ggcgtctgtg
     6721 tggctatcgg tgaattggca gacggtcttg aaatcgacct caacaaggtg cctcttaaat
     6781 accagggctt gaatggtaca gaaattgcca tctctgaatc acaagaacgg atggcggtcg
     6841 tggttcgtcc tgaagatgtg gatgccttcg ttgccgaatg taacaaagaa aatattgatg
     6901 ctgttgtggt ggcgacagta actgaaaaac caaatcttgt catgcactgg aatggtgaga
     6961 caatcgttga cttggagcgt cgtttccttg acaccaatgg tgtgcgcgtg gttgtcgatg
     7021 ccaaagttgt ggacaaggat gtcaaactcc cagaagagcg tcaaacatct gctgaaacac
     7081 tggaatcaga tacccttacg gttctatctg acctcaacca tgcaagtcaa aaaggattac
     7141 agactgtctt tgactgctct gttggacgct caacggttaa tcacccactt ggtggtcgtt
     7201 accaactcac accaactgag gcatctgtgc agaaattgcc agttcaacac ggtgtgactc
     7261 atactgcgtc ggtcattgct caaggtttca acccatatgt agctgaatgg tctccatacc
     7321 acggtgctgc ttatgcggtt atcgaagcaa ctgctcgttt ggtggctgct ggtgccaact
     7381 ggtccaaggc tcgtttctct taccaagagt atttcgagcg tatggataaa caagcagagc
     7441 gtttcggtca gccagtagct gctcttctag gttctattga agcacaaatt cagcttggct
     7501 tgccatctat cggtggtaag gactccatgt ctggtacctt tgaagaattg accgttccgc
     7561 caaccttggt tgcctttggg gtgacgacgg cagatagccg taaggtgctc tctccagaat
     7621 ttaaagctgt tggggaaaat atctactaca tcccaggtca agccctctct gcagagattg
     7681 attttgactt gattaagaaa aattttactc agtttgaagc catccaagct gaccataaag
     7741 tgacatctgc atcagctgtc aaatacggtg gtgtagttga aagtttgact cttgctacct
     7801 ttggaaacta tattggtgca gaggtgacct tgcctgaact taaaacagct ttgacagctc
     7861 aattaggcgg ctttgtcttc acatctcctg aagaaattgc tggagtagag aaggttggac
     7921 aaacgaaagc agactttaca ctgactgtca acggtgtgaa gctaggtgga cacaagcttg
     7981 acagtgcatt tcaagggaca ttggaagaag tttacccaac agaatttacc caagcgaaag
     8041 aactagaaga agtaccagct gtggcatcag atgttgtgat taaagccaaa aaaaaggttg
     8101 aaaaacctgt ggtttacatc ccagtctttc caggaaccaa ctcagaatat gattcagcta
     8161 aggccttcga aaaagaaggt gcagaggtca atttggtgcc attcgtgacc ttgaatgaag
     8221 aagctattgt caagtcagtt gaaactatgg ttgacaatat cgacaagact aatattctct
     8281 tctttgctgg tggattctcg gctgcggatg aaccagatgg ttcagctaag tttatcgtca
     8341 atatcctgct taatgaaaaa gtgcgtgtgg ctattgatag ctttatcgcc cgtggtggtt
     8401 tgattatcgg tatttgtaat ggattccaag ccttagtcaa atcgggtctc ctaccctacg
     8461 gaaactttga agctgctaac agtactagcc caaccctctt ctacaatgat gccaaccaac
     8521 acgtggccaa gatggtggaa actcgcattg ccaataccaa ctcaccatgg ttggctggtg
     8581 tgcaagtggg cgatatccac gctattcctg tttcgcacgg tgaagggaag tttgtcgtga
     8641 cggctgagga atttgcagag ctccgtgaca atggacaaat tttcagccaa tacgttgact
     8701 ttaacggtaa accaagtatg gattctaagt acaatccgaa tggttctgtc catgccatcg
     8761 aaggaattac cagcaagaat ggtcaaatca tcggtaagat gggccactca gaacgttatg
     8821 aggatggtct tttccaaaat atcccaggca ataaagacca acacctgttc gcatcagcgg
     8881 ttaaacattt cactggaaaa taagacttac agattttcta atagatagta tcagtaatgt
     8941 aaaagtcatg taaatctagc tcttgatgat tacaaatgaa aattaggtat aaaaaatgac
     9001 atacgaagta aaatctctta atgaagaatg tggtgttttc ggtatttggg gacatccaga
     9061 tgctgctaag ttgacctatt ttggactcca cagtcttcaa caccgtggtc aggagggggc
     9121 aggaatcctc tccaatgatc aaggacaact gaagcgccat cgtgacatgg ggcttttatc
     9181 agaagttttc agaaatccag ctaatttgga taaattgaca ggagctggtg cgattgggca
     9241 tgtgcgttat gcgactgctg gcgaagcttc tgtagataac atccagccct tcctcttccg
     9301 tttttacgat atgcagtttg gcttggctca taatggaaat ctgaccaatg cagcctctct
     9361 caagaaagaa ctggaacaaa gaggagcaat tttcagcgcg acttcggact ctgaaatctt
     9421 ggctcacctc attcgtcgca gtcataatcc tagcctgatg ggcaaaatca aggaagcgct
     9481 cagccttgtc aaaggtggtt ttgcctatat cttgctgttt gaggacaagt tgattgcggc
     9541 tcttgaccca aatggattcc gaccgctttc gattggtaaa atggctaatg gagcagtagt
     9601 cgtttcctct gaaacctgtg cttttgaggt cattggtgcc gagtggattc gtgatttgaa
     9661 gccaggtgag attgtgatca ttgatgacga gggcattcag tatgacagct atacagatga
     9721 tacccagttg gcgatttgtt ctatggagta tatctacttt gcccgccctg attctaatat
     9781 ccacggtgtc aatgtccata cggcacgtaa gagaatggga gcgcaattgg cgcgagaatt
     9841 taagcatgag gcagatattg tagttggtgt gcccaattct tccctaagcg cggctatggg
     9901 atttgcggaa gaatcaggct taccaaatga aatgggtctg atcaaaaacc aatacaccca
     9961 gcgaactttt atccaaccga ctcaagaatt gcgggagcaa ggagtgcgga tgaaactgtc
    10021 tgctgtttcg ggtgttgtca aaggcaaacg tgtggtcatg gtggatgatt ccattgtacg
    10081 tggaacaact tctcgtcgta tcgttcagct cttgaaagaa gcgggtgcga ctgaggttca
    10141 cgttgccatt ggaagtcctg cactagcgta tccatgtttc tacgggattg atatccagac
    10201 ccgtcaggag ctgattgcag ccaatcatac ggtcgaagaa actcgccaaa tcattggtgc
    10261 ggacagtctg acttatcttt caattgatag cttgattgag tcgattggta tcgaaacaga
    10321 tgcgccgaac ggtggtctct gtgtcgctta ctttgacggt gactacccaa cgcctctcta
    10381 tgactacgaa gaagactatc gtagaagttt ggaagaaaag accagttttt acaagtaggc
    10441 gacagattct ccattaaaga aaaggaaaaa acaaatgaca aataaaaatg catatgccca
    10501 gtcgggtgtg gatgttgaag cgggttatga agttgttgaa cggattaaaa agcacgtggc
    10561 ccgtacggag cgtgcaggtg tcatgggagc tcttggtggc tttggtggta tgtttgacct
    10621 ttccaagact ggggttaaag aacccgtctt gatttcaggg actgacggtg tcggaaccaa
    10681 gctcatgttg gctatcaagt acgacaagca cgataccatc gggcaggact gtgtggccat
    10741 gtgtgtcaac gacatcattg ctgcaggtgc ggaacctctc tattttctcg actacgtagc
    10801 gacagggaag aatgaaccag ctaagctaga acaagtggtt gctggtgtgg cagaaggttg
    10861 tgtgcaggct ggtgctgccc tcatcggtgg ggaaacggct gaaatgccgg gcatgtacgg
    10921 cgaagacgac tatgacttgg ctggttttgc ggtcggtgtg gctgaaaaat ctcaaatcat
    10981 tgacggttca aaggtggtag agggagatgt tcttctcgga cttgcttcaa gtgggattca
    11041 ctcaaatggt tactctttgg ttcgtcgtgt ctttgcggat tacacaggtg aggaagtcct
    11101 accagaattg gaaggcaaga aacttaagga agttctactt gagccgactc gtatctatgt
    11161 caaggctgtc ttgccactca tcaaagaaga gttggtcaac ggcattgccc acatcacagg
    11221 tggtggcttt atcgaaaatg tccctcgtat gtttgcagat gacctagctg ctgaaattga
    11281 tgaaagcaaa gttccagtgc ttccaatttt caaaaccctt gaaaaatacg gtcagattaa
    11341 acacgaagaa atgtttgaaa tcttcaatat gggtgtggga cttatgttgg cggtcagccc
    11401 tgaaaatgta gagcgtgtaa aagaattgtt ggatgaagca gtctatgaaa ttggtcgcat
    11461 cgtcaagaaa gaaaacgaaa gtgtcattat caaatgaaaa aaatagcggt ttttgcctct
    11521 ggtaatggct caaattttca ggtgattgcc gaagaatttc cagtggagtt tgtcttttca
    11581 gaccatcgtg atgcctatgt gcttgagcgt gcaaagcagc tcggcgttct gtcctatgct
    11641 tttgaactca aggagtttga gagcaagaca gactacgaag cagcccttgt cgaactcttg
    11701 gaagaacacc agattgactt ggtttgccta gcaggctaca tgaaaatcgt tggaccaacc
    11761 ttattgtcgg cttatgaagg tcggattgtc aacattcatc cagcctactt gccagaattt
    11821 ccaggagctc atgggattga ggatgcttgg aatgctggcg tgggtcagtc tggtgtgacc
    11881 attcactggg tggattcggg tgtggataca ggccaggtca tcaaacaggt tcgtgtgcca
    11941 cgactagctg atgataccat tgacagattt gaagctcgca tccatgaagc agagtacagg
    12001 ttgtatccgg aagtagtgaa ggctctattt acagattgac tttttgatga ttcatatgat
    12061 atctttgatt ttaaattgga gtcagtgttt gttgaagacg gcttcaaacg gaggtatttg
    12121 taatgttaga atctaaaaaa acaactcgat atgtatttta tgtctatctg atgttattaa
    12181 cttggggaat cttatttaag tttgaaacaa atcctgaatt tatagcattt ttcttagctc
    12241 caaggtatat caattggatt ccattttcag aaccactaat agtcgatgga aaaattgttt
    12301 ttgctgaaat gttatttaat ctgatttcct ttattccatt aggtgtttgt ttccctttga
    12361 taaaaactaa tttatctagt ttaagaatag tcgggacagg tttcttgatt agtttattgt
    12421 ttgagtgctt acagtatatt ttagcaatag gtataacaga tataacggat ttgactttaa
    12481 atacgctagg tgtccgtgta ggcttactga tttatcaaat ttttataaga gtgttcaaat
    12541 cacagactag aaaatggatc aatatcttag gtatgcttag ccttggtttt gcttatcttg
    12601 ttttactgtt actgcattta attggtgttt aactaatgat taaaaaggag aatataatga
    12661 ctaaacgcgt cttaatcagc gtctcagaca aagcgggcat tgttgaattt gcccaagaac
    12721 tcaaaaaact tggttgggag attatctcaa caggtggaac taaggttgcc cttgataatg
    12781 ctggggtgga taccattgct atcgatgatg tgactggttt cccagaaatg atggacggtc
    12841 gtgtgaagac cctccaccca aatatccacg gagggcttct cgctcgtcgt gacttggata
    12901 gccacttgga agcgggtaag gacaacaaga ttgagctcat tgaccttgtg gtggtcaacc
    12961 tttacccatt taaggaaact atccttaaac cagatgtgac ttatgctgat gcagttgaaa
    13021 atatcgatat tggtgggcca tctatgcttc gttcagcagc gaaaaatcat gccagtgtta
    13081 cagttgtggt agatcctgct gactacgctg tggttttgga cgaattggca gcaaacggcg
    13141 aaacctctta tgaaactcgc caacgtttag cagccaaagt atttcgtcac acagcggctt
    13201 atgacgcctt gattgcagaa tacttcacag ctcaagtggg tgaaagcaag cctgaaaaac
    13261 tcactttgac ttatgacctc aagcaaccaa tgcgttacgg tgagaatcct caacaagacg
    13321 cggactttta ccagaaagct ttgcctacag actactccat tgcttcagcc aaacagctca
    13381 acgggaaaga attgtcattt aataatatcc gtgatgcaga tgctgctatc cgtatcatcc
    13441 gtgacttcaa agatagtcca accgttgtgg ctctcaaaca catgaatcca tgtggaattg
    13501 gtcaagctga tgacatcgag actgcttggg actacgctta tgagtctgac ccagtgtcta
    13561 tctttggtgg gattgtcgtc ctcaaccgtg aggtggatgc tgcgacagct gagaagatgc
    13621 acggcgtttt cctcgaaatc atcattgcac caagctatac ggatgaagcg ctagccattt
    13681 tgatcaataa aaagaaaaac ttgcgtatcc ttgccttgcc atttaatgct caagaggcta
    13741 gcgaagtgga agcagaatac acaggtgtag tcggtggact tctcgtgcaa aatcaagacg
    13801 tggtcaagga aagcccagct gactggcaag tggtgactaa acgtcagcca actgagacag
    13861 aagcgactgc tcttgagttc gcttggaagg ctatcaagta cgtcaaatca aatggtatta
    13921 tcgtgaccaa cgaccacatg acacttggtg ttggtccagg tcaaaccaac cgtgtggctt
    13981 ctgttcgcct tgccattgac caagccaaag atcgtctgga cggggcggtc cttgcttcag
    14041 atgccttctt cccatttgcg gataacgtgg aagaaatcgc caaagcagga attaaggcca
    14101 tcatccagcc cggtggctct gtccgtgacc aagaatctat cgaagcggca gacaaatatg
    14161 gcttgaccat ggtctttaca ggtgtgagac attttagaca ttaagaagat aaaagggaag
    14221 aaaacagttt ctttcctttt ttggcttaaa atgctaactg aaacaagatt aaaacgaact
    14281 ttttttgata taatgttggt aaataattcg caaaagaggt tgaggaatga aactgcttgt
    14341 tgtcggttct ggtggtcgtg agcatgcgat tgctaaaaag ttacttgaat caaaagacgt
    14401 gaaaaaagtc tttgtagctc ctgggaatga tgggatgact ctggatggtt tggaattggt
    14461 aaatatctct atttccgaac attctaaatt gattgacttc gcaaagacca atgatgttgc
    14521 ttggaccttt atcggtccag atgatgccct tgctgctggt atcgtggatg attttaacca
    14581 agctgggctt aaggcctttg gtccgactag ggctgcagcg gagctggagt ggtccaagga
    14641 tttcgccaag gaaatcatgg tcaaatatgg tgtttcgaca gcagcctatg gcacattttc
    14701 agatttcgag gaagcaaagg cctatatcga aaagcatggt gcgcctatcg tagtcaaggc
    14761 ggatggcttg gcgcttggga agggtgtcgt cgttgctgag acggttgagc aagcggtcga
    14821 agccgctcat gagatgcttt tggacaataa atttggtgac tcaggtgcgc gcgtggttat
    14881 tgaggaattc cttgaaggag aggaattttc actctttgcc tttgtcaatg gtgataagtt
    14941 ctacatcatg ccaacggctc aggaccacaa acgtgcctac gatggcgaca aagggcctaa
    15001 cacgggtggt atgggtgcct atgcgccagt tccacactta ccacagagtg tagttgatac
    15061 agcggttgac accattgtca agccagttct agaagggatg attaaagaag gtcgccctta
    15121 tctgggagtt ctttacgcag ggcttatcct gacagctgat ggaccgaaag tcattgagtt
    15181 caacgctcgg ttcggagatc cagaaactca gattatcttg cctcgcttga cctctgactt
    15241 tgctcaaaat atcacagata tcctggatag caaggagcca aatatcatgt ggacggacaa
    15301 gggtgtgact ctgggtgtgg ttgtcgcatc caagggctac ccgctagact atgaaagggg
    15361 cgttgagttg ccagccaaga cagaaggcga tgtcatcacc tactatgcag gggctaagtt
    15421 tgcggaaaat agcagagcac tgctctcaaa cggcggacga gtttatatgc tggttaccac
    15481 agcagatacc gtcaaagaag cccaagccag catctaccaa gaactatccc aacaaaaaat
    15541 agaaggactc ttctaccgaa cagatatcgg aagcaaggca attaagtaaa gatataagaa
    15601 taacgcgccg tagtcgccaa acacgataat ggtcgtcgtg gtgaaaagac cagaacagtg
    15661 aatgttctgg tcagggggaa acttggagac cgtaggctca aagtttagga atgaaaccga
    15721 aggtttgctt ccgcctccat cacctaagac cattatcaaa aagaaaaata aaaattcaca
    15781 aaatacgtta atgatcgtat ggtttgcgag cgttaacgag ctaatataga acaatcaccg
    15841 ccgttgtgaa agaacgattg gatgataatc caatcgttca gggaaattgg aagaccttgg
    15901 gtttccaatt taggcatgag acacctttgg tggctgctgc cgtccctcac aagctaaggt
    15961 gattgttgaa aaagaggaaa aaggagaaga aatgaaacca gtaatttcca tcatcatggg
    16021 ctcaaaatcc gactgggcaa ccatgcaaaa aacagcagaa gtcctagacc gcttcggtgt
    16081 agcctacgaa aagaaagttg tttccgccca ccgtacacca gacctcatgt tcaaacatgc
    16141 agaagaagcc cgtagccgtg gcatcaagat catcatcgca ggtgctggtg gcgcagccca
    16201 tttgccaggt atggtcgctg ctaaaacaat ccttccagtc attggtgtac ctgtcaagtc
    16261 tcgtgctctt agtggagtgg attcactcta ttctatcgtt cagatgccgg gtggggtgcc
    16321 tgttgcgacc atggctatag gtgaagctgg agcgactaac gcagctctct ttgccctccg
    16381 tctcctctct gtagaagata agtccattgc ggatgcactt gccaactttg ctgaagaaca
    16441 aggaaaaatc gcagaggagt cgtcaaatga gctcatctaa aacaatcgga attatcggtg
    16501 gcggtcaact gggtcagatg atggccattt ctgctatcta catgggccac aaggttatcg
    16561 cgctggatcc tgcggcggat tgcccggcct ctcgcgtggc ggaaatcatt gtggcacctt
    16621 ataacgatgt ggacgccctc cgtcagttgg cagaccgttg cgatgtcctc acttacgagt
    16681 ttgaaaatgt cgacgctgac ggtttggatg ccgttatcaa ggatggacaa ctccctcaag
    16741 gaacagatct gctccgcatt tcgcaaaatc gtatttttga aaaggacttt ttgtcaaaca
    16801 aggctcaagt cactgtggca ccctacaagg tcgtgacttc tagcctagac ttggcagata
    16861 tcgacttgtc gaaaaactat gtcctcaaga ctgcgactgg tggctacgat ggtcatggac
    16921 aaaaggttat tcgttcagaa gcagacttgg aagcagccta tgcgctagca gactcagcag
    16981 actgcgtctt ggaagaattt gtcaactttg accttgagat ttctgtcatc gtgtcaggaa
    17041 atggcaagga ggtgacgttt ttcccagttc aggaaaatat ccaccgcaac aatatcctgt
    17101 ctaagaccat cgtaccagcc cgcatttctg aaagtctagt agacaaggct aaagctatgg
    17161 cagtgcgaat cgcagaacaa ctcaacttgt ctggaactct ctgtgtggaa atgtttgcga
    17221 ctgatgatga cgttattgtc aatgaaatcg ccccacgacc acataactct gggcactatt
    17281 ctattgaagc ctgtgatttc tctcagtttg acacccatat tctcggtgtt ctcggagcac
    17341 cattaccagt catcaaactc catgcgccag ccgttatgct taatgtcctc ggtcagcatg
    17401 tcgaggctgc tgagcaatat gtgacagaaa attcaagcgc ccacctccac atgtatggta
    17461 aaatagaagc gaagcacaac cgcaagatgg gacatgtgac cttgtttagt gatgtaccgg
    17521 atagtgtgga tgagcttggg gaagggattg atttttagga caagtctatg atacaaatta
    17581 tcgttaatac atttattgaa aaggataaga ctggagcagt tgttgaagtg ttgtatgcca
    17641 gtgctgacca agataaggta caagctaaat atgaagaact agctgcataa taccccgaaa
    17701 attatttagc tatctatgat gtaccgctgg atacggattt gaatacacta gatcattacc
    17761 cgtctgtgtt tattgaaaaa gaggagtttg agtagaaatc ttggtttacc tagatagctt
    17821 attcccaaca gcttaagaag aaaggaaaaa ttaacacatg atcaaccgtt actctcgccc
    17881 tgagatggcg aatatttgga gtgaagaaaa taaataccgt gcttggcttg aggtggaaat
    17941 cctctctgac gaggcatggg ctgagttggg ggaaatccct aaggaagatg tggctttgat
    18001 tcgcaagaag gcggactttg acatcgaccg tattttggaa attgagcagg agacgcgcca
    18061 cgatgtggtg gctttcacgc gtgcggtttc tgagactctt ggtgaagagc gcaagtgggt
    18121 tcactatggg ttaacttcta ccgacgtggt ggatactgct tatggttacc tctacaagca
    18181 ggccaacgac atcatccgtc gtgaccttga aaacttcact aatatcatcg ctgacaaggc
    18241 caaggagcac aagttcacca tcatgatggg gcgtactcat ggtgtgcacg ctgagccgac
    18301 aacctttggt cttaaattgg caacttggta cagcgaaatg aaacgcaata tcgagcgttt
    18361 cgagcatgca gctgctggtg tagaagctgg taagatttct ggtgcggttg ggaactttgc
    18421 caatatccca ccatttgtag aggagtatgt ctgcgataaa cttggcatcc gtgcccaaga
    18481 aatctctaca caagtccttc ctcgtgacct tcacgctgag tactttgcgg ttcttgccag
    18541 cattgcgact tcaatcgaac gtatggcgac tgagattcgt ggtctacaaa aatctgagca
    18601 acgcgaagta gaagagttct ttgctaaagg gcaaaaaggg tcttcagcaa tgcctcacaa
    18661 acgcaaccca atcggttctg aaaatatgac tggtctggcg cgtgtcattc gtggtcacat
    18721 gattacggct tatgaaaacg tcgctctctg gcacgaacgc gatatttccc actcatcagc
    18781 tgagcgtatc atcacaccag atacgaccat tttgattgac tacatgctca accgttttgg
    18841 aaatatcgtt aagaacttga cagtcttccc agaaaatatg atccgaaaca tgaactcgac
    18901 ttttggtctt atctttagcc aacgggctat gttgacattg attgaaaaag gcatgacccg
    18961 tgagcaagcc tatgacttgg tgcaaccaaa aacagcctac tcttgggaca accaagtaga
    19021 ctttaaacca cttcttgagg cagattcaga agtaacatca cgtctcacac aagaagaaat
    19081 cgatgaaatc ttcaacccag tttattacac caaacgagtg gatgatatct ttgaacgtct
    19141 tggactaggt gattaattaa aaaataaaca gcgagcttca atctcgctgt ttatttttta
    19201 tcgaaaagac ttagtcttct tttcttttag tgagtccata ggctgctagt gtggacatga
    19261 gtcctgcgac tactagtcct gcagaatcgt gagttcctgt ttcaggaagt tttttctctg
    19321 ttaccacagg agctggatct tgaggaagag ctttgctttc ctcagcagga gcagttgatg
    19381 gagctggttg gcttaggatt tctagttttg gtttttcttc agcaatagcg gcttgtccgt
    19441 tttcatcgcc tacatgtgtt accatagttc cgacttcgac tatttgagta acggcttcct
    19501 gtgctacgac actatttaca agtgttttca cttccttacc atcggcagaa gtgctcacag
    19561 agtagaagtt gctacgatgt ccattgacgc ccttagtaat gacttgtgtt tttcctttga
    19621 gtaagagtgg attttcacga gtcactgtgg taaatggaat ttcttctttt tggatatcca
    19681 gtctaggttt tacctcagta gttggtgcaa gaccactttc atcacccttg tgagttacag
    19741 gagcgccaac ttcaaccact tggtttataa cttctttggt tacctggcta tcaaggactg
    19801 tttctgttgt ttttccattt tcagtgagta cagagatgta atgagttcgt tcacctttga
    19861 ctcctgctgt gataatattt tcctgaccag ctgggaggtt aggattttct ttcttgataa
    19921 cttcaaatgg aatttcttca gttcttgtga tgagttctgg tctggtttca acattggcag
    19981 ccacttcatt ttcatctagg cttcttgaat gagttgcagc tggtttgagg ccttgaagag
    20041 cggcttttag gttggctaca agtgtgtcaa gctcagcttg tttattacgg ttgaggttgt
    20101 aatttagagc tgttttagct gcgtcaaggg cctcaagact ttctttacta tatccttcta
    20161 agtttgtagg aattttagct aattcttcgc ggagagcatt ataattagca cggaagtagt
    20221 ctttgttgtg gtctgcaaag gcagtcatga gttcaaagat ttcctcttcc ttgtattcag
    20281 cgcttggtct atctgcccag attgaaagca tacttccgac tgttggaaga tctacttcag
    20341 gatatttggt agaagctagt tgattgaatg gaactttacc agaattttca actgcttttg
    20401 aaagagggta agcttcctct tgtttgtgat tgcctataac ataataccag tcaccgttgg
    20461 tattcaagaa tttatagcct ttgcttgcta ggtattgagg tgatgcgagg ttatatcccc
    20521 accagccttt agaccagtaa gaaatcaaga catctttgtc aaactgaaca tcgtccttgt
    20581 cttcatagta gaagccatcg ttgaaggcca ttggttgaag ccctctttct ttggccatag
    20641 ctgcgagggt gttggcatat tcggcaaatt tgccatagag ttgataccac ttgaggtagt
    20701 accagccttg ggcactagtc gcatcgttgg cgtattcgtc agtaccaaag ttgaaaatct
    20761 ttgttttacc tgcaaagaag tccatgtatt taccgatgag ggcttttaca aagtccatcg
    20821 cttcttcgtt tttcaagtcc atagttgttt ttgaaacttt atcaaagtgg gcttgaggat
    20881 ttttaatacc taatttttcc atggcaacca gcatagcatc catgtgacct ggactgttaa
    20941 tagctgggat gagaccgatg tccttagatt tagcgtattc aattagctct gtcacttctg
    21001 cctgtgttag tgcagtaccg tttggatcgt cgtagtaagc tttagttcct tcgataatag
    21061 cttttttaac gtcatcacta gcataggttt ttccgttggc agtaatggtc atatcattga
    21121 gtagaaagcg aagtccgtca tttcctagaa ggagatggac atcagaatat ccgagctcac
    21181 tggccttgtc tacgatgcgt ttgagctggt tcagagtaaa gtatttgcgt ccagcatcga
    21241 ttgagattac cttgtttttg gcaagttttt caacctcacg tttagcttct tcttcttttt
    21301 gagcttcagg cgtgagggtc aagttgttga cagtttcttg aagtttagca atggcttgat
    21361 caatcgtatc ttgttgggca cggctaaggt tgctatcgag agagcgaata gctttttcag
    21421 cttcttttac ggccgcgacg ctttctgcag tataacggtt caggtctttt ggtacctcgt
    21481 taagtgcttg ctctgcagat tcataatcag ctgcgaagta ttcagcgttg gcatttgcaa
    21541 aatgacgcat gagtttgaag aggcgtgatg gtgaataacg tgcagatgga gtgtcagccc
    21601 aagcagctac cataccaccg atgattggga tatcagctcc ttctgttttt ggtacagaag
    21661 tgattggtgt gtttttaata ccattgagcc cctgatcgag attgtaccag ccttggccat
    21721 cagcgtttcg tccaagaacg tagtaccaag catcattggt attaaggatt tggtgacctt
    21781 tttcagctag tagtttagaa gaagcgacat cgtagcctcc ccaaccacca gtccacatag
    21841 aaacgatgat gtctttgtca aaactaccaa agcttgtgtc gctattgtag tagataccgt
    21901 cgttaaaggc cattggtttg agaccgtgcg attttacaat acgagcgagg tcattggcgt
    21961 aggcaataaa tttttcatag ccttttacag ggtagccttc gtttggatag tatttatcag
    22021 cttgaagcac actccaacct ttagcatctg tcgcatcatt ggcatattca tcaagtccga
    22081 tgttgaagat ttcagtcttt ttcgcgaaat aagcagcata cttgtcgata agggcttttg
    22141 taaaagcgac agcttgttcg ttgtcaagat cgacagtacg ggctgatttc ttcccaaaat
    22201 agctaaagtt agggttttgg attcccaatt ctttcatggc attgagaatc gcatccatgt
    22261 gtccaggact atttactgtc ggaatgagac cgataccttt atctttggca tagttaatca
    22321 gatctgtcat ttgactttct gttaagtgat tgccgtttgg atcgttgtaa taatcatttg
    22381 tacctttttc aatggcgcgt ttgacatcgt cactggcata ggtcttgccg ttagctgtga
    22441 tgctcatatc gtccaacatg aaacggagtc catcatttcc gactaatagg tgtaaatcag
    22501 tgtagccata atgtttcgct ttatcgatga tttccttgag ctgttctggt gagaaatatt
    22561 tacgtccagc atcaatagaa acaattttct ttttcgctag tttttcattt acagttgcag
    22621 cacgttcctt tcctgcctct gtttccggtt tgtcagcctc tgctttcgct tcatcttttt
    22681 tagctggttt atccttgtca gtcttgtctg tatttgactc tttagaatca acctctttcg
    22741 cttcttcctt tttagggcta gcttcttctg cctttttatt agcagtttct ttttcagcag
    22801 aagttggagt taccacttct gctttatcac taggagttga actaacttcc tcttgtggtt
    22861 tttcttctgt ttttggaaga ctagctacct tatcagtagc tggagtttct gtttctacag
    22921 tttttggagc ttctggttga agctctgctt taggtgtttc ctcagtccga ttttcggatg
    22981 attgagggga atcagaaacc gtatggatgg tcggttggtt ttctgtagta gtaggagtaa
    23041 ctccatcggc tgcaacagtc tgtgcttgga aggcaaatcc aattagaaca gaagctgctc
    23101 ctacagcgta tttacgaata gaaaaacgct gttgtttttc atgtttcatt gcaaaacctc
    23161 ctgattgcat tgttatattg atagcgatta tataaatcaa cgcctttatt ttatttctta
    23221 tattaacgag agtcaagagg agatgacaaa aaactataat aagtataaaa aaatataaaa
    23281 tttaaactta agatttcag
//
LOCUS       DAVLZS010000031        22436 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLZS010000031 DAVLZS010000000
VERSION     DAVLZS010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22436
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.031"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(6..203)
                     /gene="blpI"
                     /locus_tag="VYO88_001325"
     CDS             complement(6..203)
                     /gene="blpI"
                     /locus_tag="VYO88_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV1719414.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            485..1072
                     /locus_tag="VYO88_001326"
     CDS             485..1072
                     /locus_tag="VYO88_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1719415.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            999..2642
                     /locus_tag="VYO88_001327"
     CDS             999..2642
                     /locus_tag="VYO88_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1719416.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2653..4014
                     /locus_tag="VYO88_001328"
     CDS             2653..4014
                     /locus_tag="VYO88_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV1719417.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDTIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4071..4226
                     /gene="blpC"
                     /locus_tag="VYO88_001329"
     CDS             4071..4226
                     /gene="blpC"
                     /locus_tag="VYO88_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1719418.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(4270..5610)
                     /locus_tag="VYO88_001330"
     CDS             complement(4270..5610)
                     /locus_tag="VYO88_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1719419.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(5624..6361)
                     /locus_tag="VYO88_001331"
     CDS             complement(5624..6361)
                     /locus_tag="VYO88_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719420.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6366..6704)
                     /locus_tag="VYO88_001332"
     CDS             complement(6366..6704)
                     /locus_tag="VYO88_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719421.1"
                     /translation="MKYMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6980..7309
                     /locus_tag="VYO88_001333"
     CDS             6980..7309
                     /locus_tag="VYO88_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1719422.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7483..8532)
                     /locus_tag="VYO88_001334"
     CDS             complement(7483..8532)
                     /locus_tag="VYO88_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1719423.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVSGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8529..9260)
                     /locus_tag="VYO88_001335"
     CDS             complement(8529..9260)
                     /locus_tag="VYO88_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719424.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9328..9738
                     /locus_tag="VYO88_001336"
     CDS             9328..9738
                     /locus_tag="VYO88_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1719425.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9748..10035
                     /locus_tag="VYO88_001337"
     CDS             9748..10035
                     /locus_tag="VYO88_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719426.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10197..10436
                     /locus_tag="VYO88_001338"
     CDS             10197..10436
                     /locus_tag="VYO88_001338"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719427.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(10770..11906)
                     /gene="dnaJ"
                     /locus_tag="VYO88_001339"
     CDS             complement(10770..11906)
                     /gene="dnaJ"
                     /locus_tag="VYO88_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1719428.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12308..12664)
                     /locus_tag="VYO88_001340"
     CDS             complement(12308..12664)
                     /locus_tag="VYO88_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV1719429.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12666..14489)
                     /gene="dnaK"
                     /locus_tag="VYO88_001341"
     CDS             complement(12666..14489)
                     /gene="dnaK"
                     /locus_tag="VYO88_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1719430.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14958..15482)
                     /gene="grpE"
                     /locus_tag="VYO88_001342"
     CDS             complement(14958..15482)
                     /gene="grpE"
                     /locus_tag="VYO88_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1719431.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15509..16543)
                     /gene="hrcA"
                     /locus_tag="VYO88_001343"
     CDS             complement(15509..16543)
                     /gene="hrcA"
                     /locus_tag="VYO88_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1719432.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16707..17216)
                     /locus_tag="VYO88_001344"
     CDS             complement(16707..17216)
                     /locus_tag="VYO88_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV1719433.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSLFREELSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17824..20157
                     /locus_tag="VYO88_001345"
     CDS             17824..20157
                     /locus_tag="VYO88_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1719434.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20170..21633
                     /locus_tag="VYO88_001346"
     CDS             20170..21633
                     /locus_tag="VYO88_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1719435.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVCDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCDFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21633..>22436
                     /locus_tag="VYO88_001347"
     CDS             21633..>22436
                     /locus_tag="VYO88_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1719436.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLAEQQRIIEAIESALEKVDEYAESYNRLEQLDK"
BASE COUNT         7140 a         4533 c         4141 g         6622 t
ORIGIN      
        1 taatcttaca aagaggacat aattcctgaa cctacacaaa taagtgttgc tgctccccca
       61 gttatcggac cagtcgcagc agctaatagt actgctccaa tacaaccacc gattgcagat
      121 cctaaattgc ctcttcctcc actaactatt tcgagttctt cattatccat aacagaaaat
      181 tgttccatca tttttgtatt catgacaaat actccttttt tcttttttta tttttgtctt
      241 gttgtaactt tgataagttt agtatatcat cgttttttaa aatttttcat ccagatcttg
      301 aattgtcatc gaaacgtctt gaattagctt ttttatttca agccacctct aaatgtttaa
      361 aaaaaataat ttctaatcac ttttttacca ttcaggaagt tttaatgact attcaagatt
      421 tcataaaata tgaacttagt tttatgacat aatagaccta tccactatat gaaaggaatt
      481 gccaatgact tcttataaac gtacatttgt tcctcaaata gatgcgagag actgtggtgt
      541 cgctgcctta gcctcgattg ctaaattcta tggttcagat ttttctctag ctcacttgag
      601 agaacttgca aagaccaata aagaagggac gactgctctt ggcattgtaa aagccgctga
      661 tgaaatgggc tttgaaacaa gacctgttca agcagataaa acgctctttg acatgagtga
      721 tgtcccctat ccatttatcg ttcacgttaa caaagaagga aaactccaac attactatgt
      781 tgtctatcaa acaaagaaag actatctgat tattggtgat cctgaccctt ctgtaaaaat
      841 cactaaaatg tcaaaagaac gctttttcta tgaatggact ggagtagcta tttttctagc
      901 taccaaaccc agctatcaac cccataaaga taaaaagaat ggtctactaa gcaagcttcc
      961 ttcctctgat tttcaaacaa aaatctctca ttgcttacat tgttctctca agcttattgg
     1021 tcactattat caatataggt ggttcttact atctccaagg aatcttggat gaatacattc
     1081 caaatcagat gaaatcaact ttaggaatca tctcagttgg tctggttatc acctatatcc
     1141 tccaacaagt catgagcttc tccagagatt atctcctaac cgttctgagt cagagattaa
     1201 gtattgatgt gattttatcc tatattcgcc atatttttga acttcccatg tctttctttg
     1261 cgacacgtcg tacaggagaa atcatttcac gattcacaga tgctaactct attatagatg
     1321 ccttggcttc taccattctt tctctttttc tggatgtttc tattctgatt cttgtaggag
     1381 gcgtcttact agcacaaaac cctaatctct tccttctttc tcttatttcc attcctatat
     1441 acatgttcat catcttttct tttatgaaac ctttcgaaaa aatgaaccat gatgtcatgc
     1501 aaagtaattc tatggttagc tctgccatta tcgaagatat caacgggatt gaaactataa
     1561 agtcgctcac gagtgaagaa aatcgctatc aaaatataga cagcgaattt gtagattatt
     1621 tggaaaaatc ctttaagctc agtaaatatt ctattttaca aacgagttta aagcagggaa
     1681 caaaattagt tctgaatatc cttatcctat ggtttggcgc tcaattagtc atgtcaagta
     1741 aaatttctat cggtcagctg attaccttta acacactttt ttcttacttt acaactccta
     1801 tggaaaatat tatcaacctc caaaccaaac tccaatctgc gaaggtcgct aataaccgtt
     1861 tgaacgaagt ctatctagtc gaatctgaat ttcaagttca agaaaaccct gttcattcac
     1921 attttttgat gggcgatatt gaatttgatg acctttctta taagtatggt tttggacgag
     1981 ataccttaac agatattaat ctcacgatta aacaaggaga taaggttagc ctagttggag
     2041 ttagtggttc tggtaaaaca actttagcca aaatgattgt caatttcttt gaaccctaca
     2101 aagggcatat ttccatcaat catcaggata ttaaaaacat tgataaaaaa gtcttgcgcc
     2161 gtcatattaa ttacctaccc caacaagcct atatctttaa tggctctatc ttggaaaatt
     2221 taaccttggg cggtaatcat atgattagcc aagaagatat tctaagagct tgtgaattag
     2281 ctgaaatccg tcaagacatt gaaagaatgc ctatgggcta tcaaactcag ctctctgatg
     2341 gagctggtct atcaggagga cagaagcaac gaatagccct cgctcgtgct cttttaacta
     2401 aatctcctgt tttaatacta gacgaagcta ctagcggtct tgatgtcttg actgagaaaa
     2461 aagttataga taatcttatg tccctaactg ataaaaccat tctctttgta gcccatcgtc
     2521 tcagtatagc cgaacgaact aaccgtgtca ttgttcttga ccaggggaaa atcattgaag
     2581 ttggtagtca ccaagagtta atgcaggcgc aaggcttcta ccatcatctg ttcaataaat
     2641 aaggagaatg tcatgaatcc taatcttttt agaagcgtcg agttttatca gagacgttac
     2701 cataactatg cgacagtatt aatcatacct ctttcattat tatttacttt catcttgatt
     2761 ttctcccttg ttgccacaaa agaaattact gttacttccc aaggggaaat cacccctaca
     2821 agtgtcattg catctattca gtcgaccagt gataatccta tccttgctaa tcatttagtg
     2881 gcaaatcaag tagttgagaa aggtgactta ctcatcaaat actctgaaac aatggaagag
     2941 agtcagaaaa ctgccttaga aactcaatta caaagacttg agaagcaaaa agaaggactt
     3001 ggaatcttga aacaaagctt ggaaaaagcg actgatcttt tttctagcga ggatgagttt
     3061 ggctaccata atacttttat gaattttact aaacaatccc atgatattga actgggtatc
     3121 tcaaagacta acactgaagt ttcaaatcaa gctaatctta ccaatagcag ttcatcagcc
     3181 atcgaacaag aaattacaaa agttcaacaa caaattggag aatatcaaga gctgagagat
     3241 actatcgtaa ataaaagagc tcgcttacca actggcaatc cgcaccagtc aattttaaat
     3301 cgttatctta tagcctctca agaacaaaca caaggaacgg cagaggagcc atttttatct
     3361 caaattaatc aaagtattgc aggtctggaa tcatctatcg caagcctcaa aattcagcaa
     3421 gctggtatcg gaagtgtagc aacttatgat aatagtttag caaccaaaat tgaagtactc
     3481 cgcactcagt ttttacaaac agcctcacag caacaactaa ccgtggagaa tcaattaaca
     3541 gaattaaaag tacaactaga tcaagcaacg cagcgcttag gaaacaatac cttaaccgct
     3601 ccaagtaaag gtatcgttca tctgaacagc gaatttgaag gtaaaaatag aattccaact
     3661 ggtacagaaa ttgctcaaat attccctgtc atcacagata caagagaagt actaatcact
     3721 tactacgtat cttctgacta tctacctcta ctagataaag gacaaactgt aagattaaaa
     3781 ctggagaaga ttggaaatca cggcaccacc atcatcggcc aacttcagac aattgatcaa
     3841 actcctacca gaacagagca aggaaatctc tttaaattaa ccgctcttgc aaaactatct
     3901 aacgaggata gtaaactcat ccaatatggc ttacaaggtc gcgtcactag tgtaactaca
     3961 aagaaaacat attttgatta tttcaaagat aaaattttaa cccattctga ttaattttca
     4021 gataacactc tataactatt tattatctta tcaaaaagga gaatcataac atggataaga
     4081 aacaaaacct aacttcattt caagaactaa caactaccga actcaaccaa attataggtg
     4141 gaggatggtg ggaagatttc ttatatagat ttaatataat tgaacaaaaa aatacaaaag
     4201 gatttcatca gccaatacaa ctataaaaaa acaagaccaa gagaacgcac tctcggtctt
     4261 attttttctt cattctatat gtattacagt aagtacctga cgaaaaacgt gatcttggca
     4321 ggtggtattg agactggtat tgggatgact ttccacaatt ttcataacgg tatagagacc
     4381 aactcctctc tcctcccctt tagaacttgc tccaaaggag aagatttcag aaatatcgat
     4441 tccctcttct ttgatggaat tttcaatgat aaaggtctcc tgtgctccat ttttaaaaaa
     4501 ggcaattgaa acatgaggtt gacaggcttc tacactagct tcaatagcgt tgtcacaaag
     4561 gatagacaca acggttagaa aatcaagtag actcatcccc tctacctgaa tctcctctgg
     4621 aacttcgaca ttaaagacaa tgttcttatc tctagctttt ataaattttc cagctaggag
     4681 acttttgagg gcacgatccc gaacattcac caatcggcca aggtcatatt tattgtcctg
     4741 caatttttca ctagaatcct ttaagaccga gtcgtagatc tcttttatct gctccatatc
     4801 ctcctcttca atgcccagac gtaagctagt caagaggttg gtgtagtcat ggcgaaaact
     4861 ccgtacttcc ttataaagct cctctatatg ccgactatac cgctccatct ctctgtagcg
     4921 caagtcctgc tcttggttca gtctctcatg gagtttgtcc ttcaaatagg tatccaattt
     4981 cttgataatc cccataaaaa agagcaggta aaagactagg atgagatggc gaacagtcgt
     5041 tgattgaatc ccctgttcat attcaaagta agacagattt tgtatcacca aatagtaagc
     5101 ccccattatc cagttaatct gagtcaggga cttttgaaaa tctttatcga gaatcccctt
     5161 tctcaagcta gtgaaatcat agtccaacca tttcaaaaaa gctagagaaa tgaagaaatt
     5221 gaaaattatt atacataacc aaataaatga gtagtcatca tatacttgcc cttgtcccaa
     5281 aaatggaagc acaaaatagg aaacacctct ataaaagaga ttcactaata tcattggaaa
     5341 gagaccataa aagagaagga gttttttagg aagttctctt aacaataaga aagataagcc
     5401 tatgccgtac aagggttcca taaaataaga taggtaaaca tttcctacca tatagccaag
     5461 cattccaaaa acaacggcca acagtatctt aaaaagaaag gccttaaaaa tcctctcaaa
     5521 agtgagacta attccatcta ccttaaagaa tatgacaatt tttaatccgt gagtaacaag
     5581 tgtatacaac aatatccaag caacattcat aaactctcct agctcagtgt aagttattaa
     5641 tagcctcaga cacttccctg accttataac gcgcgattag acaacttcca ccattgggaa
     5701 agaaaagcag tttttctttc ttatctaaat gcaccacatt ggcaggattg atgagaaaag
     5761 agcgatggca ctgcaagaga cgaggctcct gcttgagaac ctcctctaga ctcgctgtaa
     5821 attccagcct gtctgtcttg gtatagagaa taacacgatg gggtcttgtg gacgtttcga
     5881 gatagtaaac ctctttaaaa ggatactgga attgagcaaa ttttgattta aagtaaaagc
     5941 aatcttccgc tagactttta ctgtcttgac cattggcata gaggagggct gtctcgatac
     6001 gagattcaaa ctcctctgcc gaaagggcct tatcaatata gtccagagca gacacttggt
     6061 agcgaaagga caggggcata aactccgagt gagtcgtcac aaagacgatt agggcatatg
     6121 ggtcttgttc ccgaatcttt ctagccactt ccagtccctt catctcttca tttcgaatct
     6181 caatatccaa aaagaatagc tgatgggccc ccttctcatg cacctctgcc agcagttggt
     6241 ccggcttgcc aaatacctca aaagagctag gaatgatatg atgtgctttc aaaagtttct
     6301 caatcgtcgt ttcaattcta gtctgttggg aaaaatcatc ttctaaaaca aatattctca
     6361 tcttcttact ctccctcttt caaccatttt tgacgtattt ctctatagcg acgtctggca
     6421 tacttgacag catattgacc ttcttctccg agaaaaagga ttctttcttg aaaatcaatc
     6481 gattttaatt tatcaagatt aaccaaacaa tttcgatgac atctcatcaa agtttcccca
     6541 tattggttct caagattact taaattttga agcatattaa aactagcttc ttctgtaaca
     6601 atctgtacgg tatgggcttt agttggatgt gtttggatat agtagatatc gtcgacgttt
     6661 actttataga ctgttttctg cgtctgaata atcatatatt tcattggatt ctcctcctaa
     6721 gaaaagaata acagaaaagt tctagcccaa gcccacccaa tcctaaacag tctttgaaag
     6781 ctcctaaaag gattattttc tacaacatca tgatgagctt acaactattt tatcataaaa
     6841 ttcactcagc gcaattcaag acatttcaat gacaattaaa gatttgaata aaaaaaaaga
     6901 attaaaagtg ataaactaac agtatcaaaa cacagttgcc agaagtaaga ctggcaccca
     6961 gattaaagga ggcattccca tgacagatac agaccccatc aaaagagctc atactttgat
     7021 tactgactta aacaaagcct accaagcatg caaacaggca agcgctgacg acgtccgctt
     7081 tcaggagcaa ttaaactcta ttcttggttt tctagccaag gctgaaacag tggataatcg
     7141 attcttgatt gaactagaaa aattttacca gacttccagt cttctcatgg gactcagcgc
     7201 tcttgatcca gatgctccaa ctcgcgccgc ttggcgggcc tatgaccgct tccactttga
     7261 ccaagtcaag accaagttaa tactcaatga aaatcaaaga gcaaactagg aagctagccg
     7321 caagctgtac ttgagtacgg taaggcgacg ctgacgctga cgtggtttga agagattttc
     7381 gaagagtata agtctctacg gatcaaccat tatcctgtag taacaaaaaa gaagctgaga
     7441 cagactgaac tcaacttctt ttttagtgtc gtatcagcaa tgttagtcct gcatctgacg
     7501 ttttacctga taaggcaaat acaagactag taaaaccaaa ccagctccta gtaaggctag
     7561 aagggctagt ttttcttgga aggtaatcaa cccaacaact aattccacaa gtaaaacaaa
     7621 actggtcaat cctcgaacta cctcctgtaa gcctttttcc ttttgcccct tgtccagcgg
     7681 aaagagttgg gtcaaatact ggtagtcaaa ggcatgatag agggccagca actggaagag
     7741 caagaggtag ttaaagagaa ctaccactgc tgtcgcaatc caagcttgct cgataaaaac
     7801 ctgcgccagt acggaaagta agagaagacg aagactgaga gcaaagaggt cgccatttcg
     7861 cagataagaa cgcagataga gattttgcca aatctttcca gacaccttct gaacagcctt
     7921 taagataaag tccagatagg cacgacgttt gacactgttt gaaattccct ttacctgcgt
     7981 aaagagggca aagaaacgaa gcaagacttg cttacgcttg ctttcttggg aaatgacata
     8041 gtcccagtcc agcccagttt cagtgaaaaa tttgctggcc ttttgacgaa agtggaaata
     8101 ttttcctacc cccaataaaa gcacatagag cagaaaaact ggcaagccat aacccattgc
     8161 taaaaataaa ggcgcaaata acagcaagaa aagggtctgt acaaagagcc aaaagactag
     8221 ggaaatgcca gtttgacgct tgagatggag cttgatttcc tcttctccaa ctaagagaaa
     8281 gagcttgtct ggagcctcca tataggtggc aattcctccc caaagtaaaa gtaaaacaga
     8341 cgtaattcct acaaacaaaa ggataggcca atgattttca ggaaaatgtt gtaagagttg
     8401 actgtactgg taggctagaa agcccaacag gacaagcagg aacaagacaa agtggtcatt
     8461 gagcacatag cgcagataac caaggcactc cttacgaaag gcctgctttc tctttaaaaa
     8521 caagtctttc atagatcctc ctctttggtc agagccaagt aaatatcatt caaactagcc
     8581 tcaggcatat caaaggcttc acgtagttgc aggagattgc ctttggcacg cacctctccc
     8641 ttgtgaagaa tgacaaaggc atcacacatc ttctccgccg aatccagcac gtgggtactc
     8701 atgagaatag acttgccctt ttgcttctcc acttccaaaa gctgaatcaa atcagaaata
     8761 gccagcggat caagaccaag gaaaggctca tccacgatga aaagacttgg atccaccaca
     8821 aaagcacaga taatcatgac cttctgcttc atcccttttg aaaaatgaac agggaaccag
     8881 tctaatttct gttccaaacg gaacattttt aacaagggct ctactcgttc gaaagccact
     8941 ttttgctcaa taccgtaagc catagcaacc gtttcgatat gctctctgag ggtcaattcc
     9001 tcatacagac taggcgtctc aggaatgtag ccaatctgct tgcggtagct agtcgcatct
     9061 ccttgcagag tcaggccatt gatattgatg gagccactat aaggtgccaa cagaccgata
     9121 atctcattga tcgtcgttga tttcccagca ccattgagac caatcaaacc gaccaactgc
     9181 ccactttcaa cagtaaagga cacatctttc aaaacaggga catgaacata gccacctgtc
     9241 aggtttttaa tttctaacat attttctcca aatctggtat aatgtagcta tattatatca
     9301 aaattcagta cagtagaggt agattttatg tcagattgca ttttttgtaa aatcatcgca
     9361 ggggaaattc ctgcttcaaa agtatatgaa gatgagcagg tccttgcctt tcttgatatc
     9421 tctcaagtaa cactaggaca caccttggtc gtgccaaaag aacactatcg caatcttttg
     9481 gagatggatg ctacgagcgc cagccaactc tttgcccaag taccaaaagt agctcaaaaa
     9541 gtcatgaaag tcactaaggc tgctggtatg aatatcattt ccaactgtga agaagtcgct
     9601 ggtcaaacag tttttcatac tcacgttcac cttgtacctc gctacagtgc tgacgatgac
     9661 ctcaagattg attttatcgc ccacgaacca gactttgaca aacttgctca agtcgctgaa
     9721 accatcaaaa acgcttaagg agttgctatg aaattatcca acctactgct atttgcagga
     9781 gctgcagccg gaagttatct ggtcacaaaa aatcgccaaa ccatcacaga tgaagtcttg
     9841 aataccactg accgcgttca agctatcaag gacgatgtgg atattatcca aaacagcctg
     9901 caaatcattg accagcaaaa agaacttatc aaggaatacc aagaagactt gacttacaag
     9961 tttaaggtct tggaaaagga tatccagact agactagctg tgataaaaga aatgcaggga
    10021 actgaagata agtaaaaaga gccccccggc tcttttttaa aacgtaaaca agttatagtg
    10081 aattgaattt agaatagcac atcatagttt ctaaagcatt gttagagatt actttaaaat
    10141 cctcttatca atttgttcat attctatttc aatctactat atatatccca tcaactatgc
    10201 atcataattt aggtaactca tactcaataa aaatcaaaaa gcaaactaga aagctaggca
    10261 cagactgctc aaaacaccgt tttaaggttg tggatagaac tgacgaagtc agctcaaaac
    10321 actgttttga ggttgtggat agaactgacg aagtcagtaa ccatacccat gacaagccga
    10381 cgctgacgtg gtttgaagaa atttttgaag agtatcattc accatttcac aactaaatcg
    10441 aagactttct gccgtaatga aaacacctga aacagcttgg tttcggctgt ccggaaactt
    10501 taagacttag gttcaaagtt taggtatgga acttcgaagg aggtcgctac cgtccgtcat
    10561 tacttaggaa agtcttaaaa aatctataaa gtaaaaagag cccgacagct ctttttgttt
    10621 atactcaatg aaaatcaaaa agcaaactag gaaactagcc acgggctgct caaaacactg
    10681 ttttgaggtt gtagatacga ctgacgaagt cagtcacata tatacggcaa ggcaacgctg
    10741 acgtggtttg aagagatttt cgaagagtat tattctccat caaaggcatc tttaatatgg
    10801 tcaaagaagc cttttttctt tggatttact ttcaagtcac cagcagccgc gaattctttc
    10861 aaggctactt tttggcggtc gttcaagcct gtcggtgtta cgacattaac agtaacgtat
    10921 tggtcaccaa ctgcaccgcc acgaaggctc ggtgccccct tactacgtag gcggaacttc
    10981 ttaccagtct gagttccctc tggaataacc aattcaacat caccgtgaac agttggaata
    11041 tctactgtat caccaagagc cgcttggaca aagttgaggt tgagattgta gaagatagtc
    11101 gttccttcac gttcaaactt gtcgctagct tccacagaaa ctactacata caagtcacca
    11161 taaggtccac cgttaaagcc tgcttcacct tgaccagcga ggcgaatttg ttgacctgtt
    11221 tccacaccag cagggatttt cacatgtacg ctatgagctt gtttctcatg acctgttcca
    11281 tgacaggttg tacatggata tttgatttct tttcctcgac cgtgacagac atcacaggtt
    11341 acttggcgac gcatcatacc aagaggagtc tgcgtatcga cgttaatgac accagcgcca
    11401 tgacagcgtc cacaagtgac tggacttgtc cctggcttag caccagatcc attacatgta
    11461 cgacagccag cttcacgatg atacttaact tccttctcag ttccgaagat agcttcttca
    11521 aaggtcaaat tgacacgata ctggagatca tctccttggc gaggagcgtt tggattgcgc
    11581 gaagaaccgc ctccgccgaa gaaacttgag aaaatatcct caaaaccacc gaagccacct
    11641 gccccattga aaccgccgaa accaccagct ccaccaaaac caccattggc gcctgcagca
    11701 ccatactggt cataggcagc acgtttttgg tcgtcactca aagtctcata ggcttcttga
    11761 acttccttgt acttgtcctc agcaccaggc tccttgttga tatctgggtg atattttttg
    11821 gaaagcttac gataagcctt tttgatttcg tctgccgaag cgtttttgga tacccccaga
    11881 cgatcataaa attcagtatt gttcataatt caagatacaa agggcgtcaa acggacacag
    11941 ccatctagga gttttgacga cggacgctta cgtcctagaa aaaactatct ttttggcaca
    12001 gtccatagcc cgtgttcagt tacgaacacc cttattcctt tctattgatg ttctgaatcg
    12061 aaccaccatt taggtcgggt tcaattcctt tcttttatat ttagtaagaa attctgaaac
    12121 ccgtgttcag ttacgaacac tctttgttcc tttctattga tgagacaaaa cccaaacaaa
    12181 tgagattccg tcccttttta tcgaaaaaca gaggctgagt tgcaacctct gcaaataagt
    12241 aaattaactt tattttgatt ttaaatatcc tataagtaca gaaatattta tatatttttg
    12301 tctcttctta gtatttgcct atataattcc aattgatcat aagaaataca actactgtcc
    12361 aaatcatacc aattatgaac ggtattacaa atttatatgt ttgtatttct aatgatatca
    12421 tagctgatac catcgctgat acaaatgcag acaacaatac tgaagtaaca aaattcctta
    12481 ccgcttcatc atttttgaca caactatcat gctcagctaa tataatttct ctatatatag
    12541 tcaaacattc tactggaata ttatctataa aaccttttgc tgcttcatag ttgtcagctt
    12601 gattacaaaa atcattataa acttttcgtg tattttttag atactcttca tccaatacac
    12661 tcatcttact tttccgtaaa ctctccgtct acgacgtcat cgcctgcgtt tcctgttgct
    12721 tgtgcgcctt ctgctccttc ttgagcttgt tgcgctgctg cggcttgttc gtagagttta
    12781 acagcaagtc cttgagcttt ttcgttcaat gcttcaagtt ttgctttcat gtcgtccaag
    12841 ttgttgtctt cttgagcttt cttaaggtca tcaagggcag cttgggcagc gtcacgttct
    12901 gcgtcgaagc ctttaccttc agtttccttg attgtctttt cagtcgcaaa gattgcttgg
    12961 tctacttcat tacgaaggtc tacttcttct ttacgtttct tatcggcttc agcgtttgct
    13021 tctgcatctt tcatcatgcg gtcgatttct tcgtcagtca aacctgagtt cgattggatg
    13081 acaatagttt gttctttttg agttccaagg tctttggcct taacagacac gataccgttc
    13141 ttgtcgatgt caaatgttac ttcgatttga ggaattccac gaggtgcagc tgggatatca
    13201 gtcaattgga agcgtccaag agtcttgtta tctgctgcca ttgggcgttc accttgaaga
    13261 acgtggatat caacggctgg ttggttgtct gctgctgttg agaagacttg tgatttagat
    13321 gttgggattg tagtgttgcg atcgataagt tttgtaaata ctccacccat tgtttcgata
    13381 ccaagtgaca atggcgttac atcaagaagg acaacgtcct tgacatcacc agtaatcaca
    13441 ccaccttgga tagccgcacc catagcaact acttcatcag ggtttactga tttgtttggt
    13501 tctttaccag tttcagcttt aacagcttca acaacggcag ggatacgagt tgaaccacca
    13561 acaaggataa cttcgtcgat ttctgacaag ctcaaacctg catctgaaag ggcttgacga
    13621 actggaactt ttgtacgttc aacaaggtca cgagtcaaat cgtcaaattt cgcacgagtc
    13681 aaagtcattt ccaagtgaag aggtccagcc tcacctgcag tgataaatgg caagctgatt
    13741 tgtgttgaag ttacaccaga aaggtctttc ttcgcttttt cagccgcatc tttcaaacgt
    13801 tgcattgcca tcttgtcagt agacaagtcg ataccgtttt ctttcttgaa ttctgctacc
    13861 aagtggtcaa tgattttttg gtcaaagtcg tcaccaccaa gtttgttgtc ccctgcagtt
    13921 gacaatacgt cgaagacacc gtcacccaat tcaaggatag agacgtcgaa tgtaccacca
    13981 ccaaggtcaa ataccaagat tttttcttct ttgtcagtct tgtccaaacc ataagcaaga
    14041 gctgctgcag ttggttcgtt aacaatacgt tctacttcaa gaccagcaat tttaccagcg
    14101 tcttttgttg cttgacgttg agcgtcgttg aagtaagccg gaactgtgat aacagctttg
    14161 gttactttct caccaaggta gtcttcagcg tagcctttca agtattgaag gatcatagct
    14221 gagatttctt gtggagtgta ttcttttcca tttgcagaaa ctttttcaga agttcccatc
    14281 ttagatttga tagagataac tgtatctggg tttgtaactg cttgacgttt tgcagcatca
    14341 ccaacgatga tttctccgtt tttgaatgag actacagatg gagttgtgcg gtttccttct
    14401 gggtttgcga tgattttgct ttcagttcct tcaagaactg caactgctga gtttgttgta
    14461 cctaagtcaa taccgataat tttagacatg tgtttttctc cttgttagtt aattttctat
    14521 ttttcttttt gatactcttc ttaagtggcg acgccgtcag agcttgactt cgtcagtctc
    14581 ttttactaaa ctttgagcct aaggtctcaa aatttgcgca aatagcgcca cggcgaagag
    14641 tatcgtcttt ggttcgcttc gctcactatt acaaagccaa acatatttta tctttcttca
    14701 tagtttattg tcgtttcgga caagttttct attatgtaaa ttgcgacacg aggagtcgaa
    14761 atcgatttta tttcgacgac gagttagtaa ggaagctagg caaacgccat agcaattgcc
    14821 gttttctgac gagttgcttt agctaccgtc agaattgccg aatcgaacac gccctaagct
    14881 ctgagtaaaa aagatagatt ttcttgtgtt catcgaacac ttcgtcaatc tcctattttt
    14941 actgcgagct ttgtatctta gttatacacc actaccattg ctgggcgtag gatgcggtca
    15001 tggagtttgt agcctttttg aaagacttgg gcgatggtat ctactgggtg ttcatcgtct
    15061 gctgggagag tttggatggc catatggtag ttatggtcaa attcgccatc cgctgcgatt
    15121 tcttcaattc cttcttcttt caaagcgtga atcaagcttt cttgcaccat ccccaagccc
    15181 ttcttcacat catctgtcaa accttcaact gcaagtgcac gctcaaggtt gtcaagagat
    15241 ggtaagattg cttttgccaa gtcctggcta cgataacgtt gcaagttttg acgttcttca
    15301 ttggcacggc gttggatatt ttgcatttct gcatgagcgc gaagatattt gttttcgaac
    15361 tcatctgcac gttcatttgc caagtccaac tcagactttt caggagttgt ttcttcagct
    15421 gtttccacaa cttcctcttc ttgaacttct tctacttctt cattttttat atcttgggcc
    15481 atgttcgcct cctttaatga tttcaatctt aatgtacttc ataatgatta ctgctgaggt
    15541 agcggtaaaa atctgtcaac ttcatggtca aaacacggtt gaccacattg atttgattga
    15601 ttagctgttg gtaatccaga ttaactggac cgataatggc tagaattcca actccccgat
    15661 aaggaatgag gaacttacta ctaatcaccg ctaggtcagc taaacaggac tcttgaccgt
    15721 ctgcaacacg aacattttgc atctgatcct cacgcaaccc ctcacgaatc tccaaggcca
    15781 ccttttgcgg ttggtcaaag aactgatagg ctgctagatt ggcaaaattc aagagatgga
    15841 ccttgcccgc catcacaatg ttttcgttga acatttcctt aaagatgtgt tcaaagagat
    15901 cgatgacatt atccgttgtt gtaaagtaac gctggataat ctgcggaatc tccgtccgaa
    15961 tcttgtagtg aatatctaaa acggtgtgac cgaggaaacg ttcctgaatg atgctcttca
    16021 gtttcagcaa atcctcctgc aagaagttcc ttggaatcag aaactgacta gtaaccgttc
    16081 gcgactcgtc tagggtaaat accgccaagg ctgtatgttg ccccaaaaca acgatatcaa
    16141 aggctgtcaa ccgttgcctg ctcggctcaa catccagtgc cactaccgta cagccactca
    16201 ggtctgttag caagttagca gcctcttgca gaatatcctc caatttgaag aattcctgat
    16261 caaaggcttt gacaatctca tatacctcat tttcagccag tcggtcaaaa tccagtgagt
    16321 gtttcacata gtactgaaaa ccagcaacac ttggcatccg accgcttgaa gtatgagcct
    16381 tctcaagcaa cccttgtttt tctagttccg ccatgtcatt acgaatggtt gcactgctag
    16441 agttaataga ctcttgcaag gcttttgatc cgacaggttc gtgcgttttg gtaaagatgt
    16501 caataatcag atttaaaata tcctgctgac gctctgtaac catctcatca ctcctctctg
    16561 tctgatcaat tagcactcaa tgcatccaag tgctaactca tgattctatt atacaccctt
    16621 agaagagaat gtcaagacaa aaactcaaaa aattagcact cttttatcaa gagtgctaaa
    16681 aatcaatctg aagacctaga accttgctat tcatctactc ggtatttcct ttttagtctg
    16741 aaataaccat gaattagata agaaatcaga aaagcatata aaacaaaaat aagaaagaaa
    16801 gacatagaaa gttcctctct aaacaaactc atacaaacaa caagaccacc taagaaagta
    16861 gctgtacagg aacgaagtct agatcgcata acttcccatt tgagcccctt actcatatag
    16921 acttgatcct ctggaagtaa atcagaagac gatttacgaa gaatcgaaca agaacctgct
    16981 cctatcaatt cccaacctct atctctaaaa tcttgcagtt catgcttata ttttttaaga
    17041 aatctagaat catagatacg gtagatgaca tcgtctggtt gacattggtc aaaatagaac
    17101 aaaccaaaac gactcgttct atacctccaa cctttcaaat gcatctcatg taaatattct
    17161 tcttccttgt ccaaatcaac aatagtgaaa atccgaaatt ctactctgct attcattgtc
    17221 ttaccccaaa attagaaaac atgcctggcg ttatttatta gataattctt tccacttttg
    17281 actcaatctc caaaaaatat aagaaatctg aatcgcaaaa actatcaata aaacccaatc
    17341 tattatgaaa gtcaaaaaca cttcccaact gaaagaacta cctccagtga caaactttga
    17401 gaaaaacggt agtagagcta aaaagagaag caaaatagga agcatccgca ttgttaaaat
    17461 ccttttggca taaaaaaatc tttatttaaa ctaaaatatt atggcaaaat ttacgccagt
    17521 ttttgaacgg ctgatgtaga tattttatac tttcaaaatg tttaaatgtg attatttatt
    17581 tttgaaaaat agctcaccag cccgactgaa agtgcttata gaatgataat aagtcgcctg
    17641 ccgaaaacag cggaaaatag cggtgttatg cggagataat ctgacgcgat gcgaaagtat
    17701 attgcatact tattttcaac aatttagcag agtattttta taagtgtgat ataatagaag
    17761 tataatttgt tctgatagtt tattttatgg agaagtagat ttttagaatg cggaggattc
    17821 aatatggttg agtttataaa gtctaagaaa gaaatgagtg aggaggatat taaagcaaat
    17881 ttcatcactc ctgctattgt atccaaagga tggaaaaatg gtgagcatat cgcttacgaa
    17941 gaatacttca ctgatggtcg aattgaggtt agaggagata aggctcgtcg taaagaagga
    18001 aaaaaatcag actattcact gtattaccaa tttggaactc gaattgcaat tgttgaggca
    18061 aaggataata aacacagcgt tcgagcagga ttacaacaag ctattgaata tggagagatt
    18121 ttagatgttc catttgttta ttcttcgaat ggtgatggct ttattgaaca cgaccgtatc
    18181 acgagagaag aacgtgagct ggagttagac gaattcccta ctcgtgaaga attattttct
    18241 cgtatgacga aggaaaaagg attgacgtac gaaattacag aagctatctc aactccatac
    18301 tatacagacg ccttctcaat gaaaacgcca cgctattatc agcaaatagc tatcaaccgt
    18361 actattgaaa cagttgccag aggacaaaaa cgagtaatgt ttgtgatggc aacaggaacg
    18421 gggaaaacgt tcatggcttt tcaaattatt catcgccttc gaaaagctgg tttggctaaa
    18481 cgagttttat tcttagcgga tagaaacatc ttagtagacc aaacgatggc tgaagacttt
    18541 aagccattcg aaaaggtaat gacgaaaatt acaccaaaac ttttgactgc tcctgaaaaa
    18601 ttaaattctt ttgaaattta tctagggctt tatcagcaac taactggtga agatggaact
    18661 gaaacacatt atcaaaaatt tgacaaagac ttctttgatt taatcgtaat tgatgaagcg
    18721 caccgtggtt cagctaagga aaacagtaac tggcgtaaga taattgatta tttcagttct
    18781 gcgacacaga ttgggatgac cgctactcct aaagaaacca agaatgcttc caatacggaa
    18841 tactttggtg agccaatcta tacttatagt ttaaaacagg gaatcgagga tggttttttg
    18901 gctccatatc gtgttatgag ggttaattta gatgtggatg tggatggtta tcgtccagaa
    18961 actggaaaag ttgatgctaa cggacaatta atagaagata ggtactacgg caggaaagat
    19021 tttgataaaa ccattgtcat tgatgataga acgcaaagag ttgccaagtt tgtttctgat
    19081 tatatgaagc aaaacaatgc acgatttgat aaaacaattg ttttttgtgt tgatattgac
    19141 catgccgagc gaatgcgtgc tgcacttgta aaagagaatc tagacttagt ccaagaagac
    19201 tatcgttatg tcatgcaagt aactggtgac aacgctgaag gaaaagctca actggataac
    19261 tttatggatg tcaattctaa ttttcccgct attgtaacaa cgtctaaatt attaacgaca
    19321 ggagttaatg ctaaaacatg tcgtttgatt gttttagact ctaatatcca atccatgact
    19381 gaatttaaac aaattattgg tcgtggcaca cgtctttatc ctcaaaaggg gaaagaattt
    19441 tttacgatta ttgattttcg aaatgttacc aatttgtttg ctgaccctga ttttgatggt
    19501 gatccagtga aggtgctgga aacaggtgcg aaaacagtca gtggttctac gcccggtttc
    19561 gtagatgagg aaggtgaccc agtagaaaaa tatatcgtta cagacaagca ggttaccatt
    19621 cttaattcta ctgttcaagt attggatgaa aacgggaaac tgattaccga aagcctgacc
    19681 gactacactc ggaagaatat cttaggtagc tacgccactt tgaacgattt tatcacagtt
    19741 tggcatacgg cggataaaaa gaagcttatc ttagacgaac tttataaaaa aggagtttat
    19801 ctagatgcta ttcgagagtc ggagggaata tcagaacaag aaatcgatga ttttgattta
    19861 ctcctaaaac ttgcctatgg tcaaaaagaa ttaaccaaaa cggaacgtat caataaactc
    19921 aaacaaagcg gatatttata taaatatagt gaggaagcgc gtgctgtttt ggaaatttta
    19981 ctgaacaaat acatggataa aggtattgga gaactcgaaa gcattgaaac attaaaactt
    20041 ccagaatttc agatatatgg tggaaccttc aaaatcatca atacttattt tggagataaa
    20101 aaacgatatt tacaagcaat taaagaattg gagcaagagc tatttacagt agcttaatga
    20161 aaggaaagta tgtcaattac atcatttgta aaaagaattc aagatatcac tcgaaacgat
    20221 gctggtgtta atggtgatgc tcaacgtatt gagcaaatgt cttggttatt attcttaaaa
    20281 atttatgata gccgtgaaat ggtttgggaa ttagaagaag acgagtatga gtcaattatc
    20341 ccagaggaat taaaatggcg aaattgggct catgctcaaa atggggaacg ggtattgaca
    20401 ggcgatgaat tacttgattt tgtcaataac aagttattca aagagttgaa agagcttgaa
    20461 ataacttcaa atatgcctat tcgaaaaacg attgttaaat cagcttttga agatgcgaac
    20521 aactatatga aaaatggcgt cttgttacgc caagtcatca atgttattga tgaagttgat
    20581 ttcaatagcc ctgaagatcg tcattcgttt aatgatattt acgaaaaaat tcttaaagat
    20641 attcaaaatg ctgggaactc aggagaattt tatacgccac gtgcagcgac tgattttatt
    20701 gccgaagttc ttgacccaaa acttggagaa tcaatggcag accttgcttg cggaacagga
    20761 ggcttcttga cttcgactct gaaccgttta agtagtcaac gtaaaactag tgaagatacc
    20821 aaaaaatata atacagctgt ttttggtatt gaaaagaaag catttcctca tcttttagca
    20881 gttacaaatc tgtttcttca cgaaattgat gaccctaaaa ttgttcatgg aaatactttg
    20941 gagaaaaatg ttcgtgaata tacggatgat gaaaaatttg acattattat gatgaatcca
    21001 ccttttggag ggtcagaatt agaaacaata aaaaataact ttccagcaga attacggagt
    21061 tctgaaacag ctgatttatt tatggctgtc attatgtatc gtttgaaaga aaatggtcgt
    21121 gttggagtta ttttacctga tggttttcta tttggtgaag gtgtaaaaac tcgcttgaaa
    21181 caaaaactgg tagatgagtt caacttacat acgattatta ggttgcctca tagtgtcttt
    21241 gcaccgtata caggaatcca tacgaacatt cttttctttg ataaaacaaa gaaaacagaa
    21301 gaaacttggt tttatcgttt agatatgcca gatggttata aaaatttctc gaaaactaag
    21361 ccgatgaagt cagaacactt caatcctgtt tgtgactggt gggaaaatcg tgaagagatt
    21421 ctggaaggta agttctacaa atctaaatca tttacaccta gtgaattggc tgagttgaat
    21481 tataatttag accagtgtga ctttccaaaa gaggaagagg aaatcttaaa tccctttgag
    21541 ttgattcaga attatcaagc ggaaagagca actttaaatc ataagattga taatgtatta
    21601 gctgatattt tgcagttgtt ggaggacaaa taatgacacc agaacaactt aaagcaagta
    21661 ttctccaaag agcgatggaa gggaaattag tgccgcaaaa tcccaatgac gaacctgcaa
    21721 gtgaattatt aaagagaatt aaagctgaaa aagaaaaact tatcagtgaa ggaaaaatca
    21781 aacgagataa aaaggaaact gagatatttc gtggtgatga tgggaaacat tatgggaagt
    21841 ttgctgatgg aagtactcaa gaaattgatg ttccttatga tattcctgat acttgggagt
    21901 gggtgaggtt ttctacattg gttgaaattg tcagaggtgg ctctccacga ccaatcaaag
    21961 attatcttac ttctgaagta gatggaataa attggataaa aataggtgat actgaaaagg
    22021 gtgaaaagta tataaataat gttaaagaaa aaatcaaaaa atcagggctt aacaaaacta
    22081 gatttgtaaa aaaaggtaca tttttgttaa ctaattctat gagttttggt agaccttata
    22141 ttttgaatgt tgatggtgca atacacgatg gatggttggc tatttcgaac tatgaaaact
    22201 cattaaataa agattaccta ttctatattc tttcatcaaa tgtagtttat tctcaatttc
    22261 tatctctaat tagtggagct gttgtgaaaa acttgaatag tgataaagtt gcttctattc
    22321 ttatccctct ccctccgcta gctgaacaac aacgcataat agaagcaatc gaatcagctt
    22381 tagaaaaagt agatgaatat gctgaaagtt ataatagact agaacagcta gataaa
//
LOCUS       DAVLZS010000032        22218 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLZS010000032 DAVLZS010000000
VERSION     DAVLZS010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22218
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.032"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            108..977
                     /gene="rfbA"
                     /locus_tag="VYO88_001348"
     CDS             108..977
                     /gene="rfbA"
                     /locus_tag="VYO88_001348"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV1719437.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSKMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PEHPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLGRGDLSVEVMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEISYRMGYISREDALALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            978..1571
                     /locus_tag="VYO88_001349"
     CDS             978..1571
                     /locus_tag="VYO88_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV1719438.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            1584..2633
                     /gene="rfbB"
                     /locus_tag="VYO88_001350"
     CDS             1584..2633
                     /gene="rfbB"
                     /locus_tag="VYO88_001350"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV1719439.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLREELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            2699..3550
                     /gene="rfbD"
                     /locus_tag="VYO88_001351"
     CDS             2699..3550
                     /gene="rfbD"
                     /locus_tag="VYO88_001351"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV1719440.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            3626..4060
                     /locus_tag="VYO88_001352"
     CDS             3626..4060
                     /locus_tag="VYO88_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1719441.1"
                     /translation="MLLVLVSLAHSFGSVSIIAHIIHQKINLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            4136..4582
                     /locus_tag="VYO88_001353"
                     /pseudo
     CDS             4136..4582
                     /locus_tag="VYO88_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4653..4811
                     /locus_tag="VYO88_001354"
     CDS             4653..4811
                     /locus_tag="VYO88_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV1719442.1"
                     /translation="MSLLETAKRHQLNSEKYLFYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            5013..6995
                     /locus_tag="VYO88_001355"
     CDS             5013..6995
                     /locus_tag="VYO88_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1719443.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYIIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKVLDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            7296..12599
                     /locus_tag="VYO88_001356"
     CDS             7296..12599
                     /locus_tag="VYO88_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEV1719444.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPANLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGADVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFFVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTSLFLASVSLALSALFVVKTKKD"
     gene            complement(12766..14925)
                     /locus_tag="VYO88_001357"
     CDS             complement(12766..14925)
                     /locus_tag="VYO88_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV1719445.1"
                     /translation="MNKPTILRLIKYLNISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(14922..15518)
                     /gene="recU"
                     /locus_tag="VYO88_001358"
     CDS             complement(14922..15518)
                     /gene="recU"
                     /locus_tag="VYO88_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1719446.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            15584..16111
                     /locus_tag="VYO88_001359"
     CDS             15584..16111
                     /locus_tag="VYO88_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1719447.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            16181..16510
                     /gene="gpsB"
                     /locus_tag="VYO88_001360"
     CDS             16181..16510
                     /gene="gpsB"
                     /locus_tag="VYO88_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1719448.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            16531..16911
                     /gene="rnpB"
                     /locus_tag="VYO88_001361"
     ncRNA           16531..16911
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYO88_001361"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            16996..18153
                     /locus_tag="VYO88_001362"
     CDS             16996..18153
                     /locus_tag="VYO88_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1719449.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KAWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            18166..19560
                     /gene="mapZ"
                     /locus_tag="VYO88_001363"
     CDS             18166..19560
                     /gene="mapZ"
                     /locus_tag="VYO88_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1719450.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     PASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            19636..21060
                     /gene="gndA"
                     /locus_tag="VYO88_001364"
     CDS             19636..21060
                     /gene="gndA"
                     /locus_tag="VYO88_001364"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1719451.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARFISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            21072..21761
                     /locus_tag="VYO88_001365"
     CDS             21072..21761
                     /locus_tag="VYO88_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719452.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(21797..>22218)
                     /locus_tag="VYO88_001366"
     CDS             complement(21797..>22218)
                     /locus_tag="VYO88_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1719453.1"
                     /translation="SDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHF
                     QNKDPEKFFGLIEDNLKQIHPIFQTVFKTFLKNKEKIVNALQLPYSNAKLEATNNLIK
                     LIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
BASE COUNT         6843 a         4040 c         5066 g         6269 t
ORIGIN      
        1 actttgatta attaaaaatt agcaaaattt attgacattt tgtttttata aattgcaata
       61 aaggtctaat tctgaatttc agtgaatata agaaagggat cctactaatg aaaggtatta
      121 ttcttgcagg tggttcgggg acacgattat atcctttgac tcgggctgca tcaaaacaac
      181 ttatgccggt ttatgataaa cccatgattt actatccact ttcaacattg atgttggctg
      241 ggattaggga tattttgata atctcaactc ctcaagattt gcctcgtttt aaagagcttc
      301 ttcaagacgg atctgagttt gggattaaac tttcttatgc agagcaacca agtccagatg
      361 gtttggcaca agcctttatc attggggaag agtttattgg tgatgatagt gttgctttga
      421 tcttggggga caatatctat cacggccctg gtttgagcaa aatgcttcaa aaagcagcca
      481 agaaagagaa aggtgcgact gtctttggct atcaagtgaa ggatccagag cgttttggtg
      541 tggttgagtt tgatacagac atgaatgcta tttctatcga agaaaagcca gagcaccctc
      601 gttcaaacta tgcagttaca ggactctatt tctatgataa tgatgtagta gagattgcca
      661 aaagtataaa accaagccct cgtggtgaac tggaaattac agatgtaaac aaggcttacc
      721 taggtcgtgg agatttatcc gttgaggtta tgggacgagg ctttgcttgg ctggatactg
      781 gcactcatga aagtttatta gaggcttcgc agtacatcga aacagtccaa cggatgcaaa
      841 atgttcaggt ggcaaacttg gaagaaattt cttaccgtat gggctatatc agtcgagaag
      901 atgcattggc cttagcccaa ccacttaaga aaaatgaata cggacagtat ctgctccgtt
      961 tgattggaga agcatagatg acagataatt ttttcggtaa gacgcttgcg gcacgcaagg
     1021 ttgaagctat tccaggcatg ttggagtttg atatccccgt tcatggagat aatcgtggct
     1081 ggtttaaaga aaatttccaa aaggaaaaaa tgcttccact tggatttcca gagtctttct
     1141 ttgcagaagg aaaattgcaa aacaatgtat ccttctcacg taaaaatgtc cttcgaggcc
     1201 tccacgcaga gccttgggat aagtacatct ctgtagcaga tggagggaaa gttctgggtt
     1261 cttgggttga tctacgcgag ggtgaaacct ttgggaatac ctatcagaca gtgattgatg
     1321 cgagtaaggg aatctttgtt cctcgaggcg tagctaatgg cttccaagtt ttatcagata
     1381 cagtgtcata tagctatctg gtcaatgatt actgggctct tgaactcaaa cccaagtatg
     1441 cctttgtgaa ctacgctgat ccaagccttg gtattgaatg ggaaaatatt gcagaagcag
     1501 aggtttcaga agcagataaa catcatcccc tacttaagga tgtaaaacct ttgaaaaaag
     1561 aagatttgta aaaaggaaag aatatgactg aatacaaaaa tattatcgtg acaggtggag
     1621 ctggctttat cggttctaac tttgtccatt atgtttacga gaactttcca gatgttcatg
     1681 tgacagtcct agataagttg acttatgctg gaaaccgcgc gaatattgag gaaattttag
     1741 gtaatcgtgt tgagttagtt gttggtgaca ttgctgatgc ggagttggta gacaagttgg
     1801 ctgctcaagc agatgctatc gttcattatg cagcggaaag ccacaatgat aattcgctca
     1861 atgatccatc gccatttatt catactaact tcatcggaac ctatactctt ttagaagctg
     1921 ctcgtaagta tgatattcgc ttccaccatg tatcgacaga tgaagtttat ggggatctcc
     1981 ctttacgcga agatttgcca ggtcatggtg aaggaccagg tgagaaattt actgctgaaa
     2041 caaaatacaa cccaagctct ccgtactcat caaccaaggc agcctcagat ttgattgtca
     2101 aagcctgggt gcgttctttt ggagtcaagg caacgatttc caactgttca aataactacg
     2161 gtccttatca acatatcgaa aaattcatcc cacgtcagat tactaacatc ctaagtggta
     2221 tcaagccaaa actttacggt gaaggtaaga acgttcgtga ttggattcat accaatgacc
     2281 attcttcagg agtttggaca atcttgacaa aagggcaaat cggtgaaacc tacttgattg
     2341 gggctgatgg tgagaagaac aataaggaag ttttggaact tatccttaag gaaatgggac
     2401 aagctgcgga tgcctatgat catgtgactg accgtgcagg acatgacctt cgctatgcga
     2461 ttgatgctag caagctccgt gaggagttgg ggtggaaacc tgaatttacc aactttgaag
     2521 ctgggctcaa ggcaacaatc aagtggtata cagataacca agaatggtgg aaagcagaaa
     2581 aagaagctgt tgaagccaat tatgctaaaa ctcaggagat tattacagta taaaaagcag
     2641 gaaatagctg ctttttattg ctatattggg aagagttaca tattagaaag gtctagagat
     2701 gattttaatt acaggggcaa atggccaatt aggaacggaa cttcgctatt tattggatga
     2761 acgtaatgaa gaatacgtgg cagtagatgt ggctgagatg gacattacca atgaagaaat
     2821 ggttgaaaaa gtttttgaag aggtgaaacc gactttagtc taccactgtg cagcctacac
     2881 cgctgttgat gcagcagagg atgaaggaaa agagttggac ttcgccatca atgtgacggg
     2941 gacaaaaaat gtcgcaagag catctgaaaa gcatggtgca actctagttt atatttctac
     3001 ggactatgtc tttgacggta agaaaccagt tggacaagag tgggaagttg atgaccgacc
     3061 agatccacag acagaatatg gacgcactaa gcgtatgggg gaagagttag ttgagaagca
     3121 tgtgtctaat ttctatatta tccgtactgc ctgggtattt ggaaattatg gcaaaaactt
     3181 cgtttttacc atgcaaaatc ttgcgaaaac tcataagact ttaacagttg taaatgacca
     3241 gtacggtcgt ccgacttgga ctcgtacctt ggctgagttc atgacctacc tagctgaaaa
     3301 tcgtaaggaa tttggttatt atcatttgtc aaatgatgcg acagaagaca caacatggta
     3361 tgattttgca gttgaaattt tgaaagatac agatgtcgaa gtcaagccag tagattccag
     3421 tcaatttcca gccaaagcta aacgtccgct aaactcaacg atgagcctgg ccaaagccaa
     3481 agctactgga tttgttattc caacttggca agatgcattg caagaatttt acaaacaaga
     3541 agtgagataa gtagtagaat gattttctag tctaataaaa gaggcagata atgaactcca
     3601 aaggagctta agatgtacga ttatcttgtt gttggtgctg gtctctttgg cgcatagctt
     3661 tggctcagtt tctattatcg ctcacatcat ccatcagaag attaatctga aggtacccaa
     3721 ttatcgccaa gaagaagatt gggctaggat gggtttacca atcacacgta aggaaatctc
     3781 taattggcat atcaaggcaa gtcaatacta tttagagtcc ctttataacc ttttacgaga
     3841 aaagttgtta gaacaacctc ttcttcatgc ggatgaaacc tcttatcggg ttctagagag
     3901 tgatagccat ctgacctact attggacctt tttgtctggg aaagctgaga atcaagcaat
     3961 cacgctgtac catcatgatc agcgtcggag tggtttagta gtacaagaat tcctaggaga
     4021 ttattctggc tatgtgcatt gtgatatgtt gcggcagtaa cttaggactt tagtcctcta
     4081 gttctgccta tgcgatagca gtccaaggtt taggagcaag gcgacgctaa gcttggtaaa
     4141 ctgcgaaccg ctagaagctt atcgtcaact ggaagaagct gaacttgttg gatgttgggc
     4201 acatgtgaga aggaagtttt ttgaagcgac ccccaagcaa gcagataaat catccttaga
     4261 agctaaaggt ttagcttatt gtgatcagtt attttccctg gaaagagact gggaggcttt
     4321 gccagctgat gaacgactac agaaacgtca agaagagctc caacccctaa tggaagactt
     4381 ctttgcttag tgccggcgtc agtcagtttt agcaggttca aaactaggaa gggcaattga
     4441 atacagcctc aagtatgaag aaacctttaa gactattttg aaagacggac atctggtcct
     4501 ttccaataat ctagctgaac gcgccattaa atcattggtt atgggacgga gtaaaagagt
     4561 tcagtggact cttttagcct aagctaaatt ttaaaaagcg agggtggtta ttttctcaaa
     4621 gttttgaagg agctaaagca acagctatta ttatgagttt gttggaaaca gctaaacgtc
     4681 atcaattaaa tagcgagaaa tatctattct atcttctaga atgtcttcca aacgaggaaa
     4741 ctctcgtaaa caaagaggtt ttagaggctt atttaccatg gactaaagtt gtacaagaaa
     4801 agtgcaaata agaaatctcc agattaggaa ctatccgtga gttctctagt ctggagattt
     4861 ttcaatatac ttcgttattg ggcgcttaca atgatattca tattttttgc aaagatgttg
     4921 tttgaaaaat aattttcaaa aattctgaaa attctgttga caactttctg aaaagagtct
     4981 ataatggaga gaaagtttta aaggagaaaa tgatgaaaag ttcaaaacta tttgcccttg
     5041 cgggcgtgac attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagcg
     5101 ctaaaggtga gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt
     5161 tgacaactgc taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag
     5221 aaaatgatcg ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg
     5281 atggattgac ttacacttat attatccgta aggatgcaaa atggtatact tctgaagggg
     5341 aagaatacgc ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata
     5401 aaaaatcaga tgctctttac cttgttcaag aatcaatcaa agggttggat gcctatgtaa
     5461 aaggggaaat caaagatttc tcacaagtag gaattaaggt tctggatgaa cagacagttc
     5521 agtacacttt gaacaaacca gaaagcttct ggaattctaa gacaaccatg ggtgtgcttg
     5581 cgccagttaa tgaagagttt ttgaattcaa aaggagatga ttttgccaaa gctacggatc
     5641 caagtagtct cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcctctg
     5701 ttgaatttgc gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta
     5761 aattgtcatt ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta
     5821 gccttacagc agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta
     5881 tgaaggacaa tattgtctat actcaacaag actctattac gtatctagtc ggtacaaata
     5941 ttgaccgtca gtcctataaa tacacatcta agaccagcga tgaacaaaag gcatcgacta
     6001 aaaaggctct cttaaacaag gattttcgtc aggctattgc ctttggtttt gatcgtacag
     6061 cctatgcctc tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg
     6121 ttccaccaac atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat
     6181 tggttactta tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt
     6241 acaatccaga aaaagccaag gctgaatttg ctaaagctaa atcagcctta caagcagaag
     6301 gtgtgacttt cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc
     6361 agcgcgtcca atctatgaaa caatccttgg aagcaacttt aggagctgat aatgtcatta
     6421 ttgatatcca acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg
     6481 ctgctggcga agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc
     6541 catcaaccta ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag
     6601 ggtttgactc aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa
     6661 aattggttac tgaggctggt gatgaggcta cagatgttgc taaacgctat gataaatacg
     6721 ctgcagccca agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag
     6781 ggcgtccaat cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata
     6841 aaggtacaag tgaaccaatc ttatataaat acttggaact tcaagacaag gcagtcactg
     6901 tagatgaata ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa
     6961 aggctcaaga agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt
     7021 tagtatttct cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta
     7081 ctgaccccca aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta
     7141 cttgtttcct attgctttct cagctattat ttgttatatt aaaagtataa ttatttttta
     7201 tttatcaggg ttaagcattg cactttcaga ggaaggagta ttttttaaaa agaaaatgta
     7261 aacgcttgct aaaaaatgaa aggatttaga agtttatgaa taaaggatta tttgaaaaac
     7321 gttgtaaata tagtattcgg aaattttcat taggtgttgc ttctgttatg attggagctg
     7381 cattctttgg gacaagtccg gttcttgcag atagcgtgca gtctggttcc acggcgaact
     7441 taccagctaa tttagctact gctcttgcaa cagcaaaaga gaatgatgga cgtgattttg
     7501 aagcgcctaa ggtgggagaa gaccaaggtt ctccagaagt tacagatgga cctaagacag
     7561 aagaagaact attagcactt gaaaaagaaa aaccagctga agaaaaacca aaagaggata
     7621 aacctgcagc tgctaaacct gaaacaccta agacggtaac ccctgaatgg caaacggtag
     7681 agaaaaaaga acaaaaggga acagtcacta tccgagaaga aaaaggtgtc cgctacaacc
     7741 aactatcctc aactgctcaa aatgataacg caggtaaacc agccctgttt gaaaagaagg
     7801 gcttgaccgt tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa gaagattctg
     7861 aaaagggcaa atcacgcttt ggtgtcttct tgaaatttaa agataccaat aataatgttt
     7921 ttgtcggtta tgacaaggat ggctggttct gggagtataa atctccaaca actagcactt
     7981 ggtatagagg tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt ctctctatca
     8041 ctctcaagtc agacggtcag ctaaatgcca gcaataacga tgtcaatctc tttgacacag
     8101 tgactctacc agctgcggtc aatgaccatc ttaaaaatga gaagaagatc cttctcaagg
     8161 cgggctctta tggcaatgac cgtacggttg tcagcgttaa aacagacaat caagaaggcg
     8221 taaaagcgga tgatactcct gcccagaaag aaacaggtcc ggttgttgac gatagcaagg
     8281 tgacttatga tacgatccag tctaaggtac ttaaggcagt aattgaccaa gccttccctc
     8341 gtgtcaagga atacagcttg aatggacata ctttgccagg acaggtgcaa cagttcaacc
     8401 aagtctttat caataaccac cgaatcaccc ctgaagtcac ttataagaaa atcaatgaga
     8461 caacagcaga gtacttgatg aagattcgcg atgatgctca cttaatcaat gcggaaatga
     8521 cagtacgctt gcaagttgtg gacaatcaat tgcactttga tgtgaccaag attgtcaacc
     8581 acaatcaagt cactccaggt caaaagattg atgacgaaag aaaactactt tcttctatta
     8641 gtttcctcgg caatgcttta gtctctgttt ctagtgatca aactggtgct aagtttgatg
     8701 gggcaaccat gtcaaacaat acgcatgtca gcggagatga tcatatcgat gtaaccaatc
     8761 caatgaagga tttggctaag ggttacatgt atggatttgt ttctacagat aagcttgctg
     8821 ctggtgtttg gagtaactct caaaacagct atggtggtgg ttcgaatgac tggactcgtt
     8881 tgacagctta taaagaaaca gtcggaaatg ccaactatgt aggaatccac agctctgaat
     8941 ggcaatggga aaaagcttat aagggcattg ttttcccaga atacacgaag gaacttccaa
     9001 gtgctaaggt tgttatcact gaagatgcca atgcagacaa gaaagttgat tggcaagatg
     9061 gtgccattgc ttatcgtagc attatgaaca accctcaagg ttgggaaaaa gttaaggata
     9121 tcacagctta ccgtatcgcg atgaactttg gttctcaagc acaaaaccca ttccttatga
     9181 ccttggatgg tatcaagaaa atcaatctcc acacagatgg tcttgggcaa ggtgttctcc
     9241 ttaaaggata tggtagcgaa ggccatgact ctggtcactt gaactatgct gatattggta
     9301 agcgtatcgg tggtgtcgaa gacttcaaga ccctaattga gaaggctaag aaatatggag
     9361 ctcatctagg tatccacgtt aacgcttcag aaacttatcc tgagtctaaa tacttcaatg
     9421 aaaaaattct ccgtaagaat ccagatggaa gctatagcta tggttggaac tggctagatc
     9481 aaggtatcaa cattgatgct gcctatgacc tagctcatgg tcgtttggca cgttgggaag
     9541 atttgaagaa aaaacttggt gacggtctcg actttatcta tgtggacgtt tggggtaatg
     9601 gtcaatcagg tgataacggt gcctgggcta cccacgttct tgctaaagaa attaacaaac
     9661 aaggctggcg ctttgcgatc gagtggggcc atggtggtga gtacgactct accttccatc
     9721 actgggcagc tgacttgacc tacggtggct acaccaataa aggtatcaac agtgccatca
     9781 cccgctttat ccgtaaccac caaaaagatg cttgggttgg ggactacaga agttatggtg
     9841 gtgcagccaa ctatccactg ctaggtggct acagcatgaa agactttgaa ggctggcaag
     9901 gaagaagtga ctacaatggc tatgtgacta acctctttgc tcatgacgtc atgactaagt
     9961 acttccaaca cttcactgta agtaaatggg aaaatggtac accggtgact atgaccgata
    10021 acggtagcac ctataaatgg actccagaaa tgcgagtgga gttggtagat gctgacaata
    10081 ataaagtagt tgtaactcgt aagtcaaatg atgtcaatag cccacaatat cgcgaacgta
    10141 cagtaacgct caacggacgt gtcatccaag atggttcagc ttacttgact ccttggaact
    10201 gggatgcaaa tggtaagaaa ctttctactg ataaggaaaa gatgtactac ttcaatacgc
    10261 aggccggtgc aacaacttgg acccttccaa gcgattgggc aaagagcaag gtttaccttt
    10321 acaagctaac tgaccaaggt aagacagaag agcaagaact aactgtaaaa gatggtaaaa
    10381 ttaccctaga tcttctagca aatcaaccat acgttctcta tcgttcgaaa caaactaatc
    10441 ctgaaatgtc atggagtgaa ggcatgcaca tctatgacca aggatttaat agcggtacct
    10501 tgaaacattg gaccatttca ggcgatgctt ctaaggcaga aattgtcaag tctcaagggg
    10561 caaacgatat gcttcgtatt caaggaaaca aagaaaaagt tagtctcact cagaaattaa
    10621 ctggtttgaa accaaatacc aagtatgccg tttatgttgg tgtagataac cgtagtaatg
    10681 ccaaggcaag tatcactgtg aatactggtg aaaaagaagt gactacttat accaataagt
    10741 ctctcgcgct caactatgtt aaggcctacg cccacaatac acgtcgtgac aatgctacag
    10801 ttgacgatac aagttacttc caaaacatgt acgccttctt tacaactgga gcggacgtct
    10861 caaatgttac tctgacattg agtcgtgaag ctggtgatca agcaacttac tttgatgaaa
    10921 ttcgtacctt tgaaaacaat tcaagcatgt acggagacaa gcatgataca ggtaaaggca
    10981 ccttcaagca agactttgaa aatgttgctc agggtatctt cccatttgta gtgggtggtg
    11041 tcgaaggtgt tgaagataac cgcactcact tgtctgaaaa acacaatcca tatacacaac
    11101 gtggttggaa tggtaagaaa gtcgatgatg ttatcgaagg aaattggtca ctcaagacaa
    11161 atggactagt gagccgtcgt aacttggttt accaaaccat cccacaaaac ttccgttttg
    11221 aagcaggtaa gacctaccgt gtaacctttg aatacgaagc aggatcagac aatacctatg
    11281 cttttgtagt cggtaaggga gaattccagt caggtcgtcg tggtactcaa gcaagcaact
    11341 tggaaatgca tgaattgcca aatacttgga cagattctaa gaaagccaag aaggcaacct
    11401 tctttgtgac aggtgcagaa acaggcgata cttgggtagg tatctactca actggaaatg
    11461 caagtaatac tcgtggtgat tctggtggaa atgccaactt ccgtggttat aacgacttca
    11521 tgatggataa tcttcaaatc gaagaaatta ccctaacagg taagatgttg acagaaaatg
    11581 ctctgaagaa ctacttgcca acggttgcca tgactaacta caccaaagag tctatggatg
    11641 ctttgaaaga ggcggtcttt aacctcagtc aggccgatga tgatatcagt gtggaagaag
    11701 cgcgtgcaga gattgccaag attgaagctt tgaagaatgc tttggttcag aagaaaacgg
    11761 ctttggtagc agatgacttt gcaagtctta cagctcctgc tcaggctcaa gaaggtcttg
    11821 caaatgcctt tgatggcaat gtgtctagtc tatggcatac atcttggaat ggtggagatg
    11881 taggcaagcc tgcaaccatg gtcttgaaag aaccaactga aatcactgga cttcgttatg
    11941 ttccacgtgg atcaggttca aatggtaact tgcgtgatgt gaaacttgtt gtgacagatg
    12001 agtctggcaa ggagcatacc tttactgcaa ctgattggcc agataacaat aagccaaaag
    12061 acattgattt tggtaagaca attaaggcta agaaaattgt ccttacaggt actaagactt
    12121 acggagatgg tggcgataaa taccaatctg cagcggaact catctttact cgtccacagg
    12181 tagcagaaac acctcttgac ttgtcaggct atgaagcagc tttggctaaa gctcagaaat
    12241 taacagacaa agacaatcaa gaggaagtag ctagtgttca ggcaagcatg aaatatgcga
    12301 cggataacca tctcttgacg gaaagaatgg tggaatactt tgcagattat ctcaaccaat
    12361 taaaagattc tgctacgaaa ccagatgctc caactgtaga gaaacctgag tttaaactta
    12421 gctctttagt ttccgagcaa ggtaagacgc cagattataa gcaagaaata gctagaccag
    12481 aaacacctga acaaatcttg ccagcaacag gtgagagtca atctgacaca tccctcttcc
    12541 tagcaagtgt tagtctagcc ctatctgctc tctttgtagt aaaaacgaag aaagactagt
    12601 atttagtaaa acctcttaac aagattacgg aagcagtctc tatcttttcc aatgaggttt
    12661 atagtacaga aaaagcctga gaagatgtct tctcaggctt ttgttaagca cataaataca
    12721 atagtgctat gacaaaatca cccagaaaaa tctgggtgat aaatgttatg gttgtgctgg
    12781 ttgaggattc tgattttgtt gatcaggggt tgtatttgat tgttgcgtat tattgttagg
    12841 attggtagtc gtactattat ttgtgcttgg agtggttgag ctagactgtg aagttgaact
    12901 atctgatgat gagcttgaac tttcagttga tgggggttgt tgtggagcag gtgagttcca
    12961 cgtagaacga gcaccatttt taaatacgaa ttctccattt ctgtagagcc cctctggtat
    13021 attccaatct tctggattgc ttccttcaga caggtaggtc atcatagagc ggtaaacttt
    13081 ggcagcgact gtaaggccat tgcctacaag tggtgtcaga cggttagaat agcctgtcca
    13141 tacagccatt gaatatttac gcgtatagcc agcaaatagt tcgtcaggtg ctacaaattg
    13201 agaggtcttg atgtggtttt caatttcctc gtctgtatag ttagaggttc ctgttttacc
    13261 agcctgaggg agccaagcaa gataggcatt tcgtccagtt ccataactca agactgtttt
    13321 catcatgtcg gtcatcatat aggctgtcgt ttccttcatg gcacgagttc cgacattaga
    13381 gaactctttt tcactcccat cactaaagac gactttatgg atatacattg gtttatagta
    13441 agttccacca tttgcaaagg cagcgtaagc agcagccatc ttttcactac ttgctccata
    13501 ttttttgtct gattcggttg tgttacttga aatggcattt gagtagtgaa tacttgggta
    13561 gtcgattccg agaccattta ggaaagtctt ggcgcggttg agtccgacct tgtttagagt
    13621 ttccacggct gggacgtttc gcgattgttg cagggcgtat tgcaaggtga tgttgccaaa
    13681 gtagccccta tcccagttat aaacaggggt atttgtccca gggtagttat agggttcatc
    13741 gtgaacgata gtagcagttg aatcgtagac accgtactcc aaggcaggag catagtctgt
    13801 gatcggtttc atagttgatc cccagtcgcg gtttgtttct actgcttggt taattccgaa
    13861 ggaaacatta cttgactgat ggcgtgctcc tagctgggca atgactttac cgttagaaac
    13921 atcaacaatg gtagaagcga cttgcaattc atcgtctgga taggcaacgt attcgtctgt
    13981 attgtaaata tcccacagat gtttttgagc ttcttggtct acatttgtgt agacatccat
    14041 cccagttgtg agcaggttat agcctgtttc ttcttcaact tgattgatga cttccttgag
    14101 gtaattatcc atgtaagcag ggtaattact tgctgatttg agactttgta gtccatcagt
    14161 aattggtgta ttgactgctt tctcatactg ttcagcagag atgtagcctt gatttttcat
    14221 ttcagataag accaagtttc ggcggtcttg ggctgcttct ggatgtgaat aggggtcata
    14281 ttggtttggt gcctgaggca ttccagccag caaggctaac tgaggtaaac ttaaattatt
    14341 gaggtcttta ccatagtagt tttgagctgc tgtctgcatt ccatagttcc cattagacat
    14401 gtagacctta tttatatagt aggtcaagat ttcttgcttg gttgcttttt gttctaactg
    14461 aatcgctaac caagcttcct gagccttacg agaaatagtc tggtcggaag tcgaagttga
    14521 aaagtaagtc aacttaatca actgttgggt gagagttgat ccaccttgga gggaattgct
    14581 ttgcagattg cgcaagaaag ctcccaggat acggatggta tcaatccccc tgtggtcgaa
    14641 gaagcgatgg tcttcgatag aaacgattgc cttaaccaaa tctgtgggaa tatcattagc
    14701 ttgggcattg acgcggcgtt cagaacccaa gtcagcaatg agttgatttt tattgtcgta
    14761 gattttacta gaagttgttg caactagttt actctcggat aggctaggag ccttgctaac
    14821 gtagtagaaa aaaactcctc cgcctaagac aatggctgcg ataaccaagc ttaagaagct
    14881 aatgttcaga tacttgatta ggcgcagaat cgttggtttg ttcatcttgt tttaccacct
    14941 aataaatgtt ctttgataac attgagataa ggaatttgag ggaaggcacc agccttgatt
    15001 tcatatccat attctcgaat atattcaagt ggcattgatt tttgtccctt atcttgatga
    15061 tagaagcgaa tcaaatcgaa tgccggcaat aagtaggttt cttgctgaga agaaaagtga
    15121 agaaggacaa agcagattcc ttgttgggca aggacttgtt ccatatgctg aatctgatgt
    15181 ggatgaaaat ttttcatcgg aatcgcacgt ttttgttttg tttccttgac ttcaaagtcg
    15241 atgtaatatc cattataaac gccagaatag tccgtcgttg aagcttgtcg aaaataggct
    15301 tcaacaatct tggcacgact tcgttgtgga tagtccactt gtacgatttg aataggagtt
    15361 ggtttcttat gtataacagc caagccctga gacaaatagt agtcgttggt agcattgatc
    15421 atcttttcaa aagacattcc tcgatttgcg aaatttttgg gttgagaaag agatgtttgt
    15481 cttttttgtg atgaaacttt atgtggatag ttgaccataa ttctccttat tggtacaata
    15541 acatcacttt attataccat aatttgcaca gaaagggtta aaaatggcta cagctttggt
    15601 tttaggctat tctgcttttg atttgggttt attttctgat aaggatcctc gtcttaaatt
    15661 gattaaaaaa gcgatacgta aagatttaga ggctatggca gcagatgggg tgtcttggct
    15721 tgtgtttaca gggactttgg gctttgaata ttgggtttta gaggttgctc aggagatgaa
    15781 aaccgaatac ggtttccagt tggccaccat ttttgctttt gaaacccatg gggaaaattg
    15841 gaatgaaggc aatcagatga aactgagtcg ctttaagcag gtagactttg tcaaatatgc
    15901 ctatcctcgc tatgaacaca aggggcagtt aagagattac cagcagtttt tgctggaaaa
    15961 cacgactagt tcctatcttt tttatgatga agaaaatgaa acaaaactag cttattttta
    16021 ccaaaagatg aaaaatcaag aggactattt tataaagaga ttaacatttg atgaattaaa
    16081 tgaacttgct gaaaattttt ccgaaaattg aagctttgac cttgattttt gtttgccttt
    16141 ttttatataa taatactagc aagcgagaat ggagagagac atggcaagta ttattttttc
    16201 agcgaaagat atttttgaac aagagtttgg acgtgaagtc cgtggctata ataaagtaga
    16261 agttgacgag tttttagacg atgtcatcaa ggactatgaa acctatgctg ccttggtcaa
    16321 gtcacttcgt caggaaattg cggatttgaa ggaagaatta actcgtaaac cgaaaccttc
    16381 accagttcaa gcagaacccc ttgaagcggc aattacaagt tctatgacga attttgatat
    16441 tttgaaacgc ctgaatagat tggaaaaaga agtttttggt aaacaaattt tagataactc
    16501 agatttttaa gtagttattt gagatgtgca atttttggat aatcgcgtga ggagaattgc
    16561 ttctcatgag gaaagtccat gctagcacag gctgtgatgc ctgtagtgtt tgtgctaggc
    16621 gaaaccataa gcctagggac gagaaatcgt tacggcagtt gaaatggcta agtccttgga
    16681 taggccagag taggcttgaa agtgccacag tgacggagtc tttctggaaa cagagagagt
    16741 ggaacgcggt aaacccctca agctagcaac ccaaattttg gtcggggcat ggagtacgcg
    16801 gaaacgaacg tagtattctg actgctatca gctagagctg ttagtggtag acagatgatt
    16861 atcgaaggaa gtggtcctag tcacttctgg aacaaaacat ggcttataga aaattgcata
    16921 taggttgggg ctgagaaatt ttctcaacct cattttttaa agtggacata tagaaaggtc
    16981 ttgcaagact gtaacatgaa aaaagaattt aatttaattg caactgtggc agcagggctt
    17041 gaggctgtcg ttggtcgtga agtgcgagag ttgggctacg attgtcaggt tgaaaatgga
    17101 cgtgttcgtt ttcaaggaga cgtgagagct attatcgaaa ccaacctttg gcttcgggca
    17161 gcagatcgta tcaaaattat cgtaggaacg ttcccagcta agacttttga agagctattt
    17221 cagggagttt tcgctttaga ttgggaaaat tatttaccac ttggagctcg gttcccgatt
    17281 tcaaaagcta aatgtgttaa gtccaaactt cacaatgagc ccagtgttca ggctatttct
    17341 aagaaagctg ttgtcaagaa attgcagaaa cactatgctc gcccagaagg ggttcctctg
    17401 atggagaatg gcccagagtt taagattgag gtctctattc tcaaagatgt ggcaactgtc
    17461 atgattgata cgaccgggtc tagcctcttt aaacgtggtt atcgtaccga aaaaggtggc
    17521 gctcctatca aggaaaatat ggcagcagcc attttacaac tttctaactg gtatccagac
    17581 aagcctttga ttgatccgac ctgtggttcg gggactttct gtattgaggc agttatgatt
    17641 gctagaaaga tggcgccagg tcttcgtcgc tcttttgcat ttgaggaatg gaactggatc
    17701 agcgatcgct tgattcaaga agtgcgcaca gaagcggcta aaaaagtaga ccgtgagctt
    17761 gagctggata tcatgggctg tgatattgat gctcgcatgg tggaaattgc taaggccaat
    17821 gctcaggtag ctggtgttgc aggagacatt acttttaagc agatgcgcgt gcaggattta
    17881 cgttccgata aaatcaatgg agtaatcatt tccaatccgc cttatggtga acgtttgtca
    17941 gatgatgcag gggtgaccaa gctctatgct gagatggggc aagtatttgc accgctgaaa
    18001 gcttggagca aatttatcct gactagtgat gaagcttttg aaagcaagta tggtagccaa
    18061 gcagataaga agcgtaagtt atacaacgga accttgaaag tggatctata tcaatatttt
    18121 ggtcagcgtg tcaaacggca agaggtaaaa tagaaaggga tactcatgag taaaaaaaga
    18181 cgaaatcgtc ataaaaaaga aggtcaagaa ccgcaatttg attttgatga agcaaaagag
    18241 ctaacagttg gtcaagctat tcgtaaaaat gaagaagtgg aagcaggagt cttgcctgag
    18301 gattccattt tggacaagta tgttaagcaa cacagagatg aaattgaggc ggataagttt
    18361 gcgactcgtc aatacaaaaa agaggagttc gttgaaactc agagtctgga tgatttaatt
    18421 caagagatgc gtgaggctgt agagaagtca gaagcttctt cggaggaagt tccatcttct
    18481 gaagacatct tactaccctt gcctctggac gatgaggagc aaggcttgga tcctctattg
    18541 ctagatgatg aaaatccaac agaaatgact gaagaagtgg aagaggagca aaacctttct
    18601 cgtctggatc aagaggactc agaaaagaaa agtaaaaaag gctttatttt gaccgttttg
    18661 gcgcttgtat cagtaattat ttgtgtcagt gcttattatg tctaccgtca agtggctcgt
    18721 tcgaccaagg aaattgaaac ttctcaatca actacagcca atcaatcgga tgtggatgat
    18781 tttaatacac tttatgacgc cttttacaca gatagcaata aaacggcttt gaaaaatagc
    18841 cagtttgata aactgagtca actcaaaacc ttgcttgata aactggaagg tagtcgtgaa
    18901 catacgcttg ccaaatctaa atatgatagt ctagcaacgc aaatcaaggc tattcaagat
    18961 gtcaatgcac aatttgaaaa atcagctatt gtggatggtg tgttggatac caatgccaaa
    19021 gccaaatcgg atgctaaatt tacagatatt aaaactggaa atacggagct tgataaagtg
    19081 ctagataagg ctatcagtct tggtaagagc cagcaaacaa gtacttctag ctcaagttca
    19141 agtcaaacta gcagctcaag ttcaagtcca gcaagctcaa atacgacaag tgagccaaaa
    19201 ccaagtagtt caaatgagac tagaagtagt cgcagtgaag tcaatatggg tctctcgagt
    19261 gcaggggttg ctgttcaaag aagtgccagt cgtgttgcct ataatcagtc tgctattgat
    19321 gatagtaata actctgcctg ggattttgcg gatggtgtct tggaacaaat tctagcaact
    19381 tcacgttcac gtggctatat cactggagac caatatatcc ttgaacgtgt caatatcgtt
    19441 aacggcaatg gttattacaa cctctataag ccagatggaa cctatctctt tacccttaac
    19501 tgtaagacag gatattttgt cggaaatggc gctggtcatg cggatgactt ggattactaa
    19561 gcagtcgtta caaaattctt tcttttcaaa agtaaaaatg ataaaataaa acaaatgaaa
    19621 caagaggagt gtcaaatgac aaaagctaac tttggtgttg taggtatggc cgtaatgggt
    19681 cgtaaccttg cccttaatat tgaatctcgt ggttacacag ttgctatcta caaccgtagt
    19741 aaagaaaaaa cggaagatgt gattgcttgc catcctgaaa agaattttgt accaagctat
    19801 gacgttgaaa gttttgtaaa ctcaatcgaa aaacctcgtc gtatcatgct gatggttcaa
    19861 gctggacctg gtacagatgc tactatccaa gcccttcttc cgcaccttga caagggtgat
    19921 atcttgattg atggaggaaa cactttctac aaagatacca tccgtcgtaa tgaagaattg
    19981 gcaaactcag gtatcaactt tatcggtact ggagtttctg gtggtgaaaa aggtgccctt
    20041 gaaggtcctt ctatcatgcc tggtggacaa aaagaggcct acgaattggt tgctgatgtt
    20101 cttgaagaaa tctcagctaa agcaccagaa gatggcaaac catgtgtgac ttatatcggt
    20161 cctgatggag ctggtcacta tgtgaaaatg gttcacaatg gtattgagta cggtgatatg
    20221 caattgatcg cagaaagcta tgacttgatg caacacttgc taggcctttc tgcagaggat
    20281 atggctgaaa tctttactga gtggaacaag ggtgaattag acagctactt gattgaaatc
    20341 acagctgata tcttgagtcg taaagacgat gaaggccaag atggaccaat cgtagactac
    20401 atccttgatg ctgcaggtaa caagggaact ggtaaatgga cgagccaatc atctcttgac
    20461 cttggtgtac cattgtcact gattactgag tcagtgtttg cacgcttcat ttcaacttac
    20521 aaagaagaac gtgtacatgc tagcaaggtg cttccaaaac cagctgcctt caactttgaa
    20581 ggagacaagg ctgaattgat tgaaaagatc cgtcaagccc tttacttctc aaaaatcatt
    20641 tcatacgcac aaggatttgc tcaattgcgt gtagcctcta aagaaaacaa ctggaacttg
    20701 ccatttgcag atatcgcatc tatctggcgt gatggctgta tcatccgttc tcgtttcttg
    20761 caaaagatta cagatgctta caaccgtgat gcagaccttg ccaaccttct tttggatgaa
    20821 tacttcttgg atgttactgc taagtaccaa caagcagtac gtgatatcgt agctcttgcg
    20881 gttcaagctg gtgtgccagt gccaactttc tcagcagcta ttacttactt tgatagctac
    20941 cgttcagctg accttccagc taacttgatc caagcacaac gtgactactt tggtgctcac
    21001 acttaccaac gtaaagacaa agaaggaacc ttccactact cttggtatga cgaaaaataa
    21061 gtaggtcagc catggggaaa cggattttat tacttgagaa agaacgaaat ctagctcatt
    21121 ttttaagttt ggaactccag aaagagcagt atcgggttga tctggtagag gaggggcaaa
    21181 aagccctctc catggctctt cagacagact atgatttgat tttattgaac gttaatctgg
    21241 gagatatgat ggctcaggat tttgcagaaa aattgagtcg aactaaacct gcctcagtca
    21301 tcatgatttt agatcattgg gaagacttgc aagaagagct ggaagttgtt cagcgttttg
    21361 cagtttcata catctataag ccagtcctca tcgaaaatct ggtagcgcgt atttcggcga
    21421 tcttccgagg tcgggacttc attgatcaac actgtagtct gatgaaagtt ccaaggacct
    21481 accgcaatct taggatagat gttgaacatc acacggttta tcgtggtgaa gagatgattg
    21541 ctctgacccg ccgtgagtat gaccttttgg cgacacttat gggaagcaag aaagtattga
    21601 ctcgtgagca attgttggaa agtgtttgga agtatgaaag tgcgaccgag acaaatatcg
    21661 tagatgtcta tatccgctat ctacggagca agcttgatgt taaaggccaa aaaagctaca
    21721 ttaaaactgt gcgtggtgtt ggatatacca tgcaagaata gaaggctctt tgtcaactgt
    21781 agtgggttga agtcagctaa gcttgagaaa ggacaaattt cgtcctttct tttttgatgt
    21841 tcagagcgat aaaaatccgt tttttgaagt tttcaaagtt tcgaaaacca aaggcattgc
    21901 gtttgataag tttgatgaga ttattggtcg cttccaattt ggcgtttgaa tagggtagtt
    21961 gaagggcgtt gacgattttc tctttgttct ttagaaaggt tttaaagaca gtctgaaaaa
    22021 taggatgaat ctgcttcaga ttgtcctcaa tgagtccgaa aaatttctca gggtctttgt
    22081 tctgaaagtg aaaaagtaag agttgataga tctgatagtg gtgtttcaag tcttctgaat
    22141 agcttaaaat cttgtcaaga atttctttat ttgttaagtg catgcgaaaa gtagggcgat
    22201 aaaaacgttt atcgctga
//
LOCUS       DAVLZS010000033        21294 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLZS010000033 DAVLZS010000000
VERSION     DAVLZS010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21294
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.033"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            256..438
                     /locus_tag="VYO88_001367"
     CDS             256..438
                     /locus_tag="VYO88_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1719454.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            383..1188
                     /locus_tag="VYO88_001368"
                     /pseudo
     CDS             383..1188
                     /locus_tag="VYO88_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1258..1620)
                     /locus_tag="VYO88_001369"
     CDS             complement(1258..1620)
                     /locus_tag="VYO88_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719455.1"
                     /translation="MPKTKTLAELADVILWGFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(1998..3878)
                     /locus_tag="VYO88_001370"
     CDS             complement(1998..3878)
                     /locus_tag="VYO88_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1719456.1"
                     /translation="MVRFTGLSSKQAQAIEVLKNHISLPDVEVAVTQSDQASISIKGE
                     GGHYQLTYRKPHQLYRSLSLLVTALAEADKVEIEEQAAYEDLAYMADCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKINTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(3872..4741)
                     /locus_tag="VYO88_001371"
     CDS             complement(3872..4741)
                     /locus_tag="VYO88_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1719457.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEENQW"
     gene            complement(4825..7470)
                     /locus_tag="VYO88_001372"
     CDS             complement(4825..7470)
                     /locus_tag="VYO88_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1719458.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPELL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELANIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILVDDTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VAATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(7561..8841)
                     /locus_tag="VYO88_001373"
     CDS             complement(7561..8841)
                     /locus_tag="VYO88_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1719459.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDSLLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            9012..11096
                     /locus_tag="VYO88_001374"
     CDS             9012..11096
                     /locus_tag="VYO88_001374"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1719460.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKQ
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKSSAQADWENLLHRFDIIEIGEADRTFFDHCLYRLFLFPQTF
                     YEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(11136..12815)
                     /locus_tag="VYO88_001375"
     CDS             complement(11136..12815)
                     /locus_tag="VYO88_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1719461.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQTGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            13571..14800
                     /gene="arcA"
                     /locus_tag="VYO88_001376"
     CDS             13571..14800
                     /gene="arcA"
                     /locus_tag="VYO88_001376"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV1719462.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            14858..15874
                     /gene="argF"
                     /locus_tag="VYO88_001377"
     CDS             14858..15874
                     /gene="argF"
                     /locus_tag="VYO88_001377"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1719463.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            16039..16986
                     /gene="arcC"
                     /locus_tag="VYO88_001378"
     CDS             16039..16986
                     /gene="arcC"
                     /locus_tag="VYO88_001378"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1719464.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVEADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            17197..18708
                     /locus_tag="VYO88_001379"
     CDS             17197..18708
                     /locus_tag="VYO88_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1719465.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            18730..20061
                     /locus_tag="VYO88_001380"
     CDS             18730..20061
                     /locus_tag="VYO88_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1719466.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLEFEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLVTQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(20541..20756)
                     /locus_tag="VYO88_001381"
     CDS             complement(20541..20756)
                     /locus_tag="VYO88_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719467.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGK"
     gene            complement(20744..20995)
                     /locus_tag="VYO88_001382"
     CDS             complement(20744..20995)
                     /locus_tag="VYO88_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1719468.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQATE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
BASE COUNT         6118 a         4721 c         4285 g         6170 t
ORIGIN      
        1 aatcattatc tagtagaata gagtagtaca ttttataaat tgtcatctct ccataaacac
       61 agtatatcat ttttaaattt taagtcaagg aaaattaacc cactttaatt tcttttttaa
      121 cccgtgttaa aaaagaaatt aaagtgggtt aaaaaagaaa ttaactgagt aaaaactctc
      181 gaaattcaat tcgctatatt atcactcaac ttgaacaaat accagaacca caaaaaacag
      241 atgtaaagga aaaatatgga cttaaaattt gaaggggttg atttagaata caaaaaagct
      301 aaaaacaatc ttccagagtc tttctgggaa acctactcag catttgcaaa tacaaatggc
      361 gggaaaataa ttctcgggat agatgaaaaa aacattgaca cctaccaaag agtcaataga
      421 ctccctgcga aattatgaag caagtaaaca actaaccgat gcacgattta agcgtcttgt
      481 tggtgttcag cgcaccactt ttgaagagat gttagctgtg ttaaaaacag cttatcaact
      541 taaacacgca aaaggtggac gaaaacctaa attaagccta gaagaccttc ttatggccac
      601 tcttcaatat gtgcgagaat accgcactta tgaagaaatt gcggctgatt ttggtattca
      661 cgaaagcaac ttaatccgtc ggagctaatg ggttgaagta actcttgttc aaagtggttt
      721 tacgatttca agaactcctc tcagttctga ggacacggta atgattgatg tgacggaagt
      781 aaaaagaaat gccacgctat gaaggctcag gcgattgtca caagtcaagg gagaattgtt
      841 tctttggata tcgctgtgaa ctattgtcat gatatgaagt tgttcaaaat gagtcgcaga
      901 aatatcggac aagctggtaa aatcttggct gacagtggtt attaaggact catgaagata
      961 tatcctcaag tacaaactcc acgtaaatcc agcaaactca agccgctaac agctgaagat
     1021 aaagcctgta accatgcgct atccaaggag agaagcaagg ttgagaacat ctttgccaaa
     1081 gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg ctttggatta
     1141 cgaatgaatt tgattgctgg tattatcaat catgaactag gattctagtt ttgcaggaag
     1201 tctattgaaa tactaagcct acacagactg attccaattg ttttttagat ttcaatttta
     1261 ccattcttca tagtcaaaac catcataatc tggatattgt tctggcgacg ttccaacaga
     1321 acgtacgaga taagcttctt cgtcctctgt ctcgatttct ctcagtactt ggcattcaaa
     1381 acgccattca tcaccgaagt cgaaaataaa cttaaatttt tgtttgacac ttaggctatc
     1441 cagatagaca ttttctgtgt aacgttcttc aacatcgtca ctaacaaagc taagaaagta
     1501 agaatctgca tgactccact caacattatc catgaaaaat gcgtgagcat gatcatttgc
     1561 aaaatcaaaa ccccataaaa tcacatctgc tagttccgct aacgtttttg tttttggaat
     1621 ctatatatgt cggtagcaac cttttttaaa tttgacggaa atgatccaag cttctacaga
     1681 tgctggcttt tcagcttcta tttcttgttt tactaatttt aagtgtagca taatacctcc
     1741 aattgctcat cgatagaatt gctcttagga aacattcact ttctgctatt ttatcataag
     1801 tttgtctaac tgtagcattt gaaaccagat aattcttctg tttcacgcga aacaccctgc
     1861 gccaagcaag gtgttcttgt ttttatactc aatgaaaatc aaagagcaaa ctaggaagct
     1921 agctgcaggc tgctcaaaac actgttttga ggttgtagat ggaagctgac gtggtttgaa
     1981 gagattttcg aagagtatta agtcgtataa atcgtcgacg ctgtcgcaat ggtatgccac
     2041 tggttagctg tagttgctgc gaagtccttg tctgcgtaga agtcagtaaa tggtaggatt
     2101 tcaacttcca gctcgtcgat gcggtcaagc tgaccagcca gataaacctc gatacggctt
     2161 tctgctcgtt tgatgcgttg caagagtccg cccatacgga tgtcaactgt atccaaacca
     2221 aagaccttgt tttctttcag ccattggtgg ctaaagaggg catggaagtc ttcaatttgg
     2281 cttctaagtt ctggtaattc ttgtctggcg atttgttgta aactttcttt atcatccgct
     2341 tggtaggcat gacgaatgcg tcgtcccaca tctactttgc tacttaaaat agcattcaac
     2401 tgggcctgag tttcaaagag ataagcatag tttccagctt tttctttaat gttagcaagc
     2461 gtctcagcag cctgagcgaa gtgcggtttg tcctgttcag gtgtcatgtg ttgatcaaga
     2521 atcggacaaa gaatatcctg ataaaaaaca tagcggttgg gattgatacc gctgagattg
     2581 cctggtaggt ctggtaagag gttggcaagg tcaatctgca taaaatcctc aaccgttaga
     2641 ccagtattga tcttgaagtg cgcagacaaa ccatctaggt cattgcgata gctgagttct
     2701 gcccagattt gcaagcttgg taggatagag aactgggcag tttcaccacc attgtctccc
     2761 caacccgtta cgatgacttc tttaatctga ttggcacggc aggctttatt agcctcgata
     2821 gccactagac ggctaaaatg gttgtgaggt gtaaagccaa tccacttcca agctccccct
     2881 gcaaatgcaa ggtcatggct aatcttgtga tgattgcgga aattacggtt gtatttttcc
     2941 tcgctatcct gataataatc ccagtaaacc agagtcacac ggtctttgag acggtctagg
     3001 tagacacgag tttcctctgg aatttccaca tcacggtcgt actggccatc cgctgacatg
     3061 agtttgaaga acatatcact ccacatctgg cagtggaaac catatttgtc agcaatatcc
     3121 agcacgcgct ccaagtgttg gcacatgagg agactacgat ccacaacacc gttcagaatc
     3181 aggtagcgtc ccaaaccaac caagtgggct tcgtccatcc cgatattgac cttgcgagtc
     3241 ttcagtttag acaacgtggc aaacatgcca tcaatcaggt cataaacctt ttcttcgcca
     3301 atgagaagaa tgtcctctac atcacggagc tcctgcactt ccttgacacc ccatttgaca
     3361 aaggccgaca agtgggccaa ggtctgaata caaggaacaa aagtcatgtc aaactgctgg
     3421 gcataggctt cgatttcctg caactcctca gccgaataag ccccgcggaa atagccaaag
     3481 taaggctgcc cttcaatctg gtaagtgtct tccatgtaga gctcaaaggt tgagtagccc
     3541 atgagagcca agacctctat catctgcttg gcagaagcca cattcagcac cgcatttcga
     3601 gaacagtctg ccatgtaggc taaatcttca taagctgcct gttcctcaat ctctacttta
     3661 tcagcttctg caagagctgt taccaacagg gacaaggaac gataaagttg gtgaggcttg
     3721 cggtaggtca attgatagtg gccaccctca cccttgatag agatagaggc ttggtcagac
     3781 tgagtaacag ccacttcaac atctggcaga gaaatgtgat tttttaatac ttcaatagct
     3841 tgcgcttgtt tggaactaag tcctgtaaat cttaccattg gttttcctcc tgtagccagt
     3901 tgacaagggc accgtagaga ttggcatctg cgtgataggt gcaggcctgg ataactggtg
     3961 cgaccgtgta ttcttcgtag gcatcgacaa agtcttcaac agccttctta acaccttgga
     4021 taaaatctgg attttgactg atagagccac ccagactgat gacatctgga tcgatgagat
     4081 actggatatt gagcaagcct tgcgtcagat tgcggttcat gcgctcaatg gcttcttgac
     4141 aaagagcatt accagctgcg gcctcttggt aaatcttgcg accgtcccaa tcagtatgac
     4201 cagatttttc aatcacgtat cgtaccatat tcccagttga tgctagttgc gaccagttat
     4261 taagtttttc agcaggggca agggttgtca tgtagccaaa ttctccaccc agaccgtggc
     4321 gacctcgatg aagtctacca ttgataatca tggctccgcc aatccctgtc ccaatcacga
     4381 cacaggctgc attttcaagc tctggatgag ctagtagttc actgagtcca acgcagttgg
     4441 catcattttc taaatggaca ggtagctgat aagagctaag cgcctcatac caagaaaagc
     4501 catggatata gggcaccgca ctgaagccat caatcacacc tgtctcttga ttgaccgcac
     4561 ctggaacgct catagcaatc ccactgtaat cctgttctga caagcgttga tctagccacg
     4621 ctagtaaatc ctccaagttt tcaggcgttg aaatacttgt cttatccagt attttcccat
     4681 caggagtcag actggcaaac ttaatcccag tccctccgat atcaatcgtt gcaatggtca
     4741 ttgtttttac cataaaaagg ggcgaatcag tagttagttc ttaccttttc gcccctcctt
     4801 tcttttgatg tttacttttt gaaattaaat ttcttctttt ttgatgaatt ctgtacgaat
     4861 ctcttgtgga gccaatagtc ctgaatgaac tggatatggt cgctcaagta agtcaagaat
     4921 ggtttgctga tgttctgata tgcgcacatt ttcttgactc atattatagt aacggaggac
     4981 atagccttct tcattttccg ccactttaaa ggctgttgga caaacttgcg gtatgctgag
     5041 aacagaatgg ctcaagaggc taccagtcgc agccacgctt ccttcctgtc tagcaagctg
     5101 aaggctggta aacggtgtct gcaaggcctt agctcgacga taagctgaga agcgttcttg
     5161 ggcttggtgg cactcaagcg caaactcgac ttcaaactcc cgcaagcatt gtgcttctgg
     5221 tgttgggaag tagccccagt cacctagctc acctgatgca cgcaaaatag tcactgcaat
     5281 ggtgtcgtct acaaggattt cgtattcatt caatcccttg ttggatacag tcacaccttt
     5341 ttcatcgtca tacagactaa caaaggcttg ttggtgttga ggattttcag gattttccca
     5401 tgaagcagct ggtttgtttg gtcgtgtcac cacctcatag atactttcag aatcattgct
     5461 tggacgcgtg ttatgagtct tgaccaagag acggatacgg tgatccttgg cagtgttagt
     5521 aaagcgagtc ttgaagcgga tttgtggatt gtcaacaaag acaatcaact cagtttccag
     5581 aggaatgttt gccaattctt ctgaccgtcc agcctcacgc ttcataaact cgatgatacc
     5641 ttgttgctct tcttctagct tttcatccgc gctgacaggc acggtcaatt catgtttgag
     5701 caagatttta gcatagcaag ctgtgttttc caagacctcg tggcccttaa gctctgcaaa
     5761 gattggctct gttccttttg gttggaaata gatatactcg tttccgatgt ccccacggtc
     5821 ttcaaagcgg ataaagtctt cataggcttc gtgagttgtc ttgtcataga ctgtgatgtt
     5881 gtcatccaca ctcaccgtta cgaatggtgt atcaatcact ccgttttggt aaataccctc
     5941 acggtgttct tgttttcctt ccagcaattg gaaggttgtc caagaaagcg gcgctaggtg
     6001 aactggaatg gtcacgcgca cttgacgagc aatacgagct tggcggaact tgtcttttgg
     6061 taaatcatac tcaaaattag ctccgaggtc ttcgattgta gcctctacag gacgaccatc
     6121 caagtcctcc acacggtaac ttggcaagat aagagcagcc atctttttgt agccttctgt
     6181 tgggtgcaat tccttgaaat cacaagtcgc cacatcaatc actgtgctga cagtatcgac
     6241 cttatcatgc aagcctgtgt taatgacagt aaagagatag tcactttgag ccttatccgt
     6301 agcaatttta cccttccact cgttgagcaa attactttta acaaagtttc ctacttggtt
     6361 gaccttggca aaacgcgttt ccatctcgcg gtgaacttcg tccacgctac agccacagat
     6421 actatcatgt ggcgcattct gcaaaagtgt tttccaagca taggtcaact ggtccttgtg
     6481 gttgtgtcca ccagtgataa tagtcaaggg ttctaccact tgctctagga ggttgctatt
     6541 ttcttggaag gcttgtttta ggtaaatgcg ggatgaagaa gtgttggcaa gtgtgtacca
     6601 gccatctgtt tcctgactgg tcaactcacc tgtaacagtt gataagagtt caggaagcgc
     6661 accttctaca gcttgaacat attcatcaaa agaactatga acaaagatta catccgggaa
     6721 gagttcattt gccacacgaa tggcttcgct cagatttttc tggacaggct ggtggtcaca
     6781 gccgttcatc atcaaccatt ggttggtcga agcgtaggca cgcacatctg acaatttttg
     6841 tttccagaag gtcaaggcct catctttgtc aactgggatt tcattcccat tactgtacca
     6901 gttggcaaag agaataccta aaacacgact accatccaca ccctgccagt acatttctga
     6961 aaactgggat gtaaactgct catcttcaag gacttggttg tcaaatccaa tcggcttcac
     7021 accacgacca aaggccgcca cgtgaatgcc tgatttttga agaatttgag gcgcttgtcc
     7081 catatttcca aaggtatctg gaaagtagcc aatctgggtt gatttacccc atttggcagc
     7141 ttcttgttga ccaatcaagg tattgcggac attggcttca ctggagatca agtagtcatc
     7201 ctgcaagatg taaaagggac caattttaag tttgccctcg tcaatgtagc gttggacctt
     7261 gtcacgattt tcagggcgaa tttgtaagta gtcgtcaagg acaatagttt gtccatccaa
     7321 gtggaaactc ttgaactcag ggtcattttc aaagagatca aagagattgt caaacaattc
     7381 caccaactgc atacgatggc tttcaaaagg caagtaccac tcacggtccc agtgactatg
     7441 tgagataata tgtacaacaa cattttccat gaagtaaaac ctcattctaa atttaaattt
     7501 taacgtttta aatgtaaact tgtgattctg ataagaatcg gttgagctaa agcgagcccc
     7561 ttagcgaata tccaagtaat ccaagaccaa ctcacagaac atcatgttag cccaggagaa
     7621 ccattcacga gagtagaggg tcggatcatc tacatgaaag ctttcgtgca tgacacctgt
     7681 accaccatcg caggcaacca gctgatccag caagaatttt ttctctgcct tatctcttgt
     7741 tgtcaatcct tggatagaaa gggcgattgg ccagatatag cgatagaagg tatgagaact
     7801 tccgagaccg ctagcgtatt ctccttggta gaaatatgga ttttcagagc tcaaaatggt
     7861 acgacgagta gcttgataca cttcatcatc gaccgaacag tagcccagat agggcgcagc
     7921 tagtagactt ggtacatttg gatcatccat gatgctggca tttcctaggc catccacttc
     7981 aaaagcgtaa atcttttcgc ccttgctgtt ggtggtgtaa gcgtagtttt tgattccttc
     8041 ttggatttca tcctgaagac gcttggcatc agcaataaca ctctggctat cagctaggtt
     8101 taatgctgcg aagatttctt gcacataacc caagactact acagcaaaca tatttgacgg
     8161 aatcaagtaa ctatactgac agcagtcatc gctcggacga aaggctgacc aagtcatacc
     8221 tgtcactgca aagtcaggtc caaagccatc atttaccaag gtgtcttcct tacggtccgt
     8281 atctcggaca aaacgataag gagagttctt gtggtcttgt tccaccgtcc acagatggag
     8341 aatttcctta gtcgctgcga caaaaatctc atcaaactga ctagtctcgc cagtctcttt
     8401 ccagaggaga taagccaact gcaaaggata gcaaagcgaa tccacctcat acttgcgctc
     8461 ccagatccag ccgttaaggt ctgtgtggtc agtctcgtgg tgccctttcc agttctcctc
     8521 aatgttgaag gagttagcat agggatcctt gagtaccaag gtcatctgac gtttgaccaa
     8581 acctgcaatg gtctgacgca ggagggaatc tcttttagcc acatgcaggt agggtctgag
     8641 ttgggctgtc gaatcccgaa gccacatagc aggaatatcc ccagtcaaga caaaagttga
     8701 accatcttct aagatttcaa ccgtattgtc caaggtatcg gtgtagcaac gctcgaaaac
     8761 atccacccac tctggatggt ccttagcccg ctctgctact tcatctagcc attctctaac
     8821 aatttctttc gaataaatca tcgtgcaatt ccctctttca aacaagtttc atgttcagta
     8881 tatagctttt gagacagaaa atacatacac aaatgatagt catttttcta caaaatagtt
     8941 atttttgaaa ctccttttct aaaggccctc tttttctgat ataatgtaga aaaacagcta
     9001 aaggaaagac tatgaaacca ctacttgaaa ccatcgatac ccgctttggt actgctagca
     9061 agcatgcctt ctctcgggga aataccctgc catacacagg cgtgcctttt gggatgaatt
     9121 actttgtgcc ccagaccagt gaccaggatg gatcttggtt ttttgatccg catctgccta
     9181 tctttcaggg gattcgatta actcaccagc ccagtccttg gattggggac tactcttggc
     9241 tccttctgac acctgtcacc agtcaactgg ggggagacag cctctttcac cgccagtctt
     9301 cttatgatat agataaagct tgcttccagc ctcactattt gaagctcttt tctctgcgtt
     9361 atcagattga aacccagctc acaccgactt gctatggtgc ttctattcgt ttgaatcaaa
     9421 agcaaggcaa agccctctcc ctctatcttc acgcagcaga tgaactgaca gtagagcaag
     9481 tagataagca gactcttgcc ctgcgacaag aaggtaaaac tgaaactaac aaaaattcgc
     9541 taacgatgtt cactgccctg caaatgaaca cggatattct tgctatcagc caagaagctg
     9601 gagactggcg aattgactta gcaagtagtc aaaccgagat gcaactagcc acttctttca
     9661 tctctccttc tcaagcactg cttaatctac ctcaagaaga ttttgatagc tgtaaatcaa
     9721 gtgcccaagc ggattgggaa aatctcctcc atcgttttga cattatagag ataggagagg
     9781 ctgaccgaac cttctttgac cactgcctct acagactctt cctcttccca cagacttttt
     9841 atgagattaa tgaatcaggg caagccatcc acatggatct ggctactggt actgtcaagc
     9901 ctggtgtcct ctttagcaac aatggtttct gggatacctt ccgcaccacc ttccccctct
     9961 ttgcccttat cataccggag cactatcaac gctttttaga aggtttcctc aatagctacc
    10021 gcgatactgg tttccttcca aaatggctgg ctccagatga acggggtatg atgccaggta
    10081 cacttttaga cggtattatc gcagatagcg cctgcaagga catgaccccc gacctagaag
    10141 gagaactctt ccaagccatg ctcaaaacag ccagcaaagc cgaccctctc ggcatcaatg
    10201 gccgccacgg actagcccaa taccaagaac taggttacct ctctaccgac caccacgaaa
    10261 gtgttagcca tactctagac tatgcctata gtgacttttg tatcgccagc tgtgccaaaa
    10321 aactagagaa catagaaatc gctgaaacct acaaggctgc ttcacaaaat taccgccagc
    10381 tatttgacgc tgagacaggt tacatgcgag cacgagacaa tcaaggaaac tttcaccctg
    10441 acttctctcc ttatagttgg gggcgagact acgctgaatg ctctgccatt caagctactt
    10501 taggcgttct ccacgacatc cctggcttaa tccaactgat gggtggaaaa gaaaccttta
    10561 gcaactatct tttgaaagcc tgtcaagatg ctcccctctt tgaaacaaca ggctatggtt
    10621 acgaaattca cgaaatgagc gagatggcta ctgctccttt tggacaaata gccatttcca
    10681 accagcctag tttccacatt ccttatctat tccgctacag cgattaccct gactacactg
    10741 cccttcttat caagacgctc cgtcagaaag cttttcaccc aagttgggaa gcctatcctg
    10801 gagatgaaga caatggtagt ctctctgctt ggtacatctg gtcagctctc ggattttatc
    10861 caacctgtcc aggaaaacca agctatgacc tcggaatccc tctctttgac catctacgag
    10921 tctacctcgc taaagaagat aaatggctgg atatccatac taaacaaaac cacaaccatt
    10981 ttaactttgt caaagaatgc cgactggaca aaacactcgt atcaactatt caacaccaag
    11041 acctcttaaa agctgaacaa ctaactttca ccctcagctg gttaccaagt cactaataac
    11101 caaaagaacc tttgcatcgc gcaaaggttc ttcttttatg aaacttggac ttgaagttga
    11161 tccacaagct gaccatccac cgttaggttc agatagaaat ccaaggtttt atctcctgcg
    11221 aaatacaagg ttggtagcgt cagacttttt tcagtctcac cagtttgaaa cgcaaggact
    11281 tgaatctcat cctgataggc gacaccatgg acacctgtcc ccggttgaat cgaaatctta
    11341 gcttctaaag aggagctact ttcactacgt tcaatcctaa aatgaagagt ctctcccttt
    11401 gccacagcta ggcttttttc tgcaaatgct agttcctgaa caacttcttt ttttgataac
    11461 ccaggagttt tataaaggga aatcttggtc aatacaggga tagattgtgc ctcggtaatc
    11521 atcacgcgca ccttttgtgc ctctactagc ggacctcgca agaggcgctt atgaccaact
    11581 gtgaagcccc tgccaaactc ctgccagaca ccatccacct ctacttgcac atggaaagca
    11641 gaaatacgtt ggcctaactt caaatcttct ctcaactcaa ttacatcaaa agttttagga
    11701 gaacctaagt cgagttctaa ctggatgggc aagtctgcat cgtttgccca agagctggtc
    11761 tcaaggccgt ctgtcaaatg gcgacaagca aagtctgcgg aaagagctgg accagatacc
    11821 tcagctccca gagccaaatc ttctttatag agctcattgc gataggtcgc aaattcataa
    11881 agtcgttcaa tatcctttgc atcaaagagc ccagcttgat tcggcggaat attaagcaag
    11941 agtggagttc ctcgccctac tgagtgaaag tagatttcga ccaactcctc gagagactta
    12001 ggatcctgat cctcatggta gaaccagcct ggacggatgg aaacatctgc ctctccgatt
    12061 gaaaaaatcg tgcccgaggg atccccgtgc tgaagatagt tcagctctgc ttctgttcct
    12121 agtttatcag gattcacctt ttgccacagt ggatcacctg cataccctcg ttcattgcca
    12181 atccagcgga tactggtgcc ttctgttgaa aaaatcaagc aatcgccctg caggtcacga
    12241 atggtttcaa accatttttc aaattcataa ttaacctttt gcgcgccctc tcctctggca
    12301 ccatccatcc aaacctcagc gaacttacca gcattcccat agttaggatt tgataagatt
    12361 tccttcaact gagccagata ataggcattg tagtccgctt ctcggtccac atgatagagg
    12421 ggactatggg catcccacgg tgacaggtag acccccatat ccatatcaaa ctctgtggca
    12481 gcttgggata cttcaaggag caagtcgccc tttcctctcc tccaaggact gaccttaacc
    12541 gaataatctg tgtgagctgt cggataaagg acaaagccat cgtggtgctt gaccaccaaa
    12601 atcaactttt tgaagcccgt ttccttgagc acacgaaccc actcacgcgc atccaactga
    12661 ctcgggttaa agcgctcagg atcctcctgt ccagtccccc attcttggtc ataaaaggta
    12721 ttaggaccga agtggataaa agctgctagt tcatctccca gataagctag ctgagtctga
    12781 cttggtaacg gtccatgcgg tttgattttc ttcatcgtta tatatctcct tctttagcaa
    12841 cttctcttgt tcacaaggtt atccacaggt tgtggataat aaaccatgat ctaacagcca
    12901 gctctttcca actccaactg gtaggctcag gatttttctc ctcaatattc cctcttcaaa
    12961 cagctctgtc atatgattct gctaacacct ctcagaatgc tactctccat aattattctc
    13021 aggcttcttt caggtcattg tgtgaagacc attcactctc cagacttttc cacagattgt
    13081 gaataagtga ttattctaaa ctatcacctc gtcgactata acaaaaaata aaaagagggt
    13141 caataagata attatctctt cctaaatact cagaaaagat tctataattt gtacaattga
    13201 acaagaaatg cttctccaaa atctatcttc aaaagaatgt tgcatctttt tatcctttca
    13261 cacaaacatt tctctttata cagatccaag tgataaccag atgataattg gacacttttt
    13321 ggtcatttgt atattttttg aaaaattttt taaaaaaatt ttatatcctt tttaatagaa
    13381 gtttatgcat ttgtatatat gtattatatc ctatgttgtg tataataaca taaaattgtg
    13441 ctaaatatca taatttatat tattttccga gaaattatag ccattgacat tacctaggaa
    13501 ttgcgttata acatacatgt aagcggtacc caaaatggtg ccaagtcaaa atttttaagg
    13561 aggaaaatac atgtcttcac atccaattca ggtcttctca gaaattggga aactgaaaaa
    13621 agttatgtta caccgtccag gcaaggagtt agaaaacttg ttgccggact atcttgaaag
    13681 gcttcttttt gatgatattc ctttcttgga agatgctcaa aaagaacatg atgcatttgc
    13741 ccaagctctt cgcgatgaag gaattgaggt tctctaccta gaacaactcg ctgctgaatc
    13801 attgacctct ccagaaatcc gcgatcaatt tatcgaagaa tacttagacg aagccaacat
    13861 ccgtgatcgt caaaccaagg ttgctattcg tgaattgctt cacggcatca aggacaacca
    13921 agaattggtt gaaaaaacaa tggctgggat tcaaaaagtt gaattgccag aaattcctga
    13981 cgaagctaaa gatctaactg acttagttga atcagattat ccatttgcaa ttgacccgat
    14041 gccaaacctc tatttcactc gcgacccatt tgcaacaatt ggaaacgccg tatcgcttaa
    14101 ccacatgttt gcagacactc gtaaccgtga aacactctac ggtaagtata tcttcaaata
    14161 ccacccaatc tatggcggaa aagtggattt ggtctacaac cgtgaagaag atacgcgtat
    14221 cgaaggtgga gacgagctag ttctttctaa agacgtcctt gcagtaggta tctctcaacg
    14281 tacagacgca gcttctatcg aaaaactttt ggtcaacatc ttcaagaaaa atgttggctt
    14341 caagaaagtt ttggcctttg aatttgctaa caaccgtaaa ttcatgcact tggatactgt
    14401 cttcactatg gtagactatg acaagttcac tattcaccca gaaatcgaag gcgaccttca
    14461 cgtttactca gttacttacg aaaacgaaaa acttaaaatc gttgaagaga aaggtgactt
    14521 agctgaactt cttgctcaaa accttggtgt agaaaaagtt catttgattc gttgcggtgg
    14581 tggcaatatc gtagcagctg cgcgtgaaca atggaacgac ggttctaaca ctttgaccat
    14641 cgcacctggt gtggtagttg tttatgaccg caataccgtg accaataaga ttttggaaga
    14701 atacgggctt cgcttgatta agattcgcgg aagtgaattg gttcggggcc gtggtggacc
    14761 tcgttgtatg tctatgccat ttgaacgtga agaagtgtaa tcgctgttcg gtattcgtca
    14821 atagaaaatg taaaaaatag aaagaggaaa taataaaatg acaaattcag tattccaagg
    14881 acgcagcttc ttagcagaaa aagactttac ccgtgcagag ttagaatacc ttattggtct
    14941 ttcagctcac ttgaaagatt tgaaaaaacg caatattcaa caccactacc ttgctggcaa
    15001 gaatatcgct ctcctatttg aaaaaacatc tactcgtact cgtgcagcct ttacaactgc
    15061 ggctatcgac cttggtgctc acccagaata cctcggagca aatgatattc agttgggtaa
    15121 aaaagaatct actgaagata ctgctaaagt attgggacgt atgtttgacg ggattgaatt
    15181 ccgcggattc agccaacgta tggttgaaga attggcagaa ttctcaggcg ttccagtatg
    15241 gaacggtcta actgacgaat ggcacccaac tcaaatgctc gctgactact tgactgttca
    15301 agaaaacttc ggtcgcttgg aaggcttgac attggtatac tgtggtgatg gacgtaacaa
    15361 cgttgccaac agcttgctcg taacaggtgc tatccttggt gtcaatgttc acatcttctc
    15421 accaaaagaa ctcttcccag aaaaagaaat cgttgaattg gcagaaggat ttgctaaaga
    15481 aagtggcgca catgttctca tcactgaaga tgctgatgaa gcagttaaag atgcagacgt
    15541 tctttacaca gacgtttggg tatcaatggg tgaagaagac aaattcgcag aacgtgtagc
    15601 tcttcttaaa ccttaccaag tcaatatgga cttagttaaa aaagcaggca atgaaaactt
    15661 gatcttccta cactgcttgc cagcattcca cgatactcac actgtttatg gtaaagacgt
    15721 tgctgaaaaa tttggtgtag aagaaatgga agtaacagac gaagtcttcc gcagcaagta
    15781 cgctcgccac ttcgatcaag cagaaaaccg tatgcacact atcaaagctg ttatggctgc
    15841 tacacttggt aacctttata ttcctaaagt ataattttag ataataaacc gtctaccaac
    15901 agctatgagg gctgcgacta atagctttag tccggtcctc ttttatataa tggtaatcta
    15961 ttatttctta taaaatatgt gaaaaatcat taaattgaaa tctaaacgca ttctattgag
    16021 tgtgataaag gagaatttat ggcaaatcgt aaaattgtag tagctttggg aggaaatgcg
    16081 attctttctt ctgacccatc agcaaaggct caacaagaag ctttagttga aacagctaag
    16141 catcttgtaa aattgattaa aaatggagat gatctgatta tcactcacgg taatggacct
    16201 caagttggga atctcttgct ccaacatttg gcatcagact ctgaaaagaa ccctgccttc
    16261 ccactcgact cacttgtcgc tatgacagaa ggtagcatcg gtttctggtt gaaaaatgct
    16321 ttgcaaaatg ctctcttgga tgaaggcatc gaaaaaaatg ttgcctctgt tgtaacgcaa
    16381 gttgtcgtag ataaaaatga tccagctttt gttaatttga gtaaaccaat cggtcctttc
    16441 tattcagaag aagaagcaaa agcagaagcc gaaaagagcg gagcgacttt caaggaagat
    16501 gctggccgtg gctggcgtaa ggtcgttgcc tcaccaaaac ctgttgacat caaagaaatt
    16561 gaaaccatcc gtactctttt aaatagtggt caagtcgtcg tagctgcagg tggtggcggt
    16621 attcccgtcg tcaaagaaaa caatggacat ttgactggtg tcgaagcggt tattgataaa
    16681 gacttcgctt cccaacgttt ggcagaattg gttgaggcag acctcttcat cgttttgaca
    16741 ggtgtagatt atgtatttgt taactacaac aagccaaacc aggaaaaatt ggaacatgtg
    16801 aatgttgccc agctggaaga atatatcaaa caagatcagt ttgcaccagg tagcatgctt
    16861 ccaaaagtag aagcagctat cgcttttgtc aatggtcgtc cagaaggaaa agcagttatt
    16921 acttcccttg aaaatctagg cgccttgatt gaatctgaaa gcggaacaat tattgaaaaa
    16981 ggataagttg ttttactaat aagatgtatt ctatttctag tatctttata tcaaattaga
    17041 aattattctt gaaaacatgt acaatatttc aaaagatatt agttttttag actttaatat
    17101 ggtaaaacaa atataaatag aaagcgtttt cttgaatgtt tatttaagaa agtagttggt
    17161 tttttacact ttgttagaca tcaggaggaa aaacaaatga gtgaaaaagc taaaaaaggg
    17221 tttaagatgc cttcatctta caccgtatta ttgataatca ttgctattat ggcagtgcta
    17281 acttggttta tccctgcggg ggcctttata gaaggtattt acgaggctca gcctcaaaat
    17341 ccacaaggga tttgggatgt cctcatggca ccgattcggg ctatgctagg tactcatcca
    17401 gaggaaggtt cgctcattaa agaaacgagc gcagcgattg atgtagcctt cttcatcctt
    17461 atggttggtg gtttccttgg cattgtcaac aaaactggtg ctcttgacgt agggattgcc
    17521 tctatcgtga agaagtataa gggccgcgaa aaaatgttaa ttttggtact gatgcctttg
    17581 tttgccctcg gtggtacaac ttatggtatg ggggaagaaa caatggcctt ctatccactc
    17641 cttgtgccag ttatgatggc cgttggtttt gatagcctga ctggtgttgc aattattttg
    17701 ctcggttctc aaatcggctg tttggcatct actctgaatc catttgcgac aggtattgct
    17761 tcagcgactg cgggagttgg tacaggggac ggtatcgtac ttcgtctgat cttctgggtt
    17821 accttgactg ctcttagtac ttggtttgtt taccgttatg cggataagat tcaaaaagat
    17881 ccgactaagt cactggttta tagtactcgc aaagaagatt tgaaacactt taacgtagaa
    17941 gaatcttcat ctgtagaatc tacacttagc agcaaacaaa aatcagttct cttcttattt
    18001 gtgttgacat tcatcttgat ggtattgagc ttcattccat ggacagacct tggcgttacc
    18061 atttttgatg actttaatgc ttggttgact ggtcttccag ttattggtaa tattgtcggt
    18121 tcatctactt ctgcactagg tacttggtac ttcccagaag gcgcaatgct ctttgccttt
    18181 atgggtatcc tgattggtgt tatttatggt cttaaagaag ataagattat ctcttccttc
    18241 atgaatggtg ctgctgactt gctcagtgtt gccttgatcg tagcgattgc tcgtggtatt
    18301 caagttatca tgaacgacgg tatgattacc gatacaatcc tcaactgggg taaagaaggc
    18361 ttgagcggtc tatcttcaca agtctttatc gttgtaactt atatcttcta tctacctatg
    18421 tcattcttga tcccatcttc atctggtctt gccagcgcaa ctatgggtat catggctcca
    18481 cttggagaat ttgtaaatgt ccgtcctagc ttgattatca ctgcttacca atctgcttca
    18541 ggtgtcttga acttgattgc accaacatct ggtattgtga tgggagctct tgcacttgga
    18601 cgtatcaaca ttggtacttg gtggaaattc atgggcaaac tcgtagtcgc tattattgta
    18661 gtgaccatcg cccttcttct ccttggaacc ttccttccat tcctataaaa tagtgagtga
    18721 ggtgattcca tgaaaataga tataacaaat caagttaaag atgaatttct tatatcatta
    18781 aaaaccttga tttcctatcc ttcagtactc aatgaaggag aaaatggaac accttttgga
    18841 caagcaatcc aagatgtcct agaaaaaact ttagagattt gtcgagacat aggtttcact
    18901 acctatcttg accctaaagg ttattacgga tatgcagaaa tcggtcaggg agcagagctt
    18961 ctggccattc tctgtcattt ggatgttgtt ccatcaggtg atgaagcaga ttggcagaca
    19021 ccgccatttg aagcaactat caaagacggc tgggtattcg gacgtggtgt ccaagatgat
    19081 aaaggccctt cgctcgcagc tctctatgca gtaaaaagct tgctggacca aggtattcag
    19141 ttcaaaaagc gcgtacgctt tatctttggt accgatgagg aaaccctctg gcgctgcatg
    19201 gcacgctaca ataccatcga agaacaggcc agtatgggct ttgcacctga ctcatctttt
    19261 cctctgacct atgctgaaaa agggcttcta caggtcaaac ttcatggccc tggatcggat
    19321 caactagagt ttgaagtagg aggcgccttt aacgttgtac cagacaaggc caactaccaa
    19381 ggtctcctct atgaacaggt ttgtaacggt ctcaaagaag ctggttatga ttaccaaacc
    19441 actgaacaaa ccgtaacggt tctcggagtg ccaaagcatg ctaaggatgc tagtcaaggt
    19501 atcaatgctg tcatccgact agctaccatt cttgctcctc tccaagaaca ccctgctctc
    19561 agttttcttg taacacaagc aggtcaagac ggcacaggaa gacaaatctt tggtgatata
    19621 gcagatgaac cttctggtca cctatccttt aatgtcgcag gtctcatgat caatcatgaa
    19681 cgttctgaaa tccgtattga cattcggact cctgtcttag ctgacaagga agaactagta
    19741 gagttgctta caagatgtgc acaaaactac caactccgct acgaagagtt tgactatcta
    19801 gcgcctctat acgtcgcaaa agacagtaaa ctcgttagca cactgatgca aatctaccaa
    19861 gaaaagactg gcgataacag tcctgctatt tcatccggtg gtgccacttt tgctcgcacc
    19921 atgccaaatt gtgtagcctt cggcgcctta ttcccaggag cgaagcagac agaacatcag
    19981 gcaaatgaat gtgccgttct agaagatttg taccgtgcta tggatattta tgccgaagcc
    20041 gtctatcgac ttgcaactta atcaggcaac tgtttctaca aaaaaaaatc gaccgattaa
    20101 tgaactgcac cccaaaagtt agacagaata aatctaactt ttggggtgtt ttattatgaa
    20161 attgaattat gaagataaag ttcagatcta tgaactaaga aagtaagaac aaagcttcaa
    20221 acagctttca aaaagattta tgtggatgtt tctggtttaa agtcatctga atctttgaga
    20281 tgagctttat aaatcgcttt tttcagtttt tgcactggta tttcgataaa ctcaaacttt
    20341 ttagccgttg tattgcctga ttttatagta tgttgaaact agaatagtac acctctactt
    20401 ctaaaacatt tttagaaatc gatttgattg tcctgattga tttgtcctgt tcttatttca
    20461 ttttattata tttgagccac ttcatcttta acggctttat tcataagctc ttgtaatttt
    20521 tctttactat caattacttc ttattttccg ttgtaattta ttgtaatagg ttttaactta
    20581 cctaatttct cgacacgctc attaatttga tcttttttga aggctgcata tgtttttcct
    20641 aagatttttt cgaaaatata tttatcagat agcggtttgc cttcttcttc agcttggttt
    20701 ttgtattgat ttgaaacata aggaacaaat ccttcatagt aacctaatgc tcccataagt
    20761 tcaaaagctt gttttctaat tcaaaccatt gcaactcaga tttcagcttt tcagataaat
    20821 cctgctcatc caaataatga cttgaaatta gtgctgaact cgtttctgta gcctgtacag
    20881 gctgagcacc cataccagca aaaaataaac tcgttcctag caagaccgaa caagctccta
    20941 ttgcatattt cctcaaagaa aaacgctgct ttctctcaaa ttgaaattct ttcatcccat
    21001 ctcccatcat tcattattac tgtatatttt gtatatcaga aatagtttgt attcacaaat
    21061 ctttctagtt attcccttat cattcctaat taagggagat aacatacaat aatttttagt
    21121 taaatgtata tcgatgtttt ttgtttttct taataaacgc aatacaaaaa gagcctgtta
    21181 ccaagctctt tgtactcaat gaaaatcaaa gagcaaacta ggaaactagc cacaggttgc
    21241 tcaaaacacc gttttgaggt agtagataag actgacgaag tcagctcaaa acac
//
LOCUS       DAVLZS010000034        21030 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLZS010000034 DAVLZS010000000
VERSION     DAVLZS010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.034"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            567..950
                     /locus_tag="VYO88_001383"
     CDS             567..950
                     /locus_tag="VYO88_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1719469.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVFYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            1002..1691
                     /locus_tag="VYO88_001384"
     CDS             1002..1691
                     /locus_tag="VYO88_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1719470.1"
                     /translation="MKKYQLLFKTSAILSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1733..1966
                     /locus_tag="VYO88_001385"
     CDS             1733..1966
                     /locus_tag="VYO88_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719471.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            2117..2728
                     /locus_tag="VYO88_001386"
     CDS             2117..2728
                     /locus_tag="VYO88_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1719472.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSF
                     LVTSLSVAYARKFEMISFGMLSKKELLLFIAIFLLSVLETLVYIHFFAISSGAGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLTYL"
     gene            2890..3684
                     /locus_tag="VYO88_001387"
     CDS             2890..3684
                     /locus_tag="VYO88_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1719473.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGRYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQKTAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3681..4316
                     /gene="trmB"
                     /locus_tag="VYO88_001388"
     CDS             3681..4316
                     /gene="trmB"
                     /locus_tag="VYO88_001388"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1719474.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4442..4921
                     /gene="rimP"
                     /locus_tag="VYO88_001389"
     CDS             4442..4921
                     /gene="rimP"
                     /locus_tag="VYO88_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1719475.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            4965..6101
                     /gene="nusA"
                     /locus_tag="VYO88_001390"
     CDS             4965..6101
                     /gene="nusA"
                     /locus_tag="VYO88_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1719476.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6123..6416
                     /locus_tag="VYO88_001391"
     CDS             6123..6416
                     /locus_tag="VYO88_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1719477.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6409..6708
                     /locus_tag="VYO88_001392"
     CDS             6409..6708
                     /locus_tag="VYO88_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1719478.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6725..9517
                     /gene="infB"
                     /locus_tag="VYO88_001393"
     CDS             6725..9517
                     /gene="infB"
                     /locus_tag="VYO88_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1719479.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9768..10118
                     /gene="rbfA"
                     /locus_tag="VYO88_001394"
     CDS             9768..10118
                     /gene="rbfA"
                     /locus_tag="VYO88_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1719480.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKVQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            10397..11180
                     /locus_tag="VYO88_001395"
                     /pseudo
     CDS             10397..11180
                     /locus_tag="VYO88_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11182..11364
                     /locus_tag="VYO88_001396"
     CDS             11182..11364
                     /locus_tag="VYO88_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719481.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            11361..11501
                     /locus_tag="VYO88_001397"
     CDS             11361..11501
                     /locus_tag="VYO88_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719482.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            11769..12002
                     /locus_tag="VYO88_001398"
     CDS             11769..12002
                     /locus_tag="VYO88_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1719483.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            12002..13336
                     /locus_tag="VYO88_001399"
     CDS             12002..13336
                     /locus_tag="VYO88_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1719484.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKDVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKRLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            13346..13600
                     /locus_tag="VYO88_001400"
     CDS             13346..13600
                     /locus_tag="VYO88_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1719485.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            13696..14091
                     /locus_tag="VYO88_001401"
     CDS             13696..14091
                     /locus_tag="VYO88_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1719486.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQDQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            14371..14931
                     /locus_tag="VYO88_001402"
     CDS             14371..14931
                     /locus_tag="VYO88_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719487.1"
                     /translation="MTRAELPDKIETERLVLRVRTVADAEDIFDYASRPEVSYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKELNLHKIELSCFGYNFQSQRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLRSEWEGI"
     gene            14931..15509
                     /locus_tag="VYO88_001403"
     CDS             14931..15509
                     /locus_tag="VYO88_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1719488.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLLYLKQIQDLLDDYHQEI
                     LFVELETSLEERIRRNRTENRLKHKPLKQHIEVSEREILDTAETLQLNSQHQPNELHH
                     YLKINNTNLSAEEVAKQIQDKMNTIEKGHTYI"
     gene            15754..16995
                     /locus_tag="VYO88_001404"
     CDS             15754..16995
                     /locus_tag="VYO88_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719489.1"
                     /translation="MAKKKNRKKELKRQQKLDIKVISEEEAAWTEIMAKNPTFVERRT
                     IQNFDELHTAVMQYADEYGKYPDVQLINYQLKNRTFDWKQDHAIFREAMHTPNTQKRN
                     KLLKQVLKINPDYFAADFHLFLSEVEDFDLSTFKKVLDFELLVLEKWKMNGYNSWNYF
                     EARPILSALMFLIEYYMMENFNSKAIELIDLYLSKRPERFPPNFVFCMLSLYHITGQE
                     LKVERFYREELNKGKRDDTILIHAIISAFSQGKIEEASQLFAKLVEINDEAVEFFIEE
                     DWQFKVIDIEDRECYCPNSVESLQASLYPLFDYLLENIILTKFLTNESKKFRRKPVFS
                     NHSGMIRNLSEVSDWHSFMNEEKMKGIRMDLVHIFVENGIRTSSDFKKWTEKEVLALK
                     GIGPVTVKKLKENGIKFKNEK"
     gene            17026..18027
                     /locus_tag="VYO88_001405"
     CDS             17026..18027
                     /locus_tag="VYO88_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HEV1719490.1"
                     /translation="MNEISNFILYTTPNGHVQLDILLQDENLWLTQKGLAELFGVERS
                     VITKHLKNIYDSGELDKVSTCAKFAQVQQEGNRAVRRELEYYNLDAIISVGYRVNSSK
                     ATQFRIWATKTLKEFIIKGFVLDDERLEQGQTVFGQDYFRELLERIRSIRSSERRIYQ
                     QITDIFAECAIDYDQNSDITKNFYAMVQNKFHYAITGSTAAEIIYQQADASREKMGLT
                     SWKNAPDGRVLKSDVTVAKNYLQEKEIRQLERTVTAYFDYIEGLVERRNTFTMRGLAD
                     SIDRFLSFNEYEILEGKGSISKKQADSKAIQEYEKFNRTQKILSDFDKHILKIMRES"
     gene            18149..20800
                     /locus_tag="VYO88_001406"
     CDS             18149..20800
                     /locus_tag="VYO88_001406"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1719491.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGREKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNDLAFEFAGMDRFEARKAVVAKLEEIGALV
                     KIEKLVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGEGWTQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFKRYYPTSTLVTGYDIIPFWVSRMIFQGLEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQATANVEKVVNKEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASNIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
BASE COUNT         6502 a         3855 c         4710 g         5963 t
ORIGIN      
        1 ttttaaaaaa caatgatata ctaaacttgt caaagttgca acgggtgctg ctacattatg
       61 ttaaaaatcg ctcttgattg ataagctgga tttgttagga aaggagtaaa taattatgga
      121 taagaaaaag atagtttcga ctataatatg tatagtattt cttgtagtgt cagtagataa
      181 tttttttaga gacttaaccc cgttactgtt cattttaaat attattggcc tgtcttgctt
      241 ttcagtgcta acatacatta acataaaaga gatactctta aatataagta aatgatgatt
      301 tggttagtcc tagaaccaat caacttatgt ttatcggctt ggcagatttt atgtttgtca
      361 tttgtttgta tagaggtatt tcagaaacag aattctatca acaactaatc gcttatatag
      421 gtgtattctc tgcttgttta tcacgcttct gctcatgtgg ggcttgaagt attataaaaa
      481 gtagctttct atccttttct gacaggatat ttgagtagaa ggctctatta aattgttagt
      541 gaaataaatg aatggaggta tttaatatga aatacagatt attttttgtt attttcttga
      601 gtagtgtgtt ggatattctt ttagggacat ttttacaaat ctctatcgta tctattgggt
      661 ggcttgtttt ttacagtggt ttgtttgaag caggagtttt ccttcttgct aataaagggg
      721 tggcggtaaa aatcaaggaa gtagatattc gaaatcgctt taaatttatt tttggaaaaa
      781 ccttatggtt tcaaattctt ttgctcatct ttttgataat caaactttat cttggtttgg
      841 atgcgaggtt gattttattc tatggacata ttttcattgt ctttaatgcc ttaatgtatc
      901 tattatctag tagtcaggtt agccttaaaa aaaacaaact gtcttcttaa tcttacagca
      961 gtagagcctg acaaggtgag gtcatagtag ggaggatttc tatgaaaaag tatcagcttc
     1021 tattcaaaac aagtgcaatt ttatcctacc tatttttcgt atttggtctt tctcagctga
     1081 cgcttatcgt ccaaaactat tggcaatttt cttctcagat aggcaattta ttctggattc
     1141 aaaatatctt gagtttactt tttattggag tcatgattgt ggttcttgtt aagacaggcc
     1201 atggttatct cttccgcatt ccaagaaaaa aatggctttg gtattcgatt ttgacagtat
     1261 tagtggtagt gttccagatc tcttttaacg ttcagacagc taaacatgtt cagtcaactg
     1321 cggaaggttg ggctgtattg attggttata gtgggactaa ctttgcagag ctaggtattt
     1381 atatagccct gttctttctg gttccactga tggaagaatt gatttataga ggactactgc
     1441 aacatgcttt ctttaagcat tcgcgatttg gtcttgattt gcttcttcct tctattttat
     1501 ttgctctccc tcatttttca agcctgccta gtctgttaga tatcttcgtc tttgcaacag
     1561 ttggaatcat ctttgctggt ttgacccgct ataccaagag catttatcca tcctatgcgg
     1621 tgcatgtgat caataatatt gtagcgacct tcccgttttt gctcactttt ctacataggg
     1681 tcttggggta aaaaaacaaa aggcttgctt ttcagccata gaggaggtca tcatgtataa
     1741 acacttattt ttcctagatt ccaaaacttt agatcggttg acaccctata ttctagtctt
     1801 ggcttctgac accattgctt ttaatgtttt tgtgctaacc tttgtatctg cggtggtttt
     1861 taatttccta aattccatgc tagctttaat ggctatattc ataggggctg gctatgtggt
     1921 cggattttgg ttactaatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag
     1981 gctgtacttg agtacggcaa ggcgacgttg acgtggtttg aatttgattt tcgaagagta
     2041 taaaatggtt tgttttggaa aggctagaac taaaggatga cgcgtaggaa gtctgtttgg
     2101 tgaggaggat agttttatgg agttttttga taaatttcat gccttatgct ttggattttt
     2161 agtactaata atcgttatta cagttcctta tacgattaac catggggatt tttttcaaaa
     2221 tgaatctgca ttgattattg taagttttct tgtaacctcg ctgagtgttg cttatgctag
     2281 aaaatttgaa atgatttctt ttgggatgtt aagcaagaaa gagcttttgc ttttcattgc
     2341 aatctttctt ctaagtgtgc ttgagacgct ggtttatatt catttcttcg ctatttcttc
     2401 tggcgcagga gttcaacact tggcggaagt cagcagagga atttctctgt ctttgatttt
     2461 gactacctca gtttttggcc ccatccagga ggaactcatt ttcagaggac ttcttcaagg
     2521 tgcggttttt gacaactctt ggttagggct tgtgctaact tcctctctct tttctttcat
     2581 gcatggacct tctaatgtac cttcgtttat tttttatcta cttgggggct tgttactggg
     2641 ctttgcttat aaaaagagcc aaaatttgtg ggtttctact ctagtccaca tgttttacaa
     2701 cagttggcca ctcttaactt atttataaaa atcatgaaaa ggtaagtagg agattgtgct
     2761 tacctttttc tttctataat gatactcaag ccaatccaga ggcttttatt tgagaatcgg
     2821 gtgtggagcg gttgacgaat aggccaaaaa ctagtagaat agtaaggaaa ctttatacgg
     2881 aggaaagaaa tggatttggg tgataatgag ctaacactga ctcccatacc tgggaaaagt
     2941 ggcaaggctt atatgggtag atatcctgat gggaagcgta tctttgtaaa aatgaacacc
     3001 tctccaatcc tacctggtct agctagagaa caaattgctc cacaattatt atggagtcgt
     3061 cgtttggcag atgggcgtga tatgtgtgct caagaatggt tgacaggaaa gatattgacc
     3121 ccctatgata tgaatcgtaa gcaaatcgtc aatattttaa cccgtcttca tcgctcacgt
     3181 ccgttgatga cacaattgag tcgtttgggc tatgccatgg aaacacctgt agatttacta
     3241 cagtcttggc aaaaaacggc tccagatgct ttgcgtaaaa atcattttat cagtgaagtg
     3301 atggctgatt tacgtcagac tattccagga tttagagagg accatgcgac cattgtccat
     3361 ggagatgtac gacatagtaa ttggattgag acagatagtg gcttgattta tttagtagat
     3421 tgggattcgg ttcgcttgac cgatcgcatg tttgatgtgg cccatatgct ctgccattat
     3481 atttcagaac atcagtggaa ggaatggttg acctactacg gttacaagta caatcaaacg
     3541 gtattaagta aattgtattg gtatggtcaa ttgtcttatt tgagtcagat ttccaagtat
     3601 tatatgaacc aagatttaga aaatgtcaat cgggagattc atggtttgcg tcatttccga
     3661 gacaagtatg gaaagagaag atgagagtta gaaatcgtaa aggggcaaca gaattactag
     3721 aggcaaatcc ccagtatgtg gtcctcaatc ccttggaagc caaggcaaaa tggcgggact
     3781 tgtttggcaa tgataatccc attcatgtgg aagttggaag tggaaagggt gcctttgttt
     3841 caggtatggc caagcaaaac cctgacatca actatatcgg gattgatatt caaaagtctg
     3901 ttttgagcta cgctttggac aaggtgcttg aagctggagt gtctaacatc aagctcttgt
     3961 gggtagatgg ttctgacttg actgactatt ttgaagacgg tgagattgat cgcttgtatc
     4021 tgaacttttc agatccatgg ccgaaaaaac gccatgaaaa gcgtcgtttg acctacaaga
     4081 cctttttgga taccttcaaa cgtatcttgc ctgaaaatgg agaaattcat ttcaagacgg
     4141 ataaccgtgg cttgtttgag tacagtttag tgagcttttc tcaatatggc atgaaactca
     4201 atggtgtctg gctagatttg catgccagtg attttgaagg caatgtcatg acagaatacg
     4261 agcaaaaatt ctcaaacaag gggcaagtta tctaccgagt tgaggcagaa ttttaagaga
     4321 tagcctaaaa ttaggctgta caagtgcttt tgctttacat aagttggcaa acgtgctata
     4381 ctgatagtaa gaatatgaaa agtgaggcgg ggaaatatct tcgcctcttg cttatgagga
     4441 ggtggacgca atcgcaacaa tcgtagaatt agtcagagaa gttgtagaac ctgtcataga
     4501 agctcctttt gaactcgtgg atatcgagta tggaaagatt ggcagtgaca tgattctcag
     4561 tatttttgta gataaacccg aaggaattac cttgaacgac acggcagact taacagaaat
     4621 gatcagtcct gtcctagaca ccatcaagcc agatcccttc ccagaacaat atttcctaga
     4681 aattaccagt ccaggcttgg aacgtccttt gaaaaccaag gatgccgtcg ctggagcggt
     4741 tggaaaatac atccatgtcg ggctctacca agccatcgat aagcaaaagg tctttgaagg
     4801 aaccttgttg gccttcgaag aggacgagtt gactatggaa tatatggaca agacgcgtaa
     4861 gaaaaccgtc caaattccat acagtttagt atcaaaagca cgtttagcag ttaaattata
     4921 gaaaaagaaa ggatagcttt tgaggattca aaagtgaaga aaacatgagt aaagaaatgc
     4981 tagaggcctt ccgcattttg gaagaagaca agggaatcaa aaaagaagat atcatcgacg
     5041 cagtagtaga gtcgcttcgt tccgcttatc gcagacgcta tggtcagtca gacagcgtag
     5101 ctattgactt caacgaaaaa acaggtgact ttacagttta tactgtccgt gaagttgttg
     5161 atgaagtatt tgatagccgt ttggaaatca gcttgaaaga tgctcttgcc attaattcag
     5221 cttatgaact tggagacaaa atcaagtttg aagaagcacc agctgagttt ggtcgtgtag
     5281 cagcccaatc tgccaaacaa accatcatgg aaaaaatgcg caagcaaaca cgtgccatca
     5341 cttacaatac ttacaaagaa catgagcaag aaatcatgtc tggtacagta gaacgctttg
     5401 acaaccgctt tatctatgtc aaccttggta gtatcgaagc ccaattgtca aaacaagacc
     5461 aaattcctgg agaagttttt gcttctcatg atcgtatcga agtttatgtt tacaaggttg
     5521 aagacaaccc tcgtggtgtg aacgtctttg ttagccgtag ccatccagaa atgatcaaac
     5581 gtttgatgga gcaagaaatt ccagaagttt atgatggaac tgttgaaatc atgagcgtgg
     5641 ctcgtgaagc aggtgaccgt acgaaggttg ctgttcgtag ccacaatcca aacgtggatg
     5701 ctatcggtac aatcgttgga cgtggtggtg ctaatatcaa gaagattact agcaaattcc
     5761 acccagctcg ttacgatgct aaaaatgacc gcatggtacc aatcgaagaa aatatcgatg
     5821 ttatcgagtg ggtagcagat ccagctgaat ttatctacaa tgccatcgct cctgctgagg
     5881 ttgaccaagt tatctttgat gaaaacgaca gcaaacgtgc cttggtggtt gttccagata
     5941 acaagctttc tcttgccatt ggtcgtcgtg gacaaaacgt gcgcttggcg gctcacttga
     6001 ctggttaccg tatcgatatc aagtctgcta gcgaatttga agccatggaa gacgctgctt
     6061 cagtagagtt ggaagtagaa aacgatactg tagaagaata aaagctgcta gaggagggaa
     6121 agatgaaaac aagaaaaatc cctttgcgca agtctgttgt gtctaacgaa gtgattgata
     6181 agcgtgattt gctccgcatt gtcaagaaca aggaaggaca agtctttatt gatcctacgg
     6241 gcaaggccaa tggccgcggc gcttatatca aactagacaa tgcagaagcc ctagaggcga
     6301 aaaagaagaa ggtctttaac cgcagcttta gcatggaagt ggaagaaagc ttttatgacg
     6361 agttgatcgc ttatgtggat cacaaagtga aaagaagaga gttgggactt gaataagcaa
     6421 aagataagta atctcttggg gcttgctcag cgagcagggc gcatcatatc gggtgaagaa
     6481 ttggtggtca aggccattca agacggcaag gccaagttgg tctttctagc tcatgatgct
     6541 ggacccaatc tgaccaagaa gattcaagat aaaagtcatt attatcaagt agaaattgta
     6601 accgtgtttt caacactgga attaagcata gcagtcggga aatcgagaaa ggttttggct
     6661 gtaacagatg ctggatttac aaagaaaatg aggtctctta tggaatagaa gaggaggaca
     6721 tgatttgtct aagaaaagat tgtacgaaat cgcaaaagaa cttggaaaag aaagtaaaga
     6781 agttgtagcg cgtgcaaaag agttaggctt ggatgtgaaa agccactcat caagtgtgga
     6841 agaagctgtc gctgcaaaaa ttgctgccag ctttaagcct gcagctgctc cgaaagtaga
     6901 agcaaaacct gcagcaccaa aagtaagtgc agaaaagaaa gccgaaaaat ctgagccagc
     6961 taaaccagct gtagctaagg aagaggcaaa accggctgag ccagttgctc cgaaaacaga
     7021 aaaagtagca gtgaaaccgc aaagtcgtaa tttcaaggct gagcgtgaag cccgtgctaa
     7081 agagcaggca gaacgacgca agcaaaataa gggcaataac cgtgaccaac aacaaaacgg
     7141 aaaccgtcag aaaaacgacg gccgtaatgg tggaaaacaa ggtcaaagca accgcgacaa
     7201 tcgtcgcttt aatgaccaag ctaagaagca gcaaggtcag caaaaacgta gaaatgagcg
     7261 ccgtcagcaa gaggataaac gttcaaatca agcggctcca cgtattgact ttaaagcccg
     7321 tgcagcagcc ctaaaagcag agcaaaatgc agagtacgct cgttcaagtg aggaacgctt
     7381 caagcagtat caggctgcta aagaagcctt ggctcaagct aacaaacgca aggaaccaga
     7441 ggaaatcttt gaagaagcgg ctaagttagc tgaacaagca cagcaagttc aagcagtggt
     7501 tgaagtcgtc cctgagaaaa aagaacctgc agtggataca cgtcgtaaaa aacaagctcg
     7561 accagacaaa aatcgtgacg attatgatca tgaagaagat ggtcctagaa aacaacaaaa
     7621 gaatcgaagt agtcaaaatc aagtgagaaa tcaaaagaat agtaactgga ataacaacaa
     7681 aaagaacaaa aaaggcaata acaagaacaa ccgtaatcag actccaaaac ctgttacgga
     7741 gcgtaaattc catgaattgc caacagaatt tgaatataca gatggtatga ccgttgcgga
     7801 aatcgcaaaa cgtatcaaac gtgaaccagc tgaaattgtt aagaaacttt tcatgatggg
     7861 tgtcatggcc acacaaaacc aatccttgga tggggaaaca attgaactcc tcatggtgga
     7921 ttacggtatc gaagcaaaac aaaaggttga agtggataat gctgacatcg aacgtttctt
     7981 tgtcgaagat ggttatctca atgaagatga attggttgag cgtccaccag ttgttactat
     8041 catgggacac gttgaccacg gtaaaacaac ccttttggat actcttcgta actcacgtgt
     8101 tgcgacaggt gaagcaggtg gtattactca gcatatcggt gcctaccaaa tcgtggaaaa
     8161 tggtaagaag attaccttcc ttgatacacc aggacacgcg gcctttacat caatgcgtgc
     8221 gcgtggtgct tctgttaccg atattacgat cttggtcgta gcggcagatg acggggttat
     8281 gcctcagact attgaagcca tcaaccactc aaaagcagct aacgttccaa tcatcgtagc
     8341 cattaacaag attgataaac caggtgctaa cccagaacgc gttatcggtg aattggcaga
     8401 gcatggtgtg atgtcaaccg cttggggtgg agattctgaa tttgttgaaa tctcagctaa
     8461 attcaaccaa aatatcgaag aattgttgga aacagtcctt cttgtagctg aaatccaaga
     8521 actcaaggca gacccaacag tgcgtgcaat cggtacggtt atcgaagcgc gcttggataa
     8581 aggaaaaggt gcggtcgcaa cccttcttgt acaacaaggt accttgaatg ttcaagaccc
     8641 aatcgttgtc ggaaatacct tcggtcgtgt ccgtgctatg accaacgacc ttggtcgtcg
     8701 tgttaaagtt gctggaccat caacaccagt ctctatcaca ggtttgaacg aagcaccgat
     8761 ggcgggtgac cactttgccg tttacgagga tgaaaaatct gcgcgtgcag caggtgaaga
     8821 gcgtgccaaa cgtgccctca tgaaacaacg tcaagctacc caacgtgtta gccttgaaaa
     8881 cctctttgat acccttaaag ctggggaact caaatctgtt aatgttatca tcaaggctga
     8941 tgtacaaggt tctgttgaag ccctttctgc ctcacttcaa aagattgacg tggaaggtgt
     9001 caaagtgact atcgtccact cagcggtcgg tgctatcaac gaatcagacg tgacccttgc
     9061 cgaagcttca aatgccttta tcgttggttt caacgtacgc cctacaccac aagctcgtca
     9121 acaagcagaa gctgacgatg tggaaatccg tcttcacagc attatctaca aggttatcga
     9181 agagatggaa gaagctatga aagggatgct tgatccagaa tttgaagaaa aagttattgg
     9241 tgaagcggtt atccgtgaaa ccttcaaggt gtctaaagtg ggaactatcg gtggatttat
     9301 ggttatcaac ggtaaggttg cccgtgactc taaagtccgt gttatccgtg atggtgtcgt
     9361 tatctatgat ggtgaactcg caagcttgaa acactataaa gacgacgtta aggaagttac
     9421 aaacggccgt gaaggtggat tgatgatcga cggctacaat gatattaaga tggatgatgt
     9481 gattgaggcg tatgtcatgg aagaaatcaa gagataagat tttttgctcc tttcttaggt
     9541 ggtgagggac gcaagcaaac cgatggtttc attgcttatt tttgagccta gggtctcaaa
     9601 aatcccctgt gatgggactg ataaatcagt tccatcactt tcaccacggc gaaagaagca
     9661 gatgacttca aattgaactt cgtttcaatt taaactgaaa atcaagaagt ttaaaatagc
     9721 taggtctgct ggcctagctt ttggttcaaa gtagagaaag gaatatcatg gcaaatcatt
     9781 tccgtacaga tcgtgtgggc atggaaatca agcgtgaagt caatgagatt ttgcaaaaga
     9841 aagtccgtga tccacgtgtc caaggtgtga ccatcacaga tgttcagatg ctgggtgact
     9901 tgtctgttgc caaggtttat tacaccattt tgagtaacct tgcttcggat aaccaaaaag
     9961 tccaaatcgg gcttgaaaaa gcaactggta ccatcaaacg tgaacttggt cgcaatttga
    10021 aattgtacaa aatcccagat ttgaccttcg tcaaagacga gtccatcgag tatggaaaca
    10081 agattgacga gatgctacgc aatctggata agaactaaag aagaggggtt gcccctcttt
    10141 tttggtggag gaaaataggt tgaatttgaa atggaaaaat attcttttat aatagattga
    10201 aactagaata gtacgcctct acttctaaaa tattgttaga aatcgatttg actgtcctga
    10261 tcgatttgtc ctgttcttgt ttcgtttcaa tataaaaaag ggattctgta ttttttaatg
    10321 ttatctaatt agaaaatgct ttttttgtag gaaatataat atgataaggt gcaaaaaaga
    10381 aataaggagt ttgtatatgg ctgaacaaga cttagctatg caagtattgc aacaagtggt
    10441 gaaactacct gttgttaagg ttgatcgttc gaaattttta gtggataagt tttccaaaga
    10501 attggatcca aaagatattc ctaccttatt ggaacaaggt acaacgactc ttctatctca
    10561 agaaatatta gatcgtgtag ctaatgcttg tattcgggac aatgtattat tagcgagtgg
    10621 gacttctgtt ttggcaggat tagctggagg gcttgctatg gcaattacca ttccagctta
    10681 tgtggctcaa ttttatggtt tctctctgaa attggcccaa gaattaggtt atatttatgg
    10741 ttatgaggat ctttgggctt cacgtgagga gttgagtgaa gatgctcaaa ataccctctt
    10801 gctttatcta ggcgtaatgt taggggtgaa tggaaccgct gctttgtttg ctacgtgctg
    10861 gtggtataac aattgccaaa caggtaatga aaacagtgcc taataaagct ttaacaaaga
    10921 cgctttggta tcctattttg aaaaaagtct taaaaatatt tggtgtgaat cttaccaagg
    10981 gagggctggc caaaggaata gggaaattta ttcctatctt gggtggtatc atttcaggtg
    11041 gtttaacctt tgcaactatg aaaccaatgg gggaaagctt gcagaaagaa ttatccaagc
    11101 tagtcaacta tagtgaagtt caatatcaag aagatgttga aacaatccga aaagaggctg
    11161 aaatcatcaa aggagaataa tatgaatcct atcaaagctt ttgctaaaat ttatggtaat
    11221 tactttttga ccgtgcaagg tgtaaaagtg atgaaaacga taaagaaaga tgaccatgtc
    11281 gttgttggtc tgggaaaact ctttattgca gataagctaa tggatacggc tcggtggctc
    11341 attaagccag aggagagaga atgaaatttt tctggacaat tcttgctatt ctttttatca
    11401 aaccgattat tgggattgtg aaattctttt ggatgatcat ttcttttgca gttcaattgc
    11461 tgttttacaa gatattggat tggttcttta aacttatcta gatggtaatc caagtcgcag
    11521 agaactagca ggaactccac tgctagtttt ttattctctt tccatatggt ataatataag
    11581 cagtaaaatc attttatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgct
    11641 gtatatatgt tactgacttc gtcagttcta tccacaacct caaagcactg ttttgagcaa
    11701 cctgcggcta gcttcctagt ttgctctttg attttcattg agtattagaa catacaatgg
    11761 aggtcgtcat ggacaatatc atcgatgtgt caattcctgt tgcagaagtg gtggacaagc
    11821 atccagaagt cttggaaatt ctagtggagt tgggttttaa accccttgcc aatcccttaa
    11881 tgcgcaatac agttggtcgt aaagtatcac ttaaacaggg ttctaagcta gcaggaactc
    11941 ctatggacaa gattgtacgc acactggaag cgaatggcta cgaagtgatt ggattagact
    12001 aatggcagat gaacggattc atgtcctacg ggatatttta ttagaattgc ataatggcgc
    12061 ctctcctgag tcggttcagg agcgttttga tgcgaccttt gcgggtgtct cggccattga
    12121 gatttccctt atggagcacg agctgatgaa ctcagactca ggtgtcacct ttgaagatgt
    12181 tatggaactc tgtgatgtcc atgccaatct ttttaaaaat gctatcaaag atgtcgaagt
    12241 ttcagatact gagcatccag gtcacccagt tcgtgtcttc aaagaagaaa atctggctct
    12301 ccgtgcggcc ttgattcgca ttcgtagatt gttagatacc tatgagttga tggaagacga
    12361 ggaaatgctt gcggagatgc gcaagggctt ggtgcgtcag atgggacttg tgggtcaatt
    12421 tgacatccat taccaacgta aggaagaact cttctttcct atcatggagc gctatggaca
    12481 cgattcacct cccaaagtta tgtggggagt ggatgatcag attagggaac tctttcaaac
    12541 agctctaacg acagccaagt cactaccaga agtgtcaatt agcagtgtaa aggaagcttt
    12601 tgaagctttt gcgacagagt ttgaaagtat gattttcaag gaagagtcca tcctgctcat
    12661 gattctcctt gagtctttta ctcaggatga ctggcttcag attgcggagg agagtgatgc
    12721 ctatggctat gccatcatcc gtccgtcaga gaaatgggtg ccagaacgac agatctttat
    12781 tgaggaaaag attgcagagg agcctgtaca gctagatacg gcagaaggtc aagttcaaca
    12841 agtcatagat acgccagaag gccattttac cattaccttt acccctaagg aaaaggaagc
    12901 tgtgctggac cgccatagtc aacaggcttt tggtaatggc tatctttcag tcgagcaggc
    12961 caatctcatc ctcaatcatc tccctatgga gattaccttt gtcaataaag aagatatttt
    13021 ccagtattac aatgacaata cgccagctga tgagatgatt ttcaaacgga cgccgtccca
    13081 agtcgggcgc aatgtcgaac tctgtcatcc gcctaagtat ttggacaagg tcaaggctat
    13141 catgaagaga cttcgtgagg ggaccaagga caagtatgaa atgtggttca agtctgagtc
    13201 gcgaggtaag tttgtccaca tcacctatgc tgcagtacac gatgaagacg gagaattcca
    13261 aggagtgttg gagtatgttc aggatatcca gccctaccgt gagattgata cggactattt
    13321 tcgtggatta gaataaggag aaaaaatgag ttacgaacaa gaatttatga aggaatttga
    13381 agcttgggtc aatacccaaa tcatgattaa cgatatggcg cacaaggaaa gtcaaaaagt
    13441 ttacgaagaa gaccaggacg agcgtgccaa agatgccatg attcgctacg agagtcgctt
    13501 ggatgcttat cagttcttgc ttggtaagtt tgaaaacttc aaagcaggca agggattcca
    13561 tgatttgcca gaaggcttgt ttggtgagcg aaattattaa acgagaaaga ttcttgattt
    13621 ttcactaaaa tcttgataga atgtttatgt taaatccttg tcagagcagg gattttttat
    13681 tgaaaggatt ttatcatgtc aaagaaactc aatcgtaaaa aacaattacg aaatggcctc
    13741 cgtcgcgcag gtgccttttc aagtactgtg actaaggttg tagatgagac aaaaaaagtc
    13801 gtgaagcgtg cagaacagtc agcaagcgca gctggtaagg ctgtttctaa aaaagttgaa
    13861 caagcagtag aagctaccaa agagcaagat caaaaagtag ctaattctgt agaagatttt
    13921 gcagcaaatt tgggtggact tccacttgat cgtgccaaga ctttctatga tgaaggaatc
    13981 aagtctgctt cagatttcaa aaactggact gaaaaagaac tccttgcctt gaaaggaatc
    14041 ggcccagcta ccatcaagaa attgaaagaa aatggcatca agttcaagta atttttcttg
    14101 agccttgcat ttccgaaaaa atcttgctac aatagagcca ttagaggtgt tttgaatccc
    14161 acattttaca gaaagtggcg gcgctgagaa gtccacaaat gtgtcaaaac tggttgctaa
    14221 tggatgaaaa attgaaataa aagtgtcttt ttgctttaaa gacgagagtt gcgggcaact
    14281 gcccgaaatt gggtggtacc gcggataaac acattcgtcc ctgtcatgta gatggcaggg
    14341 gcgatttttt gtagaaagcg aggaagaaag atgacaagag ctgagttgcc agataaaatc
    14401 gaaacagaac gtctcgtttt acgagtccgc acagtggcgg atgctgagga tatctttgat
    14461 tatgctagtc gtccagaagt ttcttaccca gcaggttttc ctccagtcaa gaccttggaa
    14521 gatgagattt attatctgga gcacattctt ccggagcgta atcaaaagga aaatctccca
    14581 gcaggctacg ggattgtcgt caaaggaacg gataagatcg ttggctctgt cgatttcaac
    14641 catcgccatg aagatgatgt gctggaaatc ggctatacct tacacccaga ctattggggg
    14701 cgaggttatg tgccagaagc tgcgcgtgcc ttgattgatc tagcttttaa agaattgaat
    14761 ctacataaaa ttgaattgtc ttgctttgga tataactttc aaagtcagcg agtcgcagag
    14821 aagcttggct tcaccctcga agctcgtatc cgagaccgca aagatgttca aggaaaccgc
    14881 tgtgacagtc tgatatatgg cttgctgagg agtgagtggg aggggatttg atgcatcttt
    14941 tcatcattgg tgctccagca tcaggcaaaa tgactattgg tcaagagtta tctcgactga
    15001 cagatgctac actattttat aaccatcaag ctattgattt tgcactagaa atctatcagg
    15061 actacacaga ggaaatgtgg gaatttgttc gtggaattac cttttctttc cttggagcaa
    15121 gtgcaagaaa tcagcgatca gtaattttaa cagacgtaat tgatttttca aatcagtacc
    15181 agctgctgta tttgaagcaa attcaggatt tgttggatga ctatcatcaa gagattcttt
    15241 ttgtggagtt ggaaacaagt cttgaagagc gcatacgtcg aaatcgaacg gagaatcgat
    15301 taaagcacaa acccttaaaa caacatattg aggtatctga aagagaaatt ttagatacag
    15361 ctgaaacact tcaattaaat tcccaacatc aaccgaatga gttgcaccac taccttaaaa
    15421 taaataatac gaatctgtct gcagaagaag ttgctaagca gattcaagat aaaatgaata
    15481 caatagagaa aggacacaca tatatctaaa caacttcatg aagacgttct caagactcaa
    15541 gaagttcaaa agtctcaatc tttttcgttc gtgattccga ccaccaaacg taactagaaa
    15601 actctacctt aatcacacct ggggtacaac cttcaaagca aatgaatcac aaagaatctg
    15661 agatttacca ttaaagcctg tatccgaggc cgtaagaata tccaatacag ttgagatagg
    15721 acctattgaa gaatgagtta gaggagaaaa tagatggcta aaaagaaaaa tagaaaaaaa
    15781 gaattaaaac gccagcaaaa gttggatatc aaagttattt ctgaagaaga ggctgcttgg
    15841 acagaaatca tggccaaaaa tccaactttt gtagaacgtc gtactattca aaatttcgat
    15901 gaactacata cagcagtgat gcaatatgct gatgaatacg gaaagtatcc agatgttcag
    15961 ctaattaatt accaactgaa aaataggact tttgattgga aacaggatca tgccatattt
    16021 agagaagcta tgcatactcc gaatacacag aagcgaaata aactgttaaa gcaagtttta
    16081 aagatcaatc cagattactt tgctgctgat tttcacttat tcttatcaga ggttgaagac
    16141 tttgatttgt caacctttaa aaaagtattg gattttgaac ttctagtttt agaaaaatgg
    16201 aaaatgaacg gctacaatag ttggaattat tttgaagctc gccctatcct gtctgctctg
    16261 atgtttctga ttgagtacta tatgatggag aacttcaatt ctaaggctat agaattgatt
    16321 gacctatatt tgagtaagcg accagaacgg tttcctccta attttgtctt ctgtatgctt
    16381 tccttgtatc atattactgg tcaggaacta aaggttgaac gtttctatcg tgaagaatta
    16441 aataaaggga aacgggatga taccattctt attcatgcca tcatctctgc tttttctcaa
    16501 ggaaaaattg aagaagcaag tcagctattt gcaaaattag tggaaatcaa tgatgaagct
    16561 gttgaattct ttatagagga agattggcaa ttcaaagtta tagatataga agaccgagaa
    16621 tgctattgtc caaattcagt tgaatcgcta caagctagtt tgtatcctct gtttgattat
    16681 ttactagaaa atattatttt aacgaaattt ttaacaaacg aatccaaaaa attccgccgt
    16741 aaaccagtat tttcgaatca ttctggtatg ataagaaatt tatccgaggt atccgattgg
    16801 cattccttta tgaatgagga aaaaatgaag ggaattcgga tggatcttgt tcacatcttt
    16861 gttgaaaatg ggattcgtac atcttcagat ttcaaaaaat ggactgaaaa agaagttctc
    16921 gctttgaaag ggattggtcc tgtaaccgtt aaaaagctga aagaaaacgg tataaagttt
    16981 aagaacgaga agtaattgtt tatggaaggg gggaggtgaa ttgtcttgaa tgaaatttct
    17041 aatttcatcc tatataccac acccaatggc catgttcagc tagatatcct tttacaagat
    17101 gaaaatcttt ggttgactca aaaaggtctt gcagagctct ttggagttga acgaagtgtc
    17161 attacaaagc acttgaaaaa catttatgat agtggtgagt tagataaggt gtcaacttgt
    17221 gcaaaatttg cacaggttca acaagaggga aatagagctg tccggcgtga acttgaatat
    17281 tacaatctgg atgctatcat ttcagttggt tatcgtgtaa attccagcaa ggctactcaa
    17341 tttagaattt gggcaaccaa gaccttgaaa gagtttatca tcaaaggttt tgttttagat
    17401 gatgaacgct tggaacaagg acagacagtt tttggacaag attatttccg tgagctttta
    17461 gaacggattc gctctattcg ttctagcgag cgccgaatct atcaacaaat tacggatatc
    17521 tttgctgaat gtgccataga ttatgatcaa aactcagata ttactaaaaa tttctatgct
    17581 atggtgcaaa ataaatttca ttatgcaatt actggaagta ctgctgcaga aattatctat
    17641 caacaagccg atgctagtag agaaaaaatg ggattaactt cttggaagaa tgcacctgat
    17701 ggacgagtgc tcaagtcaga tgtaacggta gccaaaaatt atttgcaaga aaaagaaatt
    17761 cgacaactag agcgaactgt tacagcctat tttgattata tcgagggttt ggttgagcgc
    17821 cgtaatactt ttacaatgcg aggattggca gatagtattg atcgctttct atcttttaat
    17881 gagtacgaaa ttttagaagg aaaaggaagt atttccaaga aacaagcaga ctcaaaagcc
    17941 atccaggagt atgaaaaatt taaccgaact caaaaaattc tatcggactt tgataaacat
    18001 attctgaaga taatgagaga aagttaatgt aaaattttca ccatttcttt gcttatagaa
    18061 gatactgaaa aaatcagatg tgctgaatca aggcctatct tctacatact aattttattt
    18121 aaagatatta actagaaagg acaaacacat gtctaaagaa ctttcaccta aatacaatcc
    18181 agccgaggtt gaggctggtc gttaccaaaa atggcttgac gctgatgttt tcaagccttc
    18241 aggagatcaa aaggctaagc cttattcgat cgtgattcca ccaccaaacg ttactgggaa
    18301 acttcacctt ggtcacgctt gggatacgac tttgcaagat atcatcatcc gtcaaaaacg
    18361 tatgcaaggt tttgacacgc tttggcttcc aggtatggac cacgcgggga ttgcgactca
    18421 ggctaaggtt gaggagcgct tgcgtggaga gggcattaca cgttatgacc tcggtcgtga
    18481 gaaattcctc gataaagttt gggaatggaa agatgagtat gccactacca tcaaagaaca
    18541 atggggcaag atggggctct ctgtagacta ctctcgcgag cgtttcaccc ttgacgaagg
    18601 tttgtcaaaa gccgttcgca aggtctttgt ggacctttac aagaaaggct ggatctaccg
    18661 tggtgagttt atcatcaact gggacccagc agctcgcaca gccctttctg atatcgaggt
    18721 tatccacaag gacgttgaag gtgccttcta ccacatgaac tacatgctag aagacggctc
    18781 acgcgccctt gaagtggcga caactcgtcc tgagaccatg tttggggatg tggcggttgc
    18841 ggttaatcca gaagacccac gctacaagga cttgattgga aaaaacgtca tccttccaat
    18901 cgctaataaa ttgatcccga tcgttggaga tgagcacgcc gaccctgagt ttggtactgg
    18961 tgtcgtaaaa atcacccctg cccacgatcc aaatgacttc ttggttggtc aacgtcacaa
    19021 cttgccacaa gtcaacgtca tgaacgatga cggaactatg aatgacttgg ctttcgaatt
    19081 tgcaggcatg gaccgttttg aagctcgtaa ggcagtcgtt gccaagttgg aagaaatcgg
    19141 tgctcttgtc aaaatcgaaa aacttgttca cagtgttggc cactcagaac gtacaggtgt
    19201 cgtggttgag ccacgcttgt ctactcaatg gttcgtcaag atggaccaat tggccaaaaa
    19261 tgctattgcc aaccaagaca cagatgacaa ggtagaattc tacccacctc gtttcaacga
    19321 taccttcctt caatggatgg aaaatgttca cgactgggta atctctcgtc agctctggtg
    19381 gggtcaccaa atccctgctt ggtacaatgc tgagggtgaa atatatgtcg gcgaagaagc
    19441 tccagaaggt gaaggttgga ctcaggacga agatgtcttg gatacgtggt tcagttcggc
    19501 cctttggcca ttctctacca tgggctggcc ggatgtcgac tcagaagact tcaaacgtta
    19561 ttatccaaca tcaactttgg tgactggtta tgatattatc ccgttctggg tatctcgaat
    19621 gattttccaa ggtttggaat ttactggcaa atcgccattc aaaaatgcat tgattcatgg
    19681 tctgattcgt gacgaggaag gccgtaagat gtctaaatca ctgggcaatg ggattgatcc
    19741 gatggatgtt attgataagt acggaacaga tagcctgcgt tggttccttt caaacggttc
    19801 tgcaccaggt caagacgtgc gcttctctta tgagaaaatg gatgcttcat ggaacttcat
    19861 taacaagatt tggaacatct ctcgctacat cctcatgaac aatgaaggtt tgacccttga
    19921 gcaagcaact gccaatgtgg aaaaagttgt taacaaggaa gctggaaatg tcacagaccg
    19981 ctggattctc cacaacctca atgaaaccat cggaaaagct actgctaact ttgacaagtt
    20041 tgaatttggt gtggctggcc acatcctcta caactttatc tgggatgaat ttgcggactg
    20101 gtacgttgaa ttgactaagg aagtccttta tagcgacaac gaagaagaga aagtcatcac
    20161 acgctctgtt ctcctttaca ctctggacaa gatccttcgt ctccttcacc caatcatgcc
    20221 attcgtgaca gaggaaatct ttggacaaat ctcagaaggt tctatcgtga cagcagaata
    20281 cccaactgtc aacccagcct ttgaagacct tgcggctcac actggtgtcg aaagtctcaa
    20341 agacttgatc cgtgccgttc gtaatgcgcg tgcggaagta aacgtagcac caagcaaacc
    20401 tatcaccatc cttgttaaga caagcgatag cgacttggaa gccttcttta acagcaatgt
    20461 caactacatc aaacgcttca caaatccaga acacttggaa attgcatcaa atatccctgc
    20521 acctgaactc gctatgtcaa gtgtcatcac aggagcagaa atctacttgc cactcgctga
    20581 cctcctcaat gtcgaagaag agctggctcg tctcgacaag gaactggcta aatggcaaaa
    20641 agaactggac atggtcggta agaagctctc taacgaacgc ttcgtagcca atgccaaacc
    20701 agaagtcgtc caaaaagaac gcgacaaaca agccgactac caagctaaat acgacgcgac
    20761 agtcgcacgt attgatgaga tgaagaaact agtgaaataa acatagaaac ctcggcaatt
    20821 tgctggggtt tttggtataa taaatcttga tggatgaaaa atatgagaag tgaaacaaga
    20881 tttttaaaaa acaatggaat ttattataca aataataagc ttgcaaatat catgatcgat
    20941 aatctagaga ttgattttga tggtaatttt acattactag agcttgctgt cggtgaagga
    21001 catatattat gtcttatttt gagaaggtta
//
LOCUS       DAVLZS010000035        20544 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLZS010000035 DAVLZS010000000
VERSION     DAVLZS010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.035"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            16..1791
                     /locus_tag="VYO88_001407"
     CDS             16..1791
                     /locus_tag="VYO88_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HEV1719492.1"
                     /translation="MANNRKTETLGVSYLSTFIDKHELLQSYFESNDKTPVWDGEIHV
                     LKSPSEKKDEILGKVPVQIKTTRQKKDVLKSFSLDTRDLELYKPNGGVVLFVVWLNED
                     NGLRDIYYKSLPPLSIKNLLKKSKLKNKSTNRKKLSIEIFKLDEKKMYPMLVDFINNS
                     QKQYSFINVEGISVEDIPDDKTLKFYFYGQEKEEIFNYQEEHDLFIYYLDPITGIEIP
                     LENTIKIVETEEETDLIIKIGDYVFQDVKRHRFPDGSVQLHFGESFTMSFDIKKKQFK
                     FNYTRPDLLSKAIKCTQVFQELGKIGYFTLNGNKIELDERSIKDISSLDLEADIKGLL
                     KISNFMKKMGIQKDVDLSCFDKQSQRNLNILYSGLVLKKKVALNYNESKLLHLNIANI
                     HIITLYSFLSDKNGTMIDIFTETPWCREGETEDEDYLDISIFEVFEPNDWLKIDNCKI
                     DSVIASYQRLVDNKLKYEGADRTILKIVIAADMAEDKTKRELLLNWAQCLSDWNLKYS
                     KNCEMAIINDLQIKSRVRKLNSKETETLTNILVNSNDNYELCFGSSVLLKSKPQADLF
                     WNKLDNETKERYKDFPIYTLYMKLS"
     gene            complement(2002..2808)
                     /gene="yidA"
                     /locus_tag="VYO88_001408"
     CDS             complement(2002..2808)
                     /gene="yidA"
                     /locus_tag="VYO88_001408"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1719493.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTLVL"
     gene            complement(2821..4125)
                     /locus_tag="VYO88_001409"
     CDS             complement(2821..4125)
                     /locus_tag="VYO88_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1719494.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            4197..4574
                     /locus_tag="VYO88_001410"
     CDS             4197..4574
                     /locus_tag="VYO88_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1719495.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            4665..4997
                     /locus_tag="VYO88_001411"
     CDS             4665..4997
                     /locus_tag="VYO88_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1719496.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            5009..6580
                     /gene="ffh"
                     /locus_tag="VYO88_001412"
     CDS             5009..6580
                     /gene="ffh"
                     /locus_tag="VYO88_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1719497.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(6775..8058)
                     /locus_tag="VYO88_001413"
     CDS             complement(6775..8058)
                     /locus_tag="VYO88_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV1719498.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(8361..9074)
                     /gene="rsmG"
                     /locus_tag="VYO88_001414"
     CDS             complement(8361..9074)
                     /gene="rsmG"
                     /locus_tag="VYO88_001414"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1719499.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            9168..9728
                     /locus_tag="VYO88_001415"
     CDS             9168..9728
                     /locus_tag="VYO88_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1719500.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTSEEEKSVPKVDFSGLGD"
     gene            9730..10629
                     /gene="htpX"
                     /locus_tag="VYO88_001416"
     CDS             9730..10629
                     /gene="htpX"
                     /locus_tag="VYO88_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1719501.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIILLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10778..12337)
                     /locus_tag="VYO88_001417"
     CDS             complement(10778..12337)
                     /locus_tag="VYO88_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1719502.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLSKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQFLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(12576..12893)
                     /locus_tag="VYO88_001418"
     CDS             complement(12576..12893)
                     /locus_tag="VYO88_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1719503.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSPLIGLGSLKLNNQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            13063..13605
                     /locus_tag="VYO88_001419"
     CDS             13063..13605
                     /locus_tag="VYO88_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1719504.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFASLQGLFDGDE"
     gene            13605..14234
                     /gene="nth"
                     /locus_tag="VYO88_001420"
     CDS             13605..14234
                     /gene="nth"
                     /locus_tag="VYO88_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1719505.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNPFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            14445..14966
                     /gene="pyrR"
                     /locus_tag="VYO88_001421"
     CDS             14445..14966
                     /gene="pyrR"
                     /locus_tag="VYO88_001421"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1719506.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            14985..15908
                     /locus_tag="VYO88_001422"
     CDS             14985..15908
                     /locus_tag="VYO88_001422"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1719507.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            15958..17037
                     /gene="carA"
                     /locus_tag="VYO88_001423"
     CDS             15958..17037
                     /gene="carA"
                     /locus_tag="VYO88_001423"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1719508.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            17350..20526
                     /gene="carB"
                     /locus_tag="VYO88_001424"
     CDS             17350..20526
                     /gene="carB"
                     /locus_tag="VYO88_001424"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1719509.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         6150 a         3846 c         4512 g         6036 t
ORIGIN      
        1 tttagaggtg cagatttggc caataatagg aaaactgaga cattaggtgt ttcatatctt
       61 tcaacattta tagataagca tgagttactt caatcttatt ttgaaagtaa tgataaaact
      121 ccagtatggg atggagaaat tcatgttctt aaatcaccga gtgagaagaa agacgaaata
      181 ttaggtaaag tacctgttca gattaaaact actagacaga aaaaagatgt gttaaaatcc
      241 ttctcattag atactagaga tttagaacta tataaaccaa atggtggagt agttttattt
      301 gtagtttggt tgaatgagga taatggttta agagatattt actataagtc attacctcct
      361 ctttctataa agaatttgct caaaaagagt aaactaaaaa ataaatctac aaataggaag
      421 aaactttcca tagagatttt taaactggat gagaaaaaaa tgtatccaat gttagtggat
      481 ttcataaaca atagtcagaa gcagtatagt ttcataaatg tcgaaggtat ttcagttgag
      541 gacattcctg atgataaaac tctaaagttc tacttctatg gtcaggaaaa agaagaaatt
      601 tttaactatc aggaagaaca tgatctcttt atttattatt tagatcctat aactggcata
      661 gaaatacctc ttgaaaacac aataaagatt gtagaaactg aagaagaaac ggatttaatt
      721 ataaaaatag gcgattatgt ttttcaagac gtaaaaagac atcgttttcc tgatgggagt
      781 gtacagcttc attttggtga aagctttaca atgtcttttg acataaagaa gaaacaattc
      841 aaatttaact atactaggcc ggatttgctg tcaaaagcta taaagtgtac tcaggtattt
      901 caagagctag gaaaaatcgg atattttacc cttaatggta ataaaataga gttagatgaa
      961 cggtcaataa aggatatttc ttcacttgat ttagaggctg atataaaggg attgttaaaa
     1021 atttctaact ttatgaaaaa aatgggtata caaaaagatg ttgatttatc ttgctttgat
     1081 aaacaatctc aaagaaatct aaatattctt tattcaggtc ttgtcttaaa aaagaaagtt
     1141 gctttaaatt ataatgaatc gaaattactt cacctaaata ttgctaacat ccacattata
     1201 actttatata gttttttgtc agataaaaat ggaactatga tagacatttt tactgaaact
     1261 ccttggtgcc gggaaggaga aactgaagat gaagattatt tagacatttc aatttttgaa
     1321 gtatttgaac caaacgattg gctaaaaatt gataattgta aaattgattc agttattgcc
     1381 tcgtatcaaa gattggtaga taataagctg aaatatgaag gcgctgaccg tactatttta
     1441 aaaatagtta tcgctgcaga catggcagaa gataagacta aaagagagtt gttacttaat
     1501 tgggcgcaat gtctttctga ctggaactta aaatactcaa aaaattgtga gatggctata
     1561 ataaatgacc ttcaaataaa atctagagtt cgtaaattaa acagcaaaga aacagagaca
     1621 ctaactaata ttttagtaaa tagtaatgat aactatgaac tttgtttcgg ttcatcagtg
     1681 ctattaaaat cgaaaccaca agctgatttg ttttggaata aactggataa tgagacaaaa
     1741 gaaagatata aggactttcc tatttatact ttgtatatga aattatcgta aaattaaaag
     1801 agattataaa gagataacat atagaaatag agagtgattt attacaattc agtaccacaa
     1861 attaagaaag caatgcctat tttttgtact ctcaagattt aagtaactgt acaactgcaa
     1921 ttaaatttat taatttactc tcattgtgat atattcatac aaaaaccgct cagctgagcg
     1981 gttttagtct attctttcct tttacagtac caatgtacga atagcatggg caacgccgga
     2041 ttcgtcattt gttttggtga tgtatttggc gatttttttg atttctggat ttccgttttc
     2101 catgactaca gggttgccaa cgacttccag catggcacgg tcattttctt cgtctccgat
     2161 agccatggtt tcatctttgg ttaatcctag tttttcagct aagtgagtaa tagctgaacc
     2221 cttgtctaca ttctttttaa ggagttcgag gtagaaagga gcagatttgt tgatagagta
     2281 gcgctcgtaa aattctgctg gaattttttc aatcgcagca tcgagaattt ctggttcatc
     2341 gataaacata catttaacaa tttctttgcc agccatttct tcaggggtac ggtagaagat
     2401 aggcatgctg acgagggttg attcgtgtac agtgtatttt ccgatattgc gatttgcagt
     2461 atagataccg tccttggtaa tggcatgcat gtggacaccg agcttgcgac tgaggaattc
     2521 catatctaga taatcctcat aagtcaagga ttcgctgata atctcatgtc ctgtagcagt
     2581 ttcttggaca agggcaccgt tgaaggttac cacatagtcc ccctcgtctc tcaactgcaa
     2641 gtcgtctaga agtttggcaa cgcctgcgat agggcggcca gttgcaatca cgactttgac
     2701 accagcttct ttggcatctt ggatggcaga aaaaacttca ggagtgattt ccttttggct
     2761 gttgacaagg gttccgtcga tatcaacggc aattagttta atactcatac atttcctctt
     2821 ctagttttta tttggggtaa aatgatcgtt ctcaatcaag tgtaaaaatt gctgggtaat
     2881 gcttgcaaag atgctgtttt ggtccaacat ttcttttgga aaataaaagc gattatctcc
     2941 gtggcgactg ccagcaaggg attggacgat aggagacagg ctagagagtt cggccagttc
     3001 tccatttttt tgtaaaatct caatctgtgt ccgtgggttt tcagattcgg gacgatagat
     3061 atcataaggg aggtcaaagt tcttatgaat ggcagtgtag tagtcgggat caaagccgat
     3121 atcctcaacc aattttctca tgctagtaag ttgatcttgg tcctcttgtg aaaaggtaat
     3181 ggatttaaag accttgcggt tgacaaagcg atgcgataaa tctgcaagaa tcttgtcagg
     3241 actggtcatc caaagctgga agtaggtatt catcacgcca tcatccagag ccagatagtc
     3301 agtcaaggtc acattttttt cgaagaaagg caggaggtgt ggagaagttc gggcaaagaa
     3361 atccttgtcc tcaggataga gttccttggc gcgtttgaga agattctgta ggagaacttc
     3421 catggcgcgt gttgcggggt ggaaataaac ctgcatgtac atctggtagc gactgaggac
     3481 gtagtcttcg atggcgtgca tgccattgcg ctgaaaggcg ataccatttt cgataggacg
     3541 aatgactcgg aggattcgag tcaggtcaaa ttccccatag gatgctcctg taaaatagga
     3601 gtcgcgcaag agatagtcca tgcgatctgc gtcaatctga ctagaaatga gctgcacgac
     3661 ctgcttatta ggataggtat ggtcaatgac actggccacc ttttctggga aatcaggtgc
     3721 cacttgtagc aggacttggt gaatctctgt ctcaggattt tgaataatct cctgagtaat
     3781 ggcttcatgg tctgtatcaa agagatgttc aaaagtatgg gagtaggcac catgcccaag
     3841 gtcgtgtagg agagcagcgg tcatggtcaa gagagactcg gcaggattcc attcctcagg
     3901 atatttttct tcgaaaatct ctgtgatgcg tcgtgcaatt tcatagactc ctagacagtg
     3961 agagaagcga ctgtgttctc caccgtggaa ggtataactg gaagttccca gttgtttgat
     4021 ccggcgcaaa cgctgaaatt cttttgtatt aatcaagtca tagatgattt gattattgac
     4081 atggatgtag ttgtgaactg ggtcacggaa tactttttcg ttcatatgac cattatagca
     4141 aaatcctgct ctttttggta aaatagtagg acaagagaca agaaagaggg cctgatgtga
     4201 agattcggat gcgaaataca attcagtttg atgagcagtt ggaagtgatt gaccagcttt
     4261 atgatgtgga agtgcatgaa aaaggagatt atagctacct gcttttctat aatgaggaaa
     4321 aggaaaaagt agtgattaaa tttcatggtc aagaacttat gatgagccga ttttctaatc
     4381 ccaagaccat tatgcgcttt ctaaaggata gcgatagttt agcctatatt cctacaccta
     4441 tgggcatgca ggagtttatc atccaaacga gccattatca agttgatagg caaaagattg
     4501 aactagatta tcaactacaa aatcaagagg gacatccttt tgccagctat caattggaaa
     4561 ttacttgggg ctaggctcat gtctttttca aatttagcta tctatcttct tggatcggct
     4621 tcctagtgtg gtagattagg ctaatttttg gtataataaa agttatggaa atcgaaaaaa
     4681 ccaatcgtat gaatgcgctc tttgaatttt atgcggcgct tttgacagat aagcaaatga
     4741 attatatcga gctctactac gctgatgatt acagccttgc tgaaattgcc gaggagttcg
     4801 gtgtcagtcg tcaggctgtc tatgacaata tcaagcgaac agaaaagatt ctggaagatt
     4861 atgagatgaa attgcacatg tactcggatt atattgtccg cagtcagatt tttgatcaga
     4921 ttttggagcg ctatcccaag gataactttc tgcaggagca gatagaaatt ttaacaagca
     4981 ttgataatag agaataagag gaagaaaaat ggcatttgaa agtttaacag aacgtttgca
     5041 gaacgtcttt aaaagtctac gtaaaaaagg aaaaatctct gaatctgatg tccaagaggc
     5101 aaccaaagaa attcgcttgg ccttgctcga ggccgacgtt gccttgcctg ttgtaaagga
     5161 ctttatcaag aaagttcgtg agcgtgcagt cgggcatgag gtcattgata cacttaatcc
     5221 tgcgcaacag attattaaaa tcgttgatga ggaactgaca gctgttttag gttctgatac
     5281 ggcagaaatt atcaagtcac ctaagattcc tacaatcatc atgatggttg gtttgcaggg
     5341 agctggtaaa acaacttttg caggtaagct ggctaacaaa ctcaagaagg aagaaaatgc
     5401 ccgtcctttg atgattgcgg cggatattta tcgtccagct gccattgacc agcttaagac
     5461 cttgggacaa cagattgatg tgcctgtctt tgcacttgga acagaagtac cagctgttga
     5521 gattgtacgt caaggtttgg agcaagccca aactaatcat aacgactatg tcttgattga
     5581 tactgcgggt cgtttgcaga ttgatgagct cctcatgaat gagcttcgtg atgtgaaagc
     5641 attggctcaa ccaaatgaaa tcttgcttgt cgttgatgct atgattggtc aggaagcagc
     5701 caatgttgcg cgtgagttta atgctcagtt ggaagtgact ggggtcatcc ttaccaagat
     5761 tgatggcgat actcgtggtg gtgctgctct gtctgttcgt cacattactg gaaaaccaat
     5821 caagttcact ggtacaggtg aaaagattac ggacattgaa accttccacc cagaccgcat
     5881 gtctagccgt atccttggta tgggggatat gctcactttg attgagaaag cttctcagga
     5941 atacgatgaa caaaaagccc ttgaaatggc tgagaagatg cgcgaaaaca cctttgattt
     6001 taatgatttc atcgatcaat tagatcaggt gcaaaatatg gggccgatgg aagacttgct
     6061 caagatgatt ccaggtatgg ccaacaatcc agcccttcaa aacatgaagg tggatgaacg
     6121 ccagattgct cgtaaacgtg ccattgtgtc ttcgatgaca cctgaagagc gtgaaaaccc
     6181 agatttgtta aatccaagcc gtcgccgtcg tattgctgct ggttctggaa atacattcgt
     6241 cgaagtcaat aaattcatca aggactttaa ccaggctaaa cagctcatgc agggtgttat
     6301 gtctggggat atgaataaaa tgatgaagca aatggggatt aatccaaata accttcctaa
     6361 aaatatgcca aatatgggag gaatggatat gtctgccctt gaaggaatga tgggacaagg
     6421 cggtatgcct gacttatcag ctctcggagg agcaggaatg ccagatatga gccagatgtt
     6481 tggtggcggt ttgaaaggta aaattggtga atttgccatg aaacagtcca tgaaacgtat
     6541 ggctaacaaa atgaagaaag cgaagaagaa acgcaagtaa gacaagagat tgatgcaaat
     6601 ctcatttgat gagaaaataa agtaaaaatt tctatgataa aacgtacagt atcaaggttt
     6661 tagaatatct gatattatac gttttttgat tttaataatt ttgttaagac acttttatta
     6721 tggtatgcga aaaatccact cagctgtctg agtggattag gtgtatttag actcttagtc
     6781 tttattttcg tatggcaaga tcaagttcaa gatgattcct gtcatggctg aaagggcagt
     6841 acctgaaagt gtaactggac caagtttaag gatagctcct ccaagtccaa gaaccaacat
     6901 agcacttgcg atgatgaggt ttcgcatttg agcgaaatca acacgttctt taatcaagac
     6961 tttcaaacca ttgctggcga taaccccata gagaaggatt gacataccac caagtacagc
     7021 gtttggaata gttgaaatca aggcagtgaa tttaccaagg aagctgaggg caatcgcgat
     7081 gaaggcagcg ttacggataa ctgagacaga agcgatacga gtcataccga taacccctgt
     7141 attttctccg taagttgtat tggctggtcc accaaggaag gcagaaacag aagttgcgat
     7201 accgtcacca ataagagtac ggtgaagacc tggttctttt aagaattgac ggccacagat
     7261 ttgacccaaa acagtatggt ctccgatatg ttcagaaatt gttacgatag cgattggcaa
     7321 gatagcgatg gcttctggac caaagtaaag attgtactct ttaaaggcac cacctgtgct
     7381 aaatggcaag tagaaaccag gaatttcaaa ccagttagct tctaggacag gcgtaaagtc
     7441 aaccaaacca agagttagtg cgaagaggta accaccgata atggcaaaga ggaatggaat
     7501 gattcgtagg aagccttttc cttttgtatt gataaaggca gcaattagga aagtaacaac
     7561 ggctaccaga gcatttttcc aatttccgtc tgctacaaga cctgcattgg taacagctga
     7621 acctgcaagt ccaagaccga taacgatgat cataggaccg ataatgattg gtggcaagag
     7681 tttatcaatc cattttgttc ctacaaatcg gatgctggta gcaacaagga catagaccaa
     7741 accagtcaag ataacccctg tttgagcagc agatacatcc ccccccattt ctttcatagc
     7801 cagtgacata gctgtgataa aggcgaatga agaacctaga taaactggaa ctttaaaacc
     7861 agtagcaatc atgtagatga gtgttccaac acctgaagca aaaagggcaa cagatacagg
     7921 cattcccaaa atcaatggta ccaagatggt cgcaccaaac atggcgaaaa cgtgttggaa
     7981 gctaaggaga attccttttc catccgaagg acgttggtca acgtctagta acaaatcaac
     8041 agttgattct tgtttcatat aaacctcact tttgggcatc agaaaagagc ccattatttt
     8101 acagcaatag gccctcagag taagacttct ctaaaatcta gactttaaag agtttcaaat
     8161 atttttgcgt cttcgtcacc tcacgggatg acattaaaaa cctttgctta ggatagtata
     8221 gcagaaaaaa atgattttgt aaatcatttt ttcccgagcc tagaaataaa agagcgaggc
     8281 tgattttgta aatcattttt tcccgagcct agaaataaaa gagcgaggct gattttgtaa
     8341 acatttgttt actaaaaaat ttaaagtggg cgtttatttg gcataccagc cttacgtgga
     8401 tatttatttg gtgtttcttt tttcttttct accactgtga tatagcgcgg atctctattc
     8461 ggtagggcgt agctgagatt gtcttcgacc ttactaaaaa ggagattgag ggcattctta
     8521 gcttctaata attcctcagg cgcattgctg gccttgagtg ccaatagttt gccaccaacc
     8581 ttaaggtagg gaatagtcaa ttcagatagg acctgcatac gggcaaccgc acgagctgtt
     8641 acaaaatcat attgagcacg gaagttcttg tcttgggcaa aatcttcggc acgtccgtgg
     8701 tagaaatgaa ctccgttcaa atccagttct tgagccaaga gttgtaggaa gttgatgcgc
     8761 ttattgagtg aatcaataat ggtcacatct aactccggat agagaatttt cattggtaga
     8821 ctaggaaatc ctgccccagc cccgatatca agaagtttga tagtttcatt gggaatcaaa
     8881 ccttgaagaa tgggtgcaat cgaatcgtaa aaatgtttga gataaacttc ttccttgtcc
     8941 gtaatcgccg tcaaattaat cttctcattc cactcgacca agagctcaaa ataacgttca
     9001 aattgttctt tttgctggtt cgaaagtgga agattctgct cggcaagcaa gttgtaaaat
     9061 gtttctggtt tcatagttat ttccttcttt agtatcatct tattttacca caatcattaa
     9121 aaatttgata tactggtact aatctaaaag cagaaaggac ttatattatg acttggatta
     9181 ttcttggagt tatcgctctt attgttattt ttgtgattgt tagctataac ggtttggtta
     9241 aaaatcgtat gcaaaccaag gaggcttgga gtcagattga tgttcagttg aaacgtcgaa
     9301 atgacctctt gccaaacttg attgagactg taaaaggtta tgccaaatat gaaggttcta
     9361 cccttgaaaa ggtggcagaa ctacgtaacc aagtggcggc agcgacttca ccagcagaag
     9421 ctatgaaagc cagtgatgcc ctcactcgtc aggtttcagg tatttttgca gttgcagaaa
     9481 gctatccaga tttgaaagct agtgctaact ttgttaaatt gcaagaggag ttgacaaaca
     9541 cagaaaataa aatttcttac tctcgtcaac tctataacag tgttgtcagc aactacaatg
     9601 taaaattaga aactttcccg agcaatatta tcgctggaat gtttggattt aaagcggcag
     9661 atttccttca aacatctgaa gaggaaaagt cggttcctaa agttgatttt agcggtttag
     9721 gtgactaaga tgttgtttga tcaaattgca agcaataaac gaaaaacctg gattttgttg
     9781 ctggtatttt tcctactctt agctcttgtt ggttatgcgg ttggttatct ctttataaga
     9841 tctggacttg gtggtttggt tatcgcactg attatcggct ttatctacgc tttgtctatg
     9901 atttttcaat cgacagagat tgtcatgtcc atgaatggag cgcgtgaggt ggatgagcaa
     9961 acggcaccag acctctacca tgtagtggaa gatatggctc tggtcgctca gattcctatg
    10021 ccccgtgttt tcatcattga tgatccagcc ttaaatgcct ttgcgacagg ttctaatcct
    10081 caaaatgcgg ctgttgctgc gacttcaggt ctactagcta tcatgaatcg tgaagaacta
    10141 gaagctgtta tgggacatga agtcagtcat attcgtaatt atgatatccg tatttcgact
    10201 attgcagttg cccttgctag tgctatcacc atgctttcta gtatggcagg tcgtatgatg
    10261 tggtggggtg gagcaggtcg cagacgaagt gatgatgacc gagatggaaa tggtcttgaa
    10321 atcattttgc tagtggtttc cctactagct attgtactgg cacctctcgc tgcaaccttg
    10381 gttcagctcg ctatttctcg tcagagggaa tttctggcag atgcatctag tgtcgagctg
    10441 actcgcaatc cccagggaat gattaatgcc ctagataagt tggacaatag caaacctatg
    10501 agtcgccacg tcgatgatgc tagcagtgcc ctttatatca atgatcccaa gaaaggtggg
    10561 gggttccaaa aactctttta tacccaccca cctatctcag aacggattga acgtttaaaa
    10621 cagatgtaaa atgaaggctg gaaaaaagtc tttaaaatct gaaaaacgca taatatcagg
    10681 tgtgaaaact tgatattatg cgttttacta tgggaagatt tacttctttt tctcctaaaa
    10741 ttgtgttttt gccccaccta tctgctatgt tgcaaattta taaatcttct aaattaacta
    10801 gcttcaaacc gtgttctgtc atgcgataga tgatcgagca gacttctttt aagaaacgac
    10861 ggtcatgcga aacagtgatg agaccgcctg gataggttgc aaagagtttt ctgatttggg
    10921 gttgagaagt gggagaaaag tttcgtgtgg gttcatccag caggagaaag tttggtttgc
    10981 gcaggactaa atccaaaagc aggagttttc cctgttgtcc gccagataag gagcgaattt
    11041 gatgctgcat ttctggataa ctgaaattga gactggctag gtgagattgg attttctgta
    11101 gttcctcttt ttccccagtt ttgctgaggt aggctattgg tgataaatcc aattgcagtt
    11161 ttttgtggta atcttgtggc ataaaaccaa gggaaatctc tcttttatca ttcagaaatt
    11221 gctttaattt ggctaacaga gttgatttcc caacaccatt tggcccgata ataccgattt
    11281 tttcttgccc acggacagtt agttgtagtt tttgaaccaa aactcggtcg tcaatggaca
    11341 aattttcttt ttccagttgg actaagactt tagaagctgg taatggttgg atgtctgaaa
    11401 agaaaagttg gatttgttcc tcttcaagtg gtttttgagt catggactga gctgcctttt
    11461 cgtagcgttt ttcttgtgag aggacagttt tcatcttttt agacaatagg cgaccggcag
    11521 tactatcttt ggtagctcga agcgcagttt ctacattttg cttaactctc cgatgttttt
    11581 ccatggtttt atcgtaggct ctttggttat tagcagcttg ctgactttgt ttggcaaaat
    11641 tagcctttct ctgctcacta tagctatcat agtctaaatg ctctactagc gtttccgctt
    11701 ctttacggtg tttgaccagt cgcaagtgaa caatagtgtc tgccgtttca gaaagaaagt
    11761 cttcatcatg ggaaatgaaa ataacggttt gcctggtctt ttgaatctgg ccttttagcc
    11821 aatcaactgt ctcaaggtct aggtcatttg aaggttcatc taaaaataga atctcaaagg
    11881 gtttggctaa ctcatggata agctgaattt tcaaagcttc tccccctgat agattgccaa
    11941 tctcttggtc acttgcgaaa cgattgctat caaaatgcaa ttcctccgcc aaacgataga
    12001 ggatactgta gtctaaatca atagaatcta aaaagaagta gtcgtgtaaa gttttctttt
    12061 tcagctcctc gggaagtttt tgaggaatgt aggccagtga ctgatagtca gattggatgt
    12121 ttcccttgat agtgaaatca gacaaagctt cccccattaa aattttaagt aaggttgatt
    12181 tgccatttcc ttcttcacca ataatagcaa ccttttcccc gtcttggatg gtcatggtta
    12241 ggtcagagac aaggtctcgt aaatctttgt tttgtgtgat ggtcaggtga ttgattttta
    12301 tcatatgatt tccctttcta gaatgttcat agtgcataac aaaaagctct actttaccta
    12361 gtagagccca aagtctatgt caaaaaaact ctattaacat gccagaaaaa gagcataaaa
    12421 gagcacacaa aaagagacaa aaacaagatc tactaaataa aggttcttta tttgatagac
    12481 ttagttgttc atgtctccct tacctccgag tattagtatc tttatactat acctttaagg
    12541 aaattttgtc aacagaaaac tggaaattct atgctctaaa atccaaaaac aggtccatag
    12601 agacttagta cgtgtttgac atgctcgtaa tggattttat catagtttcg ccaagcagtg
    12661 cgtgcttgat tgtttagttt taggctaccc agtccaatca gaggactggt gggttggtaa
    12721 aatttctcaa gatcaattaa gatactgttg ttcaactgtt ccgttttttt gagctcttgc
    12781 atagtagtgt ttagcagctc ttgtagtcga atatcatctg ccgtaccctg tttacagttt
    12841 tggtagcttt tatttaactt ggataggagt tgaatgagtt tcttgtcttc catgtgagca
    12901 tcctccttga tctgatgtac tctttcccta tagtatagca ctaaaaaaca aaactataat
    12961 agtaaatatg ttaaaatttt gaattttaat tacaaagttt ggtgtgctga tttgtagcct
    13021 tttcatggta taatcaagag agtaaatctt tatggaggaa gtatgaaatt aaatattcaa
    13081 gaaattcgta agcagtctga aggtttgaac tttgaacaaa cgttagattt agttgatgac
    13141 ctgcgtgcac gtaatcaaga aattttagat gtaaaagata tccttgcagt tgggaaagta
    13201 caatatgaag accgtatgta tttcttagat tatcaactat cttataccat tgttcttgct
    13261 tcgagtcgca gtatggagcc agttgagtta gttgaatctt atccagtcac ggaagttttc
    13321 atggaaggcg caactaacca tctaaatcaa gaaattttag atgatgactt ggtcttgccc
    13381 atcgaaaatg gggcgcttga ccttgctgag agtgtatcag acaatatcct gctaaacatt
    13441 cctatcaagg tcttgacggc tgaagaagaa gctggtcaag gatttgtctc aggaaatgac
    13501 tggcaaatca tgacagagga agaataccaa gctcaacaag cagtaaagaa agaagaaaac
    13561 agtccttttg ctagcttaca aggactattt gacggagatg aataatggtc ttgtcaaaaa
    13621 aacgagcacg aaaggtgcta gaagaaatca ttgccctctt cccagatgcc aagcctagtc
    13681 ttgattttac caatcctttt gaactcctgg ttgcggtcat gttatcagcc cagacgacag
    13741 atgcagcggt aaataaggcc acaccaggtc tctttgttgc ctttccaaca ccccaagcta
    13801 tgtctgtagc gacagagagt gagattgctt cacatatttc tcgcttggga ttgtatcgga
    13861 ataaagctaa attccttaaa aaatgtgccc aacagttact agacgatttt gatggtcaag
    13921 tccctcagac acgtgaagaa ttggagagtt tggcaggtgt tggtcgcaag acagccaatg
    13981 ttgtcatgag tgtaggattt gggattccag cctttgcagt ggatactcat gtggagcgta
    14041 tttgcaaaca ccacgatatt gtcaaaaaat cagcgacgcc acttgaggtg gaaaagcggg
    14101 tcatggatat cttgccgcct gagcagtggt tagctgccca tcaggccatg atttattttg
    14161 gaagagccat ttgccatcca aaaaatccag agtgtgatca gtacccacaa ttatatgatt
    14221 ttagcaattt gtaagatgct acattgaaac tttttgcttg attttaagca tgctttgtgc
    14281 tatagtaaat gataactaaa tattccttta aacctgtccc gtgaggcagg caaggagcgc
    14341 gataaagtag aagggtgaag tctatactgt gtgcagtagg gctcgcttgg ctataaattt
    14401 caagtctcct tgtttaagga gacttttctt tttggaggtt tgtcatgaaa acaaaagaag
    14461 ttgtagacga attgaccgtc aaacgagcga ttacgcgtat tacttatgag attatcgaac
    14521 gcaacaaaga tttgaataag atcgtcttgg ctggtattaa aactcgtggt gtctttattg
    14581 cccaccgaat ccaagaacgt ttgaagcagt tagaaaatct ttcagttcct gttgtggaat
    14641 tggatactaa acctttccgt gatgatgtta aaagtggaga agatacttct ttggtttctg
    14701 tcgatgtgac agaccgcgaa gttatcttgg tggatgatgt gctctataca ggtcgtacca
    14761 tccgtgctgc tattgataat attgtcggtc atggtcgtcc tgcgcgtgtg agtttagcag
    14821 ttctagtcga tcgtggacat agagaattgc caatccgtcc agattacgtt ggaaaaaata
    14881 tcccaaccag tcgttctgaa gaaatcatcg tagagatgac agaacttgat gaccaagaca
    14941 gagttctgat tactgaagaa gcttagaaag ttaaaggagt agccatgtca gaaaatcaac
    15001 aagcattgaa ccatgtggtg tccatggaag acctcactgt cgatcaagta atgaaattga
    15061 tcaagcgagg aattgagttt aaaaatggag cccagcttcc ctatgaagac catccgattg
    15121 tttccaatct cttctttgag gattctacac ggacacataa gtcctttgaa gtcgcagaga
    15181 ttaaacttgg attggaacga cttgactttg atgtgaagac tagctcggtt aataagggtg
    15241 agacacttta tgacaccatt ttgactctgt ctgctttagg agtggatgtc tgtgtgattc
    15301 gccatccaga ggtcgactac tatagagaat tgattgctag tccaacgatt acgacttcca
    15361 tcatcaatgg tggagatggt tcgggccaac accctagcca gagcttgctt gatttgatga
    15421 ccatttatga ggaatttggc cactttgagg gtcttaaagt tgctattgca ggtgacttgg
    15481 accactcacg cgttgccaaa tccaatatgc agattttgaa acgcttggga gctgaactct
    15541 ttttcgctgg acctgaggaa tggagaagtc aagagtttgc agactatgga cagtttgtaa
    15601 ccattgatga aatcattgat caggttgatg tcatgatgtt tctccgtgtg caacacgaac
    15661 gccatgatag tggagctgta ttttcaaaag aagactacca tgcccaacat ggcttgactc
    15721 aagaacgtta cgatcgtttg aaagaaacag caatcctcat gcacccagct ccaatcaatc
    15781 gtgatgtaga aatagcagac cacttggttg aagcaccaaa atcacggatt gtccaacaaa
    15841 tgaccaatgg tgtctttgtt cgaatggcaa tcttagaatc cgtactagcg agtagaaacg
    15901 ccaactaaaa cacaagacgt taaaagacgc cagtgagcgt ccacgagagg tgaaaatatg
    15961 acaaaaagaa ttctagtatt agaagatggc acagtttttg aaggcaaggc cttcggagca
    16021 gatattgatg taacaggcga aatcgtcttt aatacaggga tgaccggcta ccaagaatcc
    16081 attacagacc agtcttataa tggacaaatc ttgaccttta cttatccttt ggtaggaaat
    16141 tatggtatta atcgtgatga ttatgaatcc attattccaa cttgtaaggg agtcgttgtt
    16201 tttgaagaag cgcgtagagc tagcaactgg cgcaaccaaa tgaccttgga tgaatttttg
    16261 aaagccaaga aaattccagg gatttcagga attgatacgc gtgctcttac caagattatc
    16321 cgtaagcatg gtactatgcg tgcaaccttg acccatgttg gggacagtat ggaccatgtg
    16381 acggaccagc tccaagcaac agttttaccg acagacaata tcaaacaggt ttctactaaa
    16441 acgtcttatc cagctccagg agttggtttg agcgtggtgc tagtggactt tggtctcaag
    16501 cactcaatcc tacgtgaact ttctaaacgc aactgtaacg tgacagttgt tccttattcg
    16561 acaacggctg aagaaattct ccatctcaat cctgacggag ttatgttgtc aaatggtcca
    16621 ggtaacccag aagacgttcc acaagcactc gacatgattc gcggtgtaca aggaaaaatt
    16681 ccaatctttg gtatttgtat gggacaccaa ctctttgcaa tggcaaacgg ggctaagacc
    16741 tataagatga agtttggcca ccgtggattc aaccatgcgg tacgtgaaat cgcaacagga
    16801 cgagtagact tcaccagcca gaaccatggt tatgcagtca gccgcgagga tttgccagag
    16861 cacttgatta ttacccacga agaaatcaat gacaagtcag tggaaggtgt gcgccacaga
    16921 taccaacctg ctttctctgt tcaataccac ccagatgcag ctcctgggcc acacgacgct
    16981 agctacctat ttgacgagtt tatcgagatg atggaagttt ttaaacaatc aaactaagaa
    17041 cgagtaaaag ctcgtcggag aatttatgta actgaacacg gacggaaagc tcagaattta
    17101 gagaaaccaa cttggattgt caatccttcc ttgatttctt aaaattcaat cgctttctat
    17161 tcgtcctttg tatcttattt aatgtcgccc tgagaggcga cgaatagaaa ggagaagggt
    17221 gctccgtatt tgctgaactg aatacgggct acggacggtg ctaaaaagat agttattcct
    17281 agaactgaca gttcttcgtc ataactccta ttttagcttt gtccgcttga cgcccttaat
    17341 atcttatata tgcctaaacg tactgatatt caaaaaatta tggtgattgg ttctggtccg
    17401 attattattg gtcaggctgc tgagtttgac tacgctggga cccaggcttg cttgtcgttg
    17461 aaagaggaag gttatgaggt tgttttggtt aactcaaatc ctgcaaccat catgacggac
    17521 aaggaaattg ctgacaaggt ttacattgaa ccgattacac ttgagtttgt gacacgtatt
    17581 cttcgtaagg aaggtccaga tgccttgcta ccaacactcg gtggtcagac aggtctcaac
    17641 atggccatgg aattgtctaa aaatggcatc ttagatgagc ttggtgtaga gcttctcggt
    17701 actaaattgt ctgccattga ccaagcggag gaccgtgacc tctttaaaca attgatggaa
    17761 gagcttgagc aacccattcc agaatctgaa attgttaaca cagtagaaga agcagttgcc
    17821 tttgcagcga caattggcta cccagtcatc gttcgtccag cctttaccct tggtggtact
    17881 ggtggtggta tgtgtgccaa cgaaaaagaa ttgcgtgaaa tcactgaaaa tggtttgaaa
    17941 ttgtcacctg ttacccaatg tttgattgag cgttcgattg ccggtttcaa ggaaattgaa
    18001 tacgaagtga tgcgtgactc agctgacaat gccttggttg tttgtaacat ggaaaacttt
    18061 gacccagttg ggattcacac aggggattcc attgtatttg cccctgcgca aaccatgtca
    18121 gactatgaaa accaaatgct tcgtgatgcg agcttgagca ttattcgcgc cctcaagatt
    18181 gaaggtggat gtaatgttca gctagctctt gatcctaaca gcttcaagta ttatgttatc
    18241 gaagtaaacc ctcgtgtatc acgttcgtca gcccttgctt ctaaagcgac aggatatccg
    18301 attgctaagt tggctgccaa gattgcagta ggtttgacct tggatgaggt tataaaccca
    18361 gttacaggtt caacctatgc catgtttgaa ccagcccttg actacgtagt tgctaagatt
    18421 ccacgtttcc catttgacaa gtttgaaaag ggtgaacgcc gtctcggtac acaaatgaag
    18481 gcgactggag aagtcatggc aatcggtcgt aacatcgagg aatctcttct caaggcctgc
    18541 cgctcccttg aaattggggt gcaccacaat gaaatacctg aacttgcagc agtttctgat
    18601 gatgccttga ttgaaaaggt tgtcaaagcc caagatgacc gtctcttcta cgtatcagaa
    18661 gccattcgtc gtggctacac acctgaagaa attgcagagc ttacaaaaat tgatatcttc
    18721 tatcttgata aactcttgca tatctttgaa attgagcaag aattgggtgc tcatccacaa
    18781 gatctagaag ttttgaaaac agccaaactt aatggtttct cagaccgtaa gattgctgaa
    18841 ctctggggaa cgactgatga tcaagttcgc caacttcgct tggaaaacaa gattgttcca
    18901 gtttataaga tggtagatac ttgtgcggca gagttcgact ctgaaacgcc atatttctat
    18961 tcaacctatg gttgggaaaa tgaatctatc agatctgata aagaatctgt acttgtccta
    19021 ggttcaggtc caatccgtat cggtcaaggg gttgagtttg actacgcaac cgttcactct
    19081 gttaaggcta tccaggcagc tggttatgaa gctatcatca tgaactcaaa cccagagacc
    19141 gtttcaacag acttctctgt atcagataag ctttactttg agccattgac attcgaagat
    19201 gttatgaacg tcattgactt ggaacaacca aagggagtta tcgttcagtt tggtggtcaa
    19261 acagccatca accttgcgga gccattggca aaagcaggtg tgaccatcct tggtacacag
    19321 gttgctgacc tagaccgtgc cgaagaccgt gacctcttcg agcaagctct caaagaattg
    19381 gatattccac agccaccagg acaaacggct accaatgaag aagaagcagc tcttgcagct
    19441 cgtaagattg gcttcccagt tcttgtccgc ccatcttatg tacttggtgg acgtgccatg
    19501 gaaatcgttg aaaacgaaga agaccttcgt tcttacatgc gaactgctgt taaggctagt
    19561 ccagatcacc cagttcttgt cgactcttat atcgttgggc aagagtgcga agttgatgcc
    19621 atttcagatg gtaaagatgt actcattcct ggtatcatgg agcatatcga acgtgctggt
    19681 gtccactcag gtgactcaat ggctgtttac ccaccacaaa ccttgtcgca aaaggttcag
    19741 gagaccatcg cagactacac caaacgctta gcaatcggtc ttcactgcct tggaatgatg
    19801 aacatccagt ttgttatcaa ggatgaaaaa gtctacgtta ttgaggtcaa tccacgtgcc
    19861 agccgtactg ttccattcct atctaaggta accaatattc ctatggctca agtagcgacc
    19921 aagctcattc ttggtcaaag tttatcagaa cttggctacc aaaatggact ttaccctgaa
    19981 agcacccgtg ttcatatcaa ggcacctgtc ttctccttta ccaaactagc taaggtagac
    20041 agcttgctcg gtcctgaaat gaagtcaaca ggtgaagtta tgggttctga tgctactttg
    20101 gaaaaagctc tctataaagc ctttgaagct tcttatctac acttgccaac ttttggtaat
    20161 gtcgtcttta ccatcgctga tgatgccaaa gaagaagcct tgaacttggc tcgtcgtttc
    20221 caaaacattg gttatggaat ccttgcgaca gaagggacag cagccttctt tgctagtcat
    20281 ggcttgcaag cccaacctgt tggtaagatt ggtgatgacg ataaggatat cccaagtttt
    20341 gtacgcaaag gaagaattca agctatcatt aacacagtag gaacaaaacg aactgctgac
    20401 gaagatggtg agcaaattcg tcgttcagcc attgaacacg gggtgcccct cttcacagcg
    20461 ctagatacag ctaatgccat gcttaaggta cttgaaagtc gtagctttgt tacagaagcg
    20521 atttaaatag aaaaataaga tata
//
LOCUS       DAVLZS010000036        18861 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLZS010000036 DAVLZS010000000
VERSION     DAVLZS010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18861
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.036"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            122..277
                     /locus_tag="VYO88_001425"
                     /pseudo
     CDS             122..277
                     /locus_tag="VYO88_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            477..3752
                     /gene="rexB"
                     /locus_tag="VYO88_001426"
     CDS             477..3752
                     /gene="rexB"
                     /locus_tag="VYO88_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1719510.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLATYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3749..7399
                     /gene="addA"
                     /locus_tag="VYO88_001427"
     CDS             3749..7399
                     /gene="addA"
                     /locus_tag="VYO88_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1719511.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSAQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDTKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQVYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKIQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVQENLYEKLVNTQKQVS
                     SQKVLIHSTLAEKLNQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIGMINQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMDTGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNIRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(7361..7528)
                     /locus_tag="VYO88_001428"
     CDS             complement(7361..7528)
                     /locus_tag="VYO88_001428"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719512.1"
                     /translation="MDRTDEVSSKHCFEVVDRTDEVSNHIYSKAKLTWFEEIFEEYKL
                     YFYNLNLVFTE"
     gene            7704..8882
                     /locus_tag="VYO88_001429"
     CDS             7704..8882
                     /locus_tag="VYO88_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719513.1"
                     /translation="MTLPVRKSLHDAVLQASKANTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            9091..15126
                     /locus_tag="VYO88_001430"
     CDS             9091..15126
                     /locus_tag="VYO88_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1719514.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYHEETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKPKEQGPEKTEEVPVK
                     PTEETPVNPNEGATEGTSIQGAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPENNDSKNENSEKTGEEVPVNPNEGTVEGTSNQETENPVQPAEESTTNS
                     EKVSPDTSSENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEP
                     SNGNSTEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLELRNVSDLELYSLSN
                     GTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKL
                     QQEIESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANEVEL
                     STDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFESLRGATIEKLSLKNVSISGKDD
                     IGSLANEAQNNTKIKQVHVDGVLAGERGIGGLLAKADQSSITESSFKGRIVNTYETTA
                     SYNIGGLVGHLTGSKASLTKSKATVVISSNTNSSDQTVGGIAGLVDKDAHIQNSYSEG
                     DINNSQRFGKVAGIAGNLWDRESNSENHAGRLTNVLSDVNVTNGNAISGYHYNGMKIT
                     DAFSNKANKVFNVTLEKDEVVSKESFEERGTMLEASQIASKKAEINLLTPPIVEPLST
                     SGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKELLSA
                     VMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQDDFANLAEYSIGDSGLLYT
                     PNQFLYDQDSIINQVLPELQQVAYDSEAIRKTLGISPEVKQTELYMEDQFTKTKQDLA
                     NRANSLKKLLSADAGLASANPVTEGYLVDKIKRNKEALLLGLTYLERWYNFSYGQVNV
                     KDLVLYHLDFFGKGNASPLDTLIELGKSGFNNLLAKNNVDTYGISLASQHGTTDLFST
                     LEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLASTKYSIGVYDRITSD
                     SWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLNSFVEKSAHET
                     AERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTDHTEGKATEVADFDSPNPAMK
                     HFFGPVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYG
                     RRSGLGPEFFAKGLLQAPDQPSDATITINSILKHKTSDSTEGQRLQVLDPTTRFNDAA
                     DLQNYVHNMFDVVYMLEYLEGQSIVKQLDAYQKMTALRKIENKYVKDPADGNEVYATN
                     VVKELTEEEARNLNSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSSEKG
                     TPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEGIAKQNGQTINLYGKKQGLVTDKLV
                     LEKIFSGKYPSWTAFKKAMYQERIAQFDHLTKVIFKDPTKPWPSYGTKTINNVDELQK
                     LMDEAVLQDATGTRWSNYNPETDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            15178..15354
                     /locus_tag="VYO88_001431"
     CDS             15178..15354
                     /locus_tag="VYO88_001431"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1719515.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            15573..16424
                     /gene="ylqF"
                     /locus_tag="VYO88_001432"
     CDS             15573..16424
                     /gene="ylqF"
                     /locus_tag="VYO88_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1719516.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            16411..17208
                     /locus_tag="VYO88_001433"
     CDS             16411..17208
                     /locus_tag="VYO88_001433"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1719517.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKSLVLGKKES"
     gene            17224..18775
                     /locus_tag="VYO88_001434"
                     /pseudo
     CDS             17224..18775
                     /locus_tag="VYO88_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
BASE COUNT         6162 a         3656 c         3910 g         5133 t
ORIGIN      
        1 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagcaatat
       61 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      121 gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg aattagagtc
      181 cgatgttgat ggcgataaat cagacaatct acccgtcgac attaagatac tgggacaaca
      241 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagtctt gttaccgagg
      301 cttttttatt atgtgatttt cagtagccag acttattcta tctaatacaa gtaaagctaa
      361 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      421 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      481 aattacttta tactgatatt cgaacttctt tgacagaaat tctaacaaga gaggcagaag
      541 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      601 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      661 gctttgctca aatggctcgt tatctggtct tgaatgattt accagttaaa actactcttg
      721 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      781 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      841 accatgagat gaccaaatct cagatgagtt ttttggactt ggagaattta acagatgagg
      901 ataagaggac ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaaggtc
      961 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaaggtaa
     1021 gtagtgattt taatcaaatc accttggtca ttgacggctt tactcgtttt tctgctgagg
     1081 aagagcgggt tgtggactta cttcacggca aaggtgttga gattgttatc ggggcttatg
     1141 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa gccagcgtaa
     1201 aatttctcca tcatctggct tctaaatacc aaacgcctgc tcaggactgt tctcaaactc
     1261 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1321 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1381 tgacgcaaaa ggaggagttg gagctagtag cccgtagcat tcgtcagaaa ttacatgaga
     1441 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1501 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1561 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1621 gttttcgtca ggaggatttg attaatcttc ttagaactga tttgtatact gacctcagtc
     1681 agtctgatat tgatgctttt gagcaatata tccgctatct tggtatcaat ggcttgccag
     1741 cctttcagca aaccttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1801 tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga aaacaaaagg
     1861 ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg accaagcagt
     1921 tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc gaagtttgga
     1981 aggctttctg ccatgtttta gaacaatttg cgactgtttt tgctggttca caggttagtc
     2041 tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac cgtaccattc
     2101 cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca ttgactgctg
     2161 actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct caaaacacca
     2221 gtcttctgac agatgaagaa aggcaaaacc taaaccaaac gaccgaagaa ggcgttcaat
     2281 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tccttggtca
     2341 attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa agtgaaagta
     2401 aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga gagaagagga
     2461 tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt ttgtctagtc
     2521 tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg acttttgtca
     2581 aggttctgtc gcgtgtcata ggtaaaaaac tagatctgca aggtctggaa aatccagcta
     2641 tcccaaccag tccaagcagc aagaccttag ccaaggacac cttgcaagct ctctatcctg
     2701 ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc aatgaataca
     2761 gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcgt cctgatgccc
     2821 gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttacagttg cctaatgaag
     2881 attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa cgcgaatttg
     2941 aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg cttgatgttg
     3001 cacggacgac tggacatatt ctccgacaca atccagccat cgaaaccatc aaagaagaag
     3061 caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc agtgtctttg
     3121 tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata ggagtagtag
     3181 actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3241 agttagcaac ctatcttgct gccctaaaaa gagaagggga gcagaacttt ttcggcgcca
     3301 tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3361 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3421 gttatttagg cgaattttat aacaaaaaca aggctaatca actgacagat gaggaatttc
     3481 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3541 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3601 aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctag
     3661 aaaagttgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag caagcttggc
     3721 ttgaaaaaat aagagaggag ttgaatcgat gaagcttatt ccctttttaa gtgaggagga
     3781 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga aaactgccga
     3841 gcaaatcgaa gctatctaca cttctgccca gaatatcctg gtctcagcat cggctggttc
     3901 tggaaagacc tttgtcatgg cagagcgcat tctggaccaa ttggcgcgtg gtgtcgaaat
     3961 ttctcaactc tttatctcaa cctttaccgt caaggctgca actgaactta aagaacgttt
     4021 agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgacctca aacaacactt
     4081 gggtcgccag ttggcagacc tacccaacgc tgccattgga accatggatt ctttcacaca
     4141 aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc gtattttaca
     4201 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4261 ttaccaaggt aaacagaaag agacctttag tcatttgctg aaaaactttg ctgggcgtgg
     4321 caaggacgaa cggggtctgc gccagcaggt ctataaaatc tatgacttcc tccaatccac
     4381 cagtaatcct caaaaatggc tgagtgaatc tttcctcaaa ggatttgaga aagctgattt
     4441 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctttggg atttggaaag
     4501 ctttttccgt taccatctgg ataacgatac caaggagttt gcaaaggctg cctatttaga
     4561 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagtccg atagtcaggt
     4621 ttatcaggca gtgcttgcgc gtgttgtcgc catctctaag gagaaaaacg gtcgagctct
     4681 gactaatgcc agccgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4741 aaagatccag tttactaaac taggacaatt atcagaccag atagcgattc tcgactatca
     4801 agaacgttat catggagaca cttggaaact agctaaaacc ttccaatctt tcatgagcga
     4861 ttttgtagag gcttatcgtc agagaaaacg acaggaaaat gcctttgaat tcgctgatat
     4921 cagccattac accattgaga ttttagagaa tttcccacaa gttcgtgagt cttatcagga
     4981 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacgaat
     5041 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5101 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5161 aaatccccaa gaaggcaagc tcattctcct caaggaaaat ttccgtagta gttcagaagt
     5221 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5281 ctatgataac aagcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5341 caaggcagaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5401 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga aacttcatca
     5461 agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca gtcgtaatga
     5521 ccagattctc ctcgccctgt ctgagtacgg aattcctgtc aaaactgacg gtgaacaaaa
     5581 caattatctc caatccctag aagtgcaagt catgctagat acccttcgtg tcattcacaa
     5641 tcccctgcaa gactacgcct tggttgctct tatgaagtct ccaatgtttg gttttgatga
     5701 ggacgagtta gcacgtttgt ctcttcagaa agcagaggat aaagtccaag aaaatcttta
     5761 tgagaaacta gtcaatactc aaaaacaggt aagtagccaa aaagtcttga ttcactcaac
     5821 tctagctgag aaactaaacc aattcatgga tatattggct tcttggcgcc tgtatgccaa
     5881 aacccactcc ctctatgact tgatttggaa gatttacaac gaccgttttt actacgatta
     5941 tgttggagct ttgccaaatg gtcctgctag acaggccaat ctctatgccc tagcactgcg
     6001 tgctgatcaa tttgaaaaga gcaatttcaa gggcttgtcg cgttttattg gtatgattaa
     6061 ccaagtttta gaagcccagc acgatttggc aagtgttgca gttgcaccac ctaaggacgc
     6121 agtagagctt atgaccatcc acaagagtaa agggctggag tttccttatg tctttatcct
     6181 caatatggat caagatttca acaagcaaga ctctatgtca gaggtcattc tcagccgtca
     6241 gaatggtctt ggtgtcaagt atattgccaa gatggataca ggagcagtgg aagatcacta
     6301 tcctaaaacc atcaaactct ccattcctag cctgacctat aggcagaacg aagaggaatt
     6361 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6421 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaatcca aggaataccc
     6481 agcagccaaa aatgggaaac taaatagcaa tattagactg caagcacgga atttccaaga
     6541 ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6601 tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca agagtcctct
     6661 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaat
     6721 gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6781 tcaaactcca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6841 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc tttgatttgc cagatttttc
     6901 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagag
     6961 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacaagttca
     7021 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7081 agcactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7141 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7201 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7261 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7321 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7381 tcaagttgta aaagtatagc ttatactctt cgaaaatctc ttcaaaccac gtcagcttcg
     7441 ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     7501 ttgagctgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt
     7561 cagttctatc tacaacctca aaacagtgtt ttgagctgac ttcgtcagtt ctatctacaa
     7621 cctcaaaaca gtgttttgag ctgactgcgg ctagctttct agtttgctct ttgattttta
     7681 ttgagtatta gaaaggagac ctcatgacac ttccagttag aaaatccctg cacgatgcag
     7741 ttttacaggc ttcgaaagcg aatacttggg aacaagctac caaggaatgg aatgaagttt
     7801 ccttgatttt taacggtatc ggccgtagca attgtgtctg tggaaatgcc atcaaatacg
     7861 cttatgaact ctttaacggt gtcacaggcc aacgcctctt tccaattggt agcgactgtg
     7921 ttcgtcattt tcatcgattg tcccttgacc agcaattgga agaggaagaa aaactgctca
     7981 gaaaggttga aaatctaacc agaaaagctc agaaaaagga aaaaatcaag gtcaataaaa
     8041 gtgactttga cgagcgactt ctaaaatggc tctgggaaaa aggtgttttc aaacccaatc
     8101 gtggcaatca atttgcgcct gagagagact accagctttt cctagaagtc tttcagggag
     8161 gaagttggac caaggcggaa ccaaagaaaa aggctcggat ggaagaagtc cttgaaaagt
     8221 gtatcaaacc ctttttactt gggaaatcgg atgaccaact ctaccttgtc aagctaggca
     8281 aggagaaaat tgactacgaa caagaactcc gtatccaggc agagaaagaa cgcaagaaga
     8341 gggataaaat cgccaagcaa tatgcagaca atctggttct agccatggga cccgcagagc
     8401 gtgcttatca agattacttt ggctttacag agaccctgac tcaagaagaa cgcaagtggg
     8461 aaaaaattct ttttggtaaa aatagagcag aacgagctat caaggccaaa caataccaaa
     8521 aagagctgga aaaagaccaa cgaattgcca gtcaggatcc aattgaaaga aaacagaagc
     8581 agacttggat cctcaattcc tattttcgtg agcttcctga agaaaaagct cgattttcta
     8641 gactcttatt agaatatcga aaaagtggtg aagtaccctt ttcaactgaa tacctgtcag
     8701 atcatctcat cgactttttc tataaaatga aagcctttga atttgaaatc gcaccagaac
     8761 aagtccgaga ttttctaaaa aaaagcctgc aggaagacca tcgctcatca gcacaaggaa
     8821 gctggataga aggaattctc ctcaactgcc tcaaaccatt tttagaacga ttagtgatat
     8881 gagtaacacc taccgtgtaa atttcatggt aggtgttatt gtacccccaa ataatataaa
     8941 acaaagtatg aaagcgcatc tcaattttaa gacttttttg taaattaaga gtataattaa
     9001 ggtatactgc cttttctata gataatagat aatacactaa tataataaag gtctttgtaa
     9061 catatataaa ttttatttca aggaggaata atggaaaagt attttggtga aaaacaagag
     9121 cgtttttcat ttagaaaatt atcagtagga cttgtatctg caacgatttc aagtttattt
     9181 tttatgtctg tattagctag ttcatctgtg gatgctcaag aaactgcggg agttcactat
     9241 aaatatgtgg cagattcaga gctatcatca gaagaaaaga agcagcttgt ctatgatatt
     9301 ccgacatacg tggagaatga tgatgaaact tattatcttg tttataagtt aaattctcaa
     9361 aatcaactgg cggaattacc aaatactgga agcaagaatg agaggcaagc cctagttgct
     9421 ggtgctagct tagctgctct gggaatttta atttttgctg tttccaagaa aaaggttaag
     9481 aataaaacgg tattacattt agtattggtt gcgggaatgg gaaatggtgt cttagtttca
     9541 gtccatgctt tagaaaatca tcttttgcta aattacaata cggactatga attgacctct
     9601 ggagaaaaat tacctcttcc taaagagatt tcaggttaca cttatattgg atatatcaaa
     9661 gagggaaaaa cgacttctga ttttgaagta agtaatcaag aaaaatcagc agccactcct
     9721 acaaaacaac aaaaggtgga ttataatgtt acaccaaatt ttgtagacca tccatcaaca
     9781 gtacaagcta ttcaggaaca aacacctgtt tcttcaacta agccgacaga agttcaagta
     9841 gttgaaaaac ctttctctac tgaattaatc aatccaagaa aagaagagaa acaatcttca
     9901 gattctcaag aacaattagc cgaacataag aatctagaaa cgaagaaaga ggagaagatt
     9961 tctccaaaag aaaagactgg ggtaaataca ttaaatccac aggatgaagt tttatcaggt
    10021 caattgaaca aacctgaact cttatatcat gaggaaacta tagagacaaa aatagatttt
    10081 caagaagaaa ttcaagaaaa tcctgattta gctgaaggaa ctgtaagagt aaaacaagaa
    10141 ggtaaattag gtaagaaagt tgaaatcgtc agaatattct ctgtaaacaa ggaagaagtt
    10201 tcgcgagaaa ttgtttcaac ttcaacgact gcgcctagtc caagaatagt cgaaaaaggt
    10261 actaaaaaaa ctcaagttat aaaggaacaa cctgagactg gtgtagaaca taaggacgta
    10321 cagtctggag ctattgttga acccgcaatt cagcctgagt tgcccgaagc tgtagtaagt
    10381 gacaaaggcg aaccagaagt tcaacctaca ttacccgaag cagttgtgac cgacaaaggt
    10441 gagactgagg ttcaaccaga gtcgccagat actgtggtaa gtgataaagg tgaaccagag
    10501 caggtagccc cattgccaga atataagggg aatattgagc aagtaaaacc tgaaactccg
    10561 gttgagaagc cgaaagaaca aggtccagaa aaaactgaag aagttccagt aaaaccaaca
    10621 gaagaaacac cagtaaatcc aaatgaaggt gctacagaag gaacctcaat tcaaggagca
    10681 gaaaatccag ttcaacctgc agaagaatca acaacgaatt cagagaaagt atcaccagat
    10741 acatctagcg aaaatactgg ggaagtgtcc agtaatccta gtgattcgac aacctcagtt
    10801 ggagaatcaa ataaaccaga aaataatgac tctaaaaatg aaaattcaga aaaaactgga
    10861 gaagaagttc cagtaaatcc aaatgaaggc acagtagaag gtacctcaaa tcaagaaaca
    10921 gaaaatccag ttcaacctgc agaagaatca acaacgaatt cagagaaagt atcaccagat
    10981 acatctagcg aaaatactgg ggaagtatcc aataaaccta gtgattcaaa accaccagtt
    11041 gaagaatcaa atcaaccaga aaaaaacgga actgcaacaa aaccagaaaa ttcaggtaat
    11101 acaacatcag agaatggaca aacagaacca gaaccatcaa acggaaattc aactgaggat
    11161 gtttcaacca aatcaaacac atccaattca aatggaaacg aagaaattaa acaagaaaat
    11221 gaactagacc ccgataaaaa ggtagaagat ccagagaaaa cacttgaatt aagaaatgtt
    11281 tccgacctag agttatacag tttgtcaaat ggtacttata aacaacacat ttcgttagaa
    11341 caagttccaa gcaatccaaa tagctacttt gttaaagtga aatcttcttc attcaaagat
    11401 gtatacctac cagtagcatc aatatcagag gaaagaaaaa atgataaaat cctttataaa
    11461 atcacagcaa aagtagagaa gcttcagcag gagatagaaa gcagatataa agataatttt
    11521 accttctatc tagctaagaa gggaacagaa gaaacaacaa actttacttc ctttagtaat
    11581 ctggtcaaag ctataaacca aaatctctct ggaacctatc atttaggagc tagcctgaat
    11641 gctaacgaag tggagcttag cactgatgat aaatcctata tcaagggaac ctttactggt
    11701 cagttgattg gtgaaaaaga tggtaagcat tatgctattt acaacttgaa aaagcctctt
    11761 tttgaaagct tgagaggggc cacaatagaa aagttgagtc tgaaaaatgt ctctatttca
    11821 gggaaagatg atatcggttc actggcaaat gaagctcaga ataacacaaa aattaagcaa
    11881 gttcatgtgg atggtgtact tgccggtgaa cgtggtatcg gtggtttgtt ggctaaggca
    11941 gatcaatcaa gcatcacaga gagtagtttc aagggaagaa ttgtcaatac ctatgaaaca
    12001 actgcttcct ataatatcgg tggcctggtc ggtcatttga caggaagcaa agcttcactg
    12061 actaagtcaa aagcgacagt ggtcatttca tcaaatacaa atagttctga ccagaccgtt
    12121 ggaggtatcg ctggtcttgt agacaaagat gcgcatattc agaatagcta ttctgaaggg
    12181 gatattaata atagccaacg ttttggaaaa gttgctggta tagcaggtaa cttatgggat
    12241 cgtgaatcaa atagtgaaaa tcatgctgga agattgacta atgtgcttag tgatgtcaat
    12301 gtaactaatg gaaatgccat tagtggttac cattataatg gaatgaaaat tactgatgca
    12361 tttagtaata aagcgaataa agttttcaat gtcactttag agaaggatga ggtcgttagc
    12421 aaagaatcct ttgaggaaag aggaacaatg ctagaggctt ctcaaattgc aagcaaaaaa
    12481 gcagaaatca atcttctcac tccaccaata gtggaacccc tctcaacaag cggtaagaaa
    12541 gacagtgatt tttctaagat agcccattat caagccaacc gtgctttggt ttataagaac
    12601 attgaaaaat tgttaccttt ctataacaag gcgaccatcg tgaaatacgg aaacctggtt
    12661 aaggagaaca gtatcttata tcaaaaagaa ctcttgtctg cagttatgat gaaggatgac
    12721 caagtaatca cagatattat ttccaacaaa cagactgcaa acaaactctt gcttcactac
    12781 aaggaccatt catctgaaaa gtttgatctc aggtaccagg atgattttgc caatttggca
    12841 gaatatagca ttggagatag tgggcttctc tatacgccaa atcaattctt gtatgaccaa
    12901 gactctatca tcaatcaagt tttacctgaa ttacagcagg ttgcctacga ttcagaagct
    12961 atcagaaaga cactcggaat ttctccagag gtcaagcaaa ctgagctcta tatggaagac
    13021 cagtttacca aaacaaagca agatttggca aacagggcaa acagtttgaa aaaactcttg
    13081 tctgcggatg ctggactggc tagtgctaac ccagtcactg aaggttatct tgtagataaa
    13141 atcaaacgca acaaggaagc cttgctactt ggcttgacct atctggaacg gtggtataac
    13201 tttagctatg gtcaggtgaa tgtcaaagac ctagttctgt accatttgga cttctttggt
    13261 aaggggaatg cttcaccatt agatactctg attgagttgg gtaaatctgg ctttaacaat
    13321 cttctagcta agaataatgt cgatacttat ggtatcagtc ttgccagtca acatggaacg
    13381 acagatttgt ttagcacgct ggaacattac cgaaaagtct ttttaccaaa tacaagcaat
    13441 aatgactggt ttaaatcaga gactaaggct tacattgtcg aagaaaaatc cactatcgaa
    13501 gaggtgaaaa cgaagcaagg gttagctagc accaagtatt ctatcggtgt ttatgatcgt
    13561 atcactagcg acagctggaa ataccgtaat atggtactac ctctacttac cttgccagaa
    13621 agatccgtat ttgtcatttc aaccatatct agtctaggtt ttggtgctta tgatcgctat
    13681 cgtaataaag aacatcaagc aaatggtgat cttaatagct ttgttgaaaa gagtgctcac
    13741 gaaacagcag agcgtcaacg agatcactat gattattggt atcgtattct agatgaaaaa
    13801 gggcgtgaaa agctttatcg aaatatcttg ctttatgatg cctataaatt tggaactgat
    13861 catactgaag gaaaggctac agaagtagca gattttgata gtccaaatcc tgcaatgaaa
    13921 catttctttg gacctgttgg aaataaggtt ggacataatg gacatggtgc ttatgctaca
    13981 ggggatgccg tttattatat gggttatcgt atgttggaca aggacggcgc cattacttat
    14041 acgcatgaga tgacacatga ctcagatcag gacatttatc ttggaggtta tggaagaaga
    14101 agtggacttg gacctgagtt ctttgctaaa ggcttactac aagcaccaga ccaaccaagt
    14161 gatgcaacca ttaccatcaa ctctatcttg aaacataaaa catcagatag tacagaaggt
    14221 cagcgattgc aagtacttga tccaactaca agatttaatg acgcagcaga tcttcagaac
    14281 tacgtccaca atatgtttga tgtcgtttac atgttggaat atctcgaagg gcaatctatc
    14341 gtgaaacagt tagatgctta tcagaaaatg acggccctga gaaaaatcga gaataaatac
    14401 gtgaaagatc ctgcagatgg aaatgaggtt tacgctacta acgtagtcaa agaattgaca
    14461 gaagaagagg cccgaaacct gaatagtttt gatagtttga ttgacaataa tattctttca
    14521 gctcgtgagt ataaggctgg tacatatgag agaaatggct actttactat aaaactcttt
    14581 gcaccaatct tttcagcatt gagcagtgag aaaggtactc ctggagatct tatgggacga
    14641 aggatagctt atgaactctt agctgctaaa ggatttaaag atggtatggt accatatatt
    14701 tccaaccaat atgaaggaat tgctaaacaa aatggtcaga caatcaacct ttacggtaaa
    14761 aaacaaggat tagtgacaga taagcttgtt ttggaaaaga tattctctgg caagtatcca
    14821 tcttggacag cctttaaaaa agctatgtat caagagcgta ttgctcagtt tgatcatttg
    14881 actaaagtta tttttaaaga tccgacaaaa ccatggccaa gctatggcac aaagactatc
    14941 aataatgtgg atgaattgca gaaactaatg gatgaagctg ttttgcagga tgctacaggt
    15001 acacgttgga gtaattataa tccagaaacg gacagtgccg tccataagtt gaagagagca
    15061 atctttaaag cctatcttga ccaaacaaat gattttagaa gttcaatttt tgagaataaa
    15121 aaatagtgtt tactattagg aaataaagtt taaaaaggtg atgaagaaca aaccaagatt
    15181 caagcaggaa ttcctactga taatgaagta agttatgctc ttatttatca gcaggaaact
    15241 cttcctgcaa caggttcatc aacttctgca cttacagctt taggcctatt agctgttggt
    15301 agtttagttc ttttggttca taatatgacg ggaacagttt tttgctccct ctgaaaagtc
    15361 atcatttgtt ggcttttttc tatataggct aaaagatagg gtaaaaggct atcatcggac
    15421 aaaataaaga aggcatgata taatataaag tagatttcta tgtcataaaa caagaactgt
    15481 ttggacatca ttcatttgaa aactctctat gttcaaacta tagtaaaata aaatagggga
    15541 tctaaatcct tgctacgaaa ggaaaaaact caatggctac tattcaatgg tttcctggtc
    15601 acatgtctaa agcgcgtcga caggtgcagg aaaatttaaa atttgttgat tttgtgacga
    15661 ttttagtaga tgcacgcttg cctctatcta gtcaaaatcc tatgttaacc aagattgttg
    15721 gtgataaacc aaaactcttg attttaaaca aggccgactt ggctgatcca gcaatgacca
    15781 aggaatggcg tcagtatttt gaatcacaag gaatccagac gctagctatc aactccaaag
    15841 agcaagtgac tgtaaaagtt gtaacagatg cggccaagaa gctcatggct gataagattg
    15901 ctcgccagaa agaacgtggg attcagattg aaaccttgcg taccatgatt attgggattc
    15961 caaacgctgg taaatcaact ctgatgaacc gtttggctgg taaaaagatt gctgttgttg
    16021 gaaacaagcc aggggtcaca aaaggtcaac aatggcttaa aaccaataaa gatctggaaa
    16081 tcttggatac accggggatt ctctggccta agtttgagga tgaaactgtt gcacttaagt
    16141 tggcattgac tggagctatc aaggatcagt tgcttcctat ggatgaggtt accatttttg
    16201 gtatcaatta tttcaaagaa cattatccag aaaagctggc tgaacgcttc aaacaaatga
    16261 aaattgaaga agaagcgcct gtgattatta tggatatgac ccgcgccctc ggtttccgtg
    16321 atgactatga ccgtttttac agtctcttcg tgaaggaagt ccgtgatggc aaactcggta
    16381 actatacctt agatacattg gaagacctcg atggcaacga ttaaagaaat caaagaactc
    16441 cttgtgacag tcaaggagtt agaaagccct atttttttag agcttgaaaa ggataatcgc
    16501 tcaggagttc aaaaggaaat cagcaagcgt aaaagagcca ttcaagctga attagatgaa
    16561 aatttgcgct tggaatccat gctttcttat gaaaaagaac tttataagca aggattgacc
    16621 ttaattgcag gtattgatga ggttggtcgt ggtcctcttg ctggtcctgt agtcgctgcg
    16681 gccgttattt tacctaaaaa ttgtaagatt aaaggtctca acgacagcaa gaaaattcct
    16741 aaaaagaaac atctggagat tttccaagcc gttcaagacc aagccttgtc gattggaatt
    16801 ggtatcatag ataatcaggt catcgaccaa gtcaacatct atgaagcaac caaactagcc
    16861 atgcaagaag caatctccca gctcagccct caaccagagc accttttgat tgatgccatg
    16921 aaactggact tgcccatttc acaaacctcc attatcaaag gagatgccaa ctccctctct
    16981 atcgcagcag catctatagt agccaaggta acacgtgatg aattgatgaa agaatacgat
    17041 cagcagttct ctggctatga tttcgctact aatgcaggat atggcacagc taaacatctg
    17101 gaaggcctca caaaactagg agttacccca attcaccgaa ccagctttga acccgttaaa
    17161 tcactggttt taggtaaatc actggtttta ggtaaaaaag aaagttaatt gaaaggaaat
    17221 accatggagg aacagtcgga aatagtccgt tctaagaaag aattcgcctt tgcatccagc
    17281 actatactat cccaagttgg tcgaggaatc attgtcggcc tcatcgttgg aattatcgtc
    17341 ggatcctttc gtttcttaat tgaaaagggc ttccacctga tacaaggagt ttatcaagat
    17401 caagggtact tagtgcgcaa tctttttgta ctggttttgt tttatatact catctgttgg
    17461 ctcagtgcca aactaacacg gtcagaaaaa gatattaaag gctcaggaat tcctcaagtc
    17521 gaagccgaac tgaaaggcct catgtccctc aactggtggg gcattctttg gaaaaaatat
    17581 gtgctaggta ttcttgctat tgccagtgga ctcatgctgg gtcgagaggg acccagcatt
    17641 caacttggag cagttggtgg taaaggaatt gccaagtggc tcaaatccag tccagtagag
    17701 gaacgttcct tgattgccag tggagctgca gcaggtttag ccgcagcctt taatgctcct
    17761 attgcagcac ttctctttgt tgtagaagaa gtctatcacc atttttcgcg ctttttctgg
    17821 gtctcaactc tagcagccag catcgtagca aactttgtgt ctctactcat gttcggtttg
    17881 acaccagtat tggatatgcc agataacatt cctcccatga ccctagacca gtattggata
    17941 tatctcgtca tgggaatttt ccttggattt tcaggttttc tctatgagaa agctgtatta
    18001 aacgttggaa gagtttatga cttgattggt caaaaaatcc atttggatag ggcttattat
    18061 cccatcttgg cttttatcct tatcatacca gtcggaatct tcttacctca aatcattggt
    18121 ggcggaaatc agcttgtcct ttctttaact gaacaaaatt ttagtttcca agttttatta
    18181 gcttactttt taatccgctt tatttggagt atgattagct atggaagtgg actgccagga
    18241 ggaattttcc tccccatttt agctcttggt tctttgcttg gtgccttagt tggtgttatc
    18301 tgtgtcaatc ttggacttgt cagtcaagag caattcccta tatttgtcat tctaggaatg
    18361 agtggctatt ttggagccat atcaaaagct cccttaaccg ctatgatcct cgtaactgag
    18421 atggtaggag atattcgcaa ccttatgcca cttggtcttg tcactcttgt ttcttatatt
    18481 atcatggatt tgctcaaagg tacgccaagt ctatgaagcc atgctggaaa aaatgcttcc
    18541 agaagaagta tctagcgaag gagaagttac acttatcgaa ataccagttt ctgataaaat
    18601 tgctgggaaa caagttcatg aactcaactt accacacaac gtcctcatca caactcaagt
    18661 ccataatggc aagagccaaa cagttaacgg ctcaaccaga atgtatctgg gtgatatgat
    18721 tcacctggtt attccaaaaa gtgaaattgg aaaagtcaaa gatttgttgt tgtagtatga
    18781 tcatttacat aatttatgct atgtaaatga tcagtttgat ttatttagaa aaccgattct
    18841 cagaaatgag atcggttatt t
//
LOCUS       DAVLZS010000037        17951 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLZS010000037 DAVLZS010000000
VERSION     DAVLZS010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17951
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.037"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(122..1972)
                     /locus_tag="VYO88_001435"
     CDS             complement(122..1972)
                     /locus_tag="VYO88_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1719518.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2014..3171)
                     /locus_tag="VYO88_001436"
     CDS             complement(2014..3171)
                     /locus_tag="VYO88_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1719519.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIKWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            3229..4395
                     /locus_tag="VYO88_001437"
     CDS             3229..4395
                     /locus_tag="VYO88_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1719520.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            4534..4860
                     /locus_tag="VYO88_001438"
     CDS             4534..4860
                     /locus_tag="VYO88_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1719521.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            4847..5440
                     /locus_tag="VYO88_001439"
     CDS             4847..5440
                     /locus_tag="VYO88_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1719522.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5433..6344
                     /locus_tag="VYO88_001440"
     CDS             5433..6344
                     /locus_tag="VYO88_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1719523.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6407..7468
                     /locus_tag="VYO88_001441"
     CDS             6407..7468
                     /locus_tag="VYO88_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719524.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIAS
                     FFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIILL
                     FFVAEVALIGDYLRILAFL"
     gene            complement(7540..8400)
                     /locus_tag="VYO88_001442"
     CDS             complement(7540..8400)
                     /locus_tag="VYO88_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV1719525.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFAIVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIYLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(8522..9508)
                     /locus_tag="VYO88_001443"
     CDS             complement(8522..9508)
                     /locus_tag="VYO88_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1719526.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9780..11255)
                     /locus_tag="VYO88_001444"
     CDS             complement(9780..11255)
                     /locus_tag="VYO88_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1719527.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11513..12436)
                     /locus_tag="VYO88_001445"
     CDS             complement(11513..12436)
                     /locus_tag="VYO88_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1719528.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12450..13379)
                     /locus_tag="VYO88_001446"
     CDS             complement(12450..13379)
                     /locus_tag="VYO88_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1719529.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(13698..13919)
                     /locus_tag="VYO88_001447"
     CDS             complement(13698..13919)
                     /locus_tag="VYO88_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719530.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            complement(13873..14133)
                     /locus_tag="VYO88_001448"
     CDS             complement(13873..14133)
                     /locus_tag="VYO88_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719531.1"
                     /translation="MTGVSNPTTDSAPLVLAEAKKAFADDSLIEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            complement(14559..14714)
                     /locus_tag="VYO88_001449"
                     /pseudo
     CDS             complement(14559..14714)
                     /locus_tag="VYO88_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(14899..15510)
                     /gene="rpsD"
                     /locus_tag="VYO88_001450"
     CDS             complement(14899..15510)
                     /gene="rpsD"
                     /locus_tag="VYO88_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1719532.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(15705..16757)
                     /locus_tag="VYO88_001451"
     CDS             complement(15705..16757)
                     /locus_tag="VYO88_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1719533.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(16754..17452)
                     /locus_tag="VYO88_001452"
     CDS             complement(16754..17452)
                     /locus_tag="VYO88_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719534.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(17619..>17951)
                     /locus_tag="VYO88_001453"
     CDS             complement(17619..>17951)
                     /locus_tag="VYO88_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1719535.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT         5340 a         3862 c         3323 g         5426 t
ORIGIN      
        1 aaccatatac ggcaaggcga cgttgacgtg gtttgaagag attttcgaag agtataagtc
       61 tctacataat aaaacgcata ttaccaaggt tgtgtaactt gatactatgc gtttttcttt
      121 tttattcaat gtgggttgtt tgattagcaa aggcgataat agcttgcttc aactcatctc
      181 cactgagagt gcggaactct ccaatctttt gattgatgga ttctaaaggc atgacattaa
      241 ccttaccaac gaaaatctta tccataactt gattatcaac gagttcggtt gataccaaga
      301 gttcttcgta gagtttttca cctgggcgga ttccaacttc aacgattgga atttcacttt
      361 cagtgtggcc acttagaagc accatcttct tggccaagtc ataaatcttg actggtttgc
      421 ccatatcaag gataaagact tccccatctt tggcataagc accagcatgg ataaccagac
      481 ggctagcttc tggaatggtc ataaaataac gggtcatgcg gaagtctgtc accgttacag
      541 gcccaccttc agcaatctga cgttcaaaga ctggaatgac actaccacgg ctaccaagaa
      601 cattcccaaa acgaactgca cagtaggttg attggctacg ttggttaaag ccagtgacaa
      661 tcaactccgc cacgcgcttg gttgctccca taacatttgg tggattgact gccttatctg
      721 tcgaaatcat aaccatctta gacactttag cttcatcaac agccttagca acattgtaag
      781 ttccacggat attgtttttg aaggcttctt ttggattgcg ctccatcata ggaacatgct
      841 tgtgggctgc cgcatgataa acaatagcag gtttgtactg ctcaaagact tgcaacaaac
      901 gatcatagtc ttgaatgtcc gcaatcacag gtacataatc aatcccttgg aacttacgaa
      961 tcaattcatg ataaacaagg tagattgagt tttccccatg accgagcaag acaatgcgtt
     1021 caggattgaa gcgactaact tgacgacaga tttcagaacc gattgaacct ccagctcctg
     1081 tgactaagat ggtcttacct gtcagttctg cacccagacg cgattcgtca agacggattt
     1141 cctgacgacc caaaaggtcc gtaatatcaa ttttttggaa gccagtacct gcttggtgaa
     1201 ggccctgaac aacagtttca accttaggca tcttgtaaca tttgacaccc agcttattac
     1261 acatctgcaa gatacgctca tattctgacg gatccagcga cggaatcgca acgatgacac
     1321 gctcgatttg atggcgtttg gctaattcag gcagattgtc ataagagccc aaaacaggaa
     1381 taccaccaag tttttgaccc tttttcttag aatccttatc caaaataccg accagttcta
     1441 attcactggt tggatgttgg taactatcca taaaaagagc cccaccatca ccggcaccaa
     1501 tcaagaaggt ccgacggtgt tctccatcac cactaccttt tttgcgtctg gagtagatta
     1561 actgccaagt aatccgtggc aataaaatca agaaggtact caacaagata aagagaatga
     1621 tgaaacggat ggagaagagt ggcaagaagg cataacagat actatatgac aagacactgc
     1681 tagcagtcac accaaaaaag attttcatga aatccgtaat cttgctgtaa cgactaatgc
     1741 tcgcgttcaa cccccaaaaa ccaatcatca attgatagaa caggaaggcc aaactcgtat
     1801 agataatgta gtcaacaggt gctggattaa tcagcccata aaataaaata taagatacaa
     1861 tgatggaaac caccatactg aaaatatcaa atattcccca gaaaacctgc ttttgttgtt
     1921 tatttaaaat ttccaccaga tcaatcacat aatctgttag ttttttattc atagaaatct
     1981 actcctcctt aaaagagttt tactatattg ttattatagc atatttttgt ttatttggct
     2041 tattttatcc aaataaatta ttgttctctt gtactccttc ttccatttaa atcctctaat
     2101 taaacctaca atcgtcccaa agccataagc aaagtgaatg gaaaataaaa gaaagggcat
     2161 cacaattaga aatccatttt tatgttttaa taaagtcagc aaagtgagta gtgacaaaag
     2221 tagaaaatag gcacctaata gtaaagttat gaatacgaat gtgatcggta acaatgctag
     2281 actaaacaca agactcaaaa caaataaaca aggaacatag tgaaataatg ataaacactt
     2341 aaactgaaca tgacttgtca agccaatcca caaaccattt aaatactttt gatgcagcat
     2401 tttcttgaat gttggtcgaa tatactgata agatagaata cttgggctat agcggatttt
     2461 ataaccatat tctcgaattc tataatgaat atcattatct tcagttcggc caagttgctc
     2521 atttactaaa ccaaccttct ggaaaacctc tcgtttatac attccatgaa aaatagaaga
     2581 aacatatcta tcctcagaac tatttcgata attggcaatg ctactgccaa acatattttc
     2641 ctcaacaaga tgcaaggtct ctgcccattt tccttttcct tcgacaatcg tcggtctagg
     2701 ccccccacag acaaattcac cttgttgaat aatagccaca ttgttcatta caaaactctc
     2761 agtaactttt gaatgagcat caatttttaa aataaggtcc cctacagaat gtttaactcc
     2821 caggttaaaa ccactagctt gatttttctt aggattgtta tacaatctaa ttgagttaaa
     2881 ctctgtatct tcctttataa attgctgaat gatagctgtg gtcccatctg tggacatagc
     2941 atttataaat agaatttcaa tattctcttt aggataagtt tgatttttta agtcttcaat
     3001 tagaccaggc agatattttt cttcattgta tgcactgatt acaatggata caagaagact
     3061 ttcaacattt tgagtcacta ctactctcct gaatttttcc ttccaccatt ttatcataat
     3121 tttcaagact ttcccatttt tatcttgaaa gccagaaacc ttacttgaca ttatagtgaa
     3181 aaagccttaa aataagctgt tattaaaatc agctagaaga ggtattatat gaaaaagcaa
     3241 tcactctttt ttgttccagg tattatcctg attggtgttt ccttgcgaac tccttttact
     3301 gttttaccca ttattttggg aaatatttcg caaggtctgg aggtagaagt tagttcgctt
     3361 ggtgtcttga ccagcctgcc tctccttatg tttaccctct tttcaccatt ttctacccaa
     3421 ctggctcaga aaatcggctt ggagcatctc ttcacctaca gcctcttctt cttgaccatc
     3481 ggctcactta ttcgactaat caatctgccc ctactctatc taggaacctt gatggttggg
     3541 gcaagtgtcg cagtcatcaa tgtcctgctt cctagtctta tccaagccaa tcaaccaaag
     3601 aaaattggtt ttctgaccac cttatatgta acgtctatgg ggattgcaac ggctctggct
     3661 tcctatctag ctgtgcccat tacacaagcc agttcttgga aaggacttat ccttctcctc
     3721 acgttactct gtctagcaac ttttttggtc tggctcccaa atcaccgcta taatcataga
     3781 ctagctccac aaaccaaaca aaaaagtcaa ataaaggtca tgcgtaataa acaggtttgg
     3841 gcaattatta tcttttcagg ttttcaatcc ttgatctttt acaccgccat gacctggtta
     3901 cctaccatgt ctatccatgc aggtctatcc agtcacgaag ctggcttgct gacttctatc
     3961 ttatctctga ttagcattcc tttttcaatg accatcccaa gcctgacaac cagtttatct
     4021 actcgcaacc gtcagctcat gctcactctg gtttcactag ctggtgtggt cggcatttcc
     4081 atgctctttt tcccaatcaa taatttcatt tactggcttg ccatccatct cctcatcgga
     4141 accgcaacca gcgccctctt cccttatctc atggtcaact tttcactcaa gacaagcgcc
     4201 cctgaaaaga cagcccaatt gtccggccta tctcaaacag gaggctatat cctagcagcc
     4261 tttgggccaa ccctctttgg ttacagtttt gacctgttcc actcttgggt accatctgta
     4321 gctgccctct tgctcatcga tatcctgatg actgtggccc tctttacagt ggacagagcg
     4381 gataagatcc tttaaacttc tagttttagc tagaagtttt ttatatataa aaattttaca
     4441 catttctctt gacagggctt tcttttagat gtacaatgta tgtgtagaaa aattatatat
     4501 aaaaatctta cacattagaa aaggaggttt cccatgtact ttccaacatc ctctgccttg
     4561 attgaatttc tcatcttggc cgtactggag cagggtgatt cttatggtta tgagattagc
     4621 caaaccatta agctcatcgc taatatcaaa gaatccacac tctatcccat tctcaaaaaa
     4681 ttggaaggca atagctttct gacaacctat tctagagagt tccaaggtcg catgcgcaaa
     4741 tactactcct tgacaaacgg tggtatagag cagctcttga ccctaaaaga tgaatggaca
     4801 ctctatacag acaccatcaa tggcatcata gaagggagta tccgccatga caagaactga
     4861 atacctgact cagctagaac tctatctcaa gaaactacct gaagctgacc gtatcgaagc
     4921 catggactat ttcagagagc tctttgacga tgctggagtc gaaggagaag aagaactcat
     4981 cgctagtttg ggaactccca aagaagcggc ccacgaagtt ctatccaatc ttctcgataa
     5041 aaaaatcaat gaagcacccg ctcaaaaaaa taaccgacaa attttacata tcgccttgtt
     5101 agccctcctt gcagcaccta tcggcattcc tctgggaatc gccatcctcg tgaccctgtt
     5161 cgcaatcctt gtagccgctt tgactgtcat tctggctttc tttgcagttt ccatactggg
     5221 tatcatcggc ggattcctat ttttagttga aagtttcact gtcctcgccc aagccaaatc
     5281 agcctttatc ttgatttttg gttctggttt actggctatc ggtgcttctt cgctagtttt
     5341 acttggcatt tcctatgtaa ctcgcttctt cggtctactc attgttcgtc tggtacaatt
     5401 tgttcttaaa aaaggaaaga gaggtaacca gcatgcgtaa atggacaaaa ggatttctca
     5461 tctttggtgt ggtgactacc gttatcggct ttatcctgct ttttgtaggt atccaatctg
     5521 acgggattaa gagcctactt tccatgtcca aagaacctgt ctatgatagc cgtacggaaa
     5581 agctaacctt tggcaaggaa gtcgaaaacc tagaaattac tctccaccaa cacacgctca
     5641 ccatcacaga ctctttcgat gatcaaatcc acatttctta ccatccatct ctttctgctc
     5701 accatgatct tatcaccaat cagaacgata gaactctgag tctcactgat aagaaactgt
     5761 ctgaaactcc gtttctctct tctggaattg gtgggattct tcatatcgca agtagctact
     5821 ctagtcgttt tgaagaagtt attctccgac taccaaaagg gagaactcta aaagggatca
     5881 acatctcagc caatcgcgga caaaccacca tcataaatgc tagccttgaa aatgcgaccc
     5941 tcaatacaaa cagctatatc ctccgaattg aaggaagtcg tatcaaaaac agtaaactca
     6001 caacacccaa tatcgttaat atctttgata cagttcttac agatagtcag ctagagtcaa
     6061 cagagaatca cttccacgct gaaaatatcc aagtccatgg taaggttgaa ctgactgcca
     6121 aagattatct cagaatcatc ctagaccaga aagaaagcca acgaattaac tgggacatct
     6181 caagcaacta tggttctatc ttccaattca caagagaaaa gcctgaatca agaggtacgg
     6241 aattaagcaa cccttacaaa actgaaaaaa ccgatgtcaa ggatcaactc attgcgagat
     6301 ctgatgataa tattgatcta atatccacac caagcagacg ttgacaaaaa cgcttacatc
     6361 tgctactatg gaagcatatt tatctaacta aaaaggaggt tctaccatga aacaagaatg
     6421 gtttgaaagt aatgattttg taaaaacaac aagcaagaac aagcctgaag agcaagctca
     6481 agaggttgca gacaaggctg aagaaacgat agccgatctc gatacaccaa ttgaaaaaaa
     6541 tactcaagta gaggaggaag tctctcaagc tgaagtcgaa ttggaaagcc agcaagaaga
     6601 gaaaattgaa actcctgaag tcggtgaagc gagaacagaa atagaagaaa agaaggcatc
     6661 taattctact gaagaagagc cagacctttc taaagaaaca gaaaaagtca ctatagctga
     6721 agagagccaa gaagctcttc ctcagcaaaa agcaaccacg aaagagccac ttcttatcag
     6781 taaatcttta gaaagtcctt atatccccga ccaagctcca aaatctaggg ataaatggaa
     6841 agagcaagtg cttgattttt ggtcttggct agtggaagcg atcaaatctc ctacaagtaa
     6901 gttggaaaca agtatcacac acagttacac agcctttctc ttgctcattc tgttttctgc
     6961 atcttccttt ttctttagta tctatcacat caaacatgct tactatggac atatagcaag
     7021 cattaacagt cgcttccctg agcagctagc tcctttaact cttttttcta tcatctctat
     7081 cctagtagcg acaacactct tcttttcatt cctcttgggt agtttcgttg tgagacgatt
     7141 tatccaccag gaaaaggact ggacgctaga caaggttctc caacaatata gtcaactctt
     7201 ggcaattcca atcttcctca ctgctattgc tagtttcttt gctttctttg atagcctacg
     7261 atttacagcc ctcttgtgtg tgattagcat tggaatcatt ctgcttgcca gtctccatat
     7321 cattacaaga ccaagtcaag caagtgaaac cgactccttc tatcaattat tcttgtctgt
     7381 ccttgtgaac ggagttatta tcctcctctt ctttgtagct gaagtggcac tgattggaga
     7441 ttatcttcgt atcttggcct ttctttaaaa ttcaatcctg tcatccttgg caggattttt
     7501 tctatgtcaa aaaagcaagt cgattgacct gcttctgctt tacttttctt gtgctaatgt
     7561 tttaaaatct tgtcctagga tgggttgtat ttctatttga ttggcgtcta gttggtggta
     7621 aaaagatggg ggtaatacct ctaagaattt tgcatagtcc aagcgagcta tggattcata
     7681 gtcttctggt ttagagccgt ctcctgtgat ttgaaccaag taaatctccc actggacttc
     7741 cttatccacc aattgctcaa tataggctgc aggaacaaac ggttctctcg gtaaaactgt
     7801 cttgactcct tgagctaaat ggtaaacgcc atgcactttt ccttctccat cctgatagaa
     7861 ggaaactatc gcaaagtagg catctgtctc ttgaaccgca cgcacacgcg cttcaaactg
     7921 agccaagcca tctgcctcta aaaagctttt caagttctca cgactaaaga aaataggatt
     7981 aaaaattcct tggcaaatcg taaaacgagc tacagggtct gctagatagg cttgaatact
     8041 tgcttggaaa taagcttcaa aatcaaaacc atctagccct tcaatatcag tccctgtata
     8101 agcaagcaaa gcatctaaaa atgacttgat aatctgccag tctgtctttg ttagtaggtc
     8161 aggaagatcg acacggtaag ccttttgacc atcagcataa ctgaccttaa agagaaattg
     8221 tgattgcccc actatcgcac actcaatata ctcgagacga ttaagaggct gacgaagata
     8281 gactacatca tagctatgtg actccaaacc gtctagcaag gccaagatcg acttggcatt
     8341 caaaatctct tgttctccta aaatgctctg tttatttgga ataaaaaatg tttttgccat
     8401 aactggactc ctttgaaatc gtttacatac agtatacctt attttcctga aagatacaaa
     8461 aacaaacttt agatttttga gtacaaagca tagaaaaaca gcccctgagg actgtttgat
     8521 cttatacagt agctgcctga tccaagcttt caccgatagc ggctaggcgc tcaatcactt
     8581 cagcttgtgt caattcattt tttgaaacat agcggttacg tgggtgaaca cggcactcgt
     8641 gtgagcatcc acgaaggtac ttgtcttcat tttcttctga tgtcaagata cgacggttac
     8701 agaagggatt tccacagtta acataacgtt cacatggtgt tccatcaaac cagtctttcc
     8761 ctacgatggt tgggttgaca tggttgacat caacggcaat acgctcgtca aagacgtaca
     8821 ttttcccatc ccaaagctca ccttgaactt ctgggtcttt accgtaagtt gcgattcctc
     8881 cgtgcaattg gccgacatct ttgtagcctt cacggaccat ccagcctgag aatttctcac
     8941 agcgaacgcc acctgtacag taaaccacga cacgcttgtc catgaatttt tccttgttat
     9001 cacggaccca ttgtggtaac tcacggaagt tgcgaatatc tgggcgaata gccccacgga
     9061 aatgtcctag gtcgtactca taatcgttac gtgtgtcaag gacaacggta tctttatcaa
     9121 gaagcgcttc tttgaactct tttggagaca agtaagcacc tgttgtttca agtgggttga
     9181 tgtcattgtc aaagtcgttg tcttccaaac caaggtggac aatttctttc ttgtagcgaa
     9241 caaacatctt cttgaaggct tgttcatttt cttcgtcaat cttgaaccag agatcttcca
     9301 tacctgggag gctgtgaacg tagtccatgt atttttgagt tgtttcatag tcacctgaaa
     9361 ctgttccgtt aattccctcg tcagcgacta ggatacggcc tttaaggccg attgatttac
     9421 agaaagccaa gtggtctgca gcaaattgct ctgcattttc aattggagta taaaggtagt
     9481 aaagtaagac acgaatatct tttgccataa gatttgttct cttttctatt cttaaatttt
     9541 ctaaattttt tatttatcca tactagtata cctgcttgag aaaacgaatg caatttattt
     9601 gactggaaat tgtagaggat tctcgaaatt tcctgaatgg ttaaaataag gacaagagaa
     9661 aacagggata tctatatcct tgtgccaaaa aaaccactgc cctccccaga ccaacctgag
     9721 gaaagcagtg attcttattt taggagttag gaatgaatac acgaaatcaa tttagctgat
     9781 tattttttgt ttttcaagaa ttcatcgtat tgtttttgca tttcgttcaa tactttttcg
     9841 taggcacctt cagatttcaa tttttccatc aattctggaa tcgctttatc tgggtctaca
     9901 gtaccagtgt tgatagctgt atcaaattgt tgcattgtgt tagcaatagc tgagatttca
     9961 gatttcacat tgtcagtatt gaagataaat ccaagcgctg gagattcttt agcttctgcc
    10021 aattctttct tagaattttc gatttgttgg tctgtaacgt tttcgttgat gtaaaggatc
    10081 cagttgttac cagtgttcca tccacccatg tgagtgtttc ctttgtagcc atcaagaacg
    10141 cgaacacggt tttctttacc ttcaattttt tcccagttct tgccttctgg accgtaaaca
    10201 agaccgttca agagttctgg attcgtattc aagaggttca agatttccat tgatttttct
    10261 ttgttcttag agttgtttga gatgacaaag ttagcaactt gtgttgtttg gtttttcttg
    10321 atgaagttag taattggttt gatttggata tctttgttgg caacacgtga aagcaagctg
    10381 ttaccgtagt cagctggtcc tactgtttct tcacgaacga accaagtatc ttgttgaagg
    10441 tcaaaggaag tatcgcttgt tgcgacgtct tttggaatgt agccagcttc atagaatttg
    10501 tgaagagtct tcaagtgttc tttgaaacga ggcacttcgt aacggtttac aactttagta
    10561 gtatcgcctt caaggtcgat aacgaatgga agaccgtttg ctactgggta gtcaaagtta
    10621 tcagatggga tgaaaacttt accaatagca aatggtacta cgtctggagc tttttcttta
    10681 atttgtttca agactggctc aagagtttcg taagaagtaa cacctgaaat atcgatacca
    10741 tatttagcaa ggagagttcc gttgaaggca aagttttgag atgatgcaac gttggctgca
    10801 actggaacag cgtaaatctt accatttaca gtattaccct tgatgtaagc tgggtcaagt
    10861 gccttgtaaa ggtctttacc ttcttttttg tacaattctg tcaagtcagc gtaagcacct
    10921 ttttgagcat ttacaatata gttatctgca aaggcaatat catagttttc accagatgat
    10981 gtgataactg acattttctt accatagtca ccccagccaa ggtattggat atccaattta
    11041 gcaccaactt tttcttcgat gattttgttg gcatttgcta acaattcatc caagttatct
    11101 ggtttgtcac cgatttggta cattttgata acaggtttgt cacctgaatc agcagctttt
    11161 ttgctgttac ctgtcaaatt tccacaagca gcaagacctg cagccaaagc gactacacta
    11221 gcagatgcaa aagcatattt tttccagttt ttcatgataa aaactccttt ttttattttt
    11281 aaacttataa acaatgtaat gatcttatac tcaatgaaaa tcaaagagca aactagaaaa
    11341 ctagccgcag gctgctcaaa gcactgcttt gaggttgtag ataagactga cgaagtcagt
    11401 tacatatatc tacggcaagg cgacgttgac gcggtttgaa tttgattttc gaagagtatt
    11461 aacttcatac aagggaagtt gggaactgag aaatgttctt tttcaataag cactattctt
    11521 tcacaccacc gatagtcaaa ccttttacaa agtagcgttg gaagaatgga tataaaatcg
    11581 cgattggaag ggttgcaacc acaaccatgg ccatacgacc tgtttctttc ggtagagcaa
    11641 ctcccagttg accagtcaag ccgaccgctt tggcaatgta gtccatattt tgttggattt
    11701 gcatgagcaa atattgcaat ggatacaagt tatcactctt gatgtaaaga agggcgttga
    11761 accagtcatt ccagaaacca agagctgtca aaagcgtgat ggttgcgata cctggtagtg
    11821 acaatggcaa acagatttgg aagaaaatcc gggcctcact ggcaccatcg atacgagccg
    11881 attcgagaat ggcttctgga atggtcttct tgaagaagga acgcatcaag atgatattga
    11941 atggtgagag aagcattgga acaatcaagg cccaaacagt gtcaccaagc tgaagtacac
    12001 gggtcaccat gatataacct ggtaccaaac cagcgttgaa caacatactg agaaggacga
    12061 agatggtaaa aaatctgcga tacttaaagg ttgtccgtga aatagcgtag gcataggttg
    12121 ttgtgataaa gacatttgtc aatgtcccaa ctacggttac aaagacagag atgaagaggg
    12181 cttgtaggat tttatcctta aactgtgcca aaaactcaaa accgtctaag ccaaattggg
    12241 atgggaagaa gctatagccg tattggagga ggcttttctc gtctgtcact gaaataatga
    12301 taacgaatac aaaaggtagg atacaagaga gggcaatcaa acccgaaatg atactgaaga
    12361 agatatctgc tttcttactg aaggagtgaa tgccgacatt atcaattttt tcttttttaa
    12421 ttttcttttt tgccatattc tcctcctttc tagaacaaag ctgagtttgg atcgactcgt
    12481 cttgcaagca agtttgatag gataaccaga atcaaaccaa caacggattg gtaaagaccg
    12541 gctgctgcag ccataccaat atctgctgtc tgagtcaaac cattaaagac atatacgtcc
    12601 aaaacgttgg ttacattgta aagctgacca gcattgtgtg ggatttgata gaagagaccg
    12661 aagtctgcgc ggaagatatt tccgactgca aggatggtca atacagttac aagcggagtc
    12721 aactgaggaa tggttacgtt gcgaatacgt tgccacttgc tagctccgtc cactgtcgct
    12781 gcttcgtagt aggttggatc aattcccatg atcgtcgcat agtacatgac actgctatat
    12841 ccaaagcctt tccaaatacc taggaaaagt aggagatagg gccagatgcc caggtcagcg
    12901 tagaaattga cttctttgag accaagactt tccaatagat gattgaacac ccctttatca
    12961 atatttagga aggcatctgt aaagaaactg atgataaccc aagacaagaa gtaagggaac
    13021 aacatagaag tttggaaaat cttcaccatt ctcttagaac ggagctcgct gaggataatg
    13081 gcaatcccta cagatacaac taaacctaga aagataaagc caagattgta gaggacagta
    13141 tttcgtgtga taataaaggc gtctcttgaa ctaaataaga atctaaaatt atcgagtccg
    13201 acccatttac tatttatgat actatctatg aaaccattac tggtcatgtg gtagtctttg
    13261 aaggcaacca cgttcccaaa tactggaatg taaaagaata gaatcaacca gagtgcccct
    13321 ggcaaaacca tcaagagaaa gatccagttg tctctcaatg tttttgaaaa ctttttcata
    13381 atttcctccc tttttatttt gatatccatc taaaaattct tttttagact tttgataacg
    13441 attacattat tagtatactc ctatttgcag gttaggttaa actcctaatt atagaaaaaa
    13501 ctccacaaat tatgtagcag atttaaaact ttatcaccac tatcaaacaa atgtcctaaa
    13561 tcaattgttt attttatctc tattagccca gtgatggcgt cactctgtta taagcatcca
    13621 acaacggggt atactgaaaa atctccagac tagggaactc agcgatagtt cctaatctgg
    13681 agatttttaa tatgttatta ggcgtttgct ttcaacttag caataacctc tttaagatta
    13741 tcaatcaact ctgctgcagt atgctcagag cctttttcat ctgccaagaa caaaactgct
    13801 ttttgaagtt cttcttgaga gttttcaagg acatccttat ctactgtttc aaggtttgag
    13861 tctttaagaa gtttacttaa ttccttggct aatttcttga gtttgatttg cagactcatc
    13921 ttctcctgct gtttctttgc ccgctgtttg tcctccatcc ttagttgctg actggctttc
    13981 cttaatggac tctagggaag caatggcatc tttgactgtt tgcaagatat cacgtaaacc
    14041 ttgctctatc aaactatcat ctgcaaaagc tttcttagcc tctgccaaaa ccagaggtgc
    14101 tgaatctgtg gtaggattcg atacacctgt caatgatctc aaaagatttt ctaaggtttg
    14161 agtctgctta ctaatactag actcaaatca aaaagcatta tataacagtg atatgaaatc
    14221 aactaaagaa gaaatccaaa ccatcaaaac acttttaaaa gactctcata cagctaaata
    14281 tcataaacgc cttcaaatcg ttctatagta aaatgaaaca agaacaggac aaatcgatca
    14341 ggacagtcaa atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca
    14401 atccattata tttcgtctga tgggcaaatc ttataaagag attatagaac ttttatagta
    14461 gtttgaaata agatgtgaac aactctatca ggaaagtcaa attaatttat agaaatattt
    14521 tagcagccaa ggtgtactgt tatagattca atacactata cttggtggtt tagctctcct
    14581 gttttctctt ttagctttaa ccagccataa atggtattac gtgagatttg aaaaacgtgt
    14641 gatgcttctg ttatactacc tgttcgctca caataagaga gaactttttt acgaaaatct
    14701 attgaatatg ccataaaaga ttataccaca ttgtgtacta tttttggttc attttactat
    14761 atcactttgg actatatcgg tctagttatg tctaaacgat tatagctgga tactaagaga
    14821 aatcaaaaaa gcactaaggg agaacgtccc aaagtgctta atatcaaggc ctcaaagcct
    14881 atcttattta ataaaatatt acaacatttt gttgtagaat tcaacgacaa gtgcttcgtt
    14941 gatttctggg ttgatttcgt cgcgttctgg caagcgagtc aatgaacctt ccaacttttc
    15001 agcgtcgaat gatacgaatg ctggacgtcc aagagtagct tctactgctt caaggattgc
    15061 tggaactttc aatgattttt cacgaactga gatcacttga cctggagtta cgcggtatga
    15121 tgggatatca acgcgtttcc cgtcaacaag gatgtgaccg tggtttacga attgacgagc
    15181 ttgacgacga gtagtcgcga gaccaagacg gtaaacaacg ttatccaaac gacgttccaa
    15241 aagaagcata aagttgaaac ctaggattcc gcctttgatt tttgtagctt gtacgaacaa
    15301 gttacggaat tgtttttcac ctacaccgta agtgaaacga agtttttgtt tttcagccaa
    15361 ttgcaaaccg tattctgaca atttagaacg gttgtttggt ccgtgttgtc ctggtacgta
    15421 gttacgacgt gccaattctt tacctgtacc tgtaagtgaa aggccaaggc gacgagcttg
    15481 tttccaagat ggtcctgtat aacgtgacat atgaatgtcc tcctgatata aataatattt
    15541 cggtggaaat agtcacttag aaagccctga ttcgtgcaga tgcccttcgc ctaaacagcc
    15601 aaggttactt gtcataagac acctgttgac gagcttcatg ctttcctgct gatatttcac
    15661 acaaaatcta ttctaccatg aatagctgga tttgtaaagg ggttttaggc tttattttca
    15721 ctaccagaga ggttgagaac gagggtaaag gtacttccta gaccgtactg gctgctgact
    15781 gtgatttccc cacccaattg atgggccaat tcacgcgcaa tcgcaagtcc taatccatga
    15841 ccacctgtct tcatgttacg cgaagtttcg acacgataaa gacgtttgaa aatattttcc
    15901 aaatcctctg gggcaatacc ctgcccttca tcggtcacac tgattgaaag ctggtccttc
    15961 tccagcttag ccaccacttc cagcttggtt cctggagcag aatatttaaa agcgttatcg
    16021 accagattca ccaagatacg agaaagctta gcataatctc cctcaatccg ggcagactct
    16081 gggattacct gcaagtggac atctcttctc tcctgctcaa tcaaaaactg aaattcactc
    16141 atgcactcaa ttaagagctt gtccagaaaa atactgtctt tactggtagt ttccacctga
    16201 tttctagctg tgtttagggt caaaaaattc aactcctcaa ccagtttatt gagcctctcc
    16261 gtctggcgtc caatggttgc tagataatga gcttgctccg actccttgat aatcccatcc
    16321 aaaatccctt ctaccgtcgc ttgaatcgaa gtgatagggg tcttaatatc atgcgacaac
    16381 tgggcaatca tcaagccctt ttctcgttcg ctttcttcca aggaatcaaa gcttacctgc
    16441 aaatcatggg acatctcatt aaaagtttgc cctaattgct gaaattctac aggaccttga
    16501 acctccaaat ttgaaggaaa atccttggcc gctacccgct tggcatgctc cttgagtttg
    16561 cccaacgacg taaagactgg caataggaga aagagactaa tcccagcacc gacaaggctg
    16621 gcaacgatgg tcatcccaag caaaaagtaa atctcgcctt tcgcaatcag cattttttga
    16681 acagcccaaa aaacaaccaa aatggttaag agggttgaaa taatatatcc aaccaaaata
    16741 taacttttta gtttcatgtt tgtcctctcg gtttctctat cttatatccc aacccccaaa
    16801 ctgtcttaat agtgggcgtt tggtcactac tatattttgc cagctcctgt cgaagagcat
    16861 ggatatgcac attcaaggta ttggtgtcat ccacgtagtc ttctttccag atcttttcat
    16921 agaggtctgt cttggagaaa actcgctctg gattgctagc taaaatccac agcaattcaa
    16981 atgatttaac agttaaatcc agcatttctt ctcctatttg aacttcatga ctactatgat
    17041 tcatttttag attgccaagg gaaatcagct ctgtttcgcc cccacgatga aggcggcgca
    17101 aaatattgtg gacacgcaaa actagctcac gtgggctaaa aggcttagca ataaaatcat
    17161 ctgctcccaa gctcaggccg taaatcttgt cctgttcact ggtcttagca gtaataaata
    17221 ggaaaggctg ctctggtgat aagtattgaa cctcactgat taaatcataa ccatccatcc
    17281 gaggcatcat gacatctgtg ataatcaaat caatcggttt tttcttgaac agctctagcg
    17341 cttccagtcc atcatgggct accaagacct gataacctgc ctgaattaag tatctctgat
    17401 gaatatctgt gatttctacc tcgtcgtcaa cgagtaaaat tgtctttccc atctgtctct
    17461 cctttgataa aaacagtgct atactgcttt aagtataaca ctatttttat tgttttacga
    17521 tgattttaat ctgctattga aagaaagtcc tgattgctga ttgagttgtt aaactaatct
    17581 tagtcagccc actatccatc atttatttcc ttagctgatt agttttcttc ttttttgttt
    17641 ttcaaaccta gaccaccgag taaacctgca agcgcaagcc caaggaaacc aatacttgcc
    17701 attgatgttt gagtctcacc agtatttggt agcatagctt tatcctctga catcatcgta
    17761 tcagacatct tgttagcaga agcagccatg ttttcacctg ccatcgtgtt ggtagaactt
    17821 gtcatggtgt cagcaggcat gctatctgta gtacctgtag catgattgtg attcatcgga
    17881 gtcacgccag aaccagagtt agaaggtgat aatgaaccat ttgctgtgtc tgatgtttct
    17941 ttaacattta t
//
LOCUS       DAVLZS010000038        17814 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLZS010000038 DAVLZS010000000
VERSION     DAVLZS010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.038"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..424
                     /locus_tag="VYO88_001454"
     CDS             <1..424
                     /locus_tag="VYO88_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719536.1"
                     /translation="FLFIVSLFFYTSEIIMFIWILSTVLYVADKIRIVKEKIKYDKII
                     NATQEKYREEKKKLLSTLRKEYYSIPTEFRTYNHISGIQYFLNADIASNLQQAIHYYS
                     NEYNSKRMQDQIYSLHHSNTILQDRIKELELERELEKY"
     gene            445..837
                     /locus_tag="VYO88_001455"
     CDS             445..837
                     /locus_tag="VYO88_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719537.1"
                     /translation="MTKFNLQSNQIYSELSKFEIEEILYNATKQLNGSVERQSSEEIS
                     YSGQGNFFDYMKHPGLSRYTCWQVLVTISDLGDKRKVELTAVGESPISYLLNNFLSFI
                     TFYTLFQRHRNLNFGISKEKAKYLSNLL"
     gene            complement(1023..2585)
                     /gene="guaA"
                     /locus_tag="VYO88_001456"
     CDS             complement(1023..2585)
                     /gene="guaA"
                     /locus_tag="VYO88_001456"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1719538.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2727..3425
                     /locus_tag="VYO88_001457"
     CDS             2727..3425
                     /locus_tag="VYO88_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1719539.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3468..4364)
                     /locus_tag="VYO88_001458"
     CDS             complement(3468..4364)
                     /locus_tag="VYO88_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1719540.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4373..5308)
                     /locus_tag="VYO88_001459"
     CDS             complement(4373..5308)
                     /locus_tag="VYO88_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1719541.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5305..6030)
                     /locus_tag="VYO88_001460"
     CDS             complement(5305..6030)
                     /locus_tag="VYO88_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV1719542.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(6114..6749)
                     /locus_tag="VYO88_001461"
     CDS             complement(6114..6749)
                     /locus_tag="VYO88_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1719543.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(6751..7578)
                     /locus_tag="VYO88_001462"
     CDS             complement(6751..7578)
                     /locus_tag="VYO88_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1719544.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7600..7935)
                     /locus_tag="VYO88_001463"
     CDS             complement(7600..7935)
                     /locus_tag="VYO88_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV1719545.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYVLEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7936..8652)
                     /locus_tag="VYO88_001464"
     CDS             complement(7936..8652)
                     /locus_tag="VYO88_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV1719546.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEEDITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            9175..9786
                     /locus_tag="VYO88_001465"
     CDS             9175..9786
                     /locus_tag="VYO88_001465"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1719547.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9831..10559
                     /gene="rlmB"
                     /locus_tag="VYO88_001466"
     CDS             9831..10559
                     /gene="rlmB"
                     /locus_tag="VYO88_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1719548.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(10598..11509)
                     /gene="trxB"
                     /locus_tag="VYO88_001467"
     CDS             complement(10598..11509)
                     /gene="trxB"
                     /locus_tag="VYO88_001467"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1719549.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYEART
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11575..11799)
                     /locus_tag="VYO88_001468"
     CDS             complement(11575..11799)
                     /locus_tag="VYO88_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1719550.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11877..12620)
                     /locus_tag="VYO88_001469"
     CDS             complement(11877..12620)
                     /locus_tag="VYO88_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1719551.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12620..13420)
                     /locus_tag="VYO88_001470"
     CDS             complement(12620..13420)
                     /locus_tag="VYO88_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1719552.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13578..13934)
                     /locus_tag="VYO88_001471"
     CDS             complement(13578..13934)
                     /locus_tag="VYO88_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1719553.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13928..14458)
                     /locus_tag="VYO88_001472"
     CDS             complement(13928..14458)
                     /locus_tag="VYO88_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1719554.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGADKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(14458..14952)
                     /locus_tag="VYO88_001473"
     CDS             complement(14458..14952)
                     /locus_tag="VYO88_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719555.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            15087..15533
                     /locus_tag="VYO88_001474"
     CDS             15087..15533
                     /locus_tag="VYO88_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1719556.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTIKLYHQTLDLIDHTQEEVIQ"
     gene            15530..16177
                     /locus_tag="VYO88_001475"
     CDS             15530..16177
                     /locus_tag="VYO88_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1719557.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(16198..16779)
                     /gene="pdxT"
                     /locus_tag="VYO88_001476"
     CDS             complement(16198..16779)
                     /gene="pdxT"
                     /locus_tag="VYO88_001476"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1719558.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16780..17655)
                     /gene="pdxS"
                     /locus_tag="VYO88_001477"
     CDS             complement(16780..17655)
                     /gene="pdxS"
                     /locus_tag="VYO88_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1719559.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
BASE COUNT         5410 a         4016 c         3137 g         5251 t
ORIGIN      
        1 tttcttgttc attgtatcac tattttttta cacttcagaa attatcatgt tcatttggat
       61 tttatctaca gtactatatg tagcagataa aatcagaatt gttaaagaaa aaataaaata
      121 cgataaaata ataaatgcga ctcaagaaaa atatagggaa gaaaagaaaa aattattatc
      181 tactttgcga aaagagtact actccattcc aactgaattt agaacatata atcatatttc
      241 aggtatacaa tattttttaa acgctgatat tgcatcaaat ttgcaacaag ctattcacta
      301 ttattcaaat gaatacaatt ctaaaagaat gcaagaccaa atttatagct tacatcattc
      361 aaacacaata ttacaagata gaattaagga gctcgaatta gaaagagagc tggaaaaata
      421 ctaatcaaaa aggagaatac tacaatgaca aaatttaatt tacaatcaaa tcaaatttat
      481 agtgaattaa gtaagtttga gatagaagaa atactgtata atgctacaaa acaattgaac
      541 ggtagtgttg aacggcaaag ttctgaagaa atttcatact ctggacaggg aaattttttt
      601 gattacatga agcacccagg tttaagtaga tatacatgtt ggcaagtctt agttactata
      661 tcagatttag gggataaacg aaaagttgag ctaactgcag tcggagaaag tccgattagt
      721 tacctactaa ataattttct atcattcatt actttttata ccttattcca acgtcatcgt
      781 aatcttaatt ttggcatatc aaaagaaaag gctaaatacc tttctaattt gttgtagaag
      841 ataatttata tacaaaaaac tctcttagta catattcaca ctaagagagt tttttgtaat
      901 ctatttgcca agtttggcgg gaaaattggc ggggtaactt ttctaaaaag ataaatttat
      961 accattctaa cttctataaa cccgatagaa tcggtgtaaa acattcattt ttactttcta
     1021 tattattccc actcaactgt tgcaggtggt ttacttgtaa tatcgtagac gatacggtta
     1081 acatgatcca cttcatttac gatacgtact gagatttttt gaagtacttc ccatggaatt
     1141 ttggcaaaat cagcagtcat accatcgata gaagtgatag cacggattgc aatcgtgtag
     1201 tcatacgtac gaccgtcacc cataacaccg actgaacgaa cgcctgtgtt aacagtgaag
     1261 tattgccaaa tatcgcggtc aagtccagct ttagcgattt cttcacgaag aatagcgtct
     1321 gattcacgaa cggtttcaag tttctcttca gtgatttcac ccatgacacg gatagcaagt
     1381 cctggtcctg ggaatggttg gcgccatacg atatggtctg gcataccaag ctctgtacca
     1441 agagcacgaa cttcatcctt gtaaagagta ttgagtggtt caatcaattc aaactgcata
     1501 tcttctggaa gaccacccac gttgtggtgt gacttgatag tttgagctgt atccgtacca
     1561 gactcgataa catctgtata taaagtacct tgagcaagga atttcacatc tttgagcttg
     1621 cttgcttcgt catcgaatac atagacaaac tcgttaccga tgattttacg tttttgttca
     1681 ggatcagaaa cgccagcaag tttgtcaagg aaacgtttag cagcgtctgc tttgacgata
     1741 ttcaaaccaa acttaccacc gagcatgtcc ataacttgat cagcttcgcc tttacgaaga
     1801 agaccgtggt ctacgaagat acagatcaat tgatcgccaa tcgctttttg gagaagaacc
     1861 ccaacgacag atgagtcaac accacctgat agaccaagaa ggacacgttt atcaccgacg
     1921 gtttcacgaa tttttttgat ctgcatgtca atgaaattat ccattgacca gtcaccttta
     1981 gccttacaaa tgttaagggc aaagttacga aggatatcat ttccgtatac agaatgacga
     2041 acttctgggt ggaattggat accgtaaatg tgtttatctg ggttttcgat ggctgcgtat
     2101 gggcagtcag ctgatgtacc tgtacgaaca aagtcagcag gaatctcagt aaccgcatca
     2161 ccatggctca tcaaaacagt ctgttcatca ggtgttgatt caaaaagcgc tgatggtgtg
     2221 tgagttaggg ttgattgacc gtattcacga tttccagcat cacctgcagg aacaactttt
     2281 cctccaagtt tatgggtcaa taactgcata ccataacaga ttcccaaaat tggaattccg
     2341 agttcgaaga tttctgggtc aatatcaaat gaaccatctt catatacaga atttggacca
     2401 cctgatagaa taattcctac aggattgact tcacgaactt cagcagctga aattttatgg
     2461 ctttttagtt ctgaaaaaac accaatctca cggatacggc gtgaaatcag ctggttgtac
     2521 tggctaccat agtccaatac gatgattttt tctacatctt gcaaatcagt tgaaatgttg
     2581 ctcatctttt tcctttctca aaagaaatat cttttctcaa tattctatca caaataaggg
     2641 cgaattacca actaaacaag gcgaagtttg actttttcta gtttattggg gtacaataga
     2701 gaaaagatag aaatgaagtg aaaaatatgc tacctgctta tatgaaaatc catgatcaga
     2761 taaaaaagga tattgacgag caccgttggg ctattggtga gaggcttccc agtgaaagag
     2821 atttagctga gcagtttgcg gtcagtcgca tgaccctccg ccaagccgta tctctattag
     2881 tcgaagaagg cgtcttagag cgccgtgtag gaagcggcac ctttgtttcc agtactcgag
     2941 tacaagaaaa gatgcgaggg acaaccagtt ttactgaaat tgtcaaatcc caaggtaaag
     3001 ttccctctag ccagctcatt tcctacaaaa aaaccattcc caatgagcaa gaagttgcca
     3061 agctaggaat ttttccaacg gacaatatta tccgaatgga gcgggtccgc tatgccgacc
     3121 aagttcccct agtttatgaa gttgcttcta ttcctgaaaa attcattaag gactttaaaa
     3181 aagaagaaat caccagtcat ttcttccaaa ccttgcaaaa acatggctat cgtatcggta
     3241 aatcccaaca gaccatctat gctcgccttg ctaaagaaaa gattgcccac tatttggaag
     3301 ttgaaaaagg acatgctatt cttggattga cccagatttc ctacctagaa gatggtactg
     3361 cttttgaata cgtaaaaagt caatatgtag gcgaacgctt tgaattttat cttgaaaata
     3421 attagattac cacgcaaaaa ctctctgtca cggacaaaga gtctttttta tttttctaag
     3481 aataaatctt tcaaagaaat caaagttaca gcaaacaata tcattgccat accaagaaaa
     3541 tcaatgggat aaaattgttc attcattatt aagaaggcaa agaaaatcgc cgatattggc
     3601 tcaattgaag ccaacaagct tgacttgacc ggtcctatca gactggctcc tttaaggaaa
     3661 gctgtatagg caaagacagt cccgataagg ataatgcctg caaacgcaag gagaaaatca
     3721 agactagtcg ggatatcggc ctgtagaacc cctgtaaaag gaagggcgac caaacctgct
     3781 atgaccattc ccacaccaat gaccaagctg ctcccccact ttttaatcaa ggctatgggt
     3841 aaaatgatat acagagcata agtcaaggca gaaaagagac cccagaacag accagcaggt
     3901 gtcatggata actggtccaa ctgcccatgt gttgcgatca ggaaggttcc tccgatggcg
     3961 aatatgatgg aaactatctc tcccagtgtc ggtgccaccc tatccttgat acagctataa
     4021 attaaaattc cgacaggaca aacatactga agcaccgtcg ctgttcccgc attggtctcc
     4081 tgaatagcag acagataggc gaattggttg agaaaaagac caatcagagc aaaaataaga
     4141 agagacagca aactctttct atcctttaaa aagaccagta ttttatcctt tgcagtagca
     4201 taagccaaga gcatgagaat tccaccagcg attaaaagac gcaagttagt caagaccaga
     4261 gccgaaattc cgtgtgccat taggtattgg ccactcgttc ctgacaaccc ccaagcaata
     4321 ccagccacaa ctgttagtaa agtccctttt aaactatttg acatgtctct ccttactctt
     4381 ctttgcgaat caagttcatc acttgattgc ggtctaatat ccattgagct ctctcgtcct
     4441 tttcataggt acgattcgat aggaaaatag tggcttcttg cttctgacga ttccacatga
     4501 taaaggtacc tgtatagccc gtatggtcta gccaatctcc ttccaaattc catgctaaag
     4561 aacgttcctt gtcatccaaa ggagaaaaat tttgatttaa gtctcttgca aaatcatctg
     4621 ctaaatagtg ttctaaaaag atttgtaaat cctttatagt cgaaaataaa ccagcactcc
     4681 cagcatgtct acccaggaga cgagccttgg gatcatgcac tatgcctgcc tctacacctc
     4741 taactgttgg aacagcaagc tcaactggcc caaacttggt ttccgtcatt ccccaaggtt
     4801 tccagacttg atcctttaaa atcacatcca aatcttgatt aaaaattctt tccaaaataa
     4861 agcccaacag caaaaaatgg acatccgaat aaagaaaggc tggctgactt cgtctgttga
     4921 gatgaaacat cgcttccttt aattcagggg ctgttaaaag atcacgatta ggaataaaag
     4981 gatcaaggtc tgttgcatga gtcaagagct ggcgaatagt gatgtctgga taatcactct
     5041 caggtaaaaa atctattacc agtctatcaa tatctaattg acctatttcc cacaagaagg
     5101 tacaaactgt gccaacccca acaaccttgc tgacactagc taggtcataa actagtcctg
     5161 cctcagtctg caagccatgc tctgggtcac tctggcctaa atagaactct gtccattgat
     5221 tgtccttaaa atacgcaaaa gaggctccgg gataaatccc tgcctcgatt tgttcttcta
     5281 tttttttaat aatcttggtc cacttcatac ttcttcaaac cacaattcaa cattatttct
     5341 atctttacca aggaagaatt tttcagactt aggaataaaa tattcagtag actcaaactt
     5401 ctggcgaaga cttgctatgt ctaattcatt gaccaagaac ttgagcatag ataagtccca
     5461 ggtaaccgta ttgtccacag tcaaatcctg cccctgagct ggaataaaat caagggatgc
     5521 cccaatttca gatgattcca agaaactttc gatatcagtt gggagatgta attccataga
     5581 aatctcaaat ttacttaaag aaattgatgc caaatctgtt tgaaattcag gcttttctcc
     5641 tacttctact agacttgcta tgtcatcttc cgcatgaatc aaaatcaaat catcttctgg
     5701 tgagaaaatt tcaaaagcgt agccattttg acctttatat aatcgatgaa tcgaatctgt
     5761 tttagataag attccttcaa tttctaaggg attttccacc ttgacaatca atctagctag
     5821 tttttttctt ccctctacct tacgagtacg catactggga gcttcttcta aaaccagctt
     5881 ttcaagaccc gtttggtcac ctagtgacag aaaggccgat tcttctaaca aggccttcat
     5941 tccaagggtt tcaatataaa atgtttcatt taattttcta ttattagctt ttaaagtagg
     6001 aataatccgt acaatctgat ttacattcat aaattcctcc gtcacttttt attttaaagg
     6061 attttagaat tttttacaag atattatgct caaatttaac attatttagc tatttagtaa
     6121 agatagtctt tcaaggattt tgacaaagcc tgataaccag caatactgag gtgcagtcca
     6181 tcagttgtat attctttttt gagttggcct gcttggtctg tcaaacaatc aaatactggc
     6241 acaaattcca cctgcatata ggcagatgca agctcttgat aggcttgatt ccagttctga
     6301 attttttcat tcgagcggat atagactgcc tgctggtact cctctctctc attgacaggc
     6361 aaaatggaaa gcaatttaat ctctgtcaat ggataatcgc gagcaacgga ttgaatgata
     6421 gcttcgagat tattgagagc ctcattcaca ggaacatcct ttccgatatc atttgtccca
     6481 atcagaagaa aaattttatc tactgctcca ccatatagat gagcatcaag gttctctagt
     6541 aacagtcctg tctgatagcc acgaattcct cgattgacaa tcgtctttga agtcccaaat
     6601 agctcctgta gaggataata ctcgacaatg gaatccccaa taaaaagaat gtttggttct
     6661 acaacagaaa tgtgatttag gtgacgatac ttagtttgaa ttttttcttg ttcctttagg
     6721 agccaatttt ctaataactg tactgccact tcattctcct ttttctaacc agttttccaa
     6781 gacttgataa actcctcctt ggctgttggc tggtgctaga gcagtcgcca cagctttggc
     6841 tttctcatca gcattttcca tcgcataggc aattccagcc atttcaagca tttcaacatc
     6901 attttcacta tcaccaaaag ccatgatttc ttgggatttc aagtcccagc gcttgagtaa
     6961 ttcctccaag ccccatgctt tatgaatccc agcttggagg atatcaatgc aaccatagcc
     7021 actggataca gctcggacac ggccatcaaa gagagcattg atttcttcca aaaccgaact
     7081 caaacgttcc tcaccaacaa ccatgctcat cttgagcaca ccaccaaaga ggtcagatgt
     7141 taattcatcc acaaattgca tccgttggta gaatttttca atcatttctg gagtcataaa
     7201 actttcaaga tctgtaaaaa tcgtaccttc cttgacaaaa tcacccttca tccccgttac
     7261 aacaaactgg tcctgacacg ctcgaccctt gaaatgagtc aaagccttgt tgacaatggc
     7321 gtcatcccat gtctgagcct gaatcaattc attgttttca aaaatacgag cgccattagc
     7381 aacaaccaga accactcgat ccaccaaggg actcagtagt tgtctcatgc ggtgaatttc
     7441 attgcccgtc gcaatgacaa aacgaatgcc cctttgatcc aactgatcta aaatcttttc
     7501 caatcgtggg agatcaagct gacctctagc atccagcaag gtcccatcca tatctgtcgc
     7561 aattacctta atcatcattt actttcctct ggattcaagc taataccact tcaatcccac
     7621 atgttcattc atttctttat aggctgtatc aattcgttcc ttagtcgctt catctaactg
     7681 gtcacgatga ctgccatcct ctataaaatc ttccaaaaca taagtttggt aatgatacaa
     7741 gggatatcct tctggtgaaa aggttccctt tggtgttcga ttgacccaag taggatgagc
     7801 tttagctgtt ccgatagttg tttttccatc cttcttcttg atggtgacat ccatgagaac
     7861 accacgttca gtccacttag cattctcttc atctcccata gattcaattc gttgattgga
     7921 aatgaagttc cccatttaat agacaatgag cttcttatct ccatcttttt ccaccgtttc
     7981 agatggttca acaacgtgag gatgccctcc aaagataata tccgctcccc aatcgatcat
     8041 cttgtgataa agagcttttt gttcttcagt tggttccaat cgatactcaa cacccatctg
     8101 aggcatgata atggtgatat cttcttcctt ctctgcccgt tcaacttcag cctttatctt
     8161 atcttcgttt aaatctgaaa gataacgatt atagtcttcc tgagaaatat actgctcaat
     8221 tccattgaaa ccataggaat aggctaacaa tgcaaccttg atagcattca cttccttaat
     8281 gaccagcgga gcctgatcac gtggttcgtg cgtataaact ccgattggag tgattccagc
     8341 tttctcaata atatcggcca ttgaaataac tccctcaatt tgcgaatcca aaatatgatt
     8401 atgagctaaa tccagcacat gataacctgc ctccttaata gcatccataa cttcaacagg
     8461 agcattaaag agaagataac ccgctaaata atgatcctta ttaatggttc cttcaaaatc
     8521 accaatagct aaatctgctt gcttgagcca aggagtcaca tactcaaaat tttcatgaaa
     8581 gtcataggta ccgtcttctt ttttagctga aaagaaaagt ccatcgtggt agagcaaatc
     8641 cccgtgggcc ataattctgg cagttttttc ctcttcctac tcctgagact tttgcttagt
     8701 cccctcttga gaaatagtat ctcgtttttg actagtcaag ggattccttg gaagctttca
     8761 aacaacaaga ccaagcccat tgataaacca actgctagca agagtatcgc cacaaatccc
     8821 ttattgctcc acttgcgata actcctaaaa agtttaccaa gcccttcata aaacgaaaag
     8881 ctaaaccacc ctgatttcga ttttgtcttc tttgtatctt cattctccct actttcttat
     8941 gcaagccttt tctttttatt atatcacaga taagtatttc tttcacaatt gaattgaact
     9001 tcccatctat tttctataaa tcctaaatgc cataatgctt tcaattcttg tcattttgtg
     9061 atatcatgta gaggtaatga aaggaaatga actaatccac agtggcttat tccaagtata
     9121 ccacttgggc tttggcagta gttaactgca ctaaacataa tataaggaga gaaaatgtct
     9181 gcaatagaac gtattacaaa agctgctcac ttaattgata tgaacgatat tatccgtgaa
     9241 gggaatccta ctctacgcgc gattgctgag gaagtcactt tccccctatc tgaccaggaa
     9301 atcatcctag gcgaaaagat gatgcaattc cttaaacatt cccaagatcc tgtcatggct
     9361 gaaaaaatgg gactccgcgg tggtgttgga ctggctgctc cccagttaga tatctcaaaa
     9421 cgcattatcg ctgttttggt acctaatatt gttgaagaag gcgaaactcc acaggaagcc
     9481 tacgatttgg aagccattat gtacaatcca aaaatcgtct ctcactctgt tcaagatgct
     9541 gctcttggcg aaggagaagg ttgcctgtct gttgaccgta acgtgcctgg ctatgttgtt
     9601 cgccatgccc gcgttactgt tgactacttt gacaaagatg gagaaaaaca ccgtatcaaa
     9661 ctcaaaggct acaactccat tgttgttcag catgaaattg accacattaa cggtatcatg
     9721 ttttacgatc gcatcaatga aaaagaccca tttgcagtta aagatggttt actgattctt
     9781 gaataaagaa aatcccgttg caagacgggg ttttgtgtta taatagaggc atgaaaacaa
     9841 atgatattgt ctatggtgtc cacgccgtta ccgaagccct ccttgcaaat acaggaaaca
     9901 aactctacct ccaagaagat ctccgaggta agaatgttga gaaagtcaag gaactagcta
     9961 cagaaaagaa ggtgtccatt tcttggacat caaaaaaatc tctctctgag atgactgaag
    10021 gtgctgttca tcaaggtttt gttctacgag tgtctgaatt tgcctatagc gagctagatt
    10081 acatccttgc aaaaacacgc caagaagaaa atccacttct attgattcta gatggtctaa
    10141 ccgatcccca taatctgggt tctatcttgc gaacagccga tgcgaccaat gtttcaggtg
    10201 tcatcattcc caagcaccgt gctgtcggag taactcctgt cgttgccaaa acagccacag
    10261 gtgctattga acacgttcca attgcccgag tgacaaacct cagtcaaacc ttagataaac
    10321 tcaaggatga aggcttctgg acctttggaa cggatatgaa cggtactcct tgccacaagt
    10381 ggaatacaaa agggaaaatc gccctcatca tcggaaatga aggaaaaggc atctctagca
    10441 acatcaaaaa acaggtcgat gaaatgatta ccattccgat gaatggacat gttcaaagcc
    10501 tcaatgccag tgttgctgca gccattctca tgtacgaagt ttttctaaat agactataaa
    10561 aaagtttcca gtcatctgat tggaaacttt tttatgatta actatgttct gtgataaact
    10621 tgtaggcttc ttgaccagcg atagctccat ctccaactgc tgttgttact tggcgaaggt
    10681 ctttcaagcg aacatctcca actgcaaaga taccgtcgac tgcagtcttc atgtggctat
    10741 ctgtcacaat ccagcctgcc tgatcttgga tattcaattc tttaacaaaa tcgctaagag
    10801 ggtccaaacc aacatagata aagacaccac cgaaggcttg ctctgtcact tgacctgttt
    10861 tcacattttc aaaaacgaca gattctactc tgttttcacc cttgatttcc ttcactacag
    10921 aatcccagat aaagctgatt ttttcattcg caaaggcgcg atcttgtaaa accttttggg
    10981 cacgaagttg gtcacgacgg tgaacaatgg taacagtctt agcaaaacga gtcaagaaga
    11041 gggcttcttc aacagctgaa tctccaccac caactaccaa taaatcttgg tcacggaaga
    11101 aagcaccatc acacacagca cagtaagaaa caccacgact gttcagttct tcttctccag
    11161 gcactcccaa aggacggtgt ttagaaccag ttgctacaat aactgtacgt gcttcatatg
    11221 tttggtcatc agtcatcact ttcttaaaat caccatggtc ttcgacattt tcaacataac
    11281 cataaatgtg ctcaacacca agattttcaa gtggttcaaa catcttttca gccaattcag
    11341 gtccactaat attagcgtat cctgggtaat tttcgatatc agatgtatta ttcatctgac
    11401 cacctggcag accaccttca atcaaagcta cttttagatt gcttcgagca gcatacaagg
    11461 ccgcagtcat ccctgcaggt ccagcaccga taataatagt atcgtacata tagattcctt
    11521 ctttcttgtt gtaactatct ttattctaac tctttcttgt caatcacgca aggattatgc
    11581 cttgaaaaca agaattaaac tcataaccgc aaaggataat actgggacaa ccaagactcc
    11641 aatcataatc atatcataga gatgggcttg gcgagccttg gctgtcttat caactcccga
    11701 catggctctc agaccaatcc aaatccctaa aaaaatcaga acaaggatgg tggtcaagat
    11761 caaactctcg aaatataaag aaaatagttg cagtagcatg atttctctca tttctatctt
    11821 ttttaaagag taaactcagc tagtccaact aactgagttt tcctttatct attatatcaa
    11881 atataagtcc gtttgtaact agcgaagaat tcttttgtcc gctcttcttt aggggtgtgg
    11941 ataatctcat ccggagttcc agactcgatg attttcccct tatctaagaa gagaatctta
    12001 tccgcaactt gggctacaaa ggacatgtca tgactgacca aaatcatggt ctgacctgac
    12061 ttagcagcat ctgcaataga cttttctact tcaccgacca attctgggtc aagggctgaa
    12121 gttggttcgt ctaagagcaa aacatctggt ttcatagcaa gcgcacgcgc tagggcaacc
    12181 cgttgcttct gtccacctga taaatggcga ggataatggt tttcacggtc cgaaagccca
    12241 accttagcca actcttcctt ggcaatctta gtcgcttctt ggtcagataa tttcttgaca
    12301 acaaccaagc cttctttcac attatcaagt gctgttcggc gttcaaacaa attaaactgt
    12361 tggaaaacca tagacaactt acggcgtagg gcaaggattt cttcttgagt gattttagaa
    12421 aaatcaactg aaaaaccatc aatctgaata gagccactgt caggtgtttc aagataattg
    12481 agactgcgaa gaaaggttga ttttccagct cctgaagaac caatcaaggc tacaacttcc
    12541 cctttttgaa tatccaagtc cagatgatcc aagacagtct gtcctgaaaa ggatttgctt
    12601 aaattcgaaa tcttaatcat taacgaaggt ctcctttcac atctgtttgc actgtatcag
    12661 gtgcagaaat agccattttt ctctcgatga aacgaccgag gctttcaatt ccgatattga
    12721 ctacccaata aacaagggca acggagatga agcgttcaaa atagcgataa tcagctccac
    12781 ctagaatctg agcttgggca aagacttcca caacacccgc actaaaagct agagatgttc
    12841 ccttggtcaa accgatgagg gaattaatca aggttggagt agctaccacc gctgcattag
    12901 gaataatcac tcgtcgataa acttgcgctc gggtcatacc cagactgcgt gccgcctcaa
    12961 tctcaccagg attaactgag agaatggctg cacgaatggt ttcactagca taagctgcct
    13021 cattaaaggc aaaggcgaca atcgcaaaag ctgcagctgg aatcgcattg atattgagac
    13081 cagttcccca ttgctgattg agggctttca aagccaaagg gattccgtag taggtcaaca
    13141 tgagttgcac caaaatcggt gtccctttta agaaactaac aaagaaggcc tgcaagggat
    13201 ataaaatctt gacacgattg atcttcacaa tggcaaaaag aagcgccaaa accaagccaa
    13261 aaagggcacc accaattgtc aacataattg ttgttggaag ttgttggaca attctaggga
    13321 ttccatcaaa gaccgaacgt aggctaaaca gcttgccatc cggaatcaat tgcatcaagt
    13381 tttggtacca atctgatgct aaaatcgttg taacattcat aaaaacatcc tcttctgata
    13441 atgattcatt ctaccatgct tctgccgtca atgaaattat ttgctacggt cagatacaga
    13501 ctttgtctac ctactagttt atcatacttt gaaacaggga agttatatat tttatctatc
    13561 aaagagatag ataaaaacta tttcagtccc agttcttcat aagattttcg ataaccgatt
    13621 tgcttaacgg ttccattttc tactaaaatg ggccgtttta acaacatacc gtcacttgct
    13681 agcaactcag ccgcttcttg gtttgacaaa cttcctacct tatcttttag ccctaattca
    13741 cggtatttga taccactggt gttgaaaaat tgcttcaatt caaatcctga ggtttctagc
    13801 caattcaaaa tgacttcttg gctaggtgtt tcttccacga tatggacggc tttatagtcc
    13861 acacctaatt gatttaattc ttgttttgct tttttacaag ttgaacattt ggggtattcg
    13921 ataaattcta acatgtgctt ctccttctat tgtttctatc tttaaaatct actccttcat
    13981 gctccaagag ccaagctttc ttttccactc ctgcagcata acctgtcaga cgcttatctg
    14041 ctcccaacac acgatgacaa ggtactagga tagaccaagg attgcgtccc actgctccac
    14101 caattgcttg agcagaagcc acttgcaggt cttgagcaat ttgtccatag gttactgtct
    14161 gaccataagg aatgccctgt aaatagtccc aaactctctt ttcaaaattc gttccgattg
    14221 gcgccaagag caagttggat aaatcctgag gcttgccttt aaagtaatca tctaagcaag
    14281 caataactgg gtctaaaata ggatgactaa caacttcttc tatcgtttca tctcctagtc
    14341 ccctctcaaa atgcttctgc tcctgaaccc aaattccata caaataatgg tcatcagcta
    14401 caagtgatag aataccaatt ggtgaggagt agagtatttt tacatacttc ttttgcatta
    14461 tttctttaat ttttgatagg ccaagcgttc gccatctact ggcaccttac caacttgttt
    14521 aaaaccaagt ttttcaaaaa tatgttgcat aaccttgttt tcagcatgcg tatctgagcg
    14581 aaaatcaaga taatcaaaac cttcaatcaa gccctctaag aaggtttgag caactccttt
    14641 tccctgcaca tctgctgcca cagcaatacg gtgaaagact agatactctg actctccagc
    14701 ttgccagttt ccctcataaa tagcttcata ggcctcctct ggactcttgg tcacagcagc
    14761 ataggctagc agttctccct cttccaaggc tacgtaggct tgccctgaga tgatatcatc
    14821 gataataaca tctgcatttg gatagccatt ttgccactgg tcactaccag catctgctaa
    14881 acattttttg gcatcctcca tcacctgcat gatggcatct acttcatttg gaaaagctaa
    14941 acgaatttcc atcttttttc ctcatttctg actagtttct cccatcatag cataatttaa
    15001 gtatttctac aagcagttaa aacttgactt tgtgtttttg ttattttata atctagttat
    15061 caaaactata taaaaaggag ttgaaaatga aaactacctt ttcctaccca aaatgggcag
    15121 aaattccaaa cattgacctc tatctggacc aggttttgct ctatgtcaat caggtctgcg
    15181 cccctatctc tcctaataaa gacaagggcc taacagcatc tatggtcaac aattatgtga
    15241 aaaatggtta cctgacaaag cctgacaaaa aaaaatacca acgccaacag attgcccgtt
    15301 tgattgctat cacaaccctc aagtctgtat tttctattca agaaatagcc cagacactta
    15361 atactctaca aactcaagca agttcagacc aactctacga tgcttttgtg gactacatga
    15421 accaaggaat tgacccagct aaccctatta tccaaaccag ctgccaaacc attaaactct
    15481 atcatcaaac tctagactta atcgatcata ctcaagagga ggtaatccaa tgaacactag
    15541 tcttaaactc agcaaacaac tcagttttgg agaggagatt gctaatagcg tgacccatgc
    15601 tgtaggtgca gtcatcatgc ttatcttgct gcctatttca tccatctata gttatgaagc
    15661 acacggattt ttatcctcta tcggcgtttc cattttcgtc atcagtctct ttctcatgtt
    15721 cctatcatcc accatttatc actctatggc ctatggttcg acccacaaat atgttttgcg
    15781 aatcattgac cattctatga tttacgttgc cattgccggc tcatacacgc ccgttgtctt
    15841 gaccttgatg aataactggt ttggctatct gattattgtc atccaatggg gaacgaccat
    15901 ctttggtatt ctctataaaa tctttgctaa aaaggtcaat gagaaattta gccttgctct
    15961 ttacctgatt atgggctggt tggttctggc tatcattcct gccattatca gtcaaacgac
    16021 acccgttttc tggagtctca tggtaactgg cggactctgt tatacagttg gagctggatt
    16081 ttatgccaag aaaaaacctt atttccacat gatttggcat ctctttatcc tagctgcgtc
    16141 cgcacttcaa tacatcgcta ttgtttatta catgtaaaaa agttgagaaa ttcaatctca
    16201 acttttttct ttacacatat tgataaagta ctggtgcaag cgcacatcat cagtcaattc
    16261 tggatgaaaa gaacttacca acatattttt ttcttgggct gcaacaattt gattgttcac
    16321 tgttgctaga atttctacac cctcaccaac actactgata atcggaccac ggataaaggt
    16381 cattggaatc ttgccaactc ccttacattc tgcttccgtg tagaaacttc ctaattggcg
    16441 cccataagca ttacgctcga ccaccatatc catagttcct agatgactct ctttctgaga
    16501 agtgatttcc ttagccagca aaattaagcc cgcacaggtc ccaaacactg gtaagccaga
    16561 tagaatggct tctcggatgg gaagtagcat gttctggtca cgtaagagct tgcccatggt
    16621 tgtagactca ccaccaggca aaatcaaacc cgacaagtca ctctgatctt gctgaaaatc
    16681 atctagattt ctgagttcta cactctcgac acctaattga tctagcactt ttgcatgttc
    16741 tgcaaaggcc ccttgcaagg ccaatattcc gattttcatc tattttcctc gttcagccat
    16801 gagaatttgg atttcatttt cattaatacc aaccatggct tctcctaaat cttcagagat
    16861 ttgagctagg atttgaggat tacggaagtt agtcacagcc ttaacaatgg cactcgctcg
    16921 tttaacagga tctcctgact tgaaaatacc tgaaccgaca aagaccccct ctgcccctaa
    16981 ttgcatcatt aacgcagcat ctgctggcgt tgcaacacct ccagcagcga aatttacaac
    17041 tggcaatttc ccatgttcat gaacatattg gaccaattct acagggactt gcaaatcctt
    17101 ggcagcaaca taaagctcgt cctcacgtaa gttttgaatg cggcgaattt cctgattcat
    17161 catacgcata tgacgaacag cttggacgat atcccctgtc cctggttctc ctttggtacg
    17221 aatcatggaa gcaccttcag cgatacgacg caaggcttca cccaaatcct tagcaccaca
    17281 gacaaaagga acttggaatt ctttcttgtc cacatggaaa cggtcatcag ctggagatag
    17341 aacttcactc tcgtcgatat aatcaatttc aatagcctct aaaatctgag cttcaacaaa
    17401 atgcccgatt ctgaccttag ccattactgg aatactaacc gcttcttgga tttccttaat
    17461 catctttggg tcgctcatgc gggaaactcc tccagctgca cgaatatcag ccggaattcg
    17521 ttccaaggcc atcacagctg ccgcaccagc agcttctgcg atacgagcct gttcaggatt
    17581 ctgcacatcc ataataacac cacccttgag catctgtgcc aagtttttat ttagttcata
    17641 acgattttca gtcatttgtt ttatcctcat catttgtatt ggtagctacc ttttcatttt
    17701 aagtcagaac agaatgaagc acaagataaa aaaactataa ttgtatgggg acaaattagc
    17761 taaaaactat ctgaccttaa cttaaggcca gatagctcat tcatttttat tttt
//
LOCUS       DAVLZS010000039        16632 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLZS010000039 DAVLZS010000000
VERSION     DAVLZS010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16632
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.039"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            62..1783
                     /gene="pabB"
                     /locus_tag="VYO88_001478"
     CDS             62..1783
                     /gene="pabB"
                     /locus_tag="VYO88_001478"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1719560.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            1784..2401
                     /locus_tag="VYO88_001479"
     CDS             1784..2401
                     /locus_tag="VYO88_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1719561.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            2451..3441
                     /locus_tag="VYO88_001480"
                     /pseudo
     CDS             2451..3441
                     /locus_tag="VYO88_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            3576..4535
                     /locus_tag="VYO88_001481"
     CDS             3576..4535
                     /locus_tag="VYO88_001481"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1719562.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            4632..5471
                     /locus_tag="VYO88_001482"
     CDS             4632..5471
                     /locus_tag="VYO88_001482"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1719563.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVFWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(5519..5689)
                     /locus_tag="VYO88_001483"
     CDS             complement(5519..5689)
                     /locus_tag="VYO88_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1719564.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            5810..6694
                     /gene="miaA"
                     /locus_tag="VYO88_001484"
     CDS             5810..6694
                     /gene="miaA"
                     /locus_tag="VYO88_001484"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1719565.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            6687..7925
                     /gene="hflX"
                     /locus_tag="VYO88_001485"
     CDS             6687..7925
                     /gene="hflX"
                     /locus_tag="VYO88_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1719566.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPIELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKTHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            7918..8541
                     /locus_tag="VYO88_001486"
     CDS             7918..8541
                     /locus_tag="VYO88_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1719567.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            8556..9485
                     /locus_tag="VYO88_001487"
     CDS             8556..9485
                     /locus_tag="VYO88_001487"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1719568.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGVKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            9506..10261
                     /locus_tag="VYO88_001488"
     CDS             9506..10261
                     /locus_tag="VYO88_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1719569.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(10315..11223)
                     /locus_tag="VYO88_001489"
     CDS             complement(10315..11223)
                     /locus_tag="VYO88_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1719570.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            11287..11556
                     /locus_tag="VYO88_001490"
     CDS             11287..11556
                     /locus_tag="VYO88_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1719571.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLKAEAVLRREHKVELDYIEKNGEKN"
     gene            11556..11936
                     /locus_tag="VYO88_001491"
     CDS             11556..11936
                     /locus_tag="VYO88_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1719572.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            12025..12252
                     /locus_tag="VYO88_001492"
     CDS             12025..12252
                     /locus_tag="VYO88_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719573.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVFSISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(12292..13017)
                     /locus_tag="VYO88_001493"
     CDS             complement(12292..13017)
                     /locus_tag="VYO88_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1719574.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSFSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            13179..15020
                     /gene="typA"
                     /locus_tag="VYO88_001494"
     CDS             13179..15020
                     /gene="typA"
                     /locus_tag="VYO88_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1719575.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPVEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            15040..15294
                     /locus_tag="VYO88_001495"
     CDS             15040..15294
                     /locus_tag="VYO88_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1719576.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            15658..15957
                     /locus_tag="VYO88_001496"
                     /pseudo
     CDS             15658..15957
                     /locus_tag="VYO88_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            16028..>16632
                     /locus_tag="VYO88_001497"
     CDS             16028..>16632
                     /locus_tag="VYO88_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1719577.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHS"
BASE COUNT         4913 a         3128 c         3768 g         4823 t
ORIGIN      
        1 aaaatcgtaa aaaggtagat cagctttgtc tgtatctgcc tttttatgct atacttaagg
       61 tatgcataga aaaacagtga ttgattttag gactttaggg gagagatata cctttaccca
      121 gcctattaaa gagttgaaaa cgagaaatgt agaagaagtg gcagatttgc tggcacaagt
      181 ggaaagctac caagagcaag gttattatgt ggtggggtat gtcagctacg aggctgcacc
      241 tgcttttgag gaaaaattag cagttcacaa ggatccccta ctgggagagt acctgcttta
      301 ttttactgtt catgatagcg tagaaacttc ccctattcct ctgacttatg aggatattga
      361 tttgccttca aattggcagg aagtaacgtc tgcagcagac tatgaaaagg ccattgccca
      421 gatacaccat cacttgaggc agggagacac ctatcaggtc aactacaccg tccaactcaa
      481 gcaaaagtta agtgccaatc cttttgccat ctacaatcgt atggtggtag agcaggaggc
      541 gggctacaat gcctatgtgg aacatgacga gatggcagtg atttccatga gcccagagct
      601 cttttttgag caaaatgatc gcgagttgac aacacgacca atgaagggga cgactcagcg
      661 tggggtaact gaccaagaag atcttgaaca ggccagttgg ttggaacagg atcccaaaaa
      721 tcgctctgaa aatatgatga ttgtggacct cttgcgcaat gatatgaacc gtatttctga
      781 agttgggagc gagcacgtgg agcgtctgtg tcaggtagag cagtattcaa ctgtttggca
      841 gatgacttcg accatcaaga gtcagttgcg agaggatgtg gaccttgttg aaatcttccg
      901 ctcactcttt ccttgtggtt ccataacggg tgcaccgaaa attgcgacaa tggagattat
      961 caaggacttg gagcctcaac cgcgtggagt ctactgtgga acgattggtc tcttgcttcc
     1021 aaatggacga cggattttta atgtggccat tcgtaccatt caacttcaca aaggtcaagc
     1081 catttatgga gttggcggag ggattacttg ggatagcaca tgggaatctg aataccgaga
     1141 ggttcatcaa aaggcagcag ttctttatcg taaacaagct cgcttccaac tgattacgac
     1201 aggggaaatc agccagaaga acctgctgtt tgaagatcaa catctggaaa gactgagaaa
     1261 agctagtcgt tattttgctt ttccttttga tgcagaagac ttgggacaca agattgagga
     1321 agagtgtcag gattgtgaag ctaatcgaga ttaccgcttg cgaatcagcc ttagcaaatc
     1381 tggagagata gaagtcaatc gtcaagtatt aacccctctc agtacaagct tttgtcaggc
     1441 ccaagtctgt cttcaggaag ctgctttgaa tcaatccttt acctacttta aaaccactca
     1501 ccgaccgcat ttgagcctag gagaacaaga gaagatttac cacaataagt caggagaact
     1561 gcttgaaacc tctataggaa atttggttct gaaaatcgct ggaaaactct acacaccgcc
     1621 tatccgactt ggaatcttgc caggaattta ccgtcagcat ttgctagaaa caggacaggt
     1681 agaagagaaa gtcttgacct tggcagattt aacccaagca gaagctattt acggctgtaa
     1741 tgcagtgaga ggcttgtatg aactaagcct tgaggagaac tagatgaaat tgatattttt
     1801 gcatgggtta gggcagtcag cagagtcttg gaaagaagtt cggaatctac tgacagatta
     1861 tccttctgag gctatcgagt tatttccttc tggagttagt aactatcaac aagctaaaga
     1921 gcgagtttat cagcacctag ctcaagagac agaacctttt gttttgattg gattgtcctt
     1981 aggtgctgcc ctgacactag aactttccag ttacgattta ccaaatcttc gagctttgat
     2041 tctgtcagga tgcccgctta aattagcagg gaatatccta ttttatcttc agttgctgat
     2101 ttttaaacta cttcccaaaa gagtatttga aaaacaggga gcagacaaga ctcttatggt
     2161 cggagtttct gaggaattga agacacttga tttaacggat atagcaggga cttgctccta
     2221 tccaacctta ctaatttgtg gcagcaaaga taaaccgaat cttagttcta tgaaagctct
     2281 ccatagactg ttaacagatt cgcagtttca gatcattcct gatggccctc atgtcttgaa
     2341 taaggcaaaa ccaaaggagt ttgtagaaaa gaccagaagt ttccttgaat tgctgaaata
     2401 agtttgataa aataatattg aaatcgatat cataattatg ggagaaagaa atgaataaac
     2461 gtctattttt aaaaatgagt ctggtgacgt tgccaatttt agccttgttt tcacaaccag
     2521 ttttggcgga agaaaacatc catttttcga gctgtaagga agcttgggcg aatggctatt
     2581 cggatattca cgagggagaa cctggttatt ctgccaagtt agaccgtgat catgatggtg
     2641 tggcttgcga attgaaaaat gctcctaagg gtgcttttaa agcaaaacag tcaacggcta
     2701 ttcaaatcaa cacaagttca gcaacaacaa gtggttgggt taagcaggac ggcgcttggt
     2761 actactttga tggaaatgga aatctagtga aaaatgcatg gcagggaagc tattacctga
     2821 aagctgatgg taaagtggca cagagtgaat ggatttatga ctcttcttat caagcttggt
     2881 attatttgaa atcagatggt tcttatgcaa aaaatgcatg gcaaggagct tattacctta
     2941 aatcaaacgg taaagtggca caaggtgagt gggtttatga ttcttcttac caagcatggt
     3001 attacttgaa atcagatggt tcatatgctc gcaatgcatg gcaaggaaac tactatttga
     3061 aatcagatgg taaaatggct aaaggtgaat gggtttatga tgccacctat caagcttggt
     3121 attatttgac atcagatggt tcttatgctt acagtacatg gcaaggaaat tactatctaa
     3181 aatcggatgg taaaatggct gtcaatgaat gggttgatgg tggacgttat tatgttggcg
     3241 ctgacggagt ttggaaggaa ggtcaagcaa gtacagtttc ttctagtaat gatagcaata
     3301 gtgaatattc tgctgcttta ggaaaggcaa aaagttataa ttcgttattc cacatgtcaa
     3361 aaaaaacgta tgtatagaca attaacttct gattttgata aattttcaaa tgatgcagct
     3421 caatatgcca ttgatcatta gatgattaac agatactggt aggcgaaaaa attccttata
     3481 attcatttac gcaaaccttt gcataagtga atggattttg atatactagt actgtaagca
     3541 ttttcaatta ctacacaatg aaaaaggaga atatgatgag tcaaaagatt attgggattg
     3601 accttggtgg aacttctatc aaatttgcaa tcttaacaac agcaggagaa atccaaggaa
     3661 aatggtcaat caagaccaac attttggatg agggtagtca tatcgttgat gatatgattg
     3721 agtctattca acatcgtttg gacttgcttg gattggcagc agcggacttc caaggcattg
     3781 gaatgggatc accaggtgtg gttgaccgtg acaaagggac tgttatcggt gcctacaact
     3841 tgaactggaa aacccttcaa ccaatcaaac aaaagattga aaaagccttg ggcattccat
     3901 ttttcatcga taatgatgcc aacgtagcag ctcttggtga gcgctggatg ggtgctggag
     3961 ataaccaacc agacgttgtc tttatgacac tcggtactgg tgttggtggt ggtattgtcg
     4021 cagaaggcaa attgcttcat ggtgttgctg gtgcagcagg tgaacttggt catatcactg
     4081 ttgattttga ccaaccaatt gcatgtactt gtggtaaaaa aggctgcctt gagacagttg
     4141 cttcagcaac agggattgtc aacttgactc gtcgctatgc cgatgaatac gaaggcgatg
     4201 cagccttgaa acgcttgatt gataacggag aagaagtaac tgctaagact gtctttgatc
     4261 tcgcaaaaga aggagacgac cttgctttga ttgtttaccg taacttctca cgttacttgg
     4321 gaatcgcttg tgctaacatt ggttcaatcc taaacccatc aacaatcgtc atcggtggtg
     4381 gtgtgtcagc tgcgggagaa ttccttctac aaggtgttca aaaagtttac gatgaaaata
     4441 gtttcccaca agtacgaaca tctactaaat tagctcttgc aactctagga aatgacgctg
     4501 gagttatcgg agcagcatca cttgtattgc aataagataa tgagagagga aaatactaac
     4561 ctagagttag taatgttcct cttttatttt ttatgctata ctagttagga caatgaatga
     4621 ggtgagagta aatgacaaaa gcagatacga tttttaaaga gaatattgaa cgcattctaa
     4681 aggaaggtgt tttctcagag caggctcgtc ctaagtacaa ggatgggact gttgctaatt
     4741 ccaagtatgt aactggtgcc ttttccgagt acgacttatc taaaggagaa tttcctatca
     4801 caaccttgcg tcccattgca atcaaatccg ccatcaaaga agttttctgg atttaccaag
     4861 accagtcaaa tagcttagaa gtgcttaatg acaagtacaa tgttcactac tggaatgact
     4921 gggaagttgg agacacggga accattggtg agcgctatgg tgccgttgtt aagaaacacg
     4981 acattatcaa taagcttctc aaacagttgg aaaccaatcc ttggaaccgc cgcaatatta
     5041 tttcgctctg ggattaccaa gctttcgaag aaacagatgg gctgctcccg tgcgcctttc
     5101 agaccatgtt tgatgtccgg cgtgttgatg gggaaatcta tctggatgcg accttgaccc
     5161 agcgctccaa tgatatgctg gtggcccacc acatcaacgc tatgcagtat gtggctttgc
     5221 agatgatgat tgccaaacat tttggctgga aggttgggaa gttcttctac ttcatcaaca
     5281 acctccatat ctatgataat caatttgaac aagctcagga attgctccgt cgggagccgt
     5341 caaactgcca accacgcttg gttttaaatg ttcctgatgg gactaatttc tttgatatca
     5401 aagcagaaga ttttgagttg gtggattatg accctgttaa gccacagttg aagtttgacc
     5461 tagctattta aaagaataga aaaaagaagt tgagaataat cccaacttct tttgtttctt
     5521 aacgtgatac gcggcgacga gctgcttttt tacggttttc ttcgatgaaa gctgcttttt
     5581 gctcttctgg ttcgattact ttctttttaa atgcgtatac tgcacctgca acggcagcga
     5641 cagttcctgc gacacctgtt acaagacctt tagcgaatcc tttagccatg agtcttcctc
     5701 ctttatattc tcaatcagcc agcctcctca agaggtcaca tttttctgac tgaccttttt
     5761 gtgttataat aatagtaacg aaaaaatggg aatttttcaa ggaaaaaaga tgaaaacaaa
     5821 aataattgtg attgttggac cgactgctgt tggaaagacg gctctagcta ttgaagttgc
     5881 aaagcgcttt aatggcgaag tggttagtgg agatagccag caagtctatc gaggacttga
     5941 tattgggacg gccaaggcta gtccagaaga gcaggcagct gttcctcatc atttaatcga
     6001 tgttagagag ataaccgagt cttactcggc ttttgatttt gtttcagaag ctaagatgac
     6061 tattgaggat attcacagcc gtggcaagct agccattatc gccggtggga ctggacttta
     6121 tatccagagc ttgctagaag gttaccacct aggtggggag actcctcatg aggagatttt
     6181 ggcttatcga gctagtttgg agccatattc agatgaggaa ttagcccatt tggtggagca
     6241 agcaggcctt gagattcccc agtttaatcg tcgtcgtgct atgcgtgcct tagaaattgc
     6301 ccattttggt caggatttgg aaaatcaaga gaccttgtat gaaccgctga ttatctgctt
     6361 ggatgatgaa cgtagtcaac tttatgagcg tatcaaccac cgagtggatt tgatgtttga
     6421 ggctgggctt ttggatgagg ccaagtggct gtttgaccat tcccctaatg tacaggctgc
     6481 taaaggaatt ggctataagg aactctttcc ttatttccgt ggagagcaga ccttggagga
     6541 agctagtgag agtcttaaac aggcgactcg tcgttttgcc aagcgtcagc tgacctggtt
     6601 ccgtaatcgc atgcaggtca ccttttatca gattggagaa tctggtgtac aagaccgcat
     6661 tttaagccag atagaggagt ttttagatga ttgaaacgga gaaaaaagag gagcgagtcc
     6721 tgctgattgg tgtggaattg cagggtatgg acagttttga cctctccatg gaagaattgg
     6781 ctagtttagc gaaaacggca ggggcagtcg ttgtagatag ctacagacaa aaacgtgaaa
     6841 aatatgattc caagaccttc gtcggctctg gtaagttgga agagattgcg cttatggtgg
     6901 atgcagaaga aatcactact gtcatcgtca acaatcgtct gaccccaagg cagaatgtca
     6961 atctagagga agttctcggt gttaaggtca ttgaccgtat gcagttgatt ttggatatct
     7021 ttgccatgcg ggctcgaagc catgaaggga agctccaagt ccacctagct caactcaaat
     7081 acctcttgcc tcgcttggtt ggtcagggga ttatgctcag ccgtcaggca gggggaattg
     7141 gttcccgtgg tcctggtgaa agccaactgg agctgaaccg tcgtagcgtt cgcaatcaaa
     7201 tcacggatat cgagcgccag ctcaaggtgg ttgagaaaaa tcgtgcgact gtcagagaaa
     7261 aacgtttgga gtctagcact tttaagattg gtttgattgg ttataccaat gctgggaaat
     7321 caactatcat gaacatcttg accagtaaga cccagtatga agcagatgag ctctttgcga
     7381 ctctggatgc gacaaccaag agtattcatc tgggaggcaa cctccaagta actttgacag
     7441 ataccgttgg ctttatccaa gatttgccga tagagttggt gtccagtttc aagtcaacct
     7501 tggaagaaag caagcatgtg gaccttctgg ttcatgttat cgatgctagc aatccttacc
     7561 acgaggaaca tgaaaaaacg gttctctcca tcatgaaaga cctggacatg gaagatattc
     7621 ctcacttgac gctttataat aaagcggatt tggtagagga tttcacgcct acccaaacgc
     7681 catataccct catttctgcc aagtctgagg acagtcgtga aaacttgcaa gcattattgc
     7741 tagataagat taaggaaatt tttgaagcat ttaccctgcg agtgcctttt tcaaagtcct
     7801 acaagactca tgatttagag agtgttgcaa ttctggaaga acgtgattat caggaagacg
     7861 gcgaagtgat tacaggctac atttccgaga aaaataaatg gaggttagaa gaattttatg
     7921 actgatatta aaactttggc tctaaagtat ggaggttata caagtctgga caaggtctat
     7981 ctggatcagc ttctagctgg taagacagag caggagcagt taacacttat tacacctccg
     8041 ccaagtgttg ttaatgccta ctttgcagaa ctctatcaga aaaaaagtcc tcaggctgcg
     8101 acggattatt ttgcagaact cagtcaggaa ctgaatcttt acaatactga gccaagtttc
     8161 accctagaaa ataagtcttt tattcggctt aatctgtctg gtaaatcctt tggtttttgt
     8221 tatgagagtg acggctttgg tcggattttc tctgaaaatg aggagaaaat ctcggatgac
     8281 ttgctctttg aaattgcgca aattttcccc catcaactag tctttgaaga gtctggtaag
     8341 atttacatga agcctgtcga ggacgaggaa gttgtcagcc tagaaagtct cacagctttg
     8401 actgatttgg aaagattggc tgatggtcga aaacgtctca aaggctacag ccaagaggat
     8461 ttattgcaag aagctgctgc tttttctggc aaacgctatt tccgatcgga aaaccgcaca
     8521 gccatgttat atattgatta attagaaagt atcgaatgga tattcaattt ttaggaacgg
     8581 gggctggtca gccctctaaa gctcgcaacg tttcaagtct cgccctgaaa cttttggacg
     8641 agattaacga agtttggctc tttgactgtg gagaaggtac gcaaaatcgc attctggaaa
     8701 ccacaattcg accacgtaag gtcagcaaaa tctttattac ccatctgcat ggagaccaca
     8761 tttttggttt gccaggtttc ctttctagcc gtgcctttca ggccaatgaa gagcagacag
     8821 atttggaaat ctacggacct caaggaatca agtcatttgt cttaaccagc cttcgtgtgt
     8881 caggttctcg tctgccctac cgcattcatt tccatgagtt tgaccaagat tctctgggta
     8941 aaattcttga aaccgataaa ttcactgtgt atgcagagga gctggaccac actattttct
     9001 gtgttggcta tcgtgtcatg caaaaggatc tagaagggac gctggatgct gaaaaactta
     9061 aggctgctgg tgttccgttc ggcccgcttt ttggtaaaat caaaaacggc caggatcttg
     9121 ttttggaaga cggaactgaa atcaaggcag cagactatat ctcagcgcca cgtccaggta
     9181 agattatcac tattttagga gatactcgaa aaacggatgc cagtgtgcgt ctggctgtca
     9241 atgcagatgt cctagttcat gagtccactt atggcaaggg tgatgaaaaa attgctcgta
     9301 accatggtca ctcaactaat atgcaagctg cacaagtagc ggtagaagca ggtgtcaaac
     9361 gcctcctact caaccatatc agtgcccgtt tcctctcaaa agatattagc aaactcaaga
     9421 aagacgctgc cacaattttt gaaaatgtcc atgtggtcaa agacttggaa gaagtggaaa
     9481 tctagcagtc acagaaagga taagtatgcc tactattctc attaccggag ctagcggtgg
     9541 tctagctcaa gaaatggtca aactcctgcc caatgaccaa ctcatcttgc ttggtagaaa
     9601 taaggaaaaa ttagcccaac tctacggaaa ttattcccat gcagaattga ttgaaattga
     9661 tattaccgac gattcagccc tagaagctct ggtaactgat ctttatctcc gctatggcaa
     9721 gattgatgtc ttgattaaca acgctggtta cgggattttt gagggatttg accaaattgc
     9781 tgataaagac attcaccaga tgtttgaggt caataccttt gccctgatga atctgtctcg
     9841 tcaccttgcg gctcgtatga aggaaagcag caaagggcat atcatcaaca tcgtcagcat
     9901 ggcaggtcta atagctactg gcaagtctag tctttactca gcgaccaagt ttgcggctat
     9961 tggtttttca aatgctctgc gactcgaact tatgccctat ggagtctatg tgacaacagt
    10021 caatccaggt ccaatccgaa caggattttt tgaccaagct gacccagatg gaacttatct
    10081 taaatcggtt gaccgcttcc tcttagaggc agatgcagtg gctaaaaaga ttgtcaagat
    10141 tataggaaaa aataaacgag aactcaatct cccgattttg ttgaacctag cccataagtt
    10201 ttatactctc tttcccaagc tagctgataa gttggcaggg gaaactttta attataagta
    10261 aaaagaacca atgtgcaggt tgttgctagc ctacatattg gttcttatca tttctcaact
    10321 atcaaactga acttcttcta gtagatagtc gataaagcgt tcgcccatct tagataggct
    10381 ggttttctca tgctggatat agaccagctc gatcgggtca tcaatatcca gtgggataga
    10441 aacgatattg tctccgttta ggttgctgtt caaaatccct gtcgcaatgg tataaccatc
    10501 caaaccaatc aagagattaa agagggtggc acggtcactg accacaatgg atttcttgtg
    10561 gtgttcttga gaaagaatct cttctgaaaa gtagaaggag ttgtgcgtcc cttggtcata
    10621 gctgaggtaa gggaaattct ccaaatcaga cagtttcacc ttgtctttct ttgccagagg
    10681 gttggtcttg ctgacaaaga tatgcggttg cgctgtgaag agatggtggg ctagcaggtg
    10741 attgtcatcc agcatcttgg ttaaaacatc acggttgtaa ctgtttaaga agaggacccc
    10801 gacctcactg cggaagttct tgacgtcgtc gataatctcc caagtccgag tttcacgaag
    10861 gaagagttcg tatttctcca tatcgctttt cttgagcaaa gagacaaagg cattgaccac
    10921 aaaggcatag tgttgagacg aaacgctaaa tagttcgcgg tgggcgacag gatttttata
    10981 gcgttcctcc agaagctggg tctgctcgac aacctgacgg gcataagaga gaaactccat
    11041 cccatcacgg gtcaaggtga ttcccttggg attgcggata aagatctcaa tgcccatttc
    11101 attttccaaa tctcgcactg cattggagag acttggctga gtgataaaga gttgcttggc
    11161 tgcctcattc atggagccag tttcgacgat tttgataata taatgtaatt gttgaattct
    11221 catgttttta ttgtaccata cttgccttag aatcgctaaa gaagatagga aaataaggag
    11281 cattgtgtga gtctcttctt gaaaaaaaca caaaattttg ctagaatgag tcttatgaaa
    11341 acattctatg atgtgcagca attcctcaaa cgatttggta ttattgttta catgggaaaa
    11401 cgcttatatg atattgaact gatgaagttg gaactatctc ggatttacga tgcagggttg
    11461 atggataaat tagactatct aaaggcagaa gcagttcttc gcagagagca caaggtagaa
    11521 ttggattata ttgagaaaaa tggagaaaag aactaatggt tacttggatt ttgtgggcac
    11581 ttatactagc aatgttggcg tggatgggct ttaactatct tcgtattcgc cgtgcggcta
    11641 aaattgtgga caatgaggag tttgaagcct tgattcgtac gggtcaattg attgatttgc
    11701 gcgacccagc agaattccac agaaaacata tccttggtgc acgcaatatt ccttcaagtc
    11761 agttgaaaac tagtcttgca gcccttcgta aagataaacc tgtccttctc tacgaaaacc
    11821 aacgtgcgca acgagttaca aatgcagctc tttacttgaa aaaacaaggt ttttctgaga
    11881 tttatatcct ttcttatggc ttggattctt ggaaagggaa agtgaagact agctaacctt
    11941 atttccaaat tagtcgaatg ataggatgaa gctattgttt tatagtataa ttaatttgta
    12001 taaaatttaa agagttctta gaacatgaaa gaaaagaaga aaaatccact ttttgtgggt
    12061 atcttgtcga ttattcttgg tttgttattt ccaattgtag gcctgatttt gggtatcata
    12121 ggattggtct tttctatttc ataccaaaaa gagtcacaat tagactataa aatagaaaag
    12181 attcttaata tcttaggaat tgtgatttct gtagttaact ggattgtagc aatcgcctta
    12241 atttttcggt aaataaaaga aaaaagtttt agttttaaag ctttttttgt tttatcgact
    12301 catctctaaa tagtttttaa tgatttgtaa ctctttttgg ttcaaagggc ggtagttact
    12361 ttctgctaaa tctgggttca atgtgaagtc cccaaattgg attctcttga ggctagtcac
    12421 cttaacacca accgagagga acattttctt gatttgatga aattttcctt ctgaaatggt
    12481 gatagaggct tgactgaagg aaggacttgc tgatagaatc tctagtcttg caggtttaca
    12541 gatagtgcca tctaaaaaga caattccttt ttgaaaggtt tggatatggt caggtgttag
    12601 aagtccatta acctggactt ggtaagtctt atcgacatga tattggggat ggaggagttg
    12661 gaagcccaag ggaccgttat cggtcaagag aaggagtcct gttgtatctc ggtccagtcg
    12721 gccgacggca tagagcttgt cagactggat gtcagatgga agcaggtcca tgacggtcgg
    12781 aagttccttg tctttgttgg ctgtaacgac accagcaggt ttatgaagca taagataggt
    12841 gtgttcatag ccttgaatga ttcgatcctg aaaaaggagt tcttgtagtc ctgtatcgat
    12901 attttgagct agggagcggg ctgggcaacc atcgactaga atttcccctc tgaggagtgc
    12961 ttgcttcatg gcctttcggc tgattttttc ttgggctaat aaattatcta aacgcatact
    13021 gtgcctatct tatcataagt cgctcgcttt gaaaaggctt gacgtgaaaa gaaaagcaga
    13081 gtgaaaacat ttacacttgc ttgagttatg ttatttactt gaaattatgg tataatcgtt
    13141 cagttagaaa ataaattttg aatattatag aggaaatcat gacaaaatta agagaagata
    13201 tccgtaacat tgcgattatc gcccacgttg accacggtaa aacaaccctg gttgacgaat
    13261 tattgaaaca atcagaaacg cttgatgcac gtactgaatt ggcagagcgt gctatggact
    13321 caaacgatat cgaaaaagag cgtgggatta ccatccttgc taaaaatact gccgttgctt
    13381 acaacggaac tcgtatcaac attatggaca caccaggaca cgcggacttt ggtggagaag
    13441 ttgagcgtat catgaaaatg gttgacggtg ttgtcttggt cgtagatgcc tatgaaggaa
    13501 ccatgccaca aactcgtttc gtattgaaaa aagccttgga acaagacctt gtcccaatcg
    13561 tggttgttaa caaaatcgat aagccatcag ctcgtccagt agaagtagtg gatgaagtct
    13621 tggaactttt catcgagctt ggtgcagatg acgaccagct tgatttccca gtggtttatg
    13681 cttcagcgat caacggaact tcttcattgt cagatgatcc agctgaccaa gaagcgacta
    13741 tggcaccaat ctttgacacg attatcgacc atatcccagc tccagtagat aactcagatg
    13801 agcctttgca gttccaagtg tcgcttttgg actacaatga cttcgttgga cgtatcggta
    13861 tcggtcgtgt cttccgtggt acagttaagg ttggggacca agttaccctt tctaaacttg
    13921 acggtacaac taaaaacttc cgtgttacaa aactcttcgg tttctttggt ttggaacgtc
    13981 gtgaaatcca agaagccaaa gcgggtgact tgattgccgt ttcaggtatg gaagacatct
    14041 ttgtcggtga aaccatcact ccgacagatg cagtagaagc tcttccaatc ctacacatcg
    14101 atgagccaac tcttcaaatg actttcttgg tcaacaactc accatttgct ggtaaagaag
    14161 gtaaatgggt aacctctcgt aaggtggaag aacgcttgca ggcagaattg caaacagacg
    14221 tttcccttcg tgttgaccca actgattcac cagataaatg gactgtttca ggacgtggag
    14281 aattgcactt gtcaatcctt atcgaaacaa tgcgtcgtga gggctatgaa cttcaagtat
    14341 ctcgtccaga agttatcgta aaagaaatcg acggtgttaa atgtgaacca tttgaacgtg
    14401 tacaaatcga cactccagaa gaataccaag ggtctgttat ccaaagcctt tctgaacgta
    14461 aaggtgaaat gttggatatg atttcaactg gtaatggtca aactcgtttg gtcttccttg
    14521 ttccagcgcg tggtttgatt ggatactcaa ctgagttctt gtcaatgact cgtggttacg
    14581 gtatcatgaa ccataccttc gaccaatact tgccattgat tccaggagaa attggtggac
    14641 gtcaccgtgg tgcccttgtt tctatcgatg ctggtaaggc tacaacttac tcaatcatgt
    14701 ctatcgaaga acgtggtacg atctttgtca acccaggtac tgaggtttat gaaggaatga
    14761 tcatcggtga aaactctcgt gaaaatgact tgacagttaa catcacgaag gcaaaacaaa
    14821 tgaccaacgt tcgttcagct actaaggacc aaacagctgt tatcaagacg cctcgtatct
    14881 tgacacttga agagtctctt gagttcttga acgacgatga gtacatggaa gtaacgcctg
    14941 agtctatccg tttgcgtaaa caaatcctta acaaagcaga gcgtgagaaa gctaacaaga
    15001 agaaaaaatc agctgaataa gagctagaaa gagagaaaga tggtctattt agtcctagga
    15061 attttactgc tcctactcta tgtatttgcg acaccagaaa gcattaaagg gactgtcaat
    15121 atcgtcgcta tggtatgtat tttagtggca ctcttgattt tattggttct atcttttctg
    15181 aaaatttttc aattaccaac agaaatattc ttagcaatag ccatgttgat cctagcttac
    15241 tttagtgtta gagacatcac actcatgcca gtcaaaaaaa gtaaaagaag ataaaaaaga
    15301 gagtttcggc tctctttttg ctaggaattt tacaatagtt tgaattgctt tttagttaac
    15361 accatctctt ttacttgtat agtatgaatg ggaaaaactt gaataaaatt cgttaatggc
    15421 atctatttta tatttggtta gtactggttg catattattt tgaaataaaa ctactatata
    15481 atattattca cagaggtaat atagtaaaat atctaaaaaa ttcgattttt tccttgacaa
    15541 caaataataa aaaagttatt cttatcacat aagaaagcgg tttcaataaa agagagagga
    15601 ggatttattt tgttgcattg ttgctcaagg tgtgcttttt ttgaaagaaa aaataaaatg
    15661 aaaacgaaaa aacatagatt acttgctcta gctcttattt caaattttac attattggga
    15721 gctgcatcag ctgctgtaca atatccagat ggaggagtat ggacatatgg agaaggttca
    15781 ggaggtggtt aggctttttc aaattactat catggtaaaa aatatcatta ttcatccatc
    15841 gtgagcagat gggatggtca ttctgataaa ggagaagctc ctgctggaaa aacctcctat
    15901 gcatggattt ggactaaatg gggagaacaa gtagcatttt actgtgatta tgactaatcg
    15961 ttcattgatt taaatcgttc cccttgtaag aaattacagg gggaattttg tttacaagga
    16021 gtctactatg aagaaactat tcatattatt atcaactttt tttctcagct tcttccttgc
    16081 ttggattatt gtcttacgtg cgccacaata tttatatgca agctatgatt ccgtttcttt
    16141 acttcgtgtc aaaaaagata ctcaggaacc gacgcgtgag gtatttgaac aggaattgga
    16201 gaattttgca aactcagaac agagtttaat agctagaaga attgtagagc cgagtaagga
    16261 tgggacgact cactttactt atgcaactta tggtcaggga actttaccaa aagaattcca
    16321 agaagctagc caagaaagtc gtgaacgtag tgatccgcta aatagttatc tccttttgtc
    16381 aggctccttg acgaaagaaa agcttgccga taaattagga gatttgggtt ataaagcaag
    16441 tgctgaccga aagataccgc cctattttct tgcttttcga atattactaa atccccttat
    16501 tttaattagt ttagcaatat ttggcttatc tttctttgct ttagtgatta tcactcggat
    16561 taaggaaatg agagcagcag gtataaaact cttttctggt cagactctct tatccatcat
    16621 ggggcattct tt
//
LOCUS       DAVLZS010000040        16173 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLZS010000040 DAVLZS010000000
VERSION     DAVLZS010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.040"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(65..1687)
                     /gene="groL"
                     /locus_tag="VYO88_001498"
     CDS             complement(65..1687)
                     /gene="groL"
                     /locus_tag="VYO88_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1719578.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1703..1987)
                     /gene="groES"
                     /locus_tag="VYO88_001499"
     CDS             complement(1703..1987)
                     /gene="groES"
                     /locus_tag="VYO88_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1719579.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2143..2538)
                     /locus_tag="VYO88_001500"
     CDS             complement(2143..2538)
                     /locus_tag="VYO88_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1719580.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2616..3377)
                     /locus_tag="VYO88_001501"
     CDS             complement(2616..3377)
                     /locus_tag="VYO88_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1719581.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3410..4036)
                     /locus_tag="VYO88_001502"
     CDS             complement(3410..4036)
                     /locus_tag="VYO88_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1719582.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4052..4369)
                     /locus_tag="VYO88_001503"
     CDS             complement(4052..4369)
                     /locus_tag="VYO88_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1719583.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4366..4665)
                     /locus_tag="VYO88_001504"
     CDS             complement(4366..4665)
                     /locus_tag="VYO88_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1719584.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5002..5193)
                     /locus_tag="VYO88_001505"
     CDS             complement(5002..5193)
                     /locus_tag="VYO88_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1719585.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5354..6028)
                     /locus_tag="VYO88_001506"
     CDS             complement(5354..6028)
                     /locus_tag="VYO88_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719586.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6034..6480)
                     /locus_tag="VYO88_001507"
     CDS             complement(6034..6480)
                     /locus_tag="VYO88_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719587.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6594..7097)
                     /locus_tag="VYO88_001508"
     CDS             complement(6594..7097)
                     /locus_tag="VYO88_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1719588.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWNICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7094..7456)
                     /locus_tag="VYO88_001509"
     CDS             complement(7094..7456)
                     /locus_tag="VYO88_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV1719589.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7522..9381)
                     /locus_tag="VYO88_001510"
                     /pseudo
     CDS             complement(7522..9381)
                     /locus_tag="VYO88_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(9420..9869)
                     /locus_tag="VYO88_001511"
     CDS             complement(9420..9869)
                     /locus_tag="VYO88_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1719590.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKPVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(9993..10709)
                     /locus_tag="VYO88_001512"
     CDS             complement(9993..10709)
                     /locus_tag="VYO88_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1719591.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11590..13005)
                     /gene="ply"
                     /locus_tag="VYO88_001513"
     CDS             complement(11590..13005)
                     /gene="ply"
                     /locus_tag="VYO88_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1719592.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13016..13348)
                     /locus_tag="VYO88_001514"
     CDS             complement(13016..13348)
                     /locus_tag="VYO88_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719593.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13419..14027)
                     /locus_tag="VYO88_001515"
     CDS             complement(13419..14027)
                     /locus_tag="VYO88_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719594.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSAAQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14040..14498)
                     /locus_tag="VYO88_001516"
     CDS             complement(14040..14498)
                     /locus_tag="VYO88_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1719595.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14623..15022
                     /locus_tag="VYO88_001517"
                     /pseudo
     CDS             14623..15022
                     /locus_tag="VYO88_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15787..16047)
                     /locus_tag="VYO88_001518"
     CDS             complement(15787..16047)
                     /locus_tag="VYO88_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719596.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
BASE COUNT         4764 a         3688 c         2922 g         4799 t
ORIGIN      
        1 ataaaaagaa gggttagtca ttccctcctt ttgtgttttt tataagttgt tttctataga
       61 aagcttacat catcccgccc atcatacttg gatccattgc tggagctggg gctactggtt
      121 ctggtttatt ggctacgact gcttctgttg tcaaaatcaa gctggctaca gatgctgcat
      181 tttgtagggc tgaacgactc actttaactg gatcaatgat accttgatca atcatgttaa
      241 cccactcgcc agttgctgcg ttaaatccta taccaagctc agcatttttc aaacgatcga
      301 taacgataga tccttcaaat cctgcattgt gagcaatttg acgaacgggt tcttccaaag
      361 cacggagaac aatattacgt cctgttgctt catctcctgt caattccaag gtagcaacag
      421 ctggaatcac attggcaaga gctgttccac cgcctgcaac aataccttct tcaacagctg
      481 cacgagtagc gttgagggca tcttcaatgc ggagtttcat ttctttcaac tcagtttcag
      541 ttgcggctcc gaccttaata accgctacac cacctgacaa tttggccaag cgttcttgca
      601 atttttcacg gtcaaattca gaagttgtag tttcgatttg agacttgata accgcaacac
      661 ggtgagaaat cgcttcagga tttcctgcac cttctacaat aaccgtgcta tctttgtcca
      721 cggtcactct cgctgcttga ccaagagctt caattgtcgc atctttcaac tcaagaccaa
      781 ggtcttctgt gataactgtt ccgcctgtta agatggcgat atcttcaagc atggctttgc
      841 gacggtcacc aaaaccaggt gccttgactg ctactacgtt gaaggttcca cgaatcttgt
      901 tcaaaacaag agttggaaga gcctcgccat ccacatcatc cgcaataatc aagagtggac
      961 gattgctttg gagaatgctt tccaaaagtg gcaagatctc ttggatattg gaaattttct
     1021 tgtctgtaat caaaatgtac ggattttcaa ggtcagccac cattttttcg ctatctgtca
     1081 ccatgtactg tgaaaggtaa ccacggtcaa actgcattcc ttctacgact tcaagctctg
     1141 tttccatacc acgtgactct tcgatggtga tgacaccgtc tttgccaact ttttccattg
     1201 cttcagagat gtactcacca actttttcag aacgagaaga tacggctgca acttgagcga
     1261 tagcttcttt attggcaaca gggatggcgt tgtttttcaa agcttcaact gctgcggcaa
     1321 ctgctgtttc aatcccacga cgaataccga ttggatttgc acctgctgtg acgtttttga
     1381 ttccttcacg gacgatagct tgggtcaaga ctgttgcagt cgtagtcccg tcacctgcga
     1441 tatcattggt tttagaagct acttctgata ccaatttggc acccatattt tcaaaatggt
     1501 cttctaattc aatttctttg gcaatagtca caccgtcatt ggtaatcaat ggtgagccaa
     1561 atgatttttc aagaacgaca ttgcgacctt ttggtcccaa ggttacttta acagtatctg
     1621 caaggatatc gacaccacgg accatagctg aacgggcatc tgatgaaaat ttaatttctt
     1681 ttgacatact tactttctcc ttctattctt caatgattgc caagatgtta gcttcgccta
     1741 cgatgatata cttttcatcg ccatctttga catcaagacc tgcgtgggct tcaactaaga
     1801 cacggtctcc agttttaaca cttggagcaa ccaagtcacc gttcaaggta cgaacacctt
     1861 gtccagtagc cacaacttgg gctgttttgg ttttttcttg ggctgaacct gcgagaacaa
     1921 agcctccaac agtttgttct ttttcttcta cttttaagac caaacggtcc cctaatggtt
     1981 tcaacatctg atttcctcca taatgagata gatattatta gcactcttta tacctgagtg
     2041 ctaattcata gttctattgt atcacttagt cagaaataat caagaaaaaa gtctgacttt
     2101 ctcaagataa aaagcctgag accaactcag actttttaat tcttaaaatg gcaattcttc
     2161 ctcttccaag accaaatctg ccaaatcttg gcctgcatta ttttcacgca tagcacgttg
     2221 ggcacgactt tccaagagtt ggaatcctgt cacaaggact tcggttacat aattcatctg
     2281 accatttttc tcaaagcgac gggtacgcaa ttctccatca acggaaatga gactaccttt
     2341 ggttgcgtag cttgccaaag tttctgctag tctgccccat aggaccatat tgacaaaatc
     2401 aacttcacgt tcaccgtttt ggtctttgta acgacggttg acagcgatag ttgctcgcgc
     2461 tactgacttg tcattgttgg ttttgtgcaa ttctggtgta gacgttaaac gtccaatcaa
     2521 gataacttta ttatacatat tttcttcctc ctacttatct attcgtagga aatcaaaaaa
     2581 agttacagaa atttgtaact tttcgagaaa attttttatt ttttatgaac catgaaacct
     2641 gtcgcctgtt gattggccat aatggtcata tctgtaatct gaacacgacg aggttgacta
     2701 gtcacataga ctactgtatc tgcaatatcc tgagcttgca aagcttctat tccttggtaa
     2761 acggacgcag ctcgttcttt atcaccatga aaacgcactg tagaaaaatc tgtttcgaca
     2821 attccaggct gaatggttgt caccttgata tccgttgcga tggtatcaat tcgcagtcca
     2881 tccgaaaagg tcttaaccgc agccttggta gctgagtaaa cagcggcacc agcataggcg
     2941 tagattcctg cggttgaccc catattgata atatgacctt gattgacttt tatcattgct
     3001 ggcaagaaac agcgagtaac cgccatcaga cctttaacat tggtatccaa catggtcaac
     3061 atatccaact cctcatagtc ttgataggga gccaagtcaa gagccagtcc ggcgttgttg
     3121 accaagatat caatcctccc tatcgtttct agaatatcag agcaaacagt cttcaccatg
     3181 accatatccg tcacatctag tggaaaagtc cagacggttt gatttggaaa gcttactgca
     3241 aactccgact tgaggatttc taatctgtct atccgtcgtc ctgttagaac gacatcctca
     3301 ccctgctcca gataagcacg cgcaatcgct tcaccgattc ctgaggttgc tcccgtaatc
     3361 actacatttt ttgccatctt atttccttct atcagatgct gacaagttcc taggcagtcc
     3421 agtgtttcgc tgggtcgaac ggtgttccga caacttggtc ttctgataat tcaagcaccc
     3481 cacgtttttg cggagcattt ggtaaatgca attcacgagg actacacatc atcccaaaac
     3541 tcttttcacc acgaagttcg cctgggaaaa tgaaattccc ttttggcatc atggcaccag
     3601 gaagagccac aatggttttc aacccgacac gcgcattggg agctcctgca acgatttgta
     3661 ctgtcttgtc acttgcgact gcaacttggc agatgttgag gtggtcacta tctggatggg
     3721 ctaccatctc gacaatttca ccaacaacaa acttaggttc cttatcatta acaatttctt
     3781 ctgtaaaacc ttccgcctgt aattcttggt tcaaacgagc gacttgctca tctgataaaa
     3841 agacttgacc gcgctctgca atttcaaaca agctcgaaac ctcaaaaatg ttccaagcta
     3901 ctgtttcccc attttctttg aggaaaacac gggctacctt gcctttgcgt tccacattca
     3961 gtttggcatc tccgctattt ttcacgatga ccataaggac atcaccgaca tgttctttgt
     4021 tatacgtaaa aatcattgtt tcctttttct cctatttcaa tcctgctaaa aaatcgttaa
     4081 tttgctcctt acttttacgg tcgcgattga caaaacgacc gatttccttg tccttttcta
     4141 gaacaacaag gctaggaatt ccgtaaacat cccagagttt ggccaaatcc atatactgat
     4201 ctcggtccat tcgaataaag gtgaactctg gattggtctc ttcaatctct ggtaaggcag
     4261 gataaatata acgacaatcg ccacaccagt ctgccacaaa aaggaagacc ttcttgcccg
     4321 ctttttccac taaagatgct aattcttcta aacttgctgg ctgtatcata agacttcctc
     4381 ctcatagact aggtcttcat tttcatagac aaaggtataa tgacgaccat cctcaaaaat
     4441 gacgccacca accaagctct ccagactgct ttcgtaaact tgaacataga gggtcgcaat
     4501 ttcccccatg tcggaaaaat ggtctcgcac aatctctgtc aactcttcct gagtcttcat
     4561 gagcttacgg tcatctgcaa cttttttcgt ggcaagagca aggcttccga tacctagcag
     4621 agccaagcct gccatccaca tttttttagc tttcatacca ttcattttaa cacaaaaaag
     4681 gcttcaggac aaatgaggaa gcagcagaaa agcaagtaaa aagcctcttc ctttaaggaa
     4741 aaggacttct tatactcaat gaaaatcaaa gaccaaacta ggaagctagc cgcaggctgc
     4801 tcaaagcact gctttgaggt tgtagataga actgacgaag tcagctcaaa acactgtttt
     4861 gaggttgtgg atgaagctga cgtggtttga agagattttc aaagagtatt attcttattg
     4921 ccaggcacct aagttgccaa cgtagtaacc atcaggtgtg taggtattgc gaagcatctt
     4981 acctgatgaa gccagataat actacttgcc attgtctttg acccaatcat tcgcaatcat
     5041 ggaaccagaa gaacttacat aataccattc tcccttgtca taaacccaag tactgacttt
     5101 catggttcct gagcaattaa aggcaaaaaa actgtccaat atcattcgtt ttttaaaagc
     5161 atttgacact acatcatcta cgctgtagta catagataca tcaaacgtaa aagccaaaat
     5221 atcgaaaaat atacaacttt taaaggcagc atttcatttt ttaaagtcta acaaccatag
     5281 aactgaaatc agagcaaggc atcaatttcc tactcttagt acgtctattt tgatggttga
     5341 agtgaagatt tttttattta acgtagacaa tttccaactt cccaaaagcc acatctccac
     5401 ggatagtcaa ggttttgctg gttggggcta caggagcgtc agccttagct gcaccaaagg
     5461 aggtttctac tttcaaatct acacgccagt gttgtggaac atagacggtt gcatttccga
     5521 aggccacttc aatatttaaa gttgcaaaat cacctagcat ctctgcatta tcatagtaga
     5581 ttttagcatc cccaaaagcg acttccactt ggtcatctac gagatcttga tcttgcttat
     5641 agaaggtccc gctaccaaaa gcgacttcct tatccgtgac gactgttttt ttcccattgt
     5701 accaccattt tttttcattc cagaacttac ttgaatgcgt cagataacca acaccaagta
     5761 ccaccaagat gctagcccaa ataagagaat gattggtaac tggtaacaag tcataagcgt
     5821 aatttgcaat gatgatcgcc agtaaacctg taaaaactgc cgaagtgaga tgacgtctaa
     5881 ggatggactc aatggactta taagcaaaaa aaacaatacc tagtaaaggc catattttac
     5941 catccaaaga aggaattcca aaattccctt gcagcaagat ccaagctgct aaaaccaata
     6001 aaacaatacc aaatgctttc tttttcatgt tttttacctc atgtttctta gattttcttt
     6061 taggagggat tggtaatgcc gtgacacatg aacctccttg tgggtttgat aaaaggaaat
     6121 ggtgcccgtt cctgaaaagg acttgtccac cgaatagatt tgccgaatat taacgatcgt
     6181 tgacttggat actcgactaa aatagcgagg aaggatagcc tccaactcat agagcttgag
     6241 gcgaacctca taagcttcct tctggttatg agcgtagatc ttgctccctt ctgtttcaaa
     6301 gaagagaatt tctgacaggt ctagataata ttcacctgtc cccttgtaaa aagtcaacct
     6361 cggagccttt gactcttgca agagccgttg caagtctgca atttcatctg tcaaagtggg
     6421 ggtcttgatg acaatttcag tctcctctaa attgccgtca atctcaattc gtaacttcat
     6481 cacatctcct ttctgactct actatatcaa agctaagtta ggaatacaag ggcaaaaaag
     6541 caagtggtca atttgaagca gtaagtggtt gtaggactag cttaacttac atgtcagaat
     6601 aggaagaaaa ggaatcccca caccaaacca caagcatagc caaccaagac atccttggga
     6661 taatgaacac cccctaaaac cctcaccaac cccagcaaag ctgaaaagat caagcatact
     6721 aagccaatag gtagactagc atgcagacag gccatggaga tgatagttgc cgaaaagaca
     6781 tggcgactgg gcatcgaccg tcccgaacta tccttatcaa gaaggggaca gatattccaa
     6841 gtttcataag gtctcgggtg attgattttc ttacgaaaca gggacaaggc cacaaaacct
     6901 gatgcaggaa taagcacata aaccccaact tgctgaccaa gtcctagttg caggtaagtg
     6961 gtgactagca agatcagata gaccaggggc atggcgactg tcatcaaacg attgaaactg
     7021 cgtaatagga ataaaagaat tggacgacta gttagtctgg atctgatatt tcgataccat
     7081 tcttgataat ttttcattta tgcttctcat acttttctag aacttgttga gatgttttcc
     7141 ccttggcaag ccaatccact agcttgtcca agcgacgtat ttcctgcatc agaggatcat
     7201 caatttcctc aatacggaca ccgcaaatct tccctgtaat tgcaattcgt tcagggacat
     7261 aatatggtgc ttgtcgaaaa aaatctccgt aagtaacatc cctatccaga caagcaagaa
     7321 cgtcactcac ttcataccct gtcaaccaac tggtcacttg gtgaactgac tctgcctttc
     7381 caccctttcg ctcaactttt gcaatcaagg ctaagtagac agcagcaaat ttcatattgt
     7441 ataatttctg actcatactt ctctctttct atgtgtacta gtataaataa gaaaaagaag
     7501 gtcgtcaagc cttcttttga tttattcttc tgcttcatct tctgtaaatt gactattgta
     7561 caagtcagcg tagaagccac cttgcgccat cagttcctca tagttgcctt gctcgatgat
     7621 atttccatct ttcatgacca agatcaagtc tgcatttcgg atggttgaca agcggtgggc
     7681 aatgacaaag gatgtgcgtc cttccatcaa acggtccatg gctttttgga tcaattcctc
     7741 tgtccgtgtg tcaacagaag aagtcgcctc atccaaaatc aaaagcggtg catccttaag
     7801 aagggcacga gcaatagtca atagttgttt ttgtcttaca gacaaggtca cggtgtcatc
     7861 caagatggta tcatagccat ctggcaaggt cataataaag tggtgaattc ccacagcctt
     7921 actagcttcc atcattcgtt catcactaat ccctatttga ttatagatga gattgtctcg
     7981 aatagttcct tcaaagagcc aagtatcctg caagaccatt gaaaaggcat catgcacttc
     8041 tgaacgcgtc atagccttgg tatccacacc atcaatgcga atacttccct tatcaatctc
     8101 atagaatttc atcaaaagat tgacaatggt tgtcttacca gccccagtcg gcccaacaat
     8161 ggcaaccttt tgaccagcat gagctgtcgc agagaagtca tagtcttgaa cattgacacc
     8221 gtccaccaga atttctcctg ctgacacgtc gtagaaacgt ggaatcagat tgaccagagt
     8281 tgatttacca gaacctgttg acccaataaa ggccactgtt tgaccagttt ctgctttaaa
     8341 gctaacatgt tcaataactg cctccgaatt tgccgcatag cggaaggtca catccttaaa
     8401 ctcgacctga cctttgaagt tttcatcagt cagctgcact tgaacagggt tttggataga
     8461 agaatgcaaa tctaaaactt gattaatccg cttagcagag accatagttc ggggaagaac
     8521 gatgaagagt gctcccatga gaaggaagcc catgacaacc tacatggcat aagacatgaa
     8581 aacaatcatg tcactaaaga gaggcagacg cgctatcgga gcagcgtcgt taatcacata
     8641 ggccccaatc cagtaaatcg ccacactcaa accacttgaa atccccatca tgataggatt
     8701 caaaatagcc ataagacggt tgacaaacaa attcaaacgg gtcaattcat catttactgc
     8761 tgcaaatttt tcattttgat aatcctctgc attgtaggca cgaacgacac gaatacctgt
     8821 taaactctca cgagtgatac tgttcagttt atctgtcagt ccctgaatca aggactgttt
     8881 tggaaaggct agcgtcatca aaacggtcgt catcaggacg ttgataatca ctgccacaag
     8941 tacggcccag agccagtatt ctgaatgacc taaaatcttc ccaatagccc agatagccat
     9001 aattgaacca cgcgttacca cttgcaagcc catagtaatc aacatttgaa cttgagtaat
     9061 gtcattggta gtacgcgtca agaggctagg aattgaaaat ttcttaatct ctgtctgcga
     9121 gtaatccaaa actcggttaa aaatatcact tctcagccta ctagtataag aagccgccac
     9181 tcgggatgca aaaaatccaa ctgcaactac ggacaagaag gcaagaaagg acattcccat
     9241 catcatgctt gccgactgcc acaactcatc taaattagtt tcttgactac ctagcaaatc
     9301 cgtaattttc gagatatagg tcggcacttc caactctaga tagaccgaaa agcaagtaaa
     9361 gagaatggct agtaaaatca tcccccattc ttttctacta attcttttgg ctaatttctt
     9421 tattctctcc tcctattccc ttgatatttt gcctgtagtt gaccgagaac cttctcaaaa
     9481 atcagtaatt catcttcatc aatgtcttcc atcaactgct tgtctatgcg ttcaaaaaaa
     9541 gccttaacct gttgcatctg agaacgtgct ttgtccgtca gacgaacaaa cttagcccgc
     9601 ttatcaacag gactcgcctc caattccacc aaaccatttt gcactatacg cttaaccaga
     9661 ttactagcaa caggcttggt aatattgagt tcctgctcga tatctttaat caagaccaag
     9721 tcttggtttt tctcgcgatt atccaaaaaa cgcacaacct gaccttgcgg cccacccata
     9781 aattcaatgc cgcaacgttt ggcttccttt tgcaccatca ggtgaatttg atgaccaaaa
     9841 cgcttaaaga ctaacatcgg tttatccata atctccccct tctaaataaa aatagttctc
     9901 tggagaataa ttaaatttct atgagaacta ttttcttgat taaaaaaatc ccaagtgatt
     9961 ttctcactta ggatcatgtt ctataggtta aattaaaacc catctacgtt cgtataaatc
    10021 ttttggacgt cttcgtcgtc ttcaagaacg ctgtaaagtt tttcaaaggt ttcaaggtct
    10081 tcgcctgaca attccacttc tgactgagga atcatttcca attcagtcac ttggaattct
    10141 tcaataccag actcacggag agcaacgata gccttgtgaa ggtcagttgg cgctgtgtaa
    10201 actgtgattg taccttcttg tgcttctacg tcatccacat ccacatccgc ttcgagcaat
    10261 tgctcaaaga ctgcgtccgc atcttcacct ccaaatacaa taacaccttt gttgtcaaaa
    10321 aggtaagaaa cagaacctga agcgcccatg tttccgccgt ttttaccaaa ggctgcacgg
    10381 acattggctg ctgtacggtt aacgttagaa gtcaaagtat ccacaattag catagagcca
    10441 tttggcccaa aaccttcgta acgtccttct gtaaaggttt cgtctgtgtt tcctttggct
    10501 ttatcaatcg ctttatcgat aatgtgtttt ggcacttggg cttgtttagc acggtcgata
    10561 acgaatttca aagctgagtt tgattctgga tctggatcac cttttttagc tgctacatag
    10621 atttctacac caaattttgc atatacttta gagttggctc catctttagc cgttttcttg
    10681 gctacgatat tggcccattt acgtcccatt aggaatctcc ttttttcaca ttttaatctt
    10741 tcttattata acacaagttt ttttgatttt cactagagga aatggatttt attagcaaat
    10801 caagctagga tagcacttta cctgctaaga tggtcttacc tttctatctt tatcaacaga
    10861 cactcatcca cattcaaaaa acaaactaga ccattatctg caaatagaaa gtttcagcca
    10921 agtttgacaa agtcagctca aattactgtt tgaagtttgt agatataagc gacaaaaaca
    10981 atcatactgc accttttgtt gacagtctac tccagacata tcatagttca agtaaatact
    11041 ttgaaatcca acagttctta taggcgctat tgtattccaa gaaatcaata gaagagtttc
    11101 taagcaaacc tctaatactc aataaaaatc aaaaagcaaa ctagaaagct agccgcaggt
    11161 tgctcaaaac actgttttga ggttgcggat agggctgacc tggtttgaag agattttcga
    11221 agagtataat ttacgtgttc ccaagatgga gaaattagac tagtacactg gcacttctaa
    11281 accattgcta gcaattgatt tgttcatatt taatttcatt ttttccataa atgggtatta
    11341 gatataaaca gcaaaatatt tccgatacgt gtcattcttg aatttccaat catctaaaac
    11401 aagtaaagga taatcaatcc cctgtatatc aaggaattgg ctaccctttt tactttttta
    11461 cacattctgt ttgatagatt cattttaaca tcacgagcat actccaatgg aaatcgctag
    11521 gcaagagata aactttcaga tatccgcaga gagatcatcg cctctttttg tcgcaagcat
    11581 tctcctctcc tagtcatttt ctaccttatc ttctacctga ggatagagag ttgttcccca
    11641 aatagaaatc gtccgcttac gcactagtgg caaatcggtt ttttcataaa ccgtacgcca
    11701 ccattcccag gcaagcccgg tacactctct aattttgaca gagagattac gaacattccc
    11761 ttttaaagga atactagtgg taaagtgagc cgtcaaatcc tgcccatttc tgtcccaagc
    11821 cttaggagtc aagacttcct taccttgatg atcataggat aattcatccc aagtaatata
    11881 atattgggca acataggcac cactatgatc cagcagtaaa tctccgtttc tgtaagctgt
    11941 aaccttagtc tcaacatagt ctgtactgtt ttgaaaggtc gcaactacat tgtcacgtaa
    12001 aaaagaagtt gtataggaaa tcggcaagcc tggatgatct gctgtaaagc gactgccttc
    12061 ttgaatcaag tcctctacca tatccacctt gcctgttaca actcgggcac ccgaacttgg
    12121 gtcgccccct aaaataaccg ccttcacttc tgtattgtcc aaaatctgct tccactctgt
    12181 ctgaggagct accttgactc cttttatcaa agcttcaaaa gcagcctcta cttcatcact
    12241 cttactcgtg gtttccaact tgagatagac ttggcgccca taagcaacac tcgaaatata
    12301 gaccaaagga cgctctgcag aaattcctct ctgttttaaa tcctctaccg ttacagtatc
    12361 ttgaaacaca tctcctggat ttttaacagc atctacgctg actgtataat aaatctgctt
    12421 aaaattaaca atctgaatct gcttttcgcc tgaatggaca gagttaaaat caatatcaag
    12481 agaattccct gtcttttcaa agtcagaacc aaacttgacc ttgagttgtt ccatgctgtg
    12541 agccgtgatt ttttcatact gcattctagc tgggacatta ttgacctgac cataatcttg
    12601 atgccactta gccaacaaat cgtttaccgc tccgcgaaca cttgaattgc tggggtcttc
    12661 cacttggaga aagctatcgc tacttgccaa accaggcaaa tcaatactat aagtcatcgg
    12721 agcacgatcg accgcaagaa gagtgggatt attctctaac aaggtctcat ccactacgag
    12781 aagtgctcca ggatagaggc gactgtcgtt ggtagctgtt acagaaatat cacttgtatt
    12841 tgtcgacaag ctccgcttct ttctttcgat aacaacaaac tcatcgggta gctgattacc
    12901 ctctttgatg aaacgatttt caatactttc tccctgatgg gtcaagagtt tctttttatc
    12961 gtaattcata gctagtataa agtcatttac tgctttattt gccatcttct acctcctaat
    13021 aagttcctgg attgagttgc ataaactcag acttgttcag cgaaatcagc cgtggttgga
    13081 ctaagtaatc caaaatttcc tcgtacaatt cttctgagac attgcgtcgc cgtctggcta
    13141 gataagaagt cggaatgacc gtattatcca acataaatac cttatctaag tcaatcaagg
    13201 ttggtcttgt aaaaggatta cgagctagat ccggctcttc tatcataaag ttcttgacca
    13261 aacgtctggt caagagagct ggtttgaagg tctgattttt aaccaactct ttgtttttag
    13321 tcatgctgtt gtcaatacag atatacatat gattcttcac agccaaatcg ctactaatag
    13381 tcggaaaagg caaataaaga gctacaacat ctcctctctt aatcaagcaa gagcaccccc
    13441 ttttctccta atgtaacata gacaggattg accaagtctt ctgattgact cagaatttcc
    13501 aaagtttgag tttggcgcgc tgtcaattta gtagcatctt gtctcttcaa tacaaaatgc
    13561 ttgtcgccaa taaccttgac aatataatcc ttctccaaag ctgactggta aatccacatc
    13621 agatgttgtc tgtcctgaga actcaagaga gaaggatttt caagcctccc gatagtctga
    13681 taaaaatcaa aaacaggagc taactcctgc caatctgatt ggctagttgt caaggctaga
    13741 aaaagggctt tgcgagctga tacttcttgg ttagccttga gagttacttt cccctccaag
    13801 ttttttagaa atcgggaaac tccagaaagc aaatttttct ctaactgcga gaaataaaaa
    13861 cctttcgttc ccagacataa gtctttcatg tcgctttctc tagcaaataa gagctcaaac
    13921 atttgatagt aaaagaaaaa tatctggcac tgggccgcgc tcatcttttc cttatcggct
    13981 tcttttttta accagagcaa gggcgacagg tagctggatt gagacatttc ctctacctcc
    14041 tactcttttt taactggagc atctgcacta gctgccactt cttttgactg gatactttcc
    14101 cactggttaa tctcctctga gataagacct tcgcatgtct tgacaaatag ggcaaaagcc
    14161 ttggtctttc ctgcatattt ctccgtttgg cattgataga ggaatttttc tttctccagg
    14221 agttgcgcag ttttttggta agaaatccaa ttttcctttg cattatacaa attgataatc
    14281 ccctcacaca gcaagccgag actggataag gcaaccgaaa tcaaacggta gcgatcacct
    14341 ggcataggaa tagcacaaaa gacagctatg aggaaacctg ccacgatttc tgttattttt
    14401 aataccttat agcgcctacg atgttgaacg cttttcttta aaaaatgagc tatctgtacg
    14461 tctaatcgct ctgtcaggta catttcttct ggcgtcatat tcgtaactcc tttcatttac
    14521 tttgataatc atagtataac atatttgaat atcaaagtat agtaaaaact ggactataac
    14581 ttattagact tcctgcgaaa caaaatatgg tatagtagtt ctatgaatta tgaagcaagt
    14641 aaacaattaa ctgatacacg atttaagcgt cttgttggtg ttcagcgtac cacttttgaa
    14701 gagatgttag ctggattaaa aacagcttat caaaaaagtc ggacaagctg gtaaaatctt
    14761 ggctgacagt aattatcaag ggctcatgaa gatatatcct caagcacaaa ctccacgtaa
    14821 atccagcaaa ctcaagccac taacagttga agataaagtc tataaccatg cgctatctaa
    14881 ggagagaagc aaggttgaga acatctttgc caaagtaaaa acgtttaaaa tgttttcaac
    14941 aacctgtcga aatcatcgta aacgcttcgg attacgaatg aatttgagtg ctggtattat
    15001 caatcatgaa ctaggattct agttttgcag gaagtctatt atatatatgc acagacatat
    15061 gaaatctttt tgatacagcc ttctttttac atagagagac agcagttatg atatatttat
    15121 ccattcacaa catcttctgt accaatacta caataattgg tacattttga ttacacaatc
    15181 gtttcaaaaa atatgatgga agactgagta ttttatagta attcccttcc tatcaactag
    15241 atcaaccagt tgagtgttga atgttgaaac accctagcct cagcaaagga ctatgatcag
    15301 catttcctag ccaataggac gctccaaatc acctattcta agtccatcac tagcttggtc
    15361 agtaagatac agactgcaag gcgagactga tgtggttgat gagattttgg aagagtatta
    15421 caatcataga tccaccagta gacttgaccg cagatttaac tatagtagat tgaaactaga
    15481 atagtacacc tctgcttcta aaacattgtt agaaatcgat ttgactgtcc tgatcaattt
    15541 gtcctgttct cgtttcattt tactatacta aaaaaccacc tgaaacaaat caagtgacta
    15601 gaggataaaa acgaagactg ggcaaaaagt tttgaaaagc aaaaaacgca taatatcagg
    15661 tcttgaaaaa ccttgatact atacgtttga ttgtgggaag attgacttca ttttctcctg
    15721 aaattgaagt tttttctagt ttccagatat agacgaattc aatatagcca tctcgctaca
    15781 attattttaa ccatcgagaa aatttttcag aatttcaaaa atttcatttt gatccaatga
    15841 aatgtcatca ttttgaagaa tagttgactt cacaggctct aattctatca caaagcggtg
    15901 catgtctgct tttaccgcac tacttgatgt tatagccgat aacttttcat ctcctagcaa
    15961 ggaagctgtc aaacgggtaa ggtcattcaa atgcttttta atggacttac ttaaaccttg
    16021 agcacctgtg gcagagcgct ccctcatatc cagccaagct ttagccttaa aaataattaa
    16081 tactcaatga aaatcaaaga gcaaactagg aagctagctg caggctgctc aaaacactgt
    16141 tttgaggttg tagatggaag ctgacgtggt ttg
//
LOCUS       DAVLZS010000041        15986 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLZS010000041 DAVLZS010000000
VERSION     DAVLZS010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15986
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.041"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            56..376
                     /locus_tag="VYO88_001519"
     CDS             56..376
                     /locus_tag="VYO88_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1719597.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            422..730
                     /locus_tag="VYO88_001520"
     CDS             422..730
                     /locus_tag="VYO88_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1719598.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            747..2045
                     /locus_tag="VYO88_001521"
     CDS             747..2045
                     /locus_tag="VYO88_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1719599.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            2196..4634
                     /locus_tag="VYO88_001522"
     CDS             2196..4634
                     /locus_tag="VYO88_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1719600.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            4653..5321
                     /locus_tag="VYO88_001523"
     CDS             4653..5321
                     /locus_tag="VYO88_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1719601.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILVASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            5339..6427
                     /locus_tag="VYO88_001524"
     CDS             5339..6427
                     /locus_tag="VYO88_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1719602.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            6882..9383
                     /locus_tag="VYO88_001525"
     CDS             6882..9383
                     /locus_tag="VYO88_001525"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1719603.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTS
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDTITSPEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGDVKEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            9522..10364
                     /locus_tag="VYO88_001526"
     CDS             9522..10364
                     /locus_tag="VYO88_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719604.1"
                     /translation="MNRLVNDSRKCEILLFKISIIVVSVIVLVMSIVGAYYFKNCLWD
                     KESLNLTLTLDTLFAVFITFFSFSNDKSSNIFGISPNEIIRTQSEVYQFLFTKSFATL
                     LIVTNLLSIIHYFGAKNLIVSFNETYPRIQSSVGIMWLPLFGILIIYFIWLLIEGLKY
                     IRKINYIIQNREIIYFYSQVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNFLQN
                     SDDKRGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEIDKKL
                     EISR"
     gene            10420..11115
                     /locus_tag="VYO88_001527"
     CDS             10420..11115
                     /locus_tag="VYO88_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719605.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            11127..11543
                     /locus_tag="VYO88_001528"
     CDS             11127..11543
                     /locus_tag="VYO88_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719606.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(12170..12262)
                     /locus_tag="VYO88_001529"
     CDS             complement(12170..12262)
                     /locus_tag="VYO88_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1719607.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            12423..13394
                     /gene="ruvB"
                     /locus_tag="VYO88_001530"
     CDS             12423..13394
                     /gene="ruvB"
                     /locus_tag="VYO88_001530"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1719608.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            13375..13947
                     /locus_tag="VYO88_001531"
     CDS             13375..13947
                     /locus_tag="VYO88_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1719609.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLKKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            14178..14936
                     /locus_tag="VYO88_001532"
     CDS             14178..14936
                     /locus_tag="VYO88_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1719610.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            14945..15748
                     /locus_tag="VYO88_001533"
     CDS             14945..15748
                     /locus_tag="VYO88_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1719611.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIVAMLAMHE
                     LLKMRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            15770..>15986
                     /locus_tag="VYO88_001534"
     CDS             15770..>15986
                     /locus_tag="VYO88_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1719612.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWG"
BASE COUNT         4866 a         2648 c         3510 g         4962 t
ORIGIN      
        1 attttaaaat ttcaaatgaa aaaagctttt tacatagtga aatgaggagg aatttatgga
       61 aattattgtt ccagatcaaa ttatcatggg tttaatttta tatgctggtg atgcgaaaca
      121 acatatttat aaagcgttag attacataaa aaatggtaca tgtgaacggt gtgaagaaga
      181 aatccagtta gctgatgccg ccttattaga agctcataat ctacaaacaa aatttttggc
      241 acaggaagcg tctggtacaa agacagaaat tacagctctc tttgttcatt cacaagatca
      301 tctcatgact agtatgacgg agattaattt aatcaaagaa attattagtt tgagaaaaga
      361 acttcataaa aaataatact agagtattat cattgttatt aacatagagg aggaaaacat
      421 aatggtgaag attggtttgt tttgtgcagc aggtttttct actggtatgc ttgtaaataa
      481 tatgaaaatt gcagcgcaag ctagtggagt tgaggcagaa atagaggcgt tttctcagtc
      541 taaattagcg gattatgcgc caaatataga tgttgcacta ttgggtccac aagttgctta
      601 tacattagat aaatcaaaag aaatttgtga taagtgtgat gttccgatag ctgttattcc
      661 gatgatggac tatggtatgt tagatgggaa aaaagtatta gatttggccc tatctttgat
      721 tagtgggtaa gaaaaggaga tttattatgt caaagatgga tgttcagaaa atcattgcac
      781 cgatgatgaa gtttgtgaat atgcgtggca ttatagctct aaaagatggg atgttagcaa
      841 ttttgccatt gacagtagtt ggtagtttgt tcttgattat gggacaattg ccgttcgaag
      901 gattaaataa gagcattgct agtgtttttg gagctaattg gacagagccg tttatgcaag
      961 tatattcagg aacttttgct attatgggtc taatttcttg tttttcaatt gcctattctt
     1021 atgctaagaa tagcggagta gaggctttac cagctggagt tctatctgta tctgcattct
     1081 ttattttgct aagatcatct tatatcccta aacaaggtga ggcgattggg gacgctatta
     1141 gtaaagtttg gtttggaggc caaggaatta tcggtgctat cattataggt ttggtagtag
     1201 gaagtattta taccttcttt ataaagagaa aaattgttat taagatgcca gaacaagttc
     1261 cacaagctat tgccaaacag tttgaagcaa tgattccagc atttgtaatt ttcttatctt
     1321 ctatgattgt atatatttta gcgaagtcat tgactaatgg cggaacattc atagaaatga
     1381 tttattctgc tattcaagtt ccgttgcaag gtttaactgg atctttgtat ggtgctattg
     1441 gaattgcatt ctttatatca tttttgtggt ggtttggtgt tcatgggcaa tcggtagtaa
     1501 atggagtagt gacagctctg cttttatcta atcttgacgc taataaagct atgttagcct
     1561 ctgctaatct atcattagaa aatggtgcac atattgttac tcaacaattt ttagattcat
     1621 ttttaattct atcaggttca gggattacgt ttggtcttgt agttgccatg ctttttgcag
     1681 caaaatcaaa acaataccaa gccttaggaa aagttgcagc ttttccagca atatttaacg
     1741 taaatgagcc agttgtattt ggatttccga ttgtcatgaa tccagttatg tttgtacctt
     1801 tcattcttgt tcctgtactt gcagctgtga tagtatatgg agctattgca acaggtttca
     1861 tgcagccatt ctcaggggta acattgcctt ggagtacacc agctattcta tcaggatttt
     1921 tggtgggtgg atggcaaggt gttgtgactc agttattagt attggtgata tctacagtgg
     1981 tttactttcc attctttaag atacaagatc gtttagctta ccaaaatgaa atcaaacaat
     2041 cttagaggta tttgtgtgtt actgttaaac tcacacattt gtgctaaaaa ttagagagtt
     2101 aaaatttttc tagttaaaag cttgaaaatt tctataaaaa tcggtattat attttcgaaa
     2161 gaaataaaaa tattttcgaa agaaaggtgc ttacgatggt aaatacagaa gtagcaagaa
     2221 caacaatcaa gacagaatat tttggaagcc ttactgaaag gatgaacaaa tatcgagaag
     2281 atgttttaaa taaaaaacct tatattgatg ctgagagagc agttctagca acacgcgcct
     2341 atgaacgata caaggaacaa cctaatgtcc taaaacgtgc atatatgctg aaagaaattt
     2401 tggaaaatat gtctatctat attgaagaag aatctatgat tgcgggaaat caagcttctt
     2461 ccaataaaga tgctcctatt tttccggaat atacgctaga atttgttctc aatgagttgg
     2521 atctttttga aaagcgtgat ggagatgttt tctatattac agaagaaaca aaagaacaac
     2581 ttagaagtat tgctccgttt tgggaaaata ataatttacg tgctagagct ggtgccttat
     2641 tacctgaaga agtgtcagtt tatatggaaa caggattctt cggtatggaa ggtaagatga
     2701 attctggaga tgctcactta gcagttaact atcagaaact tttgcaattt ggtttaagag
     2761 gttttgaaga gcgggctcgt aaagcaaaag tagctctaga tttaacagat ccagcaagta
     2821 ttgataaata tcatttttac gactctatat ttatcgtaat cgatgctatt aaagtatatg
     2881 caaagcgctt tgttgctctt gctaaaagtt tagccgaaaa tgcaaatcct aaacgtaaga
     2941 aagaattact tgagattgca gatatttgct ctagagtccc atatgaaccg gcaactactt
     3001 ttgcagaagc tattcaatca gtttggttta ttcaatgtat tttacaaatt gaatctaatg
     3061 gccactctct ttcatatggc cgttttgatc aatatatgta tccatatatg aaggctgatt
     3121 tagaaagtgg taaagaaaca gaagatagca ttgttgaacg tctgacaaat ctttggatta
     3181 agacaattac aattaataag gttcgcagtc aatcacatac attttcttca gcaggaagtc
     3241 ctttatatca aaatgttaca attggtggac agactcgaga taagaaggat gctgttaacc
     3301 cattatctta tttggtatta aaatcagttg cacaaaccca tctaccgcaa cctaatctaa
     3361 ctgtacgtta ccatgcaggt ttagatgctc gtttcatgaa tgagtgtatt gaagtgatga
     3421 aacttggttt tggtatgcct gcatttaata atgatgagat tattattcct tcttttattg
     3481 caaaaggagt attggaagat gatgcttatg attacagtgc cattggatgt gttgaaacgg
     3541 cagttccagg gaaatggggc tatcgttgca caggtatgag ttatatgaac ttccctaagg
     3601 ttctacttat cacgatgaat gatggaattg atccggcttc gggtaaacgg tttgcaccaa
     3661 gctttggtca ttttaaggat atgaagaact tttctgaatt agaaaatgct tgggataaaa
     3721 cactaagata tttgacacga atgagtgtta ttgttgaaaa ttctattgat ttatcattgg
     3781 aacgagaagt tcctgatatt ctatgttcag cattgactga tgattgtatt ggtcgtggaa
     3841 aacaccttaa agaaggtgga gcagtatatg attatatatc aggattgcaa gttggaattg
     3901 caaatttgtc ggattcatta gctgcaatta aaaaattggt gtttgaggaa gaacgtataa
     3961 gcccaagtca gctttggcat gcactggaaa cagattatgc cggagaagaa ggtaaggtca
     4021 ttcaagaaat gttgattcat gatgcaccta agtatggtaa tgatgatgat tatgctgaca
     4081 aattggttac tgctgcttat gacatttatg ttgatgaaat tgctaaatat cctaatacac
     4141 gttatggaag aggtccaatt ggaggaattc gttattcagg aacatcttct atctcagcca
     4201 acgtagggca gggacgtgga acattagcaa ctccagatgg acgcaacgcg ggtacaccgt
     4261 tagcagaggg ttgttcacca tcacataata tggatcaaca cggccctaca tctgttttaa
     4321 aatctgtttc aaaattacca acagatgaaa tcgtaggtgg ggttctctta aatcagaaag
     4381 taaatcctca aacgttagcc aaagaagaag ataaattaaa actaattgct ttgttacgaa
     4441 cattctttaa tcgtttacat gggtaccata ttcaatacaa tgttgtttcc agagagacgc
     4501 tgattgacgc tcagaaacat cctgaaaaac acagagactt aattgttcgt gttgcaggat
     4561 actctgcatt cttcaatgtt ctttctaagg caacccaaga tgacattata ggacgtactg
     4621 agcatacttt gtaaaataaa gaggttcttt ttatggaatt tatgcttgac acattaaatt
     4681 tagatgagat taaaaagtgg tctgaaattt tgccgctagc tggggtaact tcaaatccca
     4741 ctattgcaaa aagagagggt tctattaatt tttttgaacg aatcaaagat gtaagagaat
     4801 tgattggctc tacaccctct attcatgttc aggtgatttc tcaagatttt gaaggcatct
     4861 taaaggatgc tcatgaaatt cgaagacaag caggagatga tatatttatc aaagtacctg
     4921 ttactccagc tggattacgt gcaataaagg tgctaaaaaa agagggctac catatcactg
     4981 caacagctat ttatacagtt attcagggat tattagctat cgaagcagga gctgattacc
     5041 tagctccata ttataataga atggaaaatc tgaacattga ttcaaattct gtcattcgtc
     5101 aattagctct tgctattgat agacagaact ctcctagtaa gattttagtt gcatccttta
     5161 aaaatgtagc acaagtaaat aatgctttag ctgcaggtgc gcatgctgtt acagcaggag
     5221 cagatgtttt tgaatcagct ttcgccatgc catctatcca aaaggcggtt gatgattttt
     5281 ctgacgattg gtttgttact caaaatagtc gttccattta gatagagagg aaatatatat
     5341 gagaattttt gctagtcctt ctagatatat tcagggggaa aatgccttgt ttgaaaatgc
     5401 caaatcaatt ttggatttgg gaaattaccc tattctatta tgcgatcagt tggtttatga
     5461 tattgttgga aaacgatttg aagattacct acataggtat ggtttccata ttgttctggc
     5521 gctatttaat ggtgaagctt ctgacaatga aatcaatcga gttgttgcct tggctgagaa
     5581 agaaaattgt gatagtatta tcggtcttgg tgggggaaag acgattgata gcgcaaaagc
     5641 tattgcagat ttgattgaaa agcctgttat tattgctcca acaattgcat cgaccgacgc
     5701 acctgtatct gctttatctg ttatttatac agatgaaggt gcatttgatc attatctatt
     5761 ttattctaaa aatccagatt tagttttggt tgatacaaaa gttatttcac aagcccctaa
     5821 gcgtttatta gcgtctggta ttgcagatgg tttagcaact tgggttgagg cgcgtgcggt
     5881 tatgcaggca aatggaaaaa ctatgttggg acaacagcaa acattggctg gagttgcaat
     5941 tgcgaagaaa tgtgaagaaa cgctgtttgc agatggttta caggctatgg cagcttgtga
     6001 agctaaagtg gtgacaccag cattagaaaa tattgttgaa gctaatactt tattgagtgg
     6061 tctaggtttt gaaagtggag gattagctgc ggcgcatgca attcataatg gttttactgc
     6121 attgacaggt gacattcatc atttaacaca tggtgaaaaa gtagcttatg gaactttagt
     6181 acaactatta ttggaaaata gacctaaaga agaacttgat aagtatattg agttttacaa
     6241 aaaaattggt atgccaacaa ctctaaaaga aatgcatttg gatcaagttg gatatgatga
     6301 tttaataaaa gttggtaaac aagcaactat ggagggtgag acaattcatc agatgccgtt
     6361 taagatttcg ccttcagatg ttgctcaagc tattatcgct gtagatgcct atgtaaattc
     6421 aaaataaaca ataaggacta ctgttttcca aatggtagtc ttttattgat ccccgtattg
     6481 aattctatag aagattgaaa taggatgaga acaaatcgat tgggaaagta aaattaattt
     6541 ctataaatgt tttagcaatt gtttcgtact atttcagatt cagtctacta tacgttcttc
     6601 ataaatcaaa aagcgacata ggttgtcggc tatttattgt gaatacatta attagcattc
     6661 cagttttatc ttcggtctaa aataagtatt ttgtgctata cgagataagc gtcttgactt
     6721 actccttgat ttactgcata acaatgggat aaaaagtggg agatagagca attcatagtc
     6781 atcaaaatta atgagataca gtatacagtt ttttctttaa acacatttca aattccctca
     6841 aaaatggtat aatagtaaca tcacaaaatt ggagagagac catgagtttt tataatcata
     6901 aagaaattga gcctaagtgg cagggctact gggcagaaca tcatacattt aagacaggaa
     6961 cagatgcatc aaaacctaag ttttatgcgc ttgatatgtt cccttatccg tctggagctg
     7021 gtctgcacgt aggacaccca gaaggttata ctgcaaccga tatcctcagt cgttacaaac
     7081 gtgcgcaagg ctacaatgtc cttcacccaa tgggctggga tgcttttggt ttgcctgcag
     7141 agcaatacgc tatggatact ggtaatgacc cagcagaatt tacatcggaa aacattgcca
     7201 acttcaaacg tcaaatcaat gcgcttggat tttcttatga ctgggatcgt gaagtcaaca
     7261 caacagatcc aaactactac aagtggactc aatggatttt caccaagctt tacgaaaaag
     7321 gcttggccta tgaagctgaa gtgccagtaa actgggttga ggaattggga actgccattg
     7381 ccaatgaaga agtgcttcct gacggaactt ctgagcgtgg aggctatcca gttgtccgca
     7441 aaccaatgcg ccaatggatg ctcaaaatca cggcttacgc agagcgcttg ctcaatgact
     7501 tagatgaact agattggtca gagtctatca aggatatgca acgcaactgg attggtaaat
     7561 caactggtgc caatgtaact ttcaaagtaa aaggaacaga caaggaattt acagtcttca
     7621 ctactcgtcc ggacacactt ttcggtgcga ctttcactgt cttggctcct gaacatgaat
     7681 tagtagacac tatcacaagt ccagagcaag cagaagctgt agcagactat aaacaccaag
     7741 ccagccttaa gtctgacttg gctcgtacag accttgctaa agaaaaaaca ggggtttgga
     7801 ctggtgctta tgccatcaac cctgtcaatg gtaaggaaat gccaatctgg attgcggact
     7861 atgttcttgc tagttatgga acaggtgcgg ttatggctgt gcctgcccac gaccaacgtg
     7921 actgggaatt tgccaaacaa tttgaccttc caatcgtcga agtacttgaa ggtggagatg
     7981 tcaaagaagc tgcctacaca gaggatggcc tgcatgtcaa ttcagacttc ctagatggac
     8041 tcaacaaaga agacgctatt gccaagattg tggcttgctt ggaagaaaaa ggctgtggtc
     8101 aggagaaggt tacctaccgt ctccgcgact ggctctttag ccgtcaacgt tactggggtg
     8161 agccaattcc aatcattcat tgggaagatg gaacttcaac agctgttcct gaaactgaat
     8221 tgccgcttgt cttgcctgta accaaggata tccgtccttc aggtactggt gaaagtccac
     8281 tagctaactt gacagattgg cttgaagtga ctcgtgaaga tggtgtcaaa ggtcgtcgtg
     8341 aaactaacac catgccacaa tgggctggtt caagctggta ctacctccgc tatattgacc
     8401 cgcacaatac tgagaaattg gctgatgagg acctcctcaa acaatggttg ccagtagata
     8461 tctacgtggg tggtgcggaa catgctgtac ttcacttgct ttatgctcgt ttctggcata
     8521 aattcctcta tgacctcggt gttgttccga ctaaggaacc attccaaaaa ctctttaacc
     8581 aagggatgat tttgggaaca agctaccgtg accaccgtgg tgctcttgtg gcaaccgaca
     8641 aggttgaaaa acgtgatggt tccttctttc atatagaaac aggggaagag ttggagcaag
     8701 cgccagccaa gatgtctaaa tcgctcaaga acgttgttaa cccagacgat gtggtggaac
     8761 aatacggtgc cgataccctt cgtgtttatg aaatgtttat gggaccactc gatgcttcga
     8821 ttgcttggtc agaagaaggt ttggaaggaa gccgtaagtt ccttgaccga gtttaccgtt
     8881 tgattacaag taaagaaatc cttgcggaaa acaatggtgc tcttgacaag gcttacaacg
     8941 aaacagtcaa agctgttact gagcaaattg aatctctcaa attcaacaca gctattgccc
     9001 aacttatggt ctttgtcaat gctgctaaca aggaagataa gctttatgtt gactatgcca
     9061 aaggctttat tcaattgatt gcaccatttg cacctcactt ggcagaagaa ctctggcaaa
     9121 cagtcgcaga aacaggtgag tcaatctctt atgtagcttg gccaacttgg gacgaaagca
     9181 aattggttga agatgaaatt gaaattgtcg tccaaatcaa aggaaaagtt cgtgccaaac
     9241 tcatggttgc taaagatcta tcacgtgaag aattacaaga aatcgcttta gctgatgaaa
     9301 aagtcaaagc agaaattgac ggtaaggaaa tcgtgaaagt aattgcggta ccgaataaac
     9361 tcgttaatat cgtcgttaaa taacgagttt attagctcta tctgccacct tcaatagtcc
     9421 actggactat tgaagccaac taaattagtt aacattgttg tgaaataaaa agaagtaact
     9481 ctagagtatg aactttagag ttacttttag aataggtcag aatgaataga ttagtgaacg
     9541 atagcaggaa gtgtgaaatt ttattattta agatttctat tattgtagtg tcagttatag
     9601 tattagtaat gtcaatagtg ggtgcatatt attttaaaaa ttgtctttgg gacaaggaaa
     9661 gtttaaattt gacactcact ttagacactc tctttgcagt ttttattact ttctttagtt
     9721 tttcaaatga taaatcaagc aatatttttg gaatatctcc aaatgaaatt ataaggacac
     9781 agtctgaagt gtatcaattt ttatttacaa aatcttttgc aactctatta atagtgacaa
     9841 atttgttatc cattattcat tattttggag ccaaaaattt aatagtttct tttaatgaaa
     9901 cttatcctcg tattcaatcc agtgttggta tcatgtggct accactgttt ggtattctga
     9961 taatctattt tatttggctc ttaatagagg gattaaaata tatcagaaaa ataaattata
    10021 ttattcaaaa tagggaaata atctattttt attcgcaggt aaaagttgta gataaactta
    10081 ctgattctga atcgaaaaaa tacggtgaat atattgattt gtacgaatcg tgtcgtcaga
    10141 acaatttaag tgttctactt aactttcttc aaaattcgga tgataaacga ggagttattg
    10201 ctagtaactc agtgagaatt atgtttgaat ctttggataa agcagaccaa attgcggccc
    10261 tgaatatttg tagaaactat gtagcacgag aaaatgtttt aaataaagaa gatgcagaaa
    10321 aattgttaaa tgaaattgat aaaaaacttg aaattagcag ataggacaat tcaaatagag
    10381 ttgagtaaaa agtttgaaaa gtgaaacaag gagaaagcta tgccagtaaa tgaatatggt
    10441 cagatgattg gtgagtcaat ggaaggttat acacccggtg cactgccttc tattgatttc
    10501 ttagaagggc gttatgctag gatagaggct ctctcggtag aaaaacatgc ggaggatttg
    10561 ctagctgttt atggcccgga tactcctcgg gagatgtgga cctatctttt tcaggagcca
    10621 gtagcagata tgggggagct ggttagcctt ttaaatcaga tgttggctcg taaggaccgt
    10681 ttttactatg caatcataga caaggcgact ggtaaggctt tgggaacttt ttctctcatg
    10741 cgcattgacc agaataaccg agtaatagaa gtcggagcag tcactttttc tccagagcta
    10801 aggggtacac ggataggaac tgaggctcag tatctcctag ctcgctatat ttttgaggag
    10861 ctaaactatc gtcgctacga gtggaaatgc gatgccttaa atctgccatc cagacgagtt
    10921 gcggagcgtt tgggatttgt ctatgaagga accttccgcc aggcggtggt ttataagggg
    10981 cgtacgagag atacggattg gttgtctatg attgatatgg actggcctca agtcaaagat
    11041 cgtttggaaa catggctgcg tcctgaaaat tttgataaaa atggacagca gtacaagagc
    11101 ttgagagaac tttaagaggt gttgagatga ttactattaa aaagcaagaa attgtcaagc
    11161 tagaggatgt tttgcatctc tatcaggctg tcggttggac aaattatacc catcaaccag
    11221 agatgctgga gcatgcctta tcgcattcat tagtaattta tctggcactt gatggtgatg
    11281 ctgtggtggg cttgattcgt ttggttggag atggattctc atcagttttt gtacaggatt
    11341 tgattgtttt accaatctat cagcgtcaag ggattggtag tgccctaatg aaagaggcct
    11401 taaaagatta caaagatgct tatcaagtcc agctggtgac agaagagaca gaaaaaaacg
    11461 tgggatttta tcgttctatg ggctttgaaa tcttatccac ctataattgt atagggatga
    11521 cttgggcgaa tcgagaaaaa taacaaaact tgttttttct taagcaaaat ttaaggatgg
    11581 tctagtatta tataatcatt aaataaagac ctcctaactt tatttaataa agtcctaaac
    11641 ttttcttttt cataataatc tcccttaact ccacccaatc aggtggagtt ttttagctct
    11701 atttcaggct tttggggact attctaaaaa taatttttcg atatttttcg gtatttttcg
    11761 gattttggtc ggggaattgg cggggacttt tttagcgaat ataactaaga aataggtctg
    11821 tggtcgcttc agctagttca aactcaattt gattgtaagt gactgttaat tgaagaactg
    11881 gaactactgt aataatgatt ttgcttgtct agtagtggcg tattaaatga gaagtgacat
    11941 gtaagattgt ctcttcgttt acgaaatcaa aatttctatg aaattgatag aatccctaac
    12001 gttctcttaa tcttaaccgt cttgtcgtac agcggttgaa gaaaatgtaa acctttgaca
    12061 aaattcgtga actatgggat aataaaaagg aattgagtac tagttctata tcataggcta
    12121 gaaaagaccc caagctcacg accaaataag cttgaggtct tttttgacac tatttgtcct
    12181 tgtttagcca tttatcgact atacgaagaa cgacaccgac cacaattggt ccgatgatag
    12241 ttttgagtac taattccatc atgggctatc tcacctcctt tcgtaggcgg tgtagcagtg
    12301 tcgtagaata ttataccaca taagtgctaa acttaggagt cacccaatca ggtggctttt
    12361 ttgtttgtgg cttggttttt tgatataata gagccatgag tagaatttta gataatgaga
    12421 taatggggga tgaggagtta gtagaacgca cgctccgtcc tcagtattta cgtgaatata
    12481 tcggacagga taaggtcaag gaccagctac aaatctttat tgaagctgcc aaaatgcggg
    12541 atgaagcgtt ggatcatgtg ctcttatttg ggcctccagg tctcgggaaa acgaccatgg
    12601 cctttgttat tgccaacgaa ctgggagtca atcttaagca gacgtcgggt ccagtcattg
    12661 aaaaagccgg agatctggta gctattttga atgagttaga gcctggggat gtacttttta
    12721 ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt gctttatagt gctatggagg
    12781 acttctacat cgatattatg attggggctg gtgagggtag tcgtagtgtt catttggagt
    12841 taccaccttt taccttgatt ggtgcgacga ctcgggctgg tatgctctcc aatccgctac
    12901 gggcacgttt tgggattaca ggccatatgg agtattatgc ccatgctgac ttgacagaaa
    12961 ttgtcgagcg gacggcagat atttttgaga tggaaatcac tcatgaggca gcatctgagt
    13021 tggccctacg tagtcgtggg acccctcgta ttgccaatcg tctcctcaag cgcgtgcgcg
    13081 attttgccca gataatgggg aatggggtaa ttgatgatat tattaccgat aaggctttga
    13141 ctatgctgga tgttgaccat gaaggtttgg actatgtgga tcaaaaaatc cttcgtacca
    13201 tgattgagat gtacagtgga ggacctgttg gtctaggaac tctttctgtg aatatcgccg
    13261 aagagcgtga gacagttgaa gacatgtatg agccttactt gattcaaaaa ggttttatca
    13321 tgcggacacg gtctggacgg gtggcgactg ctaaggcata tgagcactta ggttatgaat
    13381 acagtgaaaa ataagcaaga aatcttagag gcttttagag aaaatccaga tatgatggcc
    13441 attctgacga tcatccgaga ccttggtctg aaagactcgt ggttggcagc aggttctgtc
    13501 agaaatttca tttggaatct tttgtcagac aaatcccctt ttgatcatga aacagatata
    13561 gatgtgattt tctttgatcc agatttttct tatgaggaaa ccttattact gaagaaaaag
    13621 ctgagagagg attttcctca gtaccagtgg gaattgaaaa atcaggtcta tatgcatcag
    13681 cacagtcctc acactgcttc ctataccagt tctcgtgatg ctatgagtaa gtatccagaa
    13741 cggtgtacgg cagttggact gcgcttgaat gaagaatcag attttgaact ctatgtacct
    13801 tatggtttgg aggatatttt gaattttcaa gttcgtccaa ctcctcattt cttagaaaat
    13861 gaagaccgaa tggaactcta tcaaacacgt ttatccaaga aaaattggca ggagaaatgg
    13921 aaaaatttga tttttaaaaa tacttaagga aactttaagc tagggagtgt acactaagtt
    13981 cataagttaa gaagacctta acttaaactc ctaaaacttt ttcataataa tctccctata
    14041 aaaataaagt cgcccaatca ggcggcttat ttttttgaaa aatgggcttg gtgcctgaga
    14101 ataaatagct tagtgataga agaaaatggg gaaatatggt ataatgaaac gatagatttt
    14161 tgaataggaa taagatcatg tttggatttt ttaagaaaga taaggctgtg gaagtagagg
    14221 ttccgacaca ggttcctgct catatcggca tcatcatgga tggcaatggc cgttgggcta
    14281 aaaaacgtat gcaaccgcga gtttttggac ataaggcggg catggaagca ttgcaaaccg
    14341 tgaccaaggc agccaacaaa ctgggcgtca aggttattac ggtctatgct ttttctacgg
    14401 aaaactggac ccgtccagat caggaagtca agtttatcat gaacttgcca gtagagtttt
    14461 atgataatta tgtcccggaa ctacatgcga ataatgttaa gattcaaatg attggggaga
    14521 cagaccgcct gcctaagcaa acctttgaag ctttaaccaa ggctgaggaa ttgactaaga
    14581 acaacacagg attgattctt aattttgctc ttaactatgg tggacgtgct gagattacac
    14641 aggcgcttaa gttgatttcc caggatgttt tagatgccaa aatcaatcca ggtgacatca
    14701 cagaggaatt gattggtaac tatctcttta cccagcattt gcctaaggac ttacgagacc
    14761 cagacttgat tatccgtact agtggagaat tgcgtttgag caattttctt ccatggcagg
    14821 gagcctatag tgagctttat tttacggaca ccttatggcc tgattttgac gaagcggcct
    14881 tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg atttggagga gtttaggagg
    14941 aaatatgacc caggatttac agaaaagaac cttgtttgca gggattgccc tggctatttt
    15001 cctaccaatt ttaatgattg ggggcctctt gcttcagata gcaatcggaa tcgtagccat
    15061 gctagccatg catgaacttt tgaagatgag aggtctagcg accatgacga tggagggcct
    15121 cttgaccctc tttgcaacct ttgcattgac cattcccttg gagaattacc tgactttttt
    15181 gccagttgat gggaatgtgg ttgcctatag tgttttgatt tcaatcatgt taggaacgac
    15241 cgtttttagc aagtcttata cgattgagga tgcggttttc cctcttgcta tgagcttcta
    15301 cgtgggcttt gggtttaatg ctttactaga tgctcgtgtt gcaggtttgg acaaggctct
    15361 cttagccttg tgtatcgtct gggcgacaga cagtggtgcc tatcttgttg ggatgaacta
    15421 tgggaaacga aagttagcac caagggtatc gcctaataaa acccttgagg gtgccttggg
    15481 tggtatttta ggagcaattt tagtaaccat tatctttatg atagttgaca gtacagttgc
    15541 tcttccatat ggaatttaca agatgtcagt ctttgctatt ttctttagca ttgctggaca
    15601 atttggtgat ttactagaaa gttcgatcaa acgtcatttt ggtgttaagg attctgggaa
    15661 atttatccct ggacatggtg gtgttttgga tcgtttcgat agtatgttgc ttgtatttcc
    15721 aatcatgcac ttatttggac tcttttaatc aaaagacgga ggaaacgcta tgctcggaat
    15781 tttaaccttt attctggttt ttgggattat tgtagtggtg cacgagttcg ggcacttcta
    15841 ctttgccaag aaatcaggga ttttagtacg tgaatttgcc atcggtatgg gacctaaaat
    15901 ctttgctcac attggcaagg atggaacggc ctataccatt cgaatcttgc ctctgggtgg
    15961 ctatgtccgc atggccggtt ggggtg
//
LOCUS       DAVLZS010000042        15677 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLZS010000042 DAVLZS010000000
VERSION     DAVLZS010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15677
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.042"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            118..1602
                     /locus_tag="VYO88_001535"
     CDS             118..1602
                     /locus_tag="VYO88_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1719613.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            complement(1653..2381)
                     /gene="yaaA"
                     /locus_tag="VYO88_001536"
     CDS             complement(1653..2381)
                     /gene="yaaA"
                     /locus_tag="VYO88_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1719614.1"
                     /translation="MKILIPTAKEMNTDLPSIEATPLKPESQAVLDALALYSASQLES
                     FYKVSAEKATEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(2460..2624)
                     /locus_tag="VYO88_001537"
     CDS             complement(2460..2624)
                     /locus_tag="VYO88_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV1719615.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LVAVWLGWPK"
     gene            complement(2691..4286)
                     /locus_tag="VYO88_001538"
     CDS             complement(2691..4286)
                     /locus_tag="VYO88_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719616.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            complement(4298..4708)
                     /locus_tag="VYO88_001539"
     CDS             complement(4298..4708)
                     /locus_tag="VYO88_001539"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1719617.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(4824..5615)
                     /gene="yghU"
                     /locus_tag="VYO88_001540"
     CDS             complement(4824..5615)
                     /gene="yghU"
                     /locus_tag="VYO88_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV1719618.1"
                     /translation="MSAYQLPTVWQDEASDQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(5628..8324)
                     /locus_tag="VYO88_001541"
     CDS             complement(5628..8324)
                     /locus_tag="VYO88_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1719619.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKITNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            8628..9812
                     /gene="mntE"
                     /locus_tag="VYO88_001542"
     CDS             8628..9812
                     /gene="mntE"
                     /locus_tag="VYO88_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV1719620.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(9955..11826)
                     /locus_tag="VYO88_001543"
     CDS             complement(9955..11826)
                     /locus_tag="VYO88_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1719621.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(11823..13007)
                     /locus_tag="VYO88_001544"
     CDS             complement(11823..13007)
                     /locus_tag="VYO88_001544"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1719622.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQNKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQARGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(13019..13786)
                     /locus_tag="VYO88_001545"
     CDS             complement(13019..13786)
                     /locus_tag="VYO88_001545"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1719623.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLERLL"
     gene            complement(14052..14900)
                     /locus_tag="VYO88_001546"
     CDS             complement(14052..14900)
                     /locus_tag="VYO88_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1719624.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(14902..15276)
                     /locus_tag="VYO88_001547"
     CDS             complement(14902..15276)
                     /locus_tag="VYO88_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1719625.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(15350..>15677)
                     /gene="glmM"
                     /locus_tag="VYO88_001548"
     CDS             complement(15350..>15677)
                     /gene="glmM"
                     /locus_tag="VYO88_001548"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="catalyzes the conversion of glucosamine-6-phosphate
                     to glucosamine-1-phosphate; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1719626.1"
                     /translation="LSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKA
                     MEVPAIKAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVR
                     AEIGID"
BASE COUNT         4560 a         3562 c         2958 g         4597 t
ORIGIN      
        1 taaaagccac ttatattatt ctaatttttc cgattactaa cgacaatttt cttgctctaa
       61 tttttttata ctacttagac aaaaaaagat ataatgaatt atggaggaaa tacccgtatg
      121 agaaaccttt tatccacaaa agttcaaaga caattacgct taatggaaac cctaattcag
      181 aatcgtaatt ggatgaaatt acatgaacta gccgaaaaat taggatgtac agaacgaatc
      241 ttaaaaagtg atttaaatga attacgtatt gcctttccat ctattaacat ccaatcttct
      301 gttaacggaa tcatgataga tttagaagtt aacactagtg tagaagatat ttatcaatat
      361 tttcttgcta attctcaatc ttttcaatta ctagagtata tgttcttcaa tgaggggcta
      421 cctatttatc gaacaataga aaatctttac tttagtagtg ccaacctcta tcgactgggc
      481 agaaatatta caaaggttct ttcatctcag tttcaaattg aattatcttt tactccatcc
      541 gagatacgtg gaaatgagat cgatattcgt tacttttttg cccaatactt ttctgagcgc
      601 tattatttcc tagattggcc ttttcctgac cttcctgagg aagatttaac agagtttgct
      661 gacttcttct ataaaatcac gaattatcca atgcgatttt caatttatag aatgtacaaa
      721 ctgatgatag ctatcagtat ccacagggtt aaaaatggtc acttcattga cctccccaac
      781 cacttttaca aagaatatta tcctctttta aagagcattc caaatttcca ggagacactt
      841 gcttatttct ctaaacattt tgggcttgaa atgactccag atacaatcgc tcaaattttt
      901 atttcttttc ttcagaatga tattttccta gatcctcaag aattcttcaa ctctttagaa
      961 gataacagtc aagcaagata ctcttaccaa ttacttagtc aaatattaga acgcctatca
     1021 aaacaatata agattacttt tactaaccac gatgagctga tttggcattt acacaacact
     1081 gctttctttg aaagacagga aatcttttct accccaatct tatttgaaca aaaagcattg
     1141 acgattaaaa aatttgaagt ttacttccca gactttatgg gaagtgcgcg tcaagaactg
     1201 gctcaatacc gtcaggcaat tggacagcat gaccatcctg aacagttgga acacttgatg
     1261 tacaccatct taacccatgc tgaaaacctc tctactcagt tgttagaaaa tcgaccacct
     1321 atcaaggttt tgattatcag taactttgac catgctatat cccttacctt tgttgatatg
     1381 ctttcctatt actgtaataa ccgctttacc ttcgatattt gggatgaatt aaaaacaagt
     1441 cctgagattt taaatcagac agattacgat atcatcgtgt ctaatttcta tatttcaggg
     1501 attaccaaga agtttatttg ccgaaatcat ctgtcaatca tgaatttggt taatcatctt
     1561 aacaccttat caaatgagat tcatttgtcc aatactttat aagttatcaa aaaagtcagc
     1621 ataatcgtgc tgacttttct cttatctgat ttctatactt cctttacaaa aaccaatccc
     1681 tgtggttgtg acaaatcttc tcggtaaaca aatccagcaa agttcaagcg acgtgcttcc
     1741 cccacagttt gtacttgatt ttctattaaa gctgttagaa aggccccgcg cgctttcttg
     1801 gagatagttg agtgaatctt cagttgaccg cctctatcct ccatgaattt gaaggtcacc
     1861 atctttgctc tgatttcctt agaaaataca gtctcaaact ctgatgacaa gagagagaaa
     1921 atcacttctt ccttcttcag agcttcatca tagactgcct tccaatggct cttcaaagtc
     1981 ttaccagcga cttttaattt catcaaaaaa tccaaacggt gaggagccat gggtgacaag
     2041 gctggaacaa caccgtacaa agccgaggta atgaagacat gattttcaag ataatcttgt
     2101 tccgcctcgg tcagcttatc tctcttaatg ttgcggtaca taagcccatc aaaaagtttc
     2161 aaggctggat agtgttgagc agtttgcctt ttcaaagctt ggatattttg aaattcttcc
     2221 gtcgctttct cagctgatac cttgtagaaa ctctccaatt gactggcaga atagagagcc
     2281 aaggcatcaa gcacggcctg actttctggt tttaaaggag ttgcctcgat acttggcaag
     2341 tctgtgttca tttcttttgc tgttgggatt aaaattttca tattgatagt gtagcatatt
     2401 ttttagccac aaccaagaaa ttcatttgaa aaacctcggt ttgaccgagg tttttctatt
     2461 tatttgggcc atcctaacca gacagccacg agaacaaggg ctatgccagc taaacttgtt
     2521 aagatagata agaatttatc ttttttctcc ttgaactgag aaaaacctat cttcaaagcg
     2581 agcagtccga gtagcattga agcaaccatc aaataaaaac ccatttcttt gtcctccatt
     2641 aggcttaatt taccttatta taacatatac tttctgaaaa aaacctattt ttaccgtagc
     2701 ttaaaggtct tgagataatt gtcttttcct acttgacctt cgaaggtttt accattttca
     2761 aggtaaggaa ggtcatcgga tactgaagcc ttgaccttgt atatcttgcc atcaacttta
     2821 aagaagtaga cagtgtctcc cttgataaca gctgatttga ggtctgctac tactccattg
     2881 atgctttctg tcgttgcatt gtcaatttca aggtcgtttt tattggcata cttgctgagc
     2941 atctcttcca ctgtagtagc aacgataaca ttttggtact cgactgcgtc taccagggcg
     3001 tactctttga ccaagccagc attgtccttc aagcccatga tgtagagagg cttgtcattg
     3061 aggttgatga ggattgggaa ggttgctttg taggatttct cctgaacagc accttctgct
     3121 gattcacggg ctgattcttc tgtcgcagaa gccaagctat acttagtgat ttctcctgtt
     3181 cgcatatttt caaggatgaa accaagatta ctctcatccg cattagccga cgtcacacct
     3241 gtgtagagat agatgtcatt accgatagac aagtaattat agccattggt agtctgggtc
     3301 acgtttttct tggaaatcat ggcattcaag aaaccgtcct tgtacttgcc gttgtagttg
     3361 atttgctcaa tggtttcctc tgctggatag atcctgtcca cccattctgg aacatctgat
     3421 aagctgtatt ccttggtttc tccatttgta gcatccaaga taatgactga agcaggacga
     3481 ggaacagcaa gtccaaattg cttttggtaa accgttgcta catagaaagg attgccctca
     3541 tcgtccacct caaaagatgg agttttaaag attttggtcg ggtacttcaa gcgcaggtga
     3601 cgtttgacat cacggttaaa atactccgag tctgaatact tgattggtgt cttcaagtcc
     3661 accaaatccg catttccagt taccatgtcc accttaatat actcaccgat tcccttggct
     3721 tgattgttaa accatttgat agggtctgca tattctagtg gtgtgacccg ataaggtttc
     3781 ccatcaattg tcaattgggt ataggtatct gccgctacgt attgcgacac cttatcggtt
     3841 agggaaccca agtagcggtc tccaattttt tcagcagtac ttctatctag gataggaacc
     3901 ttactggtgt cactcttagg aaattcagta aagtcttttt ccgtaaccgt gactacattg
     3961 gcataatttt tagcctgaaa catgctggaa gttaccaagg aaaccaaagc tgccaagaga
     4021 agaattcctc caatcgaagc taacagaatt ttccctaacc gattgatttt gaaaccctca
     4081 agatttaagg cagcttccgc cttaccgtgg cgcacatgaa ccgttttgac aaggtttatc
     4141 cccttgccaa agccaaataa gattgccaca actaacaaat gcccacagag gaagaagaga
     4201 aattcccagc tggtcaggtt aaggggcggt aaaaagatat accaggtcgt tgcgataaaa
     4261 ataagttcaa agactattcg tttcatttgc tttcctccta aatgattcgt ccttccaagt
     4321 gatccagctc atgctggcaa atctgagctg ggaagcctgt caaggtaatg gtctgttcct
     4381 gccacttgct gtcacgatag gcaagcctta tggtttcata acgcttagtt gatctcacac
     4441 ctaccaagga caaacagcct tcttctgcct cataggatcc ttcaaaggac agaagcactg
     4501 ggttaaacat gaccacagga accaagccaa gattaaagat aatcacgcgc ttctgcaccc
     4561 caatcatatt ggcagctaga ccaacacagg tatcacgatt tgctaagagt gtatcctgca
     4621 aatctctggc aagataaagg tcctcctgac ttgccggctg agacacttga gataaaaata
     4681 agatatcctt cacaattttc ttttccactt cctcacactc ctcttgcttt ttactatatt
     4741 atagcaatta tagcacaaaa gccgataact gcaaaccctt tccctcaact gtagcaaaaa
     4801 gccatccgaa gatgactttt ttgctattta atttctgtat aagttacttc caatccacgc
     4861 ttaacagctg gacgattggc aattttttct gcccatttta ctagattttg ataacttgag
     4921 gcatccaaga attttgcaga accttggtaa agatttcctt gaactaactg tccataccaa
     4981 gaccagatag caatatctgc aatcgtatag tcattgcctg caatataagg tttctgagcc
     5041 aattccttat ccaataaatc caactggcgt ttcacttcca tcgtaaaacg gttaatagga
     5101 tattccaatt tttcaggagc ataattgaag aaatgtccaa atcccccacc tagaaaaggt
     5161 gctgcacctg cttgccagaa tagccaattc aaaacttcta ccttttccac aggattactt
     5221 ggtaaaaagg ctccaaattt ctcagcaagg taaagaagaa tatgagcaga ctcaaagact
     5281 cttacgtttt cagtacctga ctggtccaat aaggctggaa tcttggaatt tggattgagc
     5341 ttcacaaagt ctgagccgaa ttgatcccca tccatgatag caatcttata caagtcgtaa
     5401 gccgcttcct taaaaccagc ttctagtaat tcttccaata agatagtaac cttcacacca
     5461 tttggtgttc ccagtgaata aagctgaaaa gcttgttctc cttttggcaa gttttgttcg
     5521 aaacgggcac ctgctgttgg tctgtttagc cccgtaaaag ctccttgatc actagcttca
     5581 tcctgccata cggtcggtaa ttgatatgct gacatccgaa acctctctta aatcgcattc
     5641 ttgtcaaaac cgagtttgcg ttgaataaac ttaacgattt cgacgatgat aatcattgag
     5701 aagcttccag ccataacaat tccccattgt gacaagtcta gtttggttac gtggaagatt
     5761 ccttcaagcg gttctacaac gattgttgcc atgagaagga taaaggatac caagatggac
     5821 cagttaaagg tcttagactt gaatgggcca actgtcaaga tggattggta gacagacttg
     5881 acattgtagg catggaagag ctgaatcaaa ccaagggttg caaaggccat cgttagggca
     5941 tctgcatgaa tagcatgatt gtcacccaca tgaactgggt aagcaatcgc aaggccataa
     6001 acactcataa caagagctgc ttggagtaca ccttgataaa tgatagaact caaaacacca
     6061 cctgagaaga agcttgcctt gcgtccacgt ggtttatgat tcatgacacc aggctccgca
     6121 ggttcaacac caagagcgat agctgggaag gtatccgtta ccaagttgat ccacaaaaga
     6181 tgaaccggct gcaagacatc ccaaccaaac aaggttgata ggaagatggt taatacttca
     6241 gcagtattag cagaaagtag gtactgaata gtcttttgaa tgtttgagaa gaccttacgt
     6301 ccttcttcca ctgcgacgat aatagtcgca aagttatcat ctgcaagaat catatcagaa
     6361 gcccccttag aaacctctgt accagtgatt cccataccga taccaatatc ggctgttttc
     6421 agagctggcg cgtcattgac accgtcacct gtcatggcaa cgactttacc ttgtttttgc
     6481 caagccttga cgatacgaac cttgtgttct ggagacacac gggcataaac agagtattga
     6541 ccaacaactt tttcaaattc ttcatctgac agttcattga gttcagcacc agttaaaacg
     6601 tgaccttctg tatcgtttgc gtcaatgatt cccaaacgtt tggcaatggc ttccgctgtg
     6661 tcttggtggt cacctgtaat cataattgga cggattcccg cttccttagc cacacgaaca
     6721 gcctcagcgg cttcaggacg ttcagggtca atcatcccaa tcaaaccagt aaaaattaaa
     6781 tcattttcaa gctcttcaga agtgagattt tctggaatgc tgtcaataat cttataagca
     6841 cctgcaagga cacgcaaggc ttgatgagcc atttcagagt tgtttgtatg aatgagattt
     6901 gtaatcttct catcaatcgg agcaatatcc ccagccttat cacgaagaag acaacgtttt
     6961 aagagttggt ctggcgcacc cttgactgct acaaggaaac gaccatctgg caatgggtga
     7021 actgttgaca tgagcttacg gtcagagtca aatggcaatt cagctacacg aggatatttc
     7081 tctaagaaac ctttgacatc atagcccttg tccaaggcat attggataaa ggctgtttcg
     7141 gttgggtcac caatcaagtt accttccaca tcgattttcg tatcattggc caagacaact
     7201 gaacgaagta gtggcatttc aagacctagt tcaatatcat cagctgagtc atgtagaacc
     7261 gcatcgtaga agactttttc gactgtcatc ttgttcatag tcagcgtacc agtcttatca
     7321 gaagcgatga tttcagttga accaagtgtt tcaactgctg gcaacttacg aacgatggaa
     7381 tgtcgtttgg ccaaaacttg agtaccaaga gaaagaacga tggtaacgat agcaggaagt
     7441 ccttctggaa tggctgcaac ggcaagggca acagaagtca acaactcacc aagtggattt
     7501 ttcccttgaa tgaagacacc cactacaaaa gtaacaaggg caatgaccaa gatagcatag
     7561 gtcaagacct tagaaaggtt gttcaaattt tgtttgagtg gtgtatcagt ctcatccgca
     7621 tcttgaagca taccagcaat atgaccaact tcagtgtaca tacctgtatt gacaacaaca
     7681 cccatcccac gaccataggt tacgtttgag ttttggaagg ccatgttgac acggtcacca
     7741 ataccagcat ctgtcgcaag ctcgactgac aagtcttttt cgactggtac agattcacct
     7801 gtcaaggctg cttcttcaat tttaagagag ttggcttcta tcaaacgtag gtccgctggt
     7861 accacgtcac ctgcttcaag ggcaacgata tcgcctggta ccaattcttt agagtcaatc
     7921 tctgccatgt gtccatcacg aagaacgcgg gcaactggac tagacatgga tttgagggct
     7981 tcaatagctt cttcagcttt tccttcttgg taaacaccaa aggcagcgtt gatgataacc
     8041 acagctagga tgataatggc atctgcgata tcttccccac cagaagtcac gactgacaag
     8101 attgctgccg caactaggat gataatcatc aaatccttaa attgctcgat gaatttgacc
     8161 aagattgatc gtttctcgcc ttcttcgagt tcattgtgcc caaattcggc aaggcgcttt
     8221 tccgcctcac ttgatgacaa accttgctcg gtcgcatcca cagcctgcaa gacctcttca
     8281 gggctctgag tataaaacgc ttggcgtttt tgttcttttg acatgtgtct cctccttgac
     8341 attgtgtgca aaacagactc tctttctgtc atatcttttc acgacaaaca aaaagagacc
     8401 tgttaatcat aacaagtctc gctgtttaag atagggccgg aaagcatact tttcagcata
     8461 aaattcggaa tgacgacact atcacaggtt tctgccagct actcccttga gtagtaccat
     8521 tataccaaat tttggggagt tttcaaagag taaaaactgc cttatttgaa tttttccttg
     8581 aaaaccagta taatggtaga atgctatgtg actagaaagg aagttgaatg aagcaatcta
     8641 tctcaaatct caagttagct gagcgtggag ccattatcag tatttcgacc tatttgatct
     8701 tgtctgcagc caaattagca gctggtcatc tccttcattc atccagtttg gtggccgatg
     8761 gttttaataa cgtatcggac atcattggaa atgtggccct cttaatcggg attcggatgg
     8821 cgcgccagcc tgcagaccgt gaccaccgtt ttggtcattg gaagattgaa gatttggcaa
     8881 gcttgatcac ttctatcatc atgttctatg tcggtttcga tgttctaaga gataccattc
     8941 aaaagattct cagtcgggaa gaaacggtca ttgatcctct tggtgcaact ctaggaatca
     9001 tttctgcagc gattatgttt gtggtctatc tctacaatac tcgcctcagt aagaaatcca
     9061 actccaaggc gctgaaggca gctgctaagg acaatctttc tgacgctgtt acctcacttg
     9121 gaaccgccat tgccatccta gctagtagtt ttaattatcc gattgtggat aaactggttg
     9181 ctatcatcat cactttcttt atcttgaaga ctgcctatga tatcttcatc gagtcttcct
     9241 ttagtctttc agatggcttt gacgaccgcc tgctcgagga ctaccaaaag gctatcatgg
     9301 aaattcccaa aatcagcaag gtcaaatcgc aaagaggtcg cacctacggt agcaacatct
     9361 acctggatat tacactagag atgaatcctg acttgtctgt ttttgaaagc catgaaatcg
     9421 cggatcaggt cgagtctatg ctggaggagc gttttggcgt ctttgatacc gatgtccata
     9481 tcgaaccagc acctatccct gaggatgaaa ttttagacaa tgtctataaa aaattgctta
     9541 tgcgtgaaca attgattgac caaggaaacc aactagaaga actcttgact gatgattttg
     9601 tctatattcg ccaagatgga gagcagatgg ataaagaggc ttataagacc aaaaaagagt
     9661 taaattctgc tatcaaggac attcaaatta cttccatcag tcaaaaaacc aaactcatct
     9721 gctatgagtt agatggtatc atccatacca gtatctggcg tcgccacgaa acctggcaaa
     9781 atatctttca tcaagaaacc aaaaaagaat agagaaatcc tttcatgaga cgggattttt
     9841 ctattctttt atactcaata aaaatcaaag tgcaaattag gaagccggtc acaggctgta
     9901 cttgagtcgg caatgtgaag ccgacatagt ttgcactttg attttcgaat agtcttaact
     9961 atcaaattca ctgagatact catagcgttc gtatttttca aggagtgctt catttttctc
    10021 atccaattct ttttggagag tagccagctt accaaagtca gagccgttag cctgcatttc
    10081 ctcttcaata gcagcgatac gtttttccaa ggtttcaata tcaccttcaa tacttgccca
    10141 ctcctgcttt tcttggtagg tcatgcgttt cttgtcttct cgaaccttga ccactttttc
    10201 cttttcggcc ttttgcactt gattggccat atctgtttca aaagcttttt catcaagata
    10261 gtcggtgtaa tgaccaaaga aaggacgaat cttgccatcc tcaaaagcga gaatcttggt
    10321 cgctacctta tccaagaaat agcggtcgtg actgactgtt aaaacgggac ctgcaaaacc
    10381 ttgcaagaaa ttctctaaga ctgtcaaagt tgcaatatct aggtcattgg ttggctcgtc
    10441 taaaagaaga acatttggtt tttccaaaag cagtttgagg agataaagac gttttttctc
    10501 accccctgac aatttctcaa tcaaggtccc atgcgtcgaa cgtgggaaga ggaattgctc
    10561 cagcaactca gcgatggaag tcgtagaacc accactggtc ttgacctcct ctgccacttc
    10621 ctgcaggtaa ttgatcacac gcttgctttc atccaaaccc tcaatttgtt gagagaaata
    10681 ggcgatgcga acagtttccc caatcacaac ttgtcctgct gtcggctcaa gacttcctgc
    10741 aatcaggtta agtagggttg attttccaac accattgtcc ccaacaattc caatacggtc
    10801 tttagcctga actaagagat taaaattttg caaaatgggc ttattttcat aggcaaagga
    10861 aacatcctga aactcgatga ctttcttccc aatccgactg gtttcaaagt tcatagtcaa
    10921 gtctgtctca gcactactgc ctgaaacttc ctttttcaga tcatggaaac gattgatacg
    10981 agcttgttgc ttggtcgcac gtgcctgcgg ttgtctgcgc atccaggcca gttcttgttt
    11041 gtagagttgt tcttttttat gaagtagagc tgcatcgcgc tcgtcctgtt ctgccttaag
    11101 gcgaacatag tcctggtaat tgccctgata ttctgtcaag cctgctcgct ccaactcgaa
    11161 aatccgtgtt gacaaagcgt ctaagaaata acgatcgtga gtgataaaaa ggacggtctt
    11221 cttagaattt ttcaaaaaga gggtcagcca ctcaataatc gcaatatcca gatggttggt
    11281 cggctcatcc aaaagcaaga ggtcgtggtt gccaagtaag acttgtgcca actgtacccg
    11341 tcttctcaga ccacctgaca attccccaac aggagtagat aagtcttgaa tgcccaattt
    11401 gctaagaacg gtcttgacct gactctcgat ttcccaagct tggagagagt ccatctctgc
    11461 catgacacgt tccaaacgcg cctgcttgtc ctcactatag tcgagcataa tcaattcata
    11521 ctcacgaatg agctggattt ccttgagttc actagataga accgtatcca aaactgtctt
    11581 tctatcatca aaatcaggat cctgagtcaa gtaaccaatc tggtaatcat ttttagctga
    11641 aaaaggactg acatccccat caaatccaga aacaccagaa aggacgtcca aaagggtggt
    11701 cttgccagtt ccattgacac cgattaaacc aattctgtct aagtcatgga taataaagga
    11761 aatatcccta aaaacggtct tgtcaccaac ggatttactt agtttttcaa cgataaaatc
    11821 actcattttt tctccctcag gtaagcatgg atggcttcac gattattctc caattctcca
    11881 tcgacaatgg caaactcaat ctctgttaaa atctctccca agtctgggcc tggctgatag
    11941 ccatattcct tgatcaaaat atcgccatta atctgaatct ctttcttgtc atggatagtc
    12001 aagctttggt atttttctgt gatggcttgt gggttgactt cttttcctcg agcttgacga
    12061 agattttcag cctgtaaaag caaatctatg tcaaagcgat aacaatctcg cttgctcaat
    12121 tctccatttt cacgcagagc caaaataatc agcaaatcct gaacttgctt ggcaaactgg
    12181 cgtgaggtct tccaagattt caaaaatgac tgcgcatttt caatctccaa agcccatagt
    12241 aaagccgccc aggcttgttc agaggattca aaagtaaaat cagtctccaa atcaaacagt
    12301 ctgttgagct tgttctggct agatgccata tcagggagat agtcataagc ttgactctca
    12361 atcatggaag ccaagcccct tctccaaaat ggagccagca agagtttatc aaactcgacg
    12421 aaggtacgct ctacagaaat tttctccaaa agcggcgtca aggtcttcat agctttaaat
    12481 gtttctggct caagtgcaaa accaagacta gcctgaaaac ggaaaccacg cataatccgt
    12541 aaagcatctt cgttgaaacg ctcactagcc actccaactg ctcgcaagac ttgcttttcc
    12601 aaatcttcta aaccatggaa caagtcaacg atttctcctg tctcatccaa ggcaaaggcg
    12661 ttgactgtga aatcacggcg tttgaggtct tcttctagcg agcgcacaaa ggaaaccgca
    12721 ctgggtctgc gatagtccac atagacatcc tctgtccgaa aggttgttac ctcatactcc
    12781 tcatccccat ctaagaccaa gacggttcca tgctcgattc cgatatcggc tgttcgcgga
    12841 aaaatctgct tggtctcttc tggataagaa gacgtcgcaa tatccacatc gtggataggg
    12901 ctatggagaa gggcatctcg aacagagccc ccaacaaaat aagcctcaaa gcctgcttct
    12961 ttaatttttt ctaatactgg taaagccttc tgaaattcag aaggcatttg cgttaatctc
    13021 ataataagcg ttctaatcca tagacaagct catgacgctt gacaacttct ttaattccca
    13081 aattgactcc tgtcatgaag gagatgcgat cataggagtc atgacggagg gtcaaccctt
    13141 ctccctgatt gccaaagatg acttcctgat gagctaccaa gcctggcaaa cgaactgagt
    13201 ggatgcgcat accatcaaag tcagcaccac gagcaccagc aatcagctct tcctcatctg
    13261 ctgcaccttg ctgaattgac tctcgaacct ctgccatcaa ctcagctgtt ttaatggctg
    13321 ttccactcgg agcatccttt ttcttgtcat gatggagctc aataatctcc acatttggga
    13381 aatatttggc agcctgcgtc gcaaattgca tgagtaagac agcacccaag gcaaagttag
    13441 gggcaatcag gccacccaag tcttgggcac gagaaaattc ttttagctct gcaatttctt
    13501 cactcgtgaa accagtcgtt ccaactactg gagcaaagcc attttcaaga gcaaaacgtg
    13561 tattttcgta ggcaacagct ggagtagtaa agtctaccca gacatccgct tcaaaaccag
    13621 ctaaatcagc cttatccttg aaaacaggaa taccctgcca ttctgactca gactcaaaag
    13681 gatccaaaac tgctaccaag tccaaatctg aatcagtcaa gaccatctgg caagcagctt
    13741 gacccatctt tcccttaaaa ccggcaataa ttactcgaat actcatctct actcctgtct
    13801 aagatacaaa gcctgtaaga acacaaagtg aaaataggaa ttctgatcaa gaagtgtcta
    13861 ctccttggaa gaactatctt tttcacacag ggttccaggc gtgttcaatt atcaagatac
    13921 aaaggatctt agccacccat gaaaaatagg gaatggcact gactttccac gaaaggcaag
    13981 acagacatct tttttcaaga ggcaggtagt ccgtgttcaa ttgctaagat taactagcct
    14041 agaagtgcct actaaatcac tggaatataa cccagagcaa tacttcctgc tcctagatgc
    14101 gttccaatga cactaccaaa tgtagcaagt gaaacatccg aacccaagcc aaaatcaagc
    14161 aaatgctgac gcaattcttc agccttttca ggagcattcc catgaatgac aatgacccgg
    14221 tattgacctg aagccgttgt ttccttgata atttcaatta agcgtttggt ggccttcttt
    14281 tcagtacgaa ctttttcgta aacttcaatc acaccttgat cgttaaaata aaggattggc
    14341 ttaatgctaa gcaaattgcc caaaatggca gccccatttg aaaggcgtcc accttttacc
    14401 aaatgatcca agtcatctac catgataaag gctgacgtac ggctgatttg aatggctagc
    14461 ttatcctgaa tgctggcaaa atcatcgccc tgatcacgcc aattaaagac gctttcaacc
    14521 atgatgccta ggggagcact tgtaatcaaa gtgtctggga aagcaatggt taagccctca
    14581 tagtcatcga ccatatactg gatattttgg taaaaacctg aaattccaga agataggaaa
    14641 agccccaagg catgtgtata gccttgttct ttgagcgaag ttaagatttc atctaacttg
    14701 gcaatacttg gttgactggt cttaggcaat tcagaagcct gagccatttt ttggtaaaat
    14761 tcctcagcag acagattgat gccttcgaca tattcctcac catcaatatt gacaggaata
    14821 tccaagacaa acaagtcttc tctttgcaag atctctgcac tgagataagc agaggaatct
    14881 gtgaaaacag ctaatttcat attagaactc caaattaatt cctggtaagt ctaatgcaat
    14941 ttcagtcact tcgtaagtca aacgattgag catgttcaaa catgggcgag ccaaggtttc
    15001 cacctcttct tggttcaatt cacttggttc attgacaata cggccatcga tatggtttac
    15061 ttgtgagatt gttccactaa tgacaaactt atcaaataca atcataaagc tcaagatgac
    15121 aatcaaggaa gtcacttgat tttcttggtc atgttggagc aattggaaat tcacatccac
    15181 cttggtttca ggagctccat tttcattttc ccattcaaaa ttacgcgcat caaaatgata
    15241 ctgactaaca aattcttgtt cacgtttaag attcatgtct ttctccatcg gctacaatat
    15301 tataagctat tgtaccataa ttttttattt tcatctagtt ttctaggatt tagtcaatcc
    15361 caatttcagc acgaactaca tctgtgatgg tatcaacata gtagtccact tcttctgttg
    15421 taggcgcttc tgccataaca cgcaagaggg gctctgttcc acttggacga acaaggatac
    15481 ggccgttccc cgccatttct tcttccatct tctcgatgat ggccttgata gctggcactt
    15541 ccatggcctt ttccttcatg acgttttcca ctcggatatt aactaatttt tgtggataaa
    15601 tcgttacttc tgccgccaac tctgataagc tcttaccagt ttccttcatg attttagtca
    15661 attgaactgc tgataat
//
LOCUS       DAVLZS010000043        15186 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLZS010000043 DAVLZS010000000
VERSION     DAVLZS010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15186
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.043"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..732
                     /locus_tag="VYO88_001549"
     CDS             <1..732
                     /locus_tag="VYO88_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1719627.1"
                     /translation="APAPAPKPEKPAEKPAPAPKPETPKTGWKQENGMWYFYNTDGSM
                     ATGWLQNNGSWYYLNANGAMATGWAKVNGLWYYLNSNGAMATGWLQYNDSWYYLNTNG
                     AMATGWLEYNGSWYYLNANGAMATGWLEYNGSWYYLNSNGAMATGWLQYNGSWYYLNA
                     NGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKANQWFKVSDKWYY
                     VNGLGALAVNTTVDGYTVNENGEWV"
     gene            1132..2253
                     /gene="mnmA"
                     /locus_tag="VYO88_001550"
     CDS             1132..2253
                     /gene="mnmA"
                     /locus_tag="VYO88_001550"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1719628.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2394..2849
                     /locus_tag="VYO88_001551"
     CDS             2394..2849
                     /locus_tag="VYO88_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1719629.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYIIGGA
                     IQVNESTEDAVVREVKEELGVKSQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHREE"
     gene            2859..4772
                     /gene="mnmG"
                     /locus_tag="VYO88_001552"
     CDS             2859..4772
                     /gene="mnmG"
                     /locus_tag="VYO88_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1719630.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNIKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4979..5071)
                     /locus_tag="VYO88_001553"
                     /pseudo
     CDS             complement(4979..5071)
                     /locus_tag="VYO88_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5125..6804)
                     /locus_tag="VYO88_001554"
     CDS             complement(5125..6804)
                     /locus_tag="VYO88_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1719631.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6806..7039)
                     /locus_tag="VYO88_001555"
     CDS             complement(6806..7039)
                     /locus_tag="VYO88_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1719632.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(7857..8009)
                     /gene="cibB"
                     /locus_tag="VYO88_001556"
     CDS             complement(7857..8009)
                     /gene="cibB"
                     /locus_tag="VYO88_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1719633.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(8011..8196)
                     /gene="cibA"
                     /locus_tag="VYO88_001557"
     CDS             complement(8011..8196)
                     /gene="cibA"
                     /locus_tag="VYO88_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1719634.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8374..9057
                     /gene="tsaB"
                     /locus_tag="VYO88_001558"
     CDS             8374..9057
                     /gene="tsaB"
                     /locus_tag="VYO88_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1719635.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENSKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SVESYIKRL"
     gene            9054..9491
                     /gene="rimI"
                     /locus_tag="VYO88_001559"
     CDS             9054..9491
                     /gene="rimI"
                     /locus_tag="VYO88_001559"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1719636.1"
                     /translation="MIEIKRIQQRPDLAQAIYAVMIAVYPINPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9481..10491
                     /gene="tsaD"
                     /locus_tag="VYO88_001560"
     CDS             9481..10491
                     /gene="tsaD"
                     /locus_tag="VYO88_001560"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1719637.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEVTDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWNLNAKPSLAFDT
                     ME"
     gene            complement(10531..11837)
                     /locus_tag="VYO88_001561"
                     /pseudo
     CDS             complement(10531..11837)
                     /locus_tag="VYO88_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(12229..12309)
                     /locus_tag="VYO88_001562"
     CDS             complement(12229..12309)
                     /locus_tag="VYO88_001562"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1719638.1"
                     /translation="MLPLPTYSPEYNPIEKIWAYIKNISE"
     gene            complement(12543..12869)
                     /locus_tag="VYO88_001563"
     CDS             complement(12543..12869)
                     /locus_tag="VYO88_001563"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719639.1"
                     /translation="MEKVDRDKLKIYIETHPDAYLTEIAAEFNCPPTTIHYALKAMGY
                     SLKKSRTYCEQDPEKVNRFLKELNHLSYLTPIYIYETGVETYFYLEYDRALSRQLVSL
                     EEDIII"
     gene            13106..14311
                     /locus_tag="VYO88_001564"
     CDS             13106..14311
                     /locus_tag="VYO88_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1719640.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRD
                     NFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLSEIIEH
                     RVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYD
                     ELLEKSSHG"
     gene            14304..>15186
                     /locus_tag="VYO88_001565"
     CDS             14304..>15186
                     /locus_tag="VYO88_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1719641.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKY"
BASE COUNT         4496 a         2827 c         3454 g         4409 t
ORIGIN      
        1 gccccagctc cggctcctaa accagaaaag ccagcagaaa aaccagctcc agctcctaaa
       61 ccagaaactc caaaaacagg ctggaaacaa gaaaatggta tgtggtactt ctacaatacg
      121 gatggttcaa tggcaacagg ctggctacaa aataatggct catggtacta cctcaacgct
      181 aatggtgcta tggcaacagg ttgggctaaa gtcaacggct tatggtatta cctcaacagc
      241 aatggcgcta tggcgacagg atggctccaa tacaatgatt catggtacta cctcaatact
      301 aatggtgcta tggcgacagg ttggctagaa tacaatggtt catggtacta cctcaacgct
      361 aatggtgcta tggcgacagg ttggctagaa tacaatggct catggtacta cctcaacagc
      421 aatggcgcta tggcgacagg ttggctccaa tacaatggtt catggtacta tctaaacgct
      481 aacggcgcta tggcaacagg ttgggctaaa gtcaacggtt catggtacta cctcaacgct
      541 aacggttcaa tggcaacagg ttgggtgaaa gatggagata cctggtacta tcttgaagca
      601 tcaggtgcta tgaaagcaaa ccaatggttc aaagtatcag ataaatggta ctatgtcaat
      661 ggcttaggtg cccttgcagt caacacaact gtagacggat atactgtcaa tgaaaacggt
      721 gaatgggttt aagccgatta aattaaatca tgttaagaac atttgacatt ttaattttga
      781 aacaaagata aggttcgatt gaatagattt atgttcgtat tctttaggta cctgtcttat
      841 gatttcagga aatgtcatta aaaaaacgac tccttttctc taacttggaa aatagattag
      901 agaaaatggg ttgttttatt tattatagtt atttgaatga agataagaag aagatatact
      961 cacatcattc acaaatctgt atattgacta taagttttaa aaaacaattt ttaagctctt
     1021 ccttgtcttc tctaactaag cgtgttataa tgaatactgc tcaagcgacc ttcaatcgtg
     1081 aagcacacac gaccttcaat cgtgaataaa cgaatagatg ggagacttac catgagtgat
     1141 aactctaaaa cacgtgttgt cgtggggatg agtggtggtg ttgattcgtc ggtgacggct
     1201 cttcttctca aggagcaggg ctacgatgtg atcggtatct tcatgaagaa ctgggatgac
     1261 acagatgaaa acggcgtctg tacggcgacc gaagattaca aggatgtggc tgcggtggca
     1321 gaccagattg gcattcccta ctactctgtc aattttgaaa aagagtactg ggaccgcgtt
     1381 tttgagtatt tcctagcgga ataccgtgca gggcgcacgc caaatccgga cgttatgtgc
     1441 aacaaggaaa tcaagtttaa ggcctttttg gactatgcca taaccttggg ggcagactat
     1501 gtagcgactg ggcattatgc tcgagtggcg cgtgatgagg acggcactgt tcacatgctt
     1561 cgtggcgtgg acaatggcaa ggaccagacc tatttcctca gccaactttc gcaagaacaa
     1621 cttcaaaaaa ccatgttccc actaggacat ttggaaaagc ctgaagttcg aaaactagca
     1681 gaagaagcag gcctttcgac tgctaagaag aaagactcga cagggatttg ctttatcgga
     1741 gaaaagaact ttaaaaactt tctcagcaac tacctgccag ctcagcctgg tcgtatgatg
     1801 actgtggatg gtcgtgatat gggcgagcat gctggtctga tgtactatac gattggtcag
     1861 cgtggcgggc ttggtatcgg tggacaacac ggcggtgaca atgccccttg gttcgttgtc
     1921 ggaaaagatc taagcaagaa tattctctat gtaggacaag gattctacca tgattcgctc
     1981 atgtcaacta gcctagaagc cagtcaagtc cactttactc gtgaaatgcc agaagagttt
     2041 acgctagaat gtacggctaa attccgttac cgtcagcctg actctaaggt gaccgtccat
     2101 gtcaaaggag acaaggcaga agttatcttt gcggaaccac aacgcgcgat tacaccagga
     2161 caggcagttg tcttttacga tggcgaagag tgtctaggtg gcggtttgat tgacaatgct
     2221 taccgcgatg gacaagtttg tcagtacatt tagattgaca aattttctca atttgctaca
     2281 ataataacag caatagaaat gatggtcaaa gctcatggat gttgcaggct tttttgtcct
     2341 gcacttcttt gtagttttga ctgtttttgt gtcgtttaag ggaaaggaca agaatgactc
     2401 aacaagactt tcggacaaaa gtagacaata cggtttttgg tgttcgggcg acagctttga
     2461 ttcttcaaaa tcgcaagctt ctagtcacca aagacaaggg caagtattac attatcggcg
     2521 gtgcgattca agtcaatgaa agcacggaag acgcggtagt ccgtgaagtg aaggaagaac
     2581 tgggtgttaa atctcaagct gggcagctag cttttgtggt tgaaaatcgt tttgaagtgg
     2641 acggcgtttc ctatcacaat atcgagtttc attatctggt ggatttgctg gaggatgccc
     2701 cattgaccat gcaggaagat gagaaaaggc agccctgtga gtggattgac ttggataagc
     2761 ttgaggatat ccagctagtt ccagcctttt taaaaacggc cctaccagat tgggaaggcc
     2821 aactaagaca cattcatcgt gaggaatagg agagaaacat gacttatcat tttactgaag
     2881 aatacgatat tattgtaatt ggtgcgggac acgctggggt tgaggcttcc ttggccgcta
     2941 gccgtatggg ctgtaaggtt ctacttgcga ctatcaatat tgaaatgctg gctttcatgc
     3001 cttgtaatcc ctctatcggt ggttctgcta aggggattgt cgtacgtgaa gtcgatgccc
     3061 tcggtggcga gatggccaag accattgaca agacttacat ccagatgaag atgctcaaca
     3121 cagggaaggg tcctgctgtt cgtgcccttc gtgcgcaggc tgataaggaa ctttactcta
     3181 aggaaatgcg caagacagtt gaaaatcaag aaaatctgac ccttcgtcaa accatgattg
     3241 atgagatttt ggtggaagat ggcaaggttg tcggtgtgcg tacagccacc catcaagaat
     3301 atgctgctaa ggctgttatt gtgacgacag ggactgctct ccgtggggaa attatcatcg
     3361 gagacctcaa gtactcatca ggtcctaacc acagcttggc ttctattaac ctagctgaca
     3421 atatcaagga actgggcctc gaaatcggtc gtttcaagac aggaacccct ccacgtgtca
     3481 aggcctcttc tatcaactac gacgtgacag aaatccagcc aggagacgaa gtgcctaatc
     3541 atttctcata cacttcacgt gatgaggatt atgtcaaaga tcaagtgcca tgctggttga
     3601 cctataccaa tggtaccagt catgagatta ttcaaaacaa cctccaccgt gcgcctatgt
     3661 ttacaggtgt ggtcaaggga gtggggcctc gttactgtcc gtcgattgaa gacaagattg
     3721 tgcgctttgc ggacaaggaa cgtcaccaac tcttccttga gccagaaggg cgcaatactg
     3781 aggaagtcta tgtgcaagga ctttcaacca gtctgcctga ggatgtccag cgtgacttgg
     3841 ttcattccat caaaggtttg gaaaatgcag agatgatgcg gacaggttat gctattgagt
     3901 atgatatggt cttgcctcat cagttgcgtg cgactttgga aaccaagaaa atctcaggtc
     3961 tcttcactgc tggtcagaca aatggaacat caggttatga agaagctgct ggccaaggga
     4021 ttatcgcggg tatcaatgcg gctctgaaaa tccaaggtaa acctgagttg attttgaagc
     4081 gcagtgatgg ttatataggg gtgatgattg atgacttagt gaccaaggga accattgaac
     4141 cttaccgtct cttgaccagt cgtgctgaat accgtctcat tcttcgccat gacaatgccg
     4201 atatgcgttt gacagagatg ggccgtgaga ttggccttgt ggatgatgaa cgctgggctc
     4261 gttttgaaat caagaaaaat caatttgata atgagatgaa acgcctagac agtatcaaac
     4321 tcaagccagt caaggaaacc aatgctaagg ttgaggaaat gggcttcaag ccgttgacag
     4381 atgcggtgac agccaaggaa ttccttcgcc gtccagaagt ttcttaccaa gatgtggtgg
     4441 ccttcatcgg accagctgca gaagacttgg atgacaagat tatcgaattg attgaaacag
     4501 aaatcaagta cgaaggctat atttccaaag ccatggatca ggttgccaag atgaaacgta
     4561 tggaagaaaa acgcattcca gccaatattg actgggatga cattgactct atcgcaacag
     4621 aagctcgtca gaagttcaaa ctcatcaatc cagaaaccat cggccaagcc agccgtattt
     4681 cgggagtaaa cccagcagat atttctattt tgatggtgta tctggaaggt aaaaatcgta
     4741 gtatttctaa aactcttcaa aaatcaaaat gatacgtcgt cggcttctta cgaatgagtt
     4801 caaagcttgg ctttgattca tctccaacct cccatagttc cccgaactat gggagctaac
     4861 tcaagttatg ctttcgctta gccttctagt ctgatttcga tttttattga tactcttcga
     4921 aaatctcttc aaaccgcgtc aacgtcgcct tgccgtaggt atggctactg acttcgtcag
     4981 ttctatctac aacctcaaag cagtgctttg agcaacctac ggctagcttc ctagtttgct
     5041 ctttgatttt cattgagtat gagttttaat ctcaaaagaa agcatagaga aaaacagctc
     5101 cgaggacggg gctgttttct tgctttattc ttcatctggt gtgaggatca tcgggatgat
     5161 gatcggttca cgttcggtat tttcatagag gaaggggcga atagcgttga caatggcacc
     5221 attgacagat tgcacgctag catccttatt tttcagtgcg atacgaatgg cattgaagag
     5281 gatacgctgg ctttggcgaa tcaagtcgcc agactctctc atgtagacaa agcctcggct
     5341 gaggatgtct ggaccagata gaatcatctg cgatttgaag tcaacagttg caactgccag
     5401 aacgacaccg tcttcagata gatcgcgacg atctttgagg acagctgcgc caatttcacc
     5461 gatacgattt ccatcgacat agatatcttg ggcgttgaaa tgacctgcga tacgagctga
     5521 gtcagcagta agggcaagca catcgccatt gctcatgata aagatattgt ccttctcaac
     5581 accagtatcc actgctagtc cagcgtggac tttttgcatg cggtattcac cgtggacagg
     5641 catgaagtat tttggcttaa tcaagcagag catgagtttt tgctcttgct gaccaccgtg
     5701 tccagatgta tggatattgt tcactttacc gtggataact tcgacaccag cttcagaaat
     5761 gatgttaatc agcttgttga cgctagtagt gtttccaggg atgggactag aagagaagat
     5821 aacggtatca cctggttgta attgtacttg acggtgggtt ccgttggcga tacgagagag
     5881 ggctgccata ggctcaccct gactacctgt acagaggata agaacttctc ctgcaggata
     5941 atctttgatt tcatttggct cgataaaggt tcccttagga gctttgatgt agccaagatc
     6001 gattccgttg acaatggcct tttccataga acgaccaaag accgcaatct tgcgtccagt
     6061 cttaacagca gcttctgttg cctgctggag acggaagata tttgaggcaa aggatgcaaa
     6121 gatgatacgt ccttcaatac cttggataat cttcataatg gactgaccaa cgactttttc
     6181 agagttggta aaggttggta cttccgcatt tgtcgagtca gacaggagac agagcacgcc
     6241 ttcttcacca agcgcagcca tacgatgcaa gtccgcaggt tctccaactg gagtaaagtc
     6301 gaacttaaag tcacccgtac agacgatttt cccttgagga gtatgaatga caatccccaa
     6361 aggctctgga atagagtgag tcgttctaaa gaaagttgcc ttgagatttt taaaggtcaa
     6421 ctcggtgttg tggttgattt cgtaaagttt ggcgttgcgc aagaggccgt gttcttcgag
     6481 tttcccacgg atcaaagcca aggcaagcgg tccagcgtag atagggacat ttgcttgctt
     6541 gagtaggaac ggaatcccac caatgtggtc ctcgtgtccg tgtgtgatta aaacagcctt
     6601 gacgcggtcg atattgtcca cgatgtaaga gtagtcagga atgacatagt cgataccaag
     6661 caagtcatct tctgggaatt taatcccagc atcgacgatg ataatctcgt cttggtattc
     6721 aattccgtaa gtgtttttcc cgatttctcc cagaccaccg atggcaaaaa cgccgacttc
     6781 ttcaggttta agagtatagg ccatattaga actccgtgat ttcgaaggcg ccagtttctt
     6841 tttcgtaatc gagcaatttg tcagacaaga gttcgatata ttcgatattg tactctgggc
     6901 gattttcttc gacaagttgg cgagcagtga tgcgaccctc aagttctgag ctggcatcga
     6961 tgtctaggta aagtgcgcgt gttgtttcac ggcgtgggct acgttctttt gtttcttgat
     7021 aaaaaacttt gtaaatcata tagttccttt ctatttacag gtcagcttat tccaaacttt
     7081 tagcagagat ttgcttgatt tcattccatt ttgtgtctag attgaccttg attcgttaca
     7141 attatttcaa ttataccaca aaatgaaaaa ttagtaaaag acggaaacga gaaagttagg
     7201 ggacgatttc ttcggtaagc gtttgcaaaa ataaagaaaa tgtgttatgt tgataacgga
     7261 agtgaagttt attacttgtc ataattccat atagatttta agtcaaggag gttgccctat
     7321 gtataactta tttgcttttg ctatcggagt tcgtttgtta gcttttatcg tttttgttgc
     7381 ttgcgtttat ggaggaaatc ttctatttgc caaactggaa cgatgacaaa ccaagttctt
     7441 gtggaaaatt acctttgtga ctctctactc gctttttctc ctcctcgtga cctatgtcgt
     7501 ttggtttgta ttttactttg gattaaatgc ttagatgccc tgcttatgct ggggtttttt
     7561 gtttggggat gtagagatag tagatttacg acacgaaaat tccaccccat ctatcaagat
     7621 gaggtggtct ttgcattttt ataaaatgac atgacaatgg aattttcaaa gcttattatt
     7681 tttatgggag tcattgttct gctcaaaaat agagttgaag cataaaaata aaacaataca
     7741 aacagataaa tcgaatggta aagggatagt agtaatgttc aaatcattga gaatgctgag
     7801 caaactgtaa gagatgaaga caataaaatt tatccttcta aaaatgtgtt tcttatctag
     7861 catgacttac caaacttttt acgaaggtct tttccaatgg tataacctgc cataaataaa
     7921 gcgataccaa cacctacacc aaagccaccc ttgatttctt gcaattcctt attagaaatt
     7981 tcacgatagt tgttcaaatt tttcatcata ttaatctcct cctaaaaaat aaccagctgc
     8041 caaaccagaa cctataagtg ctgttccacc tgcaatagcc ttccaagata ctgctactcc
     8101 aaagataacc aagggagcga gaccgccatc aatatctgat aattcatttt cagataagga
     8161 taaaaattga ttgtcaagaa tgtcaaaatt tgtcattgaa ctttcctcct tttttcttgt
     8221 tcacttttat attcggaaaa gaaaaggaaa agtgagcatt tttttaaatt atttttagtt
     8281 aagtgagggc actcttgtct gggggcaaag aaaattccca tgtgccagct tttgtagtat
     8341 aatagtaagc agacaaaaag ataggaatgt gttatgaaag tattagcttt tgatacgtcc
     8401 agcaaggctc tttctctcgc tattttagag gacaagcagg ttcttgccga gacgacgatt
     8461 aatattaaga aaaatcacag tattactctt atgcctgcca tagatttttt gatggcaagt
     8521 ttggattgga cacccaagga tttggaccga atcgtggtag ctgaagggcc gggtagctat
     8581 acaggcttgc gaattgcggt agcaactgct aagaccttag ctcacaccct gaacatcgag
     8641 ttggttggta tgtcgagtct cttggctctg gtgccccacc aacaagaagg tttgtttgtc
     8701 cccttgatgg atgcgcgtcg caataatgtt tatgcaggat tttatgaaaa ttccaaacct
     8761 gtcatggcag aagcacatct gccttttgag cgagtcattg agctaatcaa gggcgctagt
     8821 caggtaacct ttgtcggaga agttggcccc tttgttgagc agattcaaaa acacttgcca
     8881 aggactgatt acaaagaaac attgccaaat gcagctaatc tagctctatg ggcctgggac
     8941 aaggaagcag actccttgca tgattttgtg ccgaactacc tcaagcgtgt cgaagctgag
     9001 gaaaactggc tcaagaatca caccgagtct gtcgagtctt acattaaacg cctatgatag
     9061 aaatcaaacg aatccaacag cgacctgact tggctcaagc catctacgct gttatgatag
     9121 ctgtttaccc aatcaaccct tggacgctgg aacaaatcca agcagatctg tcccaagacc
     9181 agacttggta tgcattggct tatgatgggg cagaagtgat tggatttcta gctgtgcagg
     9241 agaatctttt tgaagcagaa gtcctgcaaa tcgctgtcaa aggagcttat cagggtcagg
     9301 gaattgcgtc agccttgttt gctcaattgc cgacagacaa ggaaattttc ctcgaagtca
     9361 gacagtcaaa tcaacgagcg caagcatttt acaagaaaga aaagatggca gttatcgctg
     9421 agcgaaaggc ctactaccat gacccagtcg aggacgccat tatcatgaag agagaaatag
     9481 atgaaggata gatatatttt agcatttgag acatcctgtg atgagaccag tgtcgccgtc
     9541 ttgaaaaacg acgatgagct cttgtccaat gtcattgcta gtcaaattga gagtcacaaa
     9601 cgttttggtg gcgtagtgcc cgaagtagcc agtcgtcacc atgtcgaggt cattacagcc
     9661 tgtatcgagg aggcattggc agaagcaggg attaccgaag aggacgtgac agctgttgcg
     9721 gttacctacg gaccaggctt ggtcggagcc ttgctagttg gtttgtcagc tgccaaggcc
     9781 tttgcttggg ctcacggact tccactgatt cctgttaatc acatggctgg gcacctcatg
     9841 gcagctcaga gtgtggagcc tttggagttt cccttgctag cccttttagt cagtggtggg
     9901 cacacagagt tggtctatgt ttctgaggct ggcgattaca agattgttgg ggaaacgcga
     9961 gatgacgcgg ttggtgaggc ctatgataag gtcggtcgtg tcatgggctt gacctatcct
    10021 gcaggtcgtg agattgacga gctggctcat caggggcagg atatttatga tttcccccgt
    10081 gccatgatta aggaagataa tctggagttc tccttctcag gtttgaaatc tgcctttatc
    10141 aatcttcatc acaatgccga gcaaaaggga gaaagtctgt ctacagagga tttgtgtgct
    10201 tccttccaag cagctgtact ggatattctc atggcaaaaa ccaagaaggc tttggagaaa
    10261 tatcctgtta aaaccctggt tgtggcaggt ggtgtggcag ccaataaagg tctcagagaa
    10321 cgcctagcag ccgaggttac agatgtcaag gtcatcattc cacctctgcg cctctgcgga
    10381 gacaatgcag gtatgattgc ttatgccagt gtcagcgagt ggaacaaaga aaacttcgca
    10441 ggctggaacc tcaatgccaa accaagtctt gcctttgata ccatggaata aagagtggct
    10501 ctttgtcaag tgtagtgggt aggcgaaaag ctacaatctg gagagtacga aattcgtact
    10561 ctcttttttg atgttcaaag tcatcaaaat ccgtttttta aaattgttaa agttccggaa
    10621 accaaaggct ttgcgcttga taaccttaat caaattattg gtcgcttcaa gtttagcgtt
    10681 ggaataaggc agcttaagtg cgttgataat cttatctcta tcccttaaaa aagtccaaaa
    10741 gaccgtttga aaaagcggat gaaccgttgg cagttcttgc tcaatcaatc caaagaaatg
    10801 gtcggcattc ttctcttgaa aatgaaagag caggagttga tagagttcgt agtgaacctg
    10861 taatccctca gagtaagaaa gcagcttatc tcgtacttcc cgatgggtta agtgcattcg
    10921 aaacgtgggc tgatagaatc gtttctgaca gagcttgaag ctatcctggt gtagtaaatc
    10981 agtccagtgg actgatttag cccgagccta gaaacgaaaa agcgagggtt ccaaaagcgc
    11041 ttgagcgccc gatactccaa ggattttcgg tcaaattggt tcatgatttg gattcgtact
    11101 cggttcatag ctcggctcag atgttagaca atgtggaagc ggtcaagaac aatcttcgcc
    11161 tttggaaaga gttgcttagc gagccgataa taagggctgt acatgtccat ggtgatgacc
    11221 tcgaccagct cccgaacctc tctctgatag cgttggaaat ggtttcgaat caccgcatga
    11281 gttcgcccgt ctaaaattgc gaggatggat ttggactcaa aatcttgggc aatgaagctc
    11341 attttgctct ttttgaagct atactcatcc caactcataa cttttggcaa cttggtccaa
    11401 tcggtttcaa acttaaattc cctcagtttt cggatgacgg tggaagttga gcccgccaat
    11461 ctgtgggcaa tctcagtcat agactgcttt tcaaggagga gctgagcgat tttttgtctc
    11521 accatgttgg aaatctggca atttttcttg acaatggatg tttgagaaac gaccacctta
    11581 aggcaattct tgcactgaaa gcggcgcttt ttgagatgca gtaccgtggg taaaccctga
    11641 cagtcgagaa gcggaatttt agaggctttc tggaagtcgt atttgatcat cttcccttga
    11701 caatgaggac aaggaggagc gggggaatcc aactttgcct gaacgactag atgggtttgg
    11761 tatttcagaa cagacaagat tttgatattt ttgtcttcca atccgagcaa atctgtggta
    11821 ttcttaagtt gttccatatg aaccctttct aatgagttgg ttagacgctt ttcattatag
    11881 gtcatatggg gctttttttc tacaagaaac gaccctataa ttcctggggt gggattaccc
    11941 actacagaaa ttatagagcc aaaacattcc aaagtcttgt ctgactctgg aatgttttct
    12001 gttcacagtt gttttgtaac tgcctaataa gtaaccgcgc tataacgagg tatctaccga
    12061 gattgtcaat tctccagtat actgttataa aaaacaaaac tggaggattt ttttatgtcc
    12121 ccccatcgtc ccatcgactg ttccgtagct gcccaataac ggagtatagt cgtctgaaac
    12181 aagaatagga caaaagtgcc tcaagaaaag catcgtaatt tgacaatatt attctgagat
    12241 gtttttgatg taagcccata ttttctcaat gggattatac tcgggtgaat aggtaggaag
    12301 tggtaacagt ctatgccctg ctccttacac atgttcattc tgtgaaacct tgcattgtcc
    12361 ataatgataa gggatggtgt atctaaagta ggtagtaaga atttttggaa gcaagcttcg
    12421 aaaaagtcac tcgtcatcgt atctttatag gtcatcggag ccatagtata ttgaaacaaa
    12481 aagggcatta gtacttctat aacagtatcg caatctctgg tgtgcgttgt ctcgatctta
    12541 attcaaataa ttatatcttc ttccagagag actaactgcc tgctcaaggc tcgatcatat
    12601 tcgagataaa aataggtctc aacccctgtc tcataaatat aaataggagt caggtagctt
    12661 aagtgattca attctttaag gaaccgattt actttttctg ggtcttgttc gcagtaggta
    12721 cggctctttt ttagactata tcccatagcc tttagagcgt aatgaatagt tgttggagga
    12781 cagttgaatt cagcagctat ttcagtcaaa taagcatcgg gatgagtttc aatatagatc
    12841 tttaatttat ctctatcaac tttttcaatt aatagtggaa gttttcttaa agttagtgta
    12901 ttgaaacgtt tttatacagt gctaaaattt gaagtgtagt gcagatgtat ttgtaatagt
    12961 attatagcaa ttctttggag aaggtcgaga caagagaaaa taggtatctt tgagatataa
    13021 gcatgattta ctataaaatt attgagttat tcataaaaat ttctctatca aatatcataa
    13081 tgcgtcgttt aaggagatgg ttacaatgca atatagttgt ggaaaaataa atattaatat
    13141 ccctgatgga tatggagaca ttaaggatat agtgttttcg gctcatatta tagttaggta
    13201 taataatgga cattgtggag gtatagatcc gcatataatt ggactttgta aaaagcagat
    13261 cagaaggatg tctctatatc ctattttgat aatcgtatct agagattcaa aggttattga
    13321 tgattataaa aatttagata ttgcctatgt tgattgtact caatgttcaa ataattttga
    13381 aactgcctta cacgttaaaa atattttaaa attattaaaa atccaactta tacactgtca
    13441 tggctactca actaattatt ttttatatat gttaaaaaaa cttgacaaga atggatttgg
    13501 aaaggttaag acagtgataa catgccatgg atgggttgaa tataacttaa aaaagaaatt
    13561 cttgacttat tttgattttt ggacatattc tatgggagat gcttttattt gtgtatctga
    13621 aactatgaaa aaaagattgg agagtataat aaaaaataag aagatagttg caataaataa
    13681 cggaattaat gtatcaaata gcgatttaga tgtagtaggt gttcaagact ttaaaaaaga
    13741 attttgtatt ccaaataaca aaaaaatcat ttgttatgtt ggaaggttgg atccagaaaa
    13801 aaggccggat agattccttg aatttgcaga aaaattattt ttagtcagag aagatgtgat
    13861 ttttattatg gctggaaatg gtagtatgtg ggctgctttg aaagaaaaaa tttgccattt
    13921 gaaatgtaga gataatttca ggttacttgg tgaaatctat ccagctacta tagtttacca
    13981 aatatcggat ttattgtata ttccttctga tacagaagga atacctatgt gtgttttaga
    14041 gtcaatgtca caaggaactc cggttttagc tagtaatgtt ggcgggttaa gtgaaattat
    14101 tgaacatagg gttgatggat ttttatttga gaaggaagat gttgagggag tgtgtgcttg
    14161 tgctaatttt ttactcaatg attctgagta tttgaaatat ataggtgaga atagtaaatc
    14221 aaaaataaga aaacattttt ctgtgcaaaa aatgtttgta gaaaccatga gagtatatga
    14281 tgaattatta gagaagagta gtcatggata ggaatataga tcaagaatta gtaagtatta
    14341 taataccaac acataatagg tatgaatctc tgattagagc tgtgaaaagt tgtttacatc
    14401 aaagttataa aaatatcgaa gttataatta ttgatgataa ttatagtaat gtaaatttaa
    14461 gaaataaaat tatccatcaa tttggctata ccaatcatag aattaagtta attttaagta
    14521 atgaagattt aggtgcaact aatgccagaa acataggtat caaaaattct agaggtaagt
    14581 atatatcatt tttagacgat gatgatgaat atatgccaga tcgaatttta aagttgatgg
    14641 cttgttttaa aaagagtaga atgaagaatt tagctttagt ttatagttat ggaataataa
    14701 tttatccaaa tggtacacga gaagaggaga agaccgattt tgttggaaat cccttgtttg
    14761 ttcaaatggt tcacaatata gcaggtacgt cattttggtt gtgtaaaaaa gaggtgctag
    14821 aattaattaa tggttttgag aaaatagatt cacatcagga cggtgttgtt ttattaaaac
    14881 tacttgctca aggataccaa attgatatag tgcgagaatt cttggtgaat tactacgctc
    14941 acagtaaaga aaacggtatc actggagtga cacaaaaaac aattaatgca gatgaagaat
    15001 attataatta ctgtaggaaa tattttaatt tattgagttt caacgagaga atattggtta
    15061 caaagaaata ttattcttta aacataaagc ggttactatt aataggagac aaatgcaagg
    15121 ctttaaaagt aatcaagaag gcaagagaag aaaaaatttt taacgaattt ctttttttga
    15181 aatata
//
LOCUS       DAVLZS010000044        13977 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLZS010000044 DAVLZS010000000
VERSION     DAVLZS010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13977
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.044"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(105..542)
                     /locus_tag="VYO88_001566"
     CDS             complement(105..542)
                     /locus_tag="VYO88_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1719642.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWVQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(627..3260)
                     /gene="polA"
                     /locus_tag="VYO88_001567"
     CDS             complement(627..3260)
                     /gene="polA"
                     /locus_tag="VYO88_001567"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1719643.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3513..3866
                     /locus_tag="VYO88_001568"
     CDS             3513..3866
                     /locus_tag="VYO88_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1719644.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQV
                     NQNLEKIRQREGDTH"
     gene            4081..4197
                     /locus_tag="VYO88_001569"
     CDS             4081..4197
                     /locus_tag="VYO88_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1719645.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4190..4423
                     /locus_tag="VYO88_001570"
     CDS             4190..4423
                     /locus_tag="VYO88_001570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719646.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            4550..4828
                     /locus_tag="VYO88_001571"
                     /pseudo
     CDS             4550..4828
                     /locus_tag="VYO88_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4965..5933)
                     /locus_tag="VYO88_001572"
     CDS             complement(4965..5933)
                     /locus_tag="VYO88_001572"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1719647.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(6078..6893)
                     /locus_tag="VYO88_001573"
     CDS             complement(6078..6893)
                     /locus_tag="VYO88_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1719648.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLLGWLSSFANTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKFLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(6918..7415)
                     /locus_tag="VYO88_001574"
     CDS             complement(6918..7415)
                     /locus_tag="VYO88_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1719649.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     AVVEL"
     gene            complement(7488..8849)
                     /gene="radA"
                     /locus_tag="VYO88_001575"
     CDS             complement(7488..8849)
                     /gene="radA"
                     /locus_tag="VYO88_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1719650.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(8863..9378)
                     /locus_tag="VYO88_001576"
     CDS             complement(8863..9378)
                     /locus_tag="VYO88_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1719651.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGEMLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(9380..9823)
                     /locus_tag="VYO88_001577"
     CDS             complement(9380..9823)
                     /locus_tag="VYO88_001577"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1719652.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            complement(9880..9977)
                     /gene="ffs"
                     /locus_tag="VYO88_001578"
     ncRNA           complement(9880..9977)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYO88_001578"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(10010..10477)
                     /locus_tag="VYO88_001579"
     CDS             complement(10010..10477)
                     /locus_tag="VYO88_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1719653.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(10678..11964)
                     /locus_tag="VYO88_001580"
     CDS             complement(10678..11964)
                     /locus_tag="VYO88_001580"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1719654.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(12195..12431)
                     /locus_tag="VYO88_001581"
     CDS             complement(12195..12431)
                     /locus_tag="VYO88_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1719655.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            12697..13494
                     /locus_tag="VYO88_001582"
                     /pseudo
     CDS             12697..13494
                     /locus_tag="VYO88_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13529..13738)
                     /locus_tag="VYO88_001583"
                     /pseudo
     CDS             complement(13529..13738)
                     /locus_tag="VYO88_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13904..13977)
                     /locus_tag="VYO88_001584"
     tRNA            complement(13904..13977)
                     /locus_tag="VYO88_001584"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13941..13943),aa:Asn,seq:gtt)
BASE COUNT         4425 a         3330 c         2345 g         3877 t
ORIGIN      
        1 caacctcaaa acagtgtttt gagcagcccg cggctagttt cctagtttgc tctttgattt
       61 tcattgagta taacacaaaa ggtagcccat cagctacctt tttcttatgc ttcctcaatc
      121 aagcgagtat gttctctctt gatacagcga ttcatcacga tatcatcaca tccaccatca
      181 cgcaaaatct ctttcgcttc taaactttca agtcctagct gtacccaaaa aatcttggca
      241 tcagctttga gaaaatcacg cgccacatcg ggcagaaatt cactgcgacg ataaacattg
      301 acaatatcta caggaaaagg aatttcagcg aggctagcat aagccttttc acccaagatt
      361 tcgccacctg ccgccttggg attgactggg atgattttat agccccgagc ctgcatttcc
      421 tttgttactc gattgctggt tgtttcttca cggtcagaca aacccaccac agcaagggtt
      481 ttactcgttg cgagatactg acgaatcacg ccatcacttg gattgataaa ttcttgactc
      541 atagaaatcc tcctttttca tcagtatagc acattttgaa aaggtttgca gaattatact
      601 acaaaaaagg aggactagcc ccctttttat ttagcctcgt accaggttgc cccttcattc
      661 tcatctgcga taagaggaac actgagttga atggcttctt ccatggtttg tttcaccaat
      721 tttttcatct ctaccaattc agatttaggc acttcaagga cgatttcatc gtgcacttgt
      781 aacagcatct tagtctgata accacctgca accaaggctt tatccagctg aatcatggca
      841 atcttgagaa tatctgctgc cgaaccctgg ataggtgagt tgatagcagt tcgctccgca
      901 aaaccacgaa tattgaagtt gcgcgaattg atatctggca actcacggcg acgcttaaag
      961 agggtctcta catagccctt atcacgcgcc tcccgcacca cttcatccat gtagttttta
     1021 atacctggaa aacgttcaaa gtaggtatca atgtaggctt tggcttcctt acgactaatt
     1081 cccaaattat tagacaagcc aaagtctgaa atcccataaa ccactccaaa gttaactgcc
     1141 ttggcattgc gacggtcgtt tgcagtcaca tcatcaggac gctcaatgcc aaagacccgc
     1201 atggctgtcg aagtatggat atctgccccc tcttggaagg ccttaatcaa gtgctcatcc
     1261 ttagaaatat gcgccaaaac gcgcaattca atctgtgaat agtcagagct gagtagcaca
     1321 ctatcctccc actctggcac aaaagccttc cgaatcaagc gcccctgttc caatcgggca
     1381 ggaatatttt gcaagtttgg atccacacta gacaaacgcc cggtctgggt caaatcctgc
     1441 acatagcgag tatgaatctt tccatcagcc aaaatccagt cctgcaagcc aattacataa
     1501 gtagattgaa tcttagcaat ttgacggtaa tccaggattt tcttaacaat cggagcaata
     1561 ggagcgagac gctccaaaac atccactgct gtcgaataac ctgtcttggt tttcttagtg
     1621 tattctagag gaagtcccaa tttctcaaag agaagcacgc ccaactgctt aggcgagttg
     1681 acattaaact cctcaccagc cagctcgtaa atctcttgag tcagtttttc aatgacaagc
     1741 tcattttcag cctgcatctc aagcaaggtc tctttcttga ccataatccc agcaatttcc
     1801 atcttggcaa ggacaaaagc cagaggttgc tccatatcat aaagaagctc taattgccca
     1861 ttttcgctga gtttttcaag taaaataggc tctgtttcta ccaaaacagc aagtttacaa
     1921 gctaagtgtt ccaagaattt ctcacgttca ggaatggcct ttttaacacc cttaccgtag
     1981 aaagtttcat catcaaccaa gtaagtctga ccataaagac tagcgatggt cgcaatttca
     2041 ttgtcctcca cagtcgaaag gaggtattta gccaaacgga tgtcaaaagc aggcgcctgc
     2101 aaatccacac caaaacgttg caaaagaact ttaaccttct taaagtcata aactctcaga
     2161 gatgtttttt ctaagaaatc cttgaaaatc gggtcttgca acagctcaag cttgtctgtg
     2221 gcatagagct tatccccaca agaccaggca aatccaacca aattatccgt atggtaattc
     2281 tcaccaaaaa gctcaaagtg gaagatagac tcttcactca gcatatcttg actgatttgg
     2341 tcaacaatag taaaatccaa actctcagac acatcagctg acgacacatt taaagcctgc
     2401 tttagctgtt tgaagcccat ctcatcgtag aatttcccaa gattttcaac atctggacca
     2461 ctatagacca agtcctctaa accaatcgca atcggtgcct tggtatcaat ggtcgctagt
     2521 gttttagata aaaaggcctg ttccttgtca ttgatgagat tttccttcat cttagaagtc
     2581 ttcattccat caatattttc ataaatcccc tcaagcgaac catgctccag caagagctta
     2641 atacccgtct tttcaccgac tttggtcacc ccagggatat tatccgactt atcacccatg
     2701 agcgccttga gatcgataaa ctgagctggt gtgaggccca tttcttccat gaggtaatct
     2761 ggcgtaaagg cctcaaactc agccacacct ttcttggaaa tttcaaccac cgtatgctca
     2821 tccgtcagct gaatcaaatc cttgtcccca ctgacaatgg taatatcaaa accatcctgc
     2881 tctgctagct tatccagcgt cccaatgatg tcatccgcct catactgagc cagctcatag
     2941 tgacgaatcc ccatatgatc cagcaactca cgaatgaaag gaaattgctc acgaaactca
     3001 tcaggagtct tggcccgacc acccttatag tccgcataca tctctgtccg gaaggtcgtc
     3061 tttcccgcat caaaagccac caaaatatga ctcggctcaa cccgctccaa caaatgactc
     3121 aacatcaact gaaaaccata aatcgcattg gtatgcaaac cagccgcatt cttaaaacgg
     3181 tccaactgct gatacagcgc aaaaaacgcc cgaaaagcta cagaagaccc atcaatcaat
     3241 aataattttt tcttatccat acacccatta taaaggaaag aatcaaaaaa taccattggg
     3301 aagagctaga gcaagtattt ttcaaacttt ttccgaataa atagatagag ccagagaatt
     3361 tagtaaacct agatttaaaa atgtgctata atatagtata ttgaatctat aatagtacac
     3421 cttgactgct aaaatatttc tataaattaa tttgactttc ctgatagagt tgttcacatc
     3481 ttatttcaat tcactataga aggaggaaaa ggatgattct cagacatctg ggaattagcc
     3541 cgaccaatga cttggttgct aagaaaatat tcagcaatcc agaaatcact tgtcaattta
     3601 ttcgcgatat gctggacttg ccagcaaaaa atgtgaccat tttggaggga agcgatattc
     3661 acgtattact ctccatgcct tactcggtgc aggattttta taccagtata gacgtcttgg
     3721 cggagttgga taacggtact caagtaatta ttgagattca agtccatcat cagaattttt
     3781 tcatcaatca cttgtggact tacctgtgca gtcaggttaa tcaaaatctt gaaaaaattc
     3841 gtcagcgaga aggtgatact cactagagct acaaacacat cgctcctgtt tacgccattg
     3901 ctatcgtgga tagtaattat ttctcagatg acctggcttt tcatagcttt agtatgcgcg
     3961 aagacacaac aggtgaggta ttggcgatta ccaacaatgg acaggaaaac catctggtta
     4021 agatggcatt cttggaatta aaaaatacag agaaaccagc aaagacaagg ttcgcaagcc
     4081 atggttggag tttttcggca acaagccctt tacccagcaa ccgcaacgag ccattaccca
     4141 agcaaatcaa ctgctggact acaagagctg gtccgaggag gacaggaaaa tgtttagtca
     4201 actacatatg cgagaagaac aagtcttgtt agcacaggac tatgccttgg aaactgctag
     4261 ggctgaaggc cttgaacaag gactagagcg tgggaaagtt gaaggaaggg cagaaaggaa
     4321 actttttgcc ttcctagaca tagtacgcca aggtcttctg acttctgagg ttgccagcca
     4381 gcaattaggt atgtcagtat ctgaatttga ggcactgttg taaaatggct ccataatatc
     4441 catagtgggt aaatccccta tggatattat ggagcctatt ttgtgtagaa aaaaagtccc
     4501 atatgaccta taatgaaaag cgacaaaaca actcattaga aagaatcatg tggaacaatt
     4561 acattttatc acaaaattac tagacattaa agaccctaat gtccagattt taaacatcat
     4621 caataaggat acacacaagg aaatcatcgc caaactggac tacgacgccc catcttgccc
     4681 tgagtgcgga aaccaattga agaaatatga ctttcaaaaa ccttctaaaa ttccttatct
     4741 tgaaacgact ggtatgccta ctagaattct ccttagaaag cgtcgattca agtgctatca
     4801 ctgttcaaaa atgatggtcg ctgaaactta tgatgacgta cagtcatatt tcttctcttt
     4861 ttattatatc acagttttaa atctagcttt actagattca ccgctactat ctatttattc
     4921 ggaaaaaaga cgaaaaaacc tgagaatcat ctcaggcttg gtcattaaat ttttttctca
     4981 atatcgaaaa gtggagaaag tggtcgtttt tcatgaatac gtacgatagc atcccctagg
     5041 agatgagcga ttgaaatctg ctcaatctta tcaatcaaac gctcttctgg cagatagatg
     5101 gtatccaaaa caaccaattt cttaatagct gatttttgga tattgtccgt agcaggacca
     5161 gaaagaactg ggtgcgtaca gcttgcatag acttcaacag caccagcttc cgcaagagca
     5221 tctgccgcat gacaaatcgt tccagcggta tcaatcatat catcaatcaa gatacaagtc
     5281 ttgccttcaa ccttaccgat gatgttcata acttcactag tattcatctt atcaacgcta
     5341 cgacgtttat caataatagc gatagatgtt ttcaaaaatt ctgccaactt acgagcacga
     5401 gtcacccctc catggtccgg gctgacaacc acatagtcag aaccaaccat accacgacgc
     5461 tcaaaataat ctgcaatcag aggagcaccc atcaaatgat ccacaggaat atcaaagaat
     5521 ccttgaattt gcgcagcatg caagtcgatg gtcaataaac gatccactcc agctacttca
     5581 agcatatttg cgacaagttt tgaagtgatt ggctcacgcg ctctcgcctt tctatcctga
     5641 cgtgcatacc catagtaagg catgacaaca ttgacagatt ctgcactcgc acgcttcaaa
     5701 gcatctacca taatcaaaat ttcaagcaga ttgtcattta caggcgaact agttgattgt
     5761 aggataaaga cgtgtttccc acggattgat tcttcaatgt tgacctgaat ctctccatct
     5821 gaaaattggc gaacacttga tttccccaac tctatcccaa tctcctgcgc tacacgttct
     5881 gccaattctt tattagaaga aagggcaaac agctttaaat cagaaaaaga catgatttcc
     5941 tccggtatat atgtataact tgtgcttttc acaagatttt ccatctacca ttgtagcgct
     6001 ttttgcacta tttttcaatc aaaaataaaa gaagggcacc atatttgtac ccttgcatca
     6061 ttcttttgaa aaatattcta ggtcatcaac tcattgtgtt tctcaacaaa gcaataagca
     6121 tgataaaaac catagagagc aatagccgta accactggaa tcgctaaagg caactctgtt
     6181 tccaactcca caaaaggaga gttaaacaag aagtgagttc ccaaggctaa acctagaaaa
     6241 ataaggccct gtttcttgcc aaccttctgt cctttatagg ctctgtaaag caagtaaaca
     6301 cctactacag ctagacctga aaaagtccag tgagaggcaa ttcctgagat gatacgctct
     6361 aaaattcgcg aaatagtaaa gtcaaagccc tctggcaaat ccgtacgaat ataaccaata
     6421 tcctcaatca tttggaatcc caaaccggaa gcaattccaa gtaaaaacaa aaattttaat
     6481 tttcgcacag gaatcaaagc caaaacaaaa acaagtggca ataatttcaa gggttcttct
     6541 accaaaggag ccacaatagc actttcaaag gcatttaaaa atggactatc tgggaaaaga
     6601 acccccagta aatcatggat ataagtatta gcaaaactag acaaccagcc taaaaggaac
     6661 atccctccca ataaagacag aatcaaaacc ttctttggca attcccattt tttcccaata
     6721 cggaagagaa aataaagagc cggaatcatg taaaagagag ctagaaagat agaaactccc
     6781 attagtccat attccgcacc tgacctcgaa ccgtccgtat agtagatggt ttcatactgt
     6841 aaaccaatac atagcaataa aataaaaata aataaaatac tgcttttctt catacacttt
     6901 ctttctaaat gaagtattta taattctacg actgccatac ttcctgtatc aacattgtaa
     6961 atggcaccag agataatgac atcgtctggt attaggggag actcgataag cagttgcata
     7021 tcctcgcgta cactctcttc tatatcttgg aagggcaaga agtcctggtc tgacacatct
     7081 acacctaatt cctcttttaa atactcctga aaaggttcat tttcaaaggt ctgagcacca
     7141 cagtctgtat ggtgcaatac cacaatctct cttgtcccca tttgttgctg ggaaataact
     7201 agcgaacgaa tcatgtcttc agtcactcga ccacctgcat tccgcaagat atgagcatcc
     7261 ccaagtgcca agcccagagc ttgcgcaacg tgcagacgag agtccataca ggtcacaata
     7321 gctactcttg ttttgggttt aagtggcaga tttaactgcc catgtagggc aacataagcc
     7381 tgattagctt gcataaactg ttcaaaatac gacacgattc cctccttgaa aatttgatag
     7441 tcaaatattt ctcctatctt atcattttta agagaatttg tcacggatta tgcaaagacc
     7501 tttttcaaaa cttcctgaat cgttgtcacg ccaatgacct gaatttcctt aggcagagtg
     7561 attcctgtca aggaattctt aggtacataa atcttagtaa agcccagttt agcagcttcg
     7621 ttgatgcgtt gctcaatacg attcacgcgc cgaatctctc ctgtcaagcc cagttctccg
     7681 acaaaacatt cctgaggatt agttggcttg tctttgtagc tcgaagcaat agcaactgca
     7741 acagccaagt caatcgcagg ttcatccaat ttaacaccac cagcagattt gagataggca
     7801 tcctgatttt gcaagagaag ccctgcccgt ttttccaaaa cagccataat caagctagca
     7861 cggttaaaat caagtcctgt cgtagtacgc ttggcatttc caaacatggt cggtgttacc
     7921 aaagcctgaa cctccgccaa aatcggacgc gtcccttcca tggttacaac gatggaggaa
     7981 ccagtcgccc catccaaacg ctcttctagg aaaacttgac tcggattgag tacctcaacc
     8041 aagccgcccg actgcatctc aaaaatccca atctcattag tggaaccaaa acgatttttg
     8101 accgctctca aaatacgaaa ggtgtggtga cgctcccctt caaagtaaag caccgtatcc
     8161 accatatgct ccaacatacg aggcccagcc aaggttcctt ctttggtcac atgacctacg
     8221 ataaagatgg caatgttatt ggtcttggcc aactgcatga gttcagcggt cacttcacgc
     8281 acctgagaaa cagacccctg cacccctgaa atctcaggag acatgatggt ctggatggaa
     8341 tcaataatga gaaagtctgg ctggatacgc tccacttctg cacgaacact ctgcatattg
     8401 gtctctgcat agagataaaa ctcactatca atatcaccta agcgctctgc acgtagttta
     8461 atctgctggg cagactcctc cccactgaca tagagaactg tccccacttg ggacaactgg
     8521 gttgagactt gtaggagaag agttgatttc ccaatcccag gatccccacc gatgaggacg
     8581 agacttcctg gtaccactcc gcctccaagc acacggttga attcctccat ctccgtctta
     8641 gttcgattga cattgatgga agtcacctca gctagtttca tgggcttggt tttctcacct
     8701 gtcaaggaca cacgcgcatt cttgacctcg gcaacctcaa cctcttccac aaaagaagac
     8761 caagacccac agttggggca acgtcccaga tatttagggg aattataccc acaattttga
     8821 catacaaatg tcgctttttt ctttgcgatg acaaacctct ttctatatct ctaactcaca
     8881 ctcaatcact tggcaaaaat caatcttctc atttggcaca aactggcgca tgagcattcg
     8941 atgagcaaca actaccacag tctgatgttc tcgatactta gacatacatt ctagaaaccg
     9001 agacttcatt tccgtagctg tctcatattg aataggacta ttaggaagca tctccccctt
     9061 gttttctaaa aacagtcttc tagctgtttc aaagttttct attcctgttt tatagacctg
     9121 ccattcatgt aataaaggct ctactcttaa aggaagaccc gtagcacaga ccacatacga
     9181 agccgtttct aaagctcttg tgactgcaga agatacgatt atttcagctg acgagagtaa
     9241 aggatttttg ctcaatttct ggacttgctg ccgtcccatc tcagacaagg gtgccaaatc
     9301 tatcccaaat cctatataag aacgctcctc taactcacgg taatctggct ccccatgacg
     9361 tacaaagata atcttcattc tagtgccctg tcgatccaaa tccaccagtt cgaacgccac
     9421 cagctgcatc tccatctgca attaagaaag tagcaaaaac agcctggaca atacgttccc
     9481 caacttcaag aacaacctct tggtctgtga tattcttcat ctgcgcaaaa atatgccctt
     9541 catttccagg atttccataa taatccccat caatgacccc aactgagtta attaaaacca
     9601 agcccttctt acgaggattt gaagaacgat catagaggta gagaacctca gtcggctgca
     9661 tataagcctt aacccctgtc ggaaccaaga caatctctcc tggcgcaaca actgtacgca
     9721 cagcaacctt taagtcgtaa ccagccgcat gcgctgtctc acgcttgggc aataaatttt
     9781 catctgtaaa actcgaaacc aattcaaaac cacgaatttt cataattttc tcttttctat
     9841 tatcatttat tctagattat tctatcttat ttattcggaa aaagcacgaa aaaaagagca
     9901 cacaattcaa atcgcttagg gctgctggat tcctcccctg acccgcttca cgcagaactg
     9961 ttgctccact atttattata tcacattcct attcatttta aaagcaaaat tattttttcc
    10021 gtctatttct aaaaaaatcc tgcatgatag ctgcgcattc atcttccaaa attcctattt
    10081 caacctccac acgatgattg agacgctcat ctgtcaagat attgtacaaa ctcccagcag
    10141 cgccaaattt ctggttttta gccccataga ccacatttgg aatgcgggca agcccaatcg
    10201 ctccactaca catgacacaa ggttcaatgg tcacaaaaag tgtgcaatcc agcaagcgcc
    10261 agctctcctc actcaagttc gcatcctcta tagccataat ttccgcatgc ataaccgctc
    10321 gctgtaattc ctcacgcgca ttatgcccac gaccaatgat ttccccatct ttgacaatca
    10381 cacaaccaat tggaatttca tcgtgttcaa gagcaatctc agcctctctc aaagcctccc
    10441 tcataaagac ttctttttct tcaagcgtat aatacatctc ttttctcttt tcctacttat
    10501 cgattttatt attatatcat gaatcccaac acaaaaaaag ccaccgaatg cggtgactct
    10561 atagggagat tattatgaaa aagaaaagtt taggatattt gttacaacaa gttaggaggt
    10621 cttcttgtaa ccgtctatag tatacccgac ctatcttaaa caaatcttaa aaatctctta
    10681 ggaccaaaca ctttctaaaa tatttgtttg ttcacgacca ggacctactg agaaagtaga
    10741 aatacgaacg ccaaccaatt cactcacacg acgaacatag ttacgcgcat tctcaggaag
    10801 atcttccaaa ttgcgaactc cggtaatatc ttctgaccaa cctggcaact cttcatagat
    10861 aggcttgcaa cgtttcaatt gttcaagact agctggatag tagtcaatac gttgaccgtc
    10921 aagatcatag gccacacaga ttttcacagt atccaaaccg ctcaaaacat caatagagtt
    10981 caaagaaagg ttagtaatac cagaaacacg acggctatga cgcatcacaa ctgagtcaaa
    11041 ccaacctaca cgacgtggac gaccagttgt tgtaccatat tcatgaccca cttcacggat
    11101 acgttctccc acttcatcaa acaactcagt tgggaaagga ccatctccta cacgactcgt
    11161 ataagcttta catacaccta caaccttgtc aatcttgctt ggaccgacac cagaaccaat
    11221 tgtcacacca ccagctacag ggtttgatga cgtaacaaat ggataagtac cttggtcgat
    11281 atctagcata acaccttgtg caccttcaaa aagcacacgt ttgccattat caagcgcatc
    11341 attcaagata acagatgtat ctatcacgta tttcttgatt tgttgaccat attcgtaata
    11401 ttcttcaaaa atatcatcga aaacaatcgc tttactgtca tacaattttt caaaaagacg
    11461 attcttttca gcaaggttac gttctaaacg ctcacggaaa atatctttat ctaaaagatc
    11521 tgcaatacga attccaacac gagcagcctt gtccatataa gctggaccaa ttcccttaat
    11581 tgtcgtacca atcttattgt cgcccttagc ttcttcttgc aagcgatcca actcgatatg
    11641 ataaggcaaa ataacatgcg cacgatcaga aatacgcaag ttatcagttg ttacaccttc
    11701 ctcatgaaga taactcaact cttttacaag agatttagga tttacaacca taccattccc
    11761 aatgacagat attttttcag ggaagaaaat cccagatgga atcaagtgca acttaaattt
    11821 cttaccgtca atcacaatcg tgtgaccagc attatcacca ccttggtaac gtgcaatcac
    11881 ttctgcattc gctgaaagga agtctgtaat cttcccttta ccttcatcac cccattgggt
    11941 acctacaaca acaactgaag tcataatttt gtctgagcca tcaggctctt cctttctcac
    12001 atacatggca ggactctcac ctgcaattat atcttacaat ttattataat aaaaaatcgc
    12061 ctttttatca agaagaaaca atagaaagat ttgctatttc caactattaa aaaatgattt
    12121 agaaaaatta ctagctattt actatcatct ttccataaaa gagtaaatta gttcggaaat
    12181 ttactaaaat tacctcaaca agaaataaaa ccccgattca ttaccaattt ttcaagatac
    12241 aaacgataag caacacgata atggtaaacg ataaaatccc tacgacaacc aatgccatat
    12301 ctcactaaat aataaattaa aaatttaaaa tgaacatgtt cccagtcaaa attatcacca
    12361 aatgtaggac catactcttc ttcaatacta tcatagaaat tagccatctg ctcataaatt
    12421 ttttgtaaca taatcaaata ctccttttct tttttataaa cttattctaa caaaaaattt
    12481 tacacattca ctatcaattc ctgaattgtt aaaataccag cctcaacaag ataaaaatag
    12541 gaaaagttga caaaatagaa acaaatttgc tacctaaatt tcaaacaatt aaagttctaa
    12601 aaagaccgcc ttaaaacttt tgggtaaatc ctattagaac tataatattt ttatataggt
    12661 attatggttc tgattttcta gtataaaaaa attcaaacta gaattcttct tagaaaaggc
    12721 cgttttaagt gctatcattg ctcaaaaatg gagctcgctg agacttctat cgtcaagaag
    12781 aatcatcaaa ttccttgtat catcaaccaa aagattgctc agaagctaat taaaaagact
    12841 tctatgaccg acattgatca tcagttgtct atttcaactt caactgtcat tcgcaagatc
    12901 aatgattttc actttgagca tgatttttcg cgtcttcctg agattatgtc ctaggacgtt
    12961 gaaacagtcc ggggagtgac tgtttcaatc gggagatgga gatgagcttt attgctcaag
    13021 actttgataa gctcaatatc ataactgttc ttgagagcag aacacaagcc atcatccgaa
    13081 atcccatgaa tacaaggcta tcaagcgata ctgaaagctc attcaacaag atagtcagaa
    13141 actgagtgat aaacgatttt atcgccctac ttttcgtatg cacttgacta ataaagaaat
    13201 tctagataaa cttttgagct attccgaaga cttgaaacac cactataatc tctatcagct
    13261 cttgcttttc ctcctctttt tcagactctg tttaaaacct tcctcaaaga taaagagaaa
    13321 atcgtcaacg cccttcaatt accttattcc aacgccaaac tggaagccac caataatctc
    13381 atcaaactta tcaagtacaa tgcctttggt tttaggaact ttgaaaactt caaaaaagaa
    13441 aggacgaaat ttgtcctttc tagatcttcg ctttcttcaa cccactacag ttgacaaaga
    13501 accgaaaaat gtctcgcctc taatatagtc aattgaaaca agaacaagac aaaagagcct
    13561 cataaaaggt attgcaactt ggtaatacct ttttggggtt ctttttgata tgaacccatg
    13621 ttttctcaat aggattgtac tcaggtgagt agggaggaag aggtaaaagt ttatgcccaa
    13681 actcttcaca caagagttct agcttaccca ttctatggaa tcttgcattg tccataatat
    13741 agtagattga aactagaata gtacacctct acttctaaaa cattgttaga attcgatttt
    13801 actgtcctga tcgatttgtc ctattcttat ttcattttac tataacacga aatagattat
    13861 tattacataa caaaaaagag gtctaaacct cttaactaaa ttactccgcc agtaggactc
    13921 gaacctacga catcatgatt aacagtcatg cgctactacc aactgagcta tggcgga
//
LOCUS       DAVLZS010000045        13525 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLZS010000045 DAVLZS010000000
VERSION     DAVLZS010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.045"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            323..1669
                     /gene="gdhA"
                     /locus_tag="VYO88_001585"
     CDS             323..1669
                     /gene="gdhA"
                     /locus_tag="VYO88_001585"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1719656.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2165..2335)
                     /locus_tag="VYO88_001586"
     CDS             complement(2165..2335)
                     /locus_tag="VYO88_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719657.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2348..2926)
                     /locus_tag="VYO88_001587"
                     /pseudo
     CDS             complement(2348..2926)
                     /locus_tag="VYO88_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(2943..3747)
                     /locus_tag="VYO88_001588"
                     /pseudo
     CDS             complement(2943..3747)
                     /locus_tag="VYO88_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            4198..4892
                     /locus_tag="VYO88_001589"
                     /pseudo
     CDS             4198..4892
                     /locus_tag="VYO88_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(4937..5386)
                     /locus_tag="VYO88_001590"
     CDS             complement(4937..5386)
                     /locus_tag="VYO88_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1719658.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPINIKKVVFKVKI"
     gene            complement(5891..6346)
                     /locus_tag="VYO88_001591"
     CDS             complement(5891..6346)
                     /locus_tag="VYO88_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HEV1719659.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            complement(6368..7828)
                     /locus_tag="VYO88_001592"
     CDS             complement(6368..7828)
                     /locus_tag="VYO88_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1719660.1"
                     /translation="MYDVVVIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIEKGGTVFSSMEELMNVSDFYQITIPYQPE
                     VYESVLTEMLNESNVDILLNVEINNIVFDNNKIHSVEIISNQEVNYLESKVFIDATGN
                     ATIASASGANVYEKNSSYGCLMRVGGVDITKTLEHIEKTKQWEFEEGYNEWLDNVLAN
                     RKYRATGAVLRDPVSYDHAPMLTKDDHFMNEEKWSYIKERWERFGFIYTLEVSLFRNE
                     LREAVEAGDFEFEIYHDDESGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            complement(7891..9468)
                     /locus_tag="VYO88_001593"
     CDS             complement(7891..9468)
                     /locus_tag="VYO88_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1719661.1"
                     /translation="MVKLNKVLKGSVALLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDQTLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSKHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            complement(9537..10976)
                     /locus_tag="VYO88_001594"
     CDS             complement(9537..10976)
                     /locus_tag="VYO88_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719662.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYVKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            complement(10990..11919)
                     /locus_tag="VYO88_001595"
     CDS             complement(10990..11919)
                     /locus_tag="VYO88_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1719663.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            complement(11930..12862)
                     /locus_tag="VYO88_001596"
     CDS             complement(11930..12862)
                     /locus_tag="VYO88_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1719664.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            complement(12863..13510)
                     /locus_tag="VYO88_001597"
     CDS             complement(12863..13510)
                     /locus_tag="VYO88_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1719665.1"
                     /translation="MVSCQALEGEPLYTPNGGVMPLLAKAAFQAGAKGIRANSVRDIS
                     EIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILALDCTNRSRPGYDNI
                     TDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYTPYSPKKDNPDFEL
                     VERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPLEIAKKFIEVV"
BASE COUNT         4403 a         2551 c         2004 g         4567 t
ORIGIN      
        1 tttttgattt tagtctggta taaatattgc tttcctccaa aatggtcata attttactag
       61 caaatctaac atatcacgga taaattaaca agtgatttct gaattgctaa acattttctt
      121 ttcttatagc ataccatact ttaagatttt gtctttgaga aagatatttc caagaaaaac
      181 gttcgttttt ttatctattt tcaaaaaaac caaaaactga attgaaagaa tttttagaaa
      241 atttctgttt tttctttaca gtgaaaaaaa attctgctat aatgtcttat gtaataaaat
      301 atgacaataa aaggagaacg atatgacatc tgctaaagaa tatatccaaa gcgtgtttga
      361 aactgtgaaa gctcgtaacg ggcacgaggc tgaattcctc caagctgttg aagaattttt
      421 caacactttg gaacctgtat ttgaaaaaca ccctgagtat atcgaagaaa atatcttggc
      481 acgtattact gagcctgagc gcgtggtttc tttccgtgtt ccttgggttg accgtgatgg
      541 aaaaattcaa gtaaaccgtg gttaccgtgt tcaattcaac tcagctgttg gaccatacaa
      601 aggtggactt cgtttccacc caactgtaaa ccaagggatc ttgaaattcc tcggatttga
      661 acaaatcttt aaaaatgtct tgactggact tcctatcggt ggaggtaaag gtggatcaga
      721 cttcgatcct aaaggtaaaa cagatgctga agtgatgcgc ttctgccaaa gcttcatgac
      781 tgaattgcaa aaacacatcg gaccatcact tgacgtacct gctggtgata ttggtgttgg
      841 tggacgtgaa attggttacc tttacggtca atacaaacgt cttaaccaat ttgatgctgg
      901 tgtcttgact ggtaaacctc ttggatttgg tggtagcttg attcgtccag aagcaactgg
      961 ttacggtttg gtttactata ctgaagaaat gctcaaagct aacggtaaca gctttgctgg
     1021 taagaaagtc gttatttcag gttctggtaa cgttgctcaa tatgctcttc aaaaagcaac
     1081 tgaactcggt gcaactgtta tttctgtttc tgactcaaat ggttatgtca tcgatgaaaa
     1141 tggtatcgac ttcgatcttt tggttgatgt taaagaaaaa cgtcgtgctc gtttgactga
     1201 gtatgcagct gagaaagcaa ctgctactta tcatgaaggt tctgtatgga cttacgctgg
     1261 aaactatgac attgcgcttc catgtgctac tcaaaacgaa atcaacggtg aagcagctaa
     1321 acgtttggtt gctcaaggcg ttatctgtgt atctgaaggt gccaacatgc caagcaacct
     1381 tgatgccatc aaagtttaca aagaaaatgg tatcttctac ggacctgcca aagctgccaa
     1441 cgctggtggt gtagccgttt cagcccttga aatgagccaa aacagccttc gcctctcatg
     1501 gactcgtgaa gaagttgatg gccgtctcaa agacatcatg acaaacatct tcaacacagc
     1561 taaaacgact tcagaaacat acggtcttga taaagactac cttgcaggag ctaacattgc
     1621 tgcctttgaa aatgtagcaa acgctatgat tgcccaaggt attgtttaag atttatttgc
     1681 ttaatcctca atcactacga ttggggattt ttagttgagt tagacagttg ggaaattcta
     1741 attaaatgaa ataaaaactg aacaaattga ttgcggaatt caaaccaatt tctaacatac
     1801 ttctagaaat taatttgact tttctaatcg atttgttcat atcttatttc aatttactat
     1861 acttacttaa ccctttttat actcaatgaa aatcaaagag caaactagga agcgagccgc
     1921 aggctgtact tgagtacggc aaggcaaagc tgacgtggtt tgaagagatt ttcaaagagt
     1981 attaaacaaa aagaaaaacc gctactccta agaatagcga tttaatcatg tttttaagct
     2041 actactgtag ttgctctatt atttaagtgt tatgaataac ttcaatatct ttaaagcttt
     2101 ttgttagatt tataatttca actatagcca tctctactcc ttagtttaca gcaaaaaatt
     2161 atgcttaatt cttattgttt ttgtaaacaa tcagcgaacc caatactatt ccattcaaca
     2221 agcctaaaga aataccatat tcaactggaa aatctaaaaa aattgcaaac actattccaa
     2281 tcatcacccc tagtgaggct attgttaaaa ttacatattc attttctttc ttcattttct
     2341 ttacacctca tttccttttt gtatataagc tgtagtactc tccaccaaga gtcattaagt
     2401 acttatgatt tcctgactca acaatcttac cacctttcat tacaaaaata atatccgcat
     2461 ccttaatcgt tgacaatcta tgagctataa ttatttgagt acaaccctga ctttgtatat
     2521 actttgttat tctttcctca ttaatagtgt ctaatgcact agttgcttca tctaaaatta
     2581 caatactagg attatttatt aatgcacgtg ccagtgctat ccgttgcctt tgcccacctg
     2641 aaatatttga ccccatctct gagatgatag tattaaattt catcggcata gccatgattt
     2701 catcatagat ttgaactgct ttacaaactt cctctatctt ttgtgaagta acttcgtgct
     2761 ttaaagttat attatcaaga atacttctgt tcaataaaaa cgaatcctgt ggaactactc
     2821 ctaaattttg acttaatatt tttttatcta tttgattaat atttacacca tcaaataaaa
     2881 cttttcctgt atcaatctta tataatcttg atggtatttt tgataataga cttcctgcaa
     2941 aactagaatc ctagttcatg attgataatg ccagcaatca aattcattcg taatccgaag
     3001 cgtttacgat gatttcgata ggttgttgaa aacattttaa acgtttctac tttggcaaag
     3061 atgttctcaa ccttgctttt ctccttggat agcgcatggt tataagcttt atcttcaact
     3121 gttagcggct tgagtttgct ggatttacgt ggagtttgtg cttgaggata tatcttcatg
     3181 agcccttgat aaccactgtc agccaagatt ttaccagctt gtccgatatt tctgcgactc
     3241 attttgaaca acttcatatc atgacaatag ttcacagcga tatccaaaga aacaattctc
     3301 ccttgacttg tgacaatcgc ttgagccttc atagcgtggc atttcttttt accagaataa
     3361 ttcgctaatt gtttttttag ggcgattgat ttttacttcc gtcgcatcaa tcattaccgt
     3421 gtcctcagaa ctgagaggag ttcttgaaat cgtaaaacca ctttgaacaa gagttacttc
     3481 aacccattag ctccgacgga ttaagttgct ttcgtgaata ccaaaatcag ccgcaatttg
     3541 ttcataagtg cggtattctc gcacatattg aagagtggcc ataagaaagt cttctaggct
     3601 taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt ttaatacagc
     3661 taacatctct tcaaaagtcg tgcgttgaac accaacaaga cgcttaaatc gtgcatcggt
     3721 tagttgttta cttgcttcat aattcataga actattatac catattttgt ttcgcaggaa
     3781 gtctattgaa aaatctccag actagagaac tcacggatag ttcctaatct ggagatttct
     3841 tatttgcact tttcttgtac aactttagtc catggtaaat aggcctctaa aacctctttg
     3901 tttacgagag tttcctcgtt tggaagacat tctagaagat aggatagata tttctcgcta
     3961 tttatactag actaaaatca aaaagcatta tataatagtg atatgaaatc aactaaagaa
     4021 gaaatccaaa ccatcaaaac acttttaaaa gactctcgta cagctaaata ttataaacgc
     4081 cttcaaatca ttctatagta aaatgaaaca agaacaggac aaatcgatca ggacagtcaa
     4141 atcgatttct aacaatgttt tagaagtggg ggtgtactat tctagtttca atctactata
     4201 tttcgtctga tgggcaaatc ttataaagag attatagagc ttttagactg taatcaaaca
     4261 acgatttagc gaaatgtaaa aaaatatgag gagttcggac tcgactctct ccttcaagaa
     4321 acacgtagtg gtcgtaacca tgcatatatg acagttgagg aagagaaagc ctttcttgcc
     4381 cgtcatttga aggctgcaga gtcaggagaa tttgttacaa ttgatgcctt atttcaggct
     4441 tataaaaagg agttaggtcg ttcctacaca cgtgatgcct tctatcaact gttgaagcgc
     4501 catggctggc gaaatattat gccacgtcca gaacatccta agaaagcaga cgctcaaacc
     4561 attgtcgcgt ctaaaaataa aatctcaatt caagaagaca agaaagcgct ttaaaatcag
     4621 tagacgtttt cgtaaggttc gcttgatgta ccaagatgag gctggtttca gtagaatcag
     4681 taaactggga tcttgttggg ctccaatagg agtaggtcca catgtccata gtcactatat
     4741 acgagaattt cgctattgtt atggagctgt tgatgcccat attggaagat gtcataaatc
     4801 aacttcaaga tgtcatacaa ggactggaga aggaggtgat aaagtccatc gttaatcgga
     4861 gatggactag aatgcttttt gaaaacagat gagtattaaa tattttaaaa ttcttaatcc
     4921 ctgaaagtac tttcagttaa atttttacct taaaaacaac tttcttaata ttaattggtt
     4981 cttcaaccaa taggcctgtt ttatgtgcat cgtttggttc caacaaaagt aacatatctt
     5041 tctttaattt aatactaaat aaagctgtcc cattcatttg ttgccaatca tcatctactt
     5101 tatattcaga caattccatt tgagacaaga aattatataa aattatttct tctccattta
     5161 acagataatg gacatcataa tattccttat gactttccca cggtctattt tcttcagttg
     5221 tagtttccat atcaattata ttgtaaaaga aatcagtaga aattttatgt atgccacctt
     5281 tatcttttgg tatatcatga ttatttagaa actcttttac tttcgttatt gcgatatgct
     5341 catgaaccgt attaacatgt ccatttttaa attcaactaa ttccatagtt ccctcctgtt
     5401 ataaattttc ttgattaaaa ctaactggta gtagttcttt aagtttatat actttataag
     5461 tatcaacatc actagccaat ataactacaa atgaatcaag attacaaaat tctatcatta
     5521 cctgacaaga caccctgcaa gatgctataa aagatgataa aatacctttt tttccgccta
     5581 caatacatat ttttgaaaac gaacgttctc ctttaaatac agctttgtaa aaatatactc
     5641 gttctgcaca gcaagtagga gaaaagcaac attttctata ttacatccag aaaaaaattt
     5701 ttatcttcag tttctaacgc agctccaacc ttaaaataag aataaggagc ataagcttgg
     5761 accattgatt taataacctc tgatataatt actttataag tcattcctaa aatatatttt
     5821 tcgaaaaatt atatcatcca caacctagtt gtaatataca aggtattaaa tctaatcgaa
     5881 aatgtggagt tcagtttgaa tcatctaata attgttgata ctctctataa tgtctatcaa
     5941 tagcagacct cagtttttta ataattggtc catgcttttc tatagtaaat tcaaactcag
     6001 gattgctaaa aactgaagaa tcatatctat gaactacagt ttttcttctc tcttcctctt
     6061 cccacatgta tctcggaaat aaatgagcat gaagtacagg tgttgaattt cctaagatat
     6121 cataattaat tctataggca tttaacactt caagcatcgc atcacctaat atactcattt
     6181 ccattaaaaa ttcttttcta aattccattg gcatatcaga taaagaagga tagggttctt
     6241 ttgaaaaaag aatacaatat ccttcaaaaa actgagaata agacatttct acaaagctag
     6301 tatcaaattc ataaacaaag tattgatttt tattagtatc attcatttaa tattccctta
     6361 ttatttgtta atcagtaatc caattagaaa actcccatgt aaataatata tctaagttcg
     6421 atttaaacaa atctctatta atgtttagag tattgctttt atcttcaata atagtttttg
     6481 ccgctgctgc tgatgatatc cccattaaca tacaactaat ttgtgatcta aaactttcgg
     6541 attggtaagc acctttacct attacaaaca aattattcaa ttttccacct acaattgatt
     6601 tatacgttat ttctttagga gtttgatagc tatacatagt cttaaatgta tacattggaa
     6661 aatcaagaat ttcgtccatc atagatgaat tatcaatgtg cctacatgat ctgttagtag
     6721 ctctagttcc ctgatcaagg ataaaagaat tttcaaaacc tggtacatat tttttaagaa
     6781 aagataaaaa tgttaaatta tattttctag aaagaatatt agcatgtgat tcatcttcca
     6841 tatatttggg attgaatcca aatgcttttg caacattaat taatgctaca ttttgacccc
     6901 atgaaccata actgatacca tcaccgttca tagttactcc agattcatca tcatgataaa
     6961 tttcaaactc aaaatcacca gcttcaactg cttctcttaa ttcatttcta aacaatgata
     7021 cttctaaagt atatataaac ccgaatctct cccacctttc cttgatataa ctccattttt
     7081 cttcattcat aaaatggtca tctttagtta acataggagc atgatcataa gaaacgggat
     7141 ctctcaatac tgcgcctgta gctctatact ttcggttagc caatacatta tctagccatt
     7201 cattataacc ttcttcgaat tcccactgct tcgttttttc aatatgttca agagtcttag
     7261 tgatgtcaac tccacccact ctcattaaac agccataaga agaatttttt tcatatacat
     7321 tagcgccact tgctgaagct atcgtagcat tacctgtagc atcaataaaa acttttgatt
     7381 caagataatt tacttcttga ttactgatga tttctacact atgtatctta ttgttgtcaa
     7441 aaactatatt gttaatttct acattcagaa gaatatcaac attagattca tttaacattt
     7501 ctgttagaac tgattcatag acttcaggtt ggtacgggat tgtgatttga taaaagtcgc
     7561 ttacattcat caattcttcc atcgaagaaa aaacagttcc acctttttct ataatacgtt
     7621 caattaactc accaacaatc ttactggcat ttactctccc agaatcatcg aagtaaagat
     7681 ttgcaaatga acccattaga gtattaatcg gtacgccacc tatacgactc cctttttcga
     7741 ttaaacaggt ttttaatcct aggcgaccag aagcaattgc tgcaagagca cctgaactac
     7801 cagcacctat aactacaaca tcatacattt tcgaatattc actttctagg cttagtagct
     7861 ccctgaataa tcagagagct accatttaat ctatttcatt ctatctttga cacgtttgta
     7921 ggcatcatta tatacttttg taactttatc caagtcttta gatttagctt cattgataaa
     7981 tgaatcccac tcactcatat ctctttgtcc ttcaatgaat ttaataatat tttcatcaaa
     8041 gaaagtattt aatcctgctt cagatttagt taaaacatct aattcttcag ttgtaaagga
     8101 aagaaccgga gtatctggtc taaaaccacc taaatctttc ttaattttat ctacttgatc
     8161 atacataact ttagggaatg ttcctggctg tgcctcaata tctaatttag tttgaacgcg
     8221 agtaaatgct tggttaccat gtttaaacag cagttctgct ttatcatttc cagcattttc
     8281 accgtaaatt tgaatcaacc atttaatacc tgcttgagta ttagggtttt cacgtgtaaa
     8341 tgttttacct tcaaatccaa tagcaagttt ttcttgattt tcatcagcgt ataagaaatt
     8401 aaagaattct aacgctttat caatttcttc ttttggtgca ttggcattga ttacccaacc
     8461 tgaatcagaa atgtacggtg ttttcggttg caaataacgt tttccattaa tttctggata
     8521 aacaagtggc tgccaatcaa atgatttatc aaagttatta tctccaatga tattcatacg
     8581 gtcaacagtg aatgaaccct tgttagaagc caatagacct tcccaagttt catctttcat
     8641 aactgcccag tcagggtgaa gtacgttatc tttacgtaat tctttcaacc attcaacgaa
     8701 ttgtttcaat tgaggttgtt caactggatg tttatatgaa tctgattcat agtcatagta
     8761 tgtacgatgg cttaaattcc acaatggtgt aactcgcttc atgaagcctt catagccatt
     8821 acgttgaata aatgctggag aaccttgttt ttcagtcaaa tatttcaaaa cttttgtata
     8881 gtcatcaaca gttttaattt ttgaaagatc ttcaaattct gaaccaacaa gtaagtcttt
     8941 tctcagaatt ggtgtagtat acatgatatt ctcatcagta aagaattttg tgaaagcata
     9001 aatatgtttt tcatcatctt ctatttgagc taatgcatta tttttttcaa ggtacttctt
     9061 atagtttggt agtttgtcca tgtgttttga caaatctaag aatgcaccct gtttaccaag
     9121 tttgttgata ccagcgatat cactcttatc tcctgttgtc aacaaaacag tcggtaactg
     9181 gttactagta ataagagaat ttactttaga acttactccc tcgccaggaa tagttacaag
     9241 atcaatatca atacctagct gttcttctaa ccactgacca acaagtgttt gatctttagg
     9301 tggacgaaca tcattaattt gccatgtaga tagaaacgaa attttcgttt taccatcagc
     9361 tgttttttca gcaggctttg aattagcgtt attgccacaa gctgctagca ataaacttgc
     9421 actcaggagt gctacactcc cttttaatac cttattaagc tttaccataa taagacctcc
     9481 attttatata tctatctcca ctaatataga gattatttgt taacgaatta atctggttag
     9541 tatttgagat agtgttgctg aatactacct tcaataccat acaattttgc attctcgatt
     9601 tcaaatttga acgcaactgg agaattacct aaatctaaga tagatttttt attaaattcc
     9661 aacttatact ttccatcgga aacttgaaca agagagatat cttcctgacc aaaatctgaa
     9721 taagcattac cgtatttagt acctaccgca actttaacat aaccattttc aggaatatca
     9781 gctaagatat aaatttcatc atcgtaagtt tggaagctaa ctgtagatat tttagctgga
     9841 attccttctc ttttattagt ataataagca aattggtctt tcttaatata tcctctagct
     9901 aatgaacttt ctcggaagcc agtgtgatta ccatttccac ccatatagta gaaccaaatc
     9961 ttatcatctt caattattgg agcagccgtg aaaatacaac tagcatcaaa atcagcattc
    10021 tgcgggtata ctccacctcc cctttcaatg agatagtcgc ccttacatac actatcccat
    10081 tgttccaaat tagcagagaa tttcaattct aagtctactt tatcatagtt ttcatttaaa
    10141 gtgtcgcctt cgtggtacat tgaagcaaaa cctaaataga tatccgcgta tgaaattact
    10201 ggcatagaat aaatttgatc ttcaaatcca tctcccctaa ggatttcttt aggttctgac
    10261 caattaataa aatcatcact gaaagtaatt gcacttagac gtacgttatt tgcccaggtt
    10321 cttgtaataa cagcgtattt accagttttt ggatctctaa atggaaaatt atgactatct
    10381 gctgcaggat tccatttttt ccatggaata ggttcgtcaa aatgaatacc gtcttctgaa
    10441 aaaacaacaa ccatgtaatg aagattcgga gaaaattcta attttgaaac taatttatat
    10501 cgtttcttag gatccaactc ctgttcatct agcatgatac ctgcaccgtg tgcatgcatc
    10561 agaacaatat tattatcttt tgaaccttta aattttacta gattgagatt tggtttttcc
    10621 cattttactc catctttact ttcagcatag caaagtgctg tcattctaga tgacttgaca
    10681 atgtattcct tctctccacg ttctgctaaa ggagtctctt cgcttgcttc atcactaaca
    10741 aatgtttgat accaacatct atataatttc aattctttat catagataac gtttggatat
    10801 gaattatcaa aacgaacttc ccataattta ggattttcgg caaaatactc ttcaccaaat
    10861 agtggattgt tttcagtatc tttttttagc ttatttaatt ttaattgagc attttctaat
    10921 gtatacccaa ctactaaacc gctatctaat aaaagatatt tttttaaatt ttgcaaaata
    10981 attaccttat taacctttca cagaacctag caggattccc ttaacaaaat gtttctgaat
    11041 aaatggataa atcatcataa ttggaataac actaacaaca atagtaccca tcttaatagc
    11101 aatacgcata ccaatacctc caccttgagc agcaatttgt tggtaatatg tattacctgc
    11161 agaaagtgat aattcagcag tatcagttgt atttgtaaca actaaatttc tcaaataaat
    11221 agataaaggc atcttagtgt cgtcattcaa ataaagtaat ggaggagtaa aactattcca
    11281 tgaaccaact atgcaataaa gtgctataat catgaaaata acttttgata atggtaatac
    11341 taaattccaa aaaattctaa attcacttgc cccatcaatt ctagcagact cacgaagctc
    11401 cattgggatt gatttaaact gtgttctaaa caaaattata taatatgtag aaacagcacc
    11461 aggtaaaaca agagcccaag cagtattcaa taaaccgagg tttgcaactt gtatataaag
    11521 cgggatcatt cctccactaa agaacattgg aatcaaaata agagtattcc agaatttttt
    11581 acccctaatt tcaggaattg taagtggata ggcatacata ctacataccg caacactaac
    11641 aattgtagat agtgcagcat acaatacact attaccatat gcttgccata gtttagaatc
    11701 cccaaaaata aacttatatg cagtaatatc tatttttaag ggaaataatt taacaacgtt
    11761 tttagatagc caaactggtt ctgaaagtga cgtcatcact acccaccata atggatacaa
    11821 cataagtaag gttattatta ttaaaatgaa tataaagaga taatcaacga aggtttcttt
    11881 gtctctatta ctcttttttg tattttttga aaaaatcatt ttacccccct tatacaattc
    11941 cttcttcgcc aagtttttta gcaatcttat tagctaataa aacaaataac aaagctacta
    12001 tgttattaaa taatcctact gcagctgagt aactgaaatc agaatttaaa ataccttgtc
    12061 tataaacata agtagataat acatcagata cttcatatgt tgcaggacta gacatcaaga
    12121 ataccttttc aaatcctact tgcatgatac caccagcatt tagtataaac aaagtaacta
    12181 ctgtaggtct taaacttggt agagttacat gccacatttt gtgccatcta ttagccccgt
    12241 ccatatctgc tgcttcatat aaagttgaat ctatattggt taatgctccc atataaatga
    12301 tagaacccca acctattgtt ttccatactc ctgaaccaat gtagagaggc aagaaccatt
    12361 cagattttgt aaagaaactt attggctcca ttccaagtga tgaaagtaaa ctgttaataa
    12421 taccatatga accaaatagt tcaaaaataa taccaaccat aaccactagg ggaataaaat
    12481 gaggaagata actaatagat tgaactacac tcttaaatct tacttttctg acttcgttta
    12541 atatgagtgc aaaaataagc ggagctggga aagagaataa aaagtctaaa acccctacca
    12601 tgaacgtatt cttgaacaat ctataaaaca aaggatctga gaacaatctt tgaaaatgtt
    12661 ttaaaccgac aaatggactt ccagtatatc ccttgaagac agtaaagtct tgaaaggcca
    12721 taataatgcc gtacattggt ccatacgtaa ataaaattag tagaacagtt gctggaatca
    12781 tcattaaata taaaatccaa tatttttgaa tatgttcaac tgtcaattga atcttactct
    12841 tttttaatat ttcttgattc atctaaacta cctcaataaa cttcttcgct atttccaaag
    12901 gacgagtgat agctcctcca acaaccactg cgtaagcacc taaatctaac atttttctag
    12961 cttgttccgg agtacttatt cttccttcag caataactgg tacgtcaagc tcttttacca
    13021 atctttcaac taactcaaaa tcaggattat cttttttagg gctatatggt gtataaccag
    13081 ataatgtcgt acccacaaaa tctactcccg attcagcagc tactttccct tcttcaaaag
    13141 tagaaatatc agccattaat aattggtttg gatacttgac tttaatatca tgaataaagt
    13201 cagtaatatt atcataacct ggtcttgaac gattagtaca atccaaagct aaaatgtcta
    13261 ctccttcact aactaattca tcaatctctt tcatagttgc tgaaataaaa ggttcaaagc
    13321 catcgtaatc tctttttatg atacctataa ttggtaagtc aacttcttct tttatttctg
    13381 aaatatcgcg gacagaatta gcacgaatac ctttagcgcc tgcttgaaag gcggcttttg
    13441 ctaataacgg catcactcct ccatttggag tataaagtgg ctctccttct aacgcttggc
    13501 aggaaacaat tatttgacct tttaa
//
LOCUS       DAVLZS010000046        13493 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLZS010000046 DAVLZS010000000
VERSION     DAVLZS010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13493
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.046"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(283..1890)
                     /locus_tag="VYO88_001598"
     CDS             complement(283..1890)
                     /locus_tag="VYO88_001598"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1719666.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2280..2867)
                     /locus_tag="VYO88_001599"
     CDS             complement(2280..2867)
                     /locus_tag="VYO88_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1719667.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(2995..3444)
                     /locus_tag="VYO88_001600"
     CDS             complement(2995..3444)
                     /locus_tag="VYO88_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719668.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3449..3838)
                     /locus_tag="VYO88_001601"
     CDS             complement(3449..3838)
                     /locus_tag="VYO88_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV1719669.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3866..4492)
                     /locus_tag="VYO88_001602"
     CDS             complement(3866..4492)
                     /locus_tag="VYO88_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1719670.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVFASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4506..5069)
                     /locus_tag="VYO88_001603"
     CDS             complement(4506..5069)
                     /locus_tag="VYO88_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1719671.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5234..5468)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5522..6025)
                     /locus_tag="VYO88_001604"
     CDS             complement(5522..6025)
                     /locus_tag="VYO88_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1719672.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLSEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6218..7048)
                     /locus_tag="VYO88_001605"
     CDS             complement(6218..7048)
                     /locus_tag="VYO88_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1719673.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7033..8715)
                     /locus_tag="VYO88_001606"
     CDS             complement(7033..8715)
                     /locus_tag="VYO88_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719674.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKKEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8826..9074)
                     /locus_tag="VYO88_001607"
     CDS             complement(8826..9074)
                     /locus_tag="VYO88_001607"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719675.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            complement(9081..9629)
                     /locus_tag="VYO88_001608"
     CDS             complement(9081..9629)
                     /locus_tag="VYO88_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1719676.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9644..10492)
                     /locus_tag="VYO88_001609"
     CDS             complement(9644..10492)
                     /locus_tag="VYO88_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1719677.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10680..12029
                     /gene="trkA"
                     /locus_tag="VYO88_001610"
     CDS             10680..12029
                     /gene="trkA"
                     /locus_tag="VYO88_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1719678.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKEVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            12033..13472
                     /locus_tag="VYO88_001611"
     CDS             12033..13472
                     /locus_tag="VYO88_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1719679.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLITLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
BASE COUNT         3941 a         3070 c         2526 g         3956 t
ORIGIN      
        1 aatttgactt ttctgataga gatgttcata tcttatttca attcactata caatccagtt
       61 cctaaaactt tgctagaaat tgatttggct ttccgaatta atttgttcag attttatttc
      121 atttcaatat actgataaat ccattcacta gcacagggca agagggagtc gctattaatt
      181 tcaacggtag caggtacata cagaggactc ctacctcaga tatactgcaa tatcattgta
      241 tgcaaaaaac ctctgagatt tttctcaaag gttctgattt tgctaattgc tgttctcaac
      301 cgctgcagta acaaaggcag tgtagagttc ttctggtcgg tttggacggc ttgacagttc
      361 agggtgatac tgacaagcta caaagaattt attttcagga atttccacga tttctaccaa
      421 acgattgtct ggagaaactc ctgaaaagac aaagcctgct gcctcaaact gctcacggaa
      481 ggcgttatta aactcataac ggtgacggtg acggcgttgc accacttctt gattgtgata
      541 agcagcagca gccttagagc cacgtttcaa cttagacgga taaagtccca aacgaagggt
      601 tccacccata tcctcaatat caatctgatc acgcatgata tcaatgatag ggtattttgt
      661 ttctggtgca agctctgcag aattggcacc ttcaagacct aaaacgtgac gagcaaactc
      721 gatacatgtc aactgcattc ccaagcagac tcccaacatt ggaacatcat tttcacgcgc
      781 atagcggatg gcttggattt tcccttctgt accacgttga ccaaaaccac ctggtacgat
      841 gatcccgtct gcatcagaca agagttctgc tacattctct gctgtcacat cattggcatt
      901 gacccaattg attttaactt ctgcatcatt gacatagcca gagtgtttca aggcttcgac
      961 cactgagata taggcatctt gcaactccac atacttacca acaagggaaa tcttaacttg
     1021 tttcttgagg ttcatgacct tgtccaccat ggctgaccat tctgtcatat ccgctgctgg
     1081 tgcgtctaat ttcaaatgat cacaaacaat ttggtccatc ccttgtgcct gcaagttcag
     1141 tggaatttgg taaagatgtt caacatccaa cgattcgata acggcttctg gtgccacatc
     1201 acagaactgg gccagtttat ttttaattcc ttgaccagct ggctcttctg tacgaataac
     1261 caacatattt ggttggattc ccaagccacg caattctttg acagagtgtt gggttggttt
     1321 ggttttcatt tcaccagcag ccttgaggta aggaagcaag gttgtatgga tatacatgac
     1381 attatccgca cccacatctg ccttcatctg acgaagagcc tctaggaatg gcaaggactc
     1441 gatatctcct actgttccac caacctctgt gataatgaca tcagagtcgg tcgttagagc
     1501 ggcacgcttg attttttctt tcaaagcatc tgtgatatga ggaatgactt gaacagttgc
     1561 cccaaggtat tctccacggc gttctttacg aagaacttca ctgtaaattt tcccagttgt
     1621 cacgttggaa tatttgttga gattgatatc gataaaacgt tcatagtgac ccaagtccaa
     1681 atctgtctca gctccgtcat ctgtcacaaa aacttccccg tgctggtaag gactcatggt
     1741 tcccggatca atattgatat aagggtcaaa cttttgaatg gttactttga gaccacgatt
     1801 tttcaagaga cggcctagac tcgctgccac aatccctttc ccaatggacg ataccacacc
     1861 accagttaca aaaatatatt tcgtagacat agattcctct ttctaaaatg ctcaaggtct
     1921 tgttaactac gaggggatat agaaaacaag accctactaa taagaataat ctgggacgac
     1981 tgcaccagat tcacaactaa tactcttcga aaatctcttc aaaccgcgtc aacgtcgcct
     2041 tgccgtagat atgtgttcct gactttgtca gtcttatcta caacctcaaa acagtgtttt
     2101 gagcagccta cggctagttt cctagcttgc tctttgattt tcattgagta taaaatacaa
     2161 gaagataact tcttgaaaaa acaaaaatag ctccctaaga actagggagc cccgacctct
     2221 aaaagaggtg cccaaacaat atgataccta aaaataggat aattgtcaat agctaactct
     2281 tattcctcgc tggtttcagc gtcgtcatct gaaaactcgt cgtcgtcttc gttgagatcc
     2341 acatcttctc ccaagtcatc tggagcgatt tcgttgattt ctgcatcata agcttccact
     2401 tcattttttt catcatctgg attttcatca tcgtatgaaa gagctggatc tgcttcgtat
     2461 gcatcttcgt cttctggatc atctgcattg tagtcaatgg catctgaatc accatccata
     2521 aaggcattga cacgtttttt cttagctttt ggtgctactt catcgtcgtc attttcttca
     2581 agagcgatga tttcttcgtc gatttcgtcc acaccatacc atgaacgaag accccatttg
     2641 ttgtccccaa gtgagatgaa gctaccgtca aagttcaact ctgtgtagaa caaaggcaaa
     2701 gcttcgcgga tatcgctgtt tgatgttcca aggtagtttt gaatttcgtt tacaagatcg
     2761 ctaaaatgca tctcatgatc gcgaccacga agttccaaga tagcacgcgc tacctcaatc
     2821 atagatagtt cacttttttc ttgcccagca aatacttcta attccaaagc gtttctcctc
     2881 atttatacta ctatcgccag agcgaacaga ctctgacctc attttatcat ttactcttta
     2941 ttttacgata attttgcgga atagtcaaag gttaaggggg agaaagtggc aggattagac
     3001 taattccaat ataaaactcc ttcctttttc tgttgctcca ttttccacaa atccaagcga
     3061 cttgaaacac ctcctagaag catgattgta ggtgtagatt tccttgactc tcaattcttt
     3121 ccatcctttt actcgagcca attcaatcaa agcacttaga atcttttttc caagtcctcg
     3181 atgttggtaa gcggaattcc caatcacaat ggggagatta tcctgagata gtgtaatatc
     3241 cccaattgga aaccattctc ccttctcctt gacttcaatc caaaaaagct caccatgccg
     3301 atccaaatag gaatacatgg cttccaaggt cgcttgactg taaggaagct tcaccccatc
     3361 tacgaggtaa accaagttca catcctgata ccaagcaaaa gcttcctcac aatgattgac
     3421 cttataataa ggaacaaaac acaatgcact accttttcaa caaaagagtt gctgcttgat
     3481 taaaaccatc acaccagtta taccattttg cttcataccc atcttgagct aggatacgat
     3541 cttctaaatc aaaaacagag taaatctttc tttcctcgca agcttgcgca tagagatgat
     3601 atagttcatc accaccatct ctatcccact cagcagaaat cgtatcccga cctgccaata
     3661 aagcctgata agccctgtga tgcccatctg taatcagcaa acaatctcca aaggcaagaa
     3721 tactgattgg atcgacttgg tttgtttctg ccgactggta aagcatctga atatcttgca
     3781 acttcttttc tgataaatat agttgagtcg gatgaagatc tgctatattg actttcattt
     3841 ctttctcctc aagggaattc gatactcact tctgtttgcc tttaaatcgc cattggaagc
     3901 ggagcttgtc atagaaggga aactcgataa acaggactcc caagcccaca cagagactgg
     3961 caaagacgtc tgatgggtaa tgaaccccca gatagactct tgataccagc acactgacta
     4021 ggtagaggcc aaggacgatt tgtacgattt ttctccagac tggattttta attcgttgac
     4081 tgagaatgac aatcagagta cctaccatca aagttacagc cagagaatgt ccacttggga
     4141 aggaaaatcc cttctcttcc accagatgta agatagctgg tcgtgggcgc tggtagatat
     4201 ttttaaaggt cacgattaaa agacctgcca aagccagatt tcccagcatg aagaaacttt
     4261 ctatcttcca tcgcttacga taaaagacaa aagctgtaat gacaacccaa gtgataatca
     4321 ctgggatatc aatcagacgt gtgagggctc gaaaaagaat agtcaaataa tctggtaagt
     4381 ctcctcgaat ggcagtctga atcgattggt caaaattgac caacatttca gggtaaaatt
     4441 tgaccatata gccaagaata acgaaaagta aaagggcaaa actgcccttc attaaaaatg
     4501 tttgtttatc tttcatagtg ttttaaggtt ggtttcaaaa ggacgtacaa caaccagaat
     4561 gaaacggaaa agattacacc ctcaatcaag ttaaaaggta ataccatggt cattaggtag
     4621 ttggaaagtc ccaaaatttt tccaatatca aagttagcaa acttagcgta caaaggaaca
     4681 gcataaacat agttgagaac caacatggcc aaggttaaac caacagttcc agctagagag
     4741 cctagtagga aacgaagggt tgtccgttcc tttttccaaa tcaaagcaaa tacgatgaca
     4801 aaaactccca aagctacgat attcatcggc aaaccaatgt aagtattcac tccttggctg
     4861 ttaagaagca atttcaagag tgagcgaagc aagagcactc ctagagcagc aggcaaatcc
     4921 atgaccacca gacccacaag gactggcaag atactaaatt cgatcttgag gaaagatgcc
     4981 gctggtaaaa gcggaaagtc aaagtacatc agcacaaatg agatggctga taaaattgca
     5041 atggtcgaaa gtcgacgtgt gtttgtcata acaggttcct ccaattttct ataaaatcag
     5101 aagaagttgg aaaggattcc tctatctatt ctcacttttt atatcccaaa agttccctct
     5161 tactctatta aagaaaaaca aagcaagtgg ttacaatccg gctataaatc tatcaaaaca
     5221 gacaaagcta ttctttcgtc ttctcccatc cagactatac tgtcggttgt ggaatctcac
     5281 cacatcagct tgcgctcgcg gacttcttta aagagaagga aatagagatt tttcttttag
     5341 actaggcgac aagctgtagg cataacttct ggttaggcaa agcttgtcaa caaagtataa
     5401 aaggaaaaga tcatttccta gttaaagtca ccgccggtcg ggaatcacac cctgccctga
     5461 agactctttt atcataacaa aaaacgcttg caagcgcaag cattttgttc attttcattt
     5521 tttatttcaa tttatccact tcataggtat ggacgagctc aagacctgca aagttctgct
     5581 ggcgaagagc ctcatagaca atcatgcaga cggtattaga cacattgaga ctgcggacat
     5641 gttcatcatt catgggaata cggagagcct tctcaggatg ttctcgcata aaatcttcag
     5701 ataagccctt gtcttcacgt ccaaagagaa aataatggtc ctcgtcagtc gataaatcca
     5761 cctcagaata gactttttcc gcgaatttcg aaatcagata gagttttccc ttcatctgag
     5821 atatgaaatc ttccaaactc tcgtaaaaat aaatctctag cttatcccag taatccaatc
     5881 cagcccgctt catcttgcgg tcatcaatag gaaagcccat aggcttgatg atgtggaggg
     5941 gagaattggt cgcagcgcaa gtacgcgcga tattgcccgt attttgtgga atttgaggtt
     6001 caaataatac aatgtgattt gtcatgactt gcttcctttc accattgcaa aaaaatagcc
     6061 acactgcccg gagtcaagct cagcaaacag cgtggttaag gcatcgttaa cttacctcac
     6121 aacaggtttg aagtaaatca gcgaaactac tttcttagta taacactttc agaatcattg
     6181 tcaatagaaa tgacttgatt ttttcaattt tttcaagcta tttccaaggg ttgtaaaatc
     6241 gtccctgatt ctgcaagata agtagtaaac taactactaa aaacaaggtt gccaagagca
     6301 aggtaatata gtctcctttt ttcaaggcct gataactata ccatgtgcgt tttttctctt
     6361 tcccaaagcg gcgaagctcc atggcagtcg caatggtatc aatgcgttct agcgagctaa
     6421 aaatcaaggg cgtaataatg agcagattgc ctttgattcg ttgcataaga gaagctttct
     6481 tggataattc catcccacgc gcctcctgag acatcttgat agtaaagaat tcttcctgca
     6541 aatctggaat atagcgcaag gtcaggctga cagaataagc aatcttatag ggcacaccaa
     6601 tttgatttaa actggaagca aactgactag gatgggttgt catcaaaaag ataatagcca
     6661 gaggaatggt gcaaagatac ttaatggcca aatttagcag ataaaagagc tcctggctgg
     6721 ttagagtgta gacaccgatt ccctgccaaa tcacacttct ctctccataa agtccaaccc
     6781 catactcggg agaaaagaga tagaccatca aaacgtttaa aacggcaaat accgtcgcaa
     6841 aaacggctac aaaggaaaca tctttaaagc gaatttctga taaatagagg agaaagactg
     6901 aaaagatggc aatcagcaag agcattctgg tatcatagct aatcatggcc gccaatgata
     6961 ccagaatgaa aaagagaagt ttcccagctc ccgacaagcg atgaatcaca gtatctctat
     7021 gctggtaacc gattaattta gcttgcatcc ctctctcctt tctttgtaaa atgccgttaa
     7081 atccagtgga tccacatcta gtttcttagc caagttaaag atggaggttt cttttagatt
     7141 ggcttttact aacagctcag gatcgctcaa cagactggct ggaacagtat cggcaatcaa
     7201 ttctccatcc accatgacaa ggacccggtc tgaataatcc agcatcaatt gcatatcatg
     7261 ggtaatcatg acaatggtat gccctttttg atgtaactct tcgagaaatt ccataatctc
     7321 agtatagttc ttctgatctt gacctgcagt cggttcatct aggagaataa tttcagctcc
     7381 taagaccaaa attgaagcaa tggtgacacg ttttttctga ccaaatgaca gggcagaaat
     7441 aggccaatta cggaattcat aaagtccaca gattttcaag gtttcataga ctctcgtttc
     7501 aatttccttc tcatccacac ctcgcaaacg gagccctaga gccacctcat caaaaatcat
     7561 attggttgaa atcatttgat taggattttg tagcacatag cctactcgtt ccgcccgctc
     7621 tgcaacagaa tcgcctttta tatcctgttt ttcccaaaga tagcgtcctt ccgtctgaat
     7681 aaagctactt atagccttgg ctagagttga tttccctgct ccattttttc cgacaatagc
     7741 aatcttttca ccctttttaa tatctaaatg tagggatttt aaaatcggtc tatcatcata
     7801 agagaaagac acgtcctcta atttaaagag tgactgcaat tctggagttt cttttgccag
     7861 ttcattctgc agctgaacct gaccttttga gatagacatg ttatccagat tcgctaactg
     7921 ttctttcttg actaagtcca cacctaattg acggagagtc gttagataaa ggggttctcg
     7981 aattccattt tgagtcaata aatcagttgc aagcaactgg tcagggctcc cattaaaaag
     8041 gatacgacca tcgtttatca agacaatccg atccacaggg cgatgcagaa catcctccaa
     8101 acggtgctcg ataataagag tcgtcgtccc ctcttcctta tgaatctggt caatcaattc
     8161 gataatatcc tgacctgact tgggatctag attggcgagt ggctcatcaa acaagagaat
     8221 cggactttca tcaatcaaga caccagccag actgactcgc tgcttttgtc cacctgacaa
     8281 atcctgaggg cgctgatcca gtaaaggaag aaggtccagc ttttcagccc atttataaac
     8341 acgacctttc atctcatcta gggctgtcac atcattttcc agagcaaacg ccaaatcttc
     8401 tgccacagac aagccaataa actgcccatc tgtatcctgc aaaactgtgc taaccagatg
     8461 agacttatca tagatgctca tatcaaaggc tgtttgaccc tttatcaaaa attctccata
     8521 tgtctgaccc ttgtaaatat tgggaataat cccattcaaa cactgaccca aggtagattt
     8581 acctgatcca gatggtccaa caattaagac tttctctccc ttgtaaatgg tcaagtctat
     8641 cccttgcaag gtcggttctt gttgtgtttc ataccggaaa gagaaatcct tccactcaat
     8701 tatagcttct ttcatcttac tctcttcatt cgcttcttag acttctattt tatcataaat
     8761 caagcccttc ttgcagtctc tcctcttaaa atcttagcgc caaaaagatt cctatcctag
     8821 cttacttacc taactaatct ataaacatcg aaaaagacta gttgcccagc cttccccatc
     8881 attttatact cttcgaaaat ctcttcaaac cacgtcagct tcgccttgcc gtaggtatgg
     8941 ttactgactt cgtcagtttc atctacaacc tcaaaaccat gttttgagct gacttcgtca
     9001 gttctatcca caatttcaaa acactgtttt gagcaacctg cggctaactt cctagtttgc
     9061 tctttgattt tcattgagta ttagtccttt ttcaaacttc ctgcacgagt ttgggttcct
     9121 gcataggcaa gtaagagaag agttcctgca atagctacag atacaccatt ggcaattccc
     9181 gcaacaatcc cttgtgcaaa tactttttct gccgcttctt gataaatcac aacatctcca
     9241 agtggtgcca agacacccca aacaagggca tttgcaagta gttgaatgag gttaaaaata
     9301 agaatatctt tccagtcaaa aacaccattg atcacgcgaa cgtactttct aaaaagtccc
     9361 acaactaaac caaagagtcc gctagcgata atccaagtcc accatagacc ataaccagca
     9421 agagagtcct tgattgcatg accaatcaac ccgacaagca aaccgataat cggtccaaaa
     9481 ataatagaaa gtagcgcttg taccgcatac tgaagctgga tgcttgtatt tggaacaggg
     9541 gttggaatgt tgatcatccc gatgacgaca aagagggcag cgccaattcc gacagcaaca
     9601 acttgtttaa ttgtaaattt aatttccata ctattctcct attttatcct tctattttct
     9661 ttatttcaat ggtccaagat gaaccgacac ctacattata ggccttggca aaggaacctt
     9721 ggttgatagc caaacctaaa cgatagagag agttgatgta aaggatgggt tgcccaattc
     9781 tcacatctgc aaatgatttg ccatagacaa cctgattttg atagaccagc atatcagcat
     9841 gatagatggt cacttcaaaa cgatcaccaa attctggttc cagcttgtaa aattcttccc
     9901 gtgtgataga ggtccaaagc gaaccgaaac gcacatccag aatatcaatg gctcccttca
     9961 ccagatgatc ttctatgatg gtcgctacga ctggaagctc tacaatctgt tccacactga
    10021 gctctggccc tacttcctca aaagtaatgt gaccactggc cagtttagca ccagtatagg
    10081 catagacatc acgaccgtgg aaggtataag aatgctctgt gttttgacgc ctattggcca
    10141 cctcagaaat ctcacgaatg gctacaatgc caacgtgttt cttgataaag gaaagcgtcc
    10201 cattatctgg cgtgacaatg tattgatttt ttgcagtctt ggcaactaca ctcttacgtt
    10261 tcgaaccgac acctggatcg acaaccgata caaacgtcgt tccctcaggc cagtaatcca
    10321 ccgtctgaaa gagacgatag ctcccctcaa aaatattata aggcgtgata tcgtgcgtca
    10381 agtgatggat ttttaaggtt ggagactctt ctaaagccac tccaatcata gccgacaccg
    10441 caccatcaac cagaccaaag tctgattgta ataccagtaa attattgttc attttatctc
    10501 cttgtatatc ctttatcata ccatatttca gagaaagtcg ctaatagcta tttcaattgg
    10561 ttagggtata gttttacctt atagcgaatt ttcactaaaa gctcttgtta ttagctagta
    10621 ggtgcatttt ttcttgaaaa agggtatgat agttacatca tgaaaaagta ggttttatta
    10681 tgaaaattat ccttgtcgga gggggaaaag ttggttttgc cctctgtcgc tccttggttg
    10741 cagaaaagca tgatgttttg ctgattgagc aagacgaagc tgttctcaat catattgtca
    10801 gtcgctttga tatcattggt atccttggta acggggccga ttttgccatt cttgagcaag
    10861 ccagcgtcca agattgtgat atctttatcg ccctgactga gcacgatgaa gtcaacatga
    10921 ttgcagcagt tctagccaag aaaatgggag ctaaagaaac tatcgttcgg gtgcggaacc
    10981 ctgaatattc taactcttat ttcaaggaaa agaatattct cggtttttct cttatcgtta
    11041 atcctgagct cttggctgcc cgtgctatcg cgaatatcat tgacttcccc aacgccctgt
    11101 ctgtcgaacg ctttgctggt ggacgcgtta gcctcatgga atttgtcgtc aagtccacca
    11161 gcggtctttg ccaaatgccc atttctgatt ttcgtaaaaa atttggtaat gtcattgtct
    11221 gtgcgataga gagggatcat caaattatca ttccaagcgg tgacatgact gtacaggata
    11281 aagatagaat ctttgtcact ggtaaccgtg tcgatatgat actcttccat aattatttta
    11341 aatcacgcgc cgtgaagagc cttctcatcg ttggggcagg tagaattgcc tattatctac
    11401 ttggtattct caaagatagt cgtatcgata caaaagtcat tgaaatcaat cctgaaatcg
    11461 ccagcttctt tagcgagaaa ttcccaaatc tctacatcgt tcaaggagat ggaaccgcaa
    11521 aagatatcct gctggaagaa agtgctcaac actatgatgc cgttgcgact ctaacaggag
    11581 tcgatgagga aaatctgatt acatctatgt tccttgacag ggtaggtgta cagaaaaata
    11641 ttactaaggt caatcgtacc agtctcctcg agattatcaa tgcgcctgat ttttcaagta
    11701 tcatcacacc taaaagcatc gctgtagata cgattatgca ctttattcgt ggtcgagtta
    11761 atgcccagta ttcagacctt caagccatgc accatctagc caatggccaa atcgaaaccc
    11821 tgcaattcca tatcaaggaa gccaataaaa tgactgccaa acctctttct caactgaaat
    11881 tgaaaaaaga ggttcttatt gcagccatta ttcgaaaggg caagactatt ttcccaactg
    11941 gggaggatat gttggaagtt ggagacaagc tcctagtaac aaccttgttg ccaaacatca
    12001 ccaagattta tgacttgatt gcgaggtaag aaatgaataa aagtatgatt cgttacctcc
    12061 tttcaaagtt acttttgatt gaagctgttc tcctcttggt tcctgtggct atcgctgtct
    12121 attaccgtga atcgagccaa gtctttacag ccctcttttc aactataggg attctcgtat
    12181 tgttaggcgg ttcagggagt ttacagaagc caaaaaatca acggatttat gccaaggagg
    12241 gagtcttgat cgttgccctc tgttggatcc tttggtcttt ctttggtggt ctcccctttg
    12301 tcttttctgg gcaaatccct agcgttattg atgccttttt tgaaattagt tctgggttta
    12361 caactactgg agcaagtatt ttgaacgaca tttcggttct cagccgttcc ctcctcttct
    12421 ggcgaagttt tacccacttg attggaggga tgggagtgct tgtttttgca cttgctatta
    12481 tggacaatgc caaaaatagt cacctagaag taatgaaggc tgaggttcct ggtcctgtct
    12541 ttggtaaggt tgtatccaaa ttaaaaaaca ctgcccagat cctctatctc ctttacatag
    12601 ccctcttttc cctctttgtc atcatctatt atctagccgg tatgcctctc tacgatagtt
    12661 ttgtcattgc tatggggaca gcgggaactg gaggatttac cgtctataac gatggaattg
    12721 cccactatgg tagctcactg attacctatc tggttagtat aggagttttg gtttttgggg
    12781 taaatttcaa tctctactac taccttatgc tccgtcgggt taaggccttc tttggagatg
    12841 aagagcttcg ggcttacttg gtcatcgtgc tggtttctac aggcttgatt accctcaata
    12901 ctctctacct ctacccagga ttttccaaaa gctttgaaat gaccttcttc caggtttcca
    12961 acatcattac aacaactggt tttggatatg gagatattac caactggccc ctcttctccc
    13021 agtttatcct cctcttcctc atgacaatcg gtggttctgc tggatcaact gcaggtggac
    13081 tcaagattat tcgaggcctc atcctttcaa aaattgccaa aaaccaaatt ttgtccattc
    13141 tatctcccca ccgtgttttg actctccatg tgaataaaac ggtgattgat aaggataccc
    13201 agcataaaat tctcaagtac tttgtcatct atgctatgat tttgctagcg cttatcttta
    13261 ttgtcagcct agatagcaat gattttctgg tcgtgaccag cgctgtcttt agctgtttca
    13321 ataatatcgg gcctattcta ggaaccactt ctagtttctc aatctttagt cccatctcaa
    13381 aaattctcct atcctttgca atgattgcag ggcgcttgga gatttaccca atcctccttc
    13441 tctttatgaa gagaacttgg tctaagagat aaaatacaaa atccctcttt tta
//
LOCUS       DAVLZS010000047        13215 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLZS010000047 DAVLZS010000000
VERSION     DAVLZS010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.047"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(4..849)
                     /locus_tag="VYO88_001612"
     CDS             complement(4..849)
                     /locus_tag="VYO88_001612"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1719680.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKACAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGPLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            1105..2132
                     /locus_tag="VYO88_001613"
                     /pseudo
     CDS             1105..2132
                     /locus_tag="VYO88_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(2433..4322)
                     /locus_tag="VYO88_001614"
     CDS             complement(2433..4322)
                     /locus_tag="VYO88_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1719681.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            4460..6025
                     /locus_tag="VYO88_001615"
     CDS             4460..6025
                     /locus_tag="VYO88_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1719682.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            6025..6765
                     /locus_tag="VYO88_001616"
     CDS             6025..6765
                     /locus_tag="VYO88_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1719683.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEILKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(6874..7089)
                     /locus_tag="VYO88_001617"
     CDS             complement(6874..7089)
                     /locus_tag="VYO88_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719684.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(7960..9210)
                     /gene="ilvA"
                     /locus_tag="VYO88_001618"
     CDS             complement(7960..9210)
                     /gene="ilvA"
                     /locus_tag="VYO88_001618"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1719685.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(9260..9400)
                     /locus_tag="VYO88_001619"
                     /pseudo
     CDS             complement(9260..9400)
                     /locus_tag="VYO88_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
     gene            complement(9585..9821)
                     /locus_tag="VYO88_001620"
     CDS             complement(9585..9821)
                     /locus_tag="VYO88_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719686.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     SREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(9928..10950)
                     /gene="ilvC"
                     /locus_tag="VYO88_001621"
     CDS             complement(9928..10950)
                     /gene="ilvC"
                     /locus_tag="VYO88_001621"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1719687.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPSLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGLRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(11016..11492)
                     /gene="ilvN"
                     /locus_tag="VYO88_001622"
     CDS             complement(11016..11492)
                     /gene="ilvN"
                     /locus_tag="VYO88_001622"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1719688.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(11485..13185)
                     /locus_tag="VYO88_001623"
     CDS             complement(11485..13185)
                     /locus_tag="VYO88_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1719689.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
BASE COUNT         4043 a         2991 c         2312 g         3869 t
ORIGIN      
        1 ttcttataca aataaacgga caaaactgta aagtagcaaa acactaccaa gcacgatacg
       61 gtatttacca aaaagggtga agtcgtgttt tttcacatag ctggtcaaga agcgaatagc
      121 caccatgctg accgcaaaag ctactcccat cgcgaccaag agcaaaaaca atggcccaaa
      181 gctcaagagt tctccggctt tcacaaattt gaaaatcttt aaggcactag ctccaaacat
      241 aacgggaatc ccaagataga aggtaaattc tgtcacaact gaacgactgg ttccatttaa
      301 caaaccaccg acaatcgttg cacctgaacg gctagtccct ggtaaaagag caagaacttg
      361 gaagagtccg atatagaaag cggtcgtata aggaagcttg tccaactctg ttacacttgg
      421 ctcgatagca cacgctttat tgcgcttttc caaatagatg aaggcaaccc cgtagataat
      481 caacatgaga gcaactgaaa ccatgttatg gaagtgggta tcaaaccaat catcaaattt
      541 aaagacacca agtaaaggta aagtagcaat caagaccttc aaccatagtc tccaagtctt
      601 acgaacttcc tgtttgtcct tagtcggttt aaaaggattg agcttgttaa aataaatcac
      661 cataactgct aaaatagcac caagctgaat cacgacatta aacatggaca taaaggcttc
      721 attttgattt tggtattgga taaactcctc tgctaaaatc aagtgacctg tactggaaat
      781 cggcaaccat tccgtaattc cttcaacaat cccgaagaag atagatttta aaatttcaat
      841 aagatacata tatttctcct tatattatat ttaacgcagt tagctactgc caaagcccaa
      901 gtggtatact tggaataagc cactgtggat tagttcattt cctccaatcg cttgacgatt
      961 tccgaaagga tctaaccaca gctttttgtt tcaattggta atgagtttga taacgcatag
     1021 acgttttatc tcgtctaagg taacaaggca aaaagttcgt ggataaccaa gtagacttga
     1081 aatactatat ctggaggtac tcccatgctt tatgtgggca ttgatgtcgc taaaaataaa
     1141 cacgatgtta cagccttgaa tgttcgagga aaactgttct taaaccactc actttttcaa
     1201 ataataaagc tggttttgaa ctattagatc tgtctcttcg acagctcaac caagactgtc
     1261 tcatcgctct tgaagatacc ggacattatg cctttaatct actgaacttc ctgcatgaac
     1321 aaggatataa agtttacacc tacactcctt tgctcatcaa ggaatttgcc aaatcattat
     1381 cacttcgcaa gactaaaacg gataagaaag acgctcatgg catcgctctt aaacttcttt
     1441 ctgaccccaa tcgtgaacaa tttcaacacg ataatcggca agtagaacta aaaatactgg
     1501 ctagacatat tcatcgtctc aagaaaaaac agtctgattg gaaagtacaa tacactcgtt
     1561 gtcttgatat catctttcct gagttggata aaatcgttgg aaagcattca gaatatacct
     1621 accaactctt gacatgctac cctaatcctc agaaaaggct tgaggcagga tttgataagc
     1681 tgatagaaat taagcgattg accgcttcta aaattcagga tatcctctca gtcgcacctc
     1741 gttctatcgg aacaacatct cctgctcgtg aattcgaaat catcgaaaac atcaaacatt
     1801 acaagaggct cattgacaag gcggaaaaat gtgtcaatga cttgatggct gagttcaact
     1861 cggtcatcac gacggttact gggattggga atcgtttagg ggcggtcatt ttagccgaga
     1921 ttcaaaatat tcatgccttt gataatcctg ctcaattaca agctttcgct ggactggatt
     1981 cttctattta tcagtcaggt cagattgatt tagctggaag aatggtcaaa cggggttctc
     2041 ctcatctgcg gtgggcactc atacaagctg ccaaagcatg cgctcgcttt tcacctgctt
     2101 ttaaggccta tcttaagact aagttagaat aagaaaaaca ttacaatgta gccatcatcc
     2161 accttgcaaa aaaacttatc cgaaccctgt tttatatcct aaaaaagagc tgccatttga
     2221 cgaacaaaaa gtgatgtaat ttctgaaatc aacacaggat tacctttgaa aaaatggact
     2281 ttttcaaggg ctttttgccg tgctctaaaa tcatcgccaa atcatcaaat tgaaataaga
     2341 aatagtttag ataaaattat tgacttttct tatagtttgt ctttcttcta tcttccatta
     2401 tatcatactt tttcagtcta tggtagctct ctttaaaagg ctccgatact gccgccacct
     2461 ccgcctccag agaagccacc gccagaactt ccacttccag aagatacgga gtaggtactt
     2521 gctgtatttg cgacactagc ataatggctc atttgcgcgc ttgaatgata aaacatactg
     2581 tgccagccat aagctacata gagattgata tctggatttt caacttgaat ctgatgaacc
     2641 ttcatcaaat gactaacctt gtccgcatag ccaaataagg ttgcatagac caagagacga
     2701 ttccaaacaa caatactttc caattcagcc ttatccagtc gtgcaatctc acgtaacata
     2761 ttttcaaaac tggtccagag atagtagacc tcagctcccg cttcatttag aacaccatca
     2821 cgattatcta gtcgaagctt ccaataatag aaaacagaca aaactaaccc tagaaaacca
     2881 agtattggca aagggaggta aagatagcca tgaacgtcta aactgtacaa gaacaaacca
     2941 aatccgataa ataggggcag gatagtcaag gcacccatac ccacttgcaa ggccttttcc
     3001 ccaccagtta aaggacgata ataatctggg agcccccaga aggaaactcg ttttctcact
     3061 ccttcttgca tctggttcaa tacctcttca aaagaagatt tgagttgaag ccctcttgct
     3121 tgaatccgtt tttcatcaga aactttggct ctacgataaa gactatcaga taccttgtaa
     3181 tccgcaaaca aattggaaag agtttcttct tttttacctg aaaaagctag atttaggcag
     3241 tctttctcaa agcttgacaa accatcttct tttactagcc tcaaaccaac tgcatctcct
     3301 tctgaaatga tagagacatt cccacggtct atcacatcta gcaaggtagc ttgaataagt
     3361 tgatcaaagg tgaattttcc agctcccttg accaagggac tcacttcctc caaggaggtc
     3421 gagtagactg cttctgataa aaccataggc tctaattcca ttgggggttc atagagacga
     3481 tgatttttag catatttgat tgaaggagcg gtctttcttc tatagataaa atagaaacag
     3541 atgctcaata acaaggagat ggaaaggatc gaagggaaga tccaagtaag tagttgttta
     3601 ctttgatctt tttctttaac gatcgaatcc tctatcttat taaactcttc taaacgattc
     3661 cctttcaagc cctgatccct agcgctagca aaatcagttc gcggccagta ggcatgcaat
     3721 tcaactccac gcttagccgg aagattgtct aaacgaatag tataatcaag gttactcttt
     3781 tcaaccgttc tctctctaaa aagtttccct gtatggaaaa agagtttctc agcccccttg
     3841 tctcccctta catgaaattc aaacttttca atagactctg aactatctgt cagaggttgc
     3901 caatttaatt cagcgatatc atcataaagg aaaagtaaat tttttaagtt ccagacgagg
     3961 tcaacttcaa ctatgtcgcc ctcctgacct ggattataga ctctcacagt ataaccatcc
     4021 gcttcttctg ttacttcgct agtcacatct gctagttctg caccgttttt cgcggcctga
     4081 atctttggat gagggtcaat gtcaaacccg ctaggcatct taccagcacg tccaagtccc
     4141 acgatttggc ccttaaagtc ctcctcaaac tggtaaacta tcttctgtct aaactctgcc
     4201 gtattgtctg catgaatata caaatcccct tgataagagt ttatcttgaa atcaatggca
     4261 aaaacagaga gtggaagaag gcaaaacaag cctaacacca gtaagaaaaa agtttttttc
     4321 atcaactaag cccccttttt atctttctta tcattatagc attttttcgt aagtaaaggc
     4381 ttacttatgt tgaaaaatta cgcatttttc gataaaatag gagacagtta ttttttaata
     4441 gatcagaata ggagaaatca tgagaaaaat atacttatct attttcacaa gtctcttgct
     4501 gatgctagga cttgtcaatg ttgctcaagc cgatgaatat ttacgcatcg gtatggaagc
     4561 agcatatgct ccctttaact ggacccagga tgatgatagc aacggagctg tcaaaatcga
     4621 tgggaccaat cagtatgcca acggatacga tgttcaaatc gccaagaaaa tcgctaagga
     4681 cttaggtaaa gaacctttgg ttgttaaaac caagtgggaa ggtctagtcc ctgcccttac
     4741 ttctggtaag attgacatga ttatcgcagg tatgagtcca actgcagaac gcaaacaaga
     4801 aattgccttt tcgagcagtt actatactag cgaaccagtt ttgcttgtca aaaaagattc
     4861 tgcctacgca agtgctaaat ctttggatga ctttaacggt gcaaaaatca cttctcaaca
     4921 aggggtctac ctttataact tgattgcaca aatcccaggt gctaaaaaag aaacagccat
     4981 gggagacttc gctcaaatgc gacaagctct tgaggctggt gtcattgatg cttatgtttc
     5041 tgaacgtcca gaagcactga ctgctgaagc tgcgaactct aagttcaaga tgattcaagt
     5101 agaacctggt ttcaaaactg gggaagaaga tacagctatc gctatcgggc ttcgtaaaaa
     5161 tgacaatcgt attagccaaa tcaatgccag cattgaaacc atttcaaaag atgaccaagt
     5221 tgccttgatg gatcgtatga tcaaggaaca acctgccgaa gctacaacaa ctgaagagac
     5281 tagcagtagt ttctttagcc aagttgctaa aattctttct gaaaactggc aacaactctt
     5341 gcgtggtgct ggtatcactc ttttaatctc tatcgtcgga accatcatag gtctcattat
     5401 tggacttgcc attggtgtct tccgtactgc tcctctctct gaaaacaaag tcatttacgg
     5461 cctacaaaaa ctagtcggct gggttctcaa tgtctacatt gaaattttcc gtggtacgcc
     5521 aatgattgtt caatcgatgg ttatctacta tggaactgcc caagctttcg ggatcaacct
     5581 tgaccgtaca ctggctgcta tcttcatcgt ttcaatcaat accggtgcct acatgactga
     5641 aatcgtccgt ggtggtatcc tagcagttga caagggacaa tttgaagctg cgactgctct
     5701 tggtatgacc cataaccaga ccatgcgtaa gattgtccta cctcaggtag tccgtaacat
     5761 cctacctgca actggtaatg aatttgtcat caatatcaaa gatacatctg tattgaacgt
     5821 tatctctgtt gtcgaacttt atttctcagg aaataccgtg gcaacacaaa cctatcaata
     5881 cttccagaca tttacaatca tcgccgtgat ttactttgtc ctcaccttca ccgtaacacg
     5941 tatcctacgc tttatcgagc gcagaatgga catggatacc tacactacag gtgctaacca
     6001 aatgcaaacg gaggatttga aataatgaca caagcaatcc ttgaaattaa acacctcaaa
     6061 aaatcctatg gacaaaacga agtgctaaaa gacatttcac tcactgtcca caagggagag
     6121 gtcatctcta tcatcggaag ctctggaagc ggaaaatcga ccttcctacg ctccattaac
     6181 ctacttgaaa caccaactga tggacaaatc ctttatcatg gacaaaacgt cctcgaaaaa
     6241 ggctatgacc tcacgcaata ccgtgaaaag ttggggatgg ttttccaatc ctttaacctc
     6301 tttgaaaatc tcaatgttct tgaaaacaca atcgtcgctc agacaactgt cctaaaacgc
     6361 gaacgcacag aagctgaaaa gattgccaaa gaaaacctgg aaaaggtcgg catgggagaa
     6421 cgctactggc aagccaaacc aaaacaactc tcaggtggtc aaaaacaacg tgtggccatc
     6481 gctcgtgccc tctccatgaa tccggacgct attctctttg atgaaccaac atcagctctc
     6541 gatccagaaa tggttggaga aatcctcaaa atcatgcagg acctggctca ggaaggcttg
     6601 accatgattg tcgtaaccca tgaaatggaa tttgcccgtg atgtctctca ccgtgttatc
     6661 tttatggata agggcgtgat cgctgaagaa ggtaaaccag aagacctctt caccaatcct
     6721 aaagaagacc gaacaaaaga gttccttcaa cgctatctca aataaaaaga aaaggctgca
     6781 tcaaccgtgc agtctttttg ctgtcctcaa aatgaaaagg cagattctct atctctacta
     6841 cttgaaggtc aagaatccgc cgttatccaa agattaatct tcaaattttt cataattttt
     6901 ttcatagaaa tcaattaggc ctagggctgt ttcaaatgaa atatttttta cttttgcacg
     6961 accctgcgcc agagcaatga tagacatttc acgcgcattc gtttctttag agatacggta
     7021 gcctgtgatt ttcttatcac gaacccagcc aacaactgat tctacttttt caaagtttga
     7081 cttagccatg tttttctcct attttcttct ttataatatt taattgtata cgtttttact
     7141 acttttgtca ataaaaaaaa catatattca acgaaaataa ttagttcaga attttcttac
     7201 ttccttttta aatccgataa tatataggtt ttgctagcct ctacaccata aatatttgct
     7261 aataaaaata ctgtattatt accctcttaa ggtgcgaaat tattcaagtt cttaaaaaat
     7321 gcttctctat ttccgtaaga tagcttattt cttcgattta agaactgaag atgatagttc
     7381 taacctttag aaatccaagc cttcactagc tcaaaaactc ctatctttct tcctcaataa
     7441 atcatctgag agataggtat tccttatatc cttcaaattc atcactcctt tggatattga
     7501 ggtgctagcc tagaagcaga cacccgatta tctaaaccat ccttaataaa gatgacaaga
     7561 cagataaact cagttaatta cttatatatc cttttaatat ggtatatttg tcaacaaaaa
     7621 gaaatcaaat cataccttat actcaatgaa aatcaaagag caaactagga agctagccgc
     7681 aagttgctca aaacactgtt ttgaggttgc agatagagct aacgtggttt gaagagattt
     7741 tcgaagagta ttaaagacag tgtgactatg cttgtcaata gataggaaat caaaatgaag
     7801 gatggaaatc tgagccaaac atcataagtg ctataatgaa cagaagtaag aattgcacga
     7861 taagttttct aaaaccatag gaatcgtccc ctttcttcat cttcattata gcacatatac
     7921 atcagttgta caaataatat gatatttttt tattagtcct cagacaagca tattataaag
     7981 cgtttcatta ccatttaagt taatataagc tggatcaaaa ccttccattc tacggatcaa
     8041 acctgcataa tcatgcttat ctgccaaagc gatcccaatc aatactgggc ctgttccctt
     8101 gctagctcgt ttgatatact caaaacgtgt gatatcatca tttggcccca ggatatcatt
     8161 tacaaactca cgcaaagctc ctggacgctg tgggaaattg accacaaagt aatgtttgat
     8221 accatcataa atcaaggcac gctcttccat ttctggcata cggttgatat cattatttcc
     8281 tccagaaatg atacaacaaa tggttttccc cttaatatat tcagctaaaa cctctaaaga
     8341 ggcgatacta gccgctccag caggttctgc gactatccct tgcttagagt aaaggtcaat
     8401 caaggtttca gaaatcaatc cctcatcgac acctaccaaa gtttgaatat gttgacgagt
     8461 tgcttcatag gtcaactgac ctaccttttg cacagcaatc ccatccgcaa atttatcaat
     8521 ttccttgagt ttgactggac ctccagcctc aaaggcagct ttcatggaac gcgctccatt
     8581 cgcctctact ccgataacct caatctctgg acttgtttcc ttgatatagg tagaaacccc
     8641 ggcaatgaga ccgccaccac caacaggaac caagacagca tcaaaatcaa tcgattcttt
     8701 tcgagcttct tctaaaatct cataagcaac tgttccttga cctgcttgaa catgagcatc
     8761 atcaaaagga tcaataaagg tacgattttc agagactgta aattcttgag ctgctttggc
     8821 tgaggcatca aaggtatctc caactagttt aatagttaca aaatccccac caaaaaagcg
     8881 aacctgacca atcttttgtt gtggcgtagt aataggcata aagatagtag caggaatttt
     8941 catttcatta caagtatagg ctactccctg cgcatgattt cccgcagaag cgcagactac
     9001 cccacgttca cgttcttcct tgctgagctg ggaaatggca taataggcac cacgaatttt
     9061 aaaggagcga acacgctggg cattttcttt tttcaaataa atcttagcac catacttctc
     9121 cgataaataa tgatcgtaat ccagtggagt attcacaacc acaccgttca agaccttgtg
     9181 agccttgatt atatcttttg aacttaacat ataaaacctc tttttctata aaaaacagtc
     9241 actaatgact gttttttagt tattcatctc cgaaaacttc agtaacactt tcatggtatt
     9301 tatgagccat acgaatcgaa aactctttag gaagttcata acgatttgtg gaaatccaat
     9361 catataacca ttctaccaaa ctttcttcac tatcattacg aaagttttcg cagtccagtc
     9421 atttaaaccc gattctttca atccagatgc aataatttgc tctatttgat ataaaccgcc
     9481 atctatcgtc tcatttattc tgcgaagagg accttcaata taggataaag cttctccgaa
     9541 tctaacagct gatttaggtc ctaatgattt accaactata tttgttaatg ttttttattt
     9601 ctcaaaatcc atttcgctat ataacgagca gatttagtcg caccagctct ctcaaacgga
     9661 gaatgaattt caagaccttc ttctctagat atttgtgcca atttgaagaa ttgttcaaag
     9721 ttcatatgca acctaccatc ttcaaaatta gcatcatcat aaatgttaat tacagcattt
     9781 tcatcatacg accaatctgc tttattttgg tctgctagca ctattaccga cggtgtaatt
     9841 acattataca actagaacca ataataacga tgcaattttt ctcataatct ttttcataaa
     9901 atcatctcca gcgctatata tttctaatta gttatagatt ttgaatgcat catcgtcgtt
     9961 tttaccaacg aatggcattg ctttacgcaa ttctgcacca actttttcaa tttcaaggtt
    10021 agctgcttgt tcacggtaag cagtcaattt tggacgtcca gctttatagt catttacaaa
    10081 gtcatttgca aatttaccat tttggatgtc tgccaagaca gccttcatat tttctttaac
    10141 ttgttcagtg attacacgta gacctgatac atagtcaccg tattcagcag tgtttgaaat
    10201 agattgacgc attttcttga atccaccttc gtagatcaag tcaacgatca atttcatttc
    10261 gtgaagaact tcaaagtaag ccaattctgg agcgtaacct gcttctgtca agacttcgaa
    10321 acctgcttcg ataagggcag tcaaaccacc acaaagtaca gcttgttcac caaacaaatc
    10381 ttcttcagtt tcttctttgt aagttgtttc aagaagacct acacgagccg ctccaacacc
    10441 tttacaccag tccatagcaa tgtttttagc atttcctgtt gcatcttggt atactgcata
    10501 aagagctgga acaccaaatc cttcttcgta agtacgacgt accaagtgtc ctggtccttt
    10561 aggagcacac atgaagacat ctacatccgc aggaactttg ataaattcaa agtggatgtt
    10621 gaaaccatgg gcaaatccaa ctgcgtttcc agcttccaag cttggagcga tttctgcttc
    10681 gtacaattct tgttgaattt cgtctggcgc caagatcatg ataacatcag ccaacttagt
    10741 agcttctgct actgtgtaag tatcaaatcc atcttctttt gctttatcaa aagatttacc
    10801 tggacgtaca ccgataataa cgtcacgacc tgaatcacgc aagttttgag catgcgcatg
    10861 cccttgtgaa ccataaccga taacggcgat ttttttaccg tcaagtgctg ctactttaac
    10921 atctttttca tattccattt gaactgtcat agcttttctc tcttttctat tatttattgc
    10981 cttttaagct ggtttaacaa atttaagttg gatttttaat cgcgggtaaa tccagttgca
    11041 cccgttcgag caatattgcg aataccgtat gggcgaatga ctcgcaatag ggcttcgctc
    11101 ttttctgcat ttcccgtcat ctgaatggta atcgagcttg gcgctacgtc taccactgtt
    11161 gcacggaaag gttgaataat cgctaaaatc tcagctctct tctcagctgg cgctgacatc
    11221 ttaaccaaaa tcacctcgcg ctccaaatga ggcttgtctg taatatctcg aatgcgaatc
    11281 acatcaatct gacgattgag ctgtttgatg atttgctcca cttcatcatg agaagcaaca
    11341 tcaataataa tagtgatacg cgatacattc ggatcttctg ttgctccaac agagatgctt
    11401 tcaatattaa cctgacgacg agataggaca cctgtaaagc gattgaggac tcctgaacga
    11461 ttttgtagtt ttgctgttaa cattctacgc atggaactgc acccccaaca tctcatgatt
    11521 actcttacca gccggtacca ttggtaacac ctgttcctta cgagaaatat ctacctcaat
    11581 tagcatagga acatcctcag tgatgacttc aaggtcttga gccaaggtct caggattgtc
    11641 aaacttatag tttttaatac cataagcctg cgccatcaat tggaaatcag gaagggtatc
    11701 aaagaccgac tctgatgttc tgccttcata gaaggattcc tgccactggc gaaccattcc
    11761 gagtgaatga ttgttcagca taaccacctt gattggcacc ttgtaaatat tcaaaatagc
    11821 caactcctgg ttggtcattt ggaaaccacc atccccaaca aacaagacta cttccttatc
    11881 tgggttagca attttagcac cgattgctgc tggaattcca aagcccattg ttcccaaacc
    11941 acctgaagtc actaactgac gttcattttg gtagggataa tactgagctg tccacatttg
    12001 gtgttgacca acgtctgtta ccacaatggc atctccattc gtcaattcac caattcgttc
    12061 aataactgct tgcggttgaa ccacacgctc tttcttgtca tacgaacgaa cacgattctt
    12121 gtctttagtg actttctcaa tccacttttc agtattgttg tgaactgttg gttctgctag
    12181 caacatttgc aaggccttct tagcatctcc aactacagga atgtctgcac tgataatctt
    12241 gccaatctca gctgggtcaa tatcaatgtg ggcaacctta gcattcttag cgaaagtctt
    12301 aggattcccc gtcaaacggt catcgaaacg agaaccaata ctaatcataa agtccgcttc
    12361 cgtcatggca atatttgctg cgaatgaccc gtgcatgcct cccattccaa gaaagagtgg
    12421 gtgactcgtt gcaatcgttc cttgtcccaa aagactggtt accactggaa tttgatagcg
    12481 ttctgcaaat tcatttagtt ccgtagcagc ctcagcataa ctaattccac caccagctaa
    12541 caagactggc tttttagcct tggacaattg cttcaagatt ttcttgattt gcatatcatt
    12601 cggctcaaga gtcggctgat aacttggtaa attcacttct ggtgaataaa tgaagtctgt
    12661 ttctaaagca gatatgtctt ttggtaggtc aattacaact ggccctggac ggcctgtagt
    12721 tgcgatatgg acagcttccg taatgatacg cggaatatca gctgtctcac gaacttggta
    12781 attgtactta gtgattggca tggtaattcc tacgatgtct gcctcctgaa aggcatcctt
    12841 cccaatccct gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc tatcgctcat
    12901 agcatccgca atccctgtaa tggcatttgt tgctcctggt ccactagtga cgacggcaac
    12961 acccaacttt ccagttgatt tggcatagcc ttcagcttca tgcaaacaac cttgctcatg
    13021 gcgccctaga atgtggcgaa tgcctttaaa attatatatc gcatcataaa aaggcaaaac
    13081 cgcaccacca ggataaccaa agatggtatc aactcctaaa tcacgaagtg tttccaaaac
    13141 taggtccgac cccgtcttag gagattctaa actgattttc tccattattc ccctttcttt
    13201 cctcttaaaa ataac
//
LOCUS       DAVLZS010000048        12896 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLZS010000048 DAVLZS010000000
VERSION     DAVLZS010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12896
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.048"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            83..946
                     /locus_tag="VYO88_001624"
     CDS             83..946
                     /locus_tag="VYO88_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1719690.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1329..1949
                     /locus_tag="VYO88_001625"
     CDS             1329..1949
                     /locus_tag="VYO88_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719691.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2036..2479
                     /gene="tsaE"
                     /locus_tag="VYO88_001626"
     CDS             2036..2479
                     /gene="tsaE"
                     /locus_tag="VYO88_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1719692.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2469..2987
                     /locus_tag="VYO88_001627"
     CDS             2469..2987
                     /locus_tag="VYO88_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719693.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            2995..4011
                     /locus_tag="VYO88_001628"
     CDS             2995..4011
                     /locus_tag="VYO88_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1719694.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4096..5352
                     /locus_tag="VYO88_001629"
     CDS             4096..5352
                     /locus_tag="VYO88_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1719695.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5407..6573
                     /gene="recA"
                     /locus_tag="VYO88_001630"
     CDS             5407..6573
                     /gene="recA"
                     /locus_tag="VYO88_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1719696.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAA
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            6880..8250
                     /locus_tag="VYO88_001631"
     CDS             6880..8250
                     /locus_tag="VYO88_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1719697.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVATTWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8626..9582
                     /gene="lytA"
                     /locus_tag="VYO88_001632"
     CDS             8626..9582
                     /gene="lytA"
                     /locus_tag="VYO88_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1719698.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            9940..10101
                     /locus_tag="VYO88_001633"
     CDS             9940..10101
                     /locus_tag="VYO88_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1719699.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            10088..10294
                     /locus_tag="VYO88_001634"
     CDS             10088..10294
                     /locus_tag="VYO88_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719700.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            10340..10693
                     /locus_tag="VYO88_001635"
     CDS             10340..10693
                     /locus_tag="VYO88_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719701.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKNKCY"
     gene            10827..11252
                     /locus_tag="VYO88_001636"
     CDS             10827..11252
                     /locus_tag="VYO88_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719702.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            11660..12445
                     /locus_tag="VYO88_001637"
     CDS             11660..12445
                     /locus_tag="VYO88_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719703.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPFVSEFWNDFKNNH
                     DKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAI"
     gene            12435..12896
                     /locus_tag="VYO88_001638"
                     /pseudo
     CDS             12435..12896
                     /locus_tag="VYO88_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4088 a         2056 c         2802 g         3950 t
ORIGIN      
        1 aattatttat tcctttaact tgctattttg aactaaaaat tttataatga aattaagcaa
       61 acaggaaggt ttattatctt taatgaatac actcgcagag aaattcagat tgaaaagaaa
      121 agagttgaga ctctcccagc aaactcttgc agaaggaatt tgtgaacaaa gccagattag
      181 taaaattgag agagggcatt tcattccctc cgcagacctt ttgttcaaac tctctcaacg
      241 acttgaagta ccattagatt atttttttaa tgaacaaatt gaaattaaat ctaacctctc
      301 taatttcaag caattgtctg ctcgactatt agacgataga aattatgacg atttggaata
      361 tatttataga atagagattg aacgaagtac ttttctaaca ctagaagacc gaacttacct
      421 tgaatggatt aaagctatta ttgacttcta tcaatatgac agtaagtgtg aggcaatttc
      481 ttcattggaa aatatattat taaaagtctc ttcaaatact ctgatttatt taaaggcgtt
      541 gaatactcta tctaatttct attccttagt gggtcgtgaa caagaatatg aggcaaacta
      601 ctctcattta atagagttgt atcagacaaa aaatttggac catcaagagt ttttatttgg
      661 ctacatcaga gttcgttaca actacgctca ctacctagta tcaaaggaaa aatataatga
      721 agccatccaa gaagctcttg aaacgattga actctgtaaa caaagacaga caagctacca
      781 attggctcct ctacttattc ttgtaggaaa tgctggagcc aaatttctag acagagaaca
      841 agtcaaaaat tattatatag aagcaagaga gttatgtaag atttataaca atcctttaat
      901 gttgatgaag atagaaaatt atttgaagga actagatact gtttagttaa tcttgacatt
      961 atagtttttc tgaaacgtta aataacctgt aaggctgata gttagattaa tactatcagc
     1021 cttataatta tgtgactctg agtccgtctc gctccgtgag gtgcgagaca aaacaaccac
     1081 ccgtttgacg gattttcatg atttcaaatt tatattcttc gaaaatctct tcaaaccacg
     1141 tcagctctat ctgcaatctc aaaacagtgt tttgagcaac ctgtggctag ctacctagtt
     1201 tgctctttga ttttcattga gtattagtct ctagtgtttg tttagcgtct taaagagaca
     1261 tttgagaaga ttagaaacag ttctctcttt tctcctagta taatgattgg taggaaggga
     1321 gagagaagat gaaatcaatg agaatcttat ttttgttagc tttaattcaa atcagtttga
     1381 gtagctgttt cctatggaag gaatgcatct tgtcctttaa acaaagtaca gcttttttca
     1441 tcggaagcat ggttttcgtt tcaggaatct gtgctggagt aaattatctt tatacccgta
     1501 agcaagaagt ccatagtgtc ctagccagta agaagtcggt gaagcttttt tacagtatgt
     1561 tactcttaat taatttgtta ggagctgttc ttgttttgtc agataacttg ttcatcaaaa
     1621 atacgctgca gcaagaatta gttgactttt tattgccatc cttctttttc ctatttgggc
     1681 tagatttgct gattttttta cccttgaaaa aatacgtgcg cgattttctt gctatgctgg
     1741 acagaaaaaa gacagtgttg gtgactattt tagcaacact tcttttctta agaaatccaa
     1801 tgaccattgt ctcacttctg atttatattg gactgggctt gttttttgca gcctatcttg
     1861 tcccaaattc ggttaagaag gaagtttcct tttatggtca tattttccga gatcttgtat
     1921 tggtcattgt tacgctcatt ttcttttaga gaaagcctgt ttttgtatgg atgttatgat
     1981 gataagttta gtaggaaaat agacacaaaa gaaaagtttt tggtataata agagtatgta
     2041 cacaaaaaat gaagaagagt tgcaagcctt aggggagcgt ttgggccatc tattagcaaa
     2101 gaatgatgtt ttaatcttaa ctggagaact gggtgcaggt aaaacgacct ttactaaagg
     2161 acttgcaaaa ggattacaga tttctcaaat gattaaaagt cccacctata ctatcgtgag
     2221 agagtatgaa ggtcgacttc cactttatca cctagatgtt tatcgtattg aaggagatgc
     2281 tgattctatc gacttggatg agtttatctt tggtggcggc gtgactgtta ttgagtgggg
     2341 aaatctctta ggagatgcct tgccagatgc ttatttagaa ttggaaattc taaaagaagc
     2401 agatggacgc cgtttaaatt ttcaggcaaa gggtttgcgt gctgagaaat tgttagagga
     2461 gcttcaatat ggagtatgaa ttgctcatta gggaagcaga gcccaaagat gcagctgaat
     2521 tagtggcctt tttaaatcgt gtgagtttgg agacagactt taccagccta gacggagatg
     2581 gtattctctt gactagtgag gagatggaaa tattcctcaa caagcaagct agttcggaca
     2641 atcagataac cttacttgca ttcttaaatg gcaaaattgc tggtattgta aatattacag
     2701 ctgatcagcg taagagagtc cgtcatattg gagatctctt cattgtgatt ggaaaaagat
     2761 attggaataa tggcttggga agtttgttgc tagaagaagc gatagagtgg gcacaagcaa
     2821 gtggcattct gcgtcgtctc caactgactg tccaaactcg taatcaagca gcagtccatc
     2881 tttatcaaaa gcatggcttt gtcattgaag gtagccaaga gcgtggggca tatatagaag
     2941 aagggaaatt tatcgatgtt tacttgatgg gtaaactgat aggttagtag aaatatggtt
     3001 aaaaaaatta ttggaatggt gctagcttta ctttctgtaa ctgtagtagg agtaggtgtt
     3061 tttgcttata ctatttatca acaagggaca gaaaccttag ctaaaaccta taaaaaaatc
     3121 ggcgaagaaa ccaaggttat tgaagcgact gaacctctaa ccattctgtt aatgggagtg
     3181 gacaccggaa atgttgaacg aactgaaact tgggtcggta gaagtgatag catgatcttg
     3241 atgacagtga atcctaaaac gaaaaaaaca acaatgatga gtttagagcg ggatattctg
     3301 acgcgcattg aatcagggaa tggtcaggct catgaagcga aactgaactc agcatatgca
     3361 gatggtggag cagagcttgc tatagaaacc attcaaaaaa tgatgaatat ccatattgat
     3421 cgctatgtga tggtcaatat gagagggttg caaaaactag tggatgcagt aggaggtatt
     3481 acagtcaata atatcctagg tttcccaatt tctatcagtg accaagaaga atttaatacc
     3541 atttctatcg gtgttgggga gcaacatatt gggggagaag aagccctagt ctatgcacga
     3601 atgcgttacc aagatcctga gggggattat ggtcgtcaaa aacgtcaacg tgaagttatt
     3661 caaaaagtca tggaaaaagc tctcagttta aatagcattg gtcattatca agagattcta
     3721 aaagctttga gtgacaatat gcagaccaat attgatttgt ctgcaaaaag tatccctaac
     3781 ttgctaggct ataaagattc atttaaaacc attgaaactc agcagttgca gggtgaagga
     3841 gagatacttc aaggtgtttc ttaccagatt gtttcgagag cacatatgtt ggaaatgcaa
     3901 aatatactcc gacgttcttt gggacaagaa gaagttactc agcttgaaac caatgcggtt
     3961 ttatttgaag atttatttgg cagagcacct gttggtgatg aagataatta acttttgata
     4021 caaataaaaa aatcaatcgt aggaaaattc ctgcgatttt ttcaaaaaaa tacgaataga
     4081 taggtaggag gaaacatgaa agcagaaatc attgctgttg gaacagagat tttgacagga
     4141 cagattgtca acaccaatgc ccagtttttg tcggaaaaac tagctgagat tggggtagat
     4201 gtatattttc agacggctgt aggagacaat gaagttcgtc tcttgtcttt gcttgagatt
     4261 gccagtcaac gtagcagtct ggtgattttg acaggcggtt tggggccaac tgaggacgac
     4321 ctaaccaaac aaaccctagc taaattttta gggaaagcat tagtctttga tcctcaggct
     4381 caggagaagt tggatatctt ttttgccctg cgaccagact atgcccgaac accgaataac
     4441 gaaagacaag ctcaaattgt agaaggagcg attccactgc caaacgaaac aggactggct
     4501 gttggaggaa aattagaagt agacggagtg acctatgtcg tccttccagg tccgccaagt
     4561 gaattgaaac ccatggtctt aaaccaactt ctacccaagt tgatgacagg gagcaagctg
     4621 tattcccgag ttcttcgttt ctttgggatt ggcgagagcc agctggttac gattttggct
     4681 gatttaattg ataatcagat cgatcctacc ttggcccctt atgccaagac aggagaagtc
     4741 actctacgtc tgtcaacaaa ggctagcagt caagaagagg cgaatcaagc gctggatatc
     4801 ttggaaaatc aaatcttgga ctgccagact ttcgaaggaa tttctttacg agacttttgc
     4861 tatggttatg gggaagaaac tagtttagcc agcattgtgg tagaagaact gaaaaggcaa
     4921 gggaaaacca tcgcggctgc agagagtttg acggcaggtc ttttccaagc taccgtggcg
     4981 aatttttctg gagtttcaag tatatttaag ggtggttttg tgacctatag cttggaggaa
     5041 aaatcaagga tgttggatat tcctgccaag aatttggaag aacatggtgt ggtgtctgaa
     5101 tttacagctc agaagatggc tgagcaggca cgaagcaaga cccagtctga ttttggaatt
     5161 agtttgactg gagtggcagg accagatagc ctagaaggac acccagttgg gacagtcttc
     5221 ataggcttgg cgcaagatca aggaactgag gttatcaagg ttaatattgg aggcagaagc
     5281 cgagcagatg tacgtcacat tgcggttatg catgccttta acctagttcg caaggcttta
     5341 ttaagtgact aacttttgat ataatagtag ataggtctga ggatcattag aatgtaggag
     5401 aatagaatgg cgaaaaaacc aaaaaaatta gaagaaattt caaaaaaatt tggggcagaa
     5461 cgtgaaaagg ccttgaatga cgctcttaaa ttgattgaga aagactttgg taaaggatca
     5521 atcatgcgtt tgggtgaacg tgcggagcaa aaggtgcaag tgatgagctc aggttcttta
     5581 gctcttgaca ttgcccttgg ctcaggtggt tatcctaagg gacgtatcat cgaaatctat
     5641 ggcccagagt catctggtaa gacaacggtt gcccttcatg cagttgcaca agcgcaaaaa
     5701 gaaggtggga ttgctgcctt tatcgatgcg gaacatgccc ttgatccagc ttatgctgcg
     5761 gcccttggtg tcaatattga cgaattgctc ttgtctcaac cagactcagg agagcaaggt
     5821 cttgagattg cgggaaaatt gattgactca ggtgcagttg atcttgtcgt agtcgactca
     5881 gttgctgccc ttgttcctcg tgcggaaatt gatggagata tcggagatag ccatgttggt
     5941 ttgcaggctc gtatgatgag ccaggccatg cgtaaacttg gcgcctctat caataaaacc
     6001 aaaacaattg ccatttttat caaccaattg cgtgaaaaag ttggagtgat gtttggaaat
     6061 ccagaaacaa caccgggcgg acgtgctttg aaattctatg cttcagtccg cttggatgtt
     6121 cgtggtaata cacaaattaa gggaactggt gatcaaaaag aaaccaatgt cggtaaagaa
     6181 actaagatta aggttgtaaa aaataaggta gctccaccgt ttaaggaagc cgcagttgaa
     6241 attatgtacg gagaaggaat ttctaagact ggtgagcttt tgaagattgc aagcgatttg
     6301 gatattatca aaaaagcagg ggcttggtat tcttacaaag atgaaaaaat tgggcaaggt
     6361 tctgagaatg ctaagaaata cttggcagag cacccagaaa tctttgatga aattgataag
     6421 caagtccgtt ctaaatttgg cttgattgat ggagaagaag tttcagaaca agatactgaa
     6481 aacaaaaaag atgagccaaa gaaagaagaa gcagtgaatg aagaagttac gcttgactta
     6541 ggcgatgaac ttgaaatcga aattgaagaa taagctgtta aagcagtgga gaaatccgct
     6601 actttttcga tttttgattc aagtttttag attatatata gtagcttgaa ataagatatg
     6661 aacaacttta ttaggaaagt caaattaatt tctagaaatg ttttagcagc tacagcgtac
     6721 tattccaaac tcaaccaact ataatagatc gaaactagaa tagtacacat ctacttctaa
     6781 aacattgtta aaaatcgatt tgactgtcct tatttcattc cgctatatat aagtttgctg
     6841 tttcttgtcg ctcctctgga aagctgatat aatagcttta tgaataaaaa acgaacagtg
     6901 gacctgatac atggttcgat tcttccctcg ctcttaagct tcacctttcc aatcttgcta
     6961 tcaaatattt ttcaacagct ctataacact gctgatgtct tgattgttgg acgatttctt
     7021 ggtcaagaat ccttggctgc agtaggagcg acgacagcga tttttgacct gattgtaggt
     7081 tttacacttg gtgttggcaa tggcatgggg attgtcattg ctcgttatta tggggctcgg
     7141 aatttcacta aaatcaagga agcagtagca accacctgga ttttaggtgc tcttttgagc
     7201 attctagtta tgttgctggg ctttcttggc ttgtatcctc tcttgcaata cttagatact
     7261 cctgcagaaa ttcttcctca atcttatcaa tatatttcta tgattgtgac ctgtgtaggt
     7321 gtcagctttg cttataatct ttttgcaggc ttgttgcggt ctattggtga cagtctagca
     7381 gccctgggat ttctgatttt ctctgccttg gttaatgtgg ttctggatct ctattttatt
     7441 acgcaattgc atctgggagt tcaatccgca ggacttgcta ccattatttc gcaaggttta
     7501 tcagcggttc tctgctttta ttatattcgt aaaagtgtgc cagaactctt gccacggttt
     7561 aaacatttca aatgggacaa aagcttgtac gcggatctct tggagcaagg tttggctatg
     7621 ggcttgatga gttcaattgt atctatcggc agtgtgattt tacagttttc tgttaataca
     7681 tttggtgcag tgattattag tgcccagacg gcagctcgac gcattatgac ctttgccctt
     7741 cttcctatga ccgctatttc tgcatcaatg acgacctttg cttctcagaa tctaggagct
     7801 aagcgacctg accgcattgt tcaaggtctt cgaatcggca gtcgtttaag tatatcctgg
     7861 gcagtttttg tttgtatttt cctctttttt gccagtccag ccttggtttc cttcttggct
     7921 agttcgacag atggttactt gatagaaaat ggaagtctct atctgcaaat cagttcagcc
     7981 ttttatccca ttttgagcct cttgttgatt tatcgcaatt gcttgcaggg cttggggcag
     8041 aagatccttc ctctagtttc tagctttatt gaactaatcg gaaaaatcgt ttttgtggtt
     8101 ttgattattc cttgggcagg atataagggt gttatccttt gtgaacctct tatctgggtt
     8161 gccatgacag ttcaactgta cttctcacta ttccgtcatc ccttgataaa agaaggaaag
     8221 gcaattttgg caaccaaagt gcaatcctag ttggatttac tgaataaaat ccatttcctc
     8281 tagtgaaaat cgaaaaaact tgtgttctct tctttagttt ggtgttgaaa atagtttaac
     8341 agacttttga cttcttttat atgatataat aaagtatagt atttatgaaa aggacatata
     8401 gagactgtaa aaatatactt ttgaaaatct ttttagtctg gggtgttatt gtagatagaa
     8461 tgcagacctt gtcagtccta tttacagtgt caaaatagtg cgttttgaag ttctatctac
     8521 aagcctaatc gtgactaaga ttgtcttctt tgtaaggtag aaataaagga gtttctggtt
     8581 ctggattgta aaaaatgagt tgttttaatt gataaggagt agaatatgga aattaatgtg
     8641 agtaaattaa gaacagattt gcctcaagtc ggcgtgcaac catataggca agtacacgca
     8701 cactcaactg ggaatccgca ttcaaccgta cagaatgaag cggattatca ctggcggaaa
     8761 gacccagaat taggtttttt ctcgcacatt gttgggaacg gttgcatcat gcaggtagga
     8821 cctgttgata atggtgcctg ggacgttggg ggcggttgga atgctgagac ctatgcagcg
     8881 gttgaactga ttgaaagcca ttcaaccaaa gaagagttca tgacggacta ccgcctttat
     8941 atcgaactct tacgcaatct agcagatgaa gcaggtttgc cgaaaacgct tgatacaggg
     9001 agtttagctg gaattaaaac gcacgagtat tgcacgaata accaaccaaa caaccactca
     9061 gaccacgttg acccttatcc atatcttgct aaatggggca ttagccgtga gcagtttaag
     9121 catgatattg agaacggctt gacgattgaa acaggctggc agaagaatga cactggctac
     9181 tggtacgtac attcagacgg ctcttatcca aaagacaagt ttgagaaaat caatggcact
     9241 tggtactact ttgacagttc aggctatatg cttgcagacc gctggaggaa gcacacagac
     9301 ggcaactggt actggttcga caactcaggc gaaatggcta caggctggaa gaaaatcgct
     9361 gataagtggt actatttcaa cgaagaaggt gccatgaaga caggctgggt caagtacaag
     9421 gacacttggt actacttaga cgctaaagaa ggcgccatgg tatcaaatgc ctttatccag
     9481 tcagcggacg gaacaggctg gtactacctc aaaccagacg gaacactggc agacaagcca
     9541 gaattcacag tagagccaga tggcttgatt acagtaaaat aataatggaa tgtctttcaa
     9601 atcagaacag cgcatattat taggtcttga aaaagcttaa tagtatgcgt tttcttgtgg
     9661 agatatttcc ttcaattttg ctactatatt aaacaaaaat caaaaagcaa actagaaagt
     9721 tatgctcaaa taaaatctaa atttgacaat gtaaaccgag tcggatagct ttaagtactg
     9781 ttttgaggtt gaagatacga tttttgatag gaactcatca attttagatt tttaagcagc
     9841 atcaataaat tgcttccttg ttttgtcata atttttttat ttaaaaaatt atgacaagag
     9901 tgtgctattc tttttatgag aggtgtatga atatgataaa tgtatgtgat aaatgtatgt
     9961 gatgttggaa aaagaataaa agaacttaga atatcttcaa atcttactca agataagatt
    10021 gctgagtatt tgtctttgaa tcaaagcatg attgccaaaa tggaaaaagg tgaaaggaat
    10081 atcacgaatg gatttaagta ataaagcttc aaatcttaga aaaaagttgg gagctgatgg
    10141 tgaatcgccg atagatattt ttaaattggt acaaaagata gaaaatttga cgctggtatt
    10201 ttatggactc ggaaagaata ttagcggagt ctgttataaa ggaactcagt tcagtctcat
    10261 tgcagtcaat tcagacatgc cattaggaag gtaaagattt tctttagcac atggactgta
    10321 tcatctttat tatgatgagg tgaagaagag ttcagtcagt cttatcttga ttggtgaagg
    10381 agatgaaact gaaagaaaag cggatcagtt tgcttcttat tttttaattt tcccatcttc
    10441 actgtatagg atggttgagg aaatcagaga aaatgccaat agaactcatc ttgaagtaga
    10501 agatattata aaattgggtc agttttatgg tatcagtcat aaagctatgt tatatagatt
    10561 gaggaatgat ggataccttg atgcagaaga aattaaaaat atggatatta gtgttataga
    10621 gacagcttca agattaggct atgatacaag tttatatcgt cctttgtcag aaagtaaaaa
    10681 taaatgttat taggataata tattaataca actgaacaac ttttagaaaa taacagaatt
    10741 tcgcaaggga agtatgagga actgttacta gatgctttca gatatgatat tgtatatggg
    10801 ctagatgaag aggggggagt tgtcgtttga ctagtcgtgt atttattgat gcagattgta
    10861 tttcagtatt tttatgggtt ggcactgaac atcttttaga aaagctctat ttgggtaaaa
    10921 ttgttattcc acaagaggtg tatgatgaaa tcaatatacc tacaattccc catttaaaat
    10981 ctaggataga tcagttggta gctaagggtt cagctgagat tgtgagcata gacattggaa
    11041 ctgaagaata cgcattatat agagatttaa caagaaatca tgatagtaac aagattattg
    11101 gtaagggaga agcgacttct attttcttag cgaaaaagca taatgggata ttaggaagta
    11161 ataacctaag agatgttaaa ccatatgtag aagaattttc tttagaacat atgacaacag
    11221 gagatatact gattgaagcg tttaaagcgt aatttattac tgaacaagag ggcaatcata
    11281 tctggaataa tatgcttaaa aagagaagga aaattggtgc aaattcattt tcagactatc
    11341 ttcgtggaag tattcatcaa aatagacaaa aataaatttg gataaatcga actcactatt
    11401 caggaggcat atgagcaatt cgaaaaagaa aagtgtcaaa ttgagcctat aggagtagaa
    11461 gtgaaatagt aagtcctgca tagtggatga gagaaaagtt ctccttgaag ttttcctgaa
    11521 ctatcagtcg catgtcaaac gatatgtagg gtaatgtgag aggggatagc gagtagtttt
    11581 tggttatttt atcaaaaaac ttatatttta ttataccgaa tgataaaata taataaaaat
    11641 gatagaataa ggaaaaaaca tgaatgtcaa aaagataatg tcaatttttc aatcctttta
    11701 tgttgatgtc agtattgagg aactgacttt gactttacca atcagttttg taaaaaggtt
    11761 tgagtatact caaatgactt ttcataagga atcattttta ttgattaaag aaaagagaag
    11821 ggggagtttg agttcatttg ttactcaggc tcgcactatg ggtgaaaaag ccaatatgga
    11881 tgttgttttg gtgttttcga agttatcaga cagtgaaaaa aagcaattac ttcaagctag
    11941 agttccgttt gtagacttta agggaaacct cttcttccct ccattgggac tagtactcaa
    12001 tgcgaatgat actgaaatcc ctaaggaatt aacacctagc gaacaattaa cgtggattgc
    12061 ctttttattg ccagatggcg atataaagca gataaaatct gtttctaacc ttctatatgg
    12121 tggtgcttat gctttgtcgc attcaacttt tttagctgaa acggatgaaa atactagcta
    12181 tgtcatatgg cagagaaaat tcaatcagtt atccttgcca ctttctcagc atgttttaaa
    12241 aggaaagatg ctagagatat ggaaatatcg tccttttgta tctgagtttt ggaatgattt
    12301 taaaaataat catgataaac aatttgtaga tccgatttct ctttatttga ccttaaaaga
    12361 tgatgatgac ccacgtatag aggaagagag tgaagcacta gaaaatatga tattacagta
    12421 tctgggagaa gatgatgcca tataatacga aagttatttt tcaagaaatg tttgcggatt
    12481 ttcagaacta ttatgttctg attgggggaa ctgctacctc tatcgtattg gattcgcaag
    12541 gatttaaaag tcgcacaaca aaagattatg atatggtcat cattgatgaa gtaaaaaata
    12601 aggaatttta tactaccttg aatcattttt tagaattggg agagtatcaa ggaagtcaga
    12661 aagatgagaa agcgcagctt tttcgattta caacaactaa ttctgagttt ccttctatga
    12721 ttgaactatt tagtatctta ccagaatatc cattaaagaa ggacggtcga gaaattccct
    12781 tatattttga caagatgcta gtttatcagc cttattattg gatgaagatt attataatat
    12841 attggtgcat gtaaaagaaa ccattcaggg gtattcggta ttgagtaatt gtggtc
//
LOCUS       DAVLZS010000049        12059 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLZS010000049 DAVLZS010000000
VERSION     DAVLZS010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12059
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.049"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(99..1730)
                     /locus_tag="VYO88_001639"
     CDS             complement(99..1730)
                     /locus_tag="VYO88_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV1719704.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2023..7002
                     /locus_tag="VYO88_001640"
     CDS             2023..7002
                     /locus_tag="VYO88_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV1719705.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETASPASNEAATTE
                     TAEAASATKPEEKASEVVAETPSVEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQSDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFALSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNTVLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTAPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7092..8288
                     /locus_tag="VYO88_001641"
     CDS             7092..8288
                     /locus_tag="VYO88_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1719706.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8424..8951
                     /locus_tag="VYO88_001642"
     CDS             8424..8951
                     /locus_tag="VYO88_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1719707.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9028..9384
                     /gene="glnR"
                     /locus_tag="VYO88_001643"
     CDS             9028..9384
                     /gene="glnR"
                     /locus_tag="VYO88_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1719708.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9421..10767
                     /gene="glnA"
                     /locus_tag="VYO88_001644"
     CDS             9421..10767
                     /gene="glnA"
                     /locus_tag="VYO88_001644"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1719709.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10857..10976)
                     /locus_tag="VYO88_001645"
     CDS             complement(10857..10976)
                     /locus_tag="VYO88_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1719710.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11466..12059
                     /locus_tag="VYO88_001646"
                     /pseudo
     CDS             11466..12059
                     /locus_tag="VYO88_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3881 a         2207 c         2587 g         3384 t
ORIGIN      
        1 ctatatatct gcagaatact ctttcagttt cattcagcct agtcttgctt aggaaaaagt
       61 aaaaagccat ccaattatga tggatagctt cttggttctt agatttgttc tgcaaaaacc
      121 ttttcagcaa ggttcatagc gtggtctgat acacgagtgt agtgtgagat gatgtcgata
      181 aagttgaccc cagcttgtgt tgaacattcg cctttgttga ggcgtttgat gtgggttttt
      241 ctgagaacac gttctatctt attgattgct tcatgacgtt ctacaagact gcgtgctttt
      301 tcaatatcat tgttttccac actatccaga gcatctttga taaagtcact agtttggcgg
      361 taaacttcct ctaattcttt caaggcggca tcagaaaatt caacattttt ccgttgaaga
      421 tagtcagtca gattgagtag agcctccgtg tggtctccaa tccgttccaa atcacgggag
      481 gaatcaagga tattggtaag cacttcactt tctttttggc tgagagcttc gcttgaaagg
      541 gcaatgagat aacgtgttaa ttgctcatcg atggtgttaa ttgcttcttc ggttttatgc
      601 cctttttcag caactttttc atccaagtca atgatgtact tataggaaag gtcaaaggct
      661 ttagcagcgt agtttcctaa gtgcaagagc tctttcttag catttcctag agcgatagat
      721 ggggcctgtt tgatgaaatg ttcatcaaga tataagggtt cgtatttgac aacctcgtcc
      781 tctccaggaa taatcttggt tacaaagtaa gccagagctc cgataaatgg aaattggaca
      841 atggtgttgg taatattaaa ggttccgtga gcaaaggcga tggtcatttc cggtgctaga
      901 tttagcgtag cttcaaacca atgaatcagg acagtaaaag gaactagaaa aataacgcag
      961 acgactgttc cgataacgtt gaaggcaaca tgagctcctg ctacccgttt agctgcaata
     1021 ttagccccta aagaggcaat gatggctgta atggttgtcc cgatattgtc accaaataga
     1081 accggcaaag ctccctgtag gtcaattaga ttgccggcgt agaggttttg taaaatccca
     1141 atggtagccg aagaagcttg aattagcaag gtcaagccag taccgacaaa gacacccaaa
     1201 acaggatttt tacttagctc aatcatatag tccttaaaga cctgtaaatc cttgagtgga
     1261 gccattgcgc cgctcatgag attgagggca aaaaagatac caccgacacc aaagaggatg
     1321 cgtccgatat tattgactgt ccgatttttt gtaaaaaaga gacagacggc accgataaag
     1381 agcataggta gggcatagtt acctaattta aaaccgatga gaaaggatgt gacagttgtc
     1441 ccaatattag cacccatgac aatcccgata gcctgacgta aggttaagag accggcactg
     1501 accaggccga ctgtgataac tgttacacca gaactagact gaattagagc agtcatccca
     1561 ataccaacca gaactccaaa gaaaggatta ctagtatatt tgtcaatgta aaaacgaagg
     1621 cgatctccag cagcttgttg taaaccgtct cccatggtct tgatgctata taagaatagc
     1681 cccagaccac ctaaaaagtg aaataaaatt tcctgccaat taatggacat ttctttttcc
     1741 tccgaaaaat aatcgcggaa tatctcctat tctattttaa aggataaaag taaatctaac
     1801 aagtgttaat gtcaagtttg taaaagaaaa ttataattga taagtgtatt atttttaaga
     1861 gtttttaacc ttattttaga tttgtgcaaa cagttattgt tttttgtcta aaaatgtttt
     1921 aggataaaaa tgtgattatc atggttctag agtttgataa aaaactacag aatataaagc
     1981 gctttcttga aaacaacaaa atcaatcttt taggaggaga aaatgaagaa tccatttttt
     2041 gaaagacgtt gtcgttacag tattcgtaag ttatcagtag gagcctgctc gctgatgatt
     2101 ggtgctgttt tatttgctgg tccagccttg gctgaagaaa ctgcagttcc tgaaaatagc
     2161 ggagctaata cagagcttgt ttcaggagag agtgagcatt cgaccaatga agctgataag
     2221 cagaatgaag gggaacatgc tagagaaaac aagctagaaa aggcagaagg agtagcgaca
     2281 gcatctgaaa ctgcttcgcc agcaagcaat gaagctgcaa ctactgaaac tgcagaagca
     2341 gctagcgcaa ctaaaccaga ggaaaaagca agtgaggtgg ttgcagaaac accatctgta
     2401 gaagcaaaac ctaagtctga caaggaaaca gaagcaaagc ccgaagcaac taaccaaggg
     2461 gatgagtcta agccagcagc cgaagctaat aagactgaaa aagaagtcca gtcagatgtc
     2521 cctaaaaata cagaaaaaac attaaaacca aaggaaatca aatttaattc ttgggaagaa
     2581 ttgttaaaat gggaaccagg tgctcgtgaa gatgatgcta ttaaccgcgg atctgttgtc
     2641 ctcgcttcac gtcggacagg tcatttagtc aatgaaaaag ctagcaagga agcaaaagtt
     2701 caagccttat caaacaccaa ttctaaagca aaagaccatg cttctgttgg tggagaagag
     2761 ttcaaggcct atgcttttga ctattggcaa tatctagatt caatggtctt ctgggaaggt
     2821 ctcgtaccaa ctcctgacgt tattgatgca ggtcaccgta acggggttcc tgtatacggt
     2881 acactcttct tcaactggtc taatagtatt gcagatcaag aaagatttgc tgaagctttg
     2941 aagcaagacg cagatggtag cttcccaatt gcccgtaaat tggtagacat ggcaaagtat
     3001 tatggctatg atggctattt catcaaccaa gaaacaactg gagatttggt taaacctctt
     3061 ggagaaaaga tgcgccagtt tatgctctat agcaaggaat atgctgctaa ggtaaaccat
     3121 ccaatcaagt attcttggta tgatgccatg acctataact atggacgtta ccatcaagat
     3181 ggtttgggag aatacaacta ccaattcatg caaccagaag gagataaggt tccggcagat
     3241 aacttctttg ctaactttaa ctgggataag gctaaaaatg attacactat tgcaactgcc
     3301 aactggattg gtcgtaatcc ttatgatgta tttgcaggtt tggaattgca acagggtggt
     3361 tcctacaaga caaaggttaa gtggaatgac attttagacg aaaatgggaa attgcgcctt
     3421 tctcttggtt tatttgcccc agataccatt acaagtttag gaaaaactgg tgaagattat
     3481 cataaaaatg aagatatctt ctttacaggt tatcaaggag accccactgg ccaaaaacca
     3541 ggtgacaaag attggtatgg tattgctaac ctagttgcgg accgtacgcc agcggtaggt
     3601 aatactttta ctacttcttt taatacaggt catggtaaaa aatggttcgt agatggtaag
     3661 gtttctaagg attctgagtg gaattatcgt tcagtatcag gtgttcttcc aacatggcgc
     3721 tggtggcaga cttcaacagg ggaaaaactt cgtgcagaat atgattttac agatgcctat
     3781 aatggcggaa attcccttaa attctctggt gatgtagccg gtaagacaga tcaggatgtg
     3841 agactttatt ctactaagtt agaagtaact gagaagacca aacttcgtgt tgcccacaag
     3901 ggaggaaaag gttctaaagt ttatatggca ttctctacaa ctccagacta caaattcgat
     3961 gatgcagatg catggaaaga gctaaccctt tctgacaact ggacaaatga agaatttgct
     4021 ctcagctcac tagcaggtaa aaccatctat gcagtcaaac tattttttga gcatgaaggt
     4081 gctgtaaaag attatcagtt caacctcgga caattaacta tctcggacaa tcaccaagag
     4141 ccacaatcgc cgacaagctt ttctgtagtg aaacaatctc ttaaaaatgc ccaagaagcg
     4201 gaagcagttg tgcaatttaa aggcaacaag gatgcagatt tctatgaagt ttatgaaaaa
     4261 gatggagaca gctggaaatt actaactggc tcatcttcta caactattta tctaccaaaa
     4321 gttagccgct cagcaagtgc tcagggtaca actcaagaac tgaaggttgt agcagtcggt
     4381 aaaaatggag ttcgttcaga agctgcaacc acaacctttg attggggtat gactgtaaaa
     4441 gataccagcc taccaaaacc actagctgaa aatatcgttc caggtgcaac agttattgat
     4501 agtactttcc ctaagactga aggtggagaa ggtattgaag gtatgttgaa cggtaccatt
     4561 actagcttgt cagataaatg gtcttcagct cagttgagtg gtagtgtgga tattcgtttg
     4621 accaagccac gtaccgttgt tagatgggtc atggatcatg caggggctgg tggtgagtct
     4681 gttaacgatg gcttgatgaa caccaaagac tttgaccttt attataaaga tgcagatggt
     4741 gagtggaagc tagctaagga agtccgtggt aacaaagcac acgtgacaga tatcactctt
     4801 gataaaccaa tcactgctca agactggcgc ttgaatgttg tcacttctga caatggaact
     4861 ccatggaagg ctattcgtat ctataactgg aaaatgtatg aaaagcttga tactgagagt
     4921 gtcaatattc cgatggccaa ggctgcagcc cgttctctag gcaataacaa ggtacaagtt
     4981 ggctttgcag atgtaccggc tggagcaact attaccgttt atgataatcc aaattctcaa
     5041 actccgctcg caaccttgaa gagcgaagtt ggaggagacc tagcaagtgc accattggat
     5101 ttgacaaatc aatctggtct tctttattat cgtacccagt tgccaggcaa ggaaattagt
     5161 aatgtcctag cagtttccgt tccaaaagat gacagaagaa tcaagtcagt cagcctagaa
     5221 acaggaccta agaaaacaag ctacgccgaa ggggaggatt tggaccttag aggtggtgtt
     5281 cttcgagttc agtatgaagg aggaactgag gacgaactca ttcgcctaac tcacgcaggt
     5341 gtatcagtat caggttttga tacgcatcat aagggagaac agaatcttac tctccaatat
     5401 ttgggacaac cggtaaatgc taatttgtca gtgactgtca ctggccaaga cgaagcaagt
     5461 ccgaaaacta ttttgggaat tgaagtaagt caggaaccga aaaaagatta cctagttggt
     5521 gatagcttag acttgtctga aggacgcttt gcagtggctt atagcaatga caccatggaa
     5581 gaacattcct ttactgatga gggagttgaa atttctggtt acgatgctca aaagactggt
     5641 cgtcaaacct tgacgcttca ttaccaaggc catgaagtta gctttgatgt tttggtatct
     5701 ccaaaagcag cattgaacga tgagtacctc aaacaaaaat tagcagaagt tgaagctgct
     5761 aagaacaagg tggtctataa ctttgcttca tcagaagtaa aagaagcctt cttgaaagca
     5821 attgaagcgg ccgaacaagt gttgaaagac catgaaacta gcacccaaga tcaagtcaat
     5881 gaccgactta ataaattgac agaagctcat aaagctctga atggtcaaga gaaatttacg
     5941 gaagaaaaga cagagcttga tcgcttaaca ggtgaggttc aagaactctt ggctgccaaa
     6001 ccaaaccatc cttcaggttc tgccctagct ccgcttcttg agaaaaacaa ggccttggtt
     6061 gaaaaagtag atttgagtcc agaagagctt acaacagcga aacagagtct aaaagatctg
     6121 gttgctttat tgaaagaaga caagccagca gtcttttctg atagtaaaac aggtgttgaa
     6181 gtacacttct caaataaaga gaagactgtc atcaagggtt tgaaagtaga gcgtgttcaa
     6241 gcaagtgctg aagagaagaa atactttgct ggagaagatg ctcatgtctt tgaaatagaa
     6301 ggtttggatg aaaaaggtca agatgttgat ctctcttatg cttctattgt gaaaatccca
     6361 attgaaaaag ataagaaagt taagaaagta tttttcttac ctgaaggcaa agaggcagta
     6421 gaattggctt ttgaacaaac ggatagtcat gttatcttta cagcacctca ctttactcat
     6481 tatgcctttg tttatgaatc tgctgaaaaa ccacaacctg ctaaaccagc accacaaaac
     6541 acagtccttc caaaacctac ttatcaaccg acttctgatc aacaaaaggc tcctaaattg
     6601 gaagttcaag aggaaaaggt tgcctttcat cgtcaagagc atgaaaatac tgagatgcta
     6661 gttggggaac aacgagtcat catacaggga cgagatggac tgttaagaca tgtctttgaa
     6721 gttgatgaaa acggtcagcg tcgtcttcgt tcaacagaag tcatccaaga agcgattcca
     6781 gaaattgttg aaattggaac aaaagtaaaa acagcaccag cagtagtagc tacacaggaa
     6841 aaaccagctc aaaatacagc agttaaatca gaagaagcaa gcaaacaatt gccaaataca
     6901 ggaacagctg atgctaatga agccctaata gcaggcttag ccagccttgg tcttgctagt
     6961 ttagccttga ccttgagacg gaaaagagaa gataaagatt aaatatcgaa aaatcttgtg
     7021 aaatctttcc ttatatttcc aaagtgtgat ataatagttt cgaataaaat aaataaagga
     7081 gtttttgtaa catggcaaaa cttactgtta aagacgttga cttgaaaggt aaaaaagtcc
     7141 tcgttcgtgt tgacttcaac gtaccattga aagatggcgt aatcactaac gataaccgta
     7201 tcacagcagc tcttccaact attaagtaca tcatcgaaca aggtggacgt gcaattcttt
     7261 tctctcacct tggacgtgtg aaagaagaag ctgataaagc tggtaaatca cttgctcctg
     7321 tagcagctga cttggcagca aaacttggtc aagatgttgt tttcccaggt gtcactcgtg
     7381 gtgctgaatt ggaagcggca atcaacgctc ttgaagatgg acaagttctc ttggttgaaa
     7441 acactcgtta cgaagatgtt gacggcaaga aagaatctaa aaacgatcct gaacttggta
     7501 aatactgggc atcacttgga gatggtatct tcgtaaacga tgcattcggt acagctcacc
     7561 gtgcacacgc atctaacgtt ggtatctcag caaacgttga aaaagcagtt gctggtttcc
     7621 ttcttgaaaa cgaaattgcc tacatccaag aagcagttga aactccagaa cgtccattcg
     7681 tggctatcct tggtggttca aaagtttcag acaagatcgg tgttatcgaa aacttgcttg
     7741 aaaaagctga taaagtcctt atcggtggtg ggatgactta cacattctac aaagcacaag
     7801 gtatcgaaat cggtaactca cttgtagaag aagacaaatt ggatgttgcg aaagctcttc
     7861 ttgaaaaagc aaatggtaaa ttgatcttgc cagttgactc aaaagaagct aacgcatttg
     7921 ctggttacac tgaagtgcgt gacactgaag gtgaagcagt ttctgaaggc ttccttggtc
     7981 ttgacatcgg tccaaaatct atcgccaaat ttgacgaagc tttgactggt gccaaaacag
     8041 ttgtatggaa cggacctatg ggtgtatttg aaaacccaga tttccaagct ggtacaatcg
     8101 gtgtgatgga cgctatcgtg aaacaaccag gagttaaatc aatcatcggt ggtggtgact
     8161 cagctgccgc agcgattaac cttggccgtg cagacaagtt ctcatggatt agtacgggtg
     8221 gtggagcatc aatggaactt cttgaaggta aggttcttcc aggacttgca gccttgacag
     8281 aaaaataaga ttttataaac aaatcaaaga agagagggat gaaagttcct cttttctttt
     8341 gcttaaaata aaaacgcttc ctctcaacta ttactcataa aaatcaccga tttatgataa
     8401 aatggaaata gaaagttgag attatgagtt attttaaaaa atataaattc gataaatccc
     8461 agttcaaact tggtatgcga acctttaaaa caggtattgc tgtttttcta gttctcttga
     8521 tttttggctt ttttggctgg aaaggtcttc aaattggtgc tttgacagcc gtttttagcc
     8581 tgagggagag ttttgatgag agtgttcatt ttgggacttc gcgtattcta ggaaatagta
     8641 tcggtggact ctatgccttg gtcttcttct tattaaatac ctttttccac gaagcctttt
     8701 gggtgacctt ggtagttgtt ccaatctgca ccatgttaac cattatgaca aatgtagcca
     8761 tgaataacaa agcaggggtt attggtggtg tagcagctat gttaatcatt accctatcaa
     8821 ttccaagtgg tgagacaatt tcgtacgtgt ttgtgcgtgt atcagaaacg tttatgggag
     8881 tttttgtcgc aattatcgta aattacgata ttgatcgtat tcgtctcttt ttagagaaaa
     8941 aagaaaaata atgttacatt ttataacatt atcaattgac gtttgtcttt ttttagacta
     9001 taatagacag aaagaaggaa attgtaaatg aaggaaaaag aatttcgccg aaatatggct
     9061 gtttttccta tcggcagtgt tatgaagttg accgatctat cggcgcgtca gattcgttat
     9121 tatgaagatc aagagttgat caagcccgat cgaaacgaag gaaatcgtcg catgtattcc
     9181 ttgaatgaca tggatcgtct gcttgaaatc aaagattata tctctgaagg ttataatatc
     9241 gctgccatta agaaaaaata tgctgaacgt gaagcgaaat ccaagaaagc ggttagtcag
     9301 actgaagtac gtcgtgcact tcacaatgaa ctcctccaac aggggcgttt tgcttcagta
     9361 cagtcacctt ttggtcgcgg ttaggcaacc gcaagtagtc atagattaag gagaaaactt
     9421 atgccaatca cagctgcaga tattcgtcgt gaagtcaagg aaaaaaatgt tacctttatt
     9481 cgtcttatgt tctcagatat tttgggaacc atgaaaaacg tcgaaattcc tgctacagat
     9541 gaacagttag ataaggtctt gtcgaacaag gttatgtttg atggatcttc tattgaaggt
     9601 tttgtacgta tcaatgagtc ggatatgtac ttgtacccgg acttggatac atggacagtc
     9661 ttcccttggg gagatgaaaa tggaagtgtt gcaggtctga tctgtgatgt ctatacaaca
     9721 gaaggtgaac catttgcggg tgaccctcgt ggtaatttga aacgagctct tcgtcacatg
     9781 gaagaagttg gattcaaatc cttcaacctt ggtccagagc cagaattctt cctatttaag
     9841 ttggatgaaa atggggaccc aacacttgaa gtgaatgaca agggtggcta ctttgatttg
     9901 gcacctactg accttgcgga caacacacgt cgtgagattg tgaatgtctt gaccaaaatg
     9961 ggatttgaag tagaagcgag tcaccacgag gttgcggttg gacagcatga gattgacttt
    10021 aagtacgatg aagttctccg tgcttgtgat aagattcaaa tctttaagct tgttgttaaa
    10081 accattgctc gcaaacacgg actttacgca acatttatgg cgaagccaaa atttggtatt
    10141 gctggatcag gtatgcactg taatatgtcc ttgtttgatg cagaaggaaa taacgccttc
    10201 tttgatccaa atgatccaaa aggaatgcag ttgtcagaaa cagcttacca tttcctaggc
    10261 ggtttgatca agcatgctta caactatact gccatcatga acccaacagt taactcatac
    10321 aaacgtttgg ttccaggtta tgaagcgcct gtttacattg cttgggctgg tcgtaaccgt
    10381 tcgccacttg tgcgcgtacc tgcttcacgt ggtatgggaa ctcgtcttga gttgcgttca
    10441 gtggatccaa tggcgaaccc ttacattgct atggctgttc ttttggaagt tggtttgtat
    10501 ggtattgaaa ataaaatcga agcaccagct cctatcgaag aaaatatcta catcatgaca
    10561 gcagaagagc gcaaggaagc tggtattaca gaccttccat caactcttca caacgctttg
    10621 aaagctttga cagaagatga agtggttaaa gctgctctcg gagatcacat ctacactagc
    10681 ttccttgaag ccaaacgaat cgaatgggca agttatgcaa ccttcgtttc acaatgggaa
    10741 attgataatt atttagacct ttactaatat agaagaaaga ttgcctgtgg gtaaacagtc
    10801 acacagcagt ctaagccatc aaatacctat aacccttaaa atagcgattt cggtcgctat
    10861 ttatttttcg aaaaatcctc ttgactcttt tgcgaattag atttatcatc agacgtgtag
    10921 aagaaaatta aggagtcact atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa
    10981 acaagttact tcaaatcgaa atctacaagt ttactaactt ttgcaagctt caaaattaca
    11041 catctgtaaa tattttttcg aaagatatat ttgaagccat agtaaattga gactagaata
    11101 gtacactaca tctgctaaaa atttctagaa actaatttaa ctttcctaat cgatttgttt
    11161 acatcttatt tcaatctact ataattatct caataaatga tgatggcgac tgttttgttt
    11221 gtgcttgtcg atttttgaat ccctgatcga gcggaagaat atttctgccg aggttgccaa
    11281 ggggaaaata ctgaagatat tgaattttat gatgaacaat tacaggcaga aaaggtggag
    11341 gttttgaata ttcgattgga agtaaaaaat tgaattatct acaatctcat caacaataaa
    11401 cctatttcag ccccattatc tataggcgta tttttacgcc tttttatata cttgaagcac
    11461 ataagaaaca ttatgggaag tttgctgatg gaagtactca agaaattgat gttccttatg
    11521 atattcctga tacttgggag tgggtgagga taaaatcaat ttattggaat tttgggcaaa
    11581 ataagccaga gaaatccttt aggtatatag atacgtctag tattgataga aaaaagaaca
    11641 taatcaacta caaaaatcta caatatcttt cacctgaaca agcgccttcc cgtgctagaa
    11701 aattagtttc gcagaatagt gtcttatttt caacagttag accatatcta aaaaatattg
    11761 ctgtagttag agaacttaaa gagtatttga tagctagtac agcatttatt gttttggata
    11821 ctttacttaa cgaaacatat ttgaaatatt atttattatc agataatttt atcaatcgtg
    11881 ttaataataa atctactgga acaagttatc ctgcaatcaa tgattataat tttaatctat
    11941 tattaattgc tctcccccca ctatccgaac aacaacgaat agtagaagca atcgaatcag
    12001 ctttagaaaa agtagatgaa tatgctgaaa gttataatag actagaacag ctagataaa
//
LOCUS       DAVLZS010000050        11986 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLZS010000050 DAVLZS010000000
VERSION     DAVLZS010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11986
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.050"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            643..1320
                     /locus_tag="VYO88_001647"
     CDS             643..1320
                     /locus_tag="VYO88_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1719711.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFTLGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            1307..2104
                     /locus_tag="VYO88_001648"
     CDS             1307..2104
                     /locus_tag="VYO88_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1719712.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSCGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            2121..3224
                     /locus_tag="VYO88_001649"
     CDS             2121..3224
                     /locus_tag="VYO88_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1719713.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEVSHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            3231..3467
                     /locus_tag="VYO88_001650"
     CDS             3231..3467
                     /locus_tag="VYO88_001650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719714.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     SKHCFEVVDRTDEVSNHTHGKATLTWFELDFRRV"
     gene            3570..4589
                     /gene="galE"
                     /locus_tag="VYO88_001651"
     CDS             3570..4589
                     /gene="galE"
                     /locus_tag="VYO88_001651"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1719715.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            4591..5556
                     /locus_tag="VYO88_001652"
     CDS             4591..5556
                     /locus_tag="VYO88_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1719716.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(5607..5813)
                     /locus_tag="VYO88_001653"
     CDS             complement(5607..5813)
                     /locus_tag="VYO88_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1719717.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            5865..6341
                     /locus_tag="VYO88_001654"
     CDS             5865..6341
                     /locus_tag="VYO88_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1719718.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSHPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            6350..7021
                     /locus_tag="VYO88_001655"
     CDS             6350..7021
                     /locus_tag="VYO88_001655"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1719719.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            7152..7490
                     /locus_tag="VYO88_001656"
     CDS             7152..7490
                     /locus_tag="VYO88_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1719720.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            7493..8122
                     /locus_tag="VYO88_001657"
     CDS             7493..8122
                     /locus_tag="VYO88_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1719721.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            8362..9513
                     /locus_tag="VYO88_001658"
     CDS             8362..9513
                     /locus_tag="VYO88_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1719722.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            9831..10580
                     /gene="truA"
                     /locus_tag="VYO88_001659"
     CDS             9831..10580
                     /gene="truA"
                     /locus_tag="VYO88_001659"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1719723.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            10570..11343
                     /locus_tag="VYO88_001660"
     CDS             10570..11343
                     /locus_tag="VYO88_001660"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1719724.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKSVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            11321..11782
                     /locus_tag="VYO88_001661"
     CDS             11321..11782
                     /locus_tag="VYO88_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1719725.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         3425 a         2241 c         2725 g         3595 t
ORIGIN      
        1 caggcacctt atctgataaa taatagtaat tccaaatatc accctgttgg aaatttttat
       61 cacattttaa acattctttc tctaataaat ccataacaaa ctcctaatta ttaaaatagg
      121 ctagagacac agcactagcc tattccgtaa gtaaagctac ttattttata taaaatataa
      181 ctagcgacct gtaattaaac aagtaaaaga acaatactta gggagacctg tgacaatgat
      241 atcttcctct ggaagtagtt ctaattcaaa caatgtttgt tccatgactg tatcctcctg
      301 ttatgataaa ttccagaaag catagagcaa attcgtggtt cgtctgacta aatttcttat
      361 ctgaacacca ccttcaaata caaattttag tcaaactttt attttttcta actttctaat
      421 tatattctac catgtgtttt tatatgccaa gaattttctg aataaactgt ttatttttta
      481 ttttttgaca tttttgcaaa ttgtttaaaa tctttcaatt ggattcactt attgctttag
      541 gacattgaaa cttctttcgc cagaggtgct tatattactg ggaagttgaa gattgaaatg
      601 tggtataata agaggtaata gagttttgga aagtgagaga agatgatttc aaagagatta
      661 gaattggtag cttcctttgt gtcacagggg gctattttac tagatgtggg aagtgaccat
      721 gcttatctgc ctatcgagtt ggttgagaga ggccaaatca aaagcgctat tgcaggtgag
      781 gtggtggaag gtccctatca gtctgcggtt aaaaatgttg aggctcacgg cctaaaggag
      841 aaaatccaag tccgtttagc caatggcttg gcagcttttg aagagactga ccaagtgtct
      901 gtcattacca ttgctggcat gggtggtcgt ttgattgcta ggattttaga agaaggtttg
      961 gggaagttag ctaatgtaga gcgtttgatc ctccagccca ataatcgtga agacgacttg
     1021 cgtatctggc tacaggatca tggattccag attgtagcag aaagcatctt agaagaagct
     1081 ggaaagtttt atgagatttt ggtggtggaa gcaggacaaa tgaagctatc agccagtgat
     1141 gttcgctttg gtcccttctt gtccaaagaa gtcagtccag tatttgtcca aaaatggcaa
     1201 aaagaagctg agaagctaga gttcaccctc ggacaaatcc cagaaaaaaa tctggaagaa
     1261 cgtcaagttc tagtagataa gattcaagct atcaaggagg tgctccatgt tagcaagtga
     1321 agtgatccaa gcttatgaag ccttttgccc tcaggaattt tctatggagg gagacagctg
     1381 tggtctgcaa attggcactt tagacaaggg tatccaaagg gtcatggtgg ctctcgatat
     1441 tcgtgaagag acggtggctg aagccattga aaagggtgta gacttgatta tcgtcaagca
     1501 cgcgcctatc tttcgtccta tcaaggactt gcttgccagc cgtccgcaaa atcagattta
     1561 catcgacctg attaagcatg acatcgcagt ttatgtcagc cataccaata ttgatatcgt
     1621 tgaaaatggg ctcaatgact ggttttgtca gatgctagga atcgaggaga cgacttatct
     1681 gcaggaaaca ggtccagaac gtggaattgg acgtattggg aatattcagc ctcagacatt
     1741 ttgggaattg gcccaacagg tcaagcaagt ctttgaccta gatagccttc gaatggtgca
     1801 ttatcaagag gatgatttgc agaagcctat ttcaagagta gcaatttgtg gtggaagcgg
     1861 gcagtctttc tataaggatg ctttggcaaa gggggcagat gtctatatca ctggtgatat
     1921 ctactaccat actgctcagg atatgctgtc tgatggcttg ttagcattgg atccaggtca
     1981 ctatatcgaa gtgctttttg tggaaaaaat cgcaacactc cttactcaat ggaaagagaa
     2041 aaaaggctgg gaactagaga ttttacctag tcaagcatcg accaatcctt tccgtcatat
     2101 ctagttagaa agtgaagaca atgaaaaaag ttgccattat tggagcagga attgtgggag
     2161 caacagctgc ctactacctc tcgagagaaa gtgacctaga ggtgaccgtt tttgaccatg
     2221 agcaaggtca agccaccaag gccgcagcag gaattatcag tccttggttt tccaaacgcc
     2281 gtaataaagc ctggtacaag atggcgcgct tgggggctga tttttatgtg gatttattag
     2341 ctgatttaga gaaatcagga caagaaatcg acttttacca gcgttcggga gtctttctct
     2401 tgaaaaagga tgaatccaat ttggaagaac tttatcaact ggccctccag cgcagagaag
     2461 aatctccctt gatagggcaa ttagccattc tgaaccaagc ctcagctaat gaattattcc
     2521 ctggtttgca gggatttgac cgcctgctct atgcttctgg tggagcgaga gtagatggcc
     2581 aacttttagt gactcgtttg ctggaagtca gtcatgtcaa gctggtcaaa gaaaaagtga
     2641 ctctgacacc gttagcatca ggctaccaga ttggtgaaga ggagtttgag caggttattt
     2701 tggcgacggg agcttggttg ggggacatgt tagagccttt aggttatgaa gtggatgtcc
     2761 gtcctcaaaa aggacaacta cgagattatc agcttgccca agacatggaa gattaccctg
     2821 ttgtcatgcc agaaggggag tgggatttga ttccctttgc aggtgggaaa ttatccttag
     2881 gcgctaccca cgaaaatgac atgggatttg atttgacggt agatgaaacc ttgctccaac
     2941 aaatggagga ggccaccttg actcactatc tgattttggc tgaagctact tcaaaatctg
     3001 agcgtgttgg aatccgtgcc tacaccagtg atttctctcc tttctttggg caggtgcctg
     3061 acttaactgg tgtctatgca gccagtggac taggttcatc aggcctcaca actggtccta
     3121 ttattggtta ccatttagct caactgatcc aagacaagga gttgaccttg gaccctgaaa
     3181 attacccaat tgaaaactat gtcaaacgag taaaaagcga ataatactca atgaaaatca
     3241 aagaacaaac taggaaacta gccgcgggtt actcaaagca ctgttttgag gttgtggata
     3301 gaactgacga agtcagctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca
     3361 gctcaaaaca ctgttttgag gttgtagata gaactgacga agtcagtaac catacccatg
     3421 gcaaggcgac gttgacgtgg tttgaattgg attttcgaag agtataagca ttttactgaa
     3481 attttatcag gtagtttagg atggcaaatg acattccctg tcaaaaatgg taaaataaga
     3541 aaaaataatc tgagaatcga ggaaaaaaga tgcaagaaaa gattttggta actggtggtg
     3601 ccggttttat tggaacccac actgttattg aattgatcca agcaggccat caagttgttg
     3661 tggtggataa tcttgtcaat agcaatcgta agagtttaga agttgttgaa agaatcacag
     3721 gagttgagat tcctttctat gaggcagata ttcgtgacac agataccctc agagatattt
     3781 tcaagcagga agaaccgact ggtgtcattc actttgctgg tttgaaggct gttggcgaat
     3841 caacacgtat ccctcttgcc tactatgaca acaatatcgc tggaactgtc agccttttga
     3901 aagccatgga agaaaacaac tgtaaaaaca tcatcttcag ttcttctgcg acagtttacg
     3961 gggatccgca cacagtgccc atcttggaag atttcccact ttcagtgacc aacccatacg
     4021 gtcgtactaa gctcatgcta gaggaaattt tgactgatat ttacaaagca gactcagaat
     4081 ggaatgttgt cttgcttcgt tactttaacc caatcggagc ccatgagagt ggtgatttgg
     4141 gagaaaatcc aaacggtatt ccaaacaatc tcttgccata tgtgactcaa gtagccgttg
     4201 gaaaattaga gcaagtgcaa gtgtttggag acgattacga tacggaagat ggaacaggtg
     4261 ttcgtgacta tatccacgtt gtcgatttgg ctaagggtca cgttgcagct ttgaaaaaaa
     4321 tccaaaaagg ttcaggacta aacgtttata accttggaac tggtaaaggt tactcagttc
     4381 ttgaaattat ccaaaacatg gaaaaagcgg tgggacgtcc tattccttac cgcatcgtag
     4441 aacgtcgccc aggtgatatc gctgcctgct actcagaccc agcaaaagct aaagcagaac
     4501 tcggttggga agcagaactc gacatcaccc aaatgtgtga agacgcatgg cgttggcaaa
     4561 gcaagcatcc aaatggattt gaagactaag atgatgattt caatcatcgt cccttgttta
     4621 aacgaagagg aagtacttcc tcttttttat caggctctgg aagctttact tccagatttg
     4681 gaaacagaaa tcgagtatgt ctttgtcgat gatggatcaa gtgatgggac cttggaactc
     4741 ttaaaggcct atcgggagca aaatccggca gtccattata tttctttctc tcgaaatttt
     4801 ggcaaagaag cagcccttta tgcaggcttg caatatgcga caggagattt ggtggtggtg
     4861 atggatgcag acctccaaga tcctcctagt atgttgtttg agatgaaaaa tgtactagac
     4921 aaaaatgtag acttggactg cgttgggaca cggagaacta gtcgggaggg agaacccttc
     4981 tttcgcagtt tctgtgctgt tctcttttat cgcctcatgc aaaaaatcag cccagtagct
     5041 ctgccgtcgg gtgtccgtga ttttcgtatg atgagaaggt ctgtagtcga tgccatttta
     5101 agcttgaccg agtccaatcg tttttcaaag gggctcttcg cctgggtggg tttcaaaacc
     5161 tactatttgg actatccaaa tgtcgaaagg caggctggca agacaagttg gagttttagg
     5221 caactctttt tctactccat tgaagggatt attaattttt cagattttcc cttgattata
     5281 gcctttgtag ctggtctcct atcttgtttt ctttctctgc tgatgacctt ttttgttgtg
     5341 gttcggaccc tcattttggg caatccgaca tctggttgga cctctctgat ggctgttatt
     5401 ctctttcttg gaggcattca actcttgacc attgggattc tcggcaagta tatcagtaag
     5461 atttatttag agactaaaaa aagaccactt tatcttatca aagaaaaaag tgaccttcct
     5521 gattttacag aaaaaaataa agtgaaaaga ctataatttt acatggaaat gtgctaaact
     5581 agagggagtg gattatcgcc attgatttag gcttcctggt ttccaatcag ggcgcgagtt
     5641 gggcaatttt taacagcctc taagacatcc tgactaggag aaatttcttt ttccagttgg
     5701 tcagggtcat cgtaaaaacg cacgattcca ttatcgtggt aatcaaataa atcagaataa
     5761 gtttggcaaa gcccacaggc gatacatcgt tcaggtataa gtgtgatttt catgttcata
     5821 tttatattgt aataagaaaa gtaaaaaaaa acaaggagta aggtatggca aaagaaccgt
     5881 ggcaagaaga tatctatgat caagaagaat caagagcaga gcgtcggcat cgaaaccacg
     5941 gaggggctga taggatggct aatcgtattt tgacgatcct agctagtatt ttctttgtaa
     6001 ttgtggtggt gatggtcatc gttctcatct atctatcatc ggggggaagt aatcgcacag
     6061 cagccttaaa agactttcat gattctgatg caagtgtagt acaaatctca tcttcaagca
     6121 gttctcatcc tgagcagagt tcagagccag aatctacttc tagtagttca gaagaagctg
     6181 ctaatcctga aggaacgatt aaagttctcg caggagaagg ggaagcagct attgccgctc
     6241 gtgcaggaat ctccattgct cagttagagg ccttgaatcc tgggcacatg gctacaggat
     6301 cttggtttgc taatccaggt gatgttataa aaataaaata ggagccgata tgaaaacaat
     6361 tcaaattgct attgatggtc ctgcttccag cggtaagagt acggtcgcaa agattattgc
     6421 taaggatttt ggattcacct accttgatac aggagctatg tatcgtgcag cgacctatat
     6481 ggctcttaag aaccaattag gagttgaaga agtcgaagct cttctagcct tgttggacca
     6541 gcatccaatc agctttggac gttcagaaac tggagaccag cttgtttttg taggagatgt
     6601 ggatattacc catcctatcc gtgaaaatga agtgaccaat catgtttctg ctattgcagc
     6661 aattcctgaa gtgcgtgaga aactggtttc tctccaacaa gaaattgccc agcaaggcgg
     6721 gattgtcatg gatggtcgcg atattggaac tgttgtattg ccgcaagcag aattgaaaat
     6781 tttcctagta gcttctgttg atgagagagc agagcgtcgt tacaaggaaa atattgccaa
     6841 gggaattgaa acagaccttg aaaccctaaa aaaggaaatt gctgcgcgtg actacaagga
     6901 tagtcatcgt gagacttctc ctctcaaaca agcagaggat gctgtctacc ttgatacaac
     6961 tggtttgaac attcaagaag tagttgaaaa aatcaaagca gaagctgaaa aaagaatgta
     7021 aatgtagaaa agccgataga ttgatatcgg tttttttcta aatttgtcaa aatgctgatt
     7081 ttagggtata atagttgctg ttcgagaaat tttgattttc aaagaatagt gaatgatgat
     7141 aaggagaaac catgaacaat ttaccaaatt gtccaaaatg taactcagag tatgtctacg
     7201 aagacggtgc cctactggtt tgcccagagt gtgctcatga gtggaatcct gctgaagttg
     7261 cagaagtaga agaaggtctt gtcgctatcg atgccaacgg aaataaattg actgatggtg
     7321 atacagtaac tctcatcaag gacttgaaag taaaaggtgc gccaaaagat ttgaaacaag
     7381 ggacgcgcgt gaaaaatatc cgcatcgtag aaggcgacca caatatcgac tgtaagattg
     7441 atggttttgg tgccatgaaa cttaaatcag agtttgtgag gaagatttaa gcatgtcaaa
     7501 acactataaa cttgtatttt atagccgtat cttcttgttt ctagcggctt ttacgggagt
     7561 ttatcttgaa attactaggc atggtggttt tgggatgctt ctctattaca cggttctgtc
     7621 caacctcttg gtaactattt ttacccttta tcttctaaag gttatgagcc gtgtaggtga
     7681 aaattggcaa aggccaagtc tcttgcgctt aaaaggtggg gtcaccatga gtatcatgat
     7741 tacctgtgtg atttaccatt tcctcttggc gcccattgcg actaatttct ataccctaga
     7801 aaatttcctt tgccactata tcgttcccat ctggttttta gcggataccc tcttttttga
     7861 caaacagggt caatacaaga tttgggatcc agcagtgtgg accattttac cctttctgta
     7921 tatgatgttt gctcttttta atggcttggt tctaaaactc aatattccaa atgccaagga
     7981 taatcctttc ccttacttct ttttgaatgt gaacaagggt tggaatgttg tgtttaagtg
     8041 gtgtctgatt atctttgttg cctatatggt agcaggattt attttctact ttatcaagca
     8101 aatcaagaga aagtcatcct aatactcttc gaaaatctct tcaaaccacg tcagtttcca
     8161 tctgcaacct caaaacactg ttttgagcag cctgcggcta gcttcctagt ttgctctttg
     8221 attttcattg agtataagat acaagggatt cattttcgaa tttaagaagg agtctacaaa
     8281 ccaatgaggc ttcttctttt cttgcttatt tgataactat caaaaaagta gaagattaag
     8341 agaaatatag aaagagattt catgaaacaa tttttagaac gggccagcat tttggctctc
     8401 tccctcgttt tgattacctc cttttccatt tcgagtgccc taccagccat gtttgactat
     8461 tatcagggtt attctaagga acaaattgag ctcttggtga gcttgccttc ctttggaatc
     8521 atgatgatgt tactgctaaa tggtttctta gaaaaaatat ttcctgagcg cttacagatt
     8581 agtttgggct tgctgatttt atcattgagc ggtacagctc ccttctggta ccaagcctat
     8641 ccctttgtct ttggaacacg gcttctcttt ggtttgggtc ttgggatgat caatgccaag
     8701 gccatttcta ttatcagtga acgctaccaa ggaaaaaggc gaattcagat gttagggcta
     8761 cgcgcttctg cagaggtcgt tggagcttct ctcattacct tggccgtcgg tcagttgttg
     8821 gcctttggtt ggacagctat ctttctagcc tatagtgctg gatttttggt gctgcccctt
     8881 tatctgctct ttgtccctta tggaaaatca aagaaagaag tcaagaaaag agcgaaggaa
     8941 gcaagtcgtt taactcgaga aatgaaaggc ttgattttta ccttagctat cgaagcggca
     9001 gttgtagttt gtaccaatac agctattacc atccgtattc caagtttgat ggtggaaaga
     9061 ggattggggg atgcccagtt atctagtttt gttcttagta tcatgcagtt gatcgggatt
     9121 gtggctgggg tgagtttttc tttcttgatt tctatcttta aagagaaact gctcctctgg
     9181 tctggtatta cctttggctt ggggcaaatc gtgattgcct tgtcttcatc cttgtgggtg
     9241 gtagtagcag gaagtgttct ggctggattt gcctatagtg tagtcttgac gacggtcttt
     9301 caacttgtct ctgaacgaat tccagctaaa ctcctcaatc aagcaacttc atttgctgta
     9361 ttaggctgta gtttcggagc ctttacgacc ccattcgttc taggtgcaat tggcttacta
     9421 actcacaatg ggatgttggt ctttagtatc ttaggaggtt ggttgattgt aatctctatc
     9481 tttgtcatgt acctacttca gaagagagct taggattgat tcctaagttt ttcttttgat
     9541 actcaatgaa aatcaaagag caaactatag ttgattgagt ttggaatagt acgctgtagc
     9601 tgctaaaata tttctagaaa ttaatttgac tttcctaata gagttgttca tatcttattt
     9661 caatctacta tagaaagcta gccgcaggtt gctcaaaata gtgttttgag gttgcagatg
     9721 gaaactgacg tggtttgaag agattttcga agagtatgag atttttatac ccatacaata
     9781 tttgttttag gtccttgttt acagactaat ttcttgataa aatagaggct atgacgagat
     9841 ataaagcaac tatttcctat gatggttatg cctttgctgg ctttcagcgc cagcctcatg
     9901 cgcgtagcgt tcaggaagaa attgaaaaaa ccttgaccag attaaataaa gggcaaacca
     9961 ttactgttca cggtgctggt aggacagata gtggggttca tgccctggga caggtcattc
    10021 attttgacct gccttatcag atggatgagg agaaactccg ttttgccttg gatacccagt
    10081 ctcctgaaga tattgatgtg atttcgattg agcttgtggc agatgatttt cattgccgtt
    10141 atgccaagca tagcaagacc tatgagttta ttgtggatag aggacgtccc aaaaatccga
    10201 tgcgccgtca ctatgccacc cactttccct acccactcga tgtggaacga atgcagattg
    10261 caatcaaaaa gctagaggga acccatgatt ttaccggttt tacagcctct gggactagtg
    10321 tagaggataa ggttcgcacc atcacagaag ctagtttaat agtcgatgag acaggacaat
    10381 ttttgacctt taccttttca ggaaatggtt tcttgtataa acagattcgc aatatggtgg
    10441 ggactcttct caaaatcggt aacaaccgca tgccagtaga gcagattgat ctcatcttgg
    10501 agaagaagga caggcaactt gcaggtccca ctgcagcacc aaatggtttg tatttaaagg
    10561 agattcgtta tgaagaataa tcgtatttta gcactttctg gaaatgatat ttttagtggt
    10621 ggtggactgt cagctgattt ggctacctat accttgaacg gcttgcatgg gtttgtagca
    10681 gtgacttgtt tgacagcctt gacagaaaaa ggatttgaag tctttccaac tgatgatacc
    10741 atttttcaac atgaattaga tagcttgcgt gatgtggaat ttgggggaat taagattggt
    10801 cttctcccta ctgtcagtgt ggctgagaag gccttggact ttatcaaaca acgcccagga
    10861 gtacctgtgg tgttggatcc tgtcttggtc tgcaaggaaa cgcatgatgt agctgtcagt
    10921 gagctctgcc aagagttgat tcgctttttc ccttatgtta gtgtgattac gcctaatctc
    10981 ccagaagcag aattattatc cggtcaggaa attaaaacct tggaagacat gaaaactgca
    11041 gcgcagaaat tgcatgattt aggagcgcca gcagtcatta tcaagggagg caatcgtctt
    11101 agtcaggaca agtctgtgga tgtcttttat gatggacaga cctttactat cctagaaaat
    11161 ccagttatcc aaggccaaaa tgctggtgca ggttgtacct ttgcctctag cattgccagt
    11221 cacttgatta aaggtgataa acttttgcca gcagtagaaa gctctaaggc tttcgtttat
    11281 cgtgctattg cacaagcaga tcagtatgga gtaagacaat atgaagcaaa caaaaacaac
    11341 taaaatcgcc cttgtatccc tattaaccgc cctttctgtg gttctaggtt atttcttaaa
    11401 aatcccaaca cctacaggaa ttctaactct tttagatgct ggtgtcttct ttgcggcctt
    11461 ttactttggt agtcgtgaag gagcggtagt cggaggacta gcaagtttct tgcttgacct
    11521 cttatcaggc taccctcagt ggatgttctt tagcttggtc aaccatggct tgcagggatt
    11581 tttcgcagga tttaaaggaa aaagtcagtg gttgggcctt attttagcaa ctattgccat
    11641 ggtagggggt tacgccttgg gttctacttt gatgaatggc tgggcagcag ccctcccaga
    11701 aattctacca aattttatgc aaaatatggt agggatgatt gtaggattta ttcttagtca
    11761 aagtatcaag aagattaagt aatactcttc gaaaatctct tcaaaccacg tcagtttcca
    11821 tctgcaacct caaaacactg ttttgagcag cctgaggcta gctttctagt ctgattttca
    11881 ttgaatataa agaggttgag taaaaagtct ttcaaataag aaaaatgaac tgccccccaa
    11941 aagttagaca gaaaaaatct aacttttggg gtgttttatt atgaaa
//
LOCUS       DAVLZS010000051        11979 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLZS010000051 DAVLZS010000000
VERSION     DAVLZS010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11979
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.051"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..135)
                     /locus_tag="VYO88_001662"
     CDS             complement(<1..135)
                     /locus_tag="VYO88_001662"
                     /inference="COORDINATES: protein motif:HMM:NF019884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEV1719726.1"
                     /translation="MDDLFTYRRGDTIERQYKILKILSKHGGPISSRRLSDYLQVSRR
                     T"
     gene            421..1331
                     /locus_tag="VYO88_001663"
                     /pseudo
     CDS             421..1331
                     /locus_tag="VYO88_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019783158.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            1383..1681
                     /locus_tag="VYO88_001664"
                     /pseudo
     CDS             1383..1681
                     /locus_tag="VYO88_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737957.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            1748..3004
                     /locus_tag="VYO88_001665"
     CDS             1748..3004
                     /locus_tag="VYO88_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1719727.1"
                     /translation="MTYTHLTTELIGIKDKNIKILFVLKHQTHLEIRAKLDYDSPRCP
                     HCQGKCIKYDFQKLSKIPILDCQGFPTCLLLKKRRFQCKSCKKVTVAETALVKKNCQI
                     SQPIWEKVTQLHTENMTNIAIARRLHISVSVVQRKLAQFQFEHDFTKLPKVLSWDEFS
                     RNKGKLAFIAQDFETRRIVTILENNRQTTIKNYFYKYPRAVRETVEVVTVDMSGSYIP
                     IIKQLFPRAKIVLDRFHIIQHLSRAMMTTRINIMKTFDKRSLPYRSMKNHRRILQKDS
                     RKLSLNRFFSRTFGQTVTPREVVQKTLNFSDELKFYYELYQILLFHFQEMNSKYFFEL
                     LEDKLDLVNLAFKTVFKTFLKYKTYITNAMELPYSNAKLEATNKLIKDIKRQAFGFRN
                     FTNFKTKIYISLNIKNERTNFVLSRC"
     gene            3063..3764
                     /locus_tag="VYO88_001666"
                     /pseudo
     CDS             3063..3764
                     /locus_tag="VYO88_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            3776..4642
                     /locus_tag="VYO88_001667"
                     /pseudo
     CDS             3776..4642
                     /locus_tag="VYO88_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(4722..5369)
                     /locus_tag="VYO88_001668"
     CDS             complement(4722..5369)
                     /locus_tag="VYO88_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719728.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(5366..6064)
                     /locus_tag="VYO88_001669"
     CDS             complement(5366..6064)
                     /locus_tag="VYO88_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719729.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAIVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(6074..6826)
                     /locus_tag="VYO88_001670"
     CDS             complement(6074..6826)
                     /locus_tag="VYO88_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719730.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(6826..7590)
                     /locus_tag="VYO88_001671"
     CDS             complement(6826..7590)
                     /locus_tag="VYO88_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719731.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(7686..8089)
                     /locus_tag="VYO88_001672"
                     /pseudo
     CDS             complement(7686..8089)
                     /locus_tag="VYO88_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8269..8901)
                     /locus_tag="VYO88_001673"
     CDS             complement(8269..8901)
                     /locus_tag="VYO88_001673"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1719732.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADADVKLVTLSNYSELIHLAQEEGYITPEGLNLLKRFKEDQENWQEG"
     gene            complement(8935..9636)
                     /gene="pyrF"
                     /locus_tag="VYO88_001674"
     CDS             complement(8935..9636)
                     /gene="pyrF"
                     /locus_tag="VYO88_001674"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1719733.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQISLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            9957..10049
                     /locus_tag="VYO88_001675"
                     /pseudo
     CDS             9957..10049
                     /locus_tag="VYO88_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10371..11084)
                     /locus_tag="VYO88_001676"
     CDS             complement(10371..11084)
                     /locus_tag="VYO88_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1719734.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(11077..11916)
                     /locus_tag="VYO88_001677"
                     /pseudo
     CDS             complement(11077..11916)
                     /locus_tag="VYO88_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
BASE COUNT         4045 a         2422 c         1955 g         3557 t
ORIGIN      
        1 cgttctccta gatacttgta aatagtcact caaccttcta gatgaaattg gtccaccgtg
       61 cttagataga atttttaata tcttatattg tctttcgatt gtatcacccc tcctataagt
      121 aaataaatca tctatttgac ctaattatat aatatgtgaa aataatcgtc aattacattt
      181 atttcaacat ttattgttaa catttattga aattattgca aatattataa ttcaagccct
      241 gatatatcaa tatcaacatt tcatttacac catctaaaaa accatctaat aatggctata
      301 ataacaataa actacacttt taattaaatt attaactacc cgttgtgcta gttaattcta
      361 gccaaataaa aaaactttgc gtatcataaa ctcaaaacaa ccacgaaatg agggaatgat
      421 gtgcaaagcc aacattatta tctcgcaaat cccaatcaaa cacaagttat tttttcaaaa
      481 atcttgactc aagttatcgc tttatatgag cgatttgttc cccatgaggt tcgaaatcgg
      541 cgaaatatcc acctacaaaa acagtctgat gtcgttgtta tcgctagtta tctttgggca
      601 attcaagagg gctgcaggac gcaagtgcta tttaccgtgc gattcgtcat aatctcttcc
      661 ctgacaactt ccctgaacgc tcacgatttt gccgtatctg tcaaaatctt gctcaaagta
      721 ttcagcgtat gcgctatttt atggtcttag atctttgtca aacctgctcg ttcggcttga
      781 ttgacagctt tccttgtgcc ctatgtcacc ccattcgcaa catgagagct acattgttat
      841 cagaggtggc agatattggc tataatgcga ctaagaaaat ccattattat ggcttgaaat
      901 tttcagttct tgtcagcgac agtgggtttc ctattgatta tgttgtcaca cccgcatcta
      961 tttatgatgg cgatgttgct ttggagctac ttgaaaatag cccatttcca atcgtttatg
     1021 gagataaagg atatgtggat agacagacaa aggcagcgtt agcagactgt ggtatccagt
     1081 taatttctca actcagaaaa aacatggtgg gttattcatg gctagaaaat tacaaaataa
     1141 gtcgattgag gaaaccagtg gagactgtat tttctagttt agagcagttt ggaatggagg
     1201 ctttacgttg tcgaaacatt caggcgctta aatttaagac agaggcaata ttacttatct
     1261 attctctttt gcttaaaagc agtcatactg aatttggtat cagtttaaaa tattcccttg
     1321 cttacgcttg attaactagc acaacgggtt attaactata aaaccccatc ttcacaacat
     1381 aaaatggtta tgctaaagat gattacagga tagactatct cagagaccac atcaaggaaa
     1441 tgcgagatgc agacaccctt gacggaatag acctactagg ctacacgacc tgaggagcaa
     1501 ttatttagtt tctgcaggaa caggtgagat gactaaaaaa tattgcttta tctatgtaga
     1561 ccgtgatgat tatggcaatg gcacacaaaa aagaagcaag aaaaaatcat ttgactggta
     1621 caaaaaagtg attgcttcta atggtgaaga tttagattcc caatttgtaa aattaagcta
     1681 gacagaaaaa gccatctatg ttaggctcaa ataaactacc acatttgtct gaaaggaact
     1741 aacataaatg acctatactc atcttaccac agaactaatt ggaatcaaag acaaaaatat
     1801 caaaattctc ttcgttttga aacatcagac ccatctagaa atcagggcaa agctagatta
     1861 cgacagccct cgttgtcctc attgccaagg aaagtgtatc aagtacgatt ttcaaaagtt
     1921 gtcaaaaatc cctattttag attgtcaggg gtttccaacc tgcctcctgc ttaaaaaacg
     1981 ccggtttcaa tgcaaatctt gcaaaaaagt gaccgtagct gagacagctc tagtcaagaa
     2041 aaactgtcag atttcccaac ctatttggga gaaagtcaca caactccata cagaaaatat
     2101 gaccaatata gccatcgcta ggagactaca tatctccgtg tcggtcgtcc agaggaaact
     2161 ggctcagttt caatttgagc atgattttac gaaattacca aaagtcttga gctgggatga
     2221 atttagtcgg aacaagggaa aactcgcctt tattgctcag gattttgaga caagacggat
     2281 tgtgaccatt cttgaaaata accgccaaac caccatcaag aactatttct acaagtatcc
     2341 tagggcggtc agagaaactg tcgaggtcgt aacagtggac atgtcgggta gctatattcc
     2401 tatcatcaaa caactatttc caagggctaa aattgtcctt gatagatttc acattatcca
     2461 acacctgagc cgtgctatga tgacaactag aattaatatt atgaagactt tcgataagcg
     2521 ttccctacct tatcgatcca tgaaaaatca ccggcgtatt ctccaaaaag atagtcgtaa
     2581 actgtctctg aatcgcttct tttctcgcac ttttgggcaa acagtaacac cgagagaagt
     2641 tgtccagaag acattgaatt tctcagatga actgaaattc tattacgaac tctaccagat
     2701 ccttctcttc catttccaag agatgaactc gaaatatttc ttcgagcttc tagaagacaa
     2761 gctggatctt gtcaatcttg cctttaaaac tgtttttaaa acttttctaa agtataaaac
     2821 gtacatcacg aacgccatgg agcttccata ttccaatgct aaactggaag cgaccaataa
     2881 actcatcaaa gacatcaaga ggcaagcctt cggctttagg aactttacga actttaaaac
     2941 taagatatat atttctttaa acatcaaaaa tgagagaacg aatttcgtcc tctctaggtg
     3001 ttagcttttc gtctacccac tacagttgac aaagagccaa aaaatccttc ggagacaatc
     3061 ccatcctcca aggactttct ctagaaatca aaaaagggga agttgttgtc atcctagggc
     3121 catctggttg tgggaaaagt accctccttc gttgcctcaa cggcttagaa agtattcaag
     3181 gtggagatat tcttctggat ggtcagtcta tcgttgaaaa taaaaaagat tttcacctag
     3241 ttcgccaaaa gattggcatg gtcttttaaa gttatgaact ctttccccat ctggatgtct
     3301 tacaaaacct catcctaggc cctatcaaaa ctcaaggatg ggacaagaaa gaagtaacgg
     3361 aagaagcttt gcaattacta gatcgtgtcg gtttgctgga taaacaacat agctttgccc
     3421 gtcaattatc tggtggacag aagcaacgtg ttgcaattgt ccgtgccctc ctaatgcatc
     3481 cagaaatcat cctttttgac gaggtgactg cttcgctgga tccagaaatg gtgcgtgagg
     3541 tgctggaact tatcaatgat ttggcccaag aaggccgtac catgatttta gtaacccacg
     3601 aaatgcagtt tgcccaagcc attgctgacc ggattatctt cctcgaccaa gggaaaatcg
     3661 ctgaagaagg aacagctcaa gccttcttta ccaatccgca aaccaaacga gcccaggaat
     3721 ttttaaacgt ctttgacttt agccaatttg gctcatatct ataaaggaga ttcttatgaa
     3781 actattcaaa ccactcttaa ctgttttagc acttgccttt gcccttatct ttatcactgc
     3841 ttgtagctca ggtggaaacg ctggttcatc ctctggaaaa acaactgcca aagctcgcac
     3901 tatcgatgaa atcaaaaaaa agcggtgaac tgcgaatcgc cgtgtttgga gataaaaaac
     3961 cgtttggcta cgttgacaat gatggttctt accaaggcta cgctacgata ttgaactagg
     4021 gaaccaacta gctcaagacc ttggtgtcaa ggttaaatac atttcagtcg atgctgccaa
     4081 ccgtgcggaa tacttgattt caaacaaggt agatattact cttgctaact ttacagtaac
     4141 tgacgaacgt aagaaacaag ttgattttgc ccttccatat atgaaagttt ctctgggtgt
     4201 cgtatcacct aagactggtc tcattacaga cgtcaaacaa cttgaaggta aaaccttaat
     4261 tgtcacaaaa ggaacgactg ctgagactta ttttgaaaag aatcatccag aaatcaaact
     4321 ccaaaaatac gaccaataca gtgactctta ccaagctctt cttgacggac gtggagatgc
     4381 cttttcaact gacaatacgg aagttctagc ttgggcgctt gaaaataaag gatttgaagt
     4441 aggaattact tccctcggtg atcccgatac cattgcggca gcagttcaaa aaggcaacca
     4501 agaattgcta ggcttcatca ataaagatat tgaaaaatta ggcaaggaaa acttcttcca
     4561 caaggcctat gaaaaaacac ttcacccaac ctacggtgac gctgctaaag cagatgacct
     4621 ggttgttgaa ggtggccatt aactcttaaa agggactgga ttttaagctc caatcccttt
     4681 ttaagatttt acctataaca tcctgagtct atctaagatg ttcaatctga acacagtgta
     4741 catactttat cttctattgc atatacttta tcacataaga tacgaatatc ctcttcacta
     4801 tgactagcaa tcaaaattgt tgtccctttt tcactagaga gctttctaaa caatgttctc
     4861 atattttcta cacttgattt atccaaggca ttcataggtt catctagtaa aagaatagag
     4921 ggattctcca taattgcttg agcaatccct agctttttcc tcatacctag cgaataagtt
     4981 ttaactttct ggtctttttg ctcatataga ccaactattt tcagtgtatc attgatttcc
     5041 tgattaccaa ctactcctcg tatgcttgcc aaatattgta aattcttaaa gccactataa
     5101 taatttataa aaccaggttc ttcaatcaaa gctcccaaat tagctggaat ttttctctca
     5161 ggaacaatat tttccccatt gattaacact tctccataag acggactata taaaccagct
     5221 attaatttaa acaatacact tttccctgag ccattcgcac cagtaattcc tataatttcc
     5281 ccctgtttac aactaaagtt aaggttttga aaaacacatg tcttttttaa tttcaactca
     5341 atatttttta atgtaattat ttcattcatt ctataaacct cctcttttga cgagtgaaat
     5401 agaaaatgct ttgaaaaaga aagactaaaa atagcaactg aagaaataaa tctcgtccta
     5461 tatctccatt ccctcgattc aaaatataaa atagataatt agttcgattt cctacaaata
     5521 gaccaccaaa cacaatcatg agtaaaaaga aactaacgca agcaaagttc atttgtacat
     5581 tcgctcctag tgcgtataac ataaagcaaa acaagactaa cacacaagca ttcaaagaat
     5641 caactataaa caaaactcct atatcccagt ttggtaactg taacataaat tgaatcacta
     5701 gaacttttac catgattaaa atgagtccat aaagaaaaca ggtccaaatc tgatacctaa
     5761 tccagagctt aatagaagaa aatcgaatca cttccataaa gaaatcggat gctcttctac
     5821 gatatacaat tgctagaaaa aatgtatgaa taataaacca atgaagcaac catatagata
     5881 agactaaaaa agagttttga ctcagattag gcccttttaa aatttctata acaagtctat
     5941 catttccttc taaccaatac cataatccta aacaaatcaa tatccaaaaa agaacataac
     6001 cccaaaagta cttggtatag attatctgat tcaacctcca catgtgacta cttaactttc
     6061 ccatttccaa cttttacact ctcctccagt ttctatgaac agaaaataca gtcaatggaa
     6121 ttatgataga tagtaatgta agccaataaa tcaatgcata cggattggaa tttaccatat
     6181 actgaaaaat tggcaataat ccaattatcc cattgtccaa ctgataaatc cagaataagg
     6241 attctacaaa taaaaaagta aacagaaata ctaagctcat gtttgatttt ttaaaccaag
     6301 aaaaactgct aatagtaagt aaggataaaa agaaatagta tgctatataa gagaaaaaaa
     6361 atcctataaa gaaactagca ttgtttgcaa tacttatacc ataaaattct cttaaaaaat
     6421 caacctcctt tatctccaaa gagaagctaa aaccattact aaatgcaatt agaaaaatca
     6481 ataaaaataa agtcgccgtc caaatccccg tactaagagc tgctaatttg aaactaaaac
     6541 tggtaaagtg cttaattgat ttcagacgaa tgcgacactc caacctatta aaatagttat
     6601 tcatcaaata aaaaaagaac aatatatatg tgaacggaaa gcaatatact ccagtcgtca
     6661 tatcttgaag taaaactaag atccattcta atacatttgg atggattgaa tattggcgac
     6721 agcgcaataa atatactgta ctagataaaa cacaggatag cagtaatata aaataaacca
     6781 atactgataa aaaatctttt ttgtaaaatt gaacaaattg tttcattata cgtagtcctc
     6841 tgaatgtaga aaaaatgtac cataaacaac caaacaacta acaaataaaa taaaagcaag
     6901 atgcccacta actaaggaaa gactgatatc tttctgatat cccaaagcta atgttgtcac
     6961 aggttctaag taagatagcc ctaaaatagc ccaaaaaata ccaccaacca tcatataggc
     7021 aactgggatg aaaatagctc ctattttttt cttcactagc aaagcactag ctagtccaaa
     7081 aatagagaac acagcgcccc aaactccata ccagagagtc gttacaagac tatagagaaa
     7141 ctgattggaa tcaaataatt cttttaaggc accactataa tctccaatat aaatttcctg
     7201 ataaggagtc actaaaagat taattcctaa taataataaa taggggagaa aaaagactag
     7261 aaaagaagaa ataattacag tactacccac aatagccaga tacttctttt tagaaattcg
     7321 acacaattgt gctgttagaa aatgactctc agcatcctct attatctgac tagaataggg
     7381 cagtgtacag ataagtgcag ctactaggct aatcggtgaa aatcctcgaa tagaagaagc
     7441 ggcaaaaaaa atcgataaac cttcaatttt ataaatacca ttgaaagcaa ggaaatttcc
     7501 taaactcatg caaagaaggg tcaaaaataa agacatataa aatcgaggtg attgaacgac
     7561 tcgtacaaga ttacaaatga aaaattccat ccttactcct ccttataata aaaatagggt
     7621 gtagcattct tttttcatgc tacacccaca atcaaccatc tttaaggctt actctgacaa
     7681 gtaagttaat aagaatctgg attccaagaa cctgaagtat gaattcttac atgatttcca
     7741 aattgtggcg ccatagctaa tctagtacca gaaccaatat aattgtcacc acctccatta
     7801 tagtacatga caatcctaga gccagacccc aatgaatata ccggggtaat atctgaccca
     7861 ttataggcgc tacgaataga ggtatttaac cttttaccgc caccagtgct gtcactatta
     7921 ttaattccag cagaggcgtt ttctttctca agctcactag ttgtatccga accccaacgc
     7981 ggcaacgtta aatcataatt tccaatctgt ctagctaaaa ctgtagggag aaacaaacta
     8041 gatgcaattg taactacgca aaaaaggaat atatttttct tcttttcatg acatcgtcct
     8101 cttaagaagt gataaacaag atagttgatt gatcaatttg atacatatta cattttcatt
     8161 atatcaataa aagaaagcgt tgtcaattat tttatttaaa atattgtcat attttaaata
     8221 aaatggtaaa agagactcgg tagcctcgtc tctctttatc ttactgacct aaccttcttg
     8281 ccaattttct tggtcttctt taaagcgttt tagaagatta aggccctctg gcgtgatgta
     8341 accttcttct tgggctagat ggataagctc gctatagttt gaaagcgtca caagtttaac
     8401 atcagcatct gcaaagttct tatctgcttt tggcaattgg tagctgaaaa tcgctacaac
     8461 tccaagtaca tctgctcctt ctcgcttggc tgctgctaca gcttcaagaa ctgaaccacc
     8521 cgttgaaata aggtcttcaa ccactaccat tttttgacct tgagctacgc gaccttcgat
     8581 ttgattacca gctccgtggt cttttggttt gctacggatg taggcaaaag gcaagtccat
     8641 cttatcagca ataatggctc cgtgtggaat ccctgctgtt gcagttcctg caatcacttc
     8701 tacttcagga aaggcttctt tgatagcttc cacaaaacca ttttcaatta gggtacgagt
     8761 ttctggatag gctagtgtca cacgattatc agtgtaaatc ggtgacttga taccagatgc
     8821 ccaagtgaag ggttcctctg gtttgaggta aacggcttgg attttcaaga ggtggctagc
     8881 gatatcttta gcaagtgtca tggtattctc cttttatttt tctaatctag ttctttaatt
     8941 ccagtcctgt gtccattcat ccttgatggc atgataagct gcaacaggat cctcagcttg
     9001 ggtaatggga cgtcccacta cgatatagtc actgccgatt tgataggcat cagcaggtgt
     9061 catgactcgt ttttgatctc caactgcaac accagctgga cgaatccctg gtgtcagaca
     9121 gataaaatct ggattggtag cctgcttgat gacttgtact tcctgagccg agcaaacaac
     9181 accatccaag ccagcttcag ctgtcttctt ggcatagtga atcacagact cttgcagact
     9241 gatttggata ttttgaaact cctgcatctg ggcttctgac gttgatgtca gctgcgttac
     9301 agcgatcaat ttggcttgac tcccaagacc ttcacgcgcc gccttcatca tctctacacc
     9361 accagccgca tggacattag tcatatcgac accaagctga gacaagacct tcatggctga
     9421 cttgactgta ttaggaatgt catgaagttt gagatccaaa aagacactat gacccaaacc
     9481 ttttaagtag gacacaatct caggccccgc tgcgtaataa agctccatcc ctaccttgag
     9541 ataaaggctt tcttctgctg ggaaaagagc taaaaattcc ttgaccgcct caaaactagg
     9601 aaaatcaaga gcaatgattg gacgatgttc tcgcataggt ttctcctttt acctttacta
     9661 gtgagagagt ctggccaaca gaagccacga aaaaaggaac ctgccaacag caaggttcca
     9721 cgaaaaatgg gtagtctcca ccctttcacc gtctaacctt agctgcctct ctggactgct
     9781 ttaaaggttt tttactattc tattatttct actagcactt gtcaagtaaa aacatggtca
     9841 cgtatgtgtt gactgctatt gaacacctca caagactctt tccaaaagaa tagttaaaga
     9901 ctttcactta ggacagagaa aaagagtttg cttgttaccc tttaattgaa caaatgggaa
     9961 ttctgtttta ttttgcggat gcctattcat cttggcaaag gggaagtaat gagaatgcga
    10021 atggacttct tcgtgagtat tttcttaaac cgatttggca acaattaccg aaaaaatcct
    10081 taatggtgct ttgctagctt attaatcacc gtccccaaaa atacttggat tacaagacag
    10141 gttttgaagc acttatagag gagatttaaa aatgttgcat tttttattgc aatttatcag
    10201 ttatcttatc acccaaaact tctgcaatta gtatgagcac tattgttatt tttctttttt
    10261 cgtacactca aatcaaaata tagcaataag actattctgt agaattgctg tcaaaaagat
    10321 cagttcattt ttccttccca cttgtgttta taatcattaa aataactcaa ttaagaaatt
    10381 ttctttttcc taatagttat cgtaattaaa gttaatagaa gaacaatcca aataagtagt
    10441 gttagattag gaattagagt ttcattccat gaaaatccct cccattttgt gaaaaactta
    10501 gtaaacagtc ccataaaact ataatctgtt atcttcgcaa ctgtcttatc caaaccagat
    10561 agcatcggta agaaagcaac taaaatcata gcaggaagac tgataacctg agctactact
    10621 tggctcttcg cggttaaacc tatcaataaa tagaataaaa tgatggataa agaggttaga
    10681 agaacgattg taatataatt aaaagtatgt acaattgtaa ctcctaaaat aagaggagta
    10741 gttcccataa tcacaaaagt tagcaaaaaa ggaagaaaca tcgttgataa aatgtattcg
    10801 gatcctttaa caccactcaa cagaagagtt tgtaaattgt acttttcttt ctcttcagac
    10861 aagataatag ttataggact tccaacagcc aaagccaaag aaaaaggtaa acacatcatc
    10921 aaaagaacta atgcctgttg atcgttgacc ttcccctgtg tttccataag atatttataa
    10981 aaatatgtga aagcaaaagg cactaaaact tgcaataaaa tactcttatt ggaaaggata
    11041 atttgacaac gcaaccatac caaagccaga aaccgtttaa gcatttagct ttcctcctgt
    11101 taatgtgata aaaatatctt ctaaagtagg ttcacatgaa tgaattgaaa aaatattttc
    11161 cagatcagcc tgagatacct gttctagtga tgtaaaatca aaagttatct gattcccatt
    11221 ataatctgta accttaatct ttttatcttt attatatctt tgaatgagtt cagaaggagc
    11281 tccttgctca actaatttcc ctttatttaa taaggcaaca taatcacata aaagagttgc
    11341 ttcattcata tcatgagtcg ttagaaaaat cgttgtccct gctgttttca attctaaaat
    11401 taactcatga attgttcgag aagttgtggg atctagacct gaggtcggtt catccagaaa
    11461 gagtacagcg ggtttgttga taagagctcg tgctaaaagc attcgttgcc tcattccagt
    11521 ggataatttt cctgctacca tcttgcaact atcatataat cctactcgct ttaacaaatt
    11581 atcaacacgt gatttactaa tattataaaa tttactataa aaaagaagat tgttatacag
    11641 agacattttc tcataaaatc cacttgtatc gctaaccaat ccaattctct ttaattcacc
    11701 gcttgttaaa ttttgagatt tttgtcccaa aataatagat tgtcctttat cggcaaggaa
    11761 ctgcccagtc agaatattaa tcgttgtggt ctttccagaa ccagatggtc ctaaaaatcc
    11821 aaaaatctaa ccttctttaa cagtgaagct tatattattt aaagctattt tatcaccaaa
    11881 actttttgat aaatggctaa cttcaatcat actcattgca cctcctttat attctacatt
    11941 tttacttaac atctatttac ttatctttat caaataaac
//
LOCUS       DAVLZS010000052        11798 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLZS010000052 DAVLZS010000000
VERSION     DAVLZS010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11798
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.052"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            110..763
                     /locus_tag="VYO88_001678"
     CDS             110..763
                     /locus_tag="VYO88_001678"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1719735.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            773..1237
                     /locus_tag="VYO88_001679"
     CDS             773..1237
                     /locus_tag="VYO88_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1719736.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1250..2518
                     /locus_tag="VYO88_001680"
     CDS             1250..2518
                     /locus_tag="VYO88_001680"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1719737.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     NATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2532..2792
                     /locus_tag="VYO88_001681"
     CDS             2532..2792
                     /locus_tag="VYO88_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719738.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2803..4164
                     /gene="pdrM"
                     /locus_tag="VYO88_001682"
     CDS             2803..4164
                     /gene="pdrM"
                     /locus_tag="VYO88_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1719739.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4318..5286
                     /locus_tag="VYO88_001683"
     CDS             4318..5286
                     /locus_tag="VYO88_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1719740.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5302..6294
                     /locus_tag="VYO88_001684"
     CDS             5302..6294
                     /locus_tag="VYO88_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1719741.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSVRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6512..7555
                     /locus_tag="VYO88_001685"
     CDS             6512..7555
                     /locus_tag="VYO88_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1719742.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7619..9304
                     /gene="lpdA"
                     /locus_tag="VYO88_001686"
     CDS             7619..9304
                     /gene="lpdA"
                     /locus_tag="VYO88_001686"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1719743.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVSGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9368..10357
                     /locus_tag="VYO88_001687"
     CDS             9368..10357
                     /locus_tag="VYO88_001687"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1719744.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10430..11500)
                     /gene="xerS"
                     /locus_tag="VYO88_001688"
     CDS             complement(10430..11500)
                     /gene="xerS"
                     /locus_tag="VYO88_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1719745.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGCKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
BASE COUNT         3482 a         2216 c         2652 g         3448 t
ORIGIN      
        1 attcaaatcg tatatagtcg atttattaaa tctttagata aattgtaaaa agtggtttcc
       61 atagccactt tttgctataa tagaggcagt aaaaatgaag gagtcagcta tggaacactc
      121 gtcttggcat gctttgatta aggcgcaatt acctgagggt tatttcggga aaatcaatca
      181 gtttatggag caggtctatt ctcaggggat tatttatcca cccaaggaaa aggtttttca
      241 ggctctcttg acaacactgc ttgaagaagt taaggtggta attctagggc aagaccccta
      301 tcacggacca ggtcaagcgc agggcttgag tttttctgta cctgactcta tcccagctcc
      361 accatccttg caaaatatct tgaaagaatt gtcagatgat atcggagtta agaaatctca
      421 tgatttgaca gcttgggctg agcaaggagt cttgcttctt aatgcttgtt tgactgttcc
      481 tgctggacag gccaatggtc atgctggtca aatctgggag ccttttactg atgctgtgat
      541 tcaggtggtc aatcatctag atagaccagt cgtttttgta ctctggggag cttatgcacg
      601 taagaagaag gccttagtta ccaatcctca tcacttgatt atcgaatcag cccatccaag
      661 tcctttgtcg gtttatagag gattttgggg ttccaagccc ttttccaagg ccaatgcatt
      721 cttaaaagag acaggacaag agccaatcga ttggcttaga taaggagaaa atatgcctca
      781 gttagcgacg atttgctaca ttgataatgg gaaagaactg ctcatgctcc atcgtaataa
      841 gaaacccaat gatgtccatg aagggaaatg gattggtgtg ggtggtaagc tagagagagg
      901 agagacgccc caggaatgcg cggcgcgtga aatccttgaa gaaacagggc tcaaagccaa
      961 gccagttcta aaaggtgtca tcacttttcc tgaatttaca ccagatttag actggtacac
     1021 ctatgttttt aaggtgacgg agtttgaggg cgacttgatt gactgcaatg aggggacgct
     1081 agaatgggtt ccctatgacg aggttttgag caagccgact tgggaaggtg accacacctt
     1141 tgttgagtgg cttttagagg ataaaccctt cttttcagcc aagtttgttt atgatgggga
     1201 taaattgttg gatacccaag ttgatttcta tgaataaagg agaaagcaga tgctactaat
     1261 caaaaatggt cgtgtaatgg atcctaagtc tggtttggat caagtttgtg atgtcttagt
     1321 tcaagatggg aaaattatca aaattgcgcc tgagatcacg gaagaaggag cagaaacgat
     1381 taatgctact ggtcttgtgg ttgctcctgg tttggtcgat attcatgtgc atttccgtga
     1441 acctggtcaa acacataaag aagacattca tactggtgcc ctagcagccg ctgcaggtgg
     1501 ttttactact gtcgtcatga tggctaatac cagtccaacc atttcagacg tggagacttt
     1561 gcaagcagtt ctccagtcag ctgccaaaga gaagattaat gtcaagacag ttgcgaccat
     1621 tactaaaaac tttaatggta aaaacttgac tgactttaag gcgctcttag aagctggtgc
     1681 ggttggtttc tctgatgacg gtattccgct tgagagcagt aagattgtca aggaagccat
     1741 ggaggaagcc aaaaaactca atacctttat cagccttcat gaggaagatc caggtttgaa
     1801 cggtgttctt ggctttaatg aaaatattgc tagagaacat tttcatatct gcggtgctac
     1861 tggggtggct gagtacgcta tgatggcgcg tgatgtcatg attgcctatg caactaaagc
     1921 ccatgttcac atccagcatt tgtctaagga agaaagtgtt aaagtagtgg agtttgctca
     1981 ggggttaggt gcagaagtca cagcagaagt agcgccacag catttctcta agacagaagc
     2041 acttctttta acacaaggta gcaatgctaa gatgaatcca ccgcttcgtt tggaatcaga
     2101 ccgtcgtgcc gttatcgaag gtctcaaatc aggtgtcatc acagttattg cgactgacca
     2161 cgcgcctcat catgtagatg aaaaaaatgt tgaggatatt accaaagcgc catctggtat
     2221 gactggctta gaaacatccc tgtctctcag cttgacctat ttagtagaag ctggtgagtt
     2281 gagcttgatg gaattacttg aaaaaatgac atacaaccca gccaagcttt acaactttga
     2341 agcaggttac ttggctgaga atggtccagc agatatcact atttttgatg ccaaggctga
     2401 ccgccttgtg gactcccatt ttgcttccaa agcagctaat tcaccattca tcggtgaaac
     2461 cttaaaaggg caggttaaat ataccatctg taagggacaa atcgtctatc aagcttgata
     2521 ggagttagaa tatgaattat tttcgaaaac gtagggagag acaagcgaaa tctaatagtg
     2581 gaatttactg tcccgcagct aatcgttcca aaattcaata tgaaactaaa gaaaaagctg
     2641 accatgcggt tcaatatgat aacggaggtt tagttagaag ctattattgt cgtacatgtg
     2701 cgtgttggca tactacttca aaatctaata aacctccgct aagtttgaaa aactatggtc
     2761 tgaaactctt tggtttagat aaatcagaat agaaagagaa gtatgtataa gacaaagtgt
     2821 ttacgagaga agttagtatt atttttaaaa attttcttcc caatcctgat ctaccaattt
     2881 gccaattatt ctgcctcttt tgttgatact gcaatgacag gtcaatacaa cactatggac
     2941 ttggctggtg tatctatggc aaccagtatc tggaatcctt tctttacatt tctaacaggg
     3001 attgtgtcag ccttggtgcc tatcattggt caccatcttg gtcgaggcaa aaaggaagaa
     3061 gttgcgtctg atttttacca atttatttat ttggccttgg gcctatctgt ggtcttgctg
     3121 gggatggtac ttttcttggc accaacaatc ttgaatcata ttgggttaga agcagcagta
     3181 gcggcagtag cggttcgcta tctttggttt ttatctatcg ggattatccc cttgttgctc
     3241 tttagcgtca ttcgttcctt gctggattcg ctgggcttga ccaaactgtc catgtacctc
     3301 atgcttttgt tactccctct caatagcgga tttaactatc tcttgattta cggtgccttt
     3361 ggtgttccag aactgggagg ggctggtgct ggtttaggaa catccttggc ctactgggtc
     3421 ttgcttggga tttctgttct ggttttattt aaacaggaga agctcaaagc cttacacctt
     3481 gagaaacgaa ttccacttaa tatggataaa attaaggaag gagttcgttt aggtctgcct
     3541 attgggggaa ctgtcttcgc ggaagtggct gtcttttcag tggttggctt gattatggct
     3601 aagttttcgt ccttgattat agctagtcac cagtcagcta tgaacttttc aagtcttatg
     3661 tacgcctttc ctatgagtat ctcatcggct atggctattg tcgtttccta tgaagtggga
     3721 gccaagcgat ttgatgatgc gaaaacctat attggtctag gaagatggac tgctctcatt
     3781 tttgcggcct tcaccctaac cttcctttac atttttaggg gaaatgtggc cagtctttat
     3841 ggtaacgacc caaaatttat cgatttgaca gcgcgttttt taacttatag tcttttcttc
     3901 cagttagcag atacctttgc ggcgccgctt cagggaattt tgcgggggta taaggataca
     3961 gttattcctt tttaccttgg tttgcttggt tattggggcg tagcaatccc tgtggctacg
     4021 ctatttgatt ccctaacaga ttttggagct tattcttact ggatcggctt gattattagt
     4081 ttgattgtga gcggggcgct ctaccgttgg cgtttaactg tgattatgaa gagatttgaa
     4141 tctttagcaa aatccaaacg ctaaaaagtt tgtgaaaaaa tattcttgac aagaaaatcc
     4201 cttgttttca cggggttttc ttttttattt tgtgaaattt cttttagaaa aactttgaca
     4261 gtatttgcca aaagcggtaa aatagtaagg taagaagaaa gttagaaagg caagaagatg
     4321 tcaactttag ataaaaatct tttgctagaa atgttccgta agatggaaga aatccgtcgc
     4381 atggacttaa aaattgcaca attagtaaag aaagggaaag tgccaggaat gacgcacttt
     4441 tctgttggtg aagaggcagc taacgtgggg gctatgttag ctctcaatcc agatgatctg
     4501 attacctcaa accaccgtgg acacgggcaa gctattgcta aagggattga cctcaacgga
     4561 atgatggctg aaatccttgg taaatacact ggaacctgta aagggaaagg tggatctatg
     4621 catatcgctg accttgatgc tgggaacctt ggtgccaatg gtatcgtagg tggtggtatg
     4681 gggatcgctg tcggtgcagc cctcagtcag caaatgcaaa ataccggtaa aatcgttgtc
     4741 tgcttctttg gagatggtgc gaccaatgaa ggtgttttcc acgaagcagt gaacatggct
     4801 tctatctgga acctgccagt cattttctat tgcattaaca acggttacgg tatctctgcg
     4861 gatatcaaga aaatgaccaa tatagaacat atccatcaac gtagcgccgc ttatggaatt
     4921 cctggaatgt tcatcgaaga cggtaacaat gtcatcgatg tctatgaagg atttcagaaa
     4981 gctgtggacc atgttcgcag tggcaatggt ccagtcttga ttgaaagtgt aacttatcgc
     5041 tggctcggtc actcatcatc tgaccctggt aaatatcgta cgcgtgaaga agtggaattg
     5101 tggaaacaaa aagatccaat cgaaaacctc cgcaattacc ttattgaaaa taacattgca
     5161 agtgccgaag aattggaaga aatccaagcg caagtaaagg aagcagtaga agcttctgtt
     5221 aaatttgcag aggaaagccc attcccaccg cttgaatcag cctttgaaga tatttacgca
     5281 gactaaggag aaagagataa aatggaaaca aaaacaatgt ccttccgtga caccattatc
     5341 cttgctatgt ctgaggaaat gcgtcgcgat gaaaatgtgt tcttgatggg agaagacgtc
     5401 ggtgtcttcg gaggagactt cggtacttct gttggaatgc ttgaagaatt tggtccagaa
     5461 cgtgtccgtg actgtccgat ttctgaagct gccatctctg gagcagcagc aggagcagcc
     5521 atgacaggac ttcgtccaat cgtcgatatg accttcatgg acttctctgt tattgccatg
     5581 gacaatatcg tcaaccaagc tgctaaaaca cgttacatgt ttggtggtaa aggtcaggtt
     5641 ccaatgactg ttcgttgtgc agctggtaac ggagttggct ctgccgccca gcactcacaa
     5701 tctctagagt cttggtttac tcacattcca ggacttaagg tggtggcacc tggaacacct
     5761 gcggacatga aaggcctgct taagtcttct gtccgtgata acaacccagt tattatactt
     5821 gagtacaagt cagaatttaa ccaaaaaggg gaagtgccag ttgatccaga ctacacaatt
     5881 ccacttgggg ttggtgaaat caaacgccaa ggaacggatg taacagttgt tacttatgga
     5941 aaaatgcttc gccgtgtggt tcaagctgct gaagaattag cagaagaagg aatttcagtt
     6001 gaaattgttg acccacgtac ccttgttccg cttgataagg atatcatcat aaactcagtg
     6061 aagaagactg gtaaggttgt tctggtcaac gatgcccaca aaacaagtgg ctatatcggt
     6121 gaaatttcag ctattatttc agaatcagaa gcatttgact atctagatgc accaatccgc
     6181 cgttgtgcag gagaagatgt gccgatgcct tatgcacaaa acctagaaaa tgcaatgatt
     6241 ccaacagttg aaagtatcaa agatgcaatc cgaaaaactt ataacaaaga atagagttac
     6301 ataagataag ttatgtaaat aaaataaagc tgacgagaaa ctttgtatct tttaggtgca
     6361 gagctcttcg tcattaatat cttatattcg agcacgggct aaaagctcgg aaaaaagata
     6421 aatctccttg gcttcatcga agccatcgtc gatttcctat ttttcagtcg cttttgacgc
     6481 cctttgtatc ataaatagaa ttggagaggt catggctgat gacaagctaa gagcgactcc
     6541 tgcagctaga aagttagcgg atgatttagg gataaacctc tacgacgttt ctggctcagg
     6601 tgcaaacggt cgtgtccaca aagaagacgt ggaaacttat aaagacacaa acgtggttcg
     6661 catttcgcca cttgcaaaac gaattgccct cgaacataac attgcttggc aggaaatcca
     6721 aggaaccggt catcgtggta aaatcatgaa gaaggatgtt ttggccctgc ttcctgaaaa
     6781 tatcgaaaac gatagcatca aatctcctgc tcagattgaa aaagtggaag aagtccctga
     6841 taacgtaaca ccatatggtg aaatcgagcg tattccaatg acaccaatgc gtaaggttat
     6901 tgcccaacgc atggttgaat cttacttgac tgcgccaacc ttcaccctca actatgaagt
     6961 tgatatgact gaaatgttgg ctcttcgtaa gaaggttctt gagccaatca tggaagcaac
     7021 tgggaagaag actactgtaa cagaccttct ttcgcttgca gttgttaaga ctcttatgaa
     7081 acacccatac atcaacgctt cattgacaga agatggcaag actattatca ctcacaacta
     7141 tgtcaatctt gccatggcag ttgggatgga taatggattg atgacacctg ttgtttacaa
     7201 tgctgagaag atgagtcttt cagaactggt ggtagccttt aaggatgtta ttggccgtac
     7261 cttggatggt aaattggctc caagtgagtt acaaaattca acattcacaa tcagtaattt
     7321 gggaatgttt ggtgttcagt cctttggtcc gattattaac caacccaact cagctatcct
     7381 tggtgtcagt tcgacaatcg agaagccagt tgtcgtcaat ggtgaaattg tgattcgccc
     7441 aatcatgagt ttaggattaa ccattgacca ccgtgtcgta gatggtatgg ctggtgctaa
     7501 gtttatgaag gacttgaaag agttgattga aacgccaatc tcaatgttaa tttaagagca
     7561 agagtattca tttttaagat atagataaag gaaggaagac atggccttag aagtaattat
     7621 gccaaaagcc ggcgtggata tgacagaagg acaaatcgtc caatggaata aaaaagtcgg
     7681 agaatttgta aaagaaggag aaatcctttt ggaaatcatg actgataaag tcagcatgga
     7741 attggaagcc gaagaagatg ggtacttgat tgccattctc aaaggagatg gtgaaactgt
     7801 ccctgtaacg gaagttatcg gttaccttgg tgaagaaagg gaaaacatcc caacagctgg
     7861 agcagcatcg ccagaagcta gccctgtacc tgtagcaagt acctcaaacg atgatggtaa
     7921 gagcgatgat gcttttgata tcgttgtgat tggtggaggt cctgctggtt atgttgcagc
     7981 cattaaagct gcccaacttg gcggtaaggt tgcccttgtt gagaaatctg aacttggtgg
     8041 aacctgctta aaccgtggat gtattccaac caagacctac cttcataacg ctgaaattat
     8101 tgaaaatatc ggtcatgctg caaatcgtgg tatcgtgatt gaaaatccta acttcactgt
     8161 tgatatggaa aaacttttag aaactaaatc taaagttgtt aatactcttg ttggtggtgt
     8221 tgcaggactt cttcgtagct acggagttac tgttcataaa ggaattggta caatcactaa
     8281 agacaagaac gtcttggtaa atggttctga attgcttgaa accaagaaaa tcattcttgc
     8341 tggtggttca aaagtcagca agatcaacgt ctctggtatg gaatctccac ttgtcatgac
     8401 tagtgatgac attcttgaaa tgaacgaagt gccagaaagc cttgttatca tcggtggtgg
     8461 agttgtcggt atcgaactcg gtcaggcctt catgacattt ggttcaaaag tgactgttat
     8521 cgaaatgatg gaccgtatag ttccagctat ggatgcggaa gtttctaaga accttcgctt
     8581 gatccttgag cgtaaaggaa tgaccatctt gactggtact aaactgcaag aaatcattga
     8641 ggaaaatggt caacttcgta tcaaggttga aggaaaagac gatatcatcg caagcaaagc
     8701 tcttctttca attggtcgta tgccagacct tgaaggtatt ggagaggttg agtttgaatt
     8761 ggatcgtggt tgtatcaagg tcaacgaata catggaaact tcagttccag gcatttatgc
     8821 accaggtgac atcaacggta ctaagatgtt ggctcacgca gctttccgca tgggtgaagt
     8881 ttccgctgaa aatgccctta aaggaaatca tgcagttgcc aaattgaatt tgactcctgc
     8941 agccatctac actctccctg aagtagcagc agtaggtttg acagaagaac aagcccgtga
     9001 gaaatacgat gttgccatcg gtaagtttaa ctttgctgct aacggtcgtg ctattgcatc
     9061 tgacgcagct caaggtttcg taaaagttat cgctgataag aaatacggag aaatccttgg
     9121 tgtacacatt attggtcctg cagccgcaga attaataaac gaagcatcaa gcatcatcga
     9181 aatggaaatc actgttgagg aaatgctgaa gaccatccac gggcacccaa cttactctga
     9241 agtgatgtac gaagcgtttg cagatgttct aggaatggcc atccattcac ctaagaaaaa
     9301 ataaaacgaa gatagattag actggaaggt tatttccagt ttctatcata taaagtaaag
     9361 ggatatcatg aaatacatta tcaatcattc aaatgacact gcttttaata ttgccttgga
     9421 agaatacgcc tttaaacacc ttttggatga ggatcaaatc ttcctacttt ggattaacaa
     9481 gccatctatc attgttggtc gtcaccagaa cactatcgaa gaaatcaacc gtgattatgt
     9541 tcgcgaaaat ggtattgagg tagttcgccg tattagtggt ggtggagctg tttaccacga
     9601 tttaaataac ctcaactaca cgatcatctc caaagaagat gaaaataagg catttgactt
     9661 caagagcttc tcaactccgg ttatcaatac cctggctcaa cttggggtta aagctgagtt
     9721 cacaggtcgt aatgaccttg agattgatgg taagaagttc tgtggcaatg cccaagccta
     9781 tatcaacggc cgtatcatgc accacggttg cttgctcttt gacgttgatt tgtcagtcct
     9841 cgcaaatgcc cttaaggttt caaaagataa atttgaatca aaaggtgtga aatccgtccg
     9901 tgcccgtgta accaatatta tcaatgaatt accaaaaaaa atcacagtcg aaaaattccg
     9961 tgatttactc ttggaataca tgaaaaaaga gtacccagag atgactgaat acgtcttttc
    10021 agaagaagaa ttggccgaaa tcaatcgcat caaggatact aagtttggaa cttgggactg
    10081 gaactatggt aaatcacctg aatttaacgt ccgtcgtgga accaaattca ctagtggtaa
    10141 ggttgaagtc tttgctaacg ttactgaatc aaaaatccaa gacatcaaga tttatggtga
    10201 cttctttggt attgaagacg ttgctgcagt agaagatgtc cttcgtgggg tgaaatacga
    10261 acgcgaagat gttcttaagg cgctaaaaac cattgatatc acacgctact tcgctggtat
    10321 tagccgtgaa gaaatcgctg aagcggtagt tggataaatc aaaaagaagt tggccaacta
    10381 accaacttct ttttttgata tttatttaca taatttaaaa tacgtaaaat cataaactat
    10441 ccagagcatt cttttgttca tcactaacaa tatgggtata gaggtcagtg acttgtgtgc
    10501 tagcatgtcc tagttggtga ctgactaaaa cttgtgattt agtcgcatca tagagcctag
    10561 ttgctagtgt atggcgcagt ttatggggtg ttacacgcac tttaaaatcc tctgagtatt
    10621 tagcaaccat tttctcaacg ctagaagcat cgatacgatt aggaacacct ctgtagagag
    10681 ttaaaaaaag ggctgtatct gttttttccg ttttatagcg ttgattccga atggccagat
    10741 aattctctaa ataaggttta gcaaaagcag cgacattgac tgagtcacgt ttgcaacctt
    10801 ttcgagtaac atcaataacc atcattttta gattgagatc tcttagatct agattaacag
    10861 cttcagataa gcgaacacca gatgccaaga gaagggcaat aatggctaaa tctcgttctt
    10921 tatttttgtt gaatgatgag agagctcgat ttgaaagctg ttgtgggtgc tcttgatcga
    10981 tataagttag aaaaccttct gtttcatcac ctagaaagag tttttgcttg atattttcag
    11041 ctctggcagc aagggtttct ttctttttct tggtggaaac ttttttcatt acattacgat
    11101 agaaataagg ttccccctga tcgttttcaa cctcctcggt tagatacttg taaagactag
    11161 aaagtgctga taaggttcga ttgatagttg tctgtgaaac accttgtttt gttgtattag
    11221 cattcagcaa gggacgttca cgtagataaa ggataaagga ttccatgtct ttcttagaca
    11281 tattttccaa aactgataaa ggaatatcgg atattttatc agcgtttgaa ataccagact
    11341 ccaaaaccca gctgaaaaat cggtcatatt ccttaaggta ttcgtacagg gttgtaaaac
    11401 tgtagggcac agccagctta gattggtagt attccagaac ataccagggc atgagttgtt
    11461 ttagtttgtc gattcgttcc agtaaaatct cacgtttcat gtattttctc cataagtaag
    11521 tatactagta gtatagcata gacttgtata tttttcaaga aaattatagt ttttcagaaa
    11581 gatgttatag gagtttttca aagtgataaa aagacttaga cctacaaaca aaacagaata
    11641 aggaaaataa taaaaatctc acccactaaa cttctgttaa tactacatag ctagaaattg
    11701 gtttgattgt cctgattgtt ttatcctatt tctatttcat ttcactatat aattgctatt
    11761 gttttctttt tcatgatttt aatcttactg tacagatt
//
LOCUS       DAVLZS010000053        11617 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLZS010000053 DAVLZS010000000
VERSION     DAVLZS010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.053"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            1..942
                     /locus_tag="VYO88_001689"
                     /pseudo
     CDS             1..942
                     /locus_tag="VYO88_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1070..2092)
                     /gene="cbpF"
                     /locus_tag="VYO88_001690"
     CDS             complement(1070..2092)
                     /gene="cbpF"
                     /locus_tag="VYO88_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEV1719746.1"
                     /translation="MKLLKKMMQVVLATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGALKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKPAPWYYLDPATGI
                     MQTGWQHLGNKWYYLRSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(2111..2932)
                     /gene="cbpG"
                     /locus_tag="VYO88_001691"
     CDS             complement(2111..2932)
                     /gene="cbpG"
                     /locus_tag="VYO88_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV1719747.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGNWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(3013..3252)
                     /locus_tag="VYO88_001692"
     CDS             complement(3013..3252)
                     /locus_tag="VYO88_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719748.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3402..3668)
                     /locus_tag="VYO88_001693"
                     /pseudo
     CDS             complement(3402..3668)
                     /locus_tag="VYO88_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3693..4004)
                     /locus_tag="VYO88_001694"
     CDS             complement(3693..4004)
                     /locus_tag="VYO88_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1719749.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYKHPELEEIILIFFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(3929..4160)
                     /locus_tag="VYO88_001695"
                     /pseudo
     CDS             complement(3929..4160)
                     /locus_tag="VYO88_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(4161..4793)
                     /locus_tag="VYO88_001696"
     CDS             complement(4161..4793)
                     /locus_tag="VYO88_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719750.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            complement(4807..5802)
                     /locus_tag="VYO88_001697"
     CDS             complement(4807..5802)
                     /locus_tag="VYO88_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1719751.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5799..6497)
                     /locus_tag="VYO88_001698"
     CDS             complement(5799..6497)
                     /locus_tag="VYO88_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1719752.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6575..7585)
                     /locus_tag="VYO88_001699"
     CDS             complement(6575..7585)
                     /locus_tag="VYO88_001699"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1719753.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(7569..8576)
                     /locus_tag="VYO88_001700"
     CDS             complement(7569..8576)
                     /locus_tag="VYO88_001700"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1719754.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8563..9516)
                     /gene="mvaD"
                     /locus_tag="VYO88_001701"
     CDS             complement(8563..9516)
                     /gene="mvaD"
                     /locus_tag="VYO88_001701"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1719755.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(9498..10376)
                     /gene="mvk"
                     /locus_tag="VYO88_001702"
     CDS             complement(9498..10376)
                     /gene="mvk"
                     /locus_tag="VYO88_001702"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1719756.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10498..11517)
                     /gene="cbpC"
                     /locus_tag="VYO88_001703"
     CDS             complement(10498..11517)
                     /gene="cbpC"
                     /locus_tag="VYO88_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1719757.1"
                     /translation="MKLLKKMMPIALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIHGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPISEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVQ"
BASE COUNT         3438 a         2688 c         2036 g         3455 t
ORIGIN      
        1 cagaaaatga gtacctgaga gcggagaatg ccatcctaaa aaagttaaga gaactccgat
       61 tgaaggagga aaaagagaaa gaagaaagac agaaattgtt caagaattaa tgactgagtt
      121 ttcgttagat cttcttctaa aatccattaa actagctcgt tcgacctact actatcactt
      181 gaaacagcta gacaaaacag ataaggacca agagcttaaa gctgaaattc aatccatttt
      241 tatcgaacac aagagaaatt atgcttatcg tcggatttat ttagaactaa gaaatcgtgc
      301 ttatctggta aatcataaaa gagttcaaca cttgatgaag tactcaattt acaagctaaa
      361 acgcgacaga aacgaaaata ttcttctcat aaaggagacg ttggcaagaa ggcagagaat
      421 ctcattcaag gccaatttga aggctctaaa acaatggaac agtgctacac agatgtgact
      481 gaatttgcca ttccagtaag tactcaaaag ctttacttat caccagtttt agatggcttt
      541 aacagcgaaa ttatcgccta taatctttct tgttcgccta atttagaaca agtacaaaca
      601 atgttggaac aggcattcac agagaagcac tacgagaata cgattctcca tagtgaccaa
      661 ggctggcaat atcaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
      721 tccatgtcac gtaagggtaa cagcccagac aatggtatga tggagtcctt ctttgggatt
      781 ctgaaatcgg aaatgtttta cggttatgag aagtcgtttc agtcgcttaa gcaattggaa
      841 caagctattg tagactatgt tgattactac aacaataaac gaattaaggt aaaactaaaa
      901 ggacttagcc ctgtgcaata cagaactaaa tccttcggat aaattaattg tctaactgtt
      961 tgggggcagt acagaaaaac cttgatacta tgcgtttttt gattgtgaag acttttatcc
     1021 acctattata caaagttaag tatccatcac agtttacaat tagccttcat tacttaaccc
     1081 attcaccatt atagtttaag tagtaaccac ctactgtggt attaacagct aaagcacctg
     1141 aatcataggc atagtaccag ttaccattga cttggaacca gcctgttttc atatctccat
     1201 tacttgcatt tagatagtac caagtcgaac cttcctgata ccaaccagtt gccatagctc
     1261 ctgatgaacg gagatagtac catttgttcc caaggttttg ccagccagtt ctcatatcac
     1321 cattttcagc atctagatag taccaagttg agccttcctt ataccagcca gttgccatag
     1381 ctcctgatga acggagatag taccatttat taccaagatg ttgccaacct gtttgcatga
     1441 tgccagttgc tggatctagg tagtaccatg gagcaggttt tagcttctct tcatcatacg
     1501 taagagggta atccttaacc caaccacgtg ctagctctcc aaccgtcaat ctgttgatgc
     1561 gagaatcaaa gccaccatcc ttctgtaaat aataccaatg accctcttca taaatccaac
     1621 cagtttttaa agtatgataa ctacgctgat cttcaaaata atagactcgt ttctctgctt
     1681 ggctatcata ttcttcccca tgatgtttgt tggtattcgt agcagttttt gcttctaaaa
     1741 cttgcttgcc aacaaattct tgtaagacac catcttgacc aaaataaaac caatctggtc
     1801 taagagcaat ctctattctt ggagaaggac caatcgtaac ccccttgtgt ggagcaggta
     1861 tatattgcca gccgacaacc atctctccgg ataaaggatc aaaataatag tacttcccat
     1921 ctatcactct ccagtaggtt tcttttagag cccccttttt gtagtaggtt ctaccatttt
     1981 cttggacaaa ctgccatcct tcagaatcat ctgcaaatac tgtactggtc cctagcaaac
     2041 cgaagaaaaa tgtggctagt acgacttgca tcattttttt caaaagcttc attttatata
     2101 tcctccaaca ttaaatccac tcaccagatg aagcgaagtt ataaacttta ccatcgatag
     2161 tttggctacc tgtaaccatt gctccatttg aattgagata ataccagttt ccatttactt
     2221 tttgccaatc tgtaagcatc ttaccggaac tgtctaaata ataccaagta tcatttatct
     2281 cctgccaacc cgtttgttta tcatgttgtc tataatggta ccaactacca tttattttct
     2341 tccatccttc aagagagtaa cctttaagaa ccgaataaat aaatggcaaa tttcgttcat
     2401 ttaatttaac tgcactgtta atttgattag ctccatctcc taaagtatgc actcctacta
     2461 cacggtgact agcatcataa actgtagatc cactagaccc ctctaaagta tcaacttggt
     2521 aatccaagaa catgccatca tcacttaaaa cttgtttttt atctgtatac atttgatgaa
     2581 ttttaaaatt atatgatgga tagcctgtga tagtcacagt tattcctgtc aaattttttt
     2641 gactagtagg aagacccaaa gtccctaatt ttgcaccaat gggctcttct agaattaata
     2701 aagccaagtc atattccctt gcatccttag aatttaaatt tctaaattcc ttcaaataac
     2761 gaacttcctt tactttgatc tttccaaata gttcttgact tggactaaca gccggaagaa
     2821 cataaatatc atccgcttct ttcccatagt catgtctgta gtagttgtga gccgctgtaa
     2881 ttaacacatt atctttaata aaattcgcac ttcccctccc ttctacattc attccatcgg
     2941 ctactccata atacttagat aaaaccatag ctgaagtcga atacggatac tgtaaagtat
     3001 tatcaatttt aatcaaatca tcattaccga taatacttct gattgctttt ggtagtatga
     3061 accatacgtt ggtgaaatct cagataatga agaatcatta gaccctggac ctttttctag
     3121 tgtctcactt acctcatatt cttcacctgt actagaaata acactcaaag cagatactgt
     3181 cgataactgg ctagccaata aagtactcgc aataattgaa atacccaatt ttttataaac
     3241 agttttcttc attatcgtat cctcctaatg taattatagt gtactattct aaatttctca
     3301 atctactata gaatcaagaa atctaccacc ttctttaaat accctccatt atcacataaa
     3361 caggtaaact tttcaattaa tgactgcgct tttcaatcac gctagaggta cttgcttgct
     3421 tctttgatac taagttcagc cattctttcc ttgtttttct caataaagca tgttacccaa
     3481 gtgggattcg ttttggagta gtctcgcaga gtccagccaa tggctttatt gataaaaaat
     3541 tctgtttggt tcaagttatg aaggagaatc ttttccatta attgagtatt ggtcttctct
     3601 tttcttaaca actggtggtc aatagcgaca cgtctcagcc aaatattatc taataggctc
     3661 cattttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag attgctcaaa
     3721 acactgtttt gaggttgcag atagagctga cgtggtttga agagattttc gaagaatatt
     3781 aagattattt cttctagttc agggtgttta tacaccaaac tccctactac tcgatctagg
     3841 atatctaccg tgtcccacca ggattttgtc acgactaact gctctagctt aggcaaatcg
     3901 gtttccttta gataagactg cattgctttc aaatagttag cagccacata ttggtatttt
     3961 ctaggctcct tttcccagca agtgtctgca aaatcccaat cgataatctt tgtttttttc
     4021 gcttctggaa aatattttta tagagtttat ttctttcaac ctagaaaaga aaattgatgg
     4081 cacatatagg cttccatggg ccttgctttt ttagagtctt ttgctgcttc tagctcctca
     4141 agtaaatctg ctaaactcat ctaaaactcc tcatgcccga ccaaatggtg ctgaaaggca
     4201 tagacagccg cctgggtacg atcgctaact tcaagtttgg caagaatgtt ggacacgtgg
     4261 gtcttgaccg tcttgagaga gataaagagg tcatctgcga tgcgctgatt ttcgtagccc
     4321 ttggcgatga gttggagaac atctcgctca cgcgcagtca attcttcatg aagttccata
     4381 tgattgcggt ggtattcaac cttcttgcta acctcttgct caatggccag ctcgccagca
     4441 gctaccttac tgacggcatg aagcaattca tctgcactag aagtcttgag catatagcct
     4501 ttggcaccag catctaagac tggcatgatt ttttcattgt ccaaataaga ggtcacaatc
     4561 aaaatcttgg cttcaggcca ttctttaagg attgctaagg tcgcatcaat cccattcatc
     4621 tcaggcatga caatatccat gacaatgaca tctggacgca gttccaaggc caagtcaatc
     4681 ccttgagacc cgttggacgc ctcacccaca acttctacat cgtcttggag gtcaaagtag
     4741 cttttcaagc ccaatcggac catttcatgg tcatctacta gtaaaatttt catctttact
     4801 cctttatcat tccttatcta acaggggaat acggatatca accgccagcc cttgcttggg
     4861 agctgtcaag agttgaactg ttccagccat atcttcaacc cgctccttga tatttcgcag
     4921 tccataactc aagtcgtcta agctccctaa ctggaaacca atcccattgt ccaccacctt
     4981 cagttgcaat tcaacatctg tctgatagag gtagacatct aggcaagatg cctgggcatg
     5041 gcggagggta ttgctaatca actcttgcag gatacggaag atatgctcct cgattttctt
     5101 aggcaatttc gtcatattct gcttgagact aaccctaaga tcactcttgt cctcaagctc
     5161 ttttaagaga atttgaatcc cttctatcaa gctcttctgc tccagttcaa ctggtcgcaa
     5221 atgcaagagc aaaacccgca aatccttctg ggcagtttct aaaatagctg tgacactctg
     5281 caactgggtt tgcatctttt ctctatccaa tttcaaagcc tgctgactga tacccgataa
     5341 aatcatgtgg gccgcaaaca actcctgact gactgtatcg tgcaaatccc gagcaattcg
     5401 cttccgttcc ttctcgatga tttcctcttc ctgagcaagg ctctgatttt cagctttttg
     5461 aagagcctct gtcaaaaggt taagtttacc tgataaggac ttgaaactgg catccaaatc
     5521 tggatctaca acctgaacta cttcttgccc tgccaataaa cgcttgagat tagcctgcat
     5581 ttttcttaga gaaagctctt cgatccctcg ccaaaacagg gctaagagac aggtcatgga
     5641 catgctgaaa accaacaata aaaagacaaa tttttctgtt ttttcgacat cgtgcaaaaa
     5701 gatagaccag tcaaaatcaa gtatttccag caagctatgg gagaaaaaaa agacaaacag
     5761 gaaggaggtg agagcgataa tgacataggc ttgttttttc atcctctaac cacctccaca
     5821 tcaccaatca tagtggtcaa gaaaatcttg acactcttgt tactcttgag atagtctttt
     5881 gtttcttgat gatagtgttc attgcggagg gctcgcttgg gctggttgaa aaaagtcaaa
     5941 tccccataga gacagttaac gctgagactg acttccacat ctacaggtac gatgattttg
     6001 gtcgttccta ccatctttct gaggataatg acattgtcat gattggttaa gatgaccctc
     6061 tccagatgaa tagtgtcctt gcccatgaag cgaaagagat tgatatcatc gaattggcaa
     6121 gtctggtagc ttgaaaaatg atgaagattt ccaaaccaac gatttttctc cttcttaacc
     6181 gtcacgacct cttcaaaaac caaattggtc tgctcttttt cctggttcat catcgggtaa
     6241 agaagaaaga ggctatagat aaccgcaaca aaaatagcta gaatcacaaa aggattgagc
     6301 ataacgatga aaaagaagag aatggttgcc gctactaaaa gaagattatt tccctcttta
     6361 ccagtgtagt agcgaatcaa aagcaaaaag aggaatagta tcagcagaaa acgcgaaaaa
     6421 tgctctgata ccatcaaaat cagagctcct gtcagaagac aggcttcgat aaataaaaag
     6481 attttaaatt ttctcatagg ttcatcctct cccttctatt ttatcacaat tcaaaaaagt
     6541 cacctcagtc tgaggatgga aaaaaaggcg ctggttacgc ctttttcatc tgatcatttg
     6601 cttcttttaa ttttccataa agaagatagt ctactttttg tagatctgct atggtggcac
     6661 agttaaggga acacataatc aagcgtagat ctgctttcca gccttggaca atgccaatca
     6721 cttcttcaac tgtgtaggtt tcaaccaatt ccagaacggt tcgtgacaat cccacagcct
     6781 tagcaccaaa aaccaagcac ttaatcatat ccagcggatt ccgaacccct ccactaacca
     6841 agagttcgac cttatctttc cattcttggg cattgagaag ggcctgcatg gtagactgac
     6901 cccattgatt gaggtaatca cgctggccac tacgacggtt ttcgatatag gcaaagctgg
     6961 tgccaccacg acccgatagg tccactgtac gaacaccgaa ttcataggct ctttcgattg
     7021 tcttggcatc cattccaaag cccacttcct tgaggacaat aggaacggga atttgcttgc
     7081 tataatctgc tagatgcgat tgccagcttc taaacttcct ttctccctcg ggcatgagta
     7141 attcctgcat gacattgaca tgcacttgca atagaacagg attcatctct tctacagtct
     7201 gaagtcctaa ctcgacaggc ttgtccaatc caatattggt tccaaggagg agattgggat
     7261 gactagactt gacagaaaaa gaatcatccg ttggattttt gagggctgcg ctataagaac
     7321 ccgttacaaa taaaatacca caggattccg ccacctgagc cagcttttga ttgatttctc
     7381 ttcccttatt acttccacca gtcatggcat tgatataaaa aggaaagtcc cactttcgac
     7441 cagcaaactc tgtcgaaaga tcgatttcat ccagattgta aagaggcaag gaagaatgaa
     7501 tcagctccac ctcatcaaag ctattatagg aacttttctg ctcaagggca tagaggatat
     7561 gctcgtcctt acgatttgtc gtcatgtcct atcctttctt gatataagag ctcaatcccc
     7621 agatcggccc aacgattttt taaggttttg gttgattgcg catcaaaact cagggcgatg
     7681 ccacagtcac caccaccagc accactactc ttggcaacgg cctgcaaatc ttgactggct
     7741 tctttcaact gtctaagcaa aggcgtgtaa atatctgtac tcaagccttc taaaagcttg
     7801 ctggctactt ctacttgctc gataatcttt tctgatttcc cctgttccaa ggcttcgacc
     7861 aaagaaacca ccgtttcttt tgaggaactt aaaaaatttt gattgatatt ttgcttgatt
     7921 tgctggacca tgtgactcga tacagccact tccttggtcc atcccactaa gaaatcacat
     7981 tctaaagttg gtttcacttg tgaaattgaa aagccccaat cacgctccag aactgtcgcc
     8041 aagttttctt cttctaacca agcagccacc ttctggcgat caaatgactg gtagagaacc
     8101 aaatcctctg ccacaataca ggcaaggtcg cccatggaac cattgtctcc tcgcttgagc
     8161 aagacagcgc tagtcagctt gaacaagagc tcctgatcaa cagaaacatc atacagagcc
     8221 agtaaagcct tgacaaccaa gacaacgacg ctgccactag aacctagacc aaactttttc
     8281 ccttctcgtt ccattttgcc acagatttct agagaaaaag gtcttaaatt ctgaccacga
     8341 acagcgagga agtctcccat caaagcaatc gtttcttgaa tcaagctgta gtcaggatta
     8401 ggccttaagt ccactgcgaa atcaaacata tctgaataga tacggtagct gtcagaaaaa
     8461 gcaatctcag ccctcatata gatgggaata tcctttatca aagctaactg ccctggctct
     8521 aaaatagcat attcacctgc ccaatagagt tttccgcaag ttttaacagc aatcatcttg
     8581 actcaaatcc tttgtttttg acacaatcaa gcgataacga tgaccgaaaa tttctgataa
     8641 atgctccaag tctttctcct gacagaagac cttaacattg ggaccagcat ccatggtaaa
     8701 gtagcaggcc tctcctttct cacgaagctg gcgaacaaag tccatagcct cataagaggc
     8761 atccgtcaga taagaaaagg ctggactagc agtctttgtc gtagcatgca tagccagggc
     8821 atttttctcc gttaattctc caatcttggc aaaatcattt tccttgagat aaatcagcat
     8881 atcctgatag tccttctcag actgacgaac ccagtcgtca aaagtcgtcg aggtttccac
     8941 acaaagtttc atcccgtcac ggctagagat tggttttttc ttgtcctcta gcaccaacat
     9001 aatcatagct agtttcaagt ctgtctctac agggtaaatt tctccactat ccttatccca
     9061 ggctcctagt ggtccataaa aactccgaga agaagaacct gaggcaaatt tggcttcctg
     9121 tgccaactga cttctatcca atccaagctt gaaataagca ttacaagcct tgaccagggc
     9181 ggacaaacca ctagaacttg aggacagacc cgctgccgta ggcatattgt tttgagtatc
     9241 gatacggaca aagccctcac cagctggacg ataacggtca ataatcttac tcatcttggc
     9301 atgctcgacc tcattttgta gctgaccatt gatgtaaaat tcgtcagctg ttacattggc
     9361 tggtaaaggc gacaaggtcg tctctgtata catattttcc aaagttagag aaatactgct
     9421 agtagcaggc accatctctt tttctttttt ctttccccaa tatttgataa tagcaatatt
     9481 tgcgtaggaa cgtactgtta caggctctct atccatgtct gaacagctcc tttctcttct
     9541 aatctttctg ctagttcttg tgcgtgtgtc aaattggtta ccaaggctat gatacaacct
     9601 cctagcccac caccgctcat cttggcaccc agagcaccat ggctaagagt cgtttcaacc
     9661 aaaaagtctg cctcagggct actgactcca atttctttta aatgtaaatg cgcttgactg
     9721 aggatttgtc ccagtccttc agcatctttt tgtgaaatcg caacttctgc ttgctgggtt
     9781 aattctccca aggcatgcaa aaacggtagg gcatccttgc ccttattttg aaccacttgg
     9841 atggcttcac gagtatgacc ataaacaccc gtatcggcaa tcaccaaata ggcggataaa
     9901 tccatctcaa gttctgtaaa tcctacgttc ttgataaagc gaataggttg gtcactaaga
     9961 caggtcttag catccaaacc actaggattc atatgggcaa tcatttcagc tcgattgacc
    10021 aagatttcta gtacatcatg aggcagatca gcctgatagt agtcaaatac tgcacgaatg
    10081 gccgctatgc tgatagccgc tgacgaaccc atcccccgtt tctcagggat agccgagtca
    10141 atctcacaac gaatgcaggc ttctgtgata ttcaaatact ccagtgaggc ataaaccgcc
    10201 atggacaagg tatcctcctc ataaaggcgc caaggactct ctgcaggaac taccttacag
    10261 gtcacctcca cctccaaaag aggcagggaa atggcaggat aaccgtaaac gaccgcatgt
    10321 tcccctatta aaattatctt actatgtgcc tgaccgacac caactttttt tgtcattttt
    10381 tccttttact agacgaaaaa acgtcttatt tttcatacaa gtattaattc tttcctatct
    10441 attttattat attttcacaa aaaaagcgat tgtttccatt cacaatcgct tctttcatta
    10501 ttgaacccat tcgccattat agttgacaga atagccatct acggtcgtat tcactgccaa
    10561 ggcacctgag ctataagcgt agtaccatct gccattgacc tggaaccaac ctgtcttcat
    10621 gtctccatta cctgcattta ggtagtacca agttgaacca tcttgatacc aaccagttgc
    10681 catagctcct gatgaacgga gatagtacca tttgttccca aggttttgcc aacctgtttt
    10741 catatcgcca tttggctggt ctaaataata ccaagtggta ccttcctgat accagccagt
    10801 ggccattgct cctgatgaac ggaggtagta ccagttatta cctagatatt gccatcctgt
    10861 tcgcataatg ccagtttctg ggtctaggta gtaccatgga gcaggtttgc ttctatcaat
    10921 gtcaatagta acatgaaaat cttgagtcca acccttagca acttcactaa ttggtagtgg
    10981 attgtaagaa tcatcgccaa aatttcctag cttatttaaa taataccaat tgccgtcttc
    11041 ataaatccag cctgtcttta cagcataatt attatcaaaa taataagttc tcttttcagc
    11101 agatagagga tattgttcac cgtatacttt tcctgtattt tcagacgttt ttgcctctag
    11161 tacttgttta tctgtttgtt ctagcaaagc accatcttgt ccaaaatagt accacttctc
    11221 ctgaaggcca atttcgaaga ctggacgatt atcaaataaa tcatcacgat aacctgttcc
    11281 atgaatttct aagtattgcc aaccgacaac catctctcca atatcaccaa aatagtaagt
    11341 tttaccgtct attttatgcc aatagattgc tttatggtca tcttttacat aatattttct
    11401 attatcctta tcaacaaatc ggccacctgt ggtattcgca aataccgtat ttgtcgctag
    11461 caaaccaaag aaaaagacgg ctaatgcgat tggcatcatt tttttcaaaa gcttcatcta
    11521 tatatcctcc taaaacgatt gtagtaaaaa ctagattgta tgtcaatata taaaaactcc
    11581 tcaaaaaagc agttacacaa ctgcaactgc ttttcta
//
LOCUS       DAVLZS010000054        11583 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLZS010000054 DAVLZS010000000
VERSION     DAVLZS010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.054"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            362..949
                     /locus_tag="VYO88_001704"
     CDS             362..949
                     /locus_tag="VYO88_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719758.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQKKWMFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(1036..1239)
                     /locus_tag="VYO88_001705"
     CDS             complement(1036..1239)
                     /locus_tag="VYO88_001705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719759.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(1536..2240)
                     /locus_tag="VYO88_001706"
     CDS             complement(1536..2240)
                     /locus_tag="VYO88_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1719760.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(2310..4136)
                     /gene="glpO"
                     /locus_tag="VYO88_001707"
     CDS             complement(2310..4136)
                     /gene="glpO"
                     /locus_tag="VYO88_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1719761.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(4178..5686)
                     /gene="glpK"
                     /locus_tag="VYO88_001708"
     CDS             complement(4178..5686)
                     /gene="glpK"
                     /locus_tag="VYO88_001708"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1719762.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(5845..7272)
                     /locus_tag="VYO88_001709"
     CDS             complement(5845..7272)
                     /locus_tag="VYO88_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1719763.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            7437..8309
                     /gene="hslO"
                     /locus_tag="VYO88_001710"
     CDS             7437..8309
                     /gene="hslO"
                     /locus_tag="VYO88_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1719764.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            8296..9276
                     /gene="dusB"
                     /locus_tag="VYO88_001711"
     CDS             8296..9276
                     /gene="dusB"
                     /locus_tag="VYO88_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1719765.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(9506..11521)
                     /gene="cbpA"
                     /locus_tag="VYO88_001712"
     CDS             complement(9506..11521)
                     /gene="cbpA"
                     /locus_tag="VYO88_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpA"
                     /protein_id="HEV1719766.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLVMGSVVHATEKEGTT
                     QVATSSNMAKTEHRKAAEQFDEYINKMIQLDRRKDIQNRTLIIKLSAIKTEYLRELNV
                     LEYKSKAELPSKIKAKLDAAFDQFKKDTLPTEPEKKVAEAEKKVEEAEKKAKAQKEED
                     RRNYPTNTYKTLELEIAEFDVEVKKAELELVKEEAKKPLNEGTIKQAKEKVESKKAEA
                     TRLENIKTDRKKAEEEAKRKADAKEQDESKRRTKRAVPGELATPDKKENDAKSSDSSV
                     GEETLPSPSLKSGKKVAEAEKKVEEAEKKAKAQKEEDRRNYPTNTYKTLELEIAESDV
                     EVKKAELELVKEEAKGSRNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAEEAKRKVA
                     EEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEE
                     YNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSN
                     GAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLN
                     ANGSMATGWLQNNGSWYYLNANGSMVTGWLQYNGSWYYLNANGSMATDWVKDGDTWYY
                     LEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
BASE COUNT         3127 a         2620 c         2262 g         3574 t
ORIGIN      
        1 atacgtctat ttatttttta ttgtttttta ttgtagagca gacccaagcg aatgaacata
       61 ggttgtaaaa agcaaatgaa aaaactgcga ggataatagc ttctgtgtct aaataaccca
      121 tttcgagacc tcttttcaac aacaacaagc ctgtagtttc gataacgatc aaacataaaa
      181 atatataaaa aattttcgca ttaagcatat tgttaccgct ttctttttat ttggttttat
      241 tgtataataa aagttgaaaa aaatcaaaaa tacaaaggag tttccgttat gtctaagatg
      301 tttaaatgca tgtgtttgct agttatgtct gttttctgta tgtctagcat ttccccgtcg
      361 cttgtttgtt tttgctgatg atagcttatc ggcaaactct aaagttgtat ctggtgaggc
      421 tcagtttgag aatggctcat cagtgcggtt cggagatacg caagtaaata ttttaagcga
      481 tgaagttctt gaggttgtca atccagatgg aagtgtagac actattgaac gacgtgctga
      541 cggcgtctat atcaatgggg cattttatat ggcttatcaa aagaatgaaa tcgacctaaa
      601 tatatctttt agatcatacg atcctaatgt ttggaattac gtcaacacaa tacatgggaa
      661 taaacaagct aacacattcg ctaacttcat gactggtgct ggaatcagtt atatgattgg
      721 taggataggt gctttattgg ggggtccatg gggtgcaata attggtggag catattttgg
      781 tatacaagct tatcagtctt acttggattc acaaagccca tatccatact acataacaag
      841 tacttatatc catgttgctc aaaaaaaatg gatgtttatc actgaatact atagaaactc
      901 aaactatact gggtatgtaa aaaccgtaac aacctacgtg aatttctaaa atataaaccc
      961 tgcctagata taaaggcagg gtttatattt tagttaattg ctcaagtaat ttgtaagcat
     1021 aatacttgcg aaactctatt tgttcaagcg gttcaaaagc tcttgttttt tatcctcaag
     1081 ctcagctctc ctttgctcga tttcttcacg tttttgggcg atttctgctt gcgcctcggg
     1141 agtttccaaa gtgccttgtg acttgtgaaa ttctactagc atatcaacga tttttgggtc
     1201 taattcgttg acataatcag gatttgacca tttcggcacg ttgcttgcag gtgcttgctt
     1261 tttgccgcct tttttgggcg ttttggcttg ttgttcagct ttctgactgt agttgacctc
     1321 gtggaatttt cgtgcttgat atgatgcgtt ttattatgag aagatttact tcattttttg
     1381 ctgaaattgg gctcttgccc aagctctatc aacataattg ttttctaata ctcaatgaaa
     1441 atcaaagagc aaactaggaa gctagccgca agctgtactt gagtacggta aggcgacgct
     1501 gacgtggttt gaatttgatt ttcgaagagt ataaactaga aaagtgagaa tacaagcact
     1561 gccaaggctg ctccgataac agggcctaca acaggaatcc aagcgtaaga ccagtctccg
     1621 tctcccttgt ttggaattgg caagatgctg tgcatgatac gaggtccaag gtcacgagct
     1681 gggttcaagg cataacctgt tgtcccacct agtgatagac cgataccgac aatcaaagtt
     1741 cccactgcaa aggttccgat acctgcctga aaatcgtaaa gacccaaagc aaagattgtc
     1801 aacaccaaaa caaaggttcc aaggatttcg ctaatcaagt ttgatacagt atccttgatg
     1861 gctggtccag tactgaaggt tgccaggata ttgcctgcat tttcttctgc ctcatagtga
     1921 ggtttgaatt gcaaccaaac caaaatctga cccagcatgg cccctgcgaa ctgggctaag
     1981 atataaggca aaacggaagc ccaaggcaaa ccacctttta aggccacacc gatggtcaca
     2041 gctgggttta aataagctgg actgagcttg ccagatacaa agactgcaac cgcaactgca
     2101 atcccccaac ccatagtaat cacaatccaa cctgagctat tgctcttggt tttaggaaga
     2161 accacacctg caacaacacc atttcctaga agaatcagga ttaaagtccc tagaaattct
     2221 ccaaataatt cattcatcat ctttctgtct ccattaaaaa gaagggacgg gcgacaagga
     2281 atgctgccct ccacctcttt tattttttct taatttttta attctgctaa atcgttgtta
     2341 gcgagagctg cttcgacatc agcacggtaa gttgcttttt cttcttctgt ccagtcatag
     2401 aatcgtccca tttcatccaa aattggctca acgatactat ccaagctatc acgcataaag
     2461 agcatgtgat tggtacgacg aagaaggaag tcaactgggc taagagtcaa ctcattgcgc
     2521 attgcatagt gaagggacaa ggtgtctgcc aagctaagac ctggcgcttg ttccaagctg
     2581 tgagcaagtg caaagacctt cggtgcattt gaaccgtaaa gatttgctag gtaatgagct
     2641 tccttgctat ccaaaccacg tgaaactcca agttgcgcaa aggcttcgat ttctgaatcc
     2701 acatttgctg ggttcaattc tccacctgaa acagggtaag ttttagaatt gatcaattta
     2761 aagctacggt caaattctgc tttgaggatg tcaaccacgc gctccatagc tccttcagcc
     2821 atcttacggt agtctgtgat tttaccacca gcaagagtca agagaccatt gtcatcacgg
     2881 tccaagctag acccacgaga aactgcagat ggatccaaat gtttctcaga tgtgctactt
     2941 tcaagcttgc tgacagcaga ctcaacatct tcacgtgttt tttctttgga gagataagat
     3001 tcaacagtcg caatcaagtt gtcaaagctt tcatcactga tggtaccgtt atttccacca
     3061 ttatagtcag aggcactgtt ccctgcaatc aatggacgaa gacctgccca gctgctttcg
     3121 atatcatcaa tggtgatgtt ggattctggg aagcggttgt tgacaatgcc aagtagataa
     3181 tctacatctt cttgagttac ttttggatgc tccaaatcac ctgtgtagtc tgtatcagtt
     3241 gtaccaaagt aagtcttgtt ttcacgtggg agaacaaaga ccatacgacc gtcacccaaa
     3301 cctgtgtcga agtaaactgg ctgtgaaacc ttgattttac ttgaatccac taccaagtga
     3361 actcccttag ttgggcgcat ttgtgagaat tgcgttccct tattagacaa attacgtact
     3421 ttatcactcc aaggacctgt tgtattaata accagacggg ccttgatttc aaatacttgg
     3481 tctgtcaaga gatcacgagc tacaacacct gtaatcttgc cactttcgtc aaagaggaag
     3541 ccttctgcct tcacgtggtt ggcaatgagg gcaccgtctt ggttggcacg tttgatgttt
     3601 tcaatcacga gacgcgcatc gttgttacgg aagtcaagat acactccacc tcctaccaag
     3661 ccttccttct tcaagtttgg ctggcgttcc aagacttctt tcttgctcaa aaccttgttc
     3721 gcagttggtg tgttgctcac acctgctaaa aggtcgtaca agtccatggc tactttaaga
     3781 cggaagaggc taaaggttgc tccatcttca tcgtaaactg gtaagagcat tggatctggt
     3841 tttggaatgt gtggagcgat ttgttgaacc actgcacgtt cagaaaccgt atctgagacc
     3901 acttctacgt cgaattgttt gaggtagcga agacctccgt gaaccaattt tgttgaacga
     3961 ctagatgttc cttctgcaaa gtcttgcatt tcaatcaaac cagtctcaag accgctagct
     4021 gccgcctgca aggctacacc agctcctgtg attcctccac cgataatcaa gaggtccagg
     4081 gtgcgttcct gcattttttt aattgacaat tcacgtgttt tctttgaaaa ttccatattt
     4141 acacactttc taaataaatc gctttattct gccagtatta gtcgtctact tccgcaaaga
     4201 cttgagttgc tttcacagcc ttcttccagc ccttgtagag ttgttccttg cgagattcat
     4261 tcatagatgg ctcaaagagt tctcctgtct cgttcaagag tttcaactcg tccaagtctt
     4321 tccagtaccc tactgataaa cctgctagga aggccgctcc tagagctgtt gtttccaagt
     4381 ttttagcacg tgcaatatca atgcctaaaa tatccgcctg gaactgcatg aggaagttgt
     4441 tcatggctgc accaccatcc accttcaata cttgaatggc agtctgagta tccacttgca
     4501 tggtgtcgat gatgtcacgc acttgataag caatagattg caaagtcgcc ttgataaagt
     4561 cttctttgct tgttccacga gtcaaaccaa agacggaacc acgagcattt tggttccagt
     4621 atggagcgcc tagacctgta aaggctggaa cgacataaac ttcatcgttg ttgtgagaat
     4681 cacgagcgta tttttcagat tctggtgaat tttcaaccat gcgaagaccg tcacgaagcc
     4741 actgaatagc acttcctgcg atgaagatag aaccttccaa ggcataataa accttaccgt
     4801 tgattccgta accaatggtt gtcaagaggt tgttttcaga caactgcatc tcttccccag
     4861 tattcatgat gatgaaagag cctgttccat aagtattctt aaccatacct ggctcaaaag
     4921 ccaactgtcc aaagagggct gcttgttggt ccccagccat acctgagatt ggcacctctc
     4981 caccgtagaa atggaatgga gctgttttgc cgtagatttc ggagttagaa cgaacttctg
     5041 gaagtatagc cttcggaatg ttaaggattt ccaaaatctc atcatcccat ttgagttctt
     5101 taatgttata aagcatggta cgagctgcat ttgagtagtc agtcacgtga gccgcaccgt
     5161 cagtcaattt ccaaaccaac caagtatcga tagtaccaaa gagcaattcc cctttttctg
     5221 ctcgctcttg agcgccttct acatgatcca aaatccaacg aaccttggta gcagagaagt
     5281 aagcatcaat aatcaaacca gtcttttcat ggaatttttc cacataacct tggcttttta
     5341 gttgctcagc caaaggtgct gtctggcgtg actgccaaac gatagcattg tagataggaa
     5401 gtcctgtttt cttatcccag acaaccgttg tttcacgttg gttggtaatc ccgattgcct
     5461 cgatttgatt tggcttgaca ccactttcga tgaaagcacc cgcaataact gactgaacag
     5521 agttccaaat ttcattggca ttgtgctcaa cccaacctgc ctgagggaaa atctgggtaa
     5581 actctttttg actcgagcta accttttccc cttttttgtt gaaaatgatg gcacgagaac
     5641 ttgtagttcc ctggtcaatg gccatgatgt atttttcttg tgacatgtac tgtcctcctg
     5701 ataaagatct tgaggtgttt cctctttaca cttactagta tacaaaataa agcgctttct
     5761 tgtttatcaa ctttttttaa tttttaaaaa aatgtgagga gattgtgtga atttcacaaa
     5821 aaagacctgg attaaccaag ccttttaagt gaataataac tgacgaatcc ctgccaaatc
     5881 ttccatatcc aagtcatttt ttaaataata gactggggtc tgttccttct tatgaatcgg
     5941 gttattggta accagcaaat cataatgccg actagggtca taagcttcaa tggtaataaa
     6001 acgattgtat tccaaatacc gtttcaaaat ggctgccatc cttgaaaaga caagaaaacc
     6061 agatgtcaaa tccagaccaa tccgcatatg ctggccaccg ttttcagcca tatattcgat
     6121 taactggagc cattcccaga gaatcttctt atctaaatct gtcccctgtt gaaaagcagg
     6181 tagagcatga aaaatctcct ctgctgtctc tttaaaatca tgttccatca gtaaatatgg
     6241 atgacgattc tctaactggt acttgtagcg atcctgtaaa atatagccct tatagagata
     6301 gacttgagca caaagctgac tgagttcata ggtgacatgg tcctctgtat aatcccccaa
     6361 tagttcctcc ttcttcattt cttgaatcaa ttgcgtcagt aaatctgcca actgccctcc
     6421 aaaaccaaga atatattcca tagtatgaag aggaagaatg cgatgagata ggagaaaaga
     6481 gaagaatatc atcatctcac catcctcaac tcctagtgga atatgttgcc cagcaaaaaa
     6541 ggacggaacc tttctcagca aacgaagata gaagatattg tcaaaatacc ctcgcatttt
     6601 ctcttctatg acttgaaact gacaagcatt gacccgaaga cgttgttgac tgatgtgagc
     6661 ccagagaacc aagtccaatt tctgccccac agacaaactt gcaccgcaga tttcctctaa
     6721 attggcaatc tcctgttttc tctctggttt ctgcatgtga ccttcccatt cctgactcga
     6781 ccagaccttt cggaaaagac agaaatagaa atagcgaatc tgatgctctg gacctcgcca
     6841 acgtccattt tggatggata aatcaaattc tgacaaaatc tgatttaaac cagccaagtg
     6901 acgaccaagc gtagcctcgc taatcaccaa ttcttgagcc agctgatggg ctaaaaactg
     6961 ttggtggtag agaagataaa ccaaaatctg gtatttaaca gcactctcca aaaacaagct
     7021 ccgaatatct ctccccttgg tagctgcacc gatagacaga cgcagatttt catcttctga
     7081 gtgaatagcc agctctaagc cactatccaa agccttgtca ttgagcaggg tgacatattt
     7141 ggttagggtt gcttttgaaa atcctgtttc ttccattaca gccttgacgg tcgtctgaga
     7201 ctcttgtaat agaaaggaaa ggattgaaaa ttgaccacac tcggctttct ccatcaaatc
     7261 tcctaaatac atttgttatc cctttcattt tctaccttaa gcatagcata aatctgacaa
     7321 atgctaaaat aatctgtttc tctttttatt ttcatgctga tttcctggtc cattatcctg
     7381 aaaatcagta aacacacggc tccccctttg ggcattttta tgctaaaata gtagctatgg
     7441 ataaaattat taaaactata tcagaaagcg gagcctttcg tgcttttgtc cttgatagca
     7501 ctgaaaccgt ccgcactgct caagaaaaac atcaaaccca agctagctca actgtagcgc
     7561 ttggtcgaac tcttatcgct agccagattc tcgcagccaa tgaaaaagga aataccaaac
     7621 ttacagttaa ggtgttggga tctagctctc taggtgctat tatcaccgtc gctgatacca
     7681 aggggaacgt caaaggctat gttcaaaatc ctggtgttga catcaaaaag actgcgactg
     7741 gtgaagtcct agtcggacct tttgttggaa atggtcaatt cctcgttatc acagactacg
     7801 gtactggaaa tccttacaac tctataactc ccctcatctc tggagaaatc ggtgaagacc
     7861 ttgcctttta ccttactgaa agccaacaaa cgccttcagc ggtcggcctc aatgtccttt
     7921 tggacgagga agacaaggtc aaggttgcag gtggtttcct agttcaagtc ttgccaggag
     7981 ccaagaaaga agagattgct cgctttgaaa aacgcatcca agaaatgcca gctatctcta
     8041 ctcttctcga aagcgacgac catatcgaag ccctcctcaa ggctatctac ggggacgaag
     8101 cctacaagcg tctttctgaa gaagaaatcc gtttccaatg tgactgtagc catgaacgct
     8161 ttatgaacgc tcttgccagc cttccaagct cagacttaca ggaaatgaaa gaggaagacc
     8221 acggggcaga aatcacttgt caattctgcc aaactactta caactttgat gaaaaggacc
     8281 tggaggaact cattcgtgac aaatcttaat acacctttta tgattggcaa tgttgagatt
     8341 cccaatcgta ccgttttagc gcctatggct ggcgtgacca actcagcctt tcgtaccatc
     8401 gcaaaagagc tcggagctgg actcgttgta atggaaatgg tctctgacaa gggaatccaa
     8461 tacaacaacg aaaaaaccct gcacatgctt catatcgatg agggcgaaaa ccctgtctct
     8521 atccaacttt ttggtagcga tgaagacagc ctagcacgcg cagcagaatt catccaagaa
     8581 aacaccaaga ccgatatcgt cgatatcaac atgggctgcc ctgtcaacaa aatcgtgaag
     8641 aacgaagctg gagctatgtg gctcaaggat cctgacaaga tttactccat catcaacaag
     8701 gtccagtctg tccttgatat cccacttact gtcaaaatgc gtactggctg ggcggaccca
     8761 tctcttgcag tagaaaatgc cctcgctgct gaagctgcag gtgtttctgc cctcgccatg
     8821 catggccgta cccgtgaaca aatgtatact ggccacgcag accttgagac cctttacaag
     8881 gttgcccaag ctctaaccaa gattccattc atcgccaacg gtgatatccg tactgtccaa
     8941 gaagccaagc aacgcatcga agaagttggt gctgacgcag tcatgattgg ccgagctgcc
     9001 atgggaaatc cttacctctt caaccaaatc aaccattact ttgaaacagg agaaatccta
     9061 cctgatttga cctttgaaga caagatgaag atcgcctacg aacacttgaa acgattgatt
     9121 aacctcaaag gagaaaacgt cgcagttcgt gaattccgcg gcctcgctcc tcactacctc
     9181 cgtggaacat ctggcgctgc caaactccgt ggagccattt cgcaagctag caccctggca
     9241 gagattgaag ccctcttgca attggagaag gcttaatagt ttaaaacccg taactctctt
     9301 aaagagcctc ttgaatgccg ccattctttc ctcatcaaaa aaactccgta gtctctagcg
     9361 ctataaatcc agctagagat tacagagtta ttttttaatc taaacttcct acaagggtat
     9421 attatctact gaaaggatat ggtatttgta gggaatactt taaagagttc ttacaggaag
     9481 tcagtattaa ctagttatat taggtttagt ttacccattc accattggca ttgactctat
     9541 agctatctac agttgtgttg actgcaaggg cacctgagcc attgacatag taccatttat
     9601 ctgatacttt gaaccattgg cttgctttca tagcacctga tgcttcaaga tagtaccagg
     9661 tatctccatc tttcacccaa tctgttgcca ttgaaccgtt agcgtttagg tagtaccatg
     9721 aaccattgta ttggagccat cctgtcacca ttgaaccatt agcgtttagg tagtaccatg
     9781 agccattgtt ttggagccat cctgttgcca ttgaaccatt agcgtttaga tagtaccatg
     9841 aaccattgtt ttggagccat cctgtcgcca tagcgccatt agcgttgagg tagtaccatg
     9901 aaccattgtt ttggagccat cctgttgcca ttgaaccatt agcgtttaga tagtaccatg
     9961 aaccattgtt ttggagccat cctgtcgcca tagcgccatt gctgttgagg tagtaccatg
    10021 agccattgtt ttggagccat cctgtcgcca ttgaaccatc agtattgtag aagtaccaca
    10081 taccgttttc ttgtttccag cctgtttttg gagtagatgg ttgtgctggt ttttcagttt
    10141 ttggcggttg ctgttgagtc aagcgattat attcttcttc tgatctacga gcatagtctt
    10201 cttcagcttg ttgatcagct ggtttttctg cttttggttg ttcagctgga ttctctggtt
    10261 ttggagctgg agctggtttt tctggttgag gagccggcgc tggttgtggt tgttcagctg
    10321 gtttttcttt aactttatct tcttctgcta cttttcgttt agcttcttct gcttttttac
    10381 gatctgtctt gattttttct aaccttgtag cctcagcttt tttactctca acttccgctt
    10441 ttgcttgctt aactttttcc tcgtttcgag atcccttagc ttcctctttt actagttcaa
    10501 gctccgcttt tttaacttcc acatcggact cagcaatttc aagttcaagc gttttgtaag
    10561 tattggttgg gtagttacgg cgatcttctt ctttttgagc cttggctttt ttctcagctt
    10621 cttcaacctt cttctcagct tctgctacct tttttcctga tttcagggat gggcttggaa
    10681 gagtttcttc acctacgcta gaatctgaag acttcgcatc attttctttt ttatcaggtg
    10741 ttgctagctc tccaggaact gctcgttttg tccgcctctt tgattcatct tgctctttag
    10801 catctgcttt tcgtttagct tcttcttctg cttttttacg atctgtcttg atgttttcta
    10861 accttgtagc ctcagctttt ttactctcaa ctttctcttt tgcttgctta attgtgccct
    10921 cgtttaaagg tttcttagct tcctctttta ctagttcaag ctccgctttt ttaacttcca
    10981 catcgaactc agcaatttca agttcaagcg ttttgtaagt attggttggg tagttacggc
    11041 gatcttcttc tttttgagcc ttggcttttt tctcagcttc ttcaaccttc ttctcagctt
    11101 ctgctacttt tttttctggt tctgttggta atgtatcttt tttaaactga tcaaaagctg
    11161 cgtctaactt tgcttttatt tttgacggca actcagcttt cgacttatat tctaaaacat
    11221 ttaattcacg caaatactcc gttttaattg cgctcaactt tatgattaag gtgcgatttt
    11281 ggatatcttt tcttctatct aattggatca ttttgtttat atattcatcg aattgttcag
    11341 cagctttcct atgttctgtc tttgccatat tagaagaagt ggctacttgg gtagttccct
    11401 ccttctctgt cgcatgaacc acacttccca taacaagact ggcaacagct acactagcta
    11461 ctccaatact aaatttacga attgaataat gtacttttct ttcgcttttt gatgcaaaca
    11521 taattatttc cttctatatt ttttctttaa ccttactata tcacttcaat atgaactgta
    11581 tat
//
LOCUS       DAVLZS010000055        10855 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLZS010000055 DAVLZS010000000
VERSION     DAVLZS010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.055"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            18..203
                     /gene="briC"
                     /locus_tag="VYO88_001713"
     CDS             18..203
                     /gene="briC"
                     /locus_tag="VYO88_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1719767.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            221..694
                     /locus_tag="VYO88_001714"
     CDS             221..694
                     /locus_tag="VYO88_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719768.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            707..943
                     /locus_tag="VYO88_001715"
     CDS             707..943
                     /locus_tag="VYO88_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1719769.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(993..1415)
                     /gene="nusB"
                     /locus_tag="VYO88_001716"
     CDS             complement(993..1415)
                     /gene="nusB"
                     /locus_tag="VYO88_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1719770.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(1408..1797)
                     /locus_tag="VYO88_001717"
     CDS             complement(1408..1797)
                     /locus_tag="VYO88_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1719771.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(1819..2379)
                     /gene="efp"
                     /locus_tag="VYO88_001718"
     CDS             complement(1819..2379)
                     /gene="efp"
                     /locus_tag="VYO88_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1719772.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(2508..3950)
                     /gene="gatB"
                     /locus_tag="VYO88_001719"
     CDS             complement(2508..3950)
                     /gene="gatB"
                     /locus_tag="VYO88_001719"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1719773.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LDGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(3950..5416)
                     /gene="gatA"
                     /locus_tag="VYO88_001720"
     CDS             complement(3950..5416)
                     /gene="gatA"
                     /locus_tag="VYO88_001720"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1719774.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAISSEDAKDSTSAPVRIADFTSKIGQGIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQRPVIFGGDN"
     gene            complement(5416..5718)
                     /gene="gatC"
                     /locus_tag="VYO88_001721"
     CDS             complement(5416..5718)
                     /gene="gatC"
                     /locus_tag="VYO88_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1719775.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            5931..7475
                     /locus_tag="VYO88_001722"
     CDS             5931..7475
                     /locus_tag="VYO88_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1719776.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            7744..8229
                     /locus_tag="VYO88_001723"
     CDS             7744..8229
                     /locus_tag="VYO88_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV1719777.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            8345..8533
                     /locus_tag="VYO88_001724"
     CDS             8345..8533
                     /locus_tag="VYO88_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1719778.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            8690..9055
                     /locus_tag="VYO88_001725"
     CDS             8690..9055
                     /locus_tag="VYO88_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1719779.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            9058..10725
                     /locus_tag="VYO88_001726"
     CDS             9058..10725
                     /locus_tag="VYO88_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1719780.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALRD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGTILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
BASE COUNT         3143 a         2049 c         2451 g         3212 t
ORIGIN      
        1 ttaagaaggt acttgcaatg acaggtacag aaacatttac agttatttca actgaggact
       61 tggagcaaac ttcaggtggt cttgctgttt gggaagatgg atatagtaga tggttatatt
      121 atagagaatt tgctccctat atgaggcaag gggcacttaa ttcttatata gatgcttgga
      181 agtacggctt ccgagcaggg taatctttca aaaaagtacg atgagaaaca caaaaaaact
      241 aagacaattt ggaatatttt tgcttattat tttactatct acctatttac cacaaacaat
      301 tggattgtat gtgacgatca ttttagggtt aggagctgat gtctattctc ttattttaac
      361 aatgggatta gtgggaagtt tccttctatt aatttggagg ttaaaaaaga aaaagatgct
      421 ctttatcttt gagaaaaaga gctggaactg gtcatttgtc ttctacttat ttgcaactta
      481 tgtggtttat cagattctcg gtaatttttg ggcacgctat gctcatttga ttaatcatag
      541 gaatattcat gatgagtatt ttaccgtgct tttttcaaat ggacaaccaa cctttttatc
      601 gactatctta tcttttgtcc tgcctgtaat catcggtcct gtttttgagg agactcttga
      661 tagagggtat tttatgaata ccttctttcc ctagtccaag tactatttgg atgttatcct
      721 atctgctatc atctttggga ttagccattt gatactatct cacagagatc caattagttt
      781 attatattat agtctgattg gtttcttttt tgcccttgtt tatcgttcta ccgacaatct
      841 gagattaacg attctctgcc atagtttttt taactttctc aatcatgcaa aacctatctg
      901 gatttttgtt tacaattata tctattatca tttttttaga tagtgggagg caaagaaaaa
      961 agtgtttgat atctatcaaa cactttttct ttttattgtt cttctgttac aaactggctg
     1021 agcagtccat tgataaaacg ggcagatttt tgatcggaga agtcctttgc aagctcgata
     1081 gcttcattaa cagcaaccag ctgaggagtg tcaaatgaag tgatttcaaa gactcccaag
     1141 cgaaggaggt ttctctccac gagcgttaag cgttcaatgg tccaacctgc ttttaaatgc
     1201 tgagtgattt gcttatctag ttcttccttt ttagcttgaa caccagaaac gaggtctatc
     1261 aaaaaggctg gaagttgtac atccgtatct tcacgatcat gagtataggc gaaacgacaa
     1321 gcagtttcga catccgtacc gaactcaagg ctcatgagag cttgaaaagc gcatttacgg
     1381 agttggcgtc tagattctaa tagtggacta gtcattgagg aagtcctcgt caaatagatc
     1441 tttcaattct ggttttggtg ttttatctgg gacgatacct gcaacgtgaa tattgatagc
     1501 agcgagttct acatcagcca tattacggac ggcatctttg acagctttct ggatagcaac
     1561 cgctacctta ggaactttta ctccgtactc aaggtagaga tagatatctg ctgtgagttc
     1621 ttcgtccacg tttttaagat aaatgccacg gccgagtgaa agttttgaaa gggtatcaga
     1681 cactgatctg tttgaaaaag agtgaacacc ctctaccttt gcagtagcga tagcaatgat
     1741 tttttcaagt acacgtgggg cgataacgat ttcgccaagt tgttcttcaa ttcccataga
     1801 atgacctctt tctagagatt aggcacgaga aacgtaagtt ccttctgcag tgttgataac
     1861 gagtttttgt cctgcttcga tgaagtctgg aacgtttacg acaagtccag tttccatcgt
     1921 tgctggttta ccagaacctg taacagtagc acctttgata gatggttgag tttcagcaac
     1981 tgtcaactca acagtagtag gaacggtgac accgatcact tcagttccgt agaattggat
     2041 tttcacatca gagttttcaa ggatgtaaag caattcgttt tcaacattga ctacagggat
     2101 ttcgtattgg tcgtaagttt ctgtattcat gaagtatgct gtgtcatcca ttttgtacaa
     2161 gtattgagct gggacagtct cgataatagc ttgttcaaat ttttcctctg gacggtagct
     2221 tgtgtcaaat gtagaaccag tacggacatc acgcaatttc atacgcatga tcgtgtttcc
     2281 tttacctggt ttgtggtgac tagcttccaa aacgcgaatc aatttgccgt cagctgtttc
     2341 aaaggtcata ccagctttta atttacttgc ttcaatcatg tttttacctc tttaataaat
     2401 attattactc ttcattttac cataaaatac tctggaaata aagccaaaat agttattggg
     2461 agttggtaga gaagaaaaaa ccaaccttag ggctggtttt gttctgtcta gttttctttc
     2521 aacttcgcca attcctgtgc aagtagttta agggcaactt gtgggttggc ttggcctttg
     2581 gttgccttca taaggaatcc tgtaaaggcc ttgtcggcgt tacgtttgcc tgacttgaag
     2641 tcggcaacag cagcttcgtt atcggcaaag acttggtgga tgattgggat caagatagct
     2701 ggatctgaaa tttgaaccat acctgctttt tccacgtatt cacgcgcgcc accgccattt
     2761 ttagctagat ggacaaagac tttcttggca atcttagatg aaatagtacc gtcttcgatg
     2821 atggcaatca tttcaaccaa gttttctggt gtcaattcga tttgttccag tgttttacct
     2881 tcagcattca agaactgagc gacttcccct tggagccagt tagagacttg tttggcatca
     2941 ccatctagag caacagcttt ttcaaagaaa tcagaagtga ctttattagc agtcaactga
     3001 ctagcatcgt agtctgataa accaaggtca gatacataac gcgcacgacg ttcttttgga
     3061 aactctggca actcagtccg catttcctca atccactcgt cagaaatttc aaagaggggt
     3121 aggtctggtt ctgggaagta gcggtagtct gcagcccctt ccttgacacg catgagaatg
     3181 gttgctttat tcgcttcatc gtaacggcgt gtttcttggc ggatttgacc acctgagcga
     3241 agaatttcag cctggcgttg gacttcgtat tcaagacctt tacgaacgtt tgagaaggag
     3301 ttgaggttct tcaattcagt cttggtaccg aatttttctt gaccataagg gcgaagggag
     3361 atgttggcat ccacacgcat agaaccttct tccatcttaa cgtcagaaat gccagcgtac
     3421 tggataactt ccttgagggc tgtcagataa gcataggcct cctctggcga acgcatatct
     3481 gcctcagata caatctcaat caagggaacc ccttggcggt tgaggtcaac ataagagtag
     3541 ccatctgtac catgggtgtt tttaccagcg tcttcctcta ggtgggcacg ttcgataccg
     3601 attttcttgg tcgtaccgtc ttctagtttg acttcaatcc agccattata tccgattggt
     3661 tcatcaaatt gagaaatttg gtaggctttg gggttatcag gatagaagta gttcttgcgg
     3721 tcaaagtgca tctttttgtg gatgtccatg ttgagggcaa gagcagcctt gataccggca
     3781 tcaacaaccc ctttattgag aactggtaga actcctggga aagaccagtc aatcacgtta
     3841 gtgttggcat tttggtcatt tccgaagtgg gcagaagtag gtgagaagat ttttgaattg
     3901 gtgttgagct ctacgtggac ttcaagtccg atgactgttt caaagttcat tagttgtcac
     3961 ctccaaaaat cacgggtcgt tgtttgtggt agtctgttgt tgcttcaaaa gcagcagcag
     4021 cttggtaaat ggtttcctca gagtacttgg gaccaatcaa ttggagtccg acaggtagac
     4081 cttgagagaa tccagcagga atcgaaattc caggcagtcc tgccaagttt acaggtatgg
     4141 tcaataggtc ggctaagtac atggcaactg ggtcatggtt gagagaatcc aagtcatagg
     4201 caacacttgg agcagttgga cccaaaatca aatcgtaatc cgcgaagact ttttcgaaat
     4261 cttgaatgat aagtgtacgg acctgtccag ccttcttata gtaggcatcg tagtaacctg
     4321 atgaaagact gaaagtaccc agcatgatac ggcgcttcac ttcttcacca aaaccttggc
     4381 ttcggctgtt tacatagatt tcatcaaggt tggttgcatc ttctgcgcga tagccgtaac
     4441 ggataccgtc aaagcgttgc aagtttgatg aagcttctga tgaagcgatg atgtagtata
     4501 cggcaactcc gtatttagag tgaggaaggc tgacttcttc gacaatagca cccaattttt
     4561 caaagtgttt agcggcattt agaatggttt ccttaacctc tgggttaatt ccttcaccga
     4621 ggtattcctt aggcaaagcg attttcatac ccttgatgcc ttggccgatt tttgaagtaa
     4681 agtcggcgat gcggacagga gcagaagtag agtctttagc atcttcgctg gaaatagcgt
     4741 tgagcaagag ggcattttcc ttaacagtag gagcaaaagg tccaatctgg tctaatgagc
     4801 taccaaaggc aatgagaccg aaacgtgaaa ctgttccgta ggttggtttg agaccaacga
     4861 ttccgttgaa ggcagcaggt tggcggatgg aaccaccagt atcagaacca agtgacaagc
     4921 gaacttgtcc tgaggctaca gctgcggcag aaccacttga tgacccacca ggaaccttgc
     4981 tgtggtccca agcgttttta gttgctccgt agtgtgaagt ttcacctgaa ccacccatag
     5041 caaattcgtc catgttggtc tttccaacga caatcatgcc cttggttttt gcattggcaa
     5101 cagctgtcgc atcaaagatt ggctcatagt tgtagagcat ttttgaggca gcagttgtaa
     5161 gaataccgtc tgtagagatg ttatccttaa cagcaagtgg aattcctgaa aggacattgt
     5221 cagcatcaat tccagcttca tcaatggctt tagcttgaac aagagcttgc tcctcagcga
     5281 tggtgacaaa tgaattgagg gcttcctcac gagacttgat attttcaagt gttgcttggg
     5341 tcaattctgt tgcagaaatt tccttagaga caaggagatt gtgcaactct tcaatagttt
     5401 tattgttaaa agtcattagg catctcctcc atcgtctagg atagctggca ccttgatata
     5461 gtagttgtct ttttcaggta cgtttttaaa caagcgatca cggtctgttc cttcttcggc
     5521 cacatcaggg cggagtacag tcttgcggtc agccatagtc gtagtaggtg cgacaccagt
     5581 tgtgtcaact tcgcccagca attcaaccat gtcaacaatc ttagacaagg tggtcgcaaa
     5641 ggcagcagtt tctttttcag agaatcttaa ttttgaaaga ttggcaacgt gtgttacctc
     5701 ttcttgcgta attttcatct tgcatccttt cgtgaaatga tgatttttag tctgttctat
     5761 tttaccatat tttcctataa ataagggagg gggaagtgaa aagaaataga aattgaaaaa
     5821 aatgctaaaa tccgatataa tggagtgttg aaaggaatgg taaaatccaa tgtaaaaatc
     5881 attctcagct attgaaacaa gaaaaataga gaatcaaaga aagagaactt atgaatattc
     5941 aagaagaaat taagaaacgt cgtacctttg ccattatctc ccacccggac gcggggaaaa
     6001 caaccatcac tgagcagtta ctctactttg ggggtgaaat tcgtgaggct ggtacggtaa
     6061 aagggaagaa aacagggact tttgctaaat ctgattggat ggatatcgag aagcaacgtg
     6121 ggatttctgt tacttcatct gttatgcaat ttgactacga cggcaagcgc gtgaatatct
     6181 tagacacgcc agggcacgag gacttctcag aagataccta tcgtaccttg atggcggtgg
     6241 atgctgcggt catggtcgtg gactctgcca aggggatcga ggctcaaacc aagaaattgt
     6301 ttgaggttgt gaaacatcgt ggcattccag tctttacctt tatgaacaag ctggaccgtg
     6361 acggtcgtga gcctttggat ctcttacaag aattggaaga aatcttgggc attgctagct
     6421 accctatgaa ctggcctatc gggatgggga aagcctttga gggcttgtat gacctctata
     6481 accaacgttt agagctttat aaaggggatg agcgttttgc tagtctagaa gatggggaca
     6541 aactttttgg tagcaatcct ttctacgagc aagtcaagga tgatattgag cttttaaatg
     6601 aagccggaaa tgagttttca gaggaagcta ttctggctgg agaattgacg cctgtctttt
     6661 tcggttcagc cctgacaaac tttggtgtgc agaccttcct tgaaaccttc ctcaagtttg
     6721 ctccagaacc acatggtcac aagaaaacag acggtgaaat tgtggatcct tatgacaagg
     6781 atttctcagg ctttgtcttt aaaatccaag ccaacatgga tcctcgtcac cgtgaccgta
     6841 ttgcctttgt tcgtatcgta tcaggcgaat ttgagcgtgg catgagtgtc aatcttcctc
     6901 gtactggtaa gggggccaaa ctatctaatg ttacccagtt tatggcggag agtcgtgaga
     6961 atgtgaccaa tgccgtggca ggtgatatta tcggggttta cgataccggt acttatcagg
     7021 ttggggatac cttgacggtt ggaaaaaaca agtttgaatt tgaacccctg ccaaccttta
     7081 ctcctgaaat tttcatgaaa gtttctgcta agaatgttat gaagcaaaaa tccttccaca
     7141 aggggattga gcaattggtg caagaaggag ccgttcagct ttataagaat taccaaacag
     7201 gtgagtacat gctaggcgct gtaggtcaac tccagtttga agtctttaaa caccgcatgg
     7261 aaggcgagta caatgcggaa gtagttatga ccccaatggg taaaaagacc gttcgttgga
     7321 ttaagcctga ggacttggat gaacggatgt cgtcaagtcg caatatctta gccaaagacc
     7381 gttttgacca accagtcttt ctctttgaaa atgactttgc cctccgctgg tttgcggaca
     7441 agtatccaga cgtagagtta gaggagaaga tgtgactcag taccaacaat tggaactaaa
     7501 gttccaaatt gttggacgct agtcgctatt tggcgaacta gctaactgcc tcactaacta
     7561 cgtttggcaa atgaaatcga tttgtaaaac tccgtgtcat aatgtaaaaa ttgtaaaccg
     7621 taatgggact tcatctaaaa tctccactgg tatggtttta cgaacgaata ggcgaaaata
     7681 atggttacgt agaaacatat gatgggaata atatgatggg aataaaaaga aataagataa
     7741 agagtgaaag aagagaaaaa agcgattgtc ttaggtgcag ataatgctta tatggataaa
     7801 gttgaaacaa caataaaatc tctttgtgtt catcattata atcttaagtt ttatgttttt
     7861 aatgatgacc ttccgcgaga atggttccaa ttgatggaaa aaagactaga gactttgaat
     7921 agtgagattg tgaatgttca gattgacagt agtattctga aaggttatcg tctccccttt
     7981 gagggacttt catatgcggc tttttttagg tattttattc caaagtatgt aagcgagtct
     8041 cgtgtactgt atttggattc agatattgtt gtaagaaaat cgatagatga gctgtgggat
     8101 ttggacttga cggctatacc cttagctgca gttagagatg atttttatac acataatttt
     8161 aattctggtg ttctgttaat caacaatggc atgtggagag cagaaaatgt cacgcaagac
     8221 ctgatttaag acacaaataa aaaatcttcc aattcccttg caaaaaacaa gaaagtgtga
     8281 taacatagta cggtatgtgg tgctagcaca tccgctatat tagatctaat aggaggaaaa
     8341 cacaatggct aaagtatgtt actttacagg tcgtaagact gtatcaggaa acaaccgttc
     8401 acacgcgatg aaccaaacaa aacgtgccgt aaaaccaaac cttcaaaaag ttactgttct
     8461 tatcgatggt aaacctaaaa aagtttgggc ttcagctcgt gctttgaaat caggtaaagt
     8521 tgaacgcgtt taataataaa agcaaaggag accttagggt cttttttctt ttattgtggg
     8581 tataacatcg tttgaaaaat agagtaaata tccgctgata catcattctg cttttacact
     8641 tgggctgaaa tatgataaaa tagagtatca actagttgag gtaaaaagga tgactgtaaa
     8701 aattaataca aaagatggtc aaatcgaact aacagatgaa gtgattgcaa ccgtcgtagg
     8761 tggagcagca actgagattt ttggtgtggt cggtatggct agtaaaaatg ccctcaaaga
     8821 taatttccaa gccctgctag gtaaggaaaa ttattctaaa ggtgtcgtcg taaaggcagc
     8881 cgaagatggc agtattgcag ttgatgtata taccgtgtta agctacggaa caaagattag
     8941 tgaagtgtca aaaaacattc aagagcgtgt tgcctttagc ttggaaaacc agcttggaat
     9001 tactgctcag actgtaaatg tctacattca aaatatcaaa gttgtaggag aataaccgtg
     9061 tcaaaaatta ctactagctt atttcaagaa atggtgcagg ctgcatcaac tcgcttgaat
     9121 aagcaagctg aatatgtcaa ttcattaaac gtctttccag ttccagatgg agatactggg
     9181 acaaatatgg gaatgaccat tgaaaatggt gctaaagaag ttgcagacaa gccagcttct
     9241 acagttggag aagtagcgag cattcttgcc aaagggcttt tgatgggtgc gcgtgggaac
     9301 tcaggagtga ttacatctca gcttttccgt ggattttccc aagctatcaa ggataaagac
     9361 gagttaacag gtcaagactt ggctctggcc ttccaatcag gtgtggaagt tgcctataag
     9421 gcagtgatga aacctgttga aggaacgatt ttgacagttt ctcgtggagc tgctatcggt
     9481 gctaagaaaa aagctgagca aacagatgat actgttgaag tcatgcgcgc agccttggaa
     9541 ggtgctaaaa cagctctagc taaaacacca gacatgcttc cagtattgaa agaagttggc
     9601 gttgtggact caggtggtca aggattggtc ttcatctacg aaggtttcct ttcagccctt
     9661 actggcgaat atattgcatc tgaggacttt gtagcgactc ctgccaacat gagtgagatg
     9721 atcaatgtag agcatcataa gtctgtagct ggtcacgtag cgactgagga catcacgttt
     9781 ggttactgta ctgaaatcat ggtagctctt aagcaaggtc caacctatgc taaagatttt
     9841 gactacgatg aattccgtaa ctacttggat gagcttgggg attctctcct cgttgttaac
     9901 gatgatgaaa ttgtcaaagt ccatgttcat acagaagatc caggacttgt tatgcaagaa
     9961 ggtctcaaat atggtagctt ggtcaaggta aaagttgaca atatgcgtaa ccaacacgaa
    10021 gcacaggttg agaaagaagc tactcaagtt atcaagtcgg ctgaagaaaa agagtatgct
    10081 ttgattgctg tggtggctgg taaaggtcta gcagatatct tctgttctca aggcgtggat
    10141 tatgttatcg aaggcggtca aaccatgaac ccttcaacag aagactttat caaggctgtt
    10201 gaacaggtca atgcccgtaa catcatcttc ttgccaaaca acaagaacat cttcatggca
    10261 gctcaatctg cggcagaagt tttggagcaa ccagcagtag tggtagaggc tcgcactctt
    10321 cctcaaggta tgacaagtct tcttgccttt gatccaagca agtccattga agaaaatcaa
    10381 gagcgtatga cagctgctct tagagatgtc gttagcggaa gcgtcacaac agccgtgcgt
    10441 gatacaacga tcgatggctt agaaatccat gaaaacgata atctaggtat ggtggatgga
    10501 acaattcttg tgtcaaaccc tgatatgcac caaacattga ctgaaacctt gaaacatatg
    10561 ttggatgaag acagtgaaat cgtaaccttc tatgtcggtg aagacggaag cgaagaactt
    10621 gccaatgaaa tcgctcaaga aatcgtagaa gaattcgaag acgttgaagt cgagattcac
    10681 caaggtcaac aacctgttta cccataccta tttagtgtgg aataagatta atgaaggact
    10741 gagaaatcag ttcttttttc ttttttagta aatgaaatcg gtatcttttt aataaaaaca
    10801 aaaataacat tcataaataa acgttaaaat agaaaattca gaaaatttct tcttt
//
LOCUS       DAVLZS010000056        10757 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLZS010000056 DAVLZS010000000
VERSION     DAVLZS010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.056"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(120..1544)
                     /locus_tag="VYO88_001727"
     CDS             complement(120..1544)
                     /locus_tag="VYO88_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1719781.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKRIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2087..4366)
                     /gene="pulA"
                     /locus_tag="VYO88_001728"
     CDS             complement(2087..4366)
                     /gene="pulA"
                     /locus_tag="VYO88_001728"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1719782.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLTPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKIETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTSAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4478..6436)
                     /gene="ligA"
                     /locus_tag="VYO88_001729"
     CDS             complement(4478..6436)
                     /gene="ligA"
                     /locus_tag="VYO88_001729"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1719783.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLENLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6529..7707)
                     /locus_tag="VYO88_001730"
     CDS             complement(6529..7707)
                     /locus_tag="VYO88_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1719784.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLVLTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7787..8650)
                     /locus_tag="VYO88_001731"
     CDS             complement(7787..8650)
                     /locus_tag="VYO88_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1719785.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     AKSSTTPLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFDN
                     LYSFYDVDYITRIGREVMEREEFYQEIGRHKRLVLILALNCYQHCLDHLSFDNASYFE
                     AYTEKIIGKGIKLYERNAFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8653..10554)
                     /locus_tag="VYO88_001732"
     CDS             complement(8653..10554)
                     /locus_tag="VYO88_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1719786.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTASNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSALYLGDYDYYIEKKVEVEMSQIEEASTNNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLETEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3231 a         2376 c         1903 g         3247 t
ORIGIN      
        1 agctgtacta ttctagtttc aatatactat aataccaaaa agttcgtatt ttttctataa
       61 ttattattat tttatagcaa aaaaataaaa ccaggaaaac aatttcctga ttttacacgt
      121 tatttcacat caaaaacaat ggatttgaca tttgtcatcg cttcaatgct atatttaatt
      181 ccttgcactc cagctccaga acctttgaca ccaaggaatg ggaaattatc tggaccacgc
      241 tgggttttat tattaatgtg gactgtacct acttcaagtt tttcagcaat ttcaaaggct
      301 tttttgaaat catttgtaaa gactgatgat tgaaggccga attcagattc gttggcaaag
      361 gcaatagctt cctctacact agccacacga atgattggta aaacaggacc aaatggctct
      421 tcccatgcca ctttcatatc ttttgtaact tggtcaaaaa gcactggcca gaggagattg
      481 ccctcacgtt tgattggtgt aagagcctga gcctcttttt cttgtgcatc ctcaatcaag
      541 ccccaaatga agtcggctga agcattgtca ataacaggtg taatatcagc attgtcaaat
      601 ggatcaccaa ctgttaattt agaaacttct tcctgaagca aagtagctaa tttatctgct
      661 acactttcga gaacaatgac acgtttaata gccgtgcaac gttgtcctga gtagctaaag
      721 gctcctgcaa caatttgctt ggcagcatgt tccaaatctg catcttctag tacaagagct
      781 gcatctttcc caccaagttc caacatgata ggacgcatac cagctaaacg accaatacgt
      841 tctccaatag gagttgaacc tgtaaagttg atgaagttga cttctttgtg ctcaatgata
      901 taatccccaa tttctgaacc acgacctgta atggtgttga aaacacctgc cggaatccct
      961 gcttcttcaa atgctttagc caacaagagt ccagaaatgg aaccttgtgt tggtggctta
     1021 aacatgacca cattccctgc aatcaaggca ggtgcaattt tagaagcaga taaattaact
     1081 ggataattaa aaggagcaat cgctagcacg ataccaactg gttcacgacg gacaacagcc
     1141 agtttgtttt tacttgctgc ctcaaaacca ccaccttcca ttgcttgtcc agtgatacgg
     1201 agaccttcct cagcagcata acgaatcaag tctgctgtac gcactacttc tccaattgct
     1261 gctttaatcc tttttgctac ttctttggca aggatagtac caatttcttc cttatcgcgt
     1321 tctaaaatag ctgctgtttt atgcaaataa gccgcacgtt caactgctga taaagctcgc
     1381 catgctggca gggctgcacg cgcagcttgc atagcctcat cagcttcagt ctgagtcatg
     1441 gctggaactg tacccaattc ttcttgattg attggtgaat aaatcgtaat ttcttgttca
     1501 gatgatttcc attttccatt tactaaattc tgatatcttg tcaaattttt gtcctcctga
     1561 aaatgattaa gatatatttt agcaaatttt cagaaaatca caaccctttt tgcaaaattt
     1621 ttgagattat tttcacaagc ttgatttttc aaagtatact caataaaaat aaaaaaatcc
     1681 actacgtcaa ggcgagacta atgtggtttg aagaaatttt cgaagagcgt gaatgagtat
     1741 catctatagt aaaataaaaa actgaacaat ttggttgggg acagccaaac caatttctca
     1801 caatgtttta gaaacaaggg tgtgctattc caatttcagc ctactataac tgtcatagat
     1861 tgttgaaaca aagtctaggt aaaagtcttc ataataaaaa gacctcctat caaatgttca
     1921 aaaactttga taggaggtct tgtttcgtta aaatatttat caaattttct atacaagtga
     1981 gctgttagcc aggttctttc tattctttca atttcaatga atggattttt tatcaatact
     2041 cataactggg aatttgtctg tgtaaaaata gcgagataga tggtatttat aaaacactca
     2101 agacagctag actaatatca tttaaaacat tatcttcttt tgagcgactg ttggttacca
     2161 acatagctaa atttcctgca ttttcaaatt gatagggttc tgatttagca ttcacaacca
     2221 ccaagaggtg ttctttgccg tgaacttcat agataaggca gccgctatgt tcaatcgcag
     2281 aatgcacaaa gacatgatgg taaatttcat catagctaga gtaagaaaag gcactagttt
     2341 ttgtcttcaa tcggatgact tgacggataa actcaatact gtcttgacgc tcattaatca
     2401 agttccagtt cacttggttc acactgtcag gagcattata gctattcatc gcacgctctc
     2461 tatcatcatg ggtcaactca ccattttcac cagtcgcaac cagtttggta cgaccaaatt
     2521 cttgaccgat ttccataaag gccatcccct gcatgagcag attcatggct gtggcagttt
     2581 cgatcttgcg catgatttgc tctgaacttt ggtctggatg aagggttgcc aataaatcgt
     2641 gaagattgta attgtcatgg gcttctacat agttaagcac ctgatttgga tgtgtatagc
     2701 ttcctaattc acgacttcct aggattgctt tagctagaat tggctctgtc gcagcaccac
     2761 tgacaaaacc tgacttgata gcaccataaa cttctccccc tttgacagca tcgcgctgat
     2821 tgtcattgaa gaaaccaata tttggcatct ggtaggcatt gtccttcttg gccttatcat
     2881 aaggggtaag acctgttccc atatcccatc cttctccata gaggataatg ttggagtcga
     2941 tttcatccaa gctttgacga atcatctgca tggtcttgac atcatgaatc cccatcaagt
     3001 caaaacggaa gccgtcaata ttatattcct gcacccagta tagaagagaa tcaatcatat
     3061 acttgcgaaa catttcgtgt tcactggctg tttcatttcc aacacccgtt ccattctgga
     3121 aggtaccatc tggattcata cgataatagt aatcagggac tgttgtttgg aatggtgcat
     3181 caacaactga gaaggtatgg ttatagacta catccataat gactccaata cccgcatcgt
     3241 gataagcttg aaccatcacc ttcaaatcac gaatgacctg agctggatca tctggattag
     3301 ttgaaaaact agtttctggc gcgttatagt tttgtggatc ataaccccag ttgtaggtta
     3361 catttccatc ctcatcgtat tctttatgac ggtctgcaat tggttgcaat tgaacataat
     3421 tgtagcccag cttcttgatg taatcaaaag cagttgactg gccgtattgg ttaactgttc
     3481 cagcctgagc agcacccaag aaagttcctc gaagatgttc atctacaccc gatgtaggtg
     3541 atttagtcaa atcacgaata tgcatttcac agataactgc cttacatgga ttttccaagc
     3601 gccaagtagc ctccgaaccg tgcttaacct cgaagttttc aacttgcttt tctacatggc
     3661 tcagaatagc tgaacgtttg ccatcagggc tggtcgcgat tgtataagga tcacgtgtca
     3721 gtgtttggtg atgagggaat tggacttgat actgataagc cttacctacc aaatcttcct
     3781 caacatccaa actccagaca ccgattgtat tgtccttatg attataagag tagctattgc
     3841 ctcttttcat ctcaaaagtc ttccaaacgg gtgcatcatt agcagctgat tcataaacga
     3901 caacttgcac ttctgtcgct gtaggtgacc agagggaaaa atgagcctga ttgtcctcta
     3961 cacggcaacc caattctcct tggtaacccc aatgatgatc aaaactagca ctgttaatgg
     4021 ccttatcaaa ggcaaaagga ttttgatttt tatagaaagg actggcaata gcaggatttt
     4081 cagagtaata aatcctatca tcgccttcca aaatccagac ctctgttaat aggggatagt
     4141 gattaaaacg gatagaatat tctttactag tttgacctgt atgaaccaca aaattcaagc
     4201 tttctataac atgtgaactt gggtgttcaa agctaaataa agctccaaaa taatcttctt
     4261 tgtaggttag caaatcaatt cgttgatcct gactttttac aaaggagcaa gtgtcatatt
     4321 ctccattctt acgatggtaa tgaatgcgca tagggtagtt atacattttt tatttttcct
     4381 ttttactttg tttctatttc actaataaat ttttgtcaat ctcgtctcaa ttaacagaca
     4441 tagtcatatt ctctaaactc tgtttttaaa caatccatta caaactttct agccatgcct
     4501 catctctgac ctggatacca agttcttgtg ctttttgcag tttacttcca gcgtctgcac
     4561 ctaccacgac gaggtcggtc tttttagaaa cactacctgt cactttggca cccagatttt
     4621 cgagtttact tttagcttct gagcgcttga gtcgttccaa ttttcctgtc aataccacgg
     4681 tcaaacctga caaggccgca tccgctacta ccgtctgtcc tttatagtcc agattgaccc
     4741 cagtttcttt caattctctg agcagaattt cagagccttc tgtcgcaaaa taagtctgaa
     4801 gacttttggc aatcacgcca cctagacttt caatactagc cacttcctct gaatctgcct
     4861 gatacagatt ttcaattgaa tggaaatatt gaagtaaaag ctgactagcc ttgcttccga
     4921 catgacgaat tcccaaacca aataagagct tctcggcaga attttccttt gatgcttgga
     4981 tagcctgata cagtttagca gcggactttt ccttaacccc ctctaaaagg aggaaatcct
     5041 cttcttgcaa acgataaata tccgccacat ccttgactaa attagcagca aaaagcttct
     5101 caacaataga tggaccaagg cctgtaatat tcatagcatc acgagaagca aagtgaatca
     5161 agccttccat gatttgagca gggcaacgcg gattgataca acgtagggcc acttcatctt
     5221 caaagtgcaa caagtcagag ttacaacttg gacagtttgt agggatatct agtttttctt
     5281 cagaaacccg tttggactct accacacgta aaacggcagg gatgatgtca ccagccttat
     5341 atacaatgac cgtatcgtct tttcggatat ctttttcagc aatataatct acattgtgca
     5401 gggtcgcacg gctaacagtc gtaccggcaa gttgtactgg tgttagatta gcagttggag
     5461 ttacaacacc ggtacggcca actgtccagt caactgataa gagttgagct tctttttctt
     5521 cagcagggaa cttgtaggct actgcccact ttggagcctt aacggtaaaa ccaagttctt
     5581 cttgacttgc taggtcgttg accttgatta ccactccatc aatatcgtaa ggcagatttt
     5641 cccgttcctg tcctacttct tggataaaat tccagatttc atctatgttt tcagccaaga
     5701 ttcgcttagg attgaccaca aaacctagtt gttctaggta cttcaaaccc ttttcttggc
     5761 tatcacgagt tgaagggctg gcttcttgat agagaaacgt tgcaagatta cgcttggcaa
     5821 ctactgctgt atccaactga cgcagagttc ctgctgccgc attacgagga ttagcaaatt
     5881 caggctctcc attttcttgg cgcacttggt taacttggtc aaaggaagcg cgtggcatgt
     5941 aacattcccc acgaactgtg atatctagtt cttctggcaa agtcaaaggg atgtccttaa
     6001 cacgcttgag gttttctgtg atattttcac caattgaacc atctccacgt gttaccccag
     6061 caaccaaaat ccccttttca taagtcagcg agatagataa gccatcgatt ttcagctcac
     6121 aaatataggt cggatgagcc acttccttac gaacacgcgc atcaaaagca tctagctcct
     6181 cacgtgaaaa agcatcctgc aaactataaa gaggatactg atgactgtat ttttcaaaac
     6241 catctaaaac cttgccacca acacgatgag tcggactgtc tgctagcact tgctctggat
     6301 aagcagtttc taactcgacc aactcacggt aaaggcggtc atactcactg tctgaaaccg
     6361 agggattatc gctggtatag tactcagtcg catagcgatt gagcaaagcg actaactcat
     6421 tcattctttt attcataaga ccattttacc ataaaacaag ccctcctcac aaacgagaag
     6481 ggcggaaaaa acacttagtt tgaaattatt tttgaaactc aagcaacctt atatcaattt
     6541 ttcaaaatga gttcgaacat aaataaacga tatacaagac aagatgataa caccacttcc
     6601 aattatcagg aaagaagaga gatgtacact tggcaagact gtcataaatc cttttgcaat
     6661 aggcataaat agaatagcta aggtaaaaat tgtactcagt actctcccaa gaaattcgct
     6721 ctcaaccttg gtttgtactt gagtaaaaaa gtgaatatta aaaatcgtca taaacaattc
     6781 acaaactaaa tttccagaaa aggaaagaaa agttggaagt ggtaatccca tcataaaaac
     6841 tccgacacct gtcaaaacca gtaaaatcaa aagattataa atattagctt taattttact
     6901 agctagaaga gccccaatga tggaaccaat agcccccata gttaaaatac ttgcataggc
     6961 tccttctgac ccgtaaagct gattcgaaaa gggaagtaga aattcaaaag ctgcaaaaaa
     7021 gaaattaacg ctggaagcta ccagcaaaag gaagaaaatt tcttgctgat gccagatata
     7081 gtgtaaccca tccttgatat ctacaaaaat atctctccca gtaaaagcct ttttctcttg
     7141 aacttttgct tcctcttttg gaaggaaagc cactagaaca aaagcaatga aaaaagtcag
     7201 cgagtctagc agtagcgtca tatggagact tgcaaactgt aaaacaagga aggaaagaac
     7261 aggagagcta acacctacaa cctgcaaaac cagctctaag cgagaattat agatcacaat
     7321 ctcatctttc tccaccactt cagttatgat agctttattg gctgtgcgag aaaaggcaaa
     7381 agcaatagcc tgcacaatgt tagcaacaat caaagcgcca atcatccagc tatcattcct
     7441 tatgaaagaa atagccagac aaagaatccc acaaacaaga tctgccgtca ttaaaatctt
     7501 acgacgagaa aaacggtctg aaataactcc gccaaaggga ttgacgagaa tagatgtgac
     7561 gagctcagaa atctgataca ttcctaaaac tgtctgtcct atagtcccca tagaagccaa
     7621 ccagacacta tttccataat catagagcat atttcccatt ttattgatag ccccacggct
     7681 aatcaactgc actgcatagc gattcatatt aaagctcctc tcaaattttg aaactattgt
     7741 atcaaaaccg aaaggagctt tttatttttt cccttatttg ggaaaattaa cttttgacaa
     7801 atttttcgta gtgttcctga taataggcta cttgctctgg aagacctaac acatcaaaaa
     7861 tatgcatggc ctcttgcatc tgcttacagc cttctttaca ctgtcctttt tgatataagg
     7921 caaaaccttt taaataatgg aaagcattac gctcataaag cttgatccct tttccaataa
     7981 tcttctctgt ataagcctca aaatagcttg cattgtcaaa agaaagatga tctaaacaat
     8041 gctggtaaca attgagggcc aaaatcaaca ctaatctctt atggcgacca atctcttggt
     8101 aaaattcctc cctctccata acttctctac caatccgagt gatataatcc acatcgtaga
     8161 aactatagag gttatcgaaa agaatcaact catacatggt ccattcttct gttttgaaga
     8221 gataatctgc taccttatcc aaatcatcct gcttcatatc ataagtcgca tctctttgac
     8281 aaatcagacc ctgtagcaaa atccagttca gctcaaaata aaggggagtc gtcgaactct
     8341 tagccttttc aagttgttct ctttgaagct tttgaaaacc tgcaatatcg tttgaatagt
     8401 aaagtgggat aatctgtgcc atcatagaca catgttcatg attatgaaaa ttccttgcct
     8461 tatccatgaa attttcgatt gtgacatgaa tgttatccaa tatctcaaaa aaacgggaga
     8521 ctgctaggtc agactcccca agctcaaagc gagataactg agaggttgaa caggattccc
     8581 ctgctgcctc ctttaaggaa taatttccac ttgttcgaaa ttcacgaaat acttttccaa
     8641 gatgttccat ctttacacct gctctgataa ttcttcccat tcaagcatag cttcttcctg
     8701 acgatggctg attttgtcca gctcagcctg caattccatg agtttatcgg catcgtttgt
     8761 ttccaacatt tgttcagaaa tggcttgact ttgactttct aactcttcga tttcagtttc
     8821 tagactttca atttgtcgca tgagtttgcg aacttctttt tgactttctt tctgggcctg
     8881 ataatcgttg actggacttg cttcctttgc ttgattgtta gttgaagctt cctcaatctg
     8941 actcatttct acttctactt tcttctcaat atagtaatcg tagtctccaa ggtagagagc
     9001 cgagccattc tcagacaatt ccaaaacatg agttgccaca cgattgataa agtaacggtc
     9061 gtgactgaca aaaagcaagg taccgtcaaa gtcaatcaaa gcattttcca acacttcctt
     9121 gctatcaata tccaagtggt tggtcggctc gtccagaatc aagaagttgt tgttttccat
     9181 agataattta gccaaaagca aacgtgcttt ctcgccacca gacagcatgc cgactgattt
     9241 tttaacatca tcaccagaga aaaggaaggc acctagacga ttacggattt caacttccgg
     9301 tgtcagttta aaatcattcc aaagttcatc taggacggta ttactcgctg tcagcttgct
     9361 ttgagtctga tcatagtagc caacctcaac attagcgcca aagcgcttct cacccttgat
     9421 aaaaggaatc tggtctacta tagacttgat aaaggttgat tttccgatac cattgggacc
     9481 aacgatagca acagcattca tcttacgaag gtctaggtta atcggttgtg acaggacttc
     9541 cccatcatag ccaacagccg cattttcaac agtcaaaaca acattgcccg acgttttttc
     9601 agactggaag gtcatgttgg ctgctttctt gccagcttcc ggcttgtcca aacgctccat
     9661 tttttctagt tgtttacggc gagattgagc acgtttggtc gttgaagcac gaactagatt
     9721 gcgattgaca aagtcttcca gagcagcgat ttccttctgt tgcttttcat agttttttgc
     9781 ctcagtagct agcttttgct ccttcaactc gacaaaacga gagtaattcc ccacatagcg
     9841 atccaaggaa tgcttggtca aatctagcgt aattgtcgca accttgtcca agaaataacg
     9901 gtcgtggctg acgataatga gggcaccgct atagtttacc aagtaattct ctagccagga
     9961 gatggtttca atatccaagt ggttagttgg ctcgtccaag accaagagat tgggcttttc
    10021 aaggagcatt ttagctagag ccaaacgagt attttgacca cctgaaagtt cagctatttt
    10081 catctgccac atagactcgt caaacttgaa tccattcaaa atcgctcgaa tatcagcttc
    10141 ataggtaaag ccgcctgctt ggcgaaaatt ctcagataag tggtcgtaat ctgacatcag
    10201 tttatccaaa tcctcaccag acttttcacc catctccaac tccatctgac gaagttgttt
    10261 atctgtccga cgtaagtcat caaagacatg aagcatctca tcatagatgg tattttcaga
    10321 ctcaaaacgg ctatcttgag ctaggtaaga cagagaaata tcttttttct tattgatttc
    10381 tccactagtt ggctcctctt ctccaactaa aatcttcaaa agagtagact tacctgcacc
    10441 atttttccca acaagggcaa tccgatctcg ttcatcaacc tgcaggttga tattatcgaa
    10501 aagaacctct cctgcaaaag aacgttcaat tttattagct tgtaaaataa tcatacaagt
    10561 agtatagcat gtttccctaa gtcattcaag ataatcgtaa gtcttttagt acaactttta
    10621 taacataaaa taaactaaat tatgtatatt ttatattaga ttccttcact atcttgttgg
    10681 attttctaac cagctaatct tgtttcaaat agttatcgca caagtctatt atttaattct
    10741 tttcattatt tacgtac
//
LOCUS       DAVLZS010000057        10541 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLZS010000057 DAVLZS010000000
VERSION     DAVLZS010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10541
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.057"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(45..1994)
                     /gene="mutL"
                     /locus_tag="VYO88_001733"
     CDS             complement(45..1994)
                     /gene="mutL"
                     /locus_tag="VYO88_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1719787.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLASA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            2350..2790
                     /locus_tag="VYO88_001734"
     CDS             2350..2790
                     /locus_tag="VYO88_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719788.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLIEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            2787..3245
                     /locus_tag="VYO88_001735"
     CDS             2787..3245
                     /locus_tag="VYO88_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1719789.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            3555..4817
                     /locus_tag="VYO88_001736"
     CDS             3555..4817
                     /locus_tag="VYO88_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1719790.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(5110..5580)
                     /gene="nrdI"
                     /locus_tag="VYO88_001737"
     CDS             complement(5110..5580)
                     /gene="nrdI"
                     /locus_tag="VYO88_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1719791.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(5658..6191)
                     /locus_tag="VYO88_001738"
     CDS             complement(5658..6191)
                     /locus_tag="VYO88_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1719792.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            complement(6243..7529)
                     /locus_tag="VYO88_001739"
     CDS             complement(6243..7529)
                     /locus_tag="VYO88_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719793.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGHPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICCAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            complement(7541..9187)
                     /locus_tag="VYO88_001740"
     CDS             complement(7541..9187)
                     /locus_tag="VYO88_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1719794.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            complement(9189..9803)
                     /locus_tag="VYO88_001741"
     CDS             complement(9189..9803)
                     /locus_tag="VYO88_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1719795.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            9938..10507
                     /locus_tag="VYO88_001742"
     CDS             9938..10507
                     /locus_tag="VYO88_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1719796.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
BASE COUNT         3105 a         2411 c         1947 g         3078 t
ORIGIN      
        1 cgtttttctg attttgaaca tttttcccag acttttttat acttttaata tttccccaac
       61 tcacggagac tggtgtgatt ttcctgaata cgtcggaaca tcttttccat atctgacttg
      121 gtaaaatgca ccaaaacagg acgtccgtga ggacagttat agggattgtc acattgagaa
      181 agctgataga ggagttgtct agctgaatga tcatcaatac gatgattggc cttgatagat
      241 cgcttgcaag acatcatgat agccagctct gctcggtatt tcttgataga aacttccttg
      301 gtcaaaagga gcatgtcgca catctcatag atgcctgatt caatctcttc ttctgccatc
      361 caaataggat gttcacgtag aataaattga ttttctccgt actctgctag aaagacgccc
      421 acttcctcta agagaggcat tctttccttg agacgcaggg catcatccgc aggaaattca
      481 aagatatagg gcactaggag ttgctgctgg ctctggtcaa cattgccaat gctttcacgg
      541 tactcctcgt acttgacccg ttcctgagca gcgtgctgat ctatgatgta aagtccatct
      601 cgcccttggg caaagagata agtcccgtgc atttgtccga aaaactccaa ctctgggaag
      661 ctggatgctt cttctcgctc cagtttgtca taagccttat cgatgctagc aagatctaac
      721 tctggatggt ctagctggtc gtagttagca ggctttctct ctgcaaaatg cagttttgct
      781 ggcttggtca atcggtccaa ggtttccttg gcaaacaggg tcaaatcctg cccttcatca
      841 gtcaattcta cctgataatc agctacttca gtttgactag gtcttgacgg ctcagttttc
      901 tcatagtaga gcgtattttc tttgagtggg agaatagttt gctccacctt ctcacgattg
      961 cgcacggtcg atttggcaag attttccaag gcatctggaa tcaaggtttg ttccttgaga
     1021 ctatttgcaa tagcttctga aaccagagtc atcagttctt tttccttgga aatccgcacc
     1081 tcttgcttag ttggatgcac attgacatcc gctagataag ggtcgatatg gatgtgaatg
     1141 acagccagtg gaaaacgtcc aaccataagc ttgcttccaa aaccatccaa aatagcacga
     1201 ttgagcagga agttcttgat ataacggcca ttgatgaaga ggctgatata attgcggtta
     1261 gcccgagtca actcaggcaa ggacacaaaa cctgaaattt cgaaatctag gtcagagttc
     1321 tcaatttcaa tcatcttctt ggcactcgcc aaaccgtaaa tccctgcgat tgcttggcgc
     1381 aattgaccag tccctgctgt tcgcgtcatt tccttgccat cactaatcaa gctaaaagaa
     1441 atctcaggat gggccaagcc cagacggttg acaatatcaa tgatatgaga caactccgct
     1501 tgctggctct tcatatactt gagacgggca ggcgtgttga aaaagagatc ctccacacaa
     1561 accttggttc ccacaggact agtcgctggg atgacttcct caacttcacc cccacgcgcg
     1621 actaacttgg ttccatgact agcaccatcc accgccgtta acagagtcaa gacactaaca
     1681 gacgcaatag aaggcaaggc ttcaccacga aaaccaagcg tccgaatccg aaagagatct
     1741 gcttgatttt ttatcttact ggtcgcatgg cgacgcaggg ccaactccac ctcatcgtgg
     1801 gcaattccat aaccgttatc tgtgatttgg attttcttga gaccagcttc ctcaatctca
     1861 atgataatct gactagagcc cgcgtcaatg gcattttcta ccaactcttt aaccacactt
     1921 gcaggacgtt caatgacctc tccagccgca atctggtttg ccagcatctc tggcaattca
     1981 ataatatgag acatctttca gcccctttct gtatctattt tcctagaaat tgattagtgc
     2041 tattatacca tatttcagaa agaacagaaa agctccacca cataggagcc caatccctcc
     2101 acatagacaa agtaccttgc cagagggagt aaaatagtgg tatactcaat aaaaatcaaa
     2161 gagcaaacta gaaagctagg cgcagacagc tcaaaacact gttttgaggt tgtagataaa
     2221 actgacaaag tcaacaacta tcctacggca agacgacgct gacgtggttt gaagagattt
     2281 ttgaagagta ttaataaagg tgtacaagaa gtgagattaa ttttgtatga aaaacaagga
     2341 gagaaattta tgaaagtaga attacagatt agtgagactt acgaggagga aaagctgatt
     2401 gtccaagcac ctcagccgac agataaagtt cagaaagtca tcgagttcgc agaaaatctg
     2461 gaccaaagag aaaaaatcaa agggaaaatc gatgatcagg tctatctagt tgagattggc
     2521 aagattcagc gcttctatat cgagaatcgg aaggttctag cagaaaccgc gagtcagacc
     2581 tacagcattg atttgcgact ctatcaggtt cttaaactct tgccaaccaa ttttatccaa
     2641 atttcccaat cagaaatcat caatatcgat tccatctctc acctcaagct cacgccaaac
     2701 ggtctgatag aaattttctt gaaaaacgaa agcttcacct actcttcacg ccgttatcta
     2761 aaaaccatca aggagaaatt agaactatga aaaaacaagt atttcacgat gcagctaccg
     2821 gtgttcttat cggcctcatc ctctctatcc tcttttcact catttatgca ccaaatacct
     2881 acgcaccact aaatccctac tctctcatcg gccaagtgat ggatcagcat caggttcacg
     2941 gtgccctggt cttgctctac tgcacactta tctgggcaac catcggtatg ctcttcaact
     3001 ttggcaaccg cttatttagc cgtgactgga gcatgcttcg tgccactctg actcatttct
     3061 tccttatgct ggctggcttt gtcccactag caactcttgc tggttggttc cctttccact
     3121 ggattttcta cctccagctc attatcgagt ttgcgattgt ctatctcatc atctgggcta
     3181 ttctctataa aagagaggct aaaaaagtag atcacatcaa tcaactcttg gagcatagaa
     3241 aataggaacc tcataataag caaatccgag aaagaaactt ctcggttttt ctttatcctg
     3301 ctgcacctta ctatagtgaa atgaaataag aacaggataa atcgatcagg acagtcaaat
     3361 cgatttctaa caatgtttta gaagcaaagg tgtactattc tagtttcaat ctgctatatc
     3421 ataacagtta tttcagattt tctttgtaaa ttttctatct tttttcaaaa tattcttgca
     3481 tttttccaaa attttttgta gaatatagat tacatataca gattattctg aaaattcaaa
     3541 aaggagtatt tatcatgtcg caagctattt ccttaaatca atcaacctgg gcaagcaagc
     3601 taaaagcaat gggacctgga atcctaatgg caactgccgc tgttggaggt tcccacattg
     3661 tatcctcaac tcaagctggc ggttcttacg gttggtctct acttctcttg gtcatcttag
     3721 ccaatgtctt taaatatcca tttttccgtt ttggtgctga atacacagct gatactggaa
     3781 agactttggt tgaaggttat gccgaaaaag gaaaactcta tctctggatt ttctttatcc
     3841 tcaatgtctt ttcggctatg gtcaacacgg ctggtgttgc cattctgtgc tcagctatca
     3901 tcgccagtgc cttcccaatg attggactta gcattactca gtggtccctc attctcgttg
     3961 caatcatttg ggctatgcta ctctttggag gctacaaact tttagacggc atggtcaaat
     4021 ggattatgtc tgccttaacc attgcgactg ttcttgcagt tatcattgcg gcggtcaagc
     4081 atccagaata cagttctgat tttgtcgaga agacaccttg gcaaatggca gctctgccct
     4141 tcatcgtctc cctcctagga tggatgccgg ctcctattga aatttcagcc atcaattcac
     4201 tttggtcagc tgaaaagaga aagaccgtca actttaacac agaagacgct ctgtttgact
     4261 ttaacactgg ttatattgga acagctatcc tagccgtctt ctttgtggca ctgggagcac
     4321 tgattcagta tcctacaggg caggcggttg aagctgcttc agccaaatac atctctcaat
     4381 tcgtgggcat gtatgcctct gttcttggcg aatggtcccg ttacttgatt acctttattg
     4441 ccttcctctg tatctttgga acagttataa ctgttatcga tggctattct cgcgttaatc
     4501 aggaatctct ccgactgcta atcagtcaaa aagaggacaa tcgtaaatct ttgaacatct
     4561 ggatgaccat cactgctatc atcggtatcg tcattatcaa gttcttcgct ggtcaggttt
     4621 caaccatgct ccgctttgcc atgattggct ctttcctgac aacacctttc tttgctcttt
     4681 tgaattacgc cttggtaacg cgtgaaaaca aaaatcttcc ttcttggctc aaacaccttg
     4741 ccattgcggg attgattttc ctctttggct tcgccatctt ctttatctac gcactcgcaa
     4801 tcggaaaagc agggtaaggg acaagcgcga gatgaagata aggtttcatt tcaagagaaa
     4861 attcagcaaa tatttctatg ataaaaagca taagaacaag gttttgaaga cctgaactta
     4921 tgctttttta cgttcttaaa gactgtttat actcaaaaaa cagttgaaca acttcaacca
     4981 cctcttataa gaactttata ctattcgaga atctcttcaa accacgtcag ctctatctgc
     5041 aacctcaaag ctgtgctttg agcaacctgc gactagcttc ctagtttgct ctttgatttt
     5101 cattgagtat taattctcct tttccaactc atacaaatct gcgataatag ctgcgacatg
     5161 tttgatatct tccagcatgc ctcgcatttc aaagtcagcc aatacaggga agccaaagcg
     5221 ttgactgtat tgcttggctg ttaggcagta ttggttatta aagttacgat ttcctgaccc
     5281 aaccacacca aaacacttac tagcattgtt accataggca ataaaatctc ccaccggtgt
     5341 cgtcaaaatc tcaacatctc cgttatccac gccattccca ccttcgagat aggtcggcaa
     5401 aaaagcgaca tagggatggt ccatttcata gaaatttttg ccttccttga ccaaatcctt
     5461 gatatgaatc ttttgaacct caatcccttt gtactgggac aagagatagt ctttcaagcg
     5521 cgtcacaaaa ctttcagtgt tgccactcaa actaatataa actaaagaaa ttgtcttcat
     5581 atgtacctcc atgattttat ctataatcaa aaaacaacta ccaagattgt atcttgatag
     5641 ttcttttttg tcaatactta ggtaagctct tctgtttcct cttcttctgc caaggctttc
     5701 tgttgtcgcc acatcttata gaagacaagg gctaggaaga gaacattgat gacgatatag
     5761 aaaatgctaa cagcttttga accaatactc actgtcaaac gcatgctctc atcttgaacc
     5821 aactgcacag cgtcttgtaa accaacatag ccataaatcg aaccaataat agctaacaaa
     5881 acatagccaa cgtaagtata gtttgcatat tgcaaatttt tacgaacaag gaagacaatc
     5941 gctacgacca ctaaaatagt agatagcaca atcaaagcaa cattaaaaat agaatgagat
     6001 gcttctgcta ctctataggt ataattaagc tggtcttcta attgctgagc attgacccct
     6061 gcaacttgtt tctgagcagc acgaagggct tctttactag gcaagggact cacaattcca
     6121 aacagagacg gaactgaaat aagggcagac aagattagca aaacccatag ataaattggt
     6181 ttctttttca tgataggacc tcctgataat attatagcac cttttgtaaa ggaatacaaa
     6241 tcttatagta tagtttctac ctgttttcgg taggcttttg gcgattttcc gcacaatttt
     6301 cggaaaactt tatagaaata tccaaggtta ctgtaaccaa cagcacaaca aatatcttcg
     6361 atgctgtcac tagttgaaag caagagctgc tgggcagcct taatacgttg tttatttagt
     6421 aactctgcaa aggtcgaatc ggtttcacgc ttaatcaact gccctagata gacaggattg
     6481 ataaagaggg ccttactgat atccttgagg gaaagctctt tttggtaatc acgaccaatg
     6541 acttccagca cactgaccac attttcattc atacggtatt gaccgaaaaa gctgatcaga
     6601 gtttccttga tataagaaac caattcatcg aaggattgaa tagcatgaat ggttttgaca
     6661 atgtccgtca tatcatcagc tttgagatgt tcaaataaat ggaaaacatc catgacaaac
     6721 tggataaaaa gctgtttagt aatcgaaaca cgaggtgtat tttcaagaac taccttctcc
     6781 aagagattta actcttctac gatttgattg agatttccct gaatgataac cctataaatc
     6841 ggttcgtaat aggcaaagag actctcagac tgctgcagat ttacagaacc gtaaaagagg
     6901 gttttctcag cattcagctt ccagcgttca aaatgttctt gataaggagc ttcaaaaggt
     6961 gtaacgacta aaccatctag ggggtggcca gaaatgaaaa tctgccagtc ttgacccaag
     7021 acatagtagg gaatggtgaa ggaaccttgt ttttccttgg atagacctat ccaccaattc
     7081 tccttatccc ctaaataact aacaaatcca gcctcgtcta attcttgact aagagtctga
     7141 cttttcttcc ctctctcgcc gagctgacct gcaatcttct ccagcagatt tcccagctct
     7201 accttatcaa caggcttgac caaatagtcc accacactaa ggttcattgc tctttttaca
     7261 taatcaaact cctgataacc tgagagcagg atataggcag catctggtaa gatctctttc
     7321 atctcccgaa tcatatcaag tcctgttttg tctggcatat tgacatcgga aatgatgaca
     7381 tcgacaggat tttcctgaac atattctaga gcttcatcgg catgactggc tgttgcgacg
     7441 acctccatat cccacttatc aaagggaatc aaacgcttca gaccttctgt caccatgtac
     7501 tcatcatcta ctaataatac tttatacatt ttctcccttt ctactcatct tgaattgtaa
     7561 tacgatactg aacaccggct tgctctgcag actctatagt aatggcatag cggtctccaa
     7621 aatagagcac aaaacgctcg tgtacattga caatcccgat agactgcctt tgatcactgt
     7681 agctggcttg gtgttcaaaa tatctctgac ttaatttttc tcggatattt gccaactttt
     7741 cagccgacat tcctctacca ttatcgacca ccaaaatttc cacaaaacca tcctgtttaa
     7801 gagccttgat gctaatcaca ttatctgtcc gcctgtggtc aacaccatgc gcgaaatagt
     7861 tttctaccag cggttgcaag gtaaacttgg gaatcttcat attctctaac tctggatcta
     7921 tcttgaaacc ataggcaatg gacttgggat agcgaaccat gcagagatag ctgtatttac
     7981 ggcaaaattc taattcctgt ttgaggaggg tctctctttc gtcggaaata ttgttacgca
     8041 agagactact gaattcataa atgatatctg ccaactcatc ttgactctgc ataactgcat
     8101 acatgcgcaa gaactccagc gtattataca taaaatgagg attgatttgc gcctgcaagg
     8161 ctcgcatatt ggcatctttt tgactaagct ctaactggta aatatcatgg atattctttt
     8221 ccaatcgatc caacatatca ttggtcgtct ccgcgattag gagtaattcc tgatctttct
     8281 cggaaatgtc aatccgacgc ccctcttcgc cttgagcaat gacttgaatg gattctacta
     8341 aatccactac ctgcttttgg taattagcaa aagtctgcct caaagtcaga taaagaatga
     8401 caataaagag aaggctcaaa cccacaatca aagcagagct agtcactgtt ccttgtaaaa
     8461 caaagttttt aggaactgcc acctgaacct gatatccatg agaagttaag ccaactagcc
     8521 aattttcact ctccttatca actgtctcac caatatgaaa aatctccgta tcaaaaggtg
     8581 aggtcactgt tactgccatc ggagtatgac ctctagtatt atcaatggca tggtataaaa
     8641 cagcaggatc caaggagatg taaatcactc ctaaatcttg atctgacact ggatctgaca
     8701 ccggaatggc aaaactattt cctgctggtt tgaaatcctc agccctgatt ttttctccac
     8761 tacgtttgtc tttagtagaa acatagactt ccttgtaatc ttgaaaagca atggccaccc
     8821 cagttacaaa atcatttcga acatagaggt catcaacatt ttcatacaga gagactgata
     8881 tataaggcga agctttccgc tctaattgcc agtaaaaata gtctggcatg ctaaggctaa
     8941 agtatttata gattccctcg atacgagctt gattttcaac taaagcctga gctatctggg
     9001 ttgactctct atggtaatat tcaatttcac tcactgttct agcagttaca cgctgggcta
     9061 ctctctgggc ttccttttca cgtgaatccc agtcagcgta agagagtaag attgcaaaac
     9121 tcgcaatgat aatgatcatc actgaactat aggttcttag aagcgtatgt agccaaaact
     9181 gcttcattct attttgtcgc caatttttca tggatgattt catagacagg ttccaacata
     9241 tcactgataa agaaatgcca catcccaatt cctacaaaaa atagcagggc aggcatataa
     9301 taaccaattg ctacaagtag cacagtccca aggagaacct tagccacagc tgctagactc
     9361 ataaagatgc caatcaagga taatttgaga ctatttcgat aggacaaggc aaaataaact
     9421 tgtaatttta aagatactgt ataagccaaa aagatcaggg caactactag gacattcaaa
     9481 agggtcgcaa tcaaatgaac aatggtctga tgaggcaatt gcaccaagag atacaaacca
     9541 taggtcaaaa ctagacccac acctaaaaag ctatagaaaa tcaggttgct tgagacaaaa
     9601 ttttgcttgt aaagagacca agcctccttc aaactgtatt cccgaaagct ataaccatgt
     9661 tctgcatata agctcatcaa ggtggcacta gccggcgcta gaccaaggat aatccctcct
     9721 gctaaagtta atagccaaaa gaaggctgtc gcaatcatcc ctaaaaagaa acgattaaag
     9781 acaaagtcta aaaatctacc catgatattc ccctaaaaat aactatgaaa ccattatatc
     9841 atatttcaag cgttttcaaa aacttctagt atccatttac aatcccacca aaccatgata
     9901 aaatgagaat tgtgaaaaaa ttatcaggag acaattcatg aagaaatcta tcttaactac
     9961 actgcttttt gcagttcttt acttcctctg catgggaatt ggtgtccttt tgggcaatct
    10021 ctttgaccaa actggaaaca tgttttatgc gcctgccttt actgcccttg tcggcggtag
    10081 cgtctatatg atcctagtcg caaaagttcc gcgctttgga gccattacca ctatcggcct
    10141 tgtcattgcc ctctttttct tgggaactaa acacggtgct ggttccttcc ttcctggaat
    10201 tatctgtggc ctcctagcag atggagtagc tcatttagga aaatacaagg acaaaacaaa
    10261 gaacttcctt tctttcatta ttttcgcctt tagtacaaca ggaccaatct tgcttatgtg
    10321 gattgcgccc aaagcctata tggctactct tctggcaaga ggaaaatccc aagaatatat
    10381 cgaccgtatc atggtcgctc caaaccctgg aactgtcctt ctatttatcg caagtattgt
    10441 catcggagcc ctagtgggtg ccttgattgg acaagccttg agtaaaaaat ttgcccagaa
    10501 aatctgatca gttaaaaaga gccacgcggc tcttttttat t
//
LOCUS       DAVLZS010000058        10429 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLZS010000058 DAVLZS010000000
VERSION     DAVLZS010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10429
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.058"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..402
                     /locus_tag="VYO88_001743"
     CDS             <1..402
                     /locus_tag="VYO88_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1719797.1"
                     /translation="RSLKGQLIRGKVSGRRYQRISLVAGLTNGELIAPMTYEETMTSD
                     FFEAWFQKFLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKFLPLPPYSPEHNPIE
                     KTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            368..748
                     /locus_tag="VYO88_001744"
     CDS             368..748
                     /locus_tag="VYO88_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1719798.1"
                     /translation="MRLFCLVLVSIDYINCLSETTDKNWHKSDRVFVTNTGKTVHSSI
                     LSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSI
                     YTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(886..2190)
                     /gene="eno"
                     /locus_tag="VYO88_001745"
     CDS             complement(886..2190)
                     /gene="eno"
                     /locus_tag="VYO88_001745"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1719799.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2354..2800
                     /locus_tag="VYO88_001746"
     CDS             2354..2800
                     /locus_tag="VYO88_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV1719800.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKIWEVKKEEPAKTSLWKKWFS"
     gene            complement(2797..3912)
                     /locus_tag="VYO88_001747"
     CDS             complement(2797..3912)
                     /locus_tag="VYO88_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1719801.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4026..4250)
                     /locus_tag="VYO88_001748"
     CDS             complement(4026..4250)
                     /locus_tag="VYO88_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1719802.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            complement(4195..4566)
                     /locus_tag="VYO88_001749"
     CDS             complement(4195..4566)
                     /locus_tag="VYO88_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV1719803.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4625..6058)
                     /gene="glgA"
                     /locus_tag="VYO88_001750"
     CDS             complement(4625..6058)
                     /gene="glgA"
                     /locus_tag="VYO88_001750"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1719804.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQTYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6055..7194)
                     /gene="glgD"
                     /locus_tag="VYO88_001751"
     CDS             complement(6055..7194)
                     /gene="glgD"
                     /locus_tag="VYO88_001751"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1719805.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7184..8335)
                     /locus_tag="VYO88_001752"
     CDS             complement(7184..8335)
                     /locus_tag="VYO88_001752"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1719806.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPL
                     KEASRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGM
                     SDFGKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWK
                     IYSRNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMS
                     GAIIGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8325..10253)
                     /gene="glgB"
                     /locus_tag="VYO88_001753"
     CDS             complement(8325..10253)
                     /gene="glgB"
                     /locus_tag="VYO88_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1719807.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3162 a         2293 c         1850 g         3124 t
ORIGIN      
        1 cgctcattaa aaggtcagtt aataagaggc aaagtatctg gaagaagata tcagaggatt
       61 tctttggttg caggtctaac aaatggtgaa ttaatcgctc caatgactta cgaagagacg
      121 atgacgagcg acttttttga agcttggttt cagaagtttc tcttaccaac attaaccaca
      181 ccatcggtta ttattatgga taatgcaaga ttccatagaa tggggaagct agaactcttg
      241 tgtgaagagt ttgggcataa atttttacct cttcctccct actcacctga gcacaatcct
      301 attgagaaaa catgggctca tatcaaaaag cacctcaaaa aggtattacc aagttgcaat
      361 accttttatg aggctctttt gtcttgttct tgtttcaatt gactatataa attgtctaag
      421 cgaaacaacc gataagaatt ggcacaaaag cgaccgtgtt tttgttacca atacaggaaa
      481 aacagttcat agttctatct tgagcaagtc tctccagcga gcaaacgaac gccttaaaaa
      541 accaattccc aaacatctgt cccctcacat cttcagacac accactatta gcatcttatc
      601 agaaaataaa attcctttaa aaacaatcac ggacagggtt ggtcattccg actctgaagt
      661 cactacttcc atctacaccc acgtcacaaa gaacatgaaa gatgaagcaa tcaatgtact
      721 ggataaagtt atgaaaaaga ttttttaaaa agttttgccc cttttttgtc ctctaaatac
      781 aaaaatagcc cttcggataa aatccgaggg gctagaaacg ttgttaaatc aacggccgaa
      841 cttttgaatt tcatggttcg ggataaaata gttcactgaa ctattttatt ttttaaggtt
      901 gtagaatgat ttcaatccac gatattcagc tacttcacca agttggtctt cgatacgaag
      961 caattggttg tatttagcga tgcggtctgt acgtgaaagt gaaccagtct tgatttgtcc
     1021 tgcgttagtt gcaactgcga tatcagcgat tgttgaatct tcagtttcac ctgaacggtg
     1081 tgatacaaca gcagtgtaac cagcttcttt agccatttcg atagcttcaa aagtttcagt
     1141 aagagtaccg atttggttaa ctttgataag gattgagtta gcagcacctt cttggatacc
     1201 acgtgcaagg tagtcagtgt ttgttacgaa gaagtcgtca ccaacaagtt gtactttctt
     1261 accaagacgt tcagtaagag ctttccaacc atcccagtcg ttttcatcca taccatcttc
     1321 aatagtgatg attgggtatt tgttaaccaa ttcttcaagg tagtcgattt gttctgcaga
     1381 tgtacgaaca gcagcacctt caccttcaaa tttagtgtag tcgtaaactt tacgttcttt
     1441 atcgtagaat tctgatgaag cacagtcaaa tccgataaat acgtctttac ctggtacata
     1501 tccagcagct tcaatcgcag caaggatagt ttcaacacca tcttcagttc cttcgaaacg
     1561 aggagcaaat ccaccttcgt cacctacggc agtttccaaa ccacgtgatt taaggatttt
     1621 cttaagagcg tggaagattt cagcaccgta acgaagggct tctttaaatg ttggcgcacc
     1681 aactggcaag atcatgaact cttggaaagc gattggagcg tcagagtgag aaccaccgtt
     1741 gatgatgttc atcattggag ttggaagaac tttagtgttg aatccaccaa gatagctgta
     1801 aagtgggatt tcaaggtagt cagcagcagc acgagctaca gcgatagaca caccgaggat
     1861 tgcattcgca cccaatttac ctttgttagg agtaccgtca agtgcgatca tagcacggtc
     1921 aatagcttgt tgatcacgta catcgtagcc aatgatagct tcagcaatga tgttgtttac
     1981 gttgtcaaca gctttttgtg taccaagacc accgtaacga gatttgtcac cgtcgcgaag
     2041 ttcaactgct tcgtgttcac cagtagaagc tcctgatgga accataccac gtccgaaagc
     2101 acctgattca gtgtaaactt ctacttcaag tgttgggtta ccgcgtgagt ctaggacttc
     2161 gcgagcgtaa acatcagtaa taattgacat tttttactct ccttatgagt taaatttttt
     2221 acacctctat aataccttaa aacccctcct ttttcaagaa aaaacgttat ctttgtgcaa
     2281 cttttcctta actttataaa gtaatcgctt tcttttgtct gttttattct aacttttatg
     2341 atatactgtt ttcatgacag atttatcaaa acaattactt gaaaaagctc atggtgggtt
     2401 aaaaataaat ccggatgagc aaagacgcta tcttggtact tttgaggaaa gagttcttgg
     2461 atatgtagat attgacacag caaatagccc tcagttagaa aaaggctttt tatttatttt
     2521 agaaaacctt caggaaaaag cagagccact atttgtgaag atttcaccaa ctatcgaatt
     2581 tgataagcaa gttttctact taaaagaagc aaaagaaact gatagtcaag ccaccatagt
     2641 atctgaagag catattactt ctcctttcgg cctggttatt catagcaatg caccagttca
     2701 agtagaagaa aaagaccttc gacttgcttt tccaaaaatt tgggaagtta aaaaggaaga
     2761 accagccaaa acatccttat ggaagaaatg gtttagctaa atcttgcaca tatttaataa
     2821 gtgcccaata ttggcagccg tgcgctccag atagagactg gcatttttca aactatcttc
     2881 taaaggttca cttttctcca aaatagaaaa gacagcttgg atattttcaa atggtagggg
     2941 aggtaaatct tcagcaagac taccgcaaat agcaataaca ggaactccaa caggggttct
     3001 ttttgcaaca cctataggcg ctttcccagc aaagctttga ctatcaagtc ttccttctcc
     3061 aacaacaacc aagtcagcat ctgaaacttt cttatcaaag ttgattaagt ccaagcaggt
     3121 atcaattcca gacacgatac ttgcctgagc aaaggcacac aaaccaccag caaggcctcc
     3181 acctgctcct gctcctttaa tttctaatgt tgcaggtgag aatttttcat aaaaatcttg
     3241 gatcgcctga tctacgactg caaacatagt cggatgtaga cctttttgat tgccaaaagt
     3301 gtaagtcgca ccttgatgac cacataaggg actcacgaca tctgctagaa tatgaatttg
     3361 aacaccttca ggaattttat agcaattttc tgttgaaaca gaagctaagt ttaataagga
     3421 ttgaccggaa gcaggcaaga catttccatc cctatcataa aattgataac ctaaaccagc
     3481 agcaatcccc agtcctccat cattactggc cgtgccacca acaccgatat aaatatcttt
     3541 aatcccttta gaaatgagat ggagaatcaa ctctccaata ccacaagttt ggatttgaag
     3601 tggatttcgt ttctctagcg gaatttttcc aagaccaacc aagtcagcta cttcaaatag
     3661 tgccagttcc cctttttgaa aatagcgcat ggcttctttt tgtccaaaag ggtctgtcac
     3721 ttggatccat ttttctttta ggtcaagaga atgtcggata gcatctacag taccttctcc
     3781 cccatcacca acagggcaga ggagacattc tacatctgct atcgattgtt ggaagcctct
     3841 ttttattgct tcagctacct gttgagctgt caagctttcc ttaaacgaat ccggtgcaat
     3901 tacaatcttc atattttccc tcattctaaa cagtcaatca aaggaagaac ttctaaaaaa
     3961 tccctcttgt caacatgatg tggtatttct tttttgagca tttctttgga acaaaaggcg
     4021 attcctcact ccgccgactt caacattaat agattattga ccccatcacc gattgccacc
     4081 gttctttctt tagaaagttt tagtttcttt ctccattttt ccagagtttc ttttttgacc
     4141 tggggactta taatttgtcc aactaatttt cctgttaaaa gaccttcttt gacttcaagc
     4201 tggttggcag tgaaataggc aataccaagg gattttgcta atctctccaa ctattggtgt
     4261 aaatccacca gacaccagac caactaggat gccattcttt tggagaatag agatgaactc
     4321 tgggacattt agcgatagat gaattgagtt gaagacgtta tcaaagacca aaataggaag
     4381 accttccaac aaggacactc tttttcttaa actgctttca aagaccaact ctcctcgcat
     4441 tgctcgactt gtaatctgcg aaatttctgc ctcatgacct gcctctctcc ctaaaagatc
     4501 aatcacttct tctaggatta aggttccatc tacatccaaa acacacaagc cttttacttg
     4561 agacatcagt tctcctctct aaacagccta aaaatcgtat gaagtcatca tacgatttta
     4621 tctattaatt aactaaacta tggtacaagt caaggtatga cttgcaggct gtatcccatg
     4681 agaagtcact ctccatagct tgtttttgta ggtttctcca aatgtctgga tggtttctat
     4741 acaagtccaa tgctgtttgg aaagtccaat ttaaccaata aggagataga ttgtcaaagc
     4801 taaagccagt accgcttcct tcgattggat tgaaagcgcg aactgtatct cgcaagcctc
     4861 caacttcatg gaccaatggc aaggttccat aacgcatagc catcatttga gacaagccac
     4921 acggttcaaa acgacttggc atgaggaaga ggtcacaagc agcgtagatt tcctgagcaa
     4981 gtttgacatc aaaagtgata tttgttgata gcttgtctgg gtaaatctga gcaaaccatg
     5041 agaaagctcc ttcaaaggct ggatcgccag ttcccaaaag aacaatctga acatcttctt
     5101 gcaagatatg gtgaagactt tcgaccacca catcaaaacc tttttgacgt gtcaaacgag
     5161 aaacaattcc caccagtgga acgtctgctc taacaggcaa gccaactctt tcttgcaatt
     5221 ttgccttatt tttggctttc ccagacaaat cttcctgatt gaaatgatag tctaaaagag
     5281 catccgtctg aggattataa agatcagcat caatcccatt cacgatacca gatactttac
     5341 cagactccat tttaagaatc tgatccaaat tacatccaaa ctgactagtc ataatttcat
     5401 gagcatagct aggtgaaaca gttgaaacac ggttcgcata gagaatacct gccttcatcc
     5461 agttcagaca gttgttccat cgaagggtgc catcagcgta acgttcaaag ccaactccaa
     5521 acaaatcacc caacattcct tctgaaaatt gtccttggaa ttctaaatta tgaatggtta
     5581 aaactgtttc aatgtcctca taggtttgaa tccaacggta tttttccttc aacaagaaag
     5641 gaatcatagc tgtatggtag tcatgaacat ggagaagatc aggaataaag tcaatccttt
     5701 ccatagcctc aatggcagcc agttggaaaa aggcaaagcg ttctccgtca tcaaaatcac
     5761 cgtaaacatg accacggaag aaataatatt gattgtcaat aaagtagaag gttacaccat
     5821 ttaatactgt tttcttaatt ccacaatact gtctgcgcca accaacgctc acctcaaaat
     5881 gaagcacatc ttcaatctga cttccaaatt tagcctctac catatcatag tagggtaaaa
     5941 tcactgcaac ttcgtgccca gcttttacca gtgattttgg aagagcgcca atgacgtctc
     6001 ccaaaccacc tgtttttgaa aagggtgcac cctctgctgc tacaaataaa attttcatga
     6061 atgaatatcc tctgttactt tagcaccttt cttaaccaca actggatgtt ctgcagttcc
     6121 tcgaatcaca acaccaggct caacttcaac ccctttgtcc aagatagcat attcgacctg
     6181 agccccttct ccaataacaa cacgagggaa gagcaggcta tctttaacca agctatcctt
     6241 atggacatga atattacgtg atagaacaga attagctact tgaccttcaa taatactacc
     6301 agaggcaaac tgagaagtgc ttaccttaga tgtattagca tagtaagttg gctcttcgtt
     6361 tttgaccttt gtataaatct tttggtttgg tgagaaaaga gaatagaatt tttgtgattc
     6421 aagcatatcg atattcgctt gataataaga tttaacagag tgaatattgg ctagatagcc
     6481 cgtgtactcg taggcgaaag ctccctcttt tacagccaaa tcccgtaaaa catagcgcaa
     6541 tttctctgga tgttcttttt tagcttcttc ttccaagtgt tcaatcaacc aaggtgtatc
     6601 aacgacaaag atatctgtag acatattgaa cgtttcagct gttgacttgc tatcaaagag
     6661 tttatgagaa agaacatggt ctgtttcatc tacatccaag attgcattta cttctgaaat
     6721 atctttctta gctagttttt tataaactac agtgataggc tcttttgttg tactatgtag
     6781 gtggaaaact tggttcaaat caatgttaat aagaacatcg cagttgaggg caaccgtttg
     6841 gtttgagcca gaacgtttca aataagtaag aagctgttgg tagtattctt ttccaactgt
     6901 actactttct acacgggtat tgtaaattcc tagatagtaa tggctaagaa gggttgataa
     6961 gccccactcg cgtcctgaac gaatatggtc aaatactgag ctgatattat cctgctggaa
     7021 aataccaaag acactacgaa cacctgcatt agcaaggctt gaaagtggga agtcaatcaa
     7081 acgatatttc ccaccaaatg gcaaacttgc tactggacgg tggtccgtca atgtcgacat
     7141 attgtgaaaa ccaactgtat ttcctaaaat ggcagaatat ttatcaatct tcatctgttg
     7201 ctacccccac tacttcatta tatcctacaa cttgtacttc atctgttcca tcaatttcga
     7261 caccgtcaga aataatcgca ccttcaccaa taatggcacg tttaatctta gctccttgac
     7321 caatgatagc tccactcatg ataactgaat caaggacttc cgctccttcg cgaacttgcg
     7381 cgcctgttga aaggatagaa tgtttaacag ttccatcaac gaaacatccg tctacaacta
     7441 atgagtcttc cacatgagca tttgccccga ggaagtttgg tggtgaaatc aagtttcttg
     7501 agtaaatctt ccattgacgg ttacgactat ccaaggcatt ttctggagaa atatactcca
     7561 tgttcgcttc ccaaagtgac tcaatagtac caacatcttt ccaataacca ctaaattcgt
     7621 aagcataaac actttcacct gactcaaggt aatttggaat gacattttta ccaaagtctg
     7681 acatgccaac cttgctcttt tcagcagcga ctaacatatt acgaaggcgt tgccaatcaa
     7741 aaatgtagat tcccatagaa gcttttgtag atttaggttg agctggtttt tcttcaaatt
     7801 caacaatacg attgttagca tctgtgttca tgataccaaa acggcttgct tctttaagag
     7861 ggacgtctaa aactgctact gtcaagctgg cattattatc cttatgagac tggagcatat
     7921 catcatagtc cattttgtag atgtgatccc cagacaaaat caagacatac tcaggattga
     7981 cactgtcgat atagtcgata tagtcgatat tttggtaaat agcgtgacta gtcccctcaa
     8041 accaacgatt tccttcactt gcagaataag gttgaagaat agagacacct gaattaatac
     8101 cgtctagtcc ccagcttgaa ccattcccaa tatggttgtt gagagcaagt ggttgatact
     8161 gtgtaacgac cccaacattg tgaatccctg agttggcaca gtttgatagg gcaaagtcaa
     8221 tgatacggta gcgcccacca aattgcacag ctggttttgc gatgctttga gtgagtttac
     8281 cgagacgagt tccttgccca ccagcaagaa tcaaagctaa catttcattt ttcattttct
     8341 actccttttt ggtttttatt tgtgacggtt ttagtagatt tcaagcgacg tttgattttc
     8401 catacacttg ctcccatagc cggtagggta aaggttaagg tctgctcata atctttccat
     8461 agtccttctt gcgtttgaac agtttgatta tgttctttcc aaacgcctcc ccactcttcc
     8521 aactcagtat tccatacttc ttcgtaaatt cctgcaacgg gtagtccgat tgtaaaatct
     8581 ttccgctcaa caggtaccat attaaagata cagactaaca tttctccctt tttaccctta
     8641 cgaataaagg aaagaacact ctggtctcga ttatccgcat caatgatttc aataccatca
     8701 tagctggtat caatttccca cagacagcga tgatctttgt aaaactggtt tagctgagaa
     8761 gtgaaatact tcatcttagc attcattggg tcttctaggt tagaccattc caactgttct
     8821 tcagatttcc attctaggaa ttgaccgtat tcgctaccca tgaagagcaa tttcttacca
     8881 gggtgacaaa tttggtacgt atagagattg cgcaagcctg cgaattgatt gtaacgatct
     8941 ccccacatct tatgcatcat actcttcttg ccatgaacca cttcatcgtg cgagaatggc
     9001 aagagataat tctccttgaa aacatacata aagctgaaag tcaccaggtt aaagtcatat
     9061 ttacgataaa tcggatcttc ttcgtagaaa cggaggatat cattcatcca gcccatgttc
     9121 catttgtagt caaatcctag accaccaatc tctttcattc ccgtaatctt ggttgcagac
     9181 gaactttctt ctgcaatcat catcacatct ggatattcta acttaataac ttcattcaag
     9241 cgttgaagga aataataacc ttcatagttg agatttccgc catctttatt aggtgtccat
     9301 ggagcatcat catagtccaa atagagcatg ttgctaacag catccacacg aataccatcc
     9361 aaatgataga catcaatcca atgcttaatg caagaaatta agaaggactg gacttcattt
     9421 tttccaaggt caaaattaag ggcaccccaa ccatggttat gagccttatt atggtcttgg
     9481 tattcaaaag tcggtgtccc atcataataa gctaaggcat catcgttgat ggtaaagtga
     9541 cctggtaccc agtccacaat aaccccaata ttatgggtat gacactcctc gacaaaatct
     9601 tgaaactcct ctggtcggcc ataagcatgc tctaaagcga agtaacccat aagctgatac
     9661 ccccaactca agcccaaagg atgggacatc aagggcataa actcaatatg agtatagttc
     9721 atttcaacga gataaggaat gagttcatcc ttgagctggg caaaactata aggactgcca
     9781 tcagaatttc ttttccatga tccagcgtga acttcataaa tattgacagg acgctcttca
     9841 aagccccaac gttttcttcg tgccagccaa agtccatcct tccatttctt ctcaggaagc
     9901 tctgttaaga ttgcccctgt tcctggacga gcctcatatc tgacagcaaa agggtcaatc
     9961 ttcatcagtt gatgaccatt ttgacgtgtg acatgatatt tgtaaatatg cccttcttga
    10021 gccatattgg taaagacttc ccagacccca aaatcatttc ttaccattgg aatctgattt
    10081 tcaatccagt tggtaaaatc accaaccaag tgaacagcct gagcattagg tgcccaaaca
    10141 cggaaggtat agccatgctc tccatttagt tcttccctat gtgctcctag ataatgttgg
    10201 agataaaaat tttcacccgt cataaaggtt tttaatgctt ctctattatc catatactcc
    10261 ccttctcctg taagcgtttt ctatgttttt attatactac ctttttagag aagattcaag
    10321 taaattacta tacttcttta attattttga aaatctacaa caagttcact tactcgttca
    10381 attgtaaatc aatatttttt caaaaaattg cgaaaacgcc tttcttttt
//
LOCUS       DAVLZS010000059         9836 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLZS010000059 DAVLZS010000000
VERSION     DAVLZS010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9836
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.059"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(125..841)
                     /locus_tag="VYO88_001754"
     CDS             complement(125..841)
                     /locus_tag="VYO88_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1719808.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            1189..2976
                     /locus_tag="VYO88_001755"
     CDS             1189..2976
                     /locus_tag="VYO88_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1719809.1"
                     /translation="MTRFEIRDDFFLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            2973..3449
                     /locus_tag="VYO88_001756"
     CDS             2973..3449
                     /locus_tag="VYO88_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1719810.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            3477..4382
                     /locus_tag="VYO88_001757"
     CDS             3477..4382
                     /locus_tag="VYO88_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1719811.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            4369..5184
                     /locus_tag="VYO88_001758"
     CDS             4369..5184
                     /locus_tag="VYO88_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1719812.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            5191..5595
                     /locus_tag="VYO88_001759"
     CDS             5191..5595
                     /locus_tag="VYO88_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1719813.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            5848..7014
                     /locus_tag="VYO88_001760"
     CDS             5848..7014
                     /locus_tag="VYO88_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1719814.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            7130..8167
                     /locus_tag="VYO88_001761"
     CDS             7130..8167
                     /locus_tag="VYO88_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1719815.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            8375..9229
                     /locus_tag="VYO88_001762"
     CDS             8375..9229
                     /locus_tag="VYO88_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1719816.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALATQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            9379..9636
                     /locus_tag="VYO88_001763"
     CDS             9379..9636
                     /locus_tag="VYO88_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV1719817.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
BASE COUNT         2821 a         1810 c         2208 g         2997 t
ORIGIN      
        1 tggttctatt tctataaaat attccacaaa ttatagaatc ttcccaaaat aggtaagcgc
       61 tacctttttg gtgtggtata ataagcatag aaaaagcccg agcgattagg ctcaggcttt
      121 cttcttagtg atcacggtca catgagatga atttaatctt gtagtaatca gatcgtttgt
      181 aagtttcact gtattctaaa acttggccag ttgattcgag tttggtgatt ttagtttgta
      241 ggacagtagg gaattgttca tcgactccga ggactgaagc cgcatgttct ggagttggaa
      301 agactatttc gttgatttct tcaaagtgtt catcattcat gtgaatgtgg tagtctaact
      361 tgaaacgatt atagatagaa ctatagtatt caaggtttgg ataatttgcg ttgatatatt
      421 gttctgggat gtaggatgta tggtagatat aaacgacacc gtttgattcg cggatacgtt
      481 caatcttgta gtagaattga tcgccgcgta gacccaattt ttccaagtaa acaagcttgt
      541 ttccgcgttc aattgaaaga acagttacct tatcatcttt agcattgaag agttcaatat
      601 ctgaaaactc tacaagcttg tgtttgcgtg cacgtgaaac gaaggttcct tttccttgtt
      661 ggcggacaat atagccatct ttggcaaggt cgtttaaggc gcgaacaact gtgatagagc
      721 tgacatcgta cattgaaatg agttctgctt cagtgtaaaa tttatctcca ctgctaaact
      781 gcccagagat gattttattt tttaattcgt cttttatgta ttgatatttg ggaattgcca
      841 tatttttacc tctattttcc ttctccatag aaaattttac cataaaagcg aaaaaaatag
      901 tagtcttttg aataaaaaat tagaataata gtttgaaaaa ttaagcgata tagggattgc
      961 tcatatttta taaatgtatt ctatacaaaa ttattttagg tcctatattc cgaatttaaa
     1021 gagcgtttga aatgggtcta aaaatgtttg aaactaattg aatgtgtgta taatagtaaa
     1081 aatgcagtaa atatcccgac aatttctatt gacaattcaa acagattggt ttataattaa
     1141 tataacaaca aatgaaagcg caaactttcg cggtcggaag gtagttttat gacacgattt
     1201 gagatacgag atgatttctt tctcgatgga aaatcattta agattttatc tggtgccatt
     1261 cattatttta gggttcctcc agaggattgg tatcattcgc tctataactt gaaggctctt
     1321 ggttttaata cggtagagac ttatgttgct tggaatttac acgagcctcg tgaaggtgag
     1381 tttcattttg aaggtgatct ggatttagag aaatttctcc aaatagcgca ggatttgggt
     1441 ctctacgcaa ttgtgcgtcc gtctccattt atctgtgcgg aatgggaatt cggtggctta
     1501 ccagcttggc tcttgaccaa gaacatgcga attcgctcat ccgacccagc atatatcgag
     1561 gcagttggtc gctactatga tcagttattg ccaagactgg tgcctcgttt gttggacaat
     1621 ggtggcaata ttctcatgat gcaggttgaa aatgagtatg gttcttacgg agaagataag
     1681 gcttacctga gagcgattcg acagctaatg gaagagtgtg gcgtaacctg tcccctcttt
     1741 acatcagatg gtccatggcg agctactctg aaagctggaa ccttaattga agaggacctc
     1801 tttgtaacag gaaactttgg ttctaaggca ccttacaact tttcgcagat gcaggaattc
     1861 tttgatgaac atggtaagaa atggccactc atgtgtatgg agttctggga tggttggttc
     1921 aatcgctgga aagaaccgat tatcacacgg gatcctaagg aattggcaga tgcagttcga
     1981 gaggttttgg aacaaggctc tatcaatctt tacatgttcc acggtggtac aaactttggt
     2041 ttcatgaatg gttgctcggc tcgaggaact ttggacctgc cacaagttac gtcttatgat
     2101 tacgatgccc ttctggatga agaaggaaat ccaactgcta aatatcttgc agtcaagaag
     2161 atgatggcaa cacatttttc agagtatccg cagttggaac cactctacaa agagagtatg
     2221 gagttggatg ctattccact agttgaaaaa gtttctttgt ttgaaacctt agatagcttg
     2281 tcaagtcctg tagaaagtct ctatcctcaa aagatggagg agctgggaca aagttatggc
     2341 tacctacttt atcgaacaga aacaaactgg gatgcagaag aagaaagact tcgtatcatt
     2401 gatggtcgag atagggccca gctgtatgtc gatggtcagt gggttaaaac tcaatatcag
     2461 acagagattg gggaagatat tttttatcaa ggtaaaaaga aagggctatc taggttagat
     2521 atcttgatag aaaatatggg gcgtgtcaac tatgggcata agttcttagc ggatacgcaa
     2581 cgtaagggaa ttcggacagg ggtctgtaag gatctgcatt tcttactaaa ctggaaacac
     2641 tatccactcc cactagacaa tcctgagaaa attgattttt caaaaggatg gactcaagga
     2701 caaccagcct tttacgctta tgactttaca gtcgaagagc caaaagatac ttacctagac
     2761 ttgtctgagt ttggtaaggg ggttgccttt gtcaatgggc agaatctagg acgtttttgg
     2821 aacgttggcc caactctctc actttatatc cctcatagct atctcaagga aggtgccaac
     2881 cgcatcatta tctttgaaac agaaggtcaa tataaagaag agattcattt aactcgtaaa
     2941 cctacactaa aacatataaa gggggaaaac ttatgacaat tgtaggatgc cgtattgatg
     3001 gacgtttgat ccacggacaa gtagccaatc tttgggctgg aaaactaaat gtttcacgca
     3061 ttatggttgt agacgacgaa gttgtcaaca acgatattga aaagagtggt ttgaaacttg
     3121 cgacaccacc aggtgtgaaa ttgagtattt tgccagttga gaaagctgca gccaatattc
     3181 ttgctggcaa atacgatagc caacgtctct ttatcgtggc tcgtaaacca gaccgcttcc
     3241 ttggtttggt agaagcaggt gtaccacttg aaacccttaa tgttgggaat atgtctcaaa
     3301 caccagaaac tcgttctatt acacgttcta tcaacgtagt agacaaggat gtggaagact
     3361 tccacaaact ggcagaaaaa ggtgttaaac ttactgctca gatggttcca aatgatccaa
     3421 tttcagactt tttgagctta ttaaaatagg aaaaaaattt ttaggaggtc attgttatga
     3481 tacaatggtg gcaaatttta cttctcactt tgtactcagc ttatcaaatc tgtgatgagt
     3541 tgacgatcgt ttcatctgca ggttcccctg tatttgctgg tttcattact ggtttaatca
     3601 tgggagatgt gactactggt ttacttatcg gtggtaactt gcaactgttc gttcttgggg
     3661 ttggtacctt cggtggtgct tctcgtatcg acgcaacttc tggtgcggtt cttgcgacag
     3721 ccttctctgt ttcacaagga attgatgcac cgcttgccat tactacaatc gctgtaccag
     3781 tagcagctct cttgacttac ttcgacgttc ttggtcgtat gactactacc ttcttcgctc
     3841 accgtgtgga tgctgcaatc gaacgctttg actataaagg tattgaacgc aactacttgc
     3901 ttggtgcgat tccgtgggct ctatctcgtg cccttccagt cttctttgcc cttgcttttg
     3961 gtggtgcctt tgtacaatca gtagtagact tcgttgaagc ctacaaatgg gttgcagatg
     4021 gcttgacact tgcaggacgt atgcttccag gtcttggatt tgcaatcttg cttcgttacc
     4081 ttccagttaa acgtaacctt cactaccttg ctatgggatt tggtttgaca gctatgttga
     4141 ctgttcttta ctcatatgta acaggtcttg gtggcgctgt tgctggtatc gtaggtactc
     4201 ttcctgctga agttgctgaa aaaattggtt tcgtgaacaa cttcaaaggt ttgtctatga
     4261 ttggtatttc tatcgtaggt attttccttg cagtgcttca cttcaaaaat agccaaaaag
     4321 tagctgtagc agcaccttct acaccatcag aaagtgggga aatcgaagat gacgaattct
     4381 aattacaaac ttacaaaaga agattttaat caaatcaaca aacgtagctt gtttactttc
     4441 caattaggtt ggaactacga acgtatgcaa gcttctggtt acctttacat gatcttgcct
     4501 cagttgcgta aaatgtatgg tgatggaact cctgaattga aagaaatgat gaaagttcat
     4561 actcaattct tcaatacttc accattcttc cataccatta tcgctggttt tgaccttgcc
     4621 atggaagaaa aagatggtgt aggttcaaaa gacgccgtta acggtatcaa gacaggtttg
     4681 atgggaccat tcgctcctct tggggataca atctttggtt cacttgtacc tgctatcatg
     4741 gggtcagtcg cagcaactat ggctatcgct ggccaacctt gggggatctt cctttggatt
     4801 gcagttgcag tagcgtatga catcttccgt tggaaacagt tggaatttgc ttacaaagaa
     4861 ggggttaacc ttatcaacaa catgcaaagt accttgacag ctttgattga cgctgcatct
     4921 gtacttggtg tcttcatgat gggtgctctt gtagcaacag tgattaactt tgaaatttct
     4981 tacaagttgc caatcggtga aaagatgatt gatttccaag acatcttgaa ccaaatcttc
     5041 ccacgtttgc ttccagcaat ctttactgcc tttatcttct ggttgcttgg taagaaaggt
     5101 atgaactcta ctaaagctat cggtattatt atcgtacttg ctttggctct ttctgccctt
     5161 ggtcactttg cacttggaat gtaattcctt atgactaaat cattaatttt ggtgagccat
     5221 ggtcgcttct gtgaggagct tagaggtagc acagaaatga ttatgggccc acaagacaac
     5281 atttacacag tagctcttct tccagaagat ggcccagaag aatttactgc taaatttgaa
     5341 gctgttattg aaggattgga tgatttccta gtttttgcgg atcttctcgg tgggacacct
     5401 tgtaatgtgg tgagtcgctt gatcatggaa ggtcgtgata ttgaccttta cgcagggatg
     5461 aatcttccaa tggtgattga atttatcaat gcgagcctta caggcgcaga tgcggactac
     5521 aagagccgtg ctgcagaaag cattgtgaaa gttaatgacc tgttagcggg cttcgatgat
     5581 gacgaagatg aataatactc ttcgaaaatc tcttcaaact acgtcaacgt cgccttactg
     5641 taggtatatg ttactgactt cgtcagtctt atccggcaac ctcaaagcag tgctttgagc
     5701 agcctgcggc tagtttccta cagattttag ttggaactcg attcaattca tgtgacaacg
     5761 tgaaaatcgt tagagcattt tatatagaat atacatggga atggagctta ctcccattcc
     5821 tatatttaat agaaaaagag gaactcaatg ctacattata caaaagaaga cttgctcgaa
     5881 ttgggtgcag aaatcactac gcgtgaaatc taccaacagc ctgatgtatg gagagaagct
     5941 tttgaatttt atcaagcaaa acgtgaagaa attgcagcct tcctacaaga aatcgctgat
     6001 aaacatgact atattaaggt tatcttgaca ggtgctggga cttctgctta tgtgggagac
     6061 accttgctac cttactttaa ggaagtctat gacgaacgca aatggaattt caatgctatt
     6121 gcgacaacag atatcgttgc caatccagca acctatttga aaaaagatgt ggcaactgtc
     6181 cttgtgtctt ttgctcgtag tgggaactcg cctgaaagtg tggcgactgt tgatttggcc
     6241 aaatccttgg tggatgagct ttatcaagtg acgattactt gtgcagcaga tggtaaattg
     6301 gctcttcaag ctcacggtga tgaccgtaat ctcttgctct tgcaaccagc tgtctctaat
     6361 gatgctggat ttgccatgac ttctagcttt acgtctatga tgttgacagc tctcttggtc
     6421 tttgatccta cagaatttgc tgttaagtct gaacgttttg aagttgtatc tagtcttgcc
     6481 cgtaaagttt tagacaaggc agaagatgtc aaagagctcg ttgatttaga ctttaaccgt
     6541 gtcatctatc taggcgctgg tcctttcttt ggacttgctc atgaagctca gctcaagatt
     6601 ttggaattaa ctgctggtca agttgcgacc atgtatgaaa gcccagttgg cttccgtcac
     6661 ggtccaaaat ctcttatcaa cgacaataca gttgttttgg tctttggtac aacgacagac
     6721 tacactcgta agtacgactt ggacttggtt cgtgaagttg ctggtgacca gattgctcgt
     6781 cgtgttgtgc ttttgagtga tcaagctttt ggtcttgaaa atgtcaaaga agtggccctt
     6841 ggttgtggcg gtgtcttgaa tgatatttac cgtgtcttcc cttacatcgt ttatgcccaa
     6901 ctctttgccc tattgacttc actcaaggta gaaaataaac cagatacacc gtctcctaca
     6961 ggtacagtaa accgtgtagt acaaggtgtc ataattcacg aatatcaaaa gtaagacagt
     7021 gtttatgaat tcttgacaag aggatttgta aattatcaga taaaccatag attgtcagta
     7081 cgctttctat ggtttgtttg cttgagagaa atagtaaaag gagaacagaa tgaaagcata
     7141 cacagagcgt gtatttggaa atgttgaggg cgaggatgtc ttggcctatc gatttgagac
     7201 agacggtggc taccaacttg aggttatgac ttatggtgcg accatcttgc gctatgtcgc
     7261 acctgacaag gctggaaatt ttgccaatgt tatcttggga tttgatgact ttgatagtta
     7321 tgtaggcaat agtcccaagc atggagcaag tgtaggtcct gtagcgggtc gtattgcagg
     7381 tgcgaccttt gagctcaatg gtaagaccta tgaccttgag gttaataatg ctagcaactg
     7441 taatcacagt ggttcaactg gttgggattc cagcttgttt gaagttgaag aagtaagcga
     7501 tcatggcttg actctctaca cagagcgtac agatgggaca ggagggttcc ctggaaatct
     7561 caagatttgg atcagttatc acttggaaga aactggtgcc tatgaaatca gctacaaggt
     7621 aacgaccgat caggatacgc tggtcaatcc aaccaaccac agctatttca acttgtctgg
     7681 tgatttcacg cagacgattg accgtcatgt cttccaacta aacacagagg gcatttactc
     7741 aatcgctcct gacggtgttc ctgccaaaac tccagaagcc aaccgtgatg tggtcaaaca
     7801 catctacaat ggtaccttgt tgaaggatat ctttgcagaa gaagatgagc aaatccagct
     7861 ggcatcaggt ttggatcacc catttgccct tcctgtaggc catgacaatg ctggattcct
     7921 ttatgaccaa aattcaggtc gcttcctgct tttcaagaca gaagctcctt gctttgtggt
     7981 ctacacagca aactttgtgg atgaaagtgt catcatagga ggtcagccaa tgctacagca
     8041 caatgggatt gctcttgaag cacaagcttt accagatgcc attcacagtg accttaaagg
     8101 ccaagtcatt cttaaagctg gtcaaacctt caccagtaag acacgttatg aacttgttgt
     8161 gaaataaaaa aagctggtca aaaagtcttt aaaattaaaa taatgcatat tgtcaggtga
     8221 tggaaagttt gataatatgc gttttattat aaaatgattt actttatctt atcctgaaat
     8281 ggtgttattt ttgagttatc tggcttgact ttcttgatga aaattatata atagttgtaa
     8341 caataataat tacaacgaga aaagaggacc atttatgacc tatgaataca agagtcacat
     8401 ttatttggca gagacagctt taaatgtaaa ggatttggcc agtcaaacag ccttttatca
     8461 gcaagttatt ggtttagaaa tcttatctca aactgagaca gagtccattc taggccttgg
     8521 tggaaaagtc ttggtacagc tgattcaagc acaagagagc ggagaagtga gggaacatta
     8581 tggtctttac catttggcca ttctcttgcc cacacgcaag gctttggctg atgtcttgaa
     8641 acacctgaca gatttacaga ttcctcttgt cggcggtgca gaccatggtt acagtgaagc
     8701 tatttacttg gaagatttgg agggaaatgg cattgaactc tatcgagata agccagtttc
     8761 cacatgggat attcgagaag atggacgcat tatcggagtg acagaggctc ttgcgacgca
     8821 ggacatttat gagttggggg aaagagtaga gccctttatc ctggcagaag gtacgagaat
     8881 ggggcatatt catctttccg tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt
     8941 gttagggcta gaggataaat tcagtgtgcc tagcgctagt tggattgcgg ctggagatta
     9001 ccatcatcat ttagcagtta acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg
     9061 cttaccaggt ttagcctact atgtcatcga agtcgcacat aaaaaagaac tattaacgat
     9121 tgcccaacga gcacaagaag ttgacgcacc aatcaaatgg atgacatcga gccaattgga
     9181 aatcacagac tcagatggca tcgtgacccg tattcgttta gcaaggtaaa attaggaatt
     9241 tttaataagt tataagtatt gctagtttgc tttttgaacg gtctttggta acagaactgc
     9301 gtgagctgga tgggcgagaa ttttgacaaa gaagctgatt agagatataa tgaagaaaaa
     9361 tcgagcaagg aaaaagaaat gacaaattca aagtatatta cttgtttgaa acgttcagag
     9421 ggccagttgt gtgggattca aaagatgatt gaaggagatc gtgactgtgc tgatattgtg
     9481 acgcaactga cagcagtgag atctagtgta gagcgcgtga ttgagatgat aattaccgaa
     9541 aatcttactg aatgtatcaa tcagccacta gatgattctg aagctcaaaa ggaacgccta
     9601 gaaaaggcta tccgatactt gattaaacgg aaataaatga atgttttgag acgatatgtg
     9661 caaaggtcta ttaactatta gaatagttta atgtgagtca aaagaagttg taaaaaatct
     9721 ttaaaattaa aaaaacgcat agtatcaggt gttgaatgta ctgaccccaa aaagttagat
     9781 tttttctgtc taacttttgg ggtgcagttc ataagaacct tggtaatatg cgtttt
//
LOCUS       DAVLZS010000060         9811 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLZS010000060 DAVLZS010000000
VERSION     DAVLZS010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.060"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            65..331
                     /locus_tag="VYO88_001764"
     CDS             65..331
                     /locus_tag="VYO88_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1719818.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYFRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            341..1678
                     /locus_tag="VYO88_001765"
     CDS             341..1678
                     /locus_tag="VYO88_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1719819.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            1922..2614
                     /locus_tag="VYO88_001766"
     CDS             1922..2614
                     /locus_tag="VYO88_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1719820.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(2717..4369)
                     /locus_tag="VYO88_001767"
                     /pseudo
     CDS             complement(2717..4369)
                     /locus_tag="VYO88_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(4419..5450)
                     /locus_tag="VYO88_001768"
                     /pseudo
     CDS             complement(4419..5450)
                     /locus_tag="VYO88_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(5463..5912)
                     /locus_tag="VYO88_001769"
     CDS             complement(5463..5912)
                     /locus_tag="VYO88_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1719821.1"
                     /translation="MCTILVSIHYKIGLSLSGVYKAVVDGEMAVGLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKAKNMENAKKFIDFIISQEVQDTLGTTTTNRPVR
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            complement(5988..6584)
                     /locus_tag="VYO88_001770"
                     /pseudo
     CDS             complement(5988..6584)
                     /locus_tag="VYO88_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(6801..6998)
                     /locus_tag="VYO88_001771"
     CDS             complement(6801..6998)
                     /locus_tag="VYO88_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1719822.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSSLSDISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(7073..7849)
                     /locus_tag="VYO88_001772"
     CDS             complement(7073..7849)
                     /locus_tag="VYO88_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV1719823.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            7971..8717
                     /locus_tag="VYO88_001773"
     CDS             7971..8717
                     /locus_tag="VYO88_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1719824.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNMATLENAGIMVKVVS"
     gene            8730..9710
                     /locus_tag="VYO88_001774"
     CDS             8730..9710
                     /locus_tag="VYO88_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1719825.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
BASE COUNT         3095 a         1525 c         2065 g         3126 t
ORIGIN      
        1 ctatttgaaa agaatcctgt ttaatgttaa ggtttcttat tttaagaaga attggagttt
       61 acttatgaaa gccattataa ctgttgttgg taaagataaa tctggaattg ttgcaggtgt
      121 ttctggtaaa attgcagaat taggattgaa tattgacgat atctctcaaa ctgtcttaga
      181 tgaatatttt acgatgatgg ctgttgtatc tagtgatgaa aagcaagatt ttacctattt
      241 tcgtaatgaa tttgaagctt ttgggcaaac tttgaatgta aaaatcaata ttcagagtgc
      301 agcgattttc gaagctatgt ataatatcta ggaggttatc atggatatta gacaagttac
      361 tgaaaccatc gccatgattg aggagcaaaa tttcgatatc agaaccatta ccatggggat
      421 ttctcttttg gactgtatcg atccagatat caatcgtgct gcggagaaaa tctatcaaaa
      481 aattacgaca aaggcggcta atttagtagc tgttggtgat gaaattgcgg ctgagttggg
      541 aattcctatc gttaataagc gtgtatcggt gacacctatt tctctgattg gggcagcgac
      601 agatgcgacg gactacgtgg ttctggcaaa agcgcttgat aaggctgcga aagagattgg
      661 tgtggacttt attggtggtt tttctgcctt agtacaaaaa ggttatcaaa agggagatga
      721 gattctcatc aattccattc ctcgcgcttt ggctgagacg gataaggtct gctcgtcagt
      781 caatatcggc tcaaccaagt ctggtattaa tatgacggct gtggcagata tgggacgaat
      841 tatcaaggaa acagcaaatc tttcagatat gggagtggcc aagttggttg tattcgctaa
      901 tgctgttgag gacaatccat ttatggcggg tgcctttcat ggtgttgggg aagcagatgt
      961 tatcatcaat gtcggagttt ctggtcctgg tgttgtgaaa cgtgctttgg aaaaagttcg
     1021 tggacagagc tttgatgtag tagccgaaac agttaagaaa actgccttta aaatcactcg
     1081 tatcggtcaa ttggttggtc aaatggccag tgagagactg ggtgtggagt ttggtattgt
     1141 ggacttgagt ttggcaccaa cccctgcggt tggagactct gtggcacgtg tccttgagga
     1201 aatggggcta gaaacagttg gcacgcatgg aacgacggct gccttggccc tcttgaacga
     1261 ccaagttaaa aagggtggag tgatggcctg caaccaagtc ggtggtttat ctggcgcctt
     1321 tatccctgtt tctgaggatg aaggaatgat tgctgcagtg caaaatggct ctcttaattt
     1381 agaaaaacta gaagctatga cggctatctg ttctgttgga ttggatatga ttgccatccc
     1441 agaagatacg cctgctgaaa ccattgcggc tatgattgcg gatgaagcag caatcggtgt
     1501 tatcaacatg aaaacaacag ctgttcgtat cattcccaaa ggaaaagaag gcgatatgat
     1561 tgagtttggt ggtctattag gaactgcacc cgttatgagg gttaatgggg cttcgtctgt
     1621 cgacttcatc tctcgcggtg gacaaatccc agcaccaatt catagtttta aaaattaaga
     1681 aaataggaga aattttaagt tctatttaag attagatgtg tatactataa tcattaaata
     1741 aagacctcct aatattattt gaaacagata acactgaatt agtttgaatt tgattttcat
     1801 ctaatatctt tatttaatga actcctaaac tttttcataa taatctcctt caaaagtcgc
     1861 ctgtatgggt ggcttttatt ttatcattca tgatataata gaagcaaacg gaggacggaa
     1921 aatggtaaaa gtacgattgt atttggtacg tcatggcaag accatgttta acacgattgg
     1981 tcgcgcgcaa ggttggagcg atactccctt aactgctgaa ggtgaacgag ggattcaaga
     2041 gttaggaatc ggtttgcgag aatctgatct acagtttgag cgcgcttatt cgagtgattc
     2101 tggtcgtacc attcagacca tgggaattat acttgaagaa cttggcttgc aggggaaaat
     2161 cccttatcgc atggacaagc gtatcagaga atggtgtttc ggtagttttg atggagccta
     2221 tgatggtgat cttttcatgg gcattattcc tcgtatcttt aatgtggacc acgttcacca
     2281 attgtcttat gctgaactgg ctgagggctt ggtagaggtc gatacagctg gttgggctga
     2341 aggttgggaa aaactcagtg gccgaatcaa ggaaggcttt gaaataattg caaaagaaat
     2401 ggaagatcaa ggtggaggta acgcccttgt tgtcagccat ggaatgacta ttggaaccat
     2461 tgtttatctg attaatggca tgcatccgca tggtctagat aatggtagcg tgacgattct
     2521 tgaatatgag gacggtcagt ttagggttga agttgtcggt gaccgtagtt accgagagct
     2581 aggacgtgag aagatggaag aaggctctat ttaatcagtc tagacttgct tgccatgagc
     2641 tagggatttg ataagaatat caagataaga aaaaacagcc gagggtactc ctttcggctg
     2701 tttttgatgt ggaaaactaa agtgtaatgc tattgctttt agagattttc ataaacaaga
     2761 gcaaggaacc tactgttaga acagtcagga tagttgacaa ggctgcggct acaccgtaat
     2821 ttcctctgag aacctctgta taaatagcta cagtcattgt tcttgttttg acattgtaga
     2881 ggaggataga ggatagaagt agagagttct gaaatcagtg tgacccaaga taggatggct
     2941 ccagaaataa tacccgatag catcattgga gttgtaatct tagcaaaggt attgagacga
     3001 ctacttccta agctttcagc agcttcttca atacttggtg ctatttgttg taagctagca
     3061 acagatgagc gaatagtata cggtaatctt ctgacagata gagacataat caagatgaaa
     3121 gcagtccctg taatcataag aaatccactt ccaaatagac cagtattgaa ggaagaaatg
     3181 aaggcaatcc ctagaacggt tcctggtaca atataaggta ccatactgag gctgtcaatt
     3241 aagtttgtaa acaaattccg ttttctaacg gctaggtagg agataaatgt cgcaaataga
     3301 acaactagaa ctaaggcaat caaagggata cgaatggtat tgaaaatagc agatcccata
     3361 cgattgaaag ctagcttgta actgtttgga gaataatctt taaaaaatac catacctgat
     3421 gtttttagga aagaggtata aattaagtag atttgaggta aaacagagat aaagataatt
     3481 ccgtagactg ttgcataaat ggcagccatt tttccttttg tagttttttt aggctcaatt
     3541 ggatggagca gattcatgct gaaactgtag cggtttgcaa tgtgtttttg gataaggaaa
     3601 attgccaagg caatgataat cgccataatt gcaaaagcag aatttcctcc aacctcgcta
     3661 ataaattggg tataaatcag gacagggaaa gtccgatatc cttcgccaat caacataggc
     3721 gttccaaagt ctgagaatgc tctcataaat acaagcaagg agctgctagt aaggttggaa
     3781 ctagaagagg taaaacaacc gttacgatag gtttaaatcc gaaggacccc atgctttcag
     3841 ctgcttcaag tagagaattg tcaatactgt tcattgttcc agcaacatat agaaatacca
     3901 gtgggaatag ttgcagtgta aagacaagta caattccttt gaatccataa atatcgatag
     3961 ctggaagatg aagggcattt gtcaaaaatt tagtgatgac cccatttcgt cccagcaaga
     4021 gaacccagga gtaggctcct acgaaaggag ctgacatgga agcaatgata atcaatattt
     4081 gtagaaattt cttccccttg aagtcataca tagagaagag ataagctaat agggttccta
     4141 caactaagga agtgacagta gcggtaatgg aaaccctgaa actgttgact agtgtctcag
     4201 agtagtaggt tttactaaag aaagtgacaa aattagctag tgagaattgt ccttcatgta
     4261 taagtgctta cttgagcacg gtaacgatag gataaacgag aaagacaaga taggtaagaa
     4321 agatgaagaa agaggaggct gcccaaatat ttagtttttt acattccatg gttgactcct
     4381 tttatcaggt tttgggaacc atctgcagaa aagatgtttc atttttgcgt attgattcgt
     4441 agacgaagac gattgccttt ttgtagatct tcttcaaaag ttgattcttc actaacttga
     4501 atttttgagg caaaacctgt ctcaatgaaa tactccgtat ttagtccaag atagacgcta
     4561 tcgctaatag ttccttcaat atctccagat tcatctttga taaactcttc gggacgaatg
     4621 cttacatgaa tagcttgctc ctcaacctga tcaagagctg gcattcgaag ggcatagcca
     4681 tctgaaaaga cgatataagc gccgtcgctc cgtttttcaa gattggcagg gataatattt
     4741 gtgcgtccga taaaggttgc cacaaactca ttagctggtt tatgatagag ttcttttggt
     4801 cggccgattt gttggatcac cccatctttc ataacagcaa tttggtctga aatagccatg
     4861 gcttcttctt ggtcgtgggt tacataaaca gttgtaattc ccacttcgtg ttggatttct
     4921 cggatggctt gacgcatatc caagcgaagt ttggcctcca gattactaag tggctcgtcc
     4981 atgaggagaa cacttggatt aaccgctaag gcgcatgcca aggtgacacg ttgttgttgt
     5041 ccaccactga gtttatcggg ctttcaatcc gcatattgag caatttgcat gagttcaaga
     5101 tacttgttgg tctgttgaat caattcttct tttggaacct tcttttgcat aagaccaaaa
     5161 gcaacgttgt ctcggacagt caaatgtggg aaaatagcgt agttttggaa aaccagcccg
     5221 atattgcgtt tgctgggttc catattattg atttttgtat catcgaagta aaattctcca
     5281 tctttgatac tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc acatcctgaa
     5341 gctccaagaa gggtaaagag acttcctttt ggaattgtaa tgttcaaatt ctcaataaca
     5401 gggacatcgt ggtagatttt tttggcgtta ataatttcga tctcactcat agtgaacctc
     5461 ttttactgtt tagattggat atctgtaaag acttcgttgt atttcttaac gatatctgat
     5521 ttattcttga tgacataatc ataatcttca gtgagtgttt tgattttgtc aattggtttc
     5581 atgttttcgc ttgttttagc atttttacga acaggacggt tagtagtggt tgtaccaagt
     5641 gtatcttgta cttcttgaga gataataaaa tcgataaatt tcttggcatt ttccatattt
     5701 ttagcttttt taacgatagc agcactagca ggtaggaaga cggttccttc ttttggatag
     5761 actaccttaa tgttagctcc gtcatttaag agtttaactg ctggatcctc ataagagaga
     5821 ccaacagcca tttctccatc aacgactgct ttatagacac cagataaact taaaccgatt
     5881 ttatagtgta ttgaaactag aatagtacac atctacttct aaaatattgt tagaaatcga
     5941 tttgaatgtc ctgattaatt tgtcctgttc ttatttcatt ttattatacc atcaataagt
     6001 gtgaaaagat cttttacata agaccaagcc ttatcatctt tgtaaccacc ttgagcttgt
     6061 agcatatttg ttaattgagc aaaggcgcta gaagagtttg ctgggtcagc agttgcgatt
     6121 tttcctttta gttcaggttt gagaaggtcg ctatatcctt cgatgttcat gcctttagtt
     6181 aaatcagggt ggacgattaa aacattacca tctagtgtat aaggagtaga gaagccagtt
     6241 gtgttttgat attctttgat aacattatca ttttcttttg aaatatagtt ttcaaagagt
     6301 tctccgtggg tagcatattg tgtataagaa ccaccaaaga taacatcagc tacaggaact
     6361 tctttttctg actctagttt tttgaaaagt tctccagtac cagcttgaat cagttctatt
     6421 ttgataccat atttttcttc aaaggcagga atagttgctc caattaagcc ttctgagttt
     6481 ggtcaataaa cgactagcga accaccgtct cctttatcag atgaactgtc atcggcagat
     6541 tcattagaag aacaagcagc ataatacatc catttctttt tcatgatgga tacctccgtt
     6601 gtgttattta agtttatttt aaaacaatgt aagcgttttt aaaacctaca attctattct
     6661 atagtgtatt gaatctataa cagtacactt tgactgctaa aatatttcta taaattaatt
     6721 tgactttcct gatagagatg ttcacatctt atttcaattc actatattag agtaaaattc
     6781 tctacaaaaa gaagaatagc ctattttact attcttccga gtgatttcaa tttctttggg
     6841 gaaatatgga gatacttttt aaatactttg gcaaaatatt tatagtctga aaatccaact
     6901 tggtcagaga tatcgcttaa agaggagttg ggagattcag ccatcttatc tatagcttgt
     6961 ttcaggcgat attgtaagat atattcattt agagtcatgg ggaagtcttc tttgataacc
     7021 ttatatagat gcttgttatc tgcaaatagc tagagcattt caaggaaata aactagaaat
     7081 aacaattaat atggtggttc agaaatacct tttgataatc aataagatct tcaggatgaa
     7141 gtgcgttgac tccatccatt tcatatttcc gatttaataa acgatatttg ttttcaccaa
     7201 attgatgaaa agggagtagt tgaacttggt cgatatttaa tgagttaaat agagtagcga
     7261 atttttctgc atcctctaaa ctattgttaa aattaggaat aactgggatt cttaaaacga
     7321 tagttttatt ttgagaaaaa gcataatgaa tgtttttaat aatcatttga ttaaaaaccc
     7381 cagtcacttt tttatgtttt atagaattat aatgttttag gtctgtgtag ataaaatcca
     7441 catattgaat taaatcaata aatttttcat gatcaacaaa ggcagtagtt tcaatggcag
     7501 tgtgtatgtg atgttcttta gctgatttta agatggcttt agcaaattca aactgagcaa
     7561 atatttcacc tcctgataaa gttaaacctc caccggattc ttcgtaaaat tctttgtctt
     7621 ttaatacctc tgtaataatt tcttctacag tcttttcttc accgactaag gtgaatttct
     7681 ctcgttgagc atctttcatt ttttcaggtt tcattctttg agattcagga ttagaacacc
     7741 atggacagcg cagaggacat ccttttaaaa aaacagttgt acgaataccc ggaccgtcat
     7801 gaattgaaaa gtgttgaata ttaaaaataa ttcctttaga tatttccata agagttcctc
     7861 ctcttcataa gtctatccta tcacaaaaac gaaagaaaaa caattacgaa cgaaaggtta
     7921 atttgttgtt ttttgctttt tattttggta gaataaaacg gaggtgtaaa atgaaaagat
     7981 tggaacaaat tattaaatta gtatcagaat atgaaaagat cgacgttaat acattatcgg
     8041 aaaaattaaa tgtatcgaaa gtaacgatta gaaaagattt agataaatta gagtcaaaag
     8101 gtttattaca cagagagcat ggatatgctg tattaaatag tggagatgac ttaaatgtac
     8161 gtttgtcaat taactatgaa attaagagaa aaattgttca ggaagcagta aaattggtgt
     8221 cagataatga aacaataatg atagaatctg gatcgacctg tgctttactt gctgaggaaa
     8281 tttgcaagca aaaaagaaat gttacgattg taacaaattc attttttata gcaaattttg
     8341 tgagagctta tgattcatgt cgtattattg ttcttggtgg agagtttcag aaggattcac
     8401 aggttactgt gggaccttta ttaaaagaaa tgatacagac ttttcatgtg cgtcaagctt
     8461 ttgttgggac agatggctac gataaagaga tgggctttac aggaaaagat ttaatgcgca
     8521 gtgaggtagt tcaatatatt tcagcagcgt cggataaagt cattgtgcta actgactcaa
     8581 gtaaatttga taaaaggggt acagtaagaa gatttgcttt aagtcaagtc tatgaagtaa
     8641 taacagacga aaaactttct aaacaaaata tggctacatt agaaaatgct gggataatgg
     8701 ttaaggtagt ttcgtaagag gttaagtgta tgaatcaaga taggaataaa ctgctctcta
     8761 aaattgctta tctgtattat attgaaaact taaatcagtc acaaatagca gcaaaattag
     8821 gaatttatag aacctctatt agtagaatgt taacagaagc aaggaatgca ggaattgtta
     8881 aaattgaaat agagaatttt gataccaata tgtttaagtt ggaaaattat gtaaaagaaa
     8941 aatatggtct ggaaagttta gaaattattc caaatgaatt tgatgataat ccaacaattt
     9001 tatctgaaag aatttctcaa gttgcagcag gtgtccttag gaatctaatt gatgataata
     9061 tgaaaattgg cttttcttgg gggaaaagtt taagtaattt agtagattta attcacagta
     9121 aaagtgtccg aaatgttcac ttctatcctc tagcaggtgg tcctagtcac atacacgcta
     9181 aataccatgt gaatacactg atttatgaaa tgtctagaaa atttcatgga gagtgtacat
     9241 ttatgaatgc aacgattgtg caagaaaata aattgttagc agatggtatt ttgcaatcaa
     9301 gatattttga aaatttgaaa aatagttgga aagatttaga tatagctgta gtcggaattg
     9361 gtgattttag caataaagga aagcatcaat ggttagacat gcttacagag gatgacttta
     9421 aagaattgac caaagttaaa actgtaggag aaatttgttg tcgatttttt gattcaaaag
     9481 gtaaagaagt ctatgaaaac ttacaggaaa gaacgatagc aatctctttg gaagatttaa
     9541 aaaatattcc tcaaagttta gctgttgctt acggtgatac gaaagtatct tcgattcttt
     9601 ctgtcttgcg tgctaattta gtaaatcatt tgattacaga taaaaataca attttaaaag
     9661 ttttggaaga agatggggat ttgactttta gagagattct aggtgagtga aaatgataga
     9721 ctgatcagtt tatcgttttt tctttttagt cgattgcaca tttgtgctca tataaacaaa
     9781 aatagtttat ctgttgtttt tggattgaca a
//
LOCUS       DAVLZS010000061         9793 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLZS010000061 DAVLZS010000000
VERSION     DAVLZS010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.061"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(1..456)
                     /locus_tag="VYO88_001775"
     CDS             complement(1..456)
                     /locus_tag="VYO88_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719826.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(731..2470)
                     /locus_tag="VYO88_001776"
                     /pseudo
     CDS             complement(731..2470)
                     /locus_tag="VYO88_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(2633..3517)
                     /locus_tag="VYO88_001777"
     CDS             complement(2633..3517)
                     /locus_tag="VYO88_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1719827.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVDTENGNYVGEASHVLVLLTNYFADKKIFEENKDDYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(3629..4483)
                     /locus_tag="VYO88_001778"
     CDS             complement(3629..4483)
                     /locus_tag="VYO88_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1719828.1"
                     /translation="MLGVIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     TWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(4541..5299)
                     /locus_tag="VYO88_001779"
     CDS             complement(4541..5299)
                     /locus_tag="VYO88_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1719829.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(5361..5549)
                     /locus_tag="VYO88_001780"
     CDS             complement(5361..5549)
                     /locus_tag="VYO88_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1719830.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(5871..6437)
                     /locus_tag="VYO88_001781"
     CDS             complement(5871..6437)
                     /locus_tag="VYO88_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719831.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(6705..8384)
                     /locus_tag="VYO88_001782"
     CDS             complement(6705..8384)
                     /locus_tag="VYO88_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1719832.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            complement(8476..8637)
                     /locus_tag="VYO88_001783"
     CDS             complement(8476..8637)
                     /locus_tag="VYO88_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719833.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(9321..9635)
                     /locus_tag="VYO88_001784"
     CDS             complement(9321..9635)
                     /locus_tag="VYO88_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719834.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(9601..>9793)
                     /locus_tag="VYO88_001785"
     CDS             complement(9601..>9793)
                     /locus_tag="VYO88_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV1719835.1"
                     /translation="KLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTVLPDIKIKL
                     PIDSRGTPDWNYMERYRDR"
BASE COUNT         2873 a         2041 c         1355 g         3524 t
ORIGIN      
        1 ctaaaagtaa gattccattg tatttccttg ttggtctttc atatcacgaa ttttattttt
       61 cagaatatta aagttacaaa tttcatctct aatatcgtta tccgctctgt agccattaat
      121 catctcagtc agagttttcc ctttactacc attctttata gtagtattta ctctttttat
      181 actgctttca aaaggctcat atgttttata cttaattact tcgtctttaa aattaaataa
      241 aggtgtatcc ggcttagcat tccataaaat aatcaaccac attataacat tataaagctg
      301 ctttgcagtt tcattccact tttcaggttg taaatttcca ctccctgtat tgtcatattc
      361 ttgtctatta tttacatgag aatcacctac aagcggatta aaaagaggta gccctttgtg
      421 attaattagt tctaaaaaat cccttgccgc acccatgcaa cactgaataa cttccttctt
      481 gccatcaatt ttactctcag cgataaatac ataatattca tcttcaatag ttgctcctgc
      541 atcactatgt ttttgttgat ttgctaacag cttaatatgt gctttaggct aaacttcaaa
      601 atctctaaca attctttgtc ttgtttcatg tcctctacaa ttcatttaag ttctccttta
      661 caagtttagt aactagcctt attatactat ataagatatg aaatgtacca taatcttcat
      721 caactagttt ttagaaaatc acaaatccat ctggagagat gacaagctga ttctccaatt
      781 cttggcaatt gcttgctagt gctactgctt ctttctctaa aagataatct tctgttgatt
      841 ggttgaatat tgctttgagg atccgtcctt cgtatttcca ttccagagct actagatcag
      901 atttgatttc ttgaaggcta tacttgccat gcgaaatgat tactgacgcg tatttccgaa
      961 tcttaatcag cctcttcata aagttcagca tatcattgtc acttgataca cgttcccaag
     1021 gcatacaacg acgacaatct ggatctggtc ctccagtcaa ggctagctcg gttccgtaat
     1081 aaatgcacgg tgttcctttt tgtaaaaaga gaaaggctaa ggctgattta accagttgaa
     1141 catcttcatt ggccgtccac aggattcgct ctgtatcatg tgaatccaag agattaaaca
     1201 tgacctctga aatctgctgc ttgtaataca tagactctcc attgatttca tcgatgaact
     1261 ggtctgtctt cttaattcct cgtaagaaat agtccttgat actatcagat aaaggataat
     1321 tcatgacggc atggaactca tctccattta gccaaggctg agatgtatgc cagacttctc
     1381 ctaggatata aagatcagga tttttagcta aaactgcctt acgaaaatcc ttccagaact
     1441 gatggtcaat ctcattagcc acatccaaac gccaagcatc gatattaaac tcttcaatcc
     1501 aataagtcgc aacctttaaa agataattct tgacctctgg attggctgta tttagcttag
     1561 gcatatagtc ctcgaaacca aaaacatgat agggtaagtc tctcttatta actagttttt
     1621 cagttgtcac tgggaattgt tgaatatgga accaatcctt ataagcagac tgttcaccat
     1681 ttttgacgac attttttcat tgaagagatt gcgaaccaat atgattaaat accgcatcca
     1741 gcatgacttt catgccacga tgatgcgctt gatccaccag ttcccgaaag gtctccttgt
     1801 ctccaaaatg acggtcaatt tcaaagtaat ctgtcgtatt gtacttgtga ttgcttgtag
     1861 attcaaagat gggacaaaga tatagtccag taatacccaa gtcttgcaag taatccatat
     1921 gatcaataat cccctgtaaa tcaccaccaa agaaatcatc gctcttaggt gtgacagatg
     1981 aatcccagtc taaagtccct tctgggttta atagagcatt gccattggca aatctttcag
     2041 gaaatatctg ataccatacc gtatttgaaa ccccgtcagg aaccttgcag gcatcaatct
     2101 catgaagata aggcaactta aatccattcc caattgcatg aagattttct agagaatttt
     2161 ccacacaccc tttatcgcca tacaaaatat tttgaccttc tgtatctctg agctcaaaga
     2221 gatactggat acgtgcaaag tcaactgaca cttcaacctg ccaatagtca aataaggtac
     2281 cagaagttat cttgaccatt tcttttgtat cctgataaaa ctcctccata aagataaaag
     2341 ggtccccata gtgcaagttg atgctttcaa tgtccccttt cttagttcga attcgaatat
     2401 ggagtttctt atccttataa agataggcat actccgactc aggcctatgg taaatagcac
     2461 tcaattccat caatttgtct cctaaagtat tcattcaaat tttacgcaaa cgttttcaaa
     2521 ctcaataaat ccagtatact atttttgtaa actatttgca aggaatgtcc gttgttaaag
     2581 gaactatctt ttaaagtata caaaaagcct taaaaaaggc tttctctata tactaatcct
     2641 ctttcggttt tgaaaatact tctactcgct gagctaggac tttgatttct acaggtaggt
     2701 tatctgattt atctccgtca acatctgact ccaattcact atctgaagag attttaatat
     2761 tacgcgcttt gatatactcg atattatcat ttgcgacaac atcccctttt aataaatcag
     2821 gaatgacgga taatttggag aatatagagg catctttcag aatcaaaatg ttggcatagt
     2881 cgtccttgtt ttcttcaaag attttcttat cagcgaagta atttgtcaaa aggaccaaaa
     2941 catggctagc ttcaccaaca taatttccat tttctgtatc aaccttaatg ttaaagacct
     3001 gatctgtcat gacagacttc atggtattta cagcataggt taaaataccg aattttgttt
     3061 tgtcctctat ttcaacattg tgaatcgcct caggcagaga accgatacta aagatataac
     3121 caaaatagtt gtcatttgct ttaccgatat caatcttatt ggttaaatca aaatccagtt
     3181 cgtcaattgc gccatcgatg tcttgattga tttccaaaag ttttgtaatg aggttacccg
     3241 taccgcctgg gataatccct aacttaggaa tgtagtctct ctcatcaata cctgaaatga
     3301 cttcattgac agttccatct ccaccaaaca caaccactgc atcatactgc tcacgagaag
     3361 cttcttcagc aaaatgtgtt gcatccagcg ctttttcggt aattttggtt tcaacatatt
     3421 caaagtattc ttttgcttta ttctccagct tttctttgta atccaaagcc ttctcgccac
     3481 cagaagtagg gttgataatt accattgctt ttttcattga ttttatcctt aattttaaac
     3541 agaaatgttt acatttcgtc gtatgcaagt aaatgtaatc ctattataca atgaaaatac
     3601 agaaaagaga aatctgacgt actggagatt aatacgcttt tattctattt tcccatcgcc
     3661 taactacatc ctttaagggt tcatccaagt aagaataggc cttatccttg atccaatcag
     3721 gaataccgta agctgcctct gctatgctac aagtgattgc tgcgagagta tcactgtcgc
     3781 caccaagtga gatggcattt cttatcgcat cttcgaagtc tctactttca agaaaggcga
     3841 taatggcttg agggacagtt tcctgacatg tttcgttaaa acgatagtta ggacggattt
     3901 catctaaagt ttgagataga ttgtaatcgt attctttttc tatataatcc ttaattcgtc
     3961 ttttacactc tgtaggattg tcgttaattg attgctcgta ctctctacaa taaccaccaa
     4021 agtaaaaacg acatagaaag atagcatcag ctgtggccat agcgcctttg acaccttctg
     4081 gatgattatg agttacctct gcagaaagac tcgtaagtcc tctagatgat ggccatatac
     4141 cagttttcgc ataaaaacca cagtccatga tccaagtaca tggagaaata cgcatagctg
     4201 atccattccc aaagctatta taaggctcac ggttatcgct gtttagccat gcattaaacc
     4261 gagcaccgta atcagcattc ggatacattc tgccatattt cttcatcgcg tcaatgaagt
     4321 cgtctttttg tccaccattc ataattgctt ctgcaacagc acaggtcata accgtgtcat
     4381 ctgtaaaaaa acagtccttc cgaaataaag gaaagtcctt tgttttgata ttgttccatt
     4441 cgtaaacaga accgacaata tctccaataa ttactccaag catcagattc ctccttgttc
     4501 attttgatgc tttttatatt ggttatctac catatttatt ttagaaaata acatcctgtt
     4561 ggattttaaa aatttcattt ttttcaaaat agggttttac catttctttc cacctagctc
     4621 tatgaaaatt gattgatttt aaaggagata ggccataatt tcccaatgca taaccatcat
     4681 ttacttcaac aacaagtgtt ctgccatcgc gagtaacacc gatatctagt ccataagcta
     4741 ttggcgcatc tttccaacat gatatcgctt catcaattac acttgcatca aattgtgcat
     4801 gataatcacc tgtatagggt cgaacatcta atacgcgacc atctaacaca aaacaacgcc
     4861 attcagctat gaattctaca acctcactaa tccatatagg atagtcgaaa ggtagaccaa
     4921 tacctattaa atcatgggtt ccattaacaa ctcttccagt aaagactttt gaaccagctt
     4981 taggcttaat aaattttccc caattatcag gtatattcac aatctctcct aaaataccag
     5041 cataaatctt tcgaccataa aactctttaa gctcaatagg atagtcatga accggaacgt
     5101 ttaagcccat catttttagt aatgctctag tctccattat ataatctaca actatatctt
     5161 cacttgttaa ctcttttatt tcagaaaaag attgatataa aataacttct tctccttgta
     5221 agtaggcacc tacttgagca ttgtatttat taattgaaac ctcacttggt aatttacttt
     5281 gtctaatata aacaaccatt tcatcactcc tatatcacta gtgttacacc aatttgtaaa
     5341 aaataatagc aattttgctc ttattttttt gagtaaatag cccccataat atcatcgaaa
     5401 taatcaacgg tatttaggag taattcaata acctgggact ttgttagtcg cattcccctt
     5461 ctatctctag catcttctac taaattttca agtttctcta gatttttatc atccaagcta
     5521 atcattattc tatttttatc ggttgccatt ttcatcacct caagttaatt ctatcacagg
     5581 tgtaacactt gtgtcaactg gcttttataa tacattagtt taaaagtgga gaggattttt
     5641 aacacagtaa ctttaaatct ttggtattaa aaaattttca caatatttat agaaataaaa
     5701 tctgtctcaa atcagttatc aaatctagta taaattatga gcggctactc taatactttc
     5761 cctctaaaca agaaaaaaac ttacactcaa gggttttctt cccccccttc gttataacgt
     5821 tttgactctt ttactagcaa aggtatatac tcacaaggaa ctttggttga ctattgaatc
     5881 tctccaactt cttctttaac atatccttct acatcttcaa tctctacaaa cattgggtct
     5941 aagtgacaca agaaatgcca aacttcgatc cctttttttc tgtaaagaat cgcttcaccg
     6001 tcttcacttc cgaaaaagct tctgtcgatt tcatatccgc ggctttctaa gaagtctttt
     6061 gctttacgat agttcgtttc tcttgtttcg acataggctt taacttcatg gttgttaacg
     6121 acatatgcat caatttttga atatccttcg atcactctat catttttgag ggataaattt
     6181 gaaatctctt tccaaataat gtttacattt tcctcaggat cgaacataaa tttagataaa
     6241 ggaacaatat ttccgttaaa aataatttcc atataatccg gtatgttttt aggattaaaa
     6301 tactccactt caaaaccatc ttctgtttcc agagtgtatc ccgggatttg agccacaaag
     6361 gctttcccat cttctatgga atcaaatgct actaaatctt tagaataatc attttggtac
     6421 aattccaata taaccatcga taatctctcc attttcatta tcaggctaat gtaaataagc
     6481 acgtcacctg accaattcag gctctctgta tcatctcatc atatttccta cttactttac
     6541 gagtcctata cccagaacac accttatcga ccttcggtct cacctcgtcg cattggctga
     6601 acatctactt ttacttcgct gatgcttcaa ctcgtacaag cagtgatacc gcctcagcgt
     6661 gatgcgtcag tgggactcaa aaagtttggg gaaccttttg aggattaact acgtttctct
     6721 aataaactta cacattcaac ttgttcatca ttgtccaaat ctatgttgag attttcttct
     6781 ataattggta gcttaaaagt aatggatttt agccattgtc cgttagattg tttttcttca
     6841 taaacttgaa tttcagaaat caaagctgaa attaactgcc tacgctctac atcattcatg
     6901 actttataga gcttatcaaa atagatcaga accttatata tgttatctcc tgtaagtttt
     6961 tcagcttcaa tagtctgttt ctttgctttc gcatcaatta gtgatgattc taattcatct
     7021 attttgtcat acatacgata tagtctatca tctaaatcct gtttccttct cttatagtgc
     7081 ttatcttcaa catctaaatt atctatttcc tcaattagct taaactttgt agaatgactc
     7141 tttctcaatt ccttttggta attatctatt tctttttcta tttcagaggt atccaccttc
     7201 atgttgattt tttcttgcat catagaagca aatttcggat tacttactat cttgacaatc
     7261 acctctgcaa cagcatcatc taacaattct tctctaattt gcttactgaa tgtacactta
     7321 tgacctctta tcatctgcct atgtttacaa ccatagtaat aaaaatcttt atactttgtg
     7381 ccatctttct ttttcttgat acacttgttc ccaaacattc ccactccaca tatcgggcat
     7441 tttacaattc cagaaagcaa gtgtgtgcgt gtatcttttc ctttattcac atgctcatat
     7501 ttctttgctt gagattttag cttaacctga gcagcttgcc aaacttcatc ggaaactata
     7561 gcttcatgta tcccttcaga tattagatat tcatcttgtt caacctgctt atattcattt
     7621 cttgtaccat gaactttttc taaagttctt cttccaaatg ctattttccc attatataca
     7681 ggattcttta atatctttct tataagacct gcatcaaaca aaggattctt accattctgt
     7741 cttgggattt ttctaattcc atgattctct aagtatttag atatcccatt ggctcctatc
     7801 gtagtattta catactggtc gaaaatcgtt cttattgcaa ctgcctcttc ctcatttata
     7861 aacagcttgc cgtcttcaag tttatatcca tacggagcaa agccaccatt ccattttcct
     7921 tcccttgctt tttgaatgca accttccatt gtttgaatac ggatgttttc tctttctatt
     7981 tcagccacag ctgataaaac agaaatcatt agtttcccag catctttaga tgaatcaatg
     8041 ccatcttcaa cgcagataag attaactcca taatcctgca ttatctgaag tgtagaaaga
     8101 acatcagcgg catttcttgc aaatcttgat aacttaaaca caagaacaaa agatactcca
     8161 tcttttccag attttatatc ttccatcatt cgattgaact gtattctacc ttcaatagac
     8221 ttgccagact tcccggcatc ttcatactct ccaacaattt cataatcgtt gtaaatagca
     8281 aaagctttca ttcgtgattt ttgtgcctct aacgaatacc cctctatctg tattgacgta
     8341 gatactcgtg tatagaggta tacttttatt ttttcttttg acatagtatt aacctcaata
     8401 taatttttct atatcatata taattttttt aatttaagtt tggactatca tttcaagtat
     8461 attataacac ttttattagt ccgtctcaat ttgtgttttt gccatgtcaa aactattttt
     8521 catctcttga ttttttgctg gcgttggatc gggtagatta tctaaatcta aagcaccagc
     8581 atattttgca atcagatttg ctattaaatc agccaatcca ttccagtcat tgtccaatat
     8641 atacctcctc taaagtttta tatctaataa ttatttgttt aattaagttt tttgacattg
     8701 acaagtgctt tggattagca acataggaat ctcacctccg cctctattcc ggatgagccg
     8761 gcttcaacct tagaagtatc attatcctca ttttcttcat agcggatagg gtatccctcc
     8821 ctatattcaa actcttactt atcgctcact ttctttttgc ttagcagaac tttttttgcc
     8881 gaattattca gccgaaagat cttgacggat aggttattac gctccaaaaa taattaacgt
     8941 cttgtcttgg tctattcaat tgttaaggtt caaaatttat cgagagttat taatcttttt
     9001 aaaatttgac catcagaaaa tatttatctt gatgtaacaa aattctataa attaccctct
     9061 tatacttaac agtgaaaaga agtctttctt ggtaaccaat tttgaaatag aatttgctta
     9121 tataaaaagg tccaattccc actgcataag tagcagtgaa aattagaccc tcttggtaac
     9181 tgtcatctaa aagtcttcta gcatttcttt aattttctaa tcgcctttaa agtgtcatat
     9241 ttatattttt ttatctctgg catactttga taccttttta gacttaaagt ctttaatagt
     9301 gcctttccac ctctttttat ctataaagat tctcctacat cataattcat ttttttattt
     9361 aaacctttct gtcttagttt gtctttatct tcttcatacc attttaagat tgtcacatag
     9421 tggttttgat aggtcttacc actgctttcc atgtatctgg atagtttatt tatcattata
     9481 tctgtgtgtg agtttaattt ttcttttaga tttttatatt cttctttgct taaccttaca
     9541 tttttgaatt ctccataaaa aatgggggtg gactttttat ctatctctcc ctctctctct
     9601 ttatctatct ctatatcttt ccatgtaatt ccaatctgga gtacctctac tgtctatcgg
     9661 taatttaatt ttgatatctg gcaatactgt gctagatatt tgatctttat attcagtatt
     9721 ttttaaagct tgcctaataa ttgaagttaa atagaatgct acttctttat tcaattcttt
     9781 attttttaat ttt
//
LOCUS       DAVLZS010000062         9445 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLZS010000062 DAVLZS010000000
VERSION     DAVLZS010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.062"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            59..637
                     /locus_tag="VYO88_001786"
                     /pseudo
     CDS             59..637
                     /locus_tag="VYO88_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(926..1396)
                     /locus_tag="VYO88_001787"
     CDS             complement(926..1396)
                     /locus_tag="VYO88_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV1719836.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(1362..2168)
                     /locus_tag="VYO88_001788"
     CDS             complement(1362..2168)
                     /locus_tag="VYO88_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1719837.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(2374..3015)
                     /locus_tag="VYO88_001789"
     CDS             complement(2374..3015)
                     /locus_tag="VYO88_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719838.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(3012..5120)
                     /locus_tag="VYO88_001790"
     CDS             complement(3012..5120)
                     /locus_tag="VYO88_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1719839.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(5175..5468)
                     /locus_tag="VYO88_001791"
     CDS             complement(5175..5468)
                     /locus_tag="VYO88_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1719840.1"
                     /translation="MIGEINHEKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSG
                     NFGYSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            5875..6195
                     /locus_tag="VYO88_001792"
     CDS             5875..6195
                     /locus_tag="VYO88_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1719841.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICTDDSKLIQKGVSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(6247..6834)
                     /locus_tag="VYO88_001793"
     CDS             complement(6247..6834)
                     /locus_tag="VYO88_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1719842.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            7076..7747
                     /gene="sdaAB"
                     /locus_tag="VYO88_001794"
     CDS             7076..7747
                     /gene="sdaAB"
                     /locus_tag="VYO88_001794"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1719843.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNVHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            7756..8628
                     /gene="sdaAA"
                     /locus_tag="VYO88_001795"
     CDS             7756..8628
                     /gene="sdaAA"
                     /locus_tag="VYO88_001795"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1719844.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            8650..9282
                     /locus_tag="VYO88_001796"
     CDS             8650..9282
                     /locus_tag="VYO88_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1719845.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
BASE COUNT         2871 a         2086 c         1646 g         2842 t
ORIGIN      
        1 gctttcaaat ttctaggctc aggctgaaac agtctcccag actgtttcac tcccgaatgc
       61 taaaatcgtt cttgatcgct ttcacattgt gcaacatctt agccgtgcta tgagtcgtgt
      121 gcgtgttcaa atcatgaatc agtttcatcg aaaatcccat gaatacaagg ctatcaagcg
      181 ttactggaaa ctcatccaac aggatagtcg taaactcagc gataaacgtt tttatcgccc
      241 tacttttcgc atgcacttaa caaataaaga aattcttgac aagattttaa gctattcaga
      301 agacttgaaa caccactatc agatctatca actcttactt tttcactttc agaacaaaga
      361 ccctgagaaa tttttcggac tcattgagga caatctgaag caggttcatc ctatttttca
      421 gactgtcttt aaaaccttcc tcaaagataa agaaaagatt atcaacgccc ttcaactaca
      481 ctattctaat gccaaactgg aagcgaccaa taatctcatc aaacttatca agcgcaatgc
      541 ctttggtttt cgaaactttg aaaacttcaa aaaacggatt gttatcgctt tgaacatcaa
      601 aaaagaaagg acgaaatttg tcctttctcg agcttagctg acttcaaccc actacagttg
      661 acaaagagcc ttatttgttc gttagttctt aataccagcc attgttaaac cagaagtttt
      721 tagctctgcc aagccacata gtgtgtttac tactatgtgt ccatgtcacc atgaatcgcc
      781 gaacgattta acgagaaagt atgactttta cgtttatccc aactcaatta tgacattttt
      841 ttcaaaagtc aatatatctc actttttcaa cgacaagaaa gaggctacca atcgaccaac
      901 ctcttattct gaacccatca ctccatcact ttttagcttc attcgctttc ttagcgactg
      961 caatctggta ttcgacttgg tcattcccct taccggtaca accatgagca attgtagtcg
     1021 ctcctatctg atgcgctatt tcaaccaatt ttttagaaat cagagggcgg ctcaaggcag
     1081 ataccaaggg atacttttgt tcataatagg catgtgactg atgagccact agcacataat
     1141 ctgtagcaaa ttcgtcctta acatcaatga cataagattc tactgcccca accttaagag
     1201 ccttatcatg gatgaaatct aagtctttcc cttcacccac atccatacaa actgaaacaa
     1261 catcatagtc tttctttaac caggtaatag caactgatgt gtccaaaccg ccagaatagg
     1321 ccaaaattac tttttcttta ctcatgttct tttccttctt tctatttttc aatggatgct
     1381 ttaaaggcat cctcaatgag tttgtctaat tccccagact ccttcaactt ttgaatggtt
     1441 ttatcgactg cctctttcaa ttccttgcta tcttttttca tggctaccgc ataggaatca
     1501 tcttgctctt tttcaaaatt gaggtctgcg attgctaaat caggattatt ttccacaaat
     1561 cccttggcaa cgggttcttc aaaaataacg gcatccactt gccctgattt taaatctgtg
     1621 attaaattcc catttttagg cagagatacg agggaagaat tttgtagcaa atctttcgcc
     1681 atcgtctctt gaatcgaacc tttctgcgct ccgacctttt tctgcgccaa atcgttgaca
     1741 gactgataag tggctaaatc agattttttg acaatgagtt tattttttgc agtatagtag
     1801 ggagttgaaa aatcaaacac cttgctccgt tcatctgtct tagaaacacc tgatatggca
     1861 aggtcagctt ttcctgattg aacgctagcc agtacattgt caaaactcat aggagatagt
     1921 tccaattcga cacctagttc tgttgcgata gccttggcta attcgatatc tgaacccaca
     1981 atctgatttt tcccatcaac cactttttga tattcaaatg gagcaaaatc tggattgagg
     2041 gctacaacca attttccttt ggacttgatg gcttcaattc cagccgattg attgttacta
     2101 caagcaaata gtagggggag catcactaaa ccaaacatcg tcatcaacac cttcttcatc
     2161 ttattcataa caaagcctcc tttatgttta ttctttttta ttgtataaat aatactccta
     2221 tactcatcct ttgtcaagcc taaattgtaa ttttttcaat ttgaaacaaa aaaaacctag
     2281 aaatactaca taaaatgtca ttcctaggcg tatttatgct atttttctct agaaaacatg
     2341 agtattcagc cagtcaaaag gagctgaatg aactcatttt ccctcgccca attcaatgac
     2401 acgatgacat tgttgggcta cataagcatc gtgggtcaca ataatgactg ttttcccttc
     2461 tcgattcatc tctaagagaa acttcaagac caaatctcta ttttcaggat ccagcgaacc
     2521 tgtaggttca tcggctaaaa tcagctggct gggttttaag atggctctag caactgcaat
     2581 tcgttgttgt tcgcccccag acaactcgga gaccctttga tgcaaagtag ctgacaaacc
     2641 tactctctct aaaatctctt ccaccttttt gagcttgtct ttcttaggca atttcacata
     2701 tttcagcgcc agcatgagat tgtactcgac cgtttcatca tcaatcaggg caaaattttg
     2761 aaacagataa gagatatgtt cacggattat tgtttgcgac ttagcagaat taaccgctag
     2821 atttgtctga ccaaaaatct cataccgtcc gctataatca ccatctatca aacccaataa
     2881 atttaacaag gtcgacttcc cactaccact cttaccaaca atagctacca aatccccctg
     2941 atcaatcctg agagataagt tatccaaaat cacttttccc ccaatggttt tggtaatatt
     3001 tttcaactca atcataagat gccccctttc aataactcta ctagacttct tttctccatc
     3061 ctagaagcta agcctagcac aaatagtata tccagacatg taaaacctgc aaacagtaga
     3121 agtggtaaga acgcatgggc aaagaaaatc aagactagaa gagggaaact atagcccagc
     3181 aagagcagaa cgaggagagg acggtagcga tcgaccagtt tccaccccat aaacttcttg
     3241 gtaatgatat ccctgcgctt caataagaaa gttgttacta gtaagaagta ggaaatcatc
     3301 atgctaagga gaccaaacaa agcaaagagt aggttaaaat tccgaacagc atctcgataa
     3361 gaatccactt tctcttgttg aatggcttga atagatgaaa attttaaata atttccatct
     3421 gacaatttct caactaactc tgtaatctct ttttgatgtt gaaccgtatt ttcaatttta
     3481 atcggattat ttaagccagt tgttgacagg gaggctttct catcccacat catatcagaa
     3541 tcattgacca agctaataat tggattggag agattttcct ttcgcttatc actatatggg
     3601 aaaaatgacc aatctccttc ataataggca atctcgacat ccatctcctc tatcgttcgt
     3661 ttttgctgct cttcatactt catcgaatga aaggcaatta acttccccaa gagctgattt
     3721 ttatcttctt cacctttcgt acttgctggc atcaaaataa cttttttaat accggtatct
     3781 ggtagcttga atcccttgct ctttagaaaa ttgcgattgg catagtaaac atccaccgta
     3841 tctgttaact gatattgctg aatctgttct gattggacaa aattttttac aggaagactg
     3901 ctactctgca catagcccgc ctgcgttttt tctaccaaat cctgataaaa tcgatagaaa
     3961 taatctgtag atttccctga ccctgctagc tcttcttgcc acagattatc attgagtttg
     4021 aaggtttcta aggtcaggta attaccttga cttacccact gttgctgata agcaagttct
     4081 ttgttttctt gttctaaact tctgcccacc ccaatcagta aggccgtcag taaaatagtt
     4141 gtccctattt tcatcacata attgaagata agaccaaatt tgaaagatga aaaacctttc
     4201 agcagagagc tgattgtcat tttttggatt aagaggtaag tcaaccaact gataaagaga
     4261 taaagctgca acagcaaaaa atgagacaac cacagcatag gaaacaaatc ttttggctta
     4321 taatcaagca agaaaaacac gcctagattg atcacaagag ccccacctag gaggaggtaa
     4381 aggttgcctt ttacaacatc agctaaaaca gccctatctt gaaaaccaag taatttttgt
     4441 accccaactc ttttcatctc catcatcggt tgatacactg tcactaacac aagaagcaaa
     4501 atagccaaga caaaaacaat ggcagataaa agcaaatctc gatttatgac ttccactgca
     4561 cttttgtagg tcggctctag caaggtagcc tggtctatct tgaaaaaatc gctccatttc
     4621 tgtacaatcc tatccttgtc catctcttgt gtagaagtta tcgtatagcg accatttaaa
     4681 ctacgagatg tatccttgat ataggtttga aaagtcataa gctgaatagg tttggctttt
     4741 agaaaggtcg gaatcgtacc aagtttattg gaaatttctt tattactata gactccttca
     4801 ccatctgtgg taaaatcaag agaagaaatc ccaaactctt ggtaggggaa ggtatcttta
     4861 tcaaaaacac cagacttgac cacctcatca ccactgtctg ttttgatgat ggagacttta
     4921 tactcctttg atacatcctc aaaaaatcga agaacagacg ctgcaggttc gttaatatct
     4981 ttcaaataca aatccaaaga atctacagtc tttcccattt cttgaatccg aaccacttct
     5041 cgtgtatagt ttacattaaa aacaaaaaaa gtggtacaca gaagcaggag taacatacaa
     5101 agatgactga tttttttcat agagatacct cccgtgaaga aactccctct ccaaaagggg
     5161 agggagaatt ttaattaaaa tccatagaaa tattccattc ccgttggtgg gaatttgaag
     5221 attgaagccc gagcccatgc ctcagcttct gcacgatcct tagagaattt atttccatct
     5281 ttaacagttg ctgtatgaga gcgagtagaa tgtaaataat cagaataacc aaaatttcct
     5341 gaccatccta ctccatagtt ccattgacca ccatcaaccc atactgccaa aacacttgta
     5401 gaagcaagta tactacatac cattaaagat gcaacaccaa ttttctcatg atttatttct
     5461 cctattatcg agagctattc cgtagaaaca gctatagtaa tttgtcaaca agtatcgtag
     5521 tccattggac tcaccttcct tctatctcat ttcattttta aacaacgaac ttactcttaa
     5581 ctagaagaat agttctcttc tgtatcaggt cttttaacaa ccagagtagt attaatcaca
     5641 ctctaactat tactcaagaa tcagcccaat aaacaatatg gatagcgctt tcaaattttt
     5701 aaactcttat cccatccttt tatctatata ataagtgaaa atataataac tgtcaagtaa
     5761 tcgaagtgaa ttttataaaa aaaattacaa gccaaatttg caaagtttac aataagccgc
     5821 tagggcaatc gtctatcaga atgtccgttt atttgtcaat aatccgagaa aatcttgcaa
     5881 cgcttagaag tctataaaaa ctatcaacat ttatatgact tgcgaatagc aatcctgctc
     5941 aacctttcca cactctatct atacaatcaa gataaaaaca tgtgtaagca aatctgctac
     6001 actttactag aggacgccaa gaataagaaa agctacgata ggctggctat ctgctatgtc
     6061 cctattggga tttgtacaga cgattctaaa cttatccaaa aaggggtctc ccttctggag
     6121 ctaaccgagg aaacttctat gctgtctcat ctcaaaaaag aagtagagat ctattaccaa
     6181 gcgaaggaaa gataaaaaag ccgagggatt tcctcgactc tttacatatt atttgttcgt
     6241 tagttcttaa taccagccat tgttaagcca gaagttttta gcagcagtcc atgaaccgta
     6301 acgtcctgca acgtaggcat ctgctacacg ttcttggttt tcagctgagt agtcaccgtt
     6361 caggtatgaa tctgttaatt ggtaacgtcc gatataacgt ccatttgtag ctgtatagct
     6421 accacctgat tctttttgag cgatccattc tttggcttct gcttcagatc cgcttacagt
     6481 tgaaacaact gtttcactta ctactggagt ttctgctact ggagctgaaa cagtttcatc
     6541 ttgagcggct ggtgccgcat aagtagctgg cgctggtgtt gcaacaggcg ctacagggcc
     6601 atcgataacc aactcttgac caacataaat caaatgaatg ttatcaatgt ggttgttttc
     6661 tgccaatttt tcaactgttg tgttgtgagt ttcagcgatt tctgaaagtg tatcaccttc
     6721 tttaacagtg taagttgatg attcttgagc agatacaaat gatggagcaa atactgcaaa
     6781 caaggcagct actcctgcaa gagttgcttt aatcttttta gttattgatt tcatattcga
     6841 aaattctcct tctttctata gttctatcat accctttaaa tattaccgtt tcttgacact
     6901 tttatgtaga aatattacaa aattattttt tatttcccta aataaggtgt tttttgtcat
     6961 aaaagatact atttttatgc tatttgaggt attagaaagg ttttcatcca caattaaagc
     7021 caagcccctc attctttgat ataatagaga taagaatttt tataagggga aactgatgaa
     7081 atcacttcgt tttcaatctg tctttgatat catcggacca gttatgattg gcccatctag
     7141 tagccatacc gctggtgctg ttcgtattgg gaagattgtc tcttccattt ttgatgatac
     7201 tccgacagaa gttgaattcc aactttttaa ctcatttgcc aagacctatc gtggtcacgg
     7261 aacagaccta gcccttgttg caggtatttt aggcatggat acagatgatc ctgaaattcc
     7321 aaacagtctg gagattgccc acaagcgtgg tatcaagatt gtctggacca ttcagaaaga
     7381 cagcaatgcc cctcacccca acaccactaa aattaccgtc aaaaatgtac acaagaccat
     7441 cagcgtgact ggtatttcta tcggtggagg aaatattcag gtaaccgaac tcaatggttt
     7501 tgccgtctct ctcaatatga atacaccgac tatcatcatc gttcatcaag atattccagg
     7561 tatgattgcc cttgttacag aggcgctttc ccgctatggt atcaatatcg cccagatgaa
     7621 tgtcactcgt gaaaaagctg gtgaaaaagc cattatgatt atcgaagttg acagtcgcaa
     7681 ctgcgatgag gctatcgaag aaattcgaaa aatccctcat ctccacaatg tcaatttctt
     7741 taaataggag gaagcatgtt ttattctatc aaagaattgg tcgagcaagc agatctggac
     7801 tttcaaggaa atgtcgcaga actcatgatt acaacagagt ttgaattgac cggtcgcgaa
     7861 cgtgaagaag tcttccttct catggaacgc aatctggaag ttatgaaagc ctctgtccaa
     7921 cttggcctca atgaaaataa atctcgtagt ggcctgacag gtggagatgc tgccaaattg
     7981 gatcactaca tcgaaaacgg aaaaactctg tcagattata cgattctctc ggctgcccga
     8041 aatgccatcg cagtcaatga acacaatgcc aaaatgggct tggtctgtgc cactccaacc
     8101 gctggaagtg ctggctgtct gccatccgtt ctcactgctg ctattgaaaa attagacctc
     8161 agccacgagc aacaattgga tttcctcttt gctgctggtg cctttggact agtcatcgca
     8221 aacaatgcct ccatctcagg tgctgagggt gggtgtcaag ctgaagttgg ttcagcctct
     8281 gctatgagtg ctgccgcctt gactctggct gcaggtggaa caccttatca ggccagtcaa
     8341 gctattgcct ttgtcattaa aaatatgcta ggcctcatct gtgaccctgt tgcaggtttg
     8401 gtcgaagttc cctgtgtcaa acgtaatgcc atgggagcta gctttgcttt catcgcagca
     8461 gacatggcct tggcaggtat cgaatctaaa atccctgtgg atgaagtgat cgatgccatg
     8521 taccaagtag gagcaagcat gccaactgcc tttcgtgaaa cagctgaagg tggactcgct
     8581 accaccccta ctggtcgtcg cctccaaaaa gagattttcg gagaataagc ttatcaaata
     8641 ggagaaacca tgacctctat cacagcgatt tttttcgatt tggatggaac cctcgttgat
     8701 agttctatcg ggattcacaa tgcctttacc tataccttta aagagctggg ggtgcctagc
     8761 cctgatgcca aaactattcg tggttttatg ggaccacctc tcgaaagtag ttttgcgacc
     8821 tgcctgtcca aagaccaaat ttctgaagcc atgcagatat atcgttctta ctataaggca
     8881 aaaggcatct atgaagctca actctttcct cagattatag acttgcttga ggagttatcg
     8941 agcagttatc cactctacat caccacgaca aagaatacat ctactgctca agacatggcc
     9001 aaaaacttgg aaatccatca tttctttgat ggtatttatg gttctagccc tgaagcaccc
     9061 cataaggcag atgtcattca ccaagcctta cagacacatc aactagcacc agaacaagcc
     9121 atcatcatcg gagataccaa gtttgatatg ctgggagctc gagaaacagg tattcagaaa
     9181 ttggccgtca cttggggatt tggagagcaa gcagatctac taaactatca acctgattat
     9241 atcgctcaca aacccttaga agttttggcg tattttcaat agcatagact gggtaacaac
     9301 tccatttcag aagaaaatga agtaatactc aatgaaaatc aaagagcaaa ctaggaaact
     9361 agctgcgggc tgctcaaaac actgttttga ggttgcagat agaactgacg aagtcagctc
     9421 aaaacactgt tttaaggttg tggat
//
LOCUS       DAVLZS010000063         9429 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLZS010000063 DAVLZS010000000
VERSION     DAVLZS010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9429
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.063"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            70..1329
                     /locus_tag="VYO88_001797"
     CDS             70..1329
                     /locus_tag="VYO88_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1719846.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1405..1540
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1579..2079
                     /locus_tag="VYO88_001798"
     CDS             1579..2079
                     /locus_tag="VYO88_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1719847.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2155..2523
                     /gene="rplL"
                     /locus_tag="VYO88_001799"
     CDS             2155..2523
                     /gene="rplL"
                     /locus_tag="VYO88_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1719848.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2722..2895
                     /locus_tag="VYO88_001800"
     CDS             2722..2895
                     /locus_tag="VYO88_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719849.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQS"
     gene            2892..3140
                     /locus_tag="VYO88_001801"
                     /pseudo
     CDS             2892..3140
                     /locus_tag="VYO88_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3154..3477
                     /locus_tag="VYO88_001802"
     CDS             3154..3477
                     /locus_tag="VYO88_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719850.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGADAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKQPINFANLLDSLIVSEYQMEPNIW
                     EVSHD"
     gene            3470..3850
                     /locus_tag="VYO88_001803"
     CDS             3470..3850
                     /locus_tag="VYO88_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1719851.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTRDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLVVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLYN"
     gene            3863..4006
                     /locus_tag="VYO88_001804"
     CDS             3863..4006
                     /locus_tag="VYO88_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719852.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4099..4686
                     /locus_tag="VYO88_001805"
     CDS             4099..4686
                     /locus_tag="VYO88_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1719853.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRNLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            4888..5025
                     /locus_tag="VYO88_001806"
                     /pseudo
     CDS             4888..5025
                     /locus_tag="VYO88_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
     gene            5315..6718
                     /locus_tag="VYO88_001807"
     CDS             5315..6718
                     /locus_tag="VYO88_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV1719854.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            6907..7525
                     /locus_tag="VYO88_001808"
                     /pseudo
     CDS             6907..7525
                     /locus_tag="VYO88_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            7540..8280
                     /locus_tag="VYO88_001809"
     CDS             7540..8280
                     /locus_tag="VYO88_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719855.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            8283..>9429
                     /locus_tag="VYO88_001810"
     CDS             8283..>9429
                     /locus_tag="VYO88_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719856.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQMSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLTGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERTEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLL"
BASE COUNT         3125 a         1403 c         1895 g         3006 t
ORIGIN      
        1 acctacggca aagtgaatct gaagtggttt gaagagagta caacttgtct tttagaaaag
       61 gagcctataa tgaaagtctt tcagcatgta aatatcgtga cttgtgatca agatttccat
      121 gtttatcttg atggaatctt agcagtcaag gattctcaaa tcgtctatgt cggtcaagat
      181 aagccagcgt ttttagagca agctgagcag attatagact atcagggagc ttggattatg
      241 cctggtttgg tcaattgtca cacccattct gcaatgacag gtctgagagg gatccgagat
      301 gacagcaatc tccatgaatg gctcaatgac tatatctggc cagcagaatc tgagtttact
      361 cccgacatga ctaccaatgc ggtcaaagaa gccctgacag agatgctcca gtcaggaaca
      421 acaaccttta acgatatgta taatcccaat ggtgtggata ttcagcaaat ttatcaggtg
      481 gtgaaaactt ccaagatgcg ttgttatttt tctccgactc tcttttcttc agagacagaa
      541 acaactgctg agactataag cagaactcga tccatcatag acgaaatctt aaaatataaa
      601 aatccaaatt tcaaggttat ggtagcacct cattctccgt atagctgcag tagagacttg
      661 ctggaagcga gtttggaaat ggcaaaagag ctaaatattc cgctccatgt ccatgtggcg
      721 gagaccaagg aggagtcagg aattatcctc aaacgatacg gcaaacgccc ccttgctttt
      781 cttgaagaac tgggttattt agatcatccg tccgtatttg ctcacggggt cgaattaaac
      841 gagagagaaa ttgaacgctt ggcatcttct caagtggcta tcgcccacaa tcctatcagt
      901 aacctcaaac tggcatcagg aattgctcca attatccagc tccaaaaagc gggagtagca
      961 gtcggaattg cgactgactc ggttgcttcc aataacaatc tagatatgtt tgaggaagga
     1021 aggactgcag ctcttcttca gaagatgaaa agtggggatg ccagccagtt tccaatcgaa
     1081 acagctctca aggtactgac aatcgaaggg gctaaggccc ttggaatgga aaatcagata
     1141 ggaagtctgg aagtcggcaa gcaagcagat tttctggtca ttcaaccaca agggaaaatt
     1201 catctccaac ctcaggaaaa tatgctgtct cacctggttt atgcagttaa atctagtgat
     1261 gtagatgatg tttatatcgc cggagaacag gttgttaagc aaggtcaagt cctgacagta
     1321 gaactttaaa agaaaaatca cgaaaaattt taaaaaaagt ttgcaaaaat cttgcattct
     1381 ttttttgact atgctatact tatatacggt ttaaaaaaac tgcctaagac agtaggggag
     1441 ctcgactcat aaatatccta ccgaggacaa gacgtatcat gtaaaaagaa gcgtattgta
     1501 ctttcgtgtc taggtttggg cgcgtttttc tttttgaaaa attccccaag caaaataatt
     1561 acggaggtga acacactaat gagtgaagca attattgcta aaaaagcgga actagttgac
     1621 gtagtagctg aaaaaatgaa agctgctgca tctatcgtcg ttgtagacgc tcgtggtttg
     1681 acagttgagc aagatacagt tcttcgtcgc gagcttcgtg gaagcgaagt tgagtataaa
     1741 gttattaaaa actcaatctt gcgtcgtgca gctgaaaaag ctggtcttga agatcttgca
     1801 tctgtatttg ttggaccatc tgcagtagca ttttctaatg aagatgttat cgcaccagcg
     1861 aaaatcttga acgacttttc taaaaacgct gaagcacttg aaattaaagg tggtgcaatc
     1921 gaaggcgctg tcgcatctaa agaagagatt cttgcacttg caactcttcc aaaccgcgaa
     1981 ggacttcttt ctatgctcct ttctgtactt caagcgccag tgcgcaacgt tgctcttgca
     2041 gtcaaagcgg ttgcagaaag caaagaagac gcggcttaat cttaagctac acagcgtagc
     2101 ctagctacga aaaaaactat tataaaattt aaaacttatt tggaggaaat aacaatggca
     2161 ttgaacattg aaaacattat tgctgaaatt aaagaagctt caatccttga attgaacgac
     2221 cttgtaaaag ctatcgaaga agaatttggt gtaactgcag ctgctcctgt agctgttgct
     2281 gcagctgatg cagctgatgc tggtgctgct aaagattcat tcgacgttga attgacatct
     2341 gcaggcgaca aaaaagttgg tgttatcaaa gttgtacgtg aaatcactgg tcttggtctt
     2401 aaagaagcta aagaacttgt tgacggtgca ccagcacttg ttaaagaagg cgttgcaact
     2461 gcagaagctg aagaaatcaa agctaaattg gaagaagctg gagcttcagt tactcttaaa
     2521 taagaggcat ataccaatta gaattcggaa tactatagta tcagcctttt agaatcgtga
     2581 acacatttta gaaactgata aatttattta gtttcctacc aaaaacccta ccaaaaattc
     2641 tttggcaggg tttttgtttt aataaacttt cgggggtaga cactagattg tctacccttt
     2701 ttttgtgttt cggaggtaat tatgcaaaag gaaggacagt catcacgtca attcgtgaag
     2761 agtcatctca tgactatcat gggagttgat attgtaaaag caactcagtt agttgatgaa
     2821 atggaacaag taggtttaat ccgatttgat gaatttggaa atgttggaat tttagtcttg
     2881 gagggacaat catgaagcgt attaccgcta gtcaatatca gacatcagag cgttattata
     2941 agctccccaa acttttattt gagagtgaac ggtataagaa tatgaaactg gaggttaagg
     3001 tggtttactc agttttaaaa gatcggttgg agttgtcttt gagcaaaggt tggattgatg
     3061 aggatggggc tatttatttg atttattcca attcaaattt gatggcactt ttaggctgtt
     3121 caaagtcaaa attactctcc atgtgagttt gaagtgacat ttttagatga ttaccataaa
     3181 aaacacaact accccctatt ttacgaatcc taccttcaaa acgttatgga attccttgaa
     3241 agtcaggata taaagaacgg agctgatgcc tttgtagatg atcatcaaaa tcttgttttt
     3301 gttttatatg gacaaggcta tcgagccgag ggaaaagagg gaatacttac aacccaagta
     3361 actgtaaaag cttatgatga agacaagcaa ccgattaact tcgcaaattt attagattcc
     3421 ttaatcgtat cagaatatca aatggaaccg aatatttggg aggtctccca tgattgatct
     3481 ctatctaagt aaaaatagcc aaagaaatca acttctttta gactttttcc aaaactatgg
     3541 tatcgaggta tcttgtcatt cagtttctga aatgacaagg gataaattaa ttgagatgat
     3601 gagttattct tcagattgtt ttgagttttt atctcccaat ttattgcgat ttaagaaccg
     3661 tgacaatcta agattaacgg atttcgttga gataatttta aaaaatcctg aactaaccat
     3721 cagacttcct cttgtggttt caaataagcg ggtttatcca agtctgaatt tggaagaggc
     3781 tagagctcta ttgccaagag atacgaaaca attgatttac atggcacaaa cacattattt
     3841 atataactaa aggagaagca atatggctga acgattttgg gagaacttgt ccattatttt
     3901 ggctgaaaga aatatcagct ggattgagtt aaccagaaaa atgtttgcgg gagagtttca
     3961 ctatccaagt gaattgaatc gtttgtatca aaagattcgc cactagaaga tggaacaatg
     4021 aatgcctcaa agtccatggg tagaaaggat tgtgcaggta ttagatttag attatgaaga
     4081 tttatttcgg aggtaactat gaaaagaata attccagttt atatattcca acaagtaaat
     4141 gtcctattgg tatctctata cttattgaaa tttctttgta tcggtgagtt aactatacta
     4201 cagattctct atggttcgtc actcatttct tttttatgga tgtatggcca acgcaaacaa
     4261 gcgcataagg tcaatatgaa atctaggatg aaatggcttg gtgttgaatt tgttagccta
     4321 ctgattataa gtctatgttt tagtctgatt catgctcaag gaagcacgaa tcaagcaaac
     4381 ttaattggcc ttcaacatca aattccttgg ttttcatttt tattgttctt aatcaatgcg
     4441 agtatggttg aagaatttct gtatcgagaa attttatgga atttggtcag aaatttagat
     4501 attcgagttg ctttgacaag tgttttattt gccttagcac atcatacagg aaccattcta
     4561 gcttggtgtt tgtatgtttc acttgggatg tttttaggta tggtgcgcta taaatctgac
     4621 ttatggggca gtatgggact acatttggtg tggaacctac tagtttatag tttgctgctt
     4681 ttttaaaata ggtaacctga tttttaggta acttctaaaa ctaacttcca gttttgggag
     4741 agagatggaa gttactttga aaagttacgg aaacattatt ttctatgtga caacattgta
     4801 tcattgcttg cattttactg ctggagagag tataatgaag gtggataaag cacttaatcc
     4861 taaaaattta aataggagga gttagctatg gcagaagaag tattaaatct ttaattagta
     4921 tctgttcaag ttgacgaaac agatgaagtt gatggaatgc gatttagtac attcagtaca
     4981 aaccgttgcg gtaactggag tgcttttagt tgggaaaatt gttaattcat ttaaattgta
     5041 aactttagag attctctgga gttatggatc tcgttccaat atgtgcacgt tggaatgtca
     5101 gtgcttatat ggggggaatc caaaggattc tcccttttta ttttaataag tctgtctagc
     5161 tatagatata ttaagtttga tagaatttct tggagatttt gttatggatt ataatttcaa
     5221 tttggagcat cctttctttt tcactaataa tgattatagt acagatacta gcataaagta
     5281 ctaagtaagt ctgcctttta attggcacga agtaatgaat aatgatgagt gggtttatca
     5341 ataccctatt ggaaaatttg ttgaaagaca agggtggaaa atacacatta gttcagagta
     5401 taatagttca cacgagttgt tacaagatgt agcaaaaatt tgccatgaaa tgcgaattcc
     5461 atttaaacat cttagtacag aagacaaatt tatcatgcga aacgggaaat tggttagtcg
     5521 aggattttct ggtaaattta ttacatgtta tccaaatcaa aatgaattag agtcggtttt
     5581 gcaaaggtta gaaagtgcct taaagcaata taatgggcca tatattttaa gcgataaacg
     5641 ttgggatgaa gcaccaatat atctgaggta tggtgtgttt aggccgtcaa gggatgatga
     5701 aaagaaggtt gttattgatg aattaattgt tggcgatgaa gttgttaaag atgaacgttt
     5761 accagtattt aaaattccaa aaggtatagt gccccctgac tttttgaata aatggcttga
     5821 caagaaagat aaaaaacagg gagactttcc ctttattata gataatgcaa ttagattttc
     5881 aaacagtggt gggatatata atgctagact aaaagaagat gggaaaaaaa taattttaaa
     5941 agaggctaga ccgtatacag gtctaggatt tgatggtact tattcttcag agagattagc
     6001 ttcggagtgc aaagcactaa aaattctaaa tgaatggagt gagatgccta aaatatactg
     6061 gtacggtaag atctgggagc acaccttctt aggaattgaa catatgaagg gcgttccact
     6121 aaatagatgg gttaccaata attttccttt atatgaagtt gttgataaga ccaaagatta
     6181 tctattgaga gtttcaaaga tagtagaaaa actcatcgat ttaacgaata agtttcattc
     6241 tgaaaatgta tatcatcaag atttacattt aggaaatatc ttggttaagg atgaagatga
     6301 gattagtata atagactggg aacaggctgt cttttcgaat gatgaaaaag ttgtacataa
     6361 agttgcagcc cctggtttta gagcatggcg agaaacactt cccagtgaga tagattggta
     6421 tggtattaga caaatagctc attatttata catgccacta gtaactacat cggatttgac
     6481 atacaactat gtaagtcaaa ccaggataga aggaaaaaaa ctatttgagt ctttgggtta
     6541 tacaagagaa catatagatt atgtagaaag tttattgtca tatctagatt ctaaatgtcc
     6601 acagattgag aatatttcca ggaaaaaagt tttaaaaccc atgcatgaga ttagaactat
     6661 cgagagtgag caagatatac aagattttat tataaaagct tttcttttag tgaactgata
     6721 ggtattttct tagcaaacga taaagtttta gggccgatac aatcaattgc ctattcatta
     6781 aataagataa atacaaccaa agatttaagg aaaccgtttt taaaatactt aagtggagag
     6841 aagaatttta tagacgctga acatgataat aacggactgt atacttcatc aatagatgag
     6901 atacacatga aagatgttgt atattctatt acaccagaaa ataaattaag tattgacttc
     6961 tcatttaagt caccatttag ggtattatta acaggaactt ctggtagtgg gaaaacaacg
     7021 attttaaatt taattaatgg ttctttaaag ccacaaaaag gttatgtaaa tttgttatca
     7081 catgggaaaa agagttcaga ttcaatacca acagttgatc agacaccata tatttttgac
     7141 actactattc gtgagaacgt aactttattt caaaatgaat atttttcaga tgatcagata
     7201 attgaggtgt taaaaaaggt aaatctatat gaagaattag aaaagataga tatactaaat
     7261 tatcaatgtg gtgaaaatgg tagtaatttg tctggaggtc aaaaacaaaa aatagcttta
     7321 gctagagctc tgattagaaa taataaagtg tacttatttg acgaaatatc agctaattta
     7381 gataatgata attcaaattc catacatgat attctgttca atttaggtat ttcatttatt
     7441 gaagtttcac atcattatga cttaaatgac aagagataca ctgatatata aattggaaaa
     7501 tggaacactt ttcaaaatta agtgattgga ggcaagaata tggataaaga ttatatatta
     7561 aaagtgaaag ggctgtatca tcaattttta ctgggaaaca ataaaacgtt gcaagtgctg
     7621 aaaaatgttt ctctttctgc ttcgagagga gaatttataa gtattctagg aattagtggt
     7681 tctggaaagt caactttatt aaaatgtatt tctagtttgc ttgaaccaac aagtggggaa
     7741 gtaattttaa atggaatcaa cccctataaa atcagaaatg caaaattatc aagtataaga
     7801 cgtaatgaag tatcttttat atttcaagca tataatttaa taccttccct gccggtaata
     7861 gaaaatatag cacttccttt gcgattatca caaaaaaaat taactattaa aaatgtagaa
     7921 aacttactca aaagaatgaa gtttaatgct ggcttaaacg attttgttgg aactctgtct
     7981 ggtggagaac aacagaaggt tgctatagct agagcggtta ttgctgatag tgatataata
     8041 tttgctgatg agccaactgg ggctttagac agcgtttctc gtgaagtaat ttttgaatta
     8101 ttgagagagt tagtaggggc gggtaagtgt gtaattatgg taacgcacga tatagaattg
     8161 gcctcgaaaa ctgatcgtgc attaatattg aaagatggaa aaattttcaa agaacttcat
     8221 agacctagcg gggaagagtt gtataaaatc ttagaggtac aatcaactac ggaggaatag
     8281 agatgctcag attagtttac tatcaatttt tacataataa gaaacaatgg ttaggcgttt
     8341 caccagtaat ttttgtttcg agtttagtta tgggattggc tgttaatggg gtaattaatg
     8401 ttgagaataa ttcgcaagta tttgtcggac ttccagatcc taaaccaatt tttatgtttc
     8461 cgatagtatt cggaggagta acattattct ttgtgctctc taacataata aatatgttgg
     8521 ttgaaatttt tagagatgat tacgaacttc tggaggtgtt gggagcaagt cgccttcaac
     8581 tatcatttct tgtgggggga cagattttta tcatttcctc gattattagt tttattgcat
     8641 atctatgctc tatatttgtt acgtcaaatt attattattt tttacaatac tttttcgggg
     8701 aaaatatatt acctgatatc caatttcaaa tgagtgctgt tggatgtatc attacagtag
     8761 tgttgatttc atttttagcc tttctaagtg gttgctttta tacgttcaag aagattagaa
     8821 ataggaagag ttctaaaata aggcatgttc tttcaatagt aaaaagaata ctgctattga
     8881 ctggttttag tgttatctgg ttgctttctt tgcaacaaat tttccaagat agcacaattt
     8941 tagcgaaggc ccagataata ttcaatattg taatcttaga tattgtgatt atttatcaat
     9001 tatctccttt tatacagtca tgttttatca aactactttc tataattata tttagaaata
     9061 attttatgtt cattgtttcg aagtggaatt tactatatcg taagccttat ataaaatcta
     9121 tcagtgctgc aattacagga gctatattac taatttctag ttttcaaatg atttctcaga
     9181 atatactatc tcaatttcaa gatgacagtg atttagagct aaaagtggca tttattgtct
     9241 atgtaggagc accaattttg atagtacttg caaatattat ttcaattgca tttttgtcat
     9301 cgcatcaaga aaggactgag attcagcaat ttgaaatttt aggaacttct aattaccaga
     9361 tggttaagat taaagttggt gaggctatat ttttgacatt tgttacttca ttaattgcat
     9421 ttttactta
//
LOCUS       DAVLZS010000064         8561 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLZS010000064 DAVLZS010000000
VERSION     DAVLZS010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8561
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.064"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..239
                     /locus_tag="VYO88_001811"
     CDS             <1..239
                     /locus_tag="VYO88_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HEV1719857.1"
                     /translation="KHLAGGDFQTLTIKRFRHLFLHVVGKYVRTGRKQLLKLSSLYAY
                     SELFSALYSRIRKVNLNLPVPYEPPGRKASLMMH"
     gene            417..626
                     /locus_tag="VYO88_001812"
     CDS             417..626
                     /locus_tag="VYO88_001812"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719858.1"
                     /translation="MNDLGKILLEIDLTVLIDLSCSYFVLIYSFEMVDRTDEVSSKHG
                     FEVVDKEKLMWFEEVFEECKKILVS"
     gene            907..3012
                     /locus_tag="VYO88_001813"
     CDS             907..3012
                     /locus_tag="VYO88_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1719859.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGNFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            3464..3685
                     /locus_tag="VYO88_001814"
                     /pseudo
     CDS             3464..3685
                     /locus_tag="VYO88_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(3971..4453)
                     /locus_tag="VYO88_001815"
     CDS             complement(3971..4453)
                     /locus_tag="VYO88_001815"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1719860.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(4548..6032)
                     /locus_tag="VYO88_001816"
     CDS             complement(4548..6032)
                     /locus_tag="VYO88_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1719861.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPGGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            6185..7792
                     /locus_tag="VYO88_001817"
     CDS             6185..7792
                     /locus_tag="VYO88_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1719862.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIARLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            7952..8125
                     /locus_tag="VYO88_001818"
     CDS             7952..8125
                     /locus_tag="VYO88_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV1719863.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFGGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(8118..8561)
                     /locus_tag="VYO88_001819"
                     /pseudo
     CDS             complement(8118..8561)
                     /locus_tag="VYO88_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2599 a         1587 c         1957 g         2418 t
ORIGIN      
        1 tcaaacatct agctggaggt gacttccaaa ctttaacaat caaacgcttc cgccatcttt
       61 ttcttcacgt ggtgggaaaa tatgttcgaa caggacgcaa gcagctcctc aaattgtcta
      121 gtctctatgc ctattccgaa ttgttttcag cactttattc taggattaga aaagtcaacc
      181 tgaatcttcc tgttccttat gaaccacctg gaagaaaagc gtcgttaatg atgcattaaa
      241 gaacagtcga gatgaaaaaa tcgtgtgacg caccaaggga ggagtctgcc cttttgagga
      301 aatctagcga ggaaaaacga tactggaaca gcagaaagta aaactgacct catgaggagg
      361 aagaaagtgg ctcatgaggt caggggtttt gtaagttaca tctagttgag agaggtatga
      421 atgatttggg taaaatattg ttagaaatcg atttgactgt cctgattgat ttgtcctgtt
      481 cttatttcgt tttaatatac agttttgaga tggttgatag aactgacgaa gtcagctcaa
      541 aacacggttt tgaggttgta gataaggaga agctgatgtg gtttgaagag gttttcgaag
      601 agtgtaaaaa aatattggtc agttaaagtc aaaacccttg accttttctg accaatgtag
      661 tatattatga acgtaaggta aatgaaagcc ttactagaac acttatttaa agtaaaatag
      721 aaagaggtgg gtctatgttt catctagaaa ttttcagaag taaagatggt ctactcctgc
      781 ttgaaaaaga aaaaccagaa atagtacgta gggtagcggt ttagctagtc taaatttttt
      841 aaaacaaagg tcaaagatag tcaatatcag taatcataac taagtaaaca aaaagaggta
      901 aagaatatga ataacaactt taataatttt aataacatgg atgatttatt taaccaattg
      961 atgggtggta tgcgaggata cagttctgaa aatcgccgtt acttaattaa tgggcgcgaa
     1021 gtcacacctg aggaatttgc tcactatcgt acgactggtc aattaccagg aaatgcagaa
     1081 actgatgtgc aaatgtcaca acaggcatca ggtatgaaac aagacggtgt ccttgcaaaa
     1141 ctaggtcgaa acttgacagc agaagcgcgt gagggtaagt tggatcctgt tatcggacga
     1201 aacaaggaaa ttcaagaaac atctgaaatc ctctcacgcc gcaccaagaa caatcctgtt
     1261 ttggtcggag atgcaggtgt tggtaagaca gcagttgtcg aaggtctagc gcaagccatt
     1321 gtgaacggag atgttcctgc tgctatcaag aacaaggaaa ttatttctat tgatatctca
     1381 ggtcttgagg ctggtactca ataccgtggt agctttgaag aaaatgtcca aaacttagtc
     1441 aatgaagtga aagaagcagg gaatattatc ctcttctttg atgaaattca ccaaattctt
     1501 ggtgctggta gcactggtgg agacagtggt tctaaaggac ttgcggatat tctcaagcca
     1561 gctctctctc gtggagaatt gacagtgatt ggggcaacaa ctcaagacga ataccgtaac
     1621 accatcttga agaatgctgc tcttgctcgt cgtttcaacg aagtgaaggt caatgctcct
     1681 tcagcagaga atacttttaa aattcttcaa ggcattcgtg acctctatca acaacatcac
     1741 aatgtcatct tgccagacga agtcttgaaa gcagcggtgg attattctgt tcaatacatt
     1801 cctcaacgta gcttgccaga taaggctatt gaccttgtcg atgtaacagc tgctcacttg
     1861 gcggctcaac atccagtaac agatgtgcat gctgttgaac gagaaatcga aacggaaaaa
     1921 gacaagcaag aaaaagcagt tgaagcagaa gattttgaag cagctctaaa ctataaaaca
     1981 cgcattgcag aattggaaag gaaaatcgaa aaccacacag aagatatgaa agtgactgca
     2041 agtgtcaacg atgtggctga atctgtggaa cgaatgacag gtatcccagt atcgcaaatg
     2101 ggagcttcag atattgaacg tttgaaagat atggctcatc gcttgcaaga caaggtgatt
     2161 ggtcaagata aggccgtaga agttgtagct cgtgctatcc gtcgtaaccg tgctggtttt
     2221 gatgaaggaa atcgcccaat cggcaacttc ctctttgtag ggtctactgg ggttggtaag
     2281 acggagcttg ctaagcaatt ggcactcgat atgtttggaa cccaggatgc gattatccgt
     2341 ttggatatgt ctgaatacag tgaccgcaca gctgtttcta agctaattgg tacaacagca
     2401 ggctatgtgg gttatgatga caatagcaat accttaacag aacgtgttcg tcgcaatcca
     2461 tactctatca ttctcttgga tgaaattgaa aaggctgacc ctcaagttat tacccttctc
     2521 ctccaagttc tagatgatgg tcgtttgaca gatggtcaag gaaatacagt aaacttcaag
     2581 aacactgtca ttattgcgac ctcaaatgct ggatttggct atgaagccaa cttgacagaa
     2641 gatgcggata aaccagaatt gatggaccgt ttgaaaccct tcttccgtcc agaattcctc
     2701 aaccgcttta atgcagtcat cgagttctca cacttgacta aggaagacct ttctaagatt
     2761 gtagatttga tgttggctga agttaaccaa accttggcta agaaagacat tgacttggta
     2821 gtcagtcaag cggctaaaga ttatatcaca gaagaaggtt acgacgaagt catgggggtt
     2881 cgtcctctcc gtcgagtggt tgaacaagaa attcgtgata aggtgacaga cttccacttg
     2941 gatcatttag atgctaaaca tctggaagca gatatggaag atggcgtttt ggttattcgt
     3001 gagaaagcct aagacagaat tttgaggata aaaaagaagg agccagctga aaaaaactgg
     3061 ttcctttcta ggtacgacgg gcatgtcgtg tagtaggttg aaactagaat agtacacatc
     3121 tacttctaaa acatttttag aaatcgattt gactgtcctg attgatttgt cctgttctta
     3181 tttcatttta ctatatatct gaggtgtaag tcctcggtgg gtacctgcta ccggtgctcc
     3241 caatagtgat tcccaagcct gactatcgtg aggtagcgga ttaaaacggt ctggggatag
     3301 accgttttaa gtctgacgct ggaaataaga atcgtcagag gaagggatag cgaaatcgtg
     3361 gctctacgaa taggaacgtg ataataaggc gtatatagcg gataaggggc ctcaaactct
     3421 aaagttcaaa aaggtagtcg taacctatat gcgtaaatca cgagagcaac tgaatttgtc
     3481 cattcgagga tggataaact atttctcatt gggaaatatg aaaagtatag tcaccagcat
     3541 agatgagcgt ttgcatactc gcctacgagt gattatctgg aagcaatgga agaagaaatc
     3601 gagacgatta tggggattgc ttaagttagg ggttcctaaa tggatagcag ataaggtatc
     3661 tggctggggc gaccactatc aattatagta aaatgaaata agaatagaac aaatcgatca
     3721 ggatagtcaa atcgatttct aacaatgttt tagaagcaga ggtgaactat tctagtttca
     3781 atccactata gtagctcaga agtcggtact taaacgtgct atatcaaaac cagtccttga
     3841 aaaacgtgga ttggtttcgt gtttggatta ttaccttgaa cgacatgcgt taaaagttag
     3901 ttgaaccgcc gtatgccgaa cggcacgtac ggtggtgtga gaggggctag agattatccc
     3961 ctactcgatt ttaaatcaca tgacgttcaa aggcatcatc tgaaatccct tgttccaaga
     4021 tgagttttgc ccattcttta gcagagaaga ggctgtggtc cttgtagttt ccgcaagatt
     4081 cgatggttgt ccctgggaca tcttcccaag tagtagtttc agcgatttcc ttgagcgaat
     4141 ccttgataac agctgcgatt ttagcactgg tgtgacgtcc ccacataatc atgtggaagc
     4201 ctgtgcggca accaaatggt gaacagtcaa tcatgccgtc aatgcgggta cggatgagtt
     4261 tggctaagag gtgctcgata gtgtgaaggc cggcagtagg gatagagtct tcgtttggtt
     4321 gcaccaagcg aatatcataa ttggagatga tgtctccttt tggtcctgtt tcttccccaa
     4381 tcaagcgaac atagggtgct ttgacaatgg tgtggtcaag ttcaaaactt tcgacaataa
     4441 cttcttttga catggtaaat cctttcagtt ttcttctctc attatatcat aaaggttgtt
     4501 cctgagacag agagaaaacc tctccgaggc tagagaggtt gaaatcttta cttacgatat
     4561 aagcggtcgt attggtagta tgggtcaaag gttacgttga tacccagttt acgaaggaca
     4621 ttcttgtctt catcagtcaa gatgatggtt gagtgggctt cgcttccttt gaggttgccg
     4681 agttcttcca tagcgcgggc agcatcagga ttttctgtag ctgtgatagc aagtgcaatc
     4741 aggatttcat ttgaatgaag gcgtggattg cggctaccga gatgatcgat tttaagacct
     4801 tggatcggct taacaacttc aggttcgatt agttttactt ctttagcgat gtcagctgat
     4861 tttttgatgg cgttgatcaa ggcagcggct gtaggaccaa agagttctga gttcttacca
     4921 gtgacgattt ccccatttgg caattcaaag gctagggctg gtccaccagt ttcttctgct
     4981 ttttggcgcg caacgacagc aaccttacgg tctgcaggtg tgataccgag gtcgttcatg
     5041 agcaactcaa ttttcttgac ggcagcttcg ccaacttttt cagctttgaa gtcaagaact
     5101 gtttgatagt aacggcggat gatttcttgt ttagaagctt cgacagcggc ctcgtcatct
     5161 gtaatagcga aaccaaccat gttgacaccc atatctgtcg gtgaagcgta tggtgatttt
     5221 ccgagaatac gttccaacat gcgtttgagc actgggaaga tttcgatatc acggttgtag
     5281 ttgacagtgg tttctccata ggtttgaaga tggaaggggt caatcatgtt gacatcatca
     5341 aggtcagctg tggcagcttc ataagccaag ttaactggat gatgaagggg aagattccaa
     5401 acagggaagg tttcaaattt agcgtagcca gatttgatgc cattgatttg gtcgtggtac
     5461 atattggaca tacacgttgc caattttcca gaaccgggtc caggagcggt tacgacaatc
     5521 aagttgcgac tggttttgat gtagtcgttt ttgcccatgc ctcctgggga aatgatgtga
     5581 tccatatccg taggatatcc tttgattgga taatgaagat aagaatcaat tccgtttttc
     5641 tcaagttggt tgcggaaggc atctgcagcg ggttggccag cgtattgtgt aatgacaacg
     5701 gaaccaacaa aaatccctaa ttcattgaat ttgtcaatca aacgaagaac ttcttggtca
     5761 taagaaatgc ctaagtcgcc acgtgctttg gaatgttcaa tgttgctagc attaatggca
     5821 atcacaacct caacctgctc tttcaattct tgcaagagct tgattttgtt gtcaggttca
     5881 taaccaggaa ggacacgagc agcgtggaaa tcttctaaca ttttaccgcc aaactctaag
     5941 tagagcttgc cgtcaaattg gttaatgcgc tccaaaatat ggtcgcgttg taaattcaaa
     6001 tactgttcag aactaaaagc ttgttttttc atttttttac ctctggactc tattataata
     6061 aaaaattgga agttaggaaa ctacggagct aaaaaagaaa ttaaaaagat taagcaaacg
     6121 attgcacaaa attttaaaaa gtgctatcat agactataga ttattaaaat aatgaggtaa
     6181 acagatgcaa gaaaaatggt ggcataatgc cgtagtctat caagtctatc caaagagttt
     6241 tatggatagt aatggagatg gagttggtga tttgccaggt attaccagta agttggacta
     6301 tctagctaag ttaggaatca cagcgatttg gctttctccc gtttatgaca gccctatgga
     6361 tgataatggc tacgatattg ctgattatca agcgattgcg gctatttttg gaaccatgga
     6421 ggacatggat cagctgattg cagaagctaa gaagcgtgat atccgtatca tcatggactt
     6481 ggtggtcaat catacctcgg atgagcatgc ttggtttgtc gaagcctgtg aaaatactga
     6541 cagccctgag cgagactact atatctggcg cgatgaaccc aatgacctag attctatctt
     6601 tagtgggtct gcttgggaat acgatgaaaa gtcaggtcaa tactatctcc actttttcag
     6661 caagaaacag ccggatctca actgggaaaa tgaaaaactt cgccagaaaa tttatgagat
     6721 gatgaacttc tggattgata aaggtattgg tggtttccgt atggatgtta ttgacatgat
     6781 tggcaaaatt cctgacgaga aggtagtcaa taatggtcct atgctccatc cctatctcaa
     6841 ggaaatgaat caggcgacct ttggagataa ggatctcttg acagtagggg agacttgggg
     6901 agcaacgcca gagattgcca ggctctactc tgatccaaag gggcaagaat tgtctatggt
     6961 cttccagttt gaacatatcg gtcttcagta tcaggaaggt cagcctaaat ggcactatca
     7021 aaaagagctg aatatcgcta agttaaaaga aatcttcaac aaatggcaga cagagttagg
     7081 agttgaggac ggctggaatt ccctcttctg gaacaaccat gacctccctc gtattgtctc
     7141 aatctgggga aatgaccaag aataccgcga aaaatctgcc aaagcctttg caatcttgct
     7201 tcatcttatg agaggaactc cttatatcta ccaaggtgag gagattggga tgaccaacta
     7261 tccgtttgaa acactggatc aagtagaaga tattgaatct ctcaactatg cgcgtgaggc
     7321 tcttgaaaaa ggtgttccga ttgaagaaat catggacagt atccgtgtta ttggacgtga
     7381 caatgcccgt acccctatgc aatgggacga gagcaaaaac gctggtttct caacaggtca
     7441 accttggttg gcggttaatc caaattacga gatgatcaat gtccaagaag cgctggcaaa
     7501 tccagattct attttctata cctatcagaa actggtccaa attcgcaagg agaatagctg
     7561 gctagttcga gctgactttg aattgcttga tacggctgat aaggtctttg cttatatacg
     7621 taaggatggc gaccgtcgct tcctagttgt ggctaacttg tccaatgaag agcaagactt
     7681 gacagtagaa ggaaaagtca aatctgtctt gattgaaaac actgcggcta aagaagtact
     7741 tgaaaaacag gtcttggctc catgggatgc tttctgtgtg gaattactat aaatattttt
     7801 tgcagaaaaa tttaaaattg aaatcatata aaaacaaggg aggactgtat aaaagacaga
     7861 aatcctttgt tttttataac caaggtttat aaactttcat tctcgaaatt caattaactt
     7921 tacaaattcc cactatttaa ggagaaagaa gatgaacata aagaagcgag tccttagtgc
     7981 aggcctgact tttgcatctg ctttgctttt agctgcttgc ggccaatcag gttcagatac
     8041 aaaaacttac tcatcaacct ttggtggaaa tccaactaca tttaactatc tattagacta
     8101 ttacgctgat aacatagtca attgaaacaa gaacaggaca aaagagcctc ataaaaggta
     8161 ttgcaacttg gtaatacctt ttacgaggct ttttgatatg agcccatgtt ttctcaatag
     8221 gattgtactc aggtgagtag ggaggaagag gtaaaagttt atacccaaac tcttcacaca
     8281 agagttctaa cttacccatt ctatggaatc ttgcattatc cataataata accgatggtg
     8341 tggttaatgt tggtaagaga aacttctgaa accaagcttc aaaaaagtcg ctcgtcatca
     8401 tctcttcgta agtcattgga gcgattaact caccattcat ttgttagacc tgcaaccaaa
     8461 gaaattctct gatatcttct tccagatact ttgcctctta ttaactgacc ttttaatgag
     8521 cgaccatatt ctcgataaaa ataagtatcg aatcctgttt c
//
LOCUS       DAVLZS010000065         8531 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLZS010000065 DAVLZS010000000
VERSION     DAVLZS010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8531
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.065"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..283
                     /locus_tag="VYO88_001820"
     CDS             <1..283
                     /locus_tag="VYO88_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV1719864.1"
                     /translation="LHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELSINMEK
                     KIMNYIFEDDGNVSEVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            296..1771
                     /gene="galT"
                     /locus_tag="VYO88_001821"
     CDS             296..1771
                     /gene="galT"
                     /locus_tag="VYO88_001821"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1719865.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1784..2764
                     /gene="galE"
                     /locus_tag="VYO88_001822"
     CDS             1784..2764
                     /gene="galE"
                     /locus_tag="VYO88_001822"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1719866.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            2974..3633
                     /locus_tag="VYO88_001823"
     CDS             2974..3633
                     /locus_tag="VYO88_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1719867.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3658..4725
                     /locus_tag="VYO88_001824"
     CDS             3658..4725
                     /locus_tag="VYO88_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1719868.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4829..5839
                     /locus_tag="VYO88_001825"
     CDS             4829..5839
                     /locus_tag="VYO88_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719869.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIVDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETKQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5851..7542
                     /locus_tag="VYO88_001826"
     CDS             5851..7542
                     /locus_tag="VYO88_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1719870.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTECFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7545..8255
                     /locus_tag="VYO88_001827"
     CDS             7545..8255
                     /locus_tag="VYO88_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1719871.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            8351..>8531
                     /locus_tag="VYO88_001828"
     CDS             8351..>8531
                     /locus_tag="VYO88_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719872.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSM"
BASE COUNT         2895 a         1167 c         1671 g         2798 t
ORIGIN      
        1 acttcatgaa gttatcggac tgcatatgaa tagggctata tcttgttata gagaggaaca
       61 atctggatgt ttagatatgg ttgttataca aaaacagaat gagatagaag agcttagtat
      121 aaatatggaa aagaaaataa tgaattacat atttgaagat gatgggaacg tttctgaagt
      181 aattagtgct ttagatatta ttcatcacct tgataaaatt gctcatacta cgcaagcaat
      241 ttataaatgg ataatgtata gaaaatatgg gaacataaat tagaaagaaa aatatatgaa
      301 aacaattatt gataattttg ttgatagagt aattgaatac ggaatgtata atgaaattga
      361 caaaatatat gtgaaaaata gagtactagc gttaataggt gaggagggaa ttgatcgcat
      421 ttccgatgaa aatgacctga aacaaataaa agattactta gtggaaatcg ccttaaaaaa
      481 cggtaaaatt aaagatttaa tcgaggaaaa ggaatgttta ggagcagagt taatgaattt
      541 catagttcct ttacctagtc gattaaatga tattttttgg agttcatatg atatatcacc
      601 tcaagaagca gttgaagagt tttataagtt aagtaaagat agtgattata ttaaaacttc
      661 tgctattgct aagaatattg agtttcgagc atcaactaaa tacggagagc tagagattac
      721 gataaatttg tcaaaacccg aaaaagatcc aaaaacaatt gctgctgaaa aattagtaaa
      781 agcaactaat tatcccaaat gtttactatg tatggaaaat gaaggatatc aggggcgaat
      841 aaattatcca gcacgttcga atcatagaat tattcggttg aaacttggtg acgaagtatg
      901 gggattccag tattctccct actcgtactt taatgagcat gcgatatttt tgaatagtca
      961 acatgtacca atggctatta cctctaaaac atttgaacaa ttattggaga ttgttgatat
     1021 tttgccagga tattttgctg gttcaaattc tgatcttcct atatcaggag gctccattct
     1081 tagtcataac cactaccagg gagggaaaca tattttccca atggaaaaag caaaatttga
     1141 gagtgaattt tgttttaaag actttgagga tgttaatgct ggtattgtaa aatggccaat
     1201 gtcagtaatt aggttacaaa gtgaaaataa aaatcgcttg ttagatttag ctactaaaat
     1261 tctaaataag tggagagaat attcagattt agaagtagac atcattgcta tgactgaaga
     1321 tgtcccacac catacggtga ctcctattgc tcgtaaagtg gacgggagat acgaattaga
     1381 tattgttcta agagataatc atactactga acaataccca gatggtgttt tccatcctca
     1441 tcaagatgta caacatatta aaaaggaaaa tatcgggtta atcgaagtga tgggacttgc
     1501 gatattacca cctcgtttga aaccagagtt agaagaagtt ggaaaatatc ttttaggaga
     1561 ggataatgca attgcggatt atcatttaga atgggccgac caattgaaag aaaaatatcc
     1621 tcgcattaat aaagaagagg ttaatagcgt agttcaacac gaagcaggac aagtgtttgc
     1681 gagagttctg gaagatgcag gagtttataa gaatacaccg tctgggcatg aagcgtttat
     1741 gagatttgtt aagtcggttg gaattaatta ggaggaaacc cagatggcaa tattggtaac
     1801 aggcggagct ggttatattg gtagccatac cgtagtagaa ttactaaatt taggaaagga
     1861 agttatcatt gtcgacaacc tttcgaactc tagcaaattg gtgctagacc gtattgaagc
     1921 aattacagga atacgtcccg tgttttacga attagatgtt tgtgataaac aagcattgag
     1981 aaaggtattt gaacaagaat cgattgatgc tgcaattcat tttgcaggtt ataaagctgt
     2041 cggagaatcc gtgcaaaagc ctgtgatgta ctacaaaaat aatattatga gtacattggc
     2101 acttgttgaa gtgatgtcag aatttaatgt taaaaagatt gtcttttctt caagtgcgac
     2161 tgtatatgga attaacaatc agtcacctct aattgagacg atgcaaacaa gtgcgacaaa
     2221 tccttatggg tatacgaaag tgatgcttga gcaaatttta aaagatgttc atgtggcaga
     2281 ttcagaatgg agtattgcgt tgcttcgtta tttcaatcca attggtgctc atgagtctgg
     2341 tttgattggg gaagatccct caggaattcc taacaacttg atgccttata ttgcacaagt
     2401 agcggtaggt aagctatcag agctaagtgt gttcggcaat gattatgata cgcttgatgg
     2461 tactggtgtg cgtgattata tccatgtagt agatttagca ataggacata taaaagcttt
     2521 agaaaaagta tctgaaaaaa cagatgttta tatctataac ctaggctcgg gagaaggcac
     2581 tagtgtatta caacttgtaa atacatttga aagtgttaat aagatcccta ttccttataa
     2641 aatagttcca agacgttcag gagacgttgc aacttgttat gcaaatgcag acaaagcata
     2701 taaggaatta aattggagga caacaaaatc gattgaagac atgtgtagag atacatggaa
     2761 ttagcaatca aaaaatccca atggctataa ttgatgatac tgtctatatg agtgctgtat
     2821 tttggaaaaa ttacttaacc ttttaatgaa atgcatattt aatgaaagat aaattaaaaa
     2881 aaatgtttga cagcgcttga caaaggaaac ggtttcattg tataatgtaa acataatgac
     2941 accgatgtca aatataaaaa agaaggtctt tatatgaaaa acttaacaaa aattaagttc
     3001 aaagagaatg gggaatttaa tcatttccct gggaatacag ttgtagcaaa tctttatact
     3061 aaacaagatt tgatggaagt tgttgatatt attcaatcac gttatagaga attaccattt
     3121 atcgataagt ttactttaac tccaaggaat tctattcaca tgactgtaat tgaattgttg
     3181 tgccatgaaa atcgtgaaac ggagttttgg agcagtaatc ttcctctaga tacaccttta
     3241 caggaaatac atgattactt tgctaaacaa cttgaaattt ttccattgtt ggatgaagaa
     3301 attcatatgc gtataactga aatgggaaaa caaaacatac tagttgaacc tgcagatgaa
     3361 gcttctgcaa agagattaga agaaattcgt acttatgtct cagaaaaagc aggtgtttgt
     3421 ttccctaatc atgatagata tcaattccat atttcaattg ggtatcttcg gattcctcta
     3481 accgaagagg aggaagaaga gtttactaaa gtcagagcag aattaactga aattttatta
     3541 gagaagattc caactattac tgtaaaccgt attgactata ctgtatttga agatatgaga
     3601 caatttgttc catatcacga aaaatttaaa taaaataata aaaaaggaga acttatcatg
     3661 aaaaaaatga aagtttggtc tactgtactt gcaacgggag ttgctcttac tacacttgct
     3721 gcttgctctg gaggttcaaa ttctacgact gcttcttcat ctgaagaaaa agctgataaa
     3781 agtcaagaat tagttatcta ttcgaactca gtctcaaatg gtcgtggtga ttggttaact
     3841 gctaaagcaa aagaagctgg ttttaatata aaaatggttg atatcgctgg cgctcaatta
     3901 gcagaccgtg ttattgctga gaagaataat gcagttgcag atatggtatt tggaattggt
     3961 gctgttgact caaataaaat tagagatcaa aaattactag tacagtacaa gcctaaatgg
     4021 ttagataaaa ttgatcaatc tttatcagat aaagataatt attataatcc tgtgattgtt
     4081 caaccattag ttttaattgg ggcgcctgat gtaaaagaaa tgcctaaaga ttggactgaa
     4141 ttaggtagta agtataaagg taaatattca atttatggtc ttcaaggtgg tacaggacgg
     4201 gcaattctag caagtatctt agttcgttac cttgatgaaa aaggagattt aggcgtatca
     4261 gaaaaaggat gggaagttgc aaaagaatac tttgcaaatg cctatactct tcaaaaaggt
     4321 gaaagctcag ttgttaaagc gttagataaa gaaagcccaa ttcaatacgg tatgatctgg
     4381 ggttctggag cgttaattgg acaaaaagaa caaaatgttg aattcaaagt tatgactcct
     4441 gagattggtg taccatttgt aactgaacaa actatggttt taagcactag taaaaaacaa
     4501 gcgttagcta aagaatttat tgattggttt ggtcaatcag aaattcaagt agaatatagt
     4561 aaaaaatttg gatctattcc tgcaaataaa gatgccctaa aagagttacc tgaagatacg
     4621 aaaaaatttg ttgatcaagt gaaaccacaa aatattgact gggaagctgt tggaaagcat
     4681 ttggatgaat gggtagaaaa agctgaatta gaatacgtaa aataagaaat aagagttatt
     4741 ttttatgtcc aagtctctct attatttcta aatttaagga agaaataaag agaggctttt
     4801 ggttttagta atagagggag ttagtgagat gattaaattt gataatattc aaattaaata
     4861 tggtgatttt gttgcaattg ataatctgaa tttagatata catgaagggg aattctttac
     4921 atttcttggg ccttcaggat gtggtaaatc aactactttg agagcattgg taggtttttt
     4981 agatccatca tcaggaagta ttgaagttaa tggaacagat gtcactcatt tggaacctga
     5041 aaagcgtgga attggtattg tatttcaatc ttatgcgcta tttccaacta tgactgtttt
     5101 tgataatatt gcatttggtt taaaagttaa gaaggtagct ccagatgtta ttaaagctaa
     5161 agtatcagca gtggcagcaa aaattaagat ctctgatcaa cagttacagc gtaatgtatc
     5221 agaattatct gggggtcaac aacaaagggt agcattggct cgtgctctgg ttcttgaacc
     5281 taaaattctt tgtctagatg aaccattgtc aaaccttgac gcaaaattac gtgtagattt
     5341 gagaaaagag ttgaaaagac ttcaaaaaga gttaggtatt actactttat atgttactca
     5401 tgatcaagag gaagccttga ctttatctga tagaattgca gtctttaaca atggatacat
     5461 cgaacaggtc ggtacaccag tagagattta tcataattct caaactgaat ttgtatgtga
     5521 ttttattgta gatattaatg ttttgaccga tgaaacagtc cacgaagtat tactgaaaaa
     5581 tacaagcgtt ttcttagaag ataaaaaagg ttacattcga ttagagaaag ttcgattcaa
     5641 tcgtgaaact aaacaagatt ttattctaaa agggacaatt attgatgttg agttttctgg
     5701 agttacaatt cactatacaa taaaagtttc tgaaagtcag attcttaatg taacaagtat
     5761 tgatagtcag gctgctatta gatctgtcgg agaaagtgtg gaattattta tcacaccatc
     5821 agacgttctg caattttaag gaggtgcagt atgcgtcata aattaaattt aaaagattgg
     5881 cttattcgtt tagggttaat ctggttctta gtaacattta ttatttatcc aaactttgat
     5941 ctagtagtga atgtatttgt aaaaggagga gaattttccc ttgatgctgt acatcgtgtt
     6001 ctaaaatctc agagggcact tcagagtatt atgaacagtt ttaagttagc attttcactc
     6061 attattacag ttaatgtcgt aggtattctt tgtgttctat ttacagagtg ctttgatatt
     6121 aaaggtgcta aaattttaaa attaggttat atgacctctt taatttatgg aggagtggtt
     6181 ttagcgactg gatataaatt tgtctatggt ccttatggat tgattacaaa atttttacaa
     6241 aatgttatcc cttctttaga ctctaactgg tttattgggt atggtgcagt cttattcatt
     6301 atgacatttt caggaactgc taatcataca ttgtttttaa caaatacaat tcgaagcgtt
     6361 gactatcaca ctattgaggc tgctcgaaat atgggagcaa aaccatttac tgttttccga
     6421 aaagtagtgt taccaacctt aattccaact ctatttgcac ttactattat ggtttttctt
     6481 agtggtttat ctgcagtagc agcacccatg attgttggtg gtaaagaatt tcaaactata
     6541 aatccaatga ttattacatt tgcagggatg gggaattctc gtgatttagc tgccttactt
     6601 gcaattattt taggtattgc aactacaatt ttgcttacta ttatgaataa gatagaaaaa
     6661 ggtggaaatt atatttctat ctctaagact aaagcgcctc ttaaaaaaca aaaaattgcg
     6721 tctaagcctt ggaatatcat tgctcacatt gtagcatatg gattgttcac agttttcatg
     6781 cttccactaa tttttatagt attatactca tttacagatc cagttgcaat tcaaacaggt
     6841 aacttaacat tatcaaactt tactttagaa aattatcgct tattctttag taatagtgcg
     6901 gcattctctc cattcttggt cagctttatt tattctatta ttgctgcgac aacagcaaca
     6961 attctcgcag ttgtatttgc tcgtgttgtc agaaaacata aatctcgttt tgatttctta
     7021 tttgaatatg gtgctctact tccttggtta ctaccaagta cacttttagc agtaagttta
     7081 ttatttactt ttaatcagcc acaatttctt gtcttgaatc agattttggt aggtagtttg
     7141 gtaattctac ttattgcata tatagttgta aaaatcccat tttcttatag aatggtacgt
     7201 gctattttat ttagtgttga tgatgagatg gaagatgcag caagaagtat gggtgcttca
     7261 cctttttata ctatgatgaa ggttatcatt ccatttattt taccagttgt tctctctgtt
     7321 attgctttaa actttaactc tttattaact gacttcgact tatctgtatt cctttaccat
     7381 cccctagctc aaccattagg tattacgatt cgatctgcag gtgatgaaac agcaacatct
     7441 aatgcacaag ctctggtatt tgtttataca attgttctga tgattatttc tggaacggta
     7501 ttatacttca cacaaagacc ggggcgtaaa gtaaggaaat aatcatgaca gccactagtc
     7561 ttgggttatc aaatattgaa atagttgtca ggattgtttt atcagtagtc attggtagta
     7621 taattggttt agagagaggg agcaaatccc agcctgcagg catccgaact tatagtattg
     7681 tttgtctagc tgcatgtttg attatgatga cgaatgaata cgtatcttat aaatttggga
     7741 caggagatcc tacacgatta ggagctcaag ttatatcagg tgtgggtttt ctaggcgctg
     7801 gaacgattct tattacagat aaaaagaaaa ttacaggtct gacaactgca gcaggcattt
     7861 gggcttcggc aggaattgga ttagctattg gagtaggttt ttatgaggga gctcttttag
     7921 tagccatttc tgtttggggt gtgatatcca tgttccaacc actaaaaaaa tatctgcaaa
     7981 atcgttctaa aatgattgaa ttgtatatag tggttaaatc tacagaagcc tataatcgtg
     8041 tattggttta ttgtgcagaa aatggtatca gaatgaccga ttcaagaaca gcgtttggag
     8101 atgttaattc tgacagaatt gaatactttg atgttccgga caaaaaaata gcgtcattta
     8161 ttactctgga attatcaggt agatttgaac atcttcgact gatggaagaa attgctaata
     8221 ttgtaggtgt tatttatgtc gaagaaatta gctgaaattt agtaaacaaa gggacagatg
     8281 tttttgtcct tttgtttttt agatgtttta atcatctaat ttttgagtag atttttgctc
     8341 agaggttttt atgaaagatt ataaaatcaa ttttgattta ggtaaaatag aatattttga
     8401 taataattgt ttgatacaag tatacaaatt tatttctttt tatgatattt gtgaaatggt
     8461 gtttgccttt catttacctc ctgatgagtt gataacaaat gttatcttta aagaaaaaat
     8521 taactctatg t
//
LOCUS       DAVLZS010000066         8459 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLZS010000066 DAVLZS010000000
VERSION     DAVLZS010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.066"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(426..1412)
                     /locus_tag="VYO88_001829"
     CDS             complement(426..1412)
                     /locus_tag="VYO88_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1719873.1"
                     /translation="MGKSVAILMTTYNGERYLSQQIDSIRSQTFTNWTLFIRDDGSKD
                     KTIEVIQRYSKIDDRIRLVENPSKFHGAYYNFFNLIEYVKNNYQFDYYFFCDQDDIWK
                     EHKLEIQLLRFSKDDMPEMVYSDMSTIDASNNLIDISINKIMGIELPNINNLYFIQAY
                     IWGCTAGFNHALLEMVPSVDIDKDYLYIEKLAHDSYFAKFALEYGKVLFCPEQLVLYR
                     RHGHNVTTSHHFKLSPLNVFRKAILGFNELALTHARVYNQTLYMLKKASGKNPLSDRL
                     LEIQEVIKIGGLKGVRYFYQNRISRKQLVRTIGLYTIMLFGAYKKYIMKELL"
     gene            complement(1415..2134)
                     /locus_tag="VYO88_001830"
     CDS             complement(1415..2134)
                     /locus_tag="VYO88_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HEV1719874.1"
                     /translation="MSIYKLCKDIERKTMSPAKKAMAKNDYFAFYVGRPLSYLLTVPF
                     VKTNITPNQISYLSIIPLIVGFIIMIFTTDFVVLLLAWFLFFLWNLLDGVDGNLARYR
                     EQYSKDGSVVDAMAGYVAMVLTYFGAGIVAAHLTDSDIYIILGALSGFSLIFPRLVMH
                     KYINTVAQDESVSSIKDKSDFNTIKILALNMTSITGIPQVLLLLTILTNQWVLFTLVY
                     FTINFLLMIFSLYSLFKKENV"
     gene            complement(2121..3245)
                     /locus_tag="VYO88_001831"
     CDS             complement(2121..3245)
                     /locus_tag="VYO88_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1719875.1"
                     /translation="MFMKLLHFSEVGGGVDRYIKLYLKYSDKEHFKNIVVGSDQLNRQ
                     TYEQEYNIKFYHIDIYRSLSPIKLLRAIKQFRKILYLERPDIVYLHSTFAGVVGRLAS
                     MGLSCKVVYNPHGWSFKMDVSKIKQFVYKNIEKFLSYLTDKYILISKSEYEAAQSLKI
                     PLKKLTLVYNGVEIDEDFNENQINVLLPINKYVIGMIGRISEQKNPFFFVEFAKKLSE
                     IYSNLYFVIVGDGELRGRTEELIEEYGLRSSFFITGWVDNPEDYLAQFNQAVLFSKWE
                     GFGLAVAEYMKHKKPILITNVDGMSELVIDGESGFKVPLYNLEVTVDRSRSIIENREL
                     ANELGSAAFQRVRSTFEIKEKVSELENIFMSLREDDNVNI"
     gene            complement(3252..4619)
                     /locus_tag="VYO88_001832"
     CDS             complement(3252..4619)
                     /locus_tag="VYO88_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1719876.1"
                     /translation="MNGKIVKSSLVIIQSSLVILLTYLLSTVREAKIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDGLIESNEVVGEL
                     VAVSVLDKPDFQHDYLKIVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIRKMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            complement(4634..5323)
                     /locus_tag="VYO88_001833"
     CDS             complement(4634..5323)
                     /locus_tag="VYO88_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1719877.1"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     LGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSIDKYGSY
                     GNYGNYGKNKK"
     gene            complement(5333..6025)
                     /locus_tag="VYO88_001834"
     CDS             complement(5333..6025)
                     /locus_tag="VYO88_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV1719878.1"
                     /translation="MKEQNTIEIDVFQLFKTLWQRKLMILLVALVTSAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDALEKVATNLKLD
                     MPAKTLASKVQVAVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLKIP
                     LLGLVPDFDKMK"
     gene            complement(6034..6765)
                     /gene="cps4B"
                     /locus_tag="VYO88_001835"
     CDS             complement(6034..6765)
                     /gene="cps4B"
                     /locus_tag="VYO88_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEV1719879.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            complement(6767..8212)
                     /gene="cps4A"
                     /locus_tag="VYO88_001836"
     CDS             complement(6767..8212)
                     /gene="cps4A"
                     /locus_tag="VYO88_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV1719880.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIKKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGDYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
BASE COUNT         2718 a         1763 c         1270 g         2708 t
ORIGIN      
        1 cctatagtta cttatcaaat ctgtaatatt agaaaaactt ctacctgaaa acaataccac
       61 tttctgaatt tcacgggtat aaagaaatag cataacaaga tttagaatca gaagaatgac
      121 atagattatc tttgaaggat ttatttcttt caattcttca tacgaaattc cctccacttt
      181 aggcctgtac gacaattttg tcaacaagga aactataata aatgtagcaa cccctaacaa
      241 tatcaaacca aaggttttga aatggagttc tgttccccaa acatttctat taactagagc
      301 acttgcaatc gaaataaaat aagtgagtgt taaaattact gcaggttgaa aaaaatcccc
      361 ctcaaataat ataaatgtaa tgataattaa tagaaaaata gatatgaata agaaatttaa
      421 aagcattata agagctcttt cataatatat tttttatagg ccccaaaaag catgatggta
      481 tataagccga ttgttcttac gagttgcttt cgagaaattc gattctgata gaaatatctc
      541 acacctttta atcctccaat tttgattact tcctgaattt caagtagtct atcacttaaa
      601 ggattttttc cagaagcttt ttttagcata taaagagttt gattatatac cctagcatgt
      661 gtaagtgcca attcattgaa acccaatata gcctttctga aaacatttag cggagataat
      721 ttaaaatgat gactagttgt tacattatgt ccatgtcttc gatacaagac cagttgttca
      781 gggcagaaca acaccttccc atactctagc gcaaactttg caaaataact atcatgagcc
      841 agtttttcta tatataaata atctttatca atatcaactg aaggaaccat ctctagcaat
      901 gcatgattaa aacctgcagt acacccccag atataggctt gaataaaata caaattattt
      961 atgttcggta attcaatccc cattatttta tttatactaa tatctatcaa attattactg
     1021 gcatcaatcg ttgacatatc agagtaaacc atctctggca tgtcatcttt agaaaatctt
     1081 aacagctgta tttctaactt gtgctctttc caaatatcat cttgatcaca aaaaaagtaa
     1141 taatcaaatt gataattgtt tttaacgtat tcaattagat taaaaaaatt gtaataagct
     1201 ccatgaaact ttgagggatt ttcaactaat ctaattctat catctatctt agaatacctc
     1261 tgtattactt ctattgtttt atcttttgat ccatcatccc taataaaaag cgtccaatta
     1321 gtgaatgttt gagacctaat actatcaatc tgttgtgaca aatatcgctc accattatag
     1381 gtggtcatta aaattgcaac tgactttccc atttctaaac attctccttt ttgaataatg
     1441 aatacaaaga aaatatcatt aataaaaaat taatcgtgaa atatactaaa gtaaaaagta
     1501 cccactgatt tgttaaaata gttaatagca gtaaaacctg cggaattcct gtaattgatg
     1561 tcatgtttag agccagtatt tttatagtat taaaatcgga tttatcttta atgctactca
     1621 cagactcatc ttgagctact gtattgatat acttatgcat cactaacctt ggaaaaatca
     1681 atgaaaaccc agataatgca cccaggatta tatagatatc tgagtcggtt aaatgagcag
     1741 ctactattcc tgcaccgaaa tacgtcaaca ccatggctac atagccagcc attgcatcta
     1801 ctacacttcc atccttcgag tattgctccc gatatctggc taagttccca tctactccat
     1861 ctagtaagtt ccataaaaaa aatagaaacc atgccagtaa taatacaacg aaatcagttg
     1921 taaatatcat tattataaat ccaacaatca aaggaattat agataaataa gatatttgat
     1981 tgggagtaat atttgttttc acgaaaggaa ctgttaaaag ataggataaa ggtcttccaa
     2041 cataaaatgc aaaatagtcg tttttagcca ttgctttttt agcaggcgac atagtttttc
     2101 tttcaatatc tttacaaagt ttatatattg acattatcat cctctcttaa actcatgaat
     2161 atattctcta actctgacac tttttctttt atttcaaatg tagatcgaac tctttggaaa
     2221 gcagcactac ctaactcatt ggctagttct ctattctcaa taatacttct acttctatct
     2281 acagttactt ctaaattata tagtgggact ttaaaacctg actcaccatc aataaccaat
     2341 tctgacatcc catcaacatt agttataaga attggcttct tatgtttcat atattccgca
     2401 accgccaatc caaagccctc ccatttcgag aaaagaactg cctgattgaa ctgagctaaa
     2461 taatcctctg gattatccac ccaccctgtt ataaaaaatg agcttcgaag cccatactct
     2521 tcaattagtt cttcagttcg cccacgcaat tcgccatcgc cgacaataac aaaatataaa
     2581 ttgctataaa tctctgataa tttttttgca aattcaacaa aaaagaaagg atttttctgt
     2641 tcactaatac gaccaatcat cccaataaca tatttattta tgggtaataa aacgtttatt
     2701 tgattttcgt taaaatcttc atcaatctct actccattat acactaaagt caatttctta
     2761 aggggtattt ttaaagattg agccgcttca tattcagatt tagagattaa tatatactta
     2821 tctgtaagat aagacaaaaa cttttcaata tttttataaa cgaattgctt aatcttagaa
     2881 acatccatct taaaagacca tccgtgagga ttgtatacta ctttacacga caaacccata
     2941 gaagctaacc tgcctactac acctgcaaaa gtactgtgca gatatactat atcaggtctt
     3001 tctagataca atatttttct aaattgttta atcgcgcgta aaagctttat tggagacaag
     3061 cttctataga tatcaatgtg ataaaacttt atattatatt cttgttcata tgtttgtcta
     3121 ttaagctgat ctgatcctac cacaatattt ttaaaatgtt ctttatctga atattttaaa
     3181 tataacttaa tatacctatc aactccaccg ccaacttcac taaaatgaag caatttcatg
     3241 aacatatccc cctatttggc tccatccttc atcaatacta ccttaactgt cttcaataaa
     3301 atttcaatat ctttccagat tgtccaatca tctatataag ccacatctaa tttgacaact
     3361 tcatcgaaat ttttgatttc acttcgtcca ctgacctgcc ataagcctgt tataccaggt
     3421 ttaaaactta gccgacgttt ttgttctggg gtatagtgtt catactcatc cactgttggt
     3481 ggccgtgtgc caaccaaact catatctccc tttagaacat tataaaactg tggtagctcg
     3541 tccaagctag tcttccgtat aaaacaacca attttcgtga tacgaggatc atcgtccacc
     3601 ttaaacattc caccctgcat ggtattttgt tccatgagtt ctcttttttt cgcctcggca
     3661 tctacacaca tagagcgaaa cttataaaaa gtgaactgac gaccattttt tcctatacgc
     3721 gtctgagcaa aaatagcaga gcccccatcc tttcgaatca aaggaaccag tacaatactg
     3781 actaaaccac ataatatcaa cccgaccaat gcacccacga tatcaataat ccgcttagca
     3841 attacatgac tagtcttata aaatgttgta gaaaaagtca caacgtttaa tcctgccatc
     3901 ttacgaattt gcttgttacg tgccaaacta cgatcaaaag catttagatt gactgttaca
     3961 tcaattccca tcgtttcaaa ctgagagaca agctctccaa tattgtattt ttcacttgga
     4021 agattgataa agacttcatc gaccacctca tgagtcgcaa agtttactat ctccccctct
     4081 gctactatct ttaaataatc atgctgaaaa tctggtttat ctaagacact gacggctacc
     4141 aactccccaa caacctcatt tgattctatt aatccatcca gtaccttttc gacacgagaa
     4201 gttgctgtaa gtaggagaat cttcttactt cctttaaagt tgggataagc ccgcttccaa
     4261 taccacttga taaataggtt tagcacatag actaagagag catgtaatgt gaggaagtaa
     4321 atcatgcctc gtctggaaat actaaatcga tcctctaaga aaaaattaga aatactaatc
     4381 gctagtgcaa agaataggat atatttcaat gtctggacaa gttcaatcaa atatcccctt
     4441 ttaaagaaat cctgtccata atcactgata taaaagacaa aataatggag gatataaagt
     4501 gcaatagctg ttgttgaaac aatcttcgct tctctcacag tactaagtag ataagtcaat
     4561 aaaataacaa gagaactctg gattatgacc aatgaagact ttactatttt tccattcatc
     4621 tctatccccc gacctatttt ttatttttcc cgtaatttcc ataatttcca taagaaccgt
     4681 atttgtctat tgaagtatcg aatttattca acacaactcc caaaaacggc ttccctgtgt
     4741 gttccaactg ttcttttgct ttttgaatat cccgtcgatt tatttcacct gcctccgtca
     4801 ctaaaataga agcatcgcat tttcgcgtaa taatagccgc atcaatcacg acaccgacag
     4861 gagcagtatc tacaatgatg tagtcaaaat atttacgcaa ggtttcaagc attgtagtga
     4921 aattcttact ttgaagaaga gctgtcggat tcggtgacac agagccagcc tgaattacaa
     4981 agagattttc gatattggta tcacaaagcc cttgtgatag gtctgtagtt cctgataaaa
     5041 attctgtcag gcctgtaatc ttatcccttg ctttaaagac acctaacata acagaattgc
     5101 gaatatctcc atcaatcagt agcgttttgt atcctgcacg cgcaaaagcc caagcgatat
     5161 tggtggaagt cgttgatttt ccttctccta gtttcacaga agtgatagaa aatactttca
     5221 aaccatctcc acttaactgt aggttcgtgc acaaagcgtt ataatattcc tctgcctttt
     5281 ttacagaatc caattttgcc tgtgagattt ctaatgttgg cataacttcc tcctatttca
     5341 ttttgtcaaa atctggaacg agccctaaaa gtggaatttt cagtacatct tcaacatctt
     5401 caggacgttt cacacgggtg tcgagcaact caatcaaaag aacagcaatt actgttacga
     5461 ctgctcctcc aagaaaacca aacaaggaat tgcgtcgaac atttggagaa gagggagttg
     5521 tagctggtcg cgcttcttca agtgtcgtta catcagatac tcgcgttaca gcgacgatct
     5581 tttctgcagc aacttctcgt agagaattag cgatacgact ggcttcctct ggctgtttat
     5641 ccttgacaga gattgagacg atacgagtgt cagctggtac agccacttga actttgctgg
     5701 ctaacgtttt tgctggcata tccaacttca aatttgtcgc tactttttcc aatgcatcct
     5761 gcgaaaggat aatctcacgg tagtctttca ccagataagt tcctgcctgc aaatcctgat
     5821 ttgtcagccc cggcttgtct ccttgattgc gattcactac gtaaattcgc gtggtactcg
     5881 tatattctgg cttaacaata aaagtgctat atgcaaaagc ccccgcactt gtcacaagtg
     5941 ccactaataa aatcattagc ttgcgttgcc acaaggtttt aaataattga aatacatcga
     6001 tttctatcgt gttttgttct ttcatcattt ctcctaaatt agttgatcca ttacaatttt
     6061 tcgaggattg tctataaaaa gttcctgagc cttcgcttct ccgtattttt gggtaacaag
     6121 gtcatatgct tctgccatat gaggaggtct accgtctaga ttgtgcatat cacttgcaat
     6181 gacatggacc aaatcctgct ctaaaaaata ctgagctctt tttttcatga atttataacg
     6241 ttcgccaaaa agtttgggtt tgaggacatg tgaactattt acttgcgtgt aacagcccat
     6301 atcgattagt tctcgaacgc gtttttcatt attttcaaga gcatcatagc gctcaatgtg
     6361 ggcaatgact ggagtaattc ccaacatcaa gatcttgctc aaggcgctat gaatatcgcg
     6421 ataaggagtg ttcatactaa actctatcaa ggcataacga ctatcattga gggtcggaat
     6481 ccgctttttt cccagcttat ccagaacatc tggtgtgtag taaatttcag ccccgtaagc
     6541 aatgactaag tcactcgcca cttccttagc tatttcccga acctgaagaa agttttctgc
     6601 tatcttctct tccggagttt caaacatgcc cttgcgacgg tgagaggtag agacaatggt
     6661 tcgcaccccc tgtctgtagg cttctgccaa gagagccttg ctttcctctc ttgacttggg
     6721 accgtcatct acatcaaaaa cgatatgcga atggatgtct atcatttcat ctaccctcca
     6781 tcacatcctg tatagctgct ttaactacag ctaaactact atcatctatt tccatcacat
     6841 agaggttact gtctggcatt gcataagaag gaagatccat ccgacctgtc ccttttaaat
     6901 cttgagaatt tactttataa tcccccccac tttccaactg agtattcact aaatctatca
     6961 tagtctcaat cggcatattt gtttgaagag aatcctgcaa tccttgaaga atactactat
     7021 agtttttcaa aacctctgta gaagttaact tcttaataat tgctacaatg accttttgtt
     7081 ggttgcgacc acggtcacga tcgccatctg ctagtgagta gcgctcacga acaaaaccga
     7141 gagcctgttc tgaatcaaga tgaacattgc ctacagggta atactttcca ttcgtatggg
     7201 cagtaaattc ttgatcatta taaacatcaa ttccacccaa caaatcaatc aatttcaaaa
     7261 acgaagtgaa gttcaatcgc acatagtaat tgatatccac tccatagaga ttttctaagg
     7321 tgtgaatgga cgaatcaact ccataaatgc ccgcatgggt taatttatct ttttgattat
     7381 ttccaccatc tgcgattggt acataggcat cacgtggtgt tgtggtcaag aggattttct
     7441 tggtatctcg attgacagtc atcaggatat tgacatctga tcgcgacacc gaactaatag
     7501 gaccataggt gtcaattcca ctaacataga tattgaaaga ctgattctta gacgtcttag
     7561 gagcttctac ttttttagtg aatcccttgg tataaatctt ttttatcttc gatgcatagt
     7621 ctggatactc tgactcgatg atattttcaa agacactatt taagacaatg gccttagtct
     7681 cccctgcaat caaactcttg taagctgcca agtaagacga actctggtcg accgtcaaat
     7741 cggtattctg acttgacttg atatcagcta gtagtttttg aatattttca ttatcagtcc
     7801 cagtcggtgc tgtcacactc gtcagttgcg taacattttc gatctcacta tctgctaaaa
     7861 cagcgacact gattgaatat tctgagtaat tagaagtcgc atttaaacga ttggtcagtc
     7921 caacaaactg ctgtactgca aagagcgaca ctgagctgac aaggatagaa aacaccaaca
     7981 gaaaaatagt aaatttttca gcttttttat agataatcaa gagtagccct accaaggcaa
     8041 ctagtaggac taacgcagtt accactagat taagatatct aaaagcaagg atattgtact
     8101 taaagattaa gaacaataaa aaacaaacta acaataaata aatagtcaac aaaactatat
     8161 taacacttcg cttcactttc tgtgaacctg attttttaaa acgtctactc atgattaaca
     8221 cctatacatt gaacatcata cgattatatc acttttttac ggtaatgtct acaccttttt
     8281 tcactatctg catctttaag tatcttagta gacttcccac gaaccaaaaa tatagtaaaa
     8341 tgaaataaga acatgacaaa acgatcagga cagtcaaatc gatttctaac aatgttttag
     8401 aagcagaggt gtactattct aatttcaatc taatatagta cacaatgtgg tataatctt
//
LOCUS       DAVLZS010000067         8386 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLZS010000067 DAVLZS010000000
VERSION     DAVLZS010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.067"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            16..507
                     /gene="tpx"
                     /locus_tag="VYO88_001837"
     CDS             16..507
                     /gene="tpx"
                     /locus_tag="VYO88_001837"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1719881.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(603..3311)
                     /locus_tag="VYO88_001838"
     CDS             complement(603..3311)
                     /locus_tag="VYO88_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1719882.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLININVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(3313..4014)
                     /locus_tag="VYO88_001839"
     CDS             complement(3313..4014)
                     /locus_tag="VYO88_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719883.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            complement(4264..6675)
                     /locus_tag="VYO88_001840"
     CDS             complement(4264..6675)
                     /locus_tag="VYO88_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1719884.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLTKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGVSYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLTNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            complement(6728..7420)
                     /locus_tag="VYO88_001841"
     CDS             complement(6728..7420)
                     /locus_tag="VYO88_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1719885.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            complement(7954..8334)
                     /locus_tag="VYO88_001842"
     CDS             complement(7954..8334)
                     /locus_tag="VYO88_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719886.1"
                     /translation="MKLKRLALISGIVGLVGGILLLIGPFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
BASE COUNT         2399 a         1964 c         1556 g         2467 t
ORIGIN      
        1 agattggagt atcctatggt aacttttctc ggaaatcctg tgagctttac aggtaaacaa
       61 ctacaagtcg gcgacaaggc gcttgatttt tctcttacta caacagatct ttctaaaaaa
      121 tctctggctg attttgatgg caagaaaaaa gtcttgagtg tcgttccttc tatcgataca
      181 ggcatctgct caactcaaac acgtcgtttt aatgaagaat tggctggact ggacaacacg
      241 gtcgtattga ctgtttcaat ggacctacct tttgctcaaa aacgttggtg cggtgctgaa
      301 ggccttgaca atgccattat gctttcagac tactttgacc attctttcgg gcgcgattat
      361 gccctcttga tcaacgaatg gcacctatta gcacgcgcag tctttgtcct cgatactgac
      421 aatacgattc gctacgttga atacgtggat aatatcaatt ctgagccaaa cttcgaagcc
      481 gcaattgcag ctgctaaagc cctatagaaa aaatcctctg tcacaaagag ttccctgctc
      541 tttgaaacgg aggatttttg aatattagta aatagaagtt caatcagcta aaaataacta
      601 ccttactcta cagatttcag ggcttctaac atatcaacct ttctcagata ataattgacg
      661 aagaaaccaa gcaaggtcaa aatgatgctt actgctgcca ctgggattac atagacttcc
      721 cagcctacct gcggataaaa gagaatagtc gcaggcgaaa tcatttgaat caaaaattgg
      781 tgtaaataga aaccagctac cagaccaagt acgattccca caagggacag cacaatcgtc
      841 tcacggtaaa tgtagagtgt gacttcatta ttatgaaaac cgagaacctt gatagtggag
      901 agttcacgga ttctctcagc tacgttgata ttgatcagat tgtaaaggat gacaatagct
      961 aatagaaccg acacgatgac taaaatggtc atggtctgat tgagtgagct agcgatagag
     1021 tcgaagagtc gaatggctga agcattttgg acaacgctgg acaccgcaga ttgattcata
     1081 agcaagcccg cctgactttc gatactagtt gcactggtat cccttaatga gaccagataa
     1141 gtgttggctt ggggtagctg tccgtaaagt tgctcatagc tagcctgact catataaata
     1201 aagtgaccaa cgtagttctc agtaatagca gcgaccttta gttccttacc ttcaatttct
     1261 aaagtctgcc caaccttgac acctgccagc tgggcgagtt tagctgtaat aacgatgcca
     1321 tcttttaatg tcagctcctg ctgatgatgt tgaagatgga taaagggagt caaatcttcc
     1381 ttctctatca tcataagagt aatgttttga agaccagcct tgcctttgaa atccttgtct
     1441 agcgttttag aatagatttt ctggtaggct agtatctcct gccctttcaa cacttctgct
     1501 agctctacct tgtcctgatt ggtcgcacta ggattttcag agacaagcat ctgatactgt
     1561 tggatttgtt gaaactgttt agacggaact cctgctacag aagattggat tcccaaacct
     1621 gcaaagagca gagctacaga acctgccaca ccaaagattg tcatcaacat tctctgctta
     1681 taacgaaaga tgttgcgggc tgttacctta tgagtaaaac tgagacgacg ccagataaaa
     1741 ccgatacgct ccaataagat tttagctcct ttgacaggag gtttaggaag tagaagctgg
     1801 gctgcttcgg catgaagttc cctccaagcc accagatagg ctggtaacac actcgccaac
     1861 cagctcaaga caagagctag taagctatag gtccaataga actgaatctg ggtttctccc
     1921 accaccatgc cttttgtaat gacacttgaa attacactgg ctagcaaata atgaccaagt
     1981 atactaccta gagccgttcc gacagtccca gctactagtc cataaaggag aaacttggcg
     2041 ataatatcct tactacggta acccaaggcc ttaaaaatcc ctgcatgagt tcgctcttcg
     2101 tctacaaagc gagtcatggt cgtaaaggtc accatggctg ctacggcata aagtaccaca
     2161 ggaaagatat tgcccactgc tcgaatactg gatgaagcat tgctatacat aagatagccc
     2221 tgaccacctg gcatggtctg acgattatag acctgatacc ttggctccgc caaatcgtcc
     2281 aagacttgct gatgtttttc taatttttcc ttttcttggg ctagattttg ttcagcttgc
     2341 tttagtttat cctcttcctt gcccaattcc tgcttggctt gggtaagttg agcactagcc
     2401 tgctctctct gaacttgagg aaacaaggct agttgacttt cttgagcctg tatacgagct
     2461 tgagcagctg ctaaacgacg cttgccttcc tgcaaattag tctgagcctt gtcaagggtc
     2521 tcttgcccct tgtctagaga ctcttgtcct tcttttttca aaagttgcag acgtaccttg
     2581 ccattatctg ataaagtttg ttcaaggtct tcctgatgtt gcttggattt ttcttcataa
     2641 gctgatgaaa aggcatttaa acctgctaaa tcttgatatt tcaaacgagc tatattgtag
     2701 actttctgat caaactgact aggtaaaatc accccatagg ctgtcagagt cccacttcca
     2761 cttcctgcgt agcccatatc tcgctgggag aggatttcag ccgaatccac aaaaccagta
     2821 atggtataag tatggtcttt taaagaggaa tgaccctctt ctttttcttt aaaactaatc
     2881 tcctgtccca cgctgtattg gccttgcaaa tgagtggcca aagcgatttc cttgtctgac
     2941 tgaggaagtc gtccctttct tagctgaaag gttgaaattc gctctggttt ggagtacagc
     3001 cgaatggcat cctgcccatt atccatagtc acatctgtca aatagccaaa ctcgacctct
     3061 gcgccctccg tctgttttag ttcttcttgg tctgcttgat ccaagccata gttagacatg
     3121 actgccaaat ccaaggtttg agcagttgtt aaataagcat tagctgtcgc ctccatgttg
     3181 ggactggtta ctttgaggcc tactaaggct agagatccca acatcatcag gatcaagatg
     3241 gataaaaaac gccccttgga gcctgtgaag gactgaatta agtccttcca ataagttttt
     3301 cgcttgatca tactagtact ccaaactgtc aatatcctga ggatgctggt tgagcaccac
     3361 atccttgaca ctggcatcgt gcatatgaat cacgcgatca gcaatgggcg ccaaagctcc
     3421 attatgagtc acgatgatca ccgtcgctcc cttttgacga gacatatctt ggagaatttt
     3481 caaaacctgc ttgcccgtct gataatccaa ggctccagtc ggttcatcac aaaggagaat
     3541 tttaggattt ttggctaccg cgcgtgcaat ggagactcgc tgttgctccc ctccagaaag
     3601 ctgggctgga aagttattga gacgatgagc cagacctaca tctgtcaaga cctgatcagg
     3661 attcaaggca tctgtcacaa tttcagaagc cagttccaca ttttccttag ctgtcagatt
     3721 agaaactaga ttataaaact gaaaaacaaa ccccacatca tttctacggt aattggtgcg
     3781 ctggtgggaa ctataatccg caatattaac accatcaatc cagatttccc cttcatcatt
     3841 ggtatccatt cccccaagaa ggttaagaac tgttgacttg cctgcacctg aagcaccaag
     3901 gataataacc agctccccct tttcaatctc aaaattcaca tcacgattgg ccacaatctc
     3961 cgtgtcccca acctgataac gcttgtaaca gtgtttcatc tcaatataag ccatcagacc
     4021 caccctctat caaacaaatt atactcctcg aaaatctctc ttcaaaccac gtcagcttcc
     4081 atctgcaacc tcaaaacact gttttgagca acctgcggct agcttcctag tttgtgctct
     4141 ttgattttca ttgagtatta cttcctatta tcattataac gctttttcaa ctagttgaaa
     4201 actgcttata ttcttaaatc cttattaaaa ggcagtttca aattactgcc ttataacatc
     4261 ttcttaaaaa taaaattgaa caagatcacc ttctgctgtt gccaccgaaa tacaatcttt
     4321 ccccatgcat ttcgctttta ttttttcttg attcatttta atcacactct tctcaatatc
     4381 tggataagaa actcgcaaat ctcctccact ccttgataaa atggtcaact gtaagagttt
     4441 tttatcttcc cagctcatgc tcacttcaaa atgtccacgt gccattaagc ctgaaacaga
     4501 accggttgac caagcatcag gtagggcagc tagaggtacc agataagctg catgagactg
     4561 gagtaacatt tctgccatgc cactagtagc accaaaatta ccatctatct gaaaaggagg
     4621 atggctacac caaagatttg tcaaggtgga tgtctttaac tgctctgcca ataatttatg
     4681 ggctcgattg ccatctccca aacgcgccca gagattgatc ttattagcct tggaccagcc
     4741 tgtgccgcca tctccacgat cattgaggct agcacgtgcc gcttcaatat actcttgtcc
     4801 cttgtagcta aagagattgc caggatagag tcccactaga tgggaagcgt gccggtgctg
     4861 ggcctccact ttctcatttt gaaaatactg ctcttcctcc tcataccact ccctgattcg
     4921 accagattga gtgatttgca aaggatttag taaatcagac ttctccttaa cctcagtcaa
     4981 caagtcctca tccagtccca attcctgagc agcctgaata aaatcatgaa ataactgcca
     5041 aatcagagat tggtcataag tattgccaat cgaaatcggc ccatgttctg gggaataaga
     5101 cggagaagac acccaacgct gcgcctgctg atccttatgt aaaaaggcat tccaaaaacg
     5161 aaccgtttcc ctcaacatgg gataaatttt ctctctgaga tagtcttggt ccctataaaa
     5221 tgaataggct tcataaacgg tttgcatcat ccacgcattg gcagctggtg accaacccca
     5281 atagtaatcc caaccaggtg ccgtccaacc aaagggagtc gcttgagtat gaaccaacca
     5341 accattctcc tcacctttct gagagacgat tcctgcatac tttacagccg ctagacgacc
     5401 atagacacgc aaatcatcta catagttgat gactggaaag accgtctcta ggagattggt
     5461 aacataggct ggccaataat tcatctgcag attgacattt aagtgatagt ccgaattcca
     5521 aggaggattg tcgaccgcat tccagactcc ctgtaggtta gctggtagag catctgggca
     5581 gtctctggac gaactaatca ataaataccg tccatactgg aagaacagct cctccaaagc
     5641 ctgcccttct tgtggcttat aattttttaa caaatcatct gtagtggatg cgtcaacatc
     5701 agcttccaaa tccaattgaa cacgctggaa taaggcttgg tagtcctcga tatgccttga
     5761 tttcaattgg gtatagccct tttctttagc tgtgtccacc aagtctatca cctgttgctc
     5821 taaatctagt ttcttgcgat aattgctagc aggattttgg gcaaaatccg tcttagcggc
     5881 caagaagaga ttggcataac tgactcctga tatctgaacc ctatctgacc aaactctaat
     5941 atctccatcc gtttcccaag ctagataact agcaaaccgc agatcattat ccttaactct
     6001 tcccttcatc aagatatgag aatcagtaat atccaactta cactccttgt aatcagattt
     6061 ttcctgctca tactttccat cagaagccaa atcacaggtc aaggatagtt ctatagtaaa
     6121 atctagagtt tccaaccctt ccttagtaaa acattgaatc aagagatcat ctggaaaact
     6181 cgcaaaagct ttacgttcaa atcgcgttcc cttatagaca taagaagtcg tcgcaagtgc
     6241 cttactaata ttcagctgtc tctgatagtc cgtcacctga gacaaagtcg taccttgctg
     6301 gctgaactca atgtgaatat ccccaaaaga cagataggtc ccatattgac tcgtttttgg
     6361 cccaattagg tgctgctcag ccagttcctt agtcagattg taatctctct tctccaaagc
     6421 ctgccgaatc tcagctaaaa aaacatactg atcctgaaga tttccaccct gataatctga
     6481 actatcagga agtggacctc cagaccagag acttttttca ttaaattgaa tccgttcagc
     6541 ccctataagg ccaaatactt ttgctcctaa agaaccattg cctatcggta aagcttcttc
     6601 ttcccaaccc atgtaagtgg ttgaagctgg ttgcttgtag gccagtacat aatcttgttt
     6661 tttattcctt atcatacttc catactaaca taaaaagcct agaaatcaat cctaggctta
     6721 caatttttta ttttccaagg tagtattcag aaacaacgtt caatttttcg tcgaattcga
     6781 ataccaatgg tgggaagtta gggatttcca cgtccatgat ctcatcatct gacaaacctt
     6841 tgatgtgttt tacaagggca cggattgagt taccgtgagc tcctacgaat acgtttttac
     6901 catctttaag agctggagcg attttatctt cccagaatgg aagagcacgt tccaaagtca
     6961 ctttcaagtt ttcagcatct ggaatgactg agtcgtcaag tgaagcataa cgacggtctg
     7021 tgtgagctga gtgctcatca tcacggtcca tatttggagg caatacatcg tatgaacgac
     7081 gccagatgtg aacttgctca tcaccaaatt gttcagcagc ttcagctttg tttttaccag
     7141 tcaaaccacc gtagtgacgt tcgttcaagc gccatgattt ttcaactgga acccacaatt
     7201 ggtcagaagc ttcaagagcc aagttagttg ttttgatagc acgtttcaat actgaagtgt
     7261 aagcttggtc aaattcgata ccagcttctt tgatcaattt accagcgtca atcgcttgtt
     7321 gtgtaccttt ttcagacaaa tcaacatcag cccaaccagt gaaaaggtta gctttgttcc
     7381 attcagactc accgtggcga gcaaaaacca attttaccat tagatggatt ctcctttaaa
     7441 ttttccgagg tttcccctcg tttatctatt ctattttaca caatttttca caaaaaagct
     7501 agtcaaaacc aaaaaggaaa ggactgtttg acaatgtttg gcaatcacat tgtttttggt
     7561 tgtttctatt ctatcttcat tatttaacct ttttttctgc gcatcgaata atttttgagt
     7621 tgactctttt agtttagtaa acgagtcatt attttccata gttgtgcctt tgaaaccttc
     7681 ctcagcttta gtaaaataat catcaaaaat atttttataa agatctatat aatctgcata
     7741 agtgcgtatt gattcaatcg catcgtctgt tacaaccggt gtatcgaaag tgattgtttc
     7801 ttttgaacta ttggatgttg ctactgtctt ctcatcatta cttgttgaag tattctttga
     7861 actttatgtt ccacatgcaa ctagaagaga aagagataat agagctactc ctataccgat
     7921 aaactttttg ttcttttcat gctaaaatac cttttattct tctgatttga atttcttcaa
     7981 tgttgcaagg aatagagatc ctccgataat agcaagaatc cccccaaccc atcctaagaa
     8041 tggaatgaga ctaactccac cagaaacaat cattagtaca gacggagctg cacctacacg
     8101 cttatctcct ttatagtaaa caatagcaat gataccaaga acaagatttg caatcttcaa
     8161 ggcattcaag agtaaggcta cacctgaaaa agcccctgca gtagctcctc cattaagagt
     8221 tgtagcagct gtgtttaccg ctgttcccaa caagacaaaa ggaccaataa gaagtaaaat
     8281 tcctcccaca agaccgacga taccactaat taaagcaagt ctttttaatt ttataataaa
     8341 atctcctttt ttattttttt caaataaaat tgtatcatat ttgctt
//
LOCUS       DAVLZS010000068         7193 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLZS010000068 DAVLZS010000000
VERSION     DAVLZS010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.068"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..900)
                     /gene="phtA"
                     /locus_tag="VYO88_001843"
     CDS             complement(<1..900)
                     /gene="phtA"
                     /locus_tag="VYO88_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV1719887.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAKAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLS"
     gene            complement(1154..2887)
                     /gene="ptsP"
                     /locus_tag="VYO88_001844"
     CDS             complement(1154..2887)
                     /gene="ptsP"
                     /locus_tag="VYO88_001844"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1719888.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(2893..3156)
                     /locus_tag="VYO88_001845"
     CDS             complement(2893..3156)
                     /locus_tag="VYO88_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1719889.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            3507..3725
                     /gene="nrdH"
                     /locus_tag="VYO88_001846"
     CDS             3507..3725
                     /gene="nrdH"
                     /locus_tag="VYO88_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1719890.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            3806..5965
                     /gene="nrdE"
                     /locus_tag="VYO88_001847"
     CDS             3806..5965
                     /gene="nrdE"
                     /locus_tag="VYO88_001847"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1719891.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGECYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            6153..7115
                     /gene="nrdF"
                     /locus_tag="VYO88_001848"
     CDS             6153..7115
                     /gene="nrdF"
                     /locus_tag="VYO88_001848"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1719892.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
BASE COUNT         2082 a         1549 c         1344 g         2218 t
ORIGIN      
        1 actcaaaggc agtttgtaga gctgtttcaa gagactatca atgtcattac tttgacttgc
       61 ttgactgtta gtgttgctgt tgttgcttgt gttagtattt gtagttcctg gattgcttac
      121 agaaggtacc cagtttgttc ttgaagtgtt atcgctattt tgtcggcgat aggttcttga
      181 atttgacaga tttccccgac cagataggaa ggcttttgca gcagctaact cgctagctga
      241 taactcattc ttaggaatgt aatggtaatg gtcgccgtga ggaacgatat aagcatcacc
      301 agtatcctct atgatatcag aagcattaaa gatataacca tcatctgtag tatagcgtcc
      361 ttgcgaacgt gccaaggcaa cagcaccatc gtttcttgga gtcccacctt cacgatgttg
      421 actatgttct tgtttttgcc gattgatttc ctcttttgta cggacgttat ccgcgtgggc
      481 agcatcctta aggtaaacat agtattttcc atctaccttg ataacatatc cacccttgac
      541 ctcattaaca atatcctcat cttttagctt atagtttgga tctttcatga gtaattcttc
      601 actgaaaatc gcatcataag gaaccttacc attgtaataa tgatagtggt cgccatgtga
      661 agtgacatag ccttggtctg ttatcttgat gacgatttgc tcagcattga ttccttcacg
      721 cttgctaacc tcatcaggag tcaaattctc cgttttttgc gtcgcttgtt ttccatctat
      781 ataggaaaca cgattatttt ccttaaccgt tctagcttga tacagtccca actcgtaaga
      841 acaaacactt aaaatcaaag ctgccgcaga accaacaagg tatttcttat taattttcat
      901 cgaaactctc tttctatttg atatttctag ttgcaattca tttctaaatt gcagaaactc
      961 ctctctatta cttaactggt taatagttta ctcctaaatc tccaacttgt caagaatttt
     1021 atgaaccatt taagtatttt ttgttctgac tactactttt tcaaggttgg actttctata
     1081 agaaagattt tcttgaaaat tctttttaaa atatcaaaaa aatccctgta actgagttgc
     1141 agggactttt cgattaatca aaattaacgt attctttttg aagttcaaga acttcttcca
     1201 ttgttgagca ttctgtaagg gcacggtttg cgtactcttc catcttagct gtgtcgagtt
     1261 tcttcatcaa gctgcgtgta cgaagtacag acgttgctga catagagaac tcatccaagc
     1321 ccattccgac aagaagtgga acagcttgtt ggtcaccagc catctcacca cacataccag
     1381 cccatttacc ttcagcgtga gctgctttga tcacattgtt aatcaagcgt aggattgatg
     1441 ggttgtatgg ttggtaaagg tatgaaactt gttcgttcat acggtctgct gccattgtat
     1501 attggatcaa gtcgtttgta ccaattgaga agaagtcaac ttctttagca aattggtctg
     1561 caagcatagc cgctgcagga atctcgatca tgataccaac ttggatgtta tccgcaactg
     1621 caacaccttc agcaagaagg tttgcttttt cttcatcaaa gactgctttc gctgcacgga
     1681 attctttcaa gagcgcaacc attgggaaca tgatacgcaa ttgaccgtga acagacgcac
     1741 gaagaagagc acggatttgt gtgcggaaca tagcatctcc agtctcagag atagagatac
     1801 gaagagcacg gaatccaagg aatgggttca tttcgtgagg catatcgaag taaggaagtt
     1861 ccttatctcc accgatatcc attgtacgaa cgacaacagg tttaccgttc attccttcaa
     1921 gaacagcctt gtatgcttca tactgctcat cttcagttgg gaagtcttga gaatccatgt
     1981 acaagaactc tgtacggtaa agtccaacag cttctgcacc gttgttgtta acaccttcaa
     2041 cgtcttttgg agtaccaata ttggcagcca actcgaagtg tttaccgtca gcagtcactg
     2101 tttgagcatc tttcaaaagt gcccattcag ctttttgttt cgcataggct tcaccagctg
     2161 ctttaaattc tgccgcttgt tcatctgttg ggttgataat cacttctcca gtgatcccgt
     2221 taacagcaag gatgtcaccg tctttaacga tttcagtgat gttgtttgta cctaatacag
     2281 cagcaatttc aagtgtacgt gccatgatag ctgagtggct tgtacgtcca ccaatgttgg
     2341 ttacaaaagc ttttacaaag tttttgtcca attgagctgt atctgaagga gtcaagtcat
     2401 gcgcaatcac aatcacttct tcattgatag aagctgggtt tggcaatttt ttaccaagaa
     2461 ggtttgccaa tacacgtttt gtcacgtcgc ggatatccgc tgcgcgttct tgcatgtatg
     2521 ggttgtcttc catgccttca aagatagtga taaacatatc tgtaacttct ttcagacctg
     2581 cttctgcatt cactttcttc gcacggatag tttccttgat ttggctgatc atttctgggt
     2641 cagcaagaac cattaagtga gcatcaaaaa cttgagctgc ttcttcaccg agcgtaccta
     2701 ctgctttctc gcgaataaca gaaagctcgt cttgtgatgc ctgtagagcg gcatcaaggc
     2761 gagcttcttc tgcgtttgta tcttcgactg taatagtctc aaatgacaaa tccggctgaa
     2821 cgagtagata tgcttttgca actgcaacac cgtcagatgc tgcgattcct ttaagcattt
     2881 ctgtcatttc ccttatgcca atccttcttt ttccattgtt tctgagattg cagcgatagc
     2941 gtcatctgca tctgcacctt cagctgagat agttacgtca gcaccttggc caacaccaag
     3001 actcataaca cccataattg atttaaggtt aactgattta cctttgtact caagagtgat
     3061 atctgaagca aatttgctag cagtttgtac caacaatgtt gctggacgtg cgtgaatacc
     3121 tgtttctgcc actacgtgga aatctttaga agccatagtt tgactctcct tttgttcttt
     3181 ctttttttga gttatatgtg ataaccctta caatttagta ttataccatc ttctaggatt
     3241 tttttcaagc attttctgga ttttccttca atttcctttc agataacttg ctgaaaatct
     3301 tctatcctag ataacaaaac acaggatata gtttctttaa aaacaattta taggataatc
     3361 attgctattt cacaatacaa acactatata ttgtgtttat atataaaaac aacaaaagaa
     3421 caccactata tttagttcaa atcattgaca aaattttatt ttctgatata ctaagatagt
     3481 attaaatttt gaagaggagt tacacaatgg taaccgttta ttctaaaaac aattgtgtcc
     3541 aatgtaaaat gaccaagcgt ttcttggaca gtaataatgt ctcttatcgt gaaatcaatc
     3601 ttgatgagca acctgagtac gtcgatcaag ttaaagagct cggttttagc gcagctcctg
     3661 ttatccaaac accaactgaa gtcttttcag gtttccaacc aggaaaactg aaacaattag
     3721 cataatctta gtacatcatc cagaagaaac tacttttagg gctaacttag aagcctttct
     3781 tttgtaatta gataagggaa attttatggg attaaaacat cttgaagacg tgacttactt
     3841 ccgtcttaat aacgaaatta accgtcctgt taatggacaa atcatgcttc ataaagataa
     3901 ggaagccttg gatgctttct ttaaagaaaa tgtagttcca aacactatgg tttttgattc
     3961 aatcaaagac aaaatcaatt acctcattga acacaactac atcgaaacag cctttatcaa
     4021 gaaataccgt ccagagttct tggaagaatt ggctcaattt atcaaagacc aaaacttcca
     4081 attcaagtca ttcatggcag cttataaatt ttacaatcaa tatgccttaa agactaatga
     4141 cggtgaatgc tatcttgaaa atatggaaga ccgtgtcttc ttcaacgccc tttatttcgc
     4201 tgatgggaat gaagctgttg caatcgatat tgccaatgaa atcatccacc aacgctacca
     4261 acctgctact ccttccttct tgaatgctgg acgtgctcgt cgtggggagt tggtatcttg
     4321 tttcctaatc caagtgacgg atgatatgaa ctctatcggg cgttctatca actcagctct
     4381 tcaactttca cgtattggtg gtggtgtggg aattaccctc agcaaccttc gtgaagctgg
     4441 tgcacctatc aaaggctatg aaggagctgc ttcaggtgtc gttcctgtta tgaagctttt
     4501 tgaagacagc ttctcttact ccaaccaatt ggggcaacgt caaggtgctg gtgttgtcta
     4561 cctcaacgtc tttcacccag atatcatcgc tttcctttca actaagaaag aaaacgctga
     4621 tgaaaaagta cgtgtcaaga ctctatcact tggtgttgta gtacctgata aattctacga
     4681 attggctcgt aaaaatgaag aaatgtacct cttcagccct tactctgtag aaaaagaata
     4741 cggtgtgcca ttcaattaca tcgacattac tgaaaaatac gatgaattgg tcgcaaatcc
     4801 aaatattcgc aagacaaaaa tcaaggcgcg ggatttggaa actgaaatct ctaaattgca
     4861 acaagagtct ggctatcctt atgtagtcaa catcgatacg gctaaccgtg caaatcctgt
     4921 tgatggaaag attatcatga gtaacttgtg ttctgagatt cttcaagttc aagaaccaag
     4981 cttgatcaac gatgctcaag aattccttca aatgggaaca gatgtttcat gtaacctggg
     5041 ttcaaccaac gtggttaaca tgatgacttc acctgatttt ggtcgttcta tccgtgctat
     5101 ggttcgtgcc cttactttcg ttacagatag ttcacatatc gtagctgtac caacgattga
     5161 ccatggaaat agccaagccc acacctttgg tctcggtgcc atgggactgc acagctacct
     5221 tgcccaacaa ctcattgaat atggttcacc tgagtctgtt gaatttacaa gcatctactt
     5281 tatgcttatg aactactgga ccttggtaga gtcaaacaat attgcacgtg aacgtggtat
     5341 taccttccac aactttgaaa aatcagacta tgctaacgga agttactttg acaagtatgt
     5401 aactggtgaa tttgttccaa catcagaccg tgttaaagaa ctcttcaaaa atgtctttat
     5461 ccctggtgtt gctgattggg ctgaacttcg cgacaaggtt caagaagatg gtctttacca
     5521 ccaaaatcgc cttgctgtag cgccaaatgg ttctatcagc tatatcaacg acgtttctgc
     5581 ttctatccac ccgattacgc aacgtatcga agaacgccaa gagaagaaaa ttggtaaaat
     5641 ctactaccct gctgctggct tgtctacaga aaccattcct tactacactt ctgcctacga
     5701 tatggatatg cgtaaagtca tcgatgttta cgctgctgcg actgaacacg tggatcaagg
     5761 actttcactc accctcttca tgcgcagtga cattccaaaa ggcctttacg aatggaagag
     5821 ggaaaataaa caaacgacac gtgacttgtc catccttcgt aactatgcct ttaacaaggg
     5881 aatcaagtct atctactacg tccgtacctt tacagatgac ggtggagaag tcggcgccaa
     5941 ccaatgtgaa agctgtgtga tttagtttct agcatagaaa cactattttt ccctaagcag
     6001 cactgataaa atcaaatcta ctatgtcata acataattta tgtaacattt taaaagtcgg
     6061 gcttccgact ttttgtgcga tactcctata gaattatggt aaagtagaaa taattgtgag
     6121 ttcgcaatac taaacacaga aagagatttt aaatggaaac ttactacaaa gccattaact
     6181 ggaatgccat cgaagatgtc atcgacaaat caacttggga aaaactgacg gagcaatttt
     6241 ggctcgatac acgtattccc ttatcaaacg acttggatga ctggagaaag ctatctaaca
     6301 aagagaaaga cttggtcgga aaagtttttg gtggtttaac ccttcttgac actatgcaat
     6361 ctgaaactgg ggttcaagcc cttcgcgcag acatccgtac accacatgag gaagctgtct
     6421 tcaataacat ccaatttatg gaatctgtcc acgctaaatc ttactcatca atcttttcta
     6481 ccttgaatac taaggctgag attgaagaaa ttttcgaatg gaccaatacc aatccttacc
     6541 tacaaaagaa ggctgagatt gtcaacgaaa tctacctaaa cggcagccca cttgaaaaga
     6601 aagttgccag cgtcttcctc gaaaccttcc tcttctactc tggtttcttc actcccctct
     6661 actatctcgg taacaacaaa cttgccaacg ttgcagaaat cattaaattg attattcgtg
     6721 acgagtctgt tcacggaacc tacattggtt acaaattcca acttggtttc aatgaattac
     6781 ctgaagaaga gcaagaaaaa ctcaaagaat ggatgtacga cctactctat actctttatg
     6841 aaaatgaaga aggctacaca gagagtcttt atgacggtgt tggttggact gaagaggtta
     6901 aaaccttcct tcgctacaat gccaataaag ctctcatgaa catgggacaa gatccacttt
     6961 tcccagattc agctgaagat gtcaacccaa tcgttatgaa cggtatttca acaggaactt
     7021 ccaaccatga cttcttctct caagtcggaa atggttacct tcttggcgaa gttgaagcca
     7081 tgcaagatga tgactacaac tacggtttgg actaatactc ttcgaaaatc aaattcaaac
     7141 cacgtcagct tcgccttgcc gtactcaagt acagcctgcg gctagcttcc tag
//
LOCUS       DAVLZS010000069         7161 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLZS010000069 DAVLZS010000000
VERSION     DAVLZS010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7161
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.069"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..1437
                     /locus_tag="VYO88_001849"
     CDS             <1..1437
                     /locus_tag="VYO88_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1719893.1"
                     /translation="GVNNWGLSTDIKWLLLSALLSFLGGGVVLFSQGLFYPILLATYG
                     FGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGRLPLKRLMILTLLCQLVAVFTV
                     GYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGLGDRGKDTENQSKWYAFAKEAI
                     EEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANTLYVSPSYLDKEKVVVDAETKQ
                     KLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYGKSGEEASAPLDYEMKAHVSYL
                     SMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDSFISLSSWSINAGKQLFIKGYE
                     SGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETATLILGAIVGIASSLLLFYSVN
                     LLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFVFGASLFILSSRDLVIGLLTLL
                     VFLVSAVLTLYRQAQKESRVSMTIMKGK"
     gene            1439..2080
                     /locus_tag="VYO88_001850"
     CDS             1439..2080
                     /locus_tag="VYO88_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719894.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            2184..3536
                     /locus_tag="VYO88_001851"
     CDS             2184..3536
                     /locus_tag="VYO88_001851"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1719895.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            3540..4598
                     /locus_tag="VYO88_001852"
     CDS             3540..4598
                     /locus_tag="VYO88_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1719896.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            4608..5807
                     /gene="divIB"
                     /locus_tag="VYO88_001853"
     CDS             4608..5807
                     /gene="divIB"
                     /locus_tag="VYO88_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1719897.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     DKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADNIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDLDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
BASE COUNT         2222 a         1217 c         1528 g         2194 t
ORIGIN      
        1 ggggtgaata attggggttt atctactgat atcaagtggc tccttctatc agccctcctt
       61 tccttcctag gtgggggagt cgttcttttt agtcaaggtt tgttttatcc tatcttgtta
      121 gccacctatg gttttgggat tagtttctat ctgttgtttt tattggcgat ttcaatttta
      181 ctaatgcttc tttatctaat gagtttgaat tacaaagcat tagttcccgt tattaagggg
      241 agattacccc ttaaacgcct gatgatttta accctattgt gtcagttagt agctgttttt
      301 acagtaggat acgctgttaa gacaggtttg acgtcttacc aacgattgaa agaacttgaa
      361 atttcaaaac aagcatggca ggatagagca gactattatc aaatttcttt tggcttaggt
      421 gatagaggaa aagatacaga aaatcagagc aagtggtatg cctttgccaa ggaagcaatc
      481 gaagaagaac aagctcttta tgtaaaggat aatctgctcc attttgccaa tccacaagga
      541 aaaaatgaac agggagagac actggatacc tatagtccag atgctaatac gctctatgtt
      601 agtcccagtt atttggacaa ggaaaaggtc gtggtagatg ctgagaccaa acagaagtta
      661 gcccatctcc aaaaaggtga gtttatcctc ttgctcccag aacatttgcg ctctcgagaa
      721 gcagaactta agaaagtttt tgaagaaaga ttgagttatt atggaaaatc tggtgaggag
      781 gcaagtgctc ctttggatta tgagatgaaa gcgcacgtta gttatctttc aatgggagaa
      841 aagcggtttg tttataataa cggtgagaat cccgtatcta ctcagtattt gactgatccg
      901 attttagttg tattcacgcc gacttctaca ggtgatagtt ttatatcctt atctagttgg
      961 tctatcaatg ctggaaaaca actctttatc aaaggatatg agagtgggct agaactcttg
     1021 aagaaagctg gaatttatga gcaagtatcc tatcttaaag aaggaagaag tgtttatcta
     1081 actcgttata atgaagttca aactgaaaca gcaactttaa tcttaggagc tattgttgga
     1141 atagctagtt ccttgttact cttttattct gtcaatcttc tatatttcga gcaattccgc
     1201 cgagatatct tgattaaacg aatttcaggt ttacgatttt ttgaaacaca tgctcagtat
     1261 atggttagcc aatttgccag ttttgtattt ggtgctagtc tctttatttt aagcagtcga
     1321 gacttggtga ttggcttgct cactttattg gtctttctag ttagtgcagt tttgacgctt
     1381 taccgtcaag cgcagaaaga atctcgtgtt tctatgacaa ttatgaaagg aaaataggat
     1441 gattgaacta aagaatatat ctaaaaaatt tggaagccgt cagctatttt cagatacgaa
     1501 tcttcatttt gaaggtggga aaatttatgc cttaatcggt acaagtggct gtggtaagac
     1561 aacactcttg aatatgattg gacgattaga gccatatgac aaagggcaaa tcatatatga
     1621 tggcacttct cttaaggaca ttaagccttc tgttttcttt agagattact taggatactt
     1681 atttcaagat tttggcttaa ttgaaagcca aaccgtcaaa gagaatctca atctgggttt
     1741 agttggtaaa aagttgaagg aaaaagagaa aatctctttg atgaaacaag ctctaaaccg
     1801 tgtaaacctc tcttatttgg atttgaagca acctatattt gagttatcag gaggagaagc
     1861 acaacgtgtt gcactagcga agataatttt aaaggatcca cctttgatcc tcgcagatga
     1921 accaaccgct tccttagacc ccaaaaactc tgaggaatta ctttccatcc tagaatcttt
     1981 aaaaaatccg aatcggacca ttattattgc gacccataat cctctgattt gggagcaagt
     2041 ggatcaggtc attcgagtta ccgatttatc acatagatga tatggtaaga ttcagtcaga
     2101 agaaagagtc acaaacacac tttgtggctt ttttatttcc ataaaaatgg taaaatagta
     2161 ggagtagaaa tggagttcga gacatgaaag taatagatca atttaaaaat aagaaagtcc
     2221 ttgttttagg cttggccaag tctggtgaat ctgcagctcg tttgttggac aagctaggtg
     2281 ccattgtgac agtaaatgat gggaaacctt tcgaggacaa tccagctgcc caaagtttgc
     2341 tggaagaagg gatcaaggtc attacaggtg gccatccttt ggaactcttg gatgaagagt
     2401 ttgcccttat ggtgaaaaat ccaggtatcc cctacaacaa tcccatgatt gaaaaggctt
     2461 tggccaaggg aattccagtc ttgactgagg tggaattggc ttatttgatt tcagaagcac
     2521 cgattattgg tatcacagga tcgaacggta agacaaccac aacgactatg attggggaag
     2581 ttttgactgc tgctgggcaa catggtcttt tatcagggaa tatcggctat ccagctagtc
     2641 aggttgctca aatagcatca gataaggaca cgcttgttat ggaactttct tctttccaac
     2701 tcatgggtgt tcaagaattc catccagaga ttgcggttat taccaacctc atgccaactc
     2761 atatcgacta ccatgggtca ttttcggaat atgtagcagc caagtggaat atccagaaca
     2821 agatgacagc agctgatttc cttgtcttga actttaatca agacttggca aaagacttga
     2881 cttccaagac agaagccact gttgtaccat tttcaacact tgaaaaggtt gatggagctt
     2941 atctggaaga tggtcaactc tacttccgtg gtgaagtagt catggcagcg aatgaaatcg
     3001 gtgttccagg tagccacaat gtggaaaatg cccttgcgac tattgctgta gccaagcttc
     3061 gtgatgtgga caatcaaacc atcaaggaaa ctctttcagc cttcggtggt gtcaaacacc
     3121 gtctccagtt tgtggatgac atcaagggtg ttaaattcta taacgacagt aaatcaacta
     3181 atatcttggc tactcaaaaa gccttatcag gatttgacaa cagcaaggtc gtcttgattg
     3241 caggtggttt ggaccgtggc aatgagtttg acgaattggt gccagacatt actggactca
     3301 agaagatggt catcctgggt caatctgcag aacgtgtcaa acgggcagca gacaaggctg
     3361 gtgtcgctta tgtggaggcg acagatattg cagatgcgac ccgtaaggcc tatgaacttg
     3421 cgactcaagg agatgtggtt cttcttagtc ctgccaatgc cagctgggat atgtatgcta
     3481 actttgaagt acgtggcgac ctctttatcg acacagtagc ggagttaaaa gaataaaata
     3541 tgaaaaaaat tgtctttaca ggtgggggga cggttggaca cgttaccctc aatcttttgt
     3601 taatgcccaa gttcatcgaa gatggttggg aagtccacta tatcggggac aagcgtggta
     3661 tcgaacacca agaaatcctt aagtcaggtt tggatgtcac cttccattct attgcgactg
     3721 ggaaattgcg tcgctatttc tcttggcaaa atatgctgga cgtcttcaaa gttggctggg
     3781 gaatcgtcca atcgctcttt atcatgttgc gactgcgtcc acagaccctt ttttcaaagg
     3841 ggggctttgt ctcagtaccg cctgttatcg ctgcgcgtgt gtcaggagtg cctgtcttta
     3901 ttcacgaatc tgacctgtct atgggcttgg ccaataaaat cgcctataaa tttgcgacta
     3961 agatgtattc aacctttgaa caagcttcga gtttggctaa ggtcgagcat gtgggagcgg
     4021 tgaccaaggt ttcggacaaa aacactccag aaccagatga attggtggat attcaaaccc
     4081 actttaatcc caaattgcca actgtattgt ttgtcggcgg ttctgcaggc gctcgtgtct
     4141 ttaaccaatt ggtgacagac cataagaaag aactaacaga gcgctacaat attatcaatc
     4201 taactggaga ttctagcctg aatgagttga gccaaaatct ttttcgtgtt gactatgtga
     4261 ccgatctcta tcaacccttg ttggaattgg ctgatattgt tgtgacacga ggtggtgcca
     4321 atacgatttt tgagctcttg gcgatagcaa aattgcatgt cattgtgccg cttggtcgtg
     4381 aagctagtcg tggtgaccag attgaaaatg cagcttactt tgtaaaaaaa ggctatgcag
     4441 aagaccttca agaaagcgat ttgaccttgg atagtttgga agagaagctt tctcacttac
     4501 taagtcacaa ggaagattac caagctaaga tgaaagcttc taaggaattg aaatctctag
     4561 cagattttta tcaattgttg aaaaaagatt tatcataagg aaagtaaatg tcaaaagata
     4621 agaaaaatga ggacaaagaa atcctcgaag aattgaaaga gttatcagaa tggcagaaac
     4681 gaaaccaaga atatctaaaa aagaaggctg aagaagaagc ggctctagct gaggagaagg
     4741 acaaggaaag acaagctcgg atgggagaag aatctgagaa gtcagaggac aaacaggacc
     4801 aggagagtga aacagaccag gaagattcag aatcagctaa ggaagagtct gaagaaaaag
     4861 tagcatcctc agaggctgac aaagagaaag aagagaaaga agaaccagag tctaaagaga
     4921 aggaggaaca ggataaaaag cttgctaaaa aggctacaaa ggaaaaacca gccaaagcaa
     4981 agattcctgg tatccatatc ttgcgagcct tcacgatttt atttccaagt ctgcttttat
     5041 tgattgtctc tgcctacttg ctcagtcctt atgcgaccat gaaagatatt cgtgttgagg
     5101 gaacggtgca aactacagct gataatattc gacaggcttc aggcattcag gattcggatt
     5161 atacgattaa ccttctgcta gacaaggcaa aatatgaaaa gcagattaag tctaactatt
     5221 gggttgaatc agctcaactt gtctatcaat ttccaactaa gttcactatt aaggtcaagg
     5281 aatatgatat tgtggcctac tatatttctg gtgaaaatca ttatcctatt ctttccagtg
     5341 gtcagcttga gactagttct gtgagcctga acagtttacc agaaacttat ttatcagttc
     5401 tctttaatga tagtgaacaa atcaaggttt ttgtctcaga acttgctcaa attagcccag
     5461 aactcaaggc ggctatccaa aaggtggaat tagccccaag caaggtgaca tccgatttaa
     5521 ttcgattgac tatgaatgat ttggacgaag tcttggttcc gctttctgaa atgagcaaga
     5581 aactgcctta ttatagtaag attaagccac aattgtcaga accgagtgtg attgacatgg
     5641 aagctggaat ttacagttac actgtggcgg ataaattaat tatggaagct gaggaaaaag
     5701 ccaaacaaga ggctaaggaa gctgagaaaa aacaagaaga agaacagaaa aaacaagagg
     5761 aagagagcaa tcgaaaccaa acgacccagc gctcatcgcg tcgctaggtt taccttttct
     5821 cttatagttc tttagtgacc atgtttttac gtttaatatt tgacatctgt ttttctttat
     5881 gttacatctg caatgtaatc gattacaaaa taatttttga tgaagaaggt aacacatatg
     5941 tcagatgaag tattcttatt tgaagaaatt gaagaaatcg tagcccctac agatggtgaa
     6001 tttttggggg aagttttact tggaactggg gtagttctct taattggagt agcctgttgt
     6061 taaaaagata gggagtgata atcatgcaag ataacttttt atttgaggaa atttcagtac
     6121 cagttagtga tttttcagct ggacttgcaa caggtatcgg atttggttta gcaatccttg
     6181 ctcttgctgg ttgttgaagt ttgttcattt actaacatca agctttttca atttcatttt
     6241 agacagtcat ttaaattttc cgtattagtc ttgcagcaag agattaatag aattagtcat
     6301 tattttattg attgcggact gagggactag agtatgtttt acttaacccc tcttttattt
     6361 attaaaggtt aggtttgtta tgagaattgt tgataagatt aagatattac ctactcctta
     6421 tgagggacac tatcatttat atataccatc cagtaagaaa catgtattag ttgggaaaca
     6481 ggaaaaaaat ggttagagca actaataggt caagaattta ccatatcgga cttattagtg
     6541 ttagtaggga agaaatattt ttaaaatatc ttgggacttt aatataacat tatctgaaaa
     6601 attaaactat aaaagattta ataagaattt tgaaaaaatc ctatttggta ttttcccatt
     6661 ggctcttatt ttgcaatgtt ttattatgta tatttatagg gcggatattt tgactaattt
     6721 ccaaaacttt ccaataacgc taaacattct tttattttgg ttgcttgttg ttattatatc
     6781 tgcaacgata catgaattta gtcatgcaat aattgctaat aattatcaaa ttgagatccc
     6841 aaattgtgga ataatgctac ttttgtttaa tttggctttt tttgtagatt taagtggggt
     6901 gcaattttta aaaaataaaa aacaattttt gaaaattatg ttagcaggaa ttgcttcaaa
     6961 ttcgatttta tcacttacag gtttacttgt tttattgttc acatcgtata aattgcttgg
     7021 actcttatta tttatcatta acttaggtat gatttttatt aaatcaattc ctttttttca
     7081 gtatgatagt ggtattattt taagatactt gaattctaac aataataact tgaattttca
     7141 atatatagtt caacttttaa t
//
LOCUS       DAVLZS010000070         7035 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLZS010000070 DAVLZS010000000
VERSION     DAVLZS010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.070"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(241..1134)
                     /locus_tag="VYO88_001854"
     CDS             complement(241..1134)
                     /locus_tag="VYO88_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1719898.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICSDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKDSLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(1888..2118)
                     /gene="blpU"
                     /locus_tag="VYO88_001855"
     CDS             complement(1888..2118)
                     /gene="blpU"
                     /locus_tag="VYO88_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1719899.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(2321..2611)
                     /locus_tag="VYO88_001856"
                     /pseudo
     CDS             complement(2321..2611)
                     /locus_tag="VYO88_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2657..2890)
                     /locus_tag="VYO88_001857"
     CDS             complement(2657..2890)
                     /locus_tag="VYO88_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1719900.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(2896..3888)
                     /gene="plsX"
                     /locus_tag="VYO88_001858"
     CDS             complement(2896..3888)
                     /gene="plsX"
                     /locus_tag="VYO88_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1719901.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQSLSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTIDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(3885..4655)
                     /gene="recO"
                     /locus_tag="VYO88_001859"
     CDS             complement(3885..4655)
                     /gene="recO"
                     /locus_tag="VYO88_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1719902.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDASLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(4652..5821)
                     /locus_tag="VYO88_001860"
     CDS             complement(4652..5821)
                     /locus_tag="VYO88_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1719903.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            5970..6980
                     /locus_tag="VYO88_001861"
     CDS             5970..6980
                     /locus_tag="VYO88_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1719904.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLTTLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
BASE COUNT         2003 a         1671 c         1154 g         2207 t
ORIGIN      
        1 attgaaaatt gagtttcatc ctctatacta atgtaggaaa cctattaaaa cattccttta
       61 atccaatata agaatacctt gttccattaa tctctacccg atattataga tagaaccaaa
      121 ttcctatact taaaaggaca aataacgttc caaccataat aaacctcctt tctttttgag
      181 aacgttttct ttataggttt agtatagcaa aaacatgaaa aaaacaacat gacttagaag
      241 tcaggttgtt gggaaatcta tctgtttttc tgctaaaatt ctctgaacta atacctgatc
      301 gtctagcaat tctgctagag aaatcgcctt ttcatagaaa ctttctgcct ctaaaatatt
      361 cttgtctaca aataaagcat attttgcctt tagcaaaaat agatgaggtc ggtaaaaaac
      421 atgtcttgtt ttagcaataa ttttctcaaa tgtttgaata tatatcagac tatcttctgt
      481 ctgaatttgg ataaataggc tcagaagaac tttttccatc tgaactaggc tatccttatc
      541 ttcatattct gaacatagca atactttttg agctaactcc tcaaaatgtt ctttatcttc
      601 taatcccata gcacaacaaa agaaatacaa ttcaataatc aacaaatcat ttacagaaaa
      661 atatttcttt tttaataact gctggaaata ttcttccact aaccctaaac cgtaggtcac
      721 atctgaacta ccataaatat caaaacgagc ttgtgtcaca tccacaatta actgctcttc
      781 ctcaggcaaa ttctcataat agttttcata tatttcctca agtatagctt cttttcgttc
      841 gattcttccc ttatcagcgt aggtttgaga atgaatcagc tcatctttga gttttaggaa
      901 tccttttgga atctctataa ccttaacatc cacaatattc tgtaatgata ctccaagttt
      961 atccgcaatc aataataatt taggaagtgt tgctaaagct tgcccatttt caatacgtgc
     1021 tagctgacga atcgtcaact ctgattcatc gctacaaata tctatctgag tttttccaca
     1081 agatcgccta atagttttga ttttataacc aatttcacgt ttcaactcat ccatagtaat
     1141 actccttaag ttgattacaa agatttcttt ttcttcctaa ttcttttgtc aatcatatat
     1201 aaaacgataa gcgaaaacag cggtagaaca atataactct tttcactcat tatcagctga
     1261 aatcccaggg ttgctagtat cttaaagatg aaaatattca tcaaaaatag aaaaacaaat
     1321 actaaaaaat attttaaaac cttcttcatt tcttttcttc aactttccta atttctacac
     1381 ctattttatc gaaaatatat ataaaactcc aaataaacac ttcgactgca ctttttttgg
     1441 caaaaaatag acagaacaaa catcctacct actaaaaata tgatatgaaa ggaaaatgat
     1501 tttttactga caccctaggc aagcttgaaa caaataaatc attgatagta acacttacga
     1561 catcctattt aaagttcctt caatttctaa tgtccccgct atttctaagc cacctctggt
     1621 atgatctatt cctagtcaga atagataaca ccgttctaaa ttacgattca tagttactcc
     1681 ttttttgact cgttactata agactcctct ttacatgcgc aaaataattt tgattcagat
     1741 tcatcattta tagttttgat tattttttaa tagatttttc tgttttcttc tccgaagact
     1801 ttaaaaattt ttttctaatt aaatcatcca tataaggacc aaatatacca actactaaac
     1861 caataataaa acttttaaaa tccataatta ccaccaacat gtcgctgcat aggccacacc
     1921 tccaagtata gctcctcccg cagcaccagt tgctgcacct tgccatgttc ttgttttaat
     1981 tcctagctga agacctcgta ctgctcctcc tccaacacct gctttggcaa aatctcccca
     2041 attgcatccg ccaccttcaa cgcaagcaag catctcagta tccataattt caaattgtga
     2101 catctttttt gtattcataa cgaatacctc ttttttattt ttaatatttg tcttgttaca
     2161 aacttgacaa gtttagtata acagtatcta ttaatttttt tcatccaaat cttgaattgg
     2221 catcgaaacg tcttgaatta gcttttttgt ttcaaaatca tctctatttt taaaaaagat
     2281 gttttctaat cactttttta ctgttagact tcctgcaaaa ctagaatcct agttcacggt
     2341 tgataatgcc agcaatcaaa ttcattcgta atccgaagcg tttacgatga tttcgatagg
     2401 ttgttgaaaa cattttaaac gtttttactt tagcaaaaat attctcaacc ttgctgctct
     2461 ccttagatag tgcatggtta caggctttgt cttcaagagt taatggctta agtttacttg
     2521 atttcctcgg agtttgtgct tgaggatata tcttcatgag cccttgataa ccactgtcag
     2581 ccaagatttt accagcttgt ccgatatttc tcatttctaa aaaccatcta cttccgttga
     2641 cttggaactc cgattgctat tttccttgaa tgattttaac cacatctcct acgttttgga
     2701 gttggtcaat ttcttcatcg ctgatttcga tactaaattc atcttccaga gtcaagataa
     2761 actccatcaa gtcaacagaa tccgcatcca aatcgtcttt cagactcaag gattctgtca
     2821 cgacaaagtc ctctccctgt cgctcttgga taatggtcac aatacggtca aaaatttctt
     2881 tttctgtcat ctcttttatt ctcctgaaaa ttcacgcgca gtctgggcaa ctacgtctgt
     2941 ttctagcatg gtacgaatct ggcgaatcgt actataaaca gccttggcat cgcttgagcc
     3001 atgagtcttg acaacaggtg ccttaacacc aaacaagacc gctccaccaa catctgaata
     3061 attgagctgt tttttcaaac ctctgaggct gtccttgaga aggagggcac ctagtttcgc
     3121 tcgaagacca ccacctgtaa tagctgtctt gagcaagccc atgattccca tagctgtccc
     3181 ttcgatggat ttgagcacag cgtttcccgt gaaaccatct gccacaacaa catctgcaac
     3241 gccattcatc aaatcacgcg cttccacgtt tccgataaag ttcaaacttt catcagccgc
     3301 cagtaattca taagtttcct tacgaagcgg gtcgcccttg ctactctctg ttccgttgtt
     3361 gagcaaacca acacgtggtt gcgcaatgcc acgaacattc ttggcataga aagaacctag
     3421 gacagcgtat tgatggaggt gctgggctgt attttctgca ttagcaccga ggtcaagcat
     3481 gtcaaaacct ttcccatcta tagtcggcaa tgttgacata agtccaggac ggtcgatatt
     3541 cttgatacga cccacgatga agaatccagc agccaacaaa gcacctgtat tcccagccga
     3601 aaggacagcg tctgcttcac catctttgac agccttggct gccaatacca tactggcatt
     3661 tttcttattc cgaatagctc tcgtaggttc atcatccgaa tcaatcttct catccgtatg
     3721 gataatgctg acgcgctctg tcgctgtcag atattgcttg attttagctt catctccgta
     3781 gagttgaacc tcgatatctg aaaagtcaga tagggattga ttgacaccct caacgatggc
     3841 ctgaggtgcg taatcgcccc ccatggcatc tactgcgatt tttttcattt cttttcctct
     3901 tttagtaatt gtccccagtc tgctagggaa tcaataaatt tctttgattt taggtgaatc
     3961 ccaacgtact cttcatatag ttgatccata aattggcgta gctcttgctt gattccaggc
     4021 ttgagcgaaa tggtctccaa agtctcaaaa tcaatagctt gaaattgatt gagcagatag
     4081 gggatattgg gattgagatg gcaacgtctc tcatcctcat gataatgctc tggacagagg
     4141 caggctccat atttgaaaga aaagtcaaaa gcctgaccaa cccgatggca gaagacacac
     4201 tcattaaaat tgaggctgat tccaaatcga gtcaaaattt gaatttcaaa aatattggtc
     4261 aaaacctgat aatccaagcc tgcttccatc aactccaaag tcttttgcaa aaaagcaaac
     4321 aaggaagcat cctgctgatt gtcctgtaaa ctagcatctg caagagctgc cacataggtc
     4381 gcataggcca tgacaaagag gtcactatta atcttgggaa aagtcatgac ctcatgatag
     4441 tcttcgatgt aactgagtcc gtcatcattg attcgcaaga gaaatcgtgc cagcaccaag
     4501 ggctgaataa caggcgccag cttagactga ccagcgtgtt tgacaaaaaa catgcgtttg
     4561 ccaacctgct ctgtaaaaat tttgacgagc ttgtcatcct cacgaaaatt gcgattgtaa
     4621 agcaccaagc cttgactcgt gatagactga atcatgcttc tctcatgtac tcctcaagtc
     4681 gtttcatggc ttctttgata gtctccatgc tggctgcata agataggcgg acgtagcctt
     4741 ccccgtaacg tccaaaggct gcaccaggga taaaggcaac ggccttcttc tgagcaaaat
     4801 ccttcagaaa agcaaaggag tcttgattgt agcccgctgg aattttagca aaaatataga
     4861 aggcaccgtc tggtttgata atctcaaaac caagagcagt cattttttcg atgatatagt
     4921 cccgacgctg gatatattcc ttcttcatgg gctccgcatc gtttttacca gccgtcaagg
     4981 cttctaccgc agcatgttgc gccatggtat ttgcggcagt gaccaagtac tggtgactct
     5041 tgattaactg ggctgtgaag gtcgccggag cgaaaatcag ccccaaacgc caacctgtca
     5101 tggcatgcga tttagacaaa ccattgataa taatagcctg gtctctcaac atcgttccta
     5161 gagacacatg ggcttcgcct gtgtaggtca attctgagta aacctcatca cagacaacaa
     5221 aaacttcgta cttgcgtaaa acagctgcca aggcctctaa ctgctctcga ctgtaggtaa
     5281 ttcctgtcgg attggctgga tagttgagaa taaccgcctt gagcttatca ccctgctcca
     5341 aaatggcctt ctccaacatc tcaggagtca agacaaaacc attttcagtc gtatcaatct
     5401 caacaatttc tgccccaact aagttaacaa tcggttcata gcctggataa gcaggagctg
     5461 gcaaaagtac cttgtctccc tcttccaaaa tagccgtcaa agtcgcagat aaagcctctg
     5521 tcgccccaat tgtaaccaag atttcatttt caggagcata gtccagttgg tacttttcct
     5581 taacaaagtc actggctgcc tgacgtagag tcagcagacc actcatccct gtatagtagg
     5641 attggttctg atcaatcgct cgcttggccg cctccttgac atggtctggc gttgtaaaat
     5701 caggttcccc caaggtcaaa cgcaagaccc caggaatctc cgaaatagcc tggtcaaact
     5761 gacgaatcaa cgaaacttga attttatcta actgtttatt aaagcgctta gttaagtcca
     5821 tagatacctc ctactttcaa aacgtatctc tattatacta caaaagcctc ccgaccgcaa
     5881 aaatacatta gagaatagct ttccactttc tattttactt ttcctgttta caggtctata
     5941 atggtaacag attctatttg gaggttttta tgtcatttct atcaaaaaat ggagcaggca
     6001 tcttggtctg ccttctcatt tctatcgtat cttggtactt aggaggattc ttccctgtga
     6061 ttggcgcgcc cgtttttgcg atttttatgg gcatgctcct acatcccttt ctctcgtctt
     6121 ataaacaact ggatgctgga ttgaccttta gttccaagaa attgctccag tatgccgtta
     6181 tcttacttgg ttttggtctc aatatctctc aagtcttcgc agttgggcaa tcttcactcc
     6241 ctgtcatcct ttccaccatt tcaatagcct tgattgttgc ctacctcttc cagcgcttct
     6301 ttgccctgga tacaaaactg actaccttga ttggagtagg ttcttctatc tgtgggggtt
     6361 ctgccattgc agcgacagcg cctgttatcc atgctaagga aaaggaagta gcccaagcca
     6421 tctccgttat ctttttcttc aatgtcttgg ctgcgctcat ctttccaacc ctcggcacct
     6481 ggcttcatct atccaatgaa ggcttcgccc tctttgcagg gactgcggtc aacgacactt
     6541 cctctgtaac ggctgccgcc agcgcttggg acagtcttta ccaaagcaat accctcgagt
     6601 ctgcaaccat tgttaaactc acacgtactt tggccattat ccctatcacg ctctttctat
     6661 cctactggca aagtcgccaa caagaaaaca agcaaagcct acaactgaaa aaagtcttcc
     6721 cactttttat cctttacttt atccttgcct ctctcctcac tacactactc acctctctag
     6781 gtgtgtccag tagtttcttt acccctctca aagaactctc taaattcctt attgtcatgg
     6841 ccatgagtgc tatcggtctc aaaaccaatc tggtcgctat ggtcaaatcc agtggaaaat
     6901 ccattcttct tggagccatc tgctggattg ccatcatcct caccactctt ggtatgcaga
     6961 cccttatcgg cattttctaa tactcttcga aaatctcttc aaaccacgtc aacgtcgcct
     7021 tgccgtatat atgtt
//
LOCUS       DAVLZS010000071         7006 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLZS010000071 DAVLZS010000000
VERSION     DAVLZS010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7006
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.071"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            9..1331
                     /locus_tag="VYO88_001862"
     CDS             9..1331
                     /locus_tag="VYO88_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1719905.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            1333..3219
                     /locus_tag="VYO88_001863"
     CDS             1333..3219
                     /locus_tag="VYO88_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV1719906.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYMRNKIILP
                     NSLEENLSYLFEWQKAFKGDGFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRSYEELIEEYFSALYGENWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GLHL"
     gene            3387..3731
                     /locus_tag="VYO88_001864"
     CDS             3387..3731
                     /locus_tag="VYO88_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1719907.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            3741..5153
                     /gene="lacG"
                     /locus_tag="VYO88_001865"
     CDS             3741..5153
                     /gene="lacG"
                     /locus_tag="VYO88_001865"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1719908.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            5222..6901
                     /locus_tag="VYO88_001866"
     CDS             5222..6901
                     /locus_tag="VYO88_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1719909.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKV
                     INDISAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QPISFVLLSLMLVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
BASE COUNT         2115 a         1001 c         1497 g         2393 t
ORIGIN      
        1 ttccggtgat gaacaatatt ttagcgtttt tagaaacaaa agtcgctccg tttggtgaaa
       61 aagttggcaa ccaacggcat ttgaaagcta ttcgtgaagg atttatgatg gcaatgcctt
      121 tgattttagt cggatcttta tttcttattc taatcagttg gcctcaagag gattttacaa
      181 attggctgaa tagtgttgga ttgctaagta tcttgacaac tatgaatcag tcaacagtag
      241 cgattatctc cttggtcgct tgtttcggta ttgcctacag gttgtcggaa ggatatggta
      301 cagatggtcc gtcggcaggg atcatagcct tatccagttt tgtattgatg gcacctcgtt
      361 tttcgagtat ggtttatgat aaaaatgggg agcaggtcaa gcagttattt ggcggcgcaa
      421 taccattttc tagcctgaat gcatcttctt tgtttatggc gattactatt ggattggtta
      481 cagcagagat ttatcgtatg tttatccagc gcggaattac gataaaaatg ccaagtggtg
      541 tcccagatgt ggtaagtaaa tcattttcag ctcttttacc tggctttact acttttgttt
      601 tgtgggcttt ggtcttaaaa ggtcttgaag cggcaggagt tgcaggaggt ctcaacggac
      661 tcctaggtgc aattgttgga acaccgctta agttaattgc aggaacgctt ccaggtatga
      721 ttctatgtgt tattgtaaac tcattctttt ggttctgtgg agttaatggg ggacaagttt
      781 taaatgcttt tgtagaccca gtttggttac aatttactac agaaaaccaa gaagctgtgg
      841 ctgcaggaca aacactccaa cacattatta cattaccgtt taaagattta tttgtattta
      901 ttggtggcgg tggagcgact attggtcttg cgatttgtct cttcctattt agtaagagtc
      961 gtgcgaataa aacattaggt aagctagcta ttataccgtc tatttttaat atcaatacag
     1021 ctattctatt tacgtttcca acagttttaa atccgattat gctgattccg tttattgcta
     1081 ctcctacaat caatgccttg attacctatg tatcaatggc tgtaggatta gtaccctata
     1141 caacaggtgt aatccttccg tggacaatgc caccgattat aggaggcttc cttgcaacag
     1201 gggctagttg gcgaggagct ctattacaag ttgttttgat tttggtttct gtagcaattt
     1261 attatccatt cttcaaaatt gcagataaac gcaatcttga aaaagaaaaa gctactgttg
     1321 gagggaaata agatggttat cagagtattt gatcaacaga aaaatactta ttctagcttt
     1381 gccttagagg aattaagtta ctatatgaat cgggtcttta agactaacat agagcttgtc
     1441 gaggagaagg aagcggatat ttttgtagga ttagtcaata aagaggacag aaaagaccat
     1501 gttcttatct cattagacaa gggtaagggg agaattgagt ctaatacaat tgtaggttta
     1561 cttattggaa tttaccgaat gtttcatgaa tttggggttg tgtatactag accagggcgc
     1621 agacatgact ttgttccaga gttacgattt gaagattttt tagataaaca gctatctata
     1681 gatgaaacag ccagttacta tcatagggga gtatgtatag agggagcgga ttcatttgaa
     1741 aatatactag atttcattga ttggctacct aagattggga tgaacagttt tttcatccag
     1801 tttgaaaatc cttactcttt tttgaaacgt tggtatgaac atgaatttaa tccatatcta
     1861 aataaagaac aattttcaaa tgaattagta caagaattga gtgataggtt ggataaagaa
     1921 ttgcaaaaaa gaggtcttat tcatcatcgt gttggtcatg gatggacagg tgaagtttta
     1981 ggttactctt caaaatttgg ctgggaatca ggtcttagta tttcagagga gaagaaaccc
     2041 tatgtcgctg aaataaacgg gaaacgagaa ttgtttaata cggctccgat tttaaccagc
     2101 ctggattttt caaatccaga tgtagctgat aagatggtag aaattatcaa ggattatgcc
     2161 aagaaaagac ctgatgttaa ctacttacat gtatggttgt cggatgctcg taataatatt
     2221 tgtgaatgcg aaaactgtag acaagaattg gtttcggatc agtatattcg tattctcaat
     2281 caattggata gggctttaac gagtgaggga ttagatacaa agatttgttt tctgctttat
     2341 catgagttgt tatgggcgcc tcagaaagaa aaattagata atcctgaacg ctttaccatg
     2401 atgtttgcac cgattacaag aacatttgaa atgagttatg cagatgtaga ttttgacaat
     2461 tccataccta cgcctaaacc ttatatgcgt aataaaatta tacttccgaa ttctcttgag
     2521 gaaaatttat cttatctttt tgagtggcaa aaagcattta aaggagatgg tttcgtatat
     2581 gactatcctt tagggcgtgc tcattatggc gatttaggct atatgaaaat tagtcaaact
     2641 atttacagag atgtatctta tctttccaac ctacatttga acgggtacat ttcgtgtcaa
     2701 gaattacgtg ccggattccc tcataatttt cctaattatg tcatggggca aatgctctgg
     2761 aagaagacaa gaagttatga agaattgatt gaagaatact tttctgcttt gtatggggaa
     2821 aattggcagt ctgttgttga atatttagaa aaattatcca gttattcctc ttgtgattat
     2881 tttaatgcaa ttggcagccg tcaaagtgat gttttagcga atcattatta tatagcttac
     2941 aatctagctg ataatttttt accaattatt gaggaaaata tttctaagtt attaaatagt
     3001 caaaaggatg aatggaaaca gctcagttat catcgtgaat atgttgttaa gatggcgaag
     3061 gctttatatc ttcaagcaac tggaaaaaca aggcaagctc aagatgaatg gagaaatgtg
     3121 ttgaattata tccgtgggca cgaattgcta tttcaatcta atttggatgt ttatcgtgta
     3181 attgaagtag caaaaaatta cgctggttta cacttataaa tcataagtat agaaaatgaa
     3241 ctaaggtatt cagagaagat tgatcctaaa tattatgaaa tttaaggatt tttaagatat
     3301 ttagggtcaa ctttctattt atatcgtagc gaagtcattt taataatgat gtgtaaaaga
     3361 tggatcaaga ttgaggagga agaaagatga aatcaaaaga agaaataaat atgcttggtt
     3421 ttacaattgt cgcttacgca ggagatgcaa ggtcagattt gatggatgct ttggcgtttg
     3481 cgagagatgg atattttgaa caggcaagag aattggttga gtctgcaaac gactcaatag
     3541 tgtctgccca tcgagaacag actaatttat tagcggagga ggcatatgga gataattttg
     3601 aagtgagctt tattatgatt catggtcaag atactttgat gacaacgatg ctattgtatg
     3661 atcaggtaaa gttttttatt gatgaatatg aacgaattcg aaagattgaa gaacatattg
     3721 gtttgcaatg aggattagtc atggaaaatt tacaggttaa agccttaccg aaggagtttt
     3781 tattaggagc tgctaccgct gcttatcaag tagagggtgc aactagggta gatggcaaag
     3841 gaacaaatat gtgggatgtt tatttgcaag aaaacagtcc gttcttacca gatccggcta
     3901 gtgattttta ttatcgttac gaagaggata tagctttggc ggcagaacat ggtttgcagg
     3961 ctttgcgttt atctatttct tgggttcgta tatttcctga tatagatggg gagcctaata
     4021 tattagctgt tcgttattac catagagtct ttcagtcttg cttaaaacat aatgtgattc
     4081 cgtttgtttc tttacatcat tttgattcgc ctcagaaaat gttagaaaca ggggattggt
     4141 tgaatagaga gaatattgat cgtttcatac gatatgctcg cttttgtttc caagaattta
     4201 cagaagtcaa gcattggttt acaatcaatg aactgatgtc tcttgctgca ggtcaatata
     4261 taggaggtca gtttcctcca aatcatcatt ttcaattatc tgaagcaatt caagcgaatc
     4321 ataatatgtt gttggcgcat gctcttgcag tcctcgaatt tcatcaatta gggattgagg
     4381 gaaaggtagg ttgtattcat gctttaaagc caggctatcc tattgatggg caaaaagaaa
     4441 atattttggc agctaaacgg tatgatgttt ataataataa atttctatta gatggaactt
     4501 ttttgggcta ctacagtgag gacacgcttt ttcacttgaa tcaaatattg gaagctaata
     4561 attctagctt tattattgaa gatggtgatt tagaaattat gaagagagct gcacctctta
     4621 atacgatgtt tgggatgaat tattatcgtt cagaatttat tcgtgaatac aaaggtgaaa
     4681 atagacaaga atttaattca acaggaataa aaggacagtc ttcttttaaa ttaaatgctc
     4741 taggtgaatt tgtaaaaaaa cctggtattc cgacaacaga ttgggattgg aatatttatc
     4801 ctcaagggtt atttgatatg ttgcttcgta tcaaagaaga atatcctcaa catccggtca
     4861 tttatttaac tgaaaatggt acagccctta aagaagttaa gccagagggc gagaatgata
     4921 ttattgatga cagtaagaga atccgttata ttgagcaaca tttacacaaa gttttagagg
     4981 ctcgagatag aggagtcaat attcaaggct attttatatg gtctttgcaa gatcaatttt
     5041 cttgggcgaa tggctacaat aagcgatatg gtcttttctt tgttgattat gaaacacaga
     5101 agagatatat taagaaaagt gctctttggg taaaagggct aaaacggaat taaggttagc
     5161 gatttgactg atgtttaata tgttttaaat atgaggttga attttttata ggaggagttt
     5221 tatggataag ctagtcgctg ccattgaaaa gcaacaaggg aaatttgaaa aaatttctac
     5281 taataactat atgatggcta ttaaagatgg attcattgct actatgcctt taattatgtt
     5341 ttcaagcttt ttgatgatta ttattatgat tcctaaaaat ttcggagtag agttaccgag
     5401 tccagctatt gtctggatga gaaaagtgta tatgttaacc atgggagttt tgggtattat
     5461 tgtttcaggg actgttggaa agtcattagt tggaaatgtt aacagaaaaa tgcctcacgg
     5521 aaaggtaata aatgatattt ctgcaatgtt ggcagccata tgtagttatc tggtattaac
     5581 tgtaacgctt gtagttgatg agaagacggg atctacaagt ttgtcgacaa actatttagg
     5641 atctcaagga ttgataactt cgtttgtcag tgcctttatt actgtaaatg tttaccgatt
     5701 ctgtattaag cgagacatta ctattcattt acctaaggaa gttcctgggg ctatatcaca
     5761 agcttttaga gatatttttc ctttttcttt tgttttactt attagtggtt tgttagatat
     5821 tgtatctcgg tttagtttag atgttccttt tgcccaagta tttcaacaac tattgactcc
     5881 tatttttaag ggggcagaat catatcctgc tatgatgttg atttggttta tgtgtgcttt
     5941 gctttggttt gttggaattc atggaccatc tattgtctta cctgctgtta cagctttaca
     6001 actgagcaat atggaagaga atgctcaact tcttgcaaat gggcagttcc cttatcattc
     6061 tttaacgcct aatttcggaa attatatcgc tgctattgga ggaacggggg ctacctttgt
     6121 tgtaccattt attttgattt tctttatgcg gtctaaacaa ttaaaatcgg taggtaaagc
     6181 tacaattact cctgttttat ttgcggtaaa tgaacctctt ctatttggta tgcctgttat
     6241 tttgaatccc tatctttttg tccctttttt gatgactcca ccagtaaatg tatttctagg
     6301 aaaggtattt attgatttct ttggaatgaa tggattttat atccagttac cttgggcttt
     6361 tcctggtccc ttgggattgt taattggaac gaattttcaa cctatctcct ttgtgctttt
     6421 atctttgatg ttagttgtcg acatattgat ttatttgcca ttctgtagag cgtatgatag
     6481 acagttactg atgaaagaag atgttgcaag ctcaaatgat attattttag aggaggatac
     6541 aagtgaaata atgcctggtg agatagatgt aataaaaagt aaggagttga aagtactggt
     6601 tctttgtgca gggtctggaa caagtgcgca attagccaat gcaattaacg agggcgctca
     6661 attagcagaa gttagagtga ttgcgaattc aggagcgtac ggagctcatt atgatattat
     6721 gggtgtttat gatttaatta ttctggctcc acaagttcgg agttattata gagagatgaa
     6781 ggtggatgca gaaagattag gtattcagat agttgctacc agaggaatgg aatatattca
     6841 tttaacaaag agtccaagta aatccttaca atttgtattg gagcattacc aagctgtgta
     6901 gtaagttttt ccatctttta tttgagtaag gattttgctt acagataggc ttggatttaa
     6961 aaacgttccc ccttttttaa tataagaatc cctctttcac aattgt
//
LOCUS       DAVLZS010000072         6940 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLZS010000072 DAVLZS010000000
VERSION     DAVLZS010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6940
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.072"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            1..486
                     /locus_tag="VYO88_001867"
                     /pseudo
     CDS             1..486
                     /locus_tag="VYO88_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            547..1509
                     /locus_tag="VYO88_001868"
     CDS             547..1509
                     /locus_tag="VYO88_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1719910.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPIESLCYE"
     gene            1686..2693
                     /gene="gap"
                     /locus_tag="VYO88_001869"
     CDS             1686..2693
                     /gene="gap"
                     /locus_tag="VYO88_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1719911.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2760..3596)
                     /locus_tag="VYO88_001870"
     CDS             complement(2760..3596)
                     /locus_tag="VYO88_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1719912.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3722..5917
                     /locus_tag="VYO88_001871"
     CDS             3722..5917
                     /locus_tag="VYO88_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1719913.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTSAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5970..6122
                     /gene="rpmG"
                     /locus_tag="VYO88_001872"
     CDS             5970..6122
                     /gene="rpmG"
                     /locus_tag="VYO88_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1719914.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6132..6308
                     /gene="secE"
                     /locus_tag="VYO88_001873"
     CDS             6132..6308
                     /gene="secE"
                     /locus_tag="VYO88_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1719915.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6363..6899
                     /gene="nusG"
                     /locus_tag="VYO88_001874"
     CDS             6363..6899
                     /gene="nusG"
                     /locus_tag="VYO88_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1719916.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2154 a         1211 c         1504 g         2071 t
ORIGIN      
        1 aaaaatttta atagtttaaa gcacctagca cctgtttaga ttgatgaaac aggattcgat
       61 acttattttt atcgagaata tggtcgctca ttaaaaggtc agttaataag aggtaaagta
      121 tctggaagaa gatatcagag gatttctttg gttgcaggtc taacaaatgg tgagttaatc
      181 gctccgatga cttacgaaga gacgatgacg agcgactttt ttgaagcttg gtttcagaag
      241 tttctcttac caacattaac cacaccatcg gttattatta tggataatgc aagattccat
      301 agaatgggta agttagaact tttatgcgag gagtttgggc ataaactttt acctcttcct
      361 ccctactcac ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc
      421 aaaagggtat taccaagttg caataccttt tatgaggctc ttttgtcttg ttcttgtttc
      481 aattgactat agttcacgga tacagttggg aaagaagcta ttaaacattt ggagagtcct
      541 tttgggatga acatgtcaaa tattactata gatgggcaag aaatggatct gagtcaaacg
      601 atgccttctt atgctcaagt agtgagtctt tatgaggata caagcatctc tgttagtagt
      661 aatgagacgg acaaagtgtt ggctggatcc ctctatactg atacaaatga acagggatta
      721 acgattccaa gcagtttact aaaaaattgg aatgaacaga caggaaaaaa tttgacagct
      781 aatgatctta ttggcaaatc agtctcagcc agcattgtag aaagtgctgc cgaagctagt
      841 aagattgctc aatttcaaac gaagattgta cgtgtaatca atgatgaaga tgacatggag
      901 gacagcaaca gtttcatgct gtctcatcaa atggaaacga ttttgaaaga ggctggattt
      961 acgaaagctg tatcttattt tatcttggaa ctcaaagatc catcacagac aaaagtagta
     1021 acagaagaat tacagaaaaa taagaagtat actgtgcttt ctcaacagag agttcttgat
     1081 attgtgatta cctttattcg tgttattcag ggattattga ttgtgctttc atcacaagct
     1141 attgtggtag cagcggttat gattggtatc attatttaca tcaatatcat gcaacgttcc
     1201 aaggaaatag gtgtcatgaa agcagttggt tatcagaatc gtgatgtcaa aggaattttt
     1261 atttacgagg ctatctggat tgtaggtatc gccttgctgc tggcattttt ggttgcacaa
     1321 ggggtgggaa gtttggcgaa tgcgattgta agtcactttt acccatccat cactaaggtt
     1381 tttgaattaa atcttttatc tgttttagga actctagttt tcgctctatt acttggttat
     1441 gtctcagcct acttcccggc gcgtaagatt agtaaaatgg atcctataga atcgttatgc
     1501 tatgaatagt aagggattcc ttggtttaca gtcttaaaaa gaaactaaca tagaaaaaca
     1561 atggccatac ttgcaattca actcaaatag ttgtataata ggtttgttga aaggtgattt
     1621 gtagtgattc aagttactct tttcacaata aaaatttcat gattttcata aggaggaaat
     1681 cactaatggt agttaaagtt ggtattaacg gtttcggacg tatcggtcgt cttgctttcc
     1741 gtcgtatcca aaacgtagaa ggtgttgaag ttacacgcat caacgacctt acagatccag
     1801 ttatgcttgc acacttgttg aaatacgaca caactcaagg tcgtttcgac ggtactgttg
     1861 aagttaaaga aggtggattt gaagttaacg gtaaattcat caaagtttct gctgaacgtg
     1921 atccagaaca aatcgactgg gctactgacg gtgtagaaat cgttcttgaa gctactggtt
     1981 tctttgctaa gaaagaagca gctgaaaaac accttaaagg tggagctaaa aaagttgtta
     2041 tcactgctcc tggtggaaac gacgttaaaa cagttgtatt caacactaac cacgacgttc
     2101 ttgacggtac tgaaacagtt atctcaggtg cttcatgtac tacaaactgc ttggctccaa
     2161 tggctaaagc tcttcaagac aactttggtg ttgttgaagg attgatgact actatccacg
     2221 cttacactgg tgaccaaatg atccttgacg gaccacaccg tggtggtgac cttcgccgtg
     2281 ctcgcgctgg tgctgcaaac atcgttccta actcaactgg tgctgcaaaa gctatcggtc
     2341 ttgtaatccc agaattgaat ggtaaacttg acggatctgc acaacgcgtt ccaactccaa
     2401 ctggatcagt tactgaattg gtagcagttc ttgaaaagaa cgttactgtt gatgaagtga
     2461 acgcagctat gaaagcagct tcaaacgaat catacggtta cacagaagat ccaatcgtat
     2521 cttcagatat cgtaggtatg tcttacggtt cattgtttga cgcaactcaa actaaagttc
     2581 ttgacgttga cggtaaacaa ttggttaaag ttgtatcatg gtacgacaac gaaatgtcat
     2641 acactgcaca acttgttcgt actcttgaat acttcgcaaa aattgctaaa taattcttga
     2701 gttgatagaa agcaaggctt tgtggtcttg ctttttatat ggaaaaatgg atgacacgat
     2761 catccattct tttttaattc tttttcaaat gtatttgaaa gggtagtgaa agttagcttc
     2821 tctaaagtaa gtgggtgggt aaaggaaagt cggaaggcat gaagcataag ccgacttgtc
     2881 tttgatttac tattatagag agggtcgccc aggataggaa gattatgatg cgaaaggtgc
     2941 acacgaatct gatgggttcg ccctgtcttt agcttgcaac gagccaagga agtcttgttt
     3001 gagaattgct ttaatctgct tacatgcgtt tcagcatatt gcccattttt tgcatcaact
     3061 attctttttc tacgatcatg gcgatcacgt ccaattttgt ctctgaaaac aagttctttt
     3121 ctgttgatat ttccatcaac tagagcccaa tattctctag aaatctcttt tttctccaat
     3181 aagcgattga gaatgggcag gataaaagga tttttggcaa agagaactaa gccactggtt
     3241 tccatgtcca gacgatgaac gacatagcag gtttggccaa cataggtact gacatggtta
     3301 agaagggcaa tttcgtttgg ttgattacca tgcgttttca tcccctctgg tttgtttaca
     3361 ataatcaagt gttgatcttg ataaacttcc tgcactaagt ctgggttgcc ccaagggatc
     3421 gtcttttggg gataatcttc ctcgtcaaaa gtcaactggc aaacatctcc aggatttacg
     3481 atttcgttcc agtggacttc ttcttgattt atcaaaatat gtttcttgat tctcaaaaaa
     3541 tgacggattt ttctagggat gaggagttgt tcctcaagta attgctttac cgtcatttga
     3601 ggtagagagg cgggtaatgt aaatgtgaat tgcatacaga tattgtaaca aaaaaagccc
     3661 tatttggata ggaaatagct aaattcttgt cttcctatga tgaagatgat aaaataaacg
     3721 catgaaatta gataaattat ttgagaaatt tctttctctt tttaaaaaag aaacaagtga
     3781 actagaggac tctgattcta ctatcttacg tcgctctcgt agtgatcgaa aaaaattagc
     3841 ccaagtaggt ccgattcgaa aattctggcg tcgttatcat ctaacaaaga ttatccttat
     3901 actaggtttg agtgcaggat tgctagttgg aatctatttg tttgctgtag ccaagtcgac
     3961 caatgtcaat gatttgcaaa atgccttgaa aactcggact cttatttttg accgtgaaga
     4021 aaaagaggct ggtgccttgt ctggtcaaaa gggaacctat gttgagctga ctgatatcag
     4081 taaaaacttg cagaatgctg ttattgcgac agaagaccgt tctttctata aaaatgacgg
     4141 gattaactat ggccgtttct tcttggctat tgtcactgct ggacgttcag gtggtggctc
     4201 taccattacc caacagctgg ctaaaaacgc ctatttatca caagatcaaa ctgttgagag
     4261 aaaagcgaaa gaatttttcc ttgccttaga attaagcaaa aaatatagta aggagcaaat
     4321 tctaaccatg taccttaaca acgcttattt tggaaatggt gtgtggggtg tagaagatgc
     4381 gagtaagaaa tactttggag tttctgcatc agaagtgagt ctggatcaag ctgcgactct
     4441 ggcagggatg ctcaaggggc cggaactgta taatcccttg aattccgtag aagattctac
     4501 taatcggcgc gatactgtct tgcagaatat ggttgcagca ggatatattg ataaaaacca
     4561 agaaaccgaa gctgctgaag ttgatatgac ttcgcaattg cacgataagt atgaaggaaa
     4621 aatctcagat taccgttacc cctcttattt tgatgcggtg gttaatgaag ctgtttccaa
     4681 gtataatcta acagaggaag agattgtcaa taatggctac cgcatttaca cagagctgga
     4741 ccaaaactac caagcaaata tgcagattgt ttatgaaaac acatcgctat ttccgagggc
     4801 agaggatgga acgtctgctc aatcaggaag tgtagctctc gaaccgaaaa cagggggagt
     4861 tcgtggagtt gtcggtcaag ttgctgacaa tgataaaact ggattccgga atttcaacta
     4921 tgcaacccaa tcaaagcgta gtcctggttc tacaattaag cctttagttg tttatacgcc
     4981 agcagttgaa gcaggctggg ctttgaataa gcagttggat aaccatacca tgcagtatga
     5041 cagctataag gttgataact atgcagggat caaaacgagt cgagaagttc ctatgtatca
     5101 agccttggca gaatcgctta atctacctgc tgttgccact gttaatgatt tgggtgtcga
     5161 caaggctttt gaggcaggcg aaaaattcgg actcaacatg gaaaaggtcg accgtgttct
     5221 tggtgtcgcc ttgggaagcg gtgttgaaac caaccctctt caaatggctc aagcatacgc
     5281 tgcctttgca aatgaaggtt taatgcctga agctcatttt attagtagaa ttgaaaatgc
     5341 tagtggacaa gttattgcga atcataaaaa ttcacaaaaa cgggtgattg ataagtctgt
     5401 agctgacaag atgaccagta tgatgttggg gactttcacc aacggtaccg gtattagttc
     5461 atcgcctgca gactatgtca tggcagggaa aactggaaca actgaagcag ttttcaatcc
     5521 ggagtacaca agtgaccagt gggtaattgg ttatactccg gatgtagtga ttagccactg
     5581 gcttggcttt ccgaccactg atgaaaatca ctatctagct ggctctactt caaacggtgc
     5641 agctcatgtc tttagaaaca ttgccaatac cattttacct tatacgccag gaagtacctt
     5701 tacggttgaa aatgcttata agcaaaatgg aattgcacca gccaatacaa aaagacaagt
     5761 acaaaccaat gataatagcc agacagatga taatttgtct gatattcgag ggcgtgcgca
     5821 aagtctagta gatgaggcta gccgggctat ctcagatgcg aagattaagg aaaaggctca
     5881 aacaatatgg gattcgatag tcaatctatt tcgctaagat gcttgtcaaa gcctagcttt
     5941 cttgttataa tggataagat ggaggcgtta tggcactaaa aaaagcaagc ctagcttgtg
     6001 cggtttgtgg ttcgagaaac tattcaatca agatcagcgg aaaccccaag cctacacgac
     6061 tagaagtaaa taaattttgt aagcattgtg gcaagtacac tacacacaga gaaacgagat
     6121 aggagagagc gatgcgtttt attggagata tttttagact tcttaaagac acaacgtggc
     6181 caactcgcaa ggaaagctgg agagattttc gttctatcat ggaatacaca gctttctttg
     6241 tagtaattat ttacattttt gaccagttga ttgtttcagg tttgattcga tttattaaca
     6301 ttttttagaa gattagtgga gttaattaca ctagaaatct tctatttatg aaaggaaata
     6361 tcatggatag ttttgataaa ggatggtttg ttttacaaac ttattctggt tatgaaaata
     6421 aggtgaaaga aaatctatta caacgtgcac aaacctacaa tatgttggat aatattctac
     6481 gcgttgaaat tccaacacaa acagtgcaag ttgaaaaaaa tggaaagaga aaagaagtag
     6541 aagaaaatcg ctttccaggt tatgttcttg tagaaatggt catgacagat gaagcttggt
     6601 ttgttgttcg aaacacacca aatgttacag gatttgtcgg atcacacggg aacagatcaa
     6661 aaccaactcc attattggaa caagaaattc gcgacatttt ggtatctatg ggacaaactg
     6721 ttcaagaatt tgatttcgat gttgagattg gtcaaactgt acgtattatt gatggtgctt
     6781 ttgcagacta cactggtaag attacagaaa ttgataataa caaagtgaaa atgattatct
     6841 ctatgtttgg taatgacaca gttgcagaag taaatctaaa ccaaatcgca gaattataac
     6901 cctgagagag gctggagcct ctcttttttg tgcagtttag
//
LOCUS       DAVLZS010000073         6871 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLZS010000073 DAVLZS010000000
VERSION     DAVLZS010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.073"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..299)
                     /locus_tag="VYO88_001875"
     CDS             complement(<1..299)
                     /locus_tag="VYO88_001875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719917.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     SKHCFEVVDRTDEVSSKHCFEVVDRTDEVSNHIYGKVKLTWFEEIFEEYKSLHNKT"
     gene            complement(353..649)
                     /locus_tag="VYO88_001876"
     CDS             complement(353..649)
                     /locus_tag="VYO88_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1719918.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            871..1635
                     /locus_tag="VYO88_001877"
     CDS             871..1635
                     /locus_tag="VYO88_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1719919.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            2200..3579
                     /locus_tag="VYO88_001878"
     CDS             2200..3579
                     /locus_tag="VYO88_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1719920.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3593..4258
                     /locus_tag="VYO88_001879"
     CDS             3593..4258
                     /locus_tag="VYO88_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1719921.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4393..4551
                     /locus_tag="VYO88_001880"
     CDS             4393..4551
                     /locus_tag="VYO88_001880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719922.1"
                     /translation="MKIKDQTRKLATGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            4613..5152
                     /locus_tag="VYO88_001881"
     CDS             4613..5152
                     /locus_tag="VYO88_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1719923.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYKENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            5219..5629
                     /locus_tag="VYO88_001882"
     CDS             5219..5629
                     /locus_tag="VYO88_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1719924.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5745..>6871
                     /gene="pavB"
                     /locus_tag="VYO88_001883"
     CDS             5745..>6871
                     /gene="pavB"
                     /locus_tag="VYO88_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1719925.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLG"
BASE COUNT         1871 a         1340 c         1566 g         2094 t
ORIGIN      
        1 gttttattat gtagagactt atactcttcg aaaatctctt caaaccacgt cagtttcacc
       61 ttgccgtaga tatggttact gacttcgtca gttctatcta caacctcaaa acagtgtttt
      121 gagctgactt cgtcagttct atctacaacc tcaaaacagt gttttgagct gacttcgtca
      181 gttctatcta caacctcaaa acagtgtttt gagctgactt cgtcagttcc atccacaacc
      241 ttaaaacagt gttttgagca gcctgcggct aacttcctag tttgcacttt aattttcatt
      301 gagtattact tcatcttctc ctgaaattga gtttttgccc agctcctctt gattattcta
      361 cttgaccggg ccaagcattc ataccacctt ctacgttggt aacggtgagg ccttgggagc
      421 tgagaaattg gcaggtagat gcagagcgga ctcctccttg acaaataaca tagtattcat
      481 ggtcaggttt gagttctttg tagccttgct ctaaggtact taatggaaga tttttggcat
      541 ctggtgcatg tcctgcttgg aattcatgtg cttcacggac atcgataagt tctagatttt
      601 cattttgata ttttccataa aagtcagcca tgctgatact agtttccata ttctactcct
      661 tctgggttag tcattttgta tagtgaataa gcgccgtcaa ggttttggac ggtaaatcct
      721 gcttgcttga ggataggctc tgcgatatag ctgcgcaaac cactgtggca gctgacgatg
      781 taggcttgtt tttctcctca gttcatcagc ttcctccttg acactttgtc agattttgat
      841 acaatagtac aaaattagag gaggcaggct atgattcaga aacatgcgat tcctatttta
      901 gagtttgatg acaatcctca ggcggttatc atgcccaatc acgaggggct ggacttgcag
      961 ttgccaaaga agtgtgttta tgcattttta ggtgaggaga ttgaccgcta tgcaagggaa
     1021 gtaggggcgg attgtgtcgg cgaattcgtt tctgctacca agacctatcc agtctatgtc
     1081 atcaactaca agggtgagga ggtctgtctg gctcaggctc ctgttggctc cgctccagca
     1141 gcccagttta tggattggtt gattggctat ggtgtggagc agattatctc tactgggacc
     1201 tgtggtgtgc tagccgatat agaggaaaat gcctttctag tccctgttcg cgctctgcga
     1261 gatgagggag ccagttacca ctatgtggca ccttgtcgtt atatggaaat gcagccagag
     1321 gctattgctg ctattgagga agttttggaa gacagaggga ttccttatga agaagtcatg
     1381 acctggacga cagacggttt ttaccgagaa acggctgaaa aggtggctta tcgtaaggaa
     1441 gaaggctgtg ctgttgtgga gatggagtgt tctgctcttg cggcagtagc tcaattgcgt
     1501 ggggttctct ggggtgaatt gttgttcaca gcagattctc tagcggactt ggaccagtac
     1561 gacagtcgtg actggggctc ggaagctttt aataaggcgc tagaactgag tttagcaagt
     1621 gttcaccacc tttagttgta caggcaaagg atttgtttta tcataaaatg tctagctcat
     1681 acttttcaaa aatatgttta aacgaggtca ccttcctctt gtcctaggca tgttgaggtt
     1741 gggaaaaatc tttaaaatca gaaaaacgta tcatatcagg tgatgaaaat tttgatacta
     1801 tgcgttttat gttggtaaga tttagagtga gatgaaatga tactcttcga aaatctcttc
     1861 aaaccaggtc agcttcacct tgccgtatag atgttactga cttcgtcagt tctatccaca
     1921 acctcaaaac agtgttttga gcaacctgtg actagctttc taagcgatgc cttggttctc
     1981 attgcctata atcaaaaaga gaaattttct cctgaaaagc atatagagta gctggcgtta
     2041 aaagctcctg tcttgctttt ttgacctata gtcacatcta tcaagtattg ttcttgccta
     2101 agctatcaat aaaaaggtgg cattttttag gcttggtgtt agtgaatttt gccttatcct
     2161 atctaagtca tttcgagctt tttatggtac aatggaaaca tgttattcaa attatctaag
     2221 gaaaaaatag agctaggctt atctcgttta tcgccagccc gtcgtatttt tttgagtttt
     2281 gccttggtca ttttactagg ctctcttctt ttgagcttgc cctttgtcca agttgaaagc
     2341 tcacgagcga cttattttga tcatcttttc actgctgtct ctgcagtctg tgtgacaggt
     2401 ctctcaaccc ttccagtagc tcacacctat aatatctggg gccaaataat ctgtttgctc
     2461 ttgattcaga tcggtggtct agggctcatg acttttattg gggttttcta tatccagagc
     2521 aagcaaaagc ttagtcttcg tagccgtgca actattcagg atagttttag ttatggagaa
     2581 actcgatctt tgagaaagtt tgtctattct atttttctca cgaccttttt ggttgagagc
     2641 ttgggagcta ttttgcttag ttttcgcctt attcctcaac ttggctgggg acgtggtctt
     2701 tttagttcca tttttctagc gatctcagcc ttctgtaatg ccggttttga taatttaggg
     2761 agcaccagtt tatttgcttt tcagaccgat ttactggtca atctggtgat tgcaggcttg
     2821 attattacag gcggccttgg ttttatggtc tggtttgatt tggctggtca tgtaggaaga
     2881 aagaaaaaag gacgtctgca ctttcatacg aagcttgtac tattattgac tataggtttg
     2941 ttgttatttg gaacagcaac tactctcttt cttgagtgga acaatgctgg aacgattggc
     3001 aatctccctg ttgccgataa ggttttagtt agcttttttc aaacagtgac gatgcgaaca
     3061 gctggctttt ctacgataga ttatactcag gctcatcctg tgactctttt gatttatatc
     3121 ttacagatgt ttctaggtgg ggcacctgga ggaacagctg ggggactcaa gattacgaca
     3181 ttttttgtcc tcttggtctt tgcacgaagt gagcttctag gcttgcctca tgccaatgtt
     3241 gcgagacgaa cgatcgcgcc gcgaacggtt caaaaatcct ttagtgtctt tattatcttt
     3301 ttgatgagct tcttgatagg attgattctg ctagggataa cagccaaagg caatcctccc
     3361 tttatccacc tcgtatttga aaccatttca gctcttagta cagttggtgt aacggcaaat
     3421 ctgactcctg accttgggaa attggctctc agtgttatca tgccacttat gtttatggga
     3481 cgaattggtc ccttgacctt gtttgttagc ttggcagatt accatccaga aaagaaagat
     3541 atgattcact atatgaaagc agatattagt attggttaag aaaggaaaga gcatgtcaga
     3601 tcgtacgatt ggaattttgg gcttgggaat ttttgggagc agtgtcctag ctgccctagc
     3661 caagcaggat atgaatatta tcgctattga tgaccacgca gagcgcatca atcagtttga
     3721 gccagttttg gcgcgtggag tgattggtga catcacagat gaagaattat tgagatcagc
     3781 agggattgat acctgcgata ccgttgtagt cgcgacaggt gaaaatctgg agtcgagtgt
     3841 gcttgcggtt atgcactgta agagtttggg ggtaccgact gttattgcta aggtcaaaag
     3901 tcagaccgct aagaaagtgc tagaaaagat tggagctgac tcggttatct cgccagagta
     3961 tgaaatgggg cagtctctag cacagaccat tcttttccat aatagtgttg atgtctttca
     4021 gttggataaa aatgtgtcta tcgtggagat gaaaattcct cagtcttggg caggtcaaag
     4081 tctgagtaaa ttagacctcc gtggcaaata caatctgaat attttgggtt tccgagagca
     4141 ggaaaattcc ccattggatg ttgaatttgg accagatgac ctcttgaaag cagataccta
     4201 tattttggca gtcatcaaca accagtattt ggatacccta gtagcattga attcgtaaag
     4261 agggatgacc cctctttttt gatgcctaag atggcaaata gagacagaag ccccttgtct
     4321 tctagtaaaa gttcttcaaa ggctggactt tatggtaaaa tagaaagaag tgacaagaga
     4381 gagtaatact caatgaaaat caaagatcaa actaggaaac tagctacggg ctgctcaaaa
     4441 cactgttttg aggttgtgga tagaactgac gaagtcagct caaaacactg ttttgaggtt
     4501 gcagatagaa ctgacgaagt cagtaacatc tatacggcaa ggcgacgttg acgcggtttg
     4561 aagagatttt cgaagagtat aagaaaaaat cagtccccta aaggagtaga ttatgaagtt
     4621 attgtctatc gcaatttcta gctataatgc agcagcctat cttcattact gtgtggagtc
     4681 gctagtgatt ggtggtgagc aagttgggat tttgattatc aatgacgggt ctcaggatca
     4741 gactcaggaa atcgctgagt gtttagctag caagtatcct aatatcgtta gagccatcta
     4801 taaggaaaat aaatgccatg gcggtgcggt caatcgtggc ttggcagagg cttctgggcg
     4861 ctattttaaa gtagttgaca gtgatgactg ggtggatcct cgtgcctact tgaaaattct
     4921 tgaaaccttg caggaacttg agagcaaagg tcaagaggtg gatgtctttg tgaccaattt
     4981 tgtctatgaa aaggaagggc agtctcgtaa gaagagtatg agttacgatt cagtcttgcc
     5041 tgttcggcag atttttggct gggaccaggt cggaaatttc tccaaaggcc agtataccat
     5101 gatgcactcg ctgatttatc ggacagattt gttgcgtgct agccagttct aactgcctga
     5161 acatactttt tatgtcgata atctctttgt ctttacgccc cttcagcagg tcaagaccat
     5221 gtactatctg cctgtcgatt tctatcgtta tttgattggg cgtgaggacc agtctgtcaa
     5281 tgagcaagtg atgattaagt gcattgacca gcaactcaag gtcaatcgac tcttgataga
     5341 ccaacttgat ttgtcccaag tgagtcatcc caaaatgcga gaatatctgc tgaatcatat
     5401 tgaactcacg acggtgattt ccagtaccct gctcaaccga tctggaacag cggagcatct
     5461 ggcaaaaaaa cgccaattgt ggacctatat tcagcagaaa aatccagaag tctttcaggc
     5521 tattcgtaag accatgttga gccgtttgac caaacattct gtcttgccag atcgcaaact
     5581 gtccaatgtc gtctatcaaa tcaccaaatc tgtttatgga tttaattaat ataagtgttt
     5641 tataagaggg atttaagaaa aattttaact ttttcttagt cctttttaat ttcaggagat
     5701 tatactagag tcatcaaata aagaaagact ctaaggagaa tcctatgaaa ttcaatccaa
     5761 atcaaagata tactcgttgg tctattcgcc gtctcagtgt cggtgttgcc tcagttgttg
     5821 tggctagtgg cttctttgtc ctagttggtc agccaagttc tgtacgtgcc gatgggctca
     5881 atccaacccc aggtcaagtc ttacctgaag agacatcggg aacgaaagag ggtgacttat
     5941 cagaaaaacc aggagacacc gttctcactc aagcgaaacc tgagggcgtt actggaaata
     6001 cgaattcact tccgacacct acagaaagaa ctgaagtgag cgaggaaaca agcccttcta
     6061 gtctggatac actttttgaa aaagatgaag aagctcaaaa aaatccagag ctaacagatg
     6121 tcttaaaaga aactgtagat acagctgatg tggatgggac acaagcaagt ccagcagaaa
     6181 ctactcctga acaagtaaaa ggtggagtga aagaaaatac aaaagacagc atcgatgttc
     6241 ctgctgctta tcttgaaaaa gctgaaggga aaggtccttt cactgccggt gtaaaccaag
     6301 taattcctta tgaactattc gctggtgatg gtatgttaac tcgtctatta ctaaaagctt
     6361 cggataatgc tccttggtct gacaatggta ctgctaaaaa tcctgcttta cctcctcttg
     6421 aaggattaac aaaagggaaa tacttctatg aagtagactt aaatggcaat actgttggta
     6481 aacaaggtca agctttaatt gatcaacttc gcgctaatgg tactcaaact tataaagcta
     6541 ctgttaaagt ttacggaaat aaagacggta aagctgactt gactaatcta gttgctacta
     6601 aaaatgtaga catcaacatc aatggattag ttgctaaaga aacagttcaa aaagccgttg
     6661 cagacaacgt taaagacagt atcgatgttc cagcagccta cctagaaaaa gccaagggtg
     6721 aaggtccatt cacagcaggt gtcaaccatg tgattccata cgaactcttc gcaggtgatg
     6781 gcatgttgac tcgtctcttg ctcaaggcat ctgacaaggc accatggtca gataacggcg
     6841 acgctaaaaa cccagcccta tctccactag g
//
LOCUS       DAVLZS010000074         6816 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLZS010000074 DAVLZS010000000
VERSION     DAVLZS010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6816
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.074"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(119..394)
                     /locus_tag="VYO88_001884"
     CDS             complement(119..394)
                     /locus_tag="VYO88_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1719926.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(501..1340)
                     /locus_tag="VYO88_001885"
     CDS             complement(501..1340)
                     /locus_tag="VYO88_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1719927.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMETILAHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRAVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1482..2330
                     /locus_tag="VYO88_001886"
     CDS             1482..2330
                     /locus_tag="VYO88_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1719928.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2423..3340)
                     /locus_tag="VYO88_001887"
     CDS             complement(2423..3340)
                     /locus_tag="VYO88_001887"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1719929.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVEQLKADEEVTRNWS"
     gene            3777..3982
                     /locus_tag="VYO88_001888"
                     /pseudo
     CDS             3777..3982
                     /locus_tag="VYO88_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4187..4480)
                     /gene="rpmA"
                     /locus_tag="VYO88_001889"
     CDS             complement(4187..4480)
                     /gene="rpmA"
                     /locus_tag="VYO88_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1719930.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4497..4841)
                     /locus_tag="VYO88_001890"
     CDS             complement(4497..4841)
                     /locus_tag="VYO88_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1719931.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4857..5171)
                     /gene="rplU"
                     /locus_tag="VYO88_001891"
     CDS             complement(4857..5171)
                     /gene="rplU"
                     /locus_tag="VYO88_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1719932.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5207..5294)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5353..6057)
                     /locus_tag="VYO88_001892"
     CDS             complement(5353..6057)
                     /locus_tag="VYO88_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1719933.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6459..6758
                     /locus_tag="VYO88_001893"
     CDS             6459..6758
                     /locus_tag="VYO88_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1719934.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2143 a         1393 c         1125 g         2155 t
ORIGIN      
        1 tatatacaat attttcggaa cattcaactt tttaactcta tttattacta gatttcataa
       61 ttaaaaagcc tactgaccaa gctagaaagc ttgatacaat aggcttttta aagactgatt
      121 atttaacagc gtctttaaga gctttaccag ctttgaatgc tggtacttta gaagctgcaa
      181 ttgtcatttc tttaccagtt tgtgggttgc gacctttacg ttctgcgcgc tcacgaactt
      241 caaagttacc aaaaccgatc aactgaactt tttcaccagc tgcaagatag tcagctactg
      301 ctgcaaatac agcttcaact gctgctgctg agtctttctt agtcaattct gtagcttctg
      361 ctactttagc gatcaaatct tgtttgtttg ccatgttaat gattcctcca aataatttct
      421 aattaacaaa tataatcata tcctaaaatc ccttttaggt caagttaaaa acgctatttc
      481 ttcccatttt atttattttt ttaggagtgg taacgtatca aaatagccca agcgttctca
      541 cccgtgtgag tttgaataat ggaacccgtt tccaaaacag aaattggctt ttcaacataa
      601 gcttgtaagc tttctttcat ctcttttgcc caatcatcac taccagaata tgaaattcca
      661 atctctgcta cagcacgttc agaaagcgat gttatcaact catctaacca ttttttaaat
      721 gttttagttc cacgaccttt aaccattggc tgcaattcat ggtctttcat ttgcatgaca
      781 gcacggatat tgagaagaga gctcaacaag ccagttacac ggctaattcg tccacctttg
      841 acaagatttt ccaaagttga aacaccaata taaagctctg tatggttttt aacctcttct
      901 acatgagcta aaattgtctc catatcttta ccttcttgag ctaacttcgc agcctcaaca
      961 acttggaatt tcagggcttg gtcagtgaag gaactatcaa caacagtcac atctgcagta
     1021 gataggctag caccttggcg tgctgcttct accgtacccg aaagagcatg ggacatatga
     1081 atagcaagaa tctggccacc atctttgcat aggtcttcaa aaatctcagc aaagacacct
     1141 acaggtggct gacttgtttt cggaagattc ttactttctt gcatcaactg aagaaattta
     1201 ccttcttctt tcaaatccgc atcagaataa acaacattat caatcattac agataatgga
     1261 acaattgtaa tatctaattg ctttactagt tcaggttcaa tagtaacaga tgaatcggtt
     1321 acaatcttaa tttttgtcat agtatcaatc tttctatttt aggattcaga ttggtttcct
     1381 tacttctaat tatatcaaaa aaaagattaa aaatcctaat ggagtcaatc aaattttccg
     1441 taaaatttga tataatcaac ttataagaaa agaggtgtcc tatgattaaa aaaatttacc
     1501 ccatttttac cattttacta ggtgctgcta tttatgcttt tggactgact tattttgtag
     1561 ttccccatca tctctttgaa ggaggggcga caggcattac cctcatcacc ttttatcttt
     1621 ttaaaatccc tgtttccctc atgaacctgc tgattaatat tccccttttc atcctagctt
     1681 ggaagatctt tggagccaaa tccctctatt ctagtttact aggaacctta gctttgtccg
     1741 cctggttagc tttttttgag catattcccc ttcatattga tcttcaaggt gatttactaa
     1801 tcacagccct tatagcggga atcctattgg gaattggcct tggaattatt tttaatgctg
     1861 gaggtacaac tggcggaact gatattctag ctcgtattct caacaaatac actcatatat
     1921 ccataggaaa actgctcttt atcttagatt tttgtattct catgttgatt ctcctaatct
     1981 tcaaggattt gagattggtt tcctacacgc ttttgtttga ttttattgtt tctcgtgtta
     2041 ttgatttgat tggtgaagga ggatatgccg gcaaaggctt tatgattatc acaaaacgtc
     2101 ctgaccaact tgctaaggcg attaatgatg acctcggaag aggtgttact tttatttctg
     2161 gtcaaggcta ctatagtaaa gaaaatttga aaatcatcta ctgtattgtc ggaagaaatg
     2221 aaattgtgaa aacgaaggaa atgattcatc gaatcgatcc tcaagccttt ataactatta
     2281 cagaagccca tgaaatccta ggagaaggct tcacctttga aaaagaataa aaagaggtaa
     2341 tgtcgtgacc tcaaaagtta gactaaatca tctatctttt gggttacaga caacctcttt
     2401 tttgttttat ttactcaagc tcttaagacc aattccgagt tacttcttca tcagccttta
     2461 actgttccac taattggtca actgagtcaa atttggtcat atcacgaatg cgatcaagcc
     2521 aataaaccat gacggtttcc ccataaatat cttgattaaa atcaaaaata ttgacttcaa
     2581 aacgtgcttc ttctccatca aaggtcacat ttttcccgac actagccata gcacgatact
     2641 tctgtctttg aatctcaaca tcaacgacat aaacgccatc tgctggcata taagtacggt
     2701 ctaaaagcac taaattcgct gtcggataac caattgtacg accacgagca ttaccatgaa
     2761 ccaccatacc tcttgatgga agcggtgccc ccaaaagttt tcctgcttct ttcacatttc
     2821 catctaaaat agcttgacgg atacgagttg aactaatctt tcctttctca tcttctacag
     2881 gtggaacaat gataacttct ccatcaaagt aatcctttaa atcttctgct gtttttttgt
     2941 cagaaccaaa tgtataatca aaacctgcaa caataatttt ggcattcata gccttgatat
     3001 aagttgcaaa gaattcttgt gcagtgagac tagcgaattg actactaaaa tcaaggagat
     3061 ataattcttc tacaccttcg cgctttaatt ttctttcacg ttcagcaggg ttcaaaatat
     3121 gcaaaaacaa atctggatga taaggctcta aagcgatctt tggagattca ttaaaggtca
     3181 taacgacgat aggtaataaa tcctttctcg cagccttgtt ggcaacacga aataattctt
     3241 gatgcccctt atgtatgcca tcaaaatagc cgagaacaac gactgaatca gatggtgtgc
     3301 caatatcttt ttggtttttt ataggaatag taataatcat aaaataatta tatcatagcg
     3361 atagctattt ctggaacaga aaatctgaaa tgttgttttt ttcacatgaa gtgtactgtt
     3421 ttcaaaaagc actttattct atcgttgctt aactatgaac tttgcaatat tcttctcaaa
     3481 aacttgtagg acatcttcaa aattttgcaa ggagtgatta gacttgttcg gtaaccataa
     3541 agtgtcatac tatgcttatg tatgaaaaag caatgcaact aactcctgag aactttaaat
     3601 tactaattgg tgccgaaaag gtagaattta gaatcgaggt acacctatgg ctgtaaaatt
     3661 tacaaaatga gacaacttgg gcaagatgtt tgaagaattt cctaaactcc ctgatttgaa
     3721 gcaagtcact ttccctgatg acaaagaaaa aagccaaaac agcaaagaaa aactagatga
     3781 ctgctttcca acaactccca tctagtgtgc ttcagactag gctatttttc tctccatctg
     3841 ttagcttgga ttctcagacc gtttcagcta aagaatatct tttcccttat cagaaggaac
     3901 ggctcaaacc attcagacaa gtgaagggac gacaagccaa tatttgaaac cagatagcag
     3961 ttcttatagt caattgaaat aaaatctgaa gaaatcgagt aggaaactca tatcaatttt
     4021 taacagtgtt ctattccaga ttcaatccac tatacatatt aaaaagtatg ggtaccaaaa
     4081 caaaaaaaca ggctctccga aaactcggaa agccttattt taagctgttt ctagcttcct
     4141 cacctttaca tttcaaggtt cgggataaaa ggttcaatgg acctttttat ttagcgattg
     4201 ggtaaacaga aacttgtttt ttatcgcgtc ctttacgttc aaagcgtact acgccttcaa
     4261 ctttagcgaa caaagtatcg tctccaccac gaccaacgtt tacacctgga tagatgtgtg
     4321 taccacgttg acggtaaagg attgatccac ctgttacagt ttgtccgtca gctgctttag
     4381 ctccaagacg ttttgcttgt gaatcacgtc cgtttgatgt agaacctcca ccttttttgt
     4441 gggcgaaaag ttgcaagttg ttaagagtca tttttaacat aatgttttcc tccgtgttag
     4501 ttttctgtga taactctggt ttggacgaac tcagaatagt tctccgataa gtttgccata
     4561 cctaagaaaa atgattcaaa gaataactgg gtcatttctc tctggtgtga aggaagatct
     4621 tttggtattt caaccatcag atagccacct tcatcttcgt ttaattctag gattggttca
     4681 tagcctgcaa atttctcaat agaattgata aagttaatgg caagcgtaga aaccgatgca
     4741 cacacgacat ctaagccgta ttcgccactc tcggcgtgtc cagtaatttc cgcactcctc
     4801 agctcaccat cttcggctct ctcaaagact gcctgtatca tgtgttctcc ttaaaattaa
     4861 gcgttgattg cgttgatgac aacttttgta tatggttgac ggtgaccttg tttacggtgg
     4921 ctaccttttt taggtttgta cttgtaagta accactttct tttgttttcc ttgtttttca
     4981 acagttccaa ctacagtagc tccagcaaca agtggagttc cgacaacagt gttttcacca
     5041 ccaacaagaa caacttcgtt aaaagtaact tcttgaccag cttcaacgtt caatttttca
     5101 acgtaaactg cttgaccaac ttcaacttta acttgttttc cgccagtttt gataattgcg
     5161 tatgtgctca ttatgcacct cctatgattt ttatgggttt ccccgatttt ttgtgaagac
     5221 tcgcctagca tcgtgggacg aaccacttaa acttgaataa tcaagcaacg atgttcgtgc
     5281 ggttgcacag gatcgtgcat agtcaactct tcaagtatag catatctcct attttcttac
     5341 aagtaataac acctaaaatg aagctttttc ttttactttt ttctgccaag aggcaaaaag
     5401 catgctgagg taaaaaacgc tcatcataat aggaacacca agaatggtct tttcatgata
     5461 gaaaatcgtc aaataggctg aaaagacaac gccaaggaca aaactactaa gcaggctaac
     5521 aaatatgaat ccttcacgca aaaaaggagt gtgcttggtt cggaaataat ctccaaaagc
     5581 cagcatggtc cgtttgatat tccctgtcat aaaagcgtta ttataggcaa tacccgacac
     5641 ttctccaaaa gcagttgtca ccagtcccat acagaaggcc aagggcggca ctagatagat
     5701 attatccaca gtttgcggca caaaagcaat aatgattgat aagattgcca agggaatcaa
     5761 ggacagaata ggttttttca caattctcaa tttttcctta taaatcgtta ataaaaagac
     5821 tcccatcata aacgctagca aggtgagaac cttgtcccta acatccgaaa cattattttt
     5881 aattaattct actgaaagaa agacaacatt tccagtttgt ccagctacaa gggtattccc
     5941 gcgaacaata aaagtgtaag catccacata tccagcacaa aacgtcaaaa aaagtgctaa
     6001 ccttttagac tgacgtgata tttttcttat aggtaataac ctcattttac ctcccattgt
     6061 attttctctt agaaatattg taccattttc tttctaaaaa atcgtaggct accatttaga
     6121 ttttactatt agcataaaaa taataataga caactattta tccaaaaata gatagatgta
     6181 acatgtttgc aaacaaagca tacgaacctt tagtaaaatc atttccatga aactagaata
     6241 gagccctctt agcaaaaatc attattttaa tttatttcta atcactcctt gacataaata
     6301 actctcacca ataaaagact atgtcttaaa aaaatggtat aataaaatca atacttgggc
     6361 ttgatggcta tgctactaat aacaattagg agagaaaatc aggcacttgt taacaacaag
     6421 gattatcccc ttgagatgaa aggaacttta gaaatcttat gatgaacatg caaaacatga
     6481 tgcgtcaagc acaaaaactt caaaaacaaa tggaacaaag ccaagctgaa cttgctgcta
     6541 tgcaatttgt tggcaaatct gctcaagatc ttgtccaagc gaccttaact ggcgataaga
     6601 aagttgtcag cattgatttc aatccagctg tcgttgaccc agaggacctt gagactcttt
     6661 ctgatatgac cgttcaagcc atcaactctg ctcttgaaca aatcgatgaa actaccaaga
     6721 aaaaactggg tgctttcgct gggaaattac ctttctaaaa acaaggagct agaacaatgc
     6781 ttgtcgataa caaaggctaa gaaaggtgca aaaatg
//
LOCUS       DAVLZS010000075         6389 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLZS010000075 DAVLZS010000000
VERSION     DAVLZS010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.075"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(109..186)
                     /locus_tag="VYO88_001894"
                     /pseudo
     CDS             complement(109..186)
                     /locus_tag="VYO88_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            257..913
                     /locus_tag="VYO88_001895"
     CDS             257..913
                     /locus_tag="VYO88_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1719935.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            903..1226
                     /locus_tag="VYO88_001896"
     CDS             903..1226
                     /locus_tag="VYO88_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV1719936.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1330..2160
                     /locus_tag="VYO88_001897"
     CDS             1330..2160
                     /locus_tag="VYO88_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1719937.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2314..3168
                     /locus_tag="VYO88_001898"
     CDS             2314..3168
                     /locus_tag="VYO88_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1719938.1"
                     /translation="MKIKKWLGLVALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3268..4641
                     /locus_tag="VYO88_001899"
     CDS             3268..4641
                     /locus_tag="VYO88_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1719939.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4634..5695
                     /locus_tag="VYO88_001900"
     CDS             4634..5695
                     /locus_tag="VYO88_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1719940.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5697..6389
                     /locus_tag="VYO88_001901"
     CDS             5697..6389
                     /locus_tag="VYO88_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1719941.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
BASE COUNT         1825 a         1250 c         1500 g         1814 t
ORIGIN      
        1 gtgttttgag ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagctgac
       61 ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcat cagttctatc
      121 tgcaacctca aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat
      181 tttcattgag tattattaag acaatatgag gagaaagatg aaagaaaaag gattttagga
      241 gggggcgcag gcagccatgc caacggctct tggctatgtc agtatcggct tggcctgtgg
      301 gactatcggt gcgccctatg tgacacctgt tgagatgggc ttgatgagtc tctttgttta
      361 tgctgggagt gcccagtttg ccatgttggc actgattgtg gttcaagctc ctgtggcagc
      421 tattgctatg acggtttttc taatcaactt gcgtctcttt ttgttgagtt tacacgcatc
      481 gacttatttc cgtcatacca gtctttggta caatatcggt atgtctagta tcttgacaga
      541 tgagacctat ggcgttttga tgggtgaatt ggcccataca gacaaggtaa atcctatgtg
      601 gatgcacgga aacaatctta acagctatgt ggcttggttt gtggggacag tagtcggaac
      661 ggctctgggt ggcctgctac caaatccaga aatctttggc ttggattttg ccctggttgg
      721 gatgtttatt ggtatttttg cttcgcaatt tcagattatg caaagacgga ttcctgtccg
      781 caatctgctc attatcctag cagttgttgc ggtgtccttc tttttgctct tgacagtggt
      841 gtctcagtca ctagctgttc tgtttgcgac gctacttggt tgtagcatgg gggtggtttt
      901 agatggtcag taagtatctt ttattagcag ttattttctc tggcttggtg acttggattc
      961 tccgtatgat tcccttcatc ttagtcaagt ataagggctt gcctgcaatc gttgagcgtt
     1021 ttttgaagtt cttgcccgtt tccattatct ttgccttgat tctttcaagc gtagtgacag
     1081 gtaaggttgg gagccttcct caaattaaat ggctagactt cttagccgtc tttccaacag
     1141 cttgggtagc ctttcgctac cgcaatctag tcggaacagt tctctttgga gtggtcttga
     1201 ttgccatctt gcgtttggtc ttttaaatta cccataaaaa aaacttatca cagagataga
     1261 tatcatataa tggcgtaaat gctctttttc tgttaagatt ataaggtatt ctattttgga
     1321 ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg ctgccctagg acttgttgct
     1381 gcaggtgtgc ttgcggcttg ctcagggggt gctaagaaag aaggagaagc agctagcaag
     1441 aaagaaatca tcgttgcaac caatggatca ccaaggccat ttatctatga agaaaatggc
     1501 gaattgactg gttacgagat tgaagtcgtt cgcgctatct ttaaagattc tgacaaatat
     1561 gatgtcaagt ttgaaaagac agaatggtca ggtgtctttg ctggtcttga cgctgaccgt
     1621 tacaatatgg ctgtcaacaa tcttagctac actaaagaac gtgcggagaa atacctctat
     1681 gccgcaccaa ttgcccaaaa tcctaatgtc cttgtcgtga agaaagatga ctctagtatc
     1741 aagtctctcg atgatatcgg tggaaaatcg acggaagtcg ttcaagccac tacatcagct
     1801 aagcagttag aagcatacaa cgctgaacac acggacaacc caactatcct taactatact
     1861 aaggcagatt tccaacaaat catggtacgt ttgagcgatg gacaatttga ctataagatt
     1921 tttgataaaa tcggtgttga aacagttatc aagaaccaag gtttggacaa cttgaaagtt
     1981 atcgaacttc caagcgacca acaaccgtac gtttacccac ttcttgctca aggtcaagat
     2041 gagttgaaat catttgtaga caaacgcatt aaagaactct acaaagacgg aacgcttgaa
     2101 aaattgtcta aacaattctt cggagatact tatctaccag cagaggctga tattaaataa
     2161 tttcttgaaa tcatccattc tgagtaagat gggtgatttc tcagttttta gggatatagt
     2221 tttaaactat atatctgatt atctaataac aatttgtgaa atcaaacaaa ttgtgagata
     2281 ctagtacggt attattttta aggagaaaga atcatgaaaa tcaaaaaatg gcttggccta
     2341 gtagcccttg ctacagtcgc aggtttggct cttgcagctt gcggaaactc agaaaagaaa
     2401 gcagacaatg caacaactat caaaatcgca actgttaacc gtagcggttc tgaagaaaaa
     2461 cgttgggaca aaatccaaga attggttaaa aaagacggaa ttaccttgga atttacagag
     2521 ttcacagact actcacaacc aaacaaagca actgctgatg gcgaagtaga tttgaacgct
     2581 ttccaacact ataacttctt gaacaactgg aacaaagaaa acggaaaaga ccttgtagcg
     2641 attgcagata cttacatctc tccaatccgc ctttactcag gtttgaatgg aagtgccaac
     2701 aagtacacta aagtagaaga catcccagca aacggagaaa tcgctgtacc gaatgacgct
     2761 acaaacgaaa gccgtgcgct ttacttgctt caatcagctg gcttgattaa attggatgtt
     2821 tctggaactg ctcttgcaac agttgccaac atcaaagaaa atccaaagaa cttgaaaatc
     2881 actgaattgg acgctagcca aacagctcgt tcattgtcat cagttgacgc tgccgttgta
     2941 aacaatacct tcgttacaga agcaaaattg gactacaaga aagcactttt caaagaacaa
     3001 gctgatgaaa actcaaaaca atggtacaac atcattgttg cgaaaaaaga ttgggaaaca
     3061 tcacctaagg ctgatgctat aaagaaagta atcgcagctt accacacaga tgacgtgaaa
     3121 aaagttatcg aagaatcatc agacggtttg gatcaaccag tttggtaata agaaacaggg
     3181 aggtgggaga gagaattcca cctcttgctt ttgtatagag cacggagtgt aaagaagact
     3241 attcgttcat agaaaggtag agagaatatg gtttttccta gcgaacaaga acagattgaa
     3301 aaatttgaaa aggatcatgt agcccagcat tattttgagg ttttgcgtac cttgatttct
     3361 aagaaatcag tctttgccca gcaggttgga ctcaaggaag tcgcaaatta tctgggtgag
     3421 attttcaagc gtgttggagc tgaagtggag attgatgaga gctatacagc gccctttgtc
     3481 atggcacatt tcaagagttc gcgtccagat gccaagacct tgattttcta taaccactat
     3541 gacactgtgc cagcggatgg ggatcaggtc tggacagagg atccttttac gctttcggtc
     3601 cgcaatggct tcatgtatgg gcgtggagtt gatgacgaca agggtcatat cacagctcgc
     3661 ttgagtgctt tgagaaaata tatgcagcac catgatgatt tacctgtcaa tatcagcttt
     3721 atcatggagg gagcggagga atcggcttca acagacctag ataagtattt ggaaaagcat
     3781 gcagacaaac tccgtggggc ggatttgttg gtctgggaac aagggaccaa aaatgccttg
     3841 gaacagctgg aaatttctgg tggcaataag gggattgtga cctttgatgc caaggtaaaa
     3901 agcgctgatg tggatatcca ctcgagttat ggtggtgttg tggaatcagc tccttggtat
     3961 ctcctccaag ccttacagtc tcttcgtgct gcggatggcc gtatcttggt tgaaggcttg
     4021 tacgaagaag tacaagagcc caatgaacga gaaatggcct tgctagaaac ttatggtcaa
     4081 cgaaacccag aggaagttag tcggatttat ggattggagt tgcctctctt acaggaggag
     4141 cggatggcct ttctaaaacg tttctttttc gagccagcgc ttaatatcga aggaatccag
     4201 tctggttatc aaggtcaggg tgttaagact attttacctg cagaagccag tgccaagcta
     4261 gaggttcgtc tggttccggg cctagaaccg catgatgttc tggaaaaaat tcggaaacag
     4321 ctagacaaaa atggctttga taaggtagaa ttatactata ccttgggaga gatgagctat
     4381 cgaagcgata tgagcgcacc agccattctc aatgtgatcg agttggccaa gaaattctat
     4441 ccacagggcg tttcagtctt gccgacgaca gcggggacag gacctatgca tacggtcttt
     4501 gatgccctag aggtaccaat ggttgcattc ggtctaggaa atgccaatag ccgagaccac
     4561 ggtggagatg aaaatgtgcg aatcgctgat tattacaccc atatcgaatt agtagaggag
     4621 ctgattagaa gctatgagta gagatattat caagttagat cagatcgatg tgacttttca
     4681 ccaaaagaag agaaccatca cagcggttaa ggatgtgacc attcacatcc aagaagggga
     4741 tatctacgga atcgttggat attctggagc agggaaatca acccttgtac gggtgattaa
     4801 tctcttgcaa aaaccatctg cagggaaaat taccattgac gacgatgtga tttttgatgg
     4861 taaggtcacc ttgacggcag agcagttgcg tcgtaaacgt caagatatcg ggatgatttt
     4921 ccagcatttt aacctgatga gccaaaagac agcagaggag aatgtagcct ttgcccttaa
     4981 acactctgga cttagcaagg aagaaaagaa ggctaaagta gctaagttgt tggacttggt
     5041 tggtttggca gatcgtgctg aaaactaccc ttcacaacta tctggagggc aaaaacagcg
     5101 tgtggcaatt gcgcgtgcct tggccaatga tccaaaaatc ttgatttcag acgagtcaac
     5161 ttctgccctt gaccctaaga caaccaagca gattttggcc ttgttgcaag atttgaacca
     5221 aaaattaggc ttgactgttg tcttgattac gcatgaaatg cagattgtca aagacattgc
     5281 caaccgtgtt gcagttatgc aggatgggca tttgattgaa gagggtagtg tgcttgaaat
     5341 cttctcagac cctaaacaac ctttgactca agactttatc tcaacagcta caggtattga
     5401 cgaagccatg gtcaaaatcg agaagcaaga aatcgtggaa cacttgtctg aaaacagtct
     5461 cttggtgcaa ctcaagtacg ctggagcttc aacagacgag ccacttttga atgaattgta
     5521 caagcattac caagtaatgg ctaatattct ctatgggaat atcgaaattc tcgatggtac
     5581 tcctgttgga gaattggtgg tggtcttgtc aggtgaaaaa gcagcgttgg caggtgccca
     5641 agaagccatt cgtcaagcag gtgtacaact aaaagtattg aagggagtac agtaagatgg
     5701 aatcattgat tcaaacctat ttaccaaatg tctataaaat gggttgggct ggtcaggcag
     5761 gctggggaac ggctatctac ttaactcttt atatgacagt tctttccttt atcatcggag
     5821 gcttcttggg gctagtggca ggtcttttcc ttgtcttgac agcgccaggt ggtgtcttgg
     5881 agaataaagt cgtattctgg attttagaca aaattacctc aatttttcgt gcggttccct
     5941 ttatcatcct cttggcaatc ttgtcaccac tttctcactt gattgttaaa acaagtatcg
     6001 ggccaaatgc agcccttgtc ccactttctt ttgcagtctt tgccttcttt gcccgtcagg
     6061 tgcaggttgt cttggctgaa ttggatggcg gtgtcattga ggcggctcaa gcgagcggag
     6121 cgactttctg ggacatcgtg ggtgtttacc tatcagaagg tcttccagat ttgatccgtg
     6181 tgacgactgt gaccttgatt tcccttgttg gggaaacagc tatggccggt gcggttggag
     6241 ctggtggtat cggtaacgta gccatcgctt atggatttaa ccgctacaat cacgatgtga
     6301 ccatcttggc aaccattatt atcattttga ttatctttgc aatccaattc ttgggagatt
     6361 tcttgactaa gaaattgagc cataaataa
//
LOCUS       DAVLZS010000076         6196 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLZS010000076 DAVLZS010000000
VERSION     DAVLZS010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6196
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.076"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..213
                     /locus_tag="VYO88_001902"
     CDS             <1..213
                     /locus_tag="VYO88_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719942.1"
                     /translation="NLYLRNYNEKNKYESMLKKILEVRPDFVLIEQNIDDSLNSSQPL
                     SLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            590..964
                     /locus_tag="VYO88_001903"
     CDS             590..964
                     /locus_tag="VYO88_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV1719943.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            1172..2074
                     /locus_tag="VYO88_001904"
     CDS             1172..2074
                     /locus_tag="VYO88_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719944.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISKNHNWSEKIDKIRIELIKINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            2130..2483
                     /locus_tag="VYO88_001905"
     CDS             2130..2483
                     /locus_tag="VYO88_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1719945.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            2480..3208
                     /locus_tag="VYO88_001906"
     CDS             2480..3208
                     /locus_tag="VYO88_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719946.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            4339..4578
                     /locus_tag="VYO88_001907"
     CDS             4339..4578
                     /locus_tag="VYO88_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719947.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            4563..4841
                     /locus_tag="VYO88_001908"
     CDS             4563..4841
                     /locus_tag="VYO88_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719948.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            5127..>6196
                     /locus_tag="VYO88_001909"
     CDS             5127..>6196
                     /locus_tag="VYO88_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV1719949.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKSEAAKKHYEEVKAKFEAAKKEYEDGKAAQKKYEDDQKKTEEKAEEERKAS
                     EEEQAANLKYQQAVLKYIKETDPQKRVEAQKVMDEAQKEHTRTKEKFDEVRAKVIPSE
                     EELKKTRQKAEEAKLKEAEVAKKVEETKKQEEEAKAKLEEAEKKATEAKQKVDAEEVA
                     PQAKIAELENQVHRLEQELKEIDESDSEDYIKEGFRAPLQSELDTKKAKLLKLEELSG
                     KIEELDAEIAELEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAEADLKKAVDEP
                     ETPAPAPAPAPAPAPAPAPAPAP"
BASE COUNT         2164 a          824 c         1175 g         2033 t
ORIGIN      
        1 aatctatatt tacggaatta taatgaaaaa aataaatatg aatcaatgtt aaagaaaatt
       61 ttagaggtaa gaccagactt tgttttaatc gagcagaata ttgatgatag tttaaatagc
      121 tcgcaaccat tatctttatc tttagccatt tcagaaatcc aacttttgct tgaagtgtat
      181 atagggatca aacatgtttc aattaggaga taaaactaga ataatatttg ccattatagg
      241 ggcaagttgc atattagtca gtatgtatct tattccactt attaaaactg agaataaatt
      301 ttgggaaata cttttattta tattaggtgt attgctaatt ggaattgcgt tactaagtca
      361 aaaaaaataa attttgaaat agtattagtg agttcgcaat catttattgc tagtggttta
      421 gaactgttaa gtttcaaaca ataattgatt ttaaacctta ggtaacctat aaaaacaaat
      481 aaggtagaga aaggatatct tatctaggta gctaagtgat aaaaacacag tcgtctatca
      541 cttgttagga aactatccta actatgctta ataaaaaagg agaaaataaa tggaactcgt
      601 attaccaaat aattatgttg ttcttgagca agaagagatg atgtatcttg atgggggatt
      661 ttctattctg agatggcctg ttgcaacagc cattaatata gcttttaatg gtgttttagg
      721 tggaggagca atcagtctag ttagaaatta tattcgtaat tatggtttgc ggcgagttac
      781 aagcgcaatt gctggagcag ctgcaagata tgttggggta cgagttgcaa atagagtggc
      841 aggatttgca ctgtctgcta ttaatggatt tgcagcttgg atgtcaattg gcgatgctat
      901 tacaacaatc tgggccaata atgatgtaaa taggagagac ccaaatttaa acgccttgtg
      961 gtaactagat atgggtatta aaatggaaaa aatttttgtt attatttttt ttgtatgtct
     1021 atttatatca tccataactt ttttagccta tgattttgtt agcgaagaaa taaaaaagtt
     1081 gattatttgg attaatgtcg tttttttgat tttaatcata gcaatgatga tttatccaaa
     1141 attaagaaaa tgataaggac actgtaaaat tatgatacgt aaactaattg ttttcttact
     1201 aatgctccct ctttttgtct tgtggctaga gttgcatgtc ctagtgaata acttactatt
     1261 gaatctagaa tctccccttg attttgtgat tagtatgagt cttgctttct gtagtttgat
     1321 tttatcaaaa atagttttag acatactata cgcattgaaa gatttgtaca agaaagaagc
     1381 tcttattacg atttttcctt ttatttttat aggcaggaag aaagtaaatg tgaggttctc
     1441 gccctatttt tcattccatc gtaaaagttt gtcgcctgat gatttaagat ctaggattat
     1501 atggagtttt attcttgaaa ttgctattat cctagtattt attttaaaaa ttccttttgc
     1561 aatcatcatg cttactacaa tatttttctg gactataatg gatatcaatc atctcgtttt
     1621 taataagacg gaatttcttt ttaatcaaaa caaatggcaa aaagaagatt cgtttgaaag
     1681 tgatttgacg aaaacgttaa aggataagat acaaaaatca gaattaagct attctgactt
     1741 aatgtccctt cttctctatg atgcgatgaa ccaatccacc tttttaacgg atagtgaact
     1801 ttttgaggat attttgaaaa aaatcgaaga ttctcataac acccttctgt gtacaggtct
     1861 tgtcgagtta ctgctgtatg aaatttctat tagtaagaat cataattggt cagaaaagat
     1921 tgataaaatt aggatagagc ttatcaagat taatcaatta gattttttct attatacaag
     1981 ttggttaagg caaaattttg atttctgtat gaatagagag tatcataaaa tgaaatctcg
     2041 gaaattatta ctgagtaata aaaagatagt ttaagttcgt cctatttgta aaacaaatga
     2101 aacaatttca actaaggagg agaaaacaaa tggaacttgt attaccaaat aattatgttg
     2161 tgattgatga agaagtaatg atgtatcttg atgggggagc ttatttaagc aagcgtgctt
     2221 gtcaaggaat ttgcgcagct ttagctatga gttcaggaac ttttatagca ttagctggag
     2281 ctgcagtttt aaccaaaaaa ctaataaact atattaagtt tggaggtctt ggaggctggc
     2341 ttattggtgc agcagcaggt gtattggcta cagcagcagg gaaaatagct tactatattg
     2401 gatatggtgt tcttaataga ggttgtgata ttaacgggaa cccttatcct tgggatggat
     2461 tcatatctgc aacagtaaga tgagtaatgt agataagatt cgaaaaatac atattatcgt
     2521 atgttggatg tatatatttt tatcattcag ggcgattata aatgacacgg agtatttttt
     2581 gcttattttt ttagctttta tctactcaat agtatcacta cctctatatt ctgtgaaaaa
     2641 taaaatagta tctatctgtc tagccataaa ttcgattctg ttaatgagtt tccccatttt
     2701 aatcaataag tttttcccag aaagtttttt gacttatacc gtattaataa gtgtttttat
     2761 cctagagtta gcaatctttc atttaattgg ggaagatttt gctactaaat tgactaacga
     2821 atataagaaa attagtcagt ttagaagcaa ggtgtctcaa tctccttgga taaaatattt
     2881 agagatttct agttttatat taactatatt tccatctatt ctttacggta cagttgataa
     2941 tcgtgtattg gctcttatct ttttgataaa aatttgtgta gataccacga taaaattttt
     3001 attcatcaga ttatttgaca caagtacttt aatgaagagg agaatatttt ttcttttcgc
     3061 attggatgtt atagcttact tatttttagg atatctttta gtgattcaaa aagcaggcta
     3121 tttgttttcg gttttacttc ttttttctaa tttttcagtt ccatttatca aagcaaagga
     3181 atacgaatta tttaaaaata gcaagtaata gaaacatagg ttaaatctta gaacggctta
     3241 aaatcagata tgataaaggg aaatagtctt atctaggtaa ctaagtgcta caaacacagt
     3301 cgaggatcac ttgttaggat tacattttaa tcatgcttaa taagaatgga gaattcctat
     3361 gggattgtat tactctgaag tttcgaatac cttagttctc gtgattttga gctgttctag
     3421 ctttagaatc cttcagaatg taaaatttta agcagtcaaa gacttagaat agcctgaaaa
     3481 catttatttt atagcaattc taggcttaga attgctcata tatatgtatt tgagctgctc
     3541 gatagttagg acagctctat tctgagaaat ctgagctatc aatgcttcag aatagtattt
     3601 cgcaaatggt ttttattgaa gaggtgattg ttttatgata gtctaaaata aaactgattt
     3661 aatggagtaa atggagaatc gtcacatgaa acattttttt gcaggaattg gtgagataaa
     3721 acttgttggc tacttattgt atatatgtgt aggactagcc cctctttttc atatatatgt
     3781 cataggttcg gaactgagtt ttgtgaaaat agtgttatct attttgggag ttatatttgt
     3841 aagtatgtta actattgctc gaatttatcg gacttttcta taaagaatag tttggacttg
     3901 aactgtatct aaaaacagag gttggtcgat tatcagcctc tttcttgtcg ttgaaaagag
     3961 tgagatatat tgacttttga aaaaaatgtc ataattgagt tgggataaac ctaaaagtaa
     4021 tatagtagat tgaatctgga atagtccgtt atgactgtta aaatatttct agaaattaat
     4081 ttgactttcc taatcgattt gttcacatct tgtttcaatc tactatactt tctcgttaaa
     4141 ccgttcggca attcatggtg acatggatac atagtagtaa gcacactatg tggcttggca
     4201 gagctaaaaa ctgttccctt gcgataagcc taataagcac aacataggga gttagagaag
     4261 ccgactctaa tcaaccactt tgggcagtag tgagaactgc cccgtgcttt ttattttgag
     4321 aaaatatgga gtttgtcgtt gaaattactt gattgtattt tggactatca agaaagattc
     4381 aatggaaaaa catgtcaagt atcaacgaat tataagtatt tagagatttt caaagtgaat
     4441 ttttgcttga ctgatttaca tcatttattt gacttataca aaatcacacg agattatgct
     4501 agtcaaacaa aacctgctat tcaagctggt gtttttattt tagaagattt tagaaatatc
     4561 ctatgtacaa tgatgtaatc gaaaggatat ctttatatga gtttatcggt gatattttct
     4621 attctaaaat aataagttgt tgcatcgtag ctagggattt atctaaaaat actatgaaat
     4681 tggacgtcat attttttgag gataaaaata aaagatccgc agttttaggt ttacgaagag
     4741 acaaaagcgg agtatttaaa ccagttactc tacattttac aagcgctaag aaatatgcta
     4801 aagttcgtaa aacagatgtg aaagaaatga aatggctata aagattgtcc gcaggcttaa
     4861 gcttgcgttt tttgttgttt aacgaaatta aaaaacaagc tctctcatcg gaaatgtttt
     4921 tataggaatg aaggaagatg atgctatgtt taaaaagaga atcgaaaagg gcaaaagtag
     4981 tgtctttatc tttttggagt agaagcttat gatatagaaa tttgtaataa aaatgtaata
     5041 taaaacattt gacaaatatt tacgggggga gtatacttaa tataagtata gtctaaaaat
     5101 gactatcaga aaagaggtaa atttagatga ataagaaaaa aatgatttta acaagcctag
     5161 ccagcgtcgc tatcttaggg gctggttttg ttgcgtctca gcctactttt gtaagagcag
     5221 aagaagctcc cgtagctagt cagtctaaag ctgagaaaga ctatgatgca gcagtgaaaa
     5281 aatctgaagc tgctaagaaa cattacgaag aagtaaaagc aaaatttgaa gctgctaaga
     5341 aggaatatga ggacggaaaa gctgctcaga aaaagtatga agatgatcag aagaaaactg
     5401 aggagaaagc ggaggaagaa agaaaagctt ctgaagaaga acaagctgca aatctgaaat
     5461 atcaacaagc ggtgcttaaa tatataaagg aaactgatcc ccaaaaaaga gttgaagctc
     5521 agaaagtaat ggacgaagct cagaaagagc atacaagaac aaaagaaaaa tttgacgaag
     5581 ttcgcgcaaa agtaattcct agcgaggaag aattaaaaaa gactagacaa aaagcagaag
     5641 aagctaaatt aaaagaagct gaagttgcta aaaaagtaga agaaacgaaa aaacaagaag
     5701 aagaagctaa agcaaaatta gaagaggctg agaaaaaagc tactgaagcc aaacaaaaag
     5761 tggatgctga agaagtcgct cctcaagcta aaatcgctga attggaaaat caagttcata
     5821 gactagaaca agagctcaaa gagattgatg aatctgattc agaagattat atcaaagaag
     5881 gtttccgtgc tcctcttcaa tctgaattgg ataccaaaaa agctaaacta ttgaaacttg
     5941 aagagttgag tggtaagatt gaagagttag acgctgaaat tgcagaactt gaagttcaac
     6001 ttaaagatgc tgaaggaaac aataatgtag aagcctactt taaagaaggt ttagagaaaa
     6061 ctactgctga gaaaaaagct gaattagaaa aagctgaagc tgaccttaag aaagcagttg
     6121 atgagccaga aactccagct ccggctccag ccccagctcc ggctccagcc ccagctccgg
     6181 ctccagctcc agctcc
//
LOCUS       DAVLZS010000077         6118 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLZS010000077 DAVLZS010000000
VERSION     DAVLZS010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.077"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(125..677)
                     /locus_tag="VYO88_001910"
                     /pseudo
     CDS             complement(125..677)
                     /locus_tag="VYO88_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(753..1529)
                     /locus_tag="VYO88_001911"
     CDS             complement(753..1529)
                     /locus_tag="VYO88_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1719950.1"
                     /translation="MFALLDNSVFLKRNKIWKKTLTYPVEREEITYKRKKAKGKRQAI
                     LAQFDSEEVHHRLENCICPDCQGELKEIGASLQRQELVFILAQLKRVNHIQHAYKCQT
                     CSKNNPSDKIVKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPI
                     TRKEIANWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTFLS
                     GKSEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(1453..1647)
                     /locus_tag="VYO88_001912"
     CDS             complement(1453..1647)
                     /locus_tag="VYO88_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1719951.1"
                     /translation="MKIIQQQSATIDSLTNELSLLREQVAYLTQKLSGKSSEKSVCPF
                     GQLSLFEEEQNMEEDSDLPS"
     gene            complement(1712..2062)
                     /gene="tnpB"
                     /locus_tag="VYO88_001913"
     CDS             complement(1712..2062)
                     /gene="tnpB"
                     /locus_tag="VYO88_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1719952.1"
                     /translation="MTIHLSSLGQVYLVCGKTGMRQGIDSLAYLVKTHFELDSFSGQV
                     FLFCGGRKDHFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(2043..2228)
                     /locus_tag="VYO88_001914"
     CDS             complement(2043..2228)
                     /locus_tag="VYO88_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719953.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(2637..3863)
                     /locus_tag="VYO88_001915"
     CDS             complement(2637..3863)
                     /locus_tag="VYO88_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1719954.1"
                     /translation="MAKTRYSGVFVDTKGKYFYETELGIDRISGKRIRKKSRKDSNGK
                     PFSTAREAYLELTRVKREYHKAHTYANYNMTVKQFILDCYIPYYKLYVEESTYAVRIK
                     NLEKIAERFYNKTLRGLTIEDIQNYRIWLLSSKDENGSGYSQAYASLIFGMFRKSLDY
                     AVEMGYLETNISKKAKAIPKGKAIVPYWTKVEFERVIAQICLDDFYEHLNFVMLWTFF
                     MTGIRVNEGMALWWNDIDFDKKRMRVHHMLILKSRKNWQRNAYTKTSDGKRIISLDDD
                     TISILKRWKDRQKEIGLGNETDFIFTYDSLPMIKSTLARIIQRYSELANVKRIQGKGL
                     RHSNASYLINEFNVSVLILSKRLGHSSPEITLKHYSHLWRGADESIAEIMSGNISIHT
                     APKTKIQFNGNQNLKR"
     gene            complement(3867..4061)
                     /locus_tag="VYO88_001916"
     CDS             complement(3867..4061)
                     /locus_tag="VYO88_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEV1719955.1"
                     /translation="MKPLISKDDLIKLGYKKHTAISIIQAVKQDLVYNKGIPFYNNRR
                     LGLVPRERVENLIGVKLDEE"
     gene            complement(4069..4881)
                     /locus_tag="VYO88_001917"
     CDS             complement(4069..4881)
                     /locus_tag="VYO88_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719956.1"
                     /translation="MTRELYNTKIIQYNSNTFEVIYYRKAKFRRLGETDTTVSNTSKS
                     PSEKELYQQANRIKRRIRHYMLCNDFDLFWTLTFNDEKINSHDYLIVKKKIRTWLKAQ
                     REKYGKFHYIFIPELHKNGRLHFHGVTGGFSPKLTKARNTKTGRLINKNGKQVYNVDS
                     YQLGFSTVTKIDSSEKVANYITKYITKDLLAIPSGYKQPKYFSSRGLIKPIVSYENLE
                     RNYFEGLTPSFSVGHLDNLEYKEDIAIYNLSIDDNEEIIQNSTDTRIKIRKE"
     gene            complement(4985..>6118)
                     /locus_tag="VYO88_001918"
     CDS             complement(4985..>6118)
                     /locus_tag="VYO88_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV1719957.1"
                     /translation="TYSPIWKYRFLSILRLATERLDLIQLPSNKIQIKTVEWKFYKEN
                     ERIIIELNPSGTIPNIQQVKEITRRLTEFLIQATNEDWNILESTVQNSYVVIKYGKSN
                     PRYTVSELFKITDEDYYINYKPIKLYDNICFDIASEANQQIIIAPSGAGKSLYLATLA
                     GLLIKQGHSISLIDAKQTSLGATFENLGIPVARNAEEIILLLEQMVFEMEDRYKRYFA
                     FSSVDFGTTYKHFSLPAHYLIFDEVLAALECGTSAQQKEMVRLLKILALKSRASGQGL
                     LVLASQKLLASDLPRAVTEQCQTRIILGNSSSISEETFYSVMGKEKIDLLAEYRGGVG
                     KGYILTPKTNGIKYFETPYFDLDSIDFKNKIRDFQTIPRKQIE"
BASE COUNT         1800 a         1172 c         1007 g         2139 t
ORIGIN      
        1 atagatattt ctcgctattt ataatggatt gaaataagat atgaacaaat cgattaggaa
       61 aggaaaattg atttatagaa atattttagc agtcgatgcg tactgttata gattcaacgc
      121 actataattg atgacgttta gctgtttcca acaaactcat aataatagct cttgctttag
      181 ctccttcaaa actttgagaa aataaccacc ctcgcttttt taaactgagc tcaggctaaa
      241 agagtccact ggactctttt actccgtccc ataaccaatg atttaatggc gcgttcagct
      301 agattattgg aaaggaccag atgtccgtct tttaaaatgg tcttaaaggt ttctttatac
      361 ttgaggctgt attcaattgc ccttcctagt tttgaacctg ctaaaactga ctgacggcgg
      421 caccaagcaa agaagtcttc cattaggggc tggagatgtt cttgacgttt ctgtagtcgt
      481 tcatcagctg gcaaagcctc ccagtctctt tccaaggaaa ataactgatc acaataagct
      541 aaacctttag ctcctaagga tgatttatct gcttgcttgg gggtcgcttc aaaaaatttc
      601 cttctcacat gcgcccaaca tccaacaagt gcagcttctt ccagttgacg ataagcttct
      661 agcggttcgc agtttaccaa gcttagcgtc gccttgctcc taaaccttgg actgctatcg
      721 cataggcaga actagaggac taaagtccta agttactgcc gcaacatatc acaatgaaca
      781 tagccagaat aatctcctag gaattcttgt actactgaac cacttcgaca ctgatcatgg
      841 tggtaaagcg taatcccttg tttctctgat ttacctgaca aaaaagtcca atagtaagtc
      901 agctgactat cactttctaa gacccgataa gaggtttcat ctgcatgaag aagaggttgt
      961 tctaacaact tttctcgtaa aaggttataa agggactcta aatagtattg actcgccttg
     1021 atatgccaat tagcaatttc cttacgtgtg attggtaaac ccatcctagc ccaatcttct
     1081 tcttggcgat aattaggtac cttcagatta aacttctgat ggatggtgtg agcgataata
     1141 gaagctgagc caaggctatg cgccaaaggg gctttaggaa taggagcttt cacgatttta
     1201 tcacttggat tattcttact gcatgtttgg catttgtaag cgtgttggat atgattcact
     1261 ctttttaatt gcgcaagaat aaagaccaat tcttgtcgtt gaaggctcgc tccaatctct
     1321 tttagctctc cctgacagtc agggcaaatg cagttctcta agcgatgatg aacttcttct
     1381 gaatcaaatt gggcaagaat agcttgacgt ttccctttag ctttcttacg tttataggtg
     1441 atttcttctc tttcaactgg gtaagtcaga gtcttcttcc atattttgtt cctcttcaaa
     1501 aagactgagt tgtccaaaag ggcaaacact tttctcagag gattttccag agagcttttg
     1561 cgttagataa gccacttgtt cacgcagaag ggaaagttca ttagtgagac tatcaattgt
     1621 agcactctgt tgttgaatga ttttcaatct tcttccatga gcttccctct ctgttttcta
     1681 actttattat actaaaaaga aagtcctcat ttcaatagaa atcacgactt tctgataaat
     1741 ttattttggg agtgatagaa aagcccttca taagccagtc tacttgttca ggtgtgagag
     1801 ctttgacatc cttttctgta ctgggccaag tcagtctgcc gttctcaaag cgtttatata
     1861 atagccaaaa tccttgacca tcccagtaaa gggctttaaa gtggtcttta cgtccaccac
     1921 aaaagagaaa aacttgacct gagaaagaat ccaattcaaa gtgggtttta accagataag
     1981 ccagtgaatc gattccttgt ctcatacccg ttttcccaca tacgagatag acctgcccta
     2041 ggctagatag atgaattgtc atagagcaac accttatcca aaagctgttc tatcatttcg
     2101 agattgagag attgaaaaaa acttacttca agcttgccaa tacgaatttt aagcagaata
     2161 tcatttctct ttttagaatc aaaacgacga gattgtggaa tctctacagg aacaataggt
     2221 tgtggcatta aaatatcctc caatagtttt actttactaa tagtatacag gaggagctcc
     2281 atgaatgata gataccttgt tatgacgcgc ttaccatatt agaaagttgg ctctctaatt
     2341 aaattaattc tcattatata tatcaaaaga ccgcagcttg aaaactacgg tctaattttt
     2401 tgtccaaatg taaaccactt ggaactatta ttcaatttat tctttttaat aaatgttccc
     2461 gttttaatcc cagttacagt ttttaatcct ctgtaaccgt tgattttaca aagcttttaa
     2521 tttttttgcg attactccca ctcaattaac aatttcatag gtttagtgcc agaaaacctt
     2581 gatttattaa ggtttacaat gccttttaaa tatatttggc gggatttctg gcggggttat
     2641 ctttttaggt tttgattccc gttgaattga atttttgttt ttggagctgt atgtatggat
     2701 atattcccac tcattatttc agcaatagat tcgtcagctc cgcgccaaag gtgtgagtaa
     2761 tgtttcaaag taatttctgg gctagaatga cctaaccttt tcgacaaaat taagacagat
     2821 acattaaact cgtttatcaa ataagaagcg ttactatgac gaagtccttt accctgtatt
     2881 cgctttacat tagctagttc agaatatcgt tgaataattc tagctagtgt agattttatc
     2941 attggaaggc tatcatatgt aaatataaaa tcagtttcat tgcctaaacc aatttctttc
     3001 tgtctgtctt tccaacgctt taaaatagaa atcgtatcat catctaggga aataatacgt
     3061 ttgccatcac ttgttttggt ataggcattt ctttgccagt ttttccttga ttttagaata
     3121 agcatatgat gaacacgcat acgcttttta tcaaaatcaa tatcattcca ccaaagtgcc
     3181 attccttcat ttactcgaat acctgtcatg aaaaaagtcc aaagcataac gaaattaaga
     3241 tgttcataaa aatcatcaag acagatttga gcaataacac gctcaaattc tactttagtc
     3301 cagtatggaa cgatagcctt tcctttcgga atagctttgg ctttcttaga gatattagtt
     3361 tccaaataac ccatttctac agcataatca agagactttc taaacatacc aaagattaga
     3421 ctagcgtagg cttgagagta gccagaaccg ttttcgtctt tgcttgacag taaccatatc
     3481 cgatagtttt gaatatcttc aatagtcaaa ccacgtagtg tcttgttata aaatcgttca
     3541 gcaatctttt caagattttt gattctgaca gcataagtac tttcttccac atacaattta
     3601 taatatggta tataacaatc taaaataaac tgcttgacag tcatattgta attagcgtaa
     3661 gtatgagctt tgtgatactc tcgttttacc cgagtcaatt ctaaatacgc ctctctggca
     3721 gtagaaaaag gcttaccgtt gctatctttt ctacttttct ttctaatacg tttaccactg
     3781 attctatcaa tgcctagctc tgtttcatag aaatattttc ctttcgtatc aacaaacaca
     3841 ccgctataac gtgtttttgc catttgttat tcctcatcta gttttacacc gataaggttt
     3901 tctacccttt cccgtgggac tagtccaagt ctacggttat tgtagaatgg tataccttta
     3961 ttatacacca aatcctgctt taccgcttga ataatactaa ttgcagtatg tttcttatat
     4021 cctagtttta tcaagtcgtc tttactaatc aatggtttca tacgcttact attcctttct
     4081 gatttttatt cttgtatcag ttgaattttg aataatctcc tcattgtcat ctattgatag
     4141 attgtaaatc gcaatatctt ctttgtactc aagattatct aaatgaccta ctgaaaaact
     4201 gggggttaat ccctcaaaat aatttctttc taaattttca tagcttacta tcggttttat
     4261 taaaccacga gatgaaaaat attttggctg tttatatcca cttggaatag ctagtaaatc
     4321 ttttgtgata tattttgtaa tgtagttagc aactttttca gaagaatcga tttttgtaac
     4381 agtactaaat cctaattgat atgaatcaac attatagact tgcttgccat tcttatttat
     4441 caatcgacca gttttagtat ttcttgcttt tgttaatttt ggactaaaac cgcctgttac
     4501 tccatgaaaa tgaagccgtc catttttatg taattctggt atgaaaatgt agtgaaattt
     4561 tccatatttt tcacgctgag ctttgagcca agtgcgtatt ttctttttta cgattaaata
     4621 atcatgggaa ttgatttttt cgtcgttaaa agttaatgtc caaaataaat cgaaatcatt
     4681 gcacagcatg tagtgacgaa tacgcctttt tatcctattg gcttgctgat agagttcttt
     4741 ttcacttgga cttttagaag tattagatac tgtagtatcg gtttctccta gtcttctaaa
     4801 ttttgctttt cgatagtata tgacctcgaa agtatttgaa ttatattgaa ttatttttgt
     4861 gttatataat tctctagtca ttagtcctcc gcttatcatg cctgcatgtc aagtagcagg
     4921 ctaatataca catctagcga gtcctggctt gcttatgagc aagccggctc actagatagt
     4981 tagttcattc tatctgcttt cttggaatag tttgaaagtc ccttatttta tttttgaaat
     5041 ctattgaatc taaatcaaaa tacggagtct caaaatattt tattccgttt gttttaggag
     5101 ttaaaatata tccttttcca actcctcctc tgtactccgc caaaagatct attttctctt
     5161 tacccatgac actgtaaaac gtttcttcag atatactgga actattccct aaaataattc
     5221 tagtttggca ctgctctgtg actgcacgcg gtaaatcaga agcaaggagc ttttggcttg
     5281 caagaacaag caatccctgt ccagaagccc gtgattttaa ggcaagtatt tttagtagcc
     5341 taaccatttc tttttgttgc gctgatgttc cacattccaa agctgccagc acttcatcaa
     5401 aaattaaata atgtgcaggt aaagaaaaat gtttgtacgt ggtcccaaaa tcaactgaag
     5461 aaaatgcgaa atatcgctta tatctatctt ccatttcaaa taccatttgt tctagaagta
     5521 gaataatctc ttccgcatta cgtgcgacag gaatacctag attttcaaat gtcgcaccta
     5581 aagaggtttg tttagcgtca attaaactta tagaatgacc ttgtttaatt agtaacccag
     5641 ctagtgtggc tagataaagt gacttcccag caccactagg agctattata atctgctgat
     5701 tagcctcact agctatatca aaacaaatat tatcataaag ttttattggc ttataattga
     5761 tataataatc ttcatctgtt atcttgaata gttcactaac agtatatctt ggatttgatt
     5821 ttccatattt tataacaacg taactatttt gcacagttga ttccaagata ttccagtcct
     5881 cgttagtagc ttgaataaga aattcggtca accgccttgt tatttctttt acttgctgaa
     5941 tattaggaat tgtccctgaa ggattgagtt caattataat cctttcattt tctttataaa
     6001 atttccattc aactgttttt atctgtattt tattagaggg aagttgaatt aggtctaaac
     6061 gttctgttgc aagtctaaga atgcttaaaa atctgtactt ccatatagga gagtaagt
//
LOCUS       DAVLZS010000078         6056 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLZS010000078 DAVLZS010000000
VERSION     DAVLZS010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.078"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            97..339
                     /locus_tag="VYO88_001919"
     CDS             97..339
                     /locus_tag="VYO88_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1719958.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            341..595
                     /locus_tag="VYO88_001920"
     CDS             341..595
                     /locus_tag="VYO88_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1719959.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQINVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            642..1337
                     /locus_tag="VYO88_001921"
     CDS             642..1337
                     /locus_tag="VYO88_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEV1719960.1"
                     /translation="MKKKWFFADYYDTTIILLALISAILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIILVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLLGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(1686..2672)
                     /locus_tag="VYO88_001922"
     CDS             complement(1686..2672)
                     /locus_tag="VYO88_001922"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1719961.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2866..5334
                     /gene="gyrA"
                     /locus_tag="VYO88_001923"
     CDS             2866..5334
                     /gene="gyrA"
                     /locus_tag="VYO88_001923"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1719962.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLVITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5334..>6056
                     /gene="srtA"
                     /locus_tag="VYO88_001924"
     CDS             5334..>6056
                     /gene="srtA"
                     /locus_tag="VYO88_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1719963.1"
                     /translation="MSQKKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIV
                     WNTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIP
                     ELEMNLPIFKGLDNVNLFYGAGTMKREQVMGKGNYSLASHHIFGVDNANKMLFSPLDN
                     AKNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERII
                     VKGDLKETKDYSQTSNEILTAFN"
BASE COUNT         1920 a          997 c         1315 g         1824 t
ORIGIN      
        1 atatagaaag aacgctgaga aggtgttctt tttatattga ctgaacacct aaaaagtaat
       61 acaatggtgt taccattaaa aaagggagca caaaagatga ctactattac attaaaagtt
      121 tctgaagctg ataaaacatt tatgaaagca atggctaagt ttgaaggagt ttccctttcg
      181 gaacttattc gcaccaaaac tcttgaagcc ctagaagatg aatacgatgc tcgtgtggca
      241 gatttagcct atcaagagta tttagaagac ttggaaaaag gagttgaacc cattacttgg
      301 gaagaaatga tgcatgattt aggcttgaag gatgaataat ttgtataaat tagttccaac
      361 aagacgtttc atcaagcaat tgaaaaaatt ggaccgttat acgcagaagc taattacaaa
      421 ctatttacaa atcaatgttt tggaagaccc aagacgacac ggaaaggctt tggttggtaa
      481 tcgcgttggt caatggcgct atagaattgg taattatcga gttatcgtac aaattgtaga
      541 tgatgaatta gttgttgcta ctctagaagt tggtcatcgg agagatattt attgaattaa
      601 agctgagtaa taacaatata gaaagtaagg agagtaaaaa tttgaagaaa aaatggtttt
      661 ttgcagatta ttatgataca acaattattt tacttgcttt aatctctgct attctggtat
      721 tacttggatt tgctgagatg attgatttgg acaatccgcc ttatagtatt attgatttag
      781 taatctgggg tgtttttgta attgattata gttggcgctt ttttattact aaaagaaaat
      841 ggcgctttat tcttgaaaat atttttgatt tattggctat tctcccttta aatgctattt
      901 tcacagtttt tcgattaggg cgtatctttc gtttagttaa actaacaaaa ttactgaaac
      961 tgactcgttt acttagaata attggactta caggtaaatt agaaagaaaa attagtagat
     1021 tcttacggac aaatggcctg atttatatct tatatgttaa tatctttatt attctagtag
     1081 gaagttcaat tttatctgta gttgaagaaa aatccttctc agatagtctt tggtgggctc
     1141 ttgtgacagt aactactgtt ggttatggtg atattgttcc agtttccctt ttggggaaat
     1201 ggctagcagt tttactgatg cttgtcggta ttggaacaat agggatgcta acaagtgctt
     1261 tgacgaactt ttttgtaaag gataatccag atgaacagat aaaacttgat aaactcaaag
     1321 acgaattatc gagctaaaga atattaatag agaaacaatc tgaaaaaatc gaagaactac
     1381 attgaatgat aaaagactta gttgaaaaaa tatcataaag gtgagacaaa ataaaacttg
     1441 attcgaggag aaatcaagta agtcttgaca caatagaacg catattatca ggtataaaaa
     1501 cttgatacta tgcgttttat agagaaataa aataaaatct gaacaaatca attaggaatt
     1561 taaagcattt tataacaacg ttttagagta atggggtgct atttcaactt caacctacta
     1621 taatacagaa aaaaatacag aaaaaaacaa ctccctgatg attcaaggag ttgtctatag
     1681 ttaaattagt ttttagaagc ttcttggaat tctggatttt tccatgcttc gtcaataata
     1741 gcttgcaatt ctttagcaga tgcttgcatt ttttgagttt ctgcatcgtt caatggaatg
     1801 tttactggac gaacgatacc atgtgcacca acaacagctg gttgaccgat aaagacattc
     1861 tcaactccgt attgaccttc ttggaatact gaaagtggaa gtactgcgtt ttcatcgtca
     1921 aggattgctt tagtgatacg agcaagggct actgcgatac cgtagtatgt tgcacctttt
     1981 ttgttgatga ttgtgtaggc tgcatcacga acaccttcga acaattcaat caattcagct
     2041 tcttgaacat tttgagtgtc tttaaggaat tcttcaaggt ttacaccagc gatgttagcg
     2101 tgtgaccaaa cagcgaactc agagtcaccg tgttcaccca tgatgtaggc gtgcactgaa
     2161 cgagcatcca catccaattt ttcagcaagt gcttgacgga aacgagctga gtcaagtgaa
     2221 gtacctgaac cgataacgcg ttctttaggg aaaccagaga atttccaagt tgagtaagtc
     2281 aaaacgtcaa ctgggttagc agcaacaagg aagatacctt tgaaaccaga ttcaacaact
     2341 tgagttacga ttgatttgtt gatagcaagg tttttaccta caaggtcaag acgagtttca
     2401 cctggttttt gaggtgcacc tgcagtgatc acaacaaggt cagcgtctgc acagtcagag
     2461 tattgagctg catagatttt tttaggtgaa gtgaaggcaa gggcgtgact aaggtcaagc
     2521 gcatcaccaa cagctttttc atgcaattgt ggaatttcga taattccaag ctcttgtgca
     2581 attccttggt taacaagtgc aaaagcgtaa gatgaaccta cagcaccatc accgacaagg
     2641 ataacttttt tgtgttgttt agttgaagtc attgttttaa acatctcctt aattttatta
     2701 ggggattttc cctagacaac ttcattctat cacttttaaa aaactttgtc acgaatatgc
     2761 cttatagttc tcgatgtaaa cgttttagtg gtttagaggc tgaaatagat gggaatttat
     2821 ggtataatgt tgttacttac taattgtgaa atgaggcatt tattaatgca ggataaaaat
     2881 ttagtgaatg tcaatctgac aaaggagatg aaggcaagtt ttatcgacta cgccatgagt
     2941 gttatcgtag cgcgagctct tcctgatgtt cgagatggct taaaacctgt tcaccgtcgc
     3001 attctctacg gaatgaatga attgggtgtg accccagaca aaccccataa aaaatctgct
     3061 cgtattacag gggatgtcat gggtaaatat cacccacacg gggattcctc tatttatgaa
     3121 gccatggtcc gtatggctca atggtggagc taccgttaca tgcttgtaga tggtcatggg
     3181 aattttggtt ccatggatgg agatagtgct gccgctcaac gttataccga ggcacgtatg
     3241 agcaagattg ctctggaaat gcttcgtgat atcaacaaaa atacagttga tttcgttgat
     3301 aactatgatg ccaatgaacg ggaacccttg gtcttgccag cgcgttttcc aaaccttttg
     3361 gttaatggag caactggtat cgcggttggg atggcaacca atattccacc tcataatctg
     3421 ggtgaaacca ttgatgcagt gaagttggtc atggataatc ctgaagtgac taccaaggac
     3481 ttgatggaag tcttgcctgg accagatttt ccaactggtg ctcttgtcat ggggaaatca
     3541 ggtatccata aggcttatga aacaggtaaa ggttcgattg tcctacgttc tcgtacagag
     3601 attgaaacga ctaagactgg tcgtgagcgc atcgttgtaa cagaatttcc ttacatggtc
     3661 aataaaacca aggtgcatga gcatattgtt cgcttggttc aggaaaaacg cattgagggt
     3721 atcacagcag tacgtgatga gtcaaaccgt gaaggtgttc gatttgttat tgaagtcaag
     3781 cgcgacgcct cagccaatgt tattctcaat aacctcttca aaatgaccca aatgcaaacc
     3841 aattttggtt tcaatatgct cgctatccaa aatggtatac cgaaaatttt gtctcttcgt
     3901 cagattttgg atgcttatat cgagcaccaa aaagaagtgg ttgttcgtcg tacacgtttt
     3961 gataaggaaa aagcggaagc gcgcgctcat atcttagaag gtctcttgat tgcgctagac
     4021 catatcgacg aagtgattcg tatcatccgt gctagtgaaa cggatgcgga agctcaagct
     4081 gagttgatga gcaagtttaa gctttctgaa cgtcaaagtc aagctatcct tgatatgcgt
     4141 cttcgtcgtt tgacaggttt ggaacgcgat aagattcaat ctgagtatga tgacctcttg
     4201 gctctgattg cggatttagc agatattctt gctaagcctg aacgtgtttc tcaaattatc
     4261 aaagacgaat tggatgaagt taaacgtaaa ttttctgata aacgccgtac agagttgatg
     4321 gttggacagg tcttgagtct cgaggatgag gacttgattg aagaatcgga tgtcttgatt
     4381 accctttcta acagaggcta cattaagcgt ttggatcagg acgagttcac tgctcaaaaa
     4441 cgtgggggtc gtggtgtcca aggaacggga gtgaaagatg atgactttgt tcgtgagtta
     4501 gtgtcaacta gcacccatga tcatctgctc ttcttcacaa acaagggacg tgtctatcgt
     4561 cttaaaggtt atgaaattcc tgagtatggt cggactgcca aagggctacc agtagtcaat
     4621 ctcttgaaat tggatgaaga cgaaagtatt cagacggtta tcaatgttga gtctgatcgc
     4681 agtgatgatg cttatctctt ctttacaacc cgtcacggta ttgtgaagag aaccagtgtt
     4741 aaggagtttg ccaatattcg tcaaaatggt ctcaaagcgc tgaatttaaa ggatgaagat
     4801 gagttaatca atgtcttgtt ggcagaagga gatatggata ttatcattgg taccaagttt
     4861 ggttatgcag ttcgctttaa tcaatcagcc gttcgtggta tgagccgtat cgccactggt
     4921 gtgaaaggtg ttaaccttcg tgaaggagac acagttgttg gtgccagctt gattactgat
     4981 caagatgagg ttcttgttat cacagaaaaa ggatatggta agcgtacagt cgctactgaa
     5041 tacccaacaa aaggtcgtgg tggtaaggga atgcagacag ctaaaattac cgaaaaaaat
     5101 ggcttgctgg ccggtcttat gactgttcaa ggggatgagg atttgatgat tatcactgat
     5161 acaggtgtca tgattcgaac caatcttgcc aatatttcac aaacaggacg tgcaactatg
     5221 ggagttaaag taatgcgcct ggatcaagat gctcagatag tgactttcac aacggttgcg
     5281 gtggcagaaa aagaagaagt tgggacagaa aacgaaacag aaggtgaagc ataatgtctc
     5341 aaaaaaaaaa taataaaaag aaaaacaagc gaaaaaattt gctgacaaat atcctagcag
     5401 gatttctgat attactgtca ctggctttga tttttaatac tcaaattcga aatattttca
     5461 tagtctggaa taccaataag tatcaagtta gccaggtatc aaaagaaaaa ttagaagaaa
     5521 atcaggatac agaaggcaat tttgactttg attctgtcaa agctatctct tcggaagctg
     5581 ttctaacttc tcaatgggat gctcaaaaat taccagttat tgggggaatt gcaattcctg
     5641 aattggaaat gaatttgccg atttttaaag gacttgataa tgttaatctc ttctacggag
     5701 ctggtacaat gaaacgcgag caagtaatgg gaaaaggaaa ttatagtcta gctagtcacc
     5761 atatctttgg tgttgataat gctaataaaa tgttattttc tcctttagat aatgctaaaa
     5821 atggcatgaa gatttatcta accgataaaa ataaagttta tacttatgaa atacgtgaag
     5881 tcaaacgtgt gacaccggat cgtgttgatg aagttgatga tagagatggg gtcaatgaaa
     5941 tcacattagt aacctgtgaa gaccttgctg ctacagaacg tattattgtc aaaggtgatt
     6001 tgaaagaaac aaaagattat tcacaaacat ctaatgaaat cctaacagct ttcaat
//
LOCUS       DAVLZS010000079         6052 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLZS010000079 DAVLZS010000000
VERSION     DAVLZS010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.079"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(286..837)
                     /locus_tag="VYO88_001925"
     CDS             complement(286..837)
                     /locus_tag="VYO88_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1719964.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(1187..2011)
                     /gene="nadE"
                     /locus_tag="VYO88_001926"
     CDS             complement(1187..2011)
                     /gene="nadE"
                     /locus_tag="VYO88_001926"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1719965.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(2008..3468)
                     /locus_tag="VYO88_001927"
     CDS             complement(2008..3468)
                     /locus_tag="VYO88_001927"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1719966.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(3584..4072)
                     /locus_tag="VYO88_001928"
     CDS             complement(3584..4072)
                     /locus_tag="VYO88_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719967.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGATYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(4062..4271)
                     /locus_tag="VYO88_001929"
     CDS             complement(4062..4271)
                     /locus_tag="VYO88_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1719968.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(4656..5135)
                     /locus_tag="VYO88_001930"
     CDS             complement(4656..5135)
                     /locus_tag="VYO88_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719969.1"
                     /translation="MKLNKQKNRMIYVLSNFLYAISVSIIYALNGIVLLVIVSKLGIP
                     GDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYKLKSGLVFGILVALLLFIPNILNTIM
                     MNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQYLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(5151..5870)
                     /locus_tag="VYO88_001931"
                     /pseudo
     CDS             complement(5151..5870)
                     /locus_tag="VYO88_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844502.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
BASE COUNT         1848 a         1297 c         1023 g         1884 t
ORIGIN      
        1 ttccctaact cgatagagga ttctatttta aatttaacaa cagctaggat tacactataa
       61 aaagtacatt accacctgtt cggctggaga atctagtcga ttagctccct cttagttaca
      121 agcttaaagc gattttttaa ctaatactaa accagattaa agaaggaact agaacatctg
      181 tcttgtacta atcaatatgc tattttaaag tttcaaataa acttggaatg ctaattatta
      241 tatttacaat aaatagttga cttcgataga aacagaaaat agaattcaac attcttccct
      301 acttatacca taataaataa gatccgcaag atagcctttt ctctctacac cattaacaat
      361 ggtttgtaga taggacattc cagccttttc catgacacga cctgaagctg ggttgagact
      421 ggcataacgt gctctgacct tttgaaaacc tgcttgagta aaacaaaagt ccaagatagc
      481 tttcaaggcc tctgtcatca taccatgtcc ccagtaagcc ttgcctagca catagccgat
      541 ttcacagctt aaatcagcct cgtctatctt aacaatgctg atatctccta tcacttgctc
      601 tgggttttct tttagacaaa tggcccattt ataatagttg agattagtat aggaagcaac
      661 ccaattgcga atcgagtttc gagtgatttc gatatcagga tggggatccc aggtaacata
      721 ggtcagattc tcagcggatg aagcccaatt ttgaaacata gcttctgcat cactctccac
      781 aaatcttctt aaaatcaaac gttctgtctg taatatttgc gtaccaatag atttcatgat
      841 gctacctcac ttccttattt ctatgctcgt agtaaaaagg ctcaactcag taacagctag
      901 aaaacgagtt tgtcttctaa tttcttgacg caatcgctgc ctggtttgaa atgcgatcta
      961 gcaagctttt tcaaacctag tcatcgttgc aggggtaaga cgatgaaatc gaactcttcg
     1021 agttaccgaa tctgcctcat tttcttattt ctaaactcgg ggttcaagat cccccagacc
     1081 ttctctcact ttcttatttt aagatgagag gctgaaaacc tccagtggag gtttttcttg
     1141 ctttttaatt tcagggcaag aagctaaaaa ggtcccccgg acctttttac tcccaaaagt
     1201 catcaaatac agtgatgggt aagtggcgtt tgtgttggcc tttgtgccac cagttttcaa
     1261 tggtcgcttg agcttctggg ctgattgttt tgccttctag gtagtcgtca atctctgcgt
     1321 aggtgactcc aagtgcgact tcgtcagcta ggcctggttt atcttcttct aggtctgccg
     1381 ttgggatttt ttcataaagg gctggctctg cgccaagttt ctgcaagagt tgttttcctt
     1441 ggcgtttatt gaggcggtaa agagggagaa tatccgcacc gccgtcacca aacttggtaa
     1501 agaaacctgt gatattttcc gcggcgtggt ctgttccaat gaccgctccg ctatgggaac
     1561 cagcaagggc atactgagca atcatacggc aacgtgcctt gatattcccc ttgttgaagt
     1621 ctgaaacagg actacctgtc gcttcaactg cagctgtcat ggcatcagct gattccttga
     1681 tattcacaac caagctgaca tctggctgga tgaaggctag ggctttttga gcatctgctt
     1741 catcagcttg cactccgtat ggcaggcgga cagcgataaa tttgtagcta tcgtctcccg
     1801 tttcagctcg cagttcttcc atagctaatt gcgccaaacg tcctgccaag gttgaatctt
     1861 gtcccccaga aatccctagt acaaaggttt ttaggaaggg atgttttttc agatatcttt
     1921 ttaagaaatc aatagaacga cggatttctt cctgggcatc aatcactggt ttgacaccca
     1981 gctcttggat aatcgtttct tgcaaactca ttcttcttct ccttcaccaa gggcttcctt
     2041 gcgcatctta tcaatcaagt ccatcttatc ttgccataca tcacgcgcca aatccactgg
     2101 atagtgctgc ggattgagca cacgcttata ctcatcccac aacttgtcaa attccttacg
     2161 ggcataatcc tgaatgtcag tcaaactagg caagttgtaa actaatatac cttctttgaa
     2221 gatatccacc aagagaggaa cggcatcaaa attacgaacc gtcttcttga tgtatgtata
     2281 ggtcggatgg aacatcttga tttctgtcat gtcgctaata tccacaccat cataagtgat
     2341 gtagtcacct tctgacttgc ctttttcacg actggtaatg cgccacacct gcttcttacc
     2401 tggcgtcgac actttttccg cattattaga cagcttaatc gtattgcgca tctgaccagt
     2461 ttcatcttcg attgcaacaa tcttgtaaac cgccccaaga gctggctggt cataggctgt
     2521 aatcagcttg gtacccacgc cccagacatc aatcttggcc ttttgcatct tgaggttgag
     2581 gatagtattt tcgtccaaat cattagaagc ataaatctta gcctctgtaa atccagcctc
     2641 gtccagttgc tgacggactt tcttagaaat gtaggcaata tccccagagt caatccgcac
     2701 acccataaag ttaatctgat cacccagctc acgcgccacc tgaatggcag ctggtacacc
     2761 gatgcgaagg gtgtcatagg tatccacaag aaagacacaa tttttgtggg tcgcagcgta
     2821 agccttgaaa gcttcatagt cattgccata aacctgtacc aaggcatggg catgggttcc
     2881 caaaacagga atgtcaaaga gcttacccgc acgcacgttg ctggttccat tggcgccacc
     2941 aatcacagct gcgcgtgttc cccagatggc cgcatccatt tcttgagccc gacgtgtccc
     3001 aaactccatc aagggttcat cttcgataac cgaacgaata cgagctgcct tcgtcgccac
     3061 caaggtctgg tagttgacga tgttcaaaag agccgtttcg accaactgac attgggctag
     3121 aggtccttcc acctgcacaa tcggttcatt agcaaaaacc aaatcccctt cttgggcaga
     3181 acgaacggtc aactccaact tgaaattgcg aaggtaatcc aagaacgccc catgataacc
     3241 aagcgactcc aaataggcta tatcactatc tgaaaaacgc aagtcttcaa gatagttcac
     3301 aattctttcc aaacctgcaa aaaccgcata gccgttctta aaaggctgtt ggcggaaata
     3361 cacctcaaag accgccttct tattgtgaat cccttggtca aagtaaacct gcatcatgtt
     3421 gatctggtac aagtccgtgt gcaatgtcaa actatcatct ggatacatac ttttcctact
     3481 tccttagcta gaaacccatg aaaattttca agaactttca tgtattccaa taaattagta
     3541 ctattatatc acattttagc tggattgaga aaagagtaac aagctattct ccactctcca
     3601 attcatccat atcttgttca aattttttct gagcccattc gccatagctc ttaagaccaa
     3661 gattgccaat aaagacccac ggaaggtaaa tgacataagt aatgacccaa gcagacaggt
     3721 atttaaaatt caaaggattg tgctgataaa tttctatgtt gaattgataa ttctgcaaca
     3781 tcaaaagagc cgtaatagcc aaggttagga aaaaacaacc caaaatcgta aaatgaaaac
     3841 gactatagta ggtcgctccc agataacggg cacgattgaa aaagtaaaat gtccctatga
     3901 tgataacgat tagcagcata ttagaattaa aaaggcttgg tgctaatact gaaatgatat
     3961 aagataggag cgacaaagca atgcagatat agaaactttc agagcccgct ttattgaaca
     4021 gttgttcttc tctttcgtct agtaattgat aataataaaa tctatttttc atcttcttcc
     4081 tcccaaaata gttggtctag ggttttccct aaacatctgc aaatagactg gcagagcgag
     4141 agactgggat tgtattttcc cgcctctatc aaaccaatag tctggcgtgt caccccgaca
     4201 gcctctgcca gttgaccttg tgttaaatca cgctctaccc gagctaattt taattttaaa
     4261 tttttagcca ccttcgtcct ccttatagtt ttaatactca tctactctta aaaaatccaa
     4321 aaccaacaca agctatcagc tatttattat aaccccatta atttgcactc cagtattatc
     4381 ttcagccgaa aatcagtatt ttaggttgtt tgaaataaac ttcctagttt actcttttat
     4441 ttttatttag tattagcttt agtaggatct tttaaacgag tttttattgc ttatatttct
     4501 tgtttagttt agttggtttc atatcactat tatataatgc ttttggaaat gagcctagta
     4561 taagtcaaaa acgtgttgaa tagtgaaagc aggagcatac caagatgact gattttttac
     4621 tgtattttag gtatgcaaaa taatactaaa taaaactaaa atgaatactt cttgcttttc
     4681 ttgagagtga aaaagtacaa taaaatgatt gtagtgatta gcacaagata ctgactaata
     4741 gacatcgtat ttgaagtcac aaatacaggt aaagaataaa aaggaagaag ttcaattgct
     4801 ttgataaaca aatcattact agtattcatc ataatcgtat ttaatatatt agggataaag
     4861 agtagtaaag ctactaaaat accaaatacc aagccacttt tcaatttgta taaatagaaa
     4921 atgtaagata atagaaaata aaacaggact aacaaaattg tattgactac aatagctact
     4981 ataaaatcta atcctaaatc acctggaata cccaatttac ttactatgac tagtaacaca
     5041 atgccattca aagcataaat aatggaaact gagatggcat atagaaaatt agacaagacg
     5101 taaatcatcc gattcttctg tttatttaat ttcatgatta taaccttcct ttattttgaa
     5161 cgatttaggt aaatatcttt aagcgtctct tttttagttt caaaatcaac tactttaata
     5221 gagttttcgt taaaaaattt aaaaagctca ctattttgaa tattcccaga catagtaatt
     5281 ctcaatccct cttcctaaac aatatcccaa aattcttgtt tggtaatgaa aatgtctcta
     5341 tctgtagctg atgaaaaagc tatctcaaac aagaaattat gactatcttt tcctactttt
     5401 tgaaatgtca aaagcccgtt ctccaagaaa agaaccctct cacaaatttc ttcaatatct
     5461 tctaatttat gactcgatat taaaattccc acattttcat gtaaagctaa attttttaga
     5521 accgataaaa ctatttgtga tgattcaata tctaaaccat tagtcggttc atctaaaatc
     5581 aatatatcag gttccgtaac gagagttaga agcaaagcta atttttgttt tgtacccaaa
     5641 gaataggtct ttactttttt attaatagac tgagtcaaat ctaactcttg gatcaaactt
     5701 ctaaatcttt cttgattgta gtcaacacca tataaatttg acaaatattt taaattctct
     5761 aaacctgttt tagataaaaa taattttggt tcttcgatta aatacccaac attatcactg
     5821 cttataatat tacctgaagt cggttgatta ttctgaacaa gaattttcat caacgtactc
     5881 ttaccaactc catttctccc tacttgacca acaatttcac ccttgttaag tgcaaaattt
     5941 atatctttga gaatgattga atgaccataa tgcttactta catttataac ttacattttt
     6001 tattcctcaa ttaatattca tggtttgctc tttgattctt attgagttta aa
//
LOCUS       DAVLZS010000080         6035 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLZS010000080 DAVLZS010000000
VERSION     DAVLZS010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.080"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..250)
                     /locus_tag="VYO88_001932"
     CDS             complement(<1..250)
                     /locus_tag="VYO88_001932"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719970.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDETNEVSSKHVFEVVDETNEVSSKHVFEVVD"
     gene            complement(314..1324)
                     /gene="ccpA"
                     /locus_tag="VYO88_001933"
     CDS             complement(314..1324)
                     /gene="ccpA"
                     /locus_tag="VYO88_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1719971.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(1749..2348)
                     /locus_tag="VYO88_001934"
     CDS             complement(1749..2348)
                     /locus_tag="VYO88_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1719972.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLMLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERNIADLMQTLHTVLEGRKEYSPELMEVVMMHPNPLTEQEIAVLKGIAQGFSNQEIA
                     DKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(2349..3446)
                     /locus_tag="VYO88_001935"
     CDS             complement(2349..3446)
                     /locus_tag="VYO88_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1719973.1"
                     /translation="MLERLKRIHYMFWISLIFMIFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILTFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKSSLTQEL
                     ESTASMILLELVTNIIKHAKASKVYLKLERTEKELILTVRDDGCGFASISGDELHTVR
                     NRVFPFSGEVSVISQKHPTEVQVRLLYKERK"
     gene            complement(3446..4183)
                     /locus_tag="VYO88_001936"
                     /pseudo
     CDS             complement(3446..4183)
                     /locus_tag="VYO88_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(4185..5069)
                     /locus_tag="VYO88_001937"
     CDS             complement(4185..5069)
                     /locus_tag="VYO88_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719974.1"
                     /translation="MNMIKVESLNKNIKGKAILKGISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELIAFFQRIY
                     PNSLSDQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTSLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLVQAGCGIQEIEV
                     NNRSLLDTIFEETQKGDN"
     gene            complement(5056..5250)
                     /locus_tag="VYO88_001938"
     CDS             complement(5056..5250)
                     /locus_tag="VYO88_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719975.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTGWFDQTLLRQFIRGALGFGFM
                     IFVVFLMRMEWLKGEYHEYD"
     gene            complement(5247..5378)
                     /locus_tag="VYO88_001939"
     CDS             complement(5247..5378)
                     /locus_tag="VYO88_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine aminotransferase"
                     /protein_id="HEV1719976.1"
                     /translation="MFSGLDESFYHFPWELFAGFGMMSWLVREGLKLVGDVKKELEE"
BASE COUNT         1912 a         1354 c          979 g         1790 t
ORIGIN      
        1 tatctacaac ctcaaaaaca tgttttgagc tgacttcgtt agtttcatct acaacctcaa
       61 aaacatgttt tgagctgact tcgttagttt catctacaac ctcaaaaaca tgttttgagc
      121 tgacttcgtc agttctatct gcaacctcaa agcagtgctt tgagctgact tcgtcagttc
      181 tatctacaac ctcaaaacag tgtgttgcgc agcctttaac cagccgccta gtccgctcta
      241 tggtattcat taagtcaaca tctcttgttt aagagcacaa aatcaggaaa tcttctcgat
      301 tccctgattt tttctattta cgttttcgtg ttgagctacg ttctgtcaaa ccatgaggta
      361 agagaacttc acgttcttcc aactcttcct tatgcataat cttggtcaac atacgcatac
      421 taatggcacc aaggtcataa agaggttggg caatcgttgt caagtttgga cgggtaaagc
      481 gtgagatttg tgaatcatca ctagtaataa tttcaaaatc ttctggcaca gaaacaccct
      541 tatcagccaa accgttcaag actcctgctg ccaactcatc acctgtcaca actgctgcag
      601 ttgcatttga tgaaatcaaa cgctctgcta aggcgtaacc atcatcatag ctatatttag
      661 attcaaatac caaaccctca ctataagtga ttcctgcttt tttcaaggtt tccttgtagc
      721 caactaaacg aaccttacca ttgatgtcat ccactagcgg accgctaacg aaagcaatac
      781 gctcattttc tttagcaagg taactcactg catcaattgt tgcttgctta tagtcaatat
      841 tgacacttgg caactggtgc tcaacatcga cagttcctgc gagaacaatc ggagtacgtg
      901 aacgcgaaaa ttctgagcga attttatctg tcaagtgata ccccatatag ataatgccat
      961 ctacctgctt tgaaaagagg gtattgacaa cagaaacttc tttctcgtta tcttcatcgc
     1021 tattagctag gacaatattg tacttgtaca tttctgcaat atcatcaatc cccttagcca
     1081 aactcgaaaa ataaccattg gtaatatttg gaatcacgac accgacagtg gttgtctttt
     1141 tacttgcaag accacgcgca actgcatttg gacgataatc caaacgatca attacctcta
     1201 gcactttttt acgggtattc tcttttacat ttttattgcc attgaccaca cggctgaccg
     1261 tcgccatgga aacacctgct tcacgagcga catcataaat ggttactgta tcatctgcat
     1321 tcattccttt tcctgtcctt tctatctcac acattctttt acaagtagag gtactgattg
     1381 aagctctata tctacttaca aaagtgaaga tgtgaaaatt tcgttttcat atttctactt
     1441 attccattct atcactaatt gtaaacactt tcaagtgttt tttgaagatt gattgaaaaa
     1501 atttcataga aaacctaggt ttagctcctt gctaccacct tagactaaac aaaaaggagg
     1561 aaactaagcc ctcctaaagt tatagtaaaa tgaaataaga acaggataaa tcgatcagga
     1621 cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct agtttcaatc
     1681 tactataggt attgttccat tcactaccgt caattttagc acatagtctt catgaaaata
     1741 ttatatcatc ataaccaacc agattctttc gcgatattag ctgcctctgt tcgattacct
     1801 gcatctagtt tcgaaagaat attggtgaca tagtttcgga ctgttccgtt ggatagataa
     1861 agtttgtctg caatttcttg gttagagaag ccctgagcaa ttccctttaa aactgcgatt
     1921 tcttgctccg ttaatggatt gggatgcatc atcaccactt ccatcaattc aggcgaatac
     1981 tccttgcgtc cttcgaggac ggtgtgcaag gtttgcatga ggtctgcaat gtttctttct
     2041 tttaatacat aagcatctac tccagccttg accgcacgtt caaaataccc aggacgcttg
     2101 aaggtcgtca ccacaaccac ctttgtttca agcttttctg ctcgtatcca ctccaagact
     2161 tcaagacctg tcttaacagg catttctacg tcaaggatgg cgatatctac agactccttt
     2221 tctaatagtt ggattgcttc ttgcccattc ttggcttgaa agacagactc tacatccggt
     2281 tgaagcatga gcaactggca catggcatct cgcaacatac tttgatcttc tgcgactaat
     2341 actttcatct actttctctc cttataaagt agtcgaacct gcacttcagt tggatgtttc
     2401 tgactgatta cacttacttc tcctgaaaat ggaaaaacac gatttcggac tgtatggagc
     2461 tcatccccgc ttatagaggc aaagccacag ccatcatctc tcactgttag aatgagttct
     2521 ttctctgtcc gttctaattt caagtagact ttagacgctt tagcatgttt gatgatattg
     2581 gtcactaatt caagcaaaat catggaagcc gttgactcca attcctgagt taagctagac
     2641 ttgtccaagt gattctcaac ttgaacctca attccagcaa tttctaacat ctttttcaca
     2701 gtctctagtt cggatgtcaa agttctagac ttaagatttt ccacaatggt tcgcacttca
     2761 ttcatggaat ccttgctgat ctggtgaatt tcttttaatt ccttttccac ctgtggataa
     2821 gcctccatct gaaataactg caaggctaaa tctgtcttga cactcagcat agcaaaggta
     2881 tgtcccagac tatcatgcaa atcctgaccg atacgactac gttcattttc agcaagcaat
     2941 agatttatct gggcattttg cttgacctga gcttctttca aatcctcgac aatacgaatc
     3001 cgaaccaatc caaaagtcat taaatcgaca aaagtaagaa ttacaagtag atagaataga
     3061 aactcaactt cgattctctg aaaaatcaac agttgcccca caacaaggac ttgagcaaga
     3121 agaaaagtcc agacatgtaa agactttaaa ctacgtacgc tgaaatgata acttaagaga
     3181 ttggatagga aaaagaaaaa ccagatataa ttaacagcaa caaaggcagt attcccaact
     3241 acataagtca gcatgaggcc ccaatatagc caagataggc gctggctctt agttgttaaa
     3301 acacccaaat atgccactac aaatagaata tcaatcaata aatgccaggc agaaagccac
     3361 ccagtcacta caggcaggat ggggaaaatc ataaaaatta aactgatcca aaacatataa
     3421 tgtattcttt tcagtctttc aagcattaag cattctcctt atgaccttga aggtaaatag
     3481 tcaaaccaaa taaaactgct gaaaaaacaa gtagataaac tgtggctgat agattgattc
     3541 caccctcatt taagaaggtc ttgattaatt ccatcaactg ataacttggt aaacgcttcc
     3601 cgattgcttg catccagtct ggaaataaag agacgggcat ccagagtccg cctaaaacag
     3661 ccaatcctag ataaagaaga ttgcccacga cagacatcag ctgactagtt ggtaacagcg
     3721 tcaaggttaa gccaagtgct acaaaagcaa tacttcccaa aatcagcaaa atcgcagctc
     3781 caacccattt tactagaggc atgtctacac ctcttacaaa atgtccaact gtaaaaacaa
     3841 ccagaattga gaccaaataa tcaaccagca tacttgttat ctttgataga taatattcta
     3901 ccatatttac tgggctatga cgtaatattt tctgccagtt gttcatcttg tcggtatgta
     3961 agacagctgg gaatgaaaag atagcggtcg acatcatgga aaagccagtc atggagatga
     4021 ggtaatcacg cataaaattc gcgggtccac ctggtgtgtc ctggtacatg ccagaaaaga
     4081 atagatagaa ggctgtcggc atccctactg acaatagata atagatcaat tgtcatttgg
     4141 tcaataaaaa ttctatctta ctaagtgcta gccatcgttt catcttagtt atctcccttc
     4201 tgcgtttctt caaagattgt atccaacaaa ctacgattat taacttcaat ttcttgtatg
     4261 ccacatcctg cttgaactaa cagttcccaa aaagcatctg cttcgcgtgt gactacttgt
     4321 agagcatcct gtttttgtga ccagttttca accaagttag actgctcaat gacttccttg
     4381 tatgccagag gaaggataaa atgcttttca attccctcac tacgcatagc tagagacgtc
     4441 gtatcacgaa tcaactctcc cttatttaaa accaaaatcc ggtcagccgt atgctctacc
     4501 tcttcaatat aatgagacga atagagaatc gtgactcctt gcgcttttag gtcccgaacg
     4561 atttcccaaa agcgttgacg agttgaagta tccatggcag cagttggttc atctaaaaag
     4621 acaagctttg gtcgcccaat caaggtcaag acaaaagaga agagacgctt ttgcccgcct
     4681 gacaattttt ctgcgaattg ctctttttgt tgctggtcaa actgcaatag ttgatcgatt
     4741 tcctgatcgc tcaaggaatt tggatagata cgttgaaaga aagcaatcaa ctctttgacc
     4801 tttaatttct gaacgatgac attttcttga ggcagataac ctctaatata gtctaactga
     4861 gaactcgtca ctgacaagcc ttggatggat acttgaccgc ttgtgaccag tttatctcca
     4921 agcagacagt ccaagagtgt ggtcttccca gcaccattgg gcccaatcaa ggcgacgcat
     4981 tcaccttcag ctacctcaaa ggaaataccc ttcaaaatag ccttgccctt gatgttttta
     5041 tttaggcttt ctaccttaat catattcatg atattctcct ttcaaccact ccattctcat
     5101 aaggaaaacg acgaaaatca taaatccaaa ccccaaagca ccacgaatga attggcgaag
     5161 caaggtttgg tcaaaccaac ctgtaaacat ttccactaac cataccaaga gtgacaggcc
     5221 gataaagaaa tagatgatcc ctctcttcat tcctcaagct cctttttcac atctccgact
     5281 aatttcaaac cttctctaac aagccaagac atcattccaa agccagcaaa gagctcccaa
     5341 ggaaaatgat agaaactctc atccaatccc gaaaacatga gttaggtcat aactcctgct
     5401 actactaaac tcactgcgat aatcatttta tttctcatct cttcttcctc catttcatac
     5461 tacaattata gtcttttgaa atcagaggag acagaagctt ctgtcactag aaaatatgac
     5521 aaatgtcata aaaaattctg ttcaaaacaa gcaagataca ctatacaata aaacacaatt
     5581 agaaaaatct aaggcaactt cctcaaaaga gatatcaaac ccaattcaca ccataatgta
     5641 aactaatact tatttaaaat caaaaagagt agaaattttt atcagacaaa cacatatata
     5701 gtgtattgaa tctataacag taggccttaa atactaaaat atttctataa attaatttaa
     5761 ctttcctgat agagctgttc atatcttatt tcaattctct aaattatacg ttgaacaaaa
     5821 cccttctatt tctttcttaa agatttataa gagttataaa atctgttaaa tttcaatgtg
     5881 tatacctaaa ctacggtatt tattgaaaag actggagaca aaaagtatac gctgccaaaa
     5941 tgaattactg aaaatcaaaa aagagagaac caaactgatt ccctcttaat gtatataata
     6001 tctagtttta aaaatacaca ctcacatatc tctgt
//
LOCUS       DAVLZS010000081         5630 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLZS010000081 DAVLZS010000000
VERSION     DAVLZS010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.081"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(293..1519)
                     /locus_tag="VYO88_001940"
     CDS             complement(293..1519)
                     /locus_tag="VYO88_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1719977.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1591..2256)
                     /locus_tag="VYO88_001941"
     CDS             complement(1591..2256)
                     /locus_tag="VYO88_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1719978.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSALVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2268..2945)
                     /locus_tag="VYO88_001942"
     CDS             complement(2268..2945)
                     /locus_tag="VYO88_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1719979.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMAALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            complement(3024..4280)
                     /locus_tag="VYO88_001943"
     CDS             complement(3024..4280)
                     /locus_tag="VYO88_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1719980.1"
                     /translation="MKKILNNKLYMKVLVSDLISNFGDTLYFIALMTYVTEIKSSNLA
                     ISIVNISETIPILFTIFFGIIADRTLNKVGMIIKTLWIRTILYLLVAVVMNFKESILV
                     VILASIVNLISDTLGQFENGLFYPISNRIVKKSDREETMAFRQTATSTMNIVNQSLGA
                     FLITFLSFFHLALINSLTFAISLLITLAIKSQINNFYIDKTPSTKVSKVDFKATFSDI
                     ISNLKLSLKHLFSLTNMKTVLLVIPILNGSLAIIIPLAVVNLSKSSALTIISSATTIS
                     VLGISTVSGGILGGTLILISKKFKNLSIENLLKMNLMTILLSFIAFYYQNIYFIVLTL
                     FLSSVFVSALNPKIGAIIFNNLDETKLATIFGGMVTYFQLGDVVSRLLFSTLVIYLSY
                     TYIAVIYMILVLIVAIYTFRRVQTTS"
     gene            complement(4309..5586)
                     /locus_tag="VYO88_001944"
     CDS             complement(4309..5586)
                     /locus_tag="VYO88_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase C family protein"
                     /protein_id="HEV1719981.1"
                     /translation="MRNIIKKYDEIINKVDSLVLDNNIIDLLQRSCYTENRSYLSEYP
                     SIIIYLSYRLANCDDNEHSKLLYNRVNYYLHELLKSIKLNSRNNISMCYGFSGYVYAL
                     KLLPKRSKEYSKLLETLETILVSLTRDRLSEIKKSNKVKEEYIDVIQGVSSVGKYFLS
                     KDKLTSNQELLLKGVLNYLAGVINNKPIIYPEYMPNEKLKRKFPNGYINLGVAHGILG
                     PLYVLALGFKKFNMPEYLISLKKGLSYYEKTFQTNKIGKIIGWNGRVSAEVESEKFEY
                     NLSWCYGSLGMARVLYNISKIIDIPKLQELATDVFHSSIYYLNSSEILNNAICHGRSG
                     IMLLFNLMYLDTGESQFKAISDNLFKEIVNKATDSEYIFVERDIYFRGVNYDEVIEYI
                     DFGLLNGVSGIVLALMAQRTGNASPLAEMFFMQ"
BASE COUNT         2083 a         1009 c          871 g         1667 t
ORIGIN      
        1 tatatacggc aaagtgaagc tgacgtggtt tgaagagagt ttcgaagagt ataagtaggc
       61 tgaaaagaat ccagctacag catggactat tatatagcag attgaaataa gatgagaaca
      121 aatcgattgg gaaagtaaaa ttaatttcta taaatgtttt agcaattgtt tcgtactatt
      181 ttagattcag tctattataa cacattcaga aaagagaaaa aagtctgttg attttgacca
      241 tcataaaaag actggcaatc cagtctcaaa catatattat agaaattctc cactaaatac
      301 tttcacgaat attcagaagc ataacaaagg caactagaag aaatagcaat aaaacaaagc
      361 taactgccag agttccaaag ctagtagcaa tggttaccaa agctattgta aataagctag
      421 gtaaaacaac cgtaatggca ccgatagagg attgaactgc tcccattgac tcctcaggta
      481 tttgtttaaa gacgagttct tgcaatctag gagagagaac acctgcgaaa aaggcatcca
      541 aggtactaaa gatgagaatc cagtcaaaac gaactgtggc aaatcctact agaagaagca
      601 actggatgac aagtgaggca tagagagctg tttttatgga aatggtatgt tgcagatagc
      661 cacttacaag gcttccgaca atcagggctg acagttcaaa agtggatagc aaggcaagag
      721 attgacctgt ttgtaaattc aaaaagggtt gattcctcaa aaatagagta gagacaggaa
      781 ctgtaacatt tatcactgct tgactagtag agataataaa caaaaccaag agcaccttat
      841 tcatattcca tatcaatttc gatgattgga gcaaatgctg gcaaaaggat tttacagaga
      901 gtccttcttg atagttaatc gttttttcta ctttcaagag gtcagttttt atgaagagga
      961 tacctaaaaa tgcgattaaa aaggtaagag cgttcagcaa ggaaatgaac tggatggaga
     1021 gaatccctag caagactcct cctagaatat tactgattgt tttcactaaa ctaacagttg
     1081 actgtttaaa tccaatagct tctgccagat ggtcttgccc aataattcta atgaaaatcg
     1141 gagtgagcat ggctcctgaa aagtaactca atgtgtcaga caagaggtta agcagacaaa
     1201 taaatgctac tagcaacaag gagaaagact gccctgaaag tgataaagaa acgatagagt
     1261 aaagcaaaaa ttttgcaaaa ctaatgactg tgtatttcaa gacacgatga tgttgaaaat
     1321 ctgccaaaac tcccagaaag atttgtaaaa tttggggaag ggtttctgaa atcgtaatga
     1381 gtaaaatcgc caaaggtgca aaagacgcat ctgccacata attcagaaag gccagataaa
     1441 aaatcgtatc cccaagcgtt gaaatccact ggttgatagt taattgccta aaatctctat
     1501 tttgaagaaa tactttcatc acaactcctt cttaagttca aatgggaatc tttccccaag
     1561 gatagaccgc gatactacta acaaccaaaa ttacagtaac atcaaaagct gaccaatgcc
     1621 attgtagact atatgcagtc caataggcca ataaattgac tttgtcattc taaataagac
     1681 tgcaaatata agacctccac ccatatagaa gacaaagtct gtcaagaccc aaccgtgatt
     1741 actaatgtgc gagaccccaa ataaaacagc ggaaccaagt acatctagcc cccatttctt
     1801 tcctttttcc agagcagtca tcactaatcc acgataaatc atgtcttcaa aaatgggacc
     1861 tgcaatcaca ggataaaaaa aatacatcaa aaatgccgta gctcctgtaa aagtaggagc
     1921 agcatgttga taagaaattt catttcgagt aggtgggaaa agaaaaaagg tgacaaaatt
     1981 ccaagcaaca aaagcaagca gagctaggaa ggaatagaaa agataggatc ctttaaactt
     2041 tctactattg attttctgcc atttccccga ccaaatcata gcaataagag caaataaaac
     2101 cacaagaaaa ttcaacatca tatccgacag ataataggca aagtcagata gcccagtaac
     2161 aaggtcactg cgtaaaacta gagcactgaa cttctggtca gcaataacta gtagaaaaac
     2221 tataataaag tagcggtgtg agattatctt tttcatatat cacctttcta atatccaaat
     2281 accaataaag taacaatgag taagaaacta ttccatgaag catgcagagc tatagcccaa
     2341 tagatggatc gggtgtagcg aaacatcata caaaatatca agcccattcc aaaatacttt
     2401 atgaaatctg tcgttatcca accatactgc aaaacatgca tagcgccaaa tatggcagcg
     2461 gaaacaagaa catcaagata gtatctctta actttagata aacttgtcat caaaagacca
     2521 cgacaaacaa cctcttctga tacaggtgcg ataatactag tataaagtat tcgcgtaaca
     2581 aaatagctaa ttcctgttaa attggtggct acttctacga ctgtacttcc attctgggta
     2641 cgaggaaaga tataggttgt tagatttgcc cacacgaaca ataagaaaaa agaaagaagg
     2701 aaaacaccca ggtaagacca acgaaactgg aaacgaccac actctttcca atgttcactt
     2761 ttgacaaaag caattgtagc tatagttccc agaataagta ccaataaaac ttggaacaca
     2821 tagtacatat tatcagacaa agcagccata aaatctaagt ctgatgtgac attaaaaatg
     2881 aggtaataag tcaaaatcaa caagccagtt gctaggtgaa atttcacttc tttcattttc
     2941 ttcatcctat tatctcctat aagagcctat tttatatcta attgcaagga ctggaggaat
     3001 aaagttaaaa tttcaaaatt ctctcagctt gtagtctgta ctcttctaaa agtatagata
     3061 gccactatta aaactaatat catatatatc actgctatat aagtataaga taaatagatt
     3121 accaatgtag aaaacaataa tcttgatacg acatctccca actggaagta agtaaccatt
     3181 cctccaaata ttgtagctag tttcgtttca tcaagattat taaatatgat agctcctatt
     3241 ttaggattta atgcactgac aaatacactc gaaagaaata atgttaatac tataaaataa
     3301 atattttggt aataaaacgc aataaatgat aataaaatag tcattaaatt cattttcaat
     3361 aagttctcta tggaaagatt tttaaatttt ttactaatta gaatcaaagt tccacctaaa
     3421 atccctccag aaacagtact aattcccaaa actgaaattg ttgttgcaga actaataatt
     3481 gtaagagcag aacttttaga aagattcact acagctagtg gtatgataat ggctaagctc
     3541 ccattaagaa ttggaataac aagtaataca gtcttcatat tagtgagact aaatagatgt
     3601 ttaagcgaaa gttttaagtt tgaaataata tcagaaaacg tagctttaaa atcaactttt
     3661 gaaaccttag tggatggggt cttgtctata taaaaattgt taatttggct tttgatagct
     3721 aatgttatta gtaaactaat agcgaatgtt agagaattta taagagctaa gtgaaagaaa
     3781 ctaagaaaag tgattaaaaa tgcccctaac gactgattta caatgttcat ggtagaagtt
     3841 gctgtttgcc taaacgccat ggtttcttcc ctatctgatt ttttcactat tcgattagaa
     3901 attggataga aaagaccatt ttcaaattgc cccaatgtat ctgaaataag attaactata
     3961 ctagcaagta ttactactaa aatggattcc ttaaaattca tgacaacagc cactaataaa
     4021 tataaaattg tccgtatcca taacgttttg ataatcattc ccactttatt aagtgtccta
     4081 tctgcaatga taccaaaaaa tattgtgaac aatataggta tagtctccga tatatttacg
     4141 attgagatag ccaaattgct actcttaatc tccgtcacat aagtcatgag agctataaaa
     4201 tatagtgtat ctccaaagtt tgatatcaga tctgaaacca agactttcat atatagctta
     4261 ttatttaaaa tttttttcat atgttatccc tatatctacc ttaaaccctc actgcataaa
     4321 aaacatttca gccaaaggag aagcatttcc tgtcctctgc gccattagtg caagaactat
     4381 cccagaaacc ccatttaaca agccaaaatc aatatactct atcacttcat cataattcac
     4441 acccctaaaa tatatatcac gttccacaaa tatgtattca gaatcagtgg ctttatttac
     4501 tatttcctta aataaattat cagaaatagc tttaaactgt gattcccctg tgtctaaata
     4561 catcaagttg aacaaaagca ttatcccaga gcgaccatga caaattgcgt tatttaaaat
     4621 ttcactacta ttaaggtaat aaatagatga gtggaataca tcagtagcta actcttgtaa
     4681 ttttgggatg tcaattattt tagatatatt atatagtact cttgccattc caagactacc
     4741 ataacaccaa cttaaattat attcgaattt ctcactttct acctcagcac ttactctacc
     4801 attccagcca ataatcttgc caatcttatt agtttgaaaa gttttttcat agtaactcaa
     4861 accctttttt agcgaaatta aatactctgg catgttgaat tttttaaacc ctaatgctaa
     4921 aacatatagt ggtcctaata taccatgagc tacacctagg ttgatatagc cattggggaa
     4981 ttttctcttt aatttttcat ttggcatata ttccggataa ataattggct tattatttat
     5041 tactcctgct aaataattta aaactccttt taataatagt tcctgattag aagtcaattt
     5101 atccttgcta agaaaatact ttcctacact agaaactcct tggattacat caatatattc
     5161 ttctttaact ttattggatt tttttatttc acttagccta tctctagtta aagatactaa
     5221 aattgtttca agtgtctcta gcaatttact atattcttta ctcctcttag gtaacaattt
     5281 caaggcatat acatagccag aaaatccata gcacattgat atattattac gactgttcaa
     5341 cttaatcgac tttaacagtt catgtaaata gtagtttact ctattgtaga gcaacttaga
     5401 atgctcgtta tcatcgcaat tagctaatct atatgataaa tatatgatta tgctggggta
     5461 ttccgacaag taacttctat tttccgtata gcacgagcgc tgtagtaaat caataatatt
     5521 attgtctaac actagactat ctactttatt gatgatttca tcatacttct taattatatt
     5581 tctcataatt atttaatacc tctaaaatat acctcacaaa ataaagatat
//
LOCUS       DAVLZS010000082         5475 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLZS010000082 DAVLZS010000000
VERSION     DAVLZS010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5475
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.082"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            63..1817
                     /locus_tag="VYO88_001945"
     CDS             63..1817
                     /locus_tag="VYO88_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719982.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAILTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGL
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            1801..3522
                     /locus_tag="VYO88_001946"
     CDS             1801..3522
                     /locus_tag="VYO88_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719983.1"
                     /translation="MKEFYKKRFALTDRGARNSSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3533..4117
                     /locus_tag="VYO88_001947"
     CDS             3533..4117
                     /locus_tag="VYO88_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1719984.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMTLVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            4117..4812
                     /locus_tag="VYO88_001948"
     CDS             4117..4812
                     /locus_tag="VYO88_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1719985.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKIRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            4800..>5475
                     /locus_tag="VYO88_001949"
     CDS             4800..>5475
                     /locus_tag="VYO88_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1719986.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSE"
BASE COUNT         1964 a          717 c         1025 g         1769 t
ORIGIN      
        1 tagatattat caattaagcg aatttatatc taaaagggat attaaagaaa ggagatatgc
       61 ttatgaagat ttacaaaaaa ctatttgctt atgtccaaga taagaaatat cttggggttt
      121 tggccataat tttttctgct atatctgcta tacttacagt atatggatat tatttaatct
      181 acaaatttct agataagtta ataattaatt caaatttatc cggtgcagag agcatagcat
      241 taaaatctgt tattacacta acaagtggag cgatatttta ttttgtctca ggaatgtttt
      301 cacacatctt gggatttagg cttgaaacaa atttaagaaa aaggggaatt gatggcttag
      361 agaaagcaag ttttaggttc tttgacttaa atccatctgg tcaaataaga aagattatag
      421 atgacaatgc tgcacaaact catcaggtgg tagcacacat gattcccgat agttctcagg
      481 caataatcac acccgtactt gtacttgcac ttggctttat agtaagtata agagttggct
      541 taattttgct tgctcttact ataattggtg gcttaatttt aggggcaatg atgggcgagc
      601 aagaatttat gaagatatac caagaatccc tatctaaact aagtgctgaa actgttgagt
      661 acgtgagagg aatgcaagtt gtaaaaatat ttaaagcaaa tgtagagtct tttaaaagct
      721 tttataaggc gataaaagat tactcaaagt atgcttatga ttattcccta tcttgtaaaa
      781 ggccttatgt tttgtatcaa tggttatttt ttggactgat tgcaatttta attattccta
      841 tagtttattt tatgactagc ttagctagcg caaaggtgat tttacttgag cttatcatga
      901 ttttattttt atcaggagtt ctctttgttt cattcatgag aatgatgtgg tactccatgt
      961 atatttctca aggaaattat gcagtagata ctttagaggc gctttacgaa gatatgcaaa
     1021 aagacaaatt agtgcatggt aatgtcaata attttaaaaa ctataatata gaatttgaga
     1081 atgttagctt tgcttataat gataaagctg tcattgaaaa tttatccttt aatttagaag
     1141 aaggaaagtc ctacgcactt gtcggttcat ctggatcagg caaatcaaca gtagcaaaac
     1201 ttatatcagg tttttacaat gttaatgaag gaagcataaa gataggcggg atagcaataa
     1261 gtgaatattc tgacgaagcc ttaattaaag ccatttcctt tgtttttcaa gattcaaaat
     1321 tattcaagaa gagcatttat gataatgtag ctttagctaa taaagatgcg acgaaagatg
     1381 acgttatgag agccttaaaa ttagcaggat gcgatttaat attagacaaa ttcccagaaa
     1441 gagaaaatac aatcataggc tcaaaaggtg tttatttatc cggtggagaa aaacaaagaa
     1501 ttgcaattgc tagagcaatt ttaaaggatt ccaaaattat tattatggat gaagcatcag
     1561 catctattga cccagataac gagtttgaat tgcaaaaagc ttttaaaaat cttatgaagg
     1621 ataaaacagt tatcatgatt gcacacaggc tatctacaat taaagacctt gatgaaatta
     1681 ttgtcatgga tagtggaaaa attatagaaa gagggtctga caaagaatta atgtcaaaag
     1741 atacaaggta taagagcctg caagagatgt ttaacagtgc gaatgaatgg agggtttcaa
     1801 atgaaagagt tttataaaaa aagatttgct cttacagata gaggagcaag aaattcaagt
     1861 aaagcaacac tggcttcatt tttcgtttat tgtataaaca tgcttcctgc catattactt
     1921 atgatttttg ctcaggaagt tttggaaaat atgggcaaaa gcaatggctt ttatatagta
     1981 ttctcagttt tgactttgat agcaatgtat attttgcttt ctatcgaata cgataaatta
     2041 tataacacaa cctatcaaga aagtgcagat ttaagaataa ggacagcgga gaatttatca
     2101 aaattacctc tatcttactt ttctaaacat gacatttccg acatttcaca aacaatcatg
     2161 gctgatattg aaggcataga gcatgcaatg agccactcaa taccaaaggt gggcggcatg
     2221 gtactgtttt tcccattaat atctgtaatg atgctagcgg gcaatgtcaa gatgggttta
     2281 gctgtaatta ttccatctat tttaagcttt atatttatac ctttatctaa aaaatatcag
     2341 gttaatggac agaatagata ttatgatgtc ttaagaaaaa actcagaaag ctttcaagaa
     2401 aatatcgaaa tgcaaatgga gattaaagca tataatttat cgaaggatat taaagatgac
     2461 ttatataaaa aaatggaaga tagtgagaga atacacttaa aggcggaagt aactacaatt
     2521 ttaactttgt ctatatcttc aatatttagc tttatatctc ttgctgttgt gatatttgtc
     2581 ggcgtaaatc taattattaa taaagagata aattctctct accttatagg atatttacta
     2641 gctgctatga agataaaaga ctctttagat gcatctaaag agggcttgat ggaaatattt
     2701 tatttatcgc ccaaaataga aagattaaaa gaaattcaaa atcaagattt acaagaaggc
     2761 gatgactata gcttaaaaaa atttgatatt gatctaaaag atgttgagtt tgcctacaat
     2821 aaagacgcaa aagttttaaa tggtgtaagt tttaaagcta agcagggaga ggtcactgct
     2881 ttggtaggtg caagtggctg cggtaaaaca actatcttga aacttatatc aagactttat
     2941 gattatgaca agggacaaat cttaatcgat ggcaaagata taaaagaaat atcaacagaa
     3001 tctctttttg ataaggtctc tatagttttc caagatgtgg ttctctttaa tcaaagcgtt
     3061 atggaaaata ttagaatcgg aaagcaagat gcaagtgacg aagaggttaa aagagcagca
     3121 aaacttgcaa attgcacaga ttttatagaa aaaatggata aaggtttcga tacagttatt
     3181 ggtgagaacg gagctgagct atcaggagga gaaagacaaa gattatcaat agccagagcc
     3241 ttcttaaaag atgcgccgat attgatctta gatgagataa cagcaagcct tgatgttaac
     3301 aacgagaaaa agattcaaga gtctttaaat aatttagtta aagataaaac tgttgtaatc
     3361 atttcacata gaatgaaatc catagaaaat gcagacaaga tagtagttct tcaaaacgga
     3421 agagtagaaa gcgaaggtaa gcatgaagag cttttacaaa aatcaaaaat ttacaaaaat
     3481 ttaatagaaa agacaaaaat ggcagaagaa tttatttatt aggaggacta caatggataa
     3541 taaaaaatta aaagtaaaag atttagtaag tatcggtgtt tttggcgtaa tttattttgc
     3601 cttcatgttt ggagttggta tgatgggctt gattccaata ttgttcttaa tatacccgac
     3661 agtattagcc atagttgcag gaactgttgt tatgttattt atggctaagg ttcaaaagcc
     3721 atgggcacta tttatatttg gtatgatatc accacttgtg atgtttgcag ctggtcatac
     3781 ctacgtagtt gtggttttat cacttatagt aatgataata gcagaattaa ttagaaagat
     3841 tggtaattat aattcattta aatacaatat gctttcttat gcaatcttca gcacatggat
     3901 atgtagctct ttaatgcaaa tgcttttagc aaaagaaaaa tatatggagt ggtctttgat
     3961 gacgatggga aaagattatg ttgatgtatt agaaaagtta ataacttatc ctcacatgac
     4021 tttagtagcc ttaggtgctt tcttaggagg aattcttgga gcatatatag gcaaggctct
     4081 attgaaaaaa cactttgaaa aagcaggcat cgtataatgc ctactttttc ttcaaatgct
     4141 ccctttaatc ccaatccgat ctctaagata ttagtcgtat ttatcacagg cttaactgtt
     4201 atgcatagca taaacatccg ttttgagctg gcaattgttt gtcttattgg tattttgctt
     4261 tatttgaatg gatacaaaaa aacacttttc aaatggatta tattgtgtgg gatactttac
     4321 tccttgccta attttatggt gttatctgaa ttaaacccta tagttaagat gtttttgagt
     4381 atacctattg ttattagaat gtttatttta ccatttatgg cagcaagctt tatgataaag
     4441 acctcggatg taggcgcaat aatttcatcg atggataagc ttaagatttc aaagaatgta
     4501 tccataccta ttgcggttat gtttagattc ttcccatctt ttaaggagga gaagaaaaac
     4561 atcaaaatgg ctatgagagt aagagggata aattttaaaa acccagtcaa atatcttgaa
     4621 tatgtttctg tgccactact cattatatca tctaatatat cagatgacat tgcaaaagcg
     4681 gcagaaacaa aggcaataga aaatccaatt gccaagatca gatacattcg cgtaaagata
     4741 cagctaattg attttgttta tgttttagcg gttgctggac ttattgtggg aggcttaata
     4801 tggttgaaat aaaaaattta agtcttgatt atggtgaaga gcatatatta gatgatatat
     4861 cactatccat agccgaggga gagtgcgtgc tatttacagg aaaaagtgga aatggtaagt
     4921 catctttaat aaattcaatc aatggactag ctgtaaggta tgacaacgca aagacaaagg
     4981 gcgaaataat tattgatggt aagaatataa aaaatttgga actttatcaa atctcaatgc
     5041 ttgtttcaac tgtttttcaa aatcctaaga catatttttt taatgtcaat acgacattag
     5101 aattattatt ttatttggaa aatatcggtc ttgcaagaga agagatggac aggcgtttga
     5161 aggatatgct tgagatattc ccgataaaaa atcttttaaa cagaaatata tttaatctat
     5221 ccggcggtga aaaacaaatt ctttgcattg cagcttctta tatagcaggt acaaagatta
     5281 tagttatgga tgagccttca tcgaatttag atattaaaag cataagtgtt ttggcaaaga
     5341 tgctaaagat attaaaagag aaaggcataa gcataattgt tgcagagcat agaatttatt
     5401 atttgatgga catagttgac cgtgtatttt taatagataa aggaaagctt aaaaaaactt
     5461 atactagaag tgaat
//
LOCUS       DAVLZS010000083         5388 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLZS010000083 DAVLZS010000000
VERSION     DAVLZS010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5388
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.083"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(127..294)
                     /locus_tag="VYO88_001950"
     CDS             complement(127..294)
                     /locus_tag="VYO88_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719987.1"
                     /translation="MSLIYSSAKKDFLYWNVLIFIMELPNDVKVQFYELRKKVQSFNQ
                     LSKRFGMDVSG"
     gene            complement(461..532)
                     /locus_tag="VYO88_001951"
     tRNA            complement(461..532)
                     /locus_tag="VYO88_001951"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(497..499),aa:Arg,seq:cct)
     gene            complement(575..922)
                     /gene="rplS"
                     /locus_tag="VYO88_001952"
     CDS             complement(575..922)
                     /gene="rplS"
                     /locus_tag="VYO88_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1719988.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1041..1370)
                     /gene="crcB"
                     /locus_tag="VYO88_001953"
     CDS             complement(1041..1370)
                     /gene="crcB"
                     /locus_tag="VYO88_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1719989.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1364..1738)
                     /gene="crcB"
                     /locus_tag="VYO88_001954"
     CDS             complement(1364..1738)
                     /gene="crcB"
                     /locus_tag="VYO88_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1719990.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(1735..2001)
                     /locus_tag="VYO88_001955"
     CDS             complement(1735..2001)
                     /locus_tag="VYO88_001955"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1719991.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKCSRDYQDQNIK"
     gene            complement(2117..2560)
                     /locus_tag="VYO88_001956"
     CDS             complement(2117..2560)
                     /locus_tag="VYO88_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1719992.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            2664..3599
                     /locus_tag="VYO88_001957"
     CDS             2664..3599
                     /locus_tag="VYO88_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1719993.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3653..3937
                     /locus_tag="VYO88_001958"
     CDS             3653..3937
                     /locus_tag="VYO88_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1719994.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3994..4212)
                     /locus_tag="VYO88_001959"
     CDS             complement(3994..4212)
                     /locus_tag="VYO88_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719995.1"
                     /translation="MSISPRFETLEQAIAFKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(4209..5103)
                     /locus_tag="VYO88_001960"
                     /pseudo
     CDS             complement(4209..5103)
                     /locus_tag="VYO88_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         1678 a         1151 c          938 g         1621 t
ORIGIN      
        1 aatacatttg ttattatata ggcttttgtt gatttatttc ttgttttaat tcagtggaat
       61 agtaacgatt cttccctttt ttaacgctct ctgttcaata acgatcaatt caccttgtca
      121 cataccttag ccagaaacat ccataccaaa tctttttgaa agctgattaa agctttgtac
      181 tttctttcta agttcataga actgaacctt aacgtcattt ggcaattcca taataaaaat
      241 aaggacattc caataaagga agtccttttt agcactacta taaatcaaag acatttttat
      301 gatccatttt attctataat cattgaccaa aatataattt ttggtcaaaa tttggtcaaa
      361 aaaattaaaa atgctaaatt atttttaaaa atgaacttga gaaaattgcc ttcaaataaa
      421 cattttgaat tttctttgtc tttctttaca ttactaaaaa tgccccctgc aggaatcgaa
      481 cctgcaacta ctccttagga gggagttgtt atatccattg aactaaggga gctagataaa
      541 aactctgctg aaaaagcaga gttttttagt cgaattaacg acggatttct ttgatacgag
      601 ctgccttacc ttgaagagca cgcaagtagt acaatttcgc acgacgtact ttaccgtaac
      661 gaacaacttc gattttttca acacgtggag tgtggattgg gaagatacgc tcaacaccta
      721 caccgttaga gattttacga actgtgtagt tttctgagat tccagcacct ttacgtgcga
      781 taacaacacc ttcaaaaatc tggatacgtt cacggttacc ttcgacaact ttcgcatgta
      841 cacgaacagt gtcaccagga cggaatgatg ggatatctgt acgaagttga ccttcagtca
      901 agctttggat taatggattc attttattct cctatctttg tcaatcttga ggaaacttcc
      961 tcagcggata aactgtattt ttgtgcgtcc atcacacaca agatacagtc taccaaattt
     1021 tcacaaaaaa gtaaagaaat ttatagcaaa attcctaaaa aaatcgcaac caaaccacct
     1081 atgtaagtca aagtcaggta agaataaaag accttcttat cacttagcag tctttgaagt
     1141 tcgtcattca aggtcgaaaa agttgttaaa ccgccacaaa atcctgttgc tagaatagca
     1201 tatacttcct tagactctac atgattgtag aatactccaa ttaaaaaaca acctaaaaga
     1261 ttagctatga gcgttccgag tggcaattta gaagcttgat tgtagcggga aaagaaatac
     1321 cgtacgagtg ctcccaagcc acaggcgatt gcaagataga cgattaccat ttcttcctcc
     1381 ctagaaaata agctaagagt aggcctccac cgatgctcaa aagcaaatac agtatcaaac
     1441 taagataacg ccctgtatca agcagcttca cagtatcaag cattaggctg gaaaaagttg
     1501 ttaaacctcc gcaaaaaccc gtccccagtg ctaaaatcaa gcccttacta gtccccttat
     1561 agaccagata gcccttgaca agataaatca agcagaaaat tcccagatag ttgacaaaga
     1621 gagtgcccca agggaaatct ggactggctg gtaaccaagt ggaaactagg tagcggacaa
     1681 gtccgcccaa catagcagct agaaaaatcc ctagcggata aaattgttct tttttcattt
     1741 gatattttga tcctgataat cacgcgaaca tttgagtatg tccgaaaaag tcgcgacaat
     1801 agtctcctga tagcgcttgt cctctacacg acttctaacc ttttcaaaaa taactgcttc
     1861 tctcttagta tctaaaatcg gtttccctga agccttctta taagcgacaa ctccttcaac
     1921 taagtgcatt cgttcttcta acagtttgac aatttggtcg tcgatttgat cgatttcttg
     1981 acgaataata tctaaatcca tacagtctcc tcctttattt gaattattgt atcaaaaagc
     2041 catcaattag gctagtaaaa tcccaactct cgataagaaa aatgcactga ttgattacat
     2101 cagcgcactt ttatgcttat cctactttag caaccaattc ttctgcgaat tgttccaagc
     2161 gttcaatatc ttcttcctcg gcagaaagat caactttaac acactctgaa cctttttctg
     2221 ctcctgttga cacaaagaca cggtcaaagt catcaacagc cttacagaat tcatcgtaga
     2281 aggtatctcc tgagccgacc actccgtaga ttttgccatt caagttgaga tctgctaggt
     2341 cttcgtagaa gtccatcatc tcatctggca attcaccatc accataagta taggtcgcaa
     2401 cgatagcgat gtctgcttcc aagaagtctg aagcgtcaac agttgtacat tcatcaacat
     2461 caacatccaa gcccaagtca cgtaatttgt ctgctacaat atctgcaatt tcttcggtat
     2521 taccggtcat actggcaaat acaatttttg ctaatgccat atcgtcctcc tcaatttatc
     2581 tttctccatt atatcacatc tttttcattt taaaaataaa aattcttgtg ctacaatgaa
     2641 atgagaaaga attgaggtta tttatggaga tttgccaaca aattttagaa aaaattaaag
     2701 aatacgacac cattatcatt catcgtcata tgaaaccaga ccctgatgcc ttgggaagtc
     2761 aggtgggatt gaaagccttg ctagaacatc atttcccaga aaaaaccatc aaagccgtcg
     2821 gttttgatga accaactctt acttggatgg ctgagatgga tcttgttgaa gatagagcct
     2881 accaaggcgc acttgtcatc gtctgtgata cagctaatac tgctcgtatc gatgataagc
     2941 gctatagtca aggtgatttt ctcattaaga ttgaccacca tccaaatgat gatgtatacg
     3001 gtgacctgtc ttgggtcgat actagttcaa gtagcgctag cgagatgatt accctatttg
     3061 cccaaacaac ccaactagcc ttggcagatc gcgatgctga gttgctcttt gcaggaattg
     3121 tcggtgatac aggtcgcttc ctctaccctt ctaccactgc acggactctt cgcctggctg
     3181 cttatttgag agaacataac tttgactttg cagctctcac tcgcaaaatg gacactatga
     3241 gctacaaaat tgctaaactg caaggctaca tctacgacca tctggaagtg gatgaaaatg
     3301 gtgctgctcg cgttatcctg agtcaagaag tcttgaaaca atacaatgta accgatgctg
     3361 aaactgcagc cattgtcggt gcacctggac gcattgacag agtgagtctc tggggaattt
     3421 ttgtcgaaca ggctgatggc cactaccgag ttcgcttacg cagtaaaatc catcctatca
     3481 atgaaatcgc caaggagcat gatggtggag gccaccctct agcaagtggt gctaattcct
     3541 atagcctaga agaaaatgaa atcatctacc aaaagttaaa aaacttgctt aaaaactgat
     3601 aaaatacttg ccaaactttt cagaatctga tagactagta tggtaacaat ctatggctcg
     3661 caaagagacc atggcagaaa ggaaatattg caaaatgaaa aaagatatcc atccagaata
     3721 tcgcccagtt gtcttcatgg acacaactac tggttaccaa ttccttagcg gttcaacaaa
     3781 acgctctaac gaaacagttg agttcgaagg cgaaacttac ccattgatcc gtgtggaaat
     3841 ttcatcagac tcacacccat tctacactgg acgtcaaaag ttcactcaag cagatggacg
     3901 cgtggatcgt ttcaacaaaa aatacggtct caaataatga taaaagaaca gtttcgactg
     3961 ttcttttttg tttcttgaaa tcaactgctg ttttcatgtt ccagactcat ctgtaggttc
     4021 ggtttccatg ctactaggca ggaaggaaat agctgtttca acacgtccat aatgagctgt
     4081 actattgtca cgaaccacac tttcattgat ggtccaagtg gaattcattt tcttaaaagc
     4141 ttctcggact ttttccaaat ctttgaaggc aatggcctgc tctaaggttt caaaacgagg
     4201 acttatactc atctgctttc acaaagcatt ctagtccatc tccgattaac gatggacttt
     4261 atcacctcct tctccagtcc ttgtatgaca tcttgaagtt gattcatgat atcttccaaa
     4321 gttcgaaagg ctttattctt aaatccacgt ttacgaatct ctttccacac ttgttcaatg
     4381 gggttcatct ctggtgtgta tggaggaata aaggtaaaac caatattagt cggaatcttt
     4441 aaggtacttg atttatgcca tatagcattg tccataacga ataaaagata atcatctgga
     4501 taagcttgtg aaagctcttc taaaaaggcg ttcatccact cagtattaca tctaccagct
     4561 attaagaaaa atgattcgcc tgtatgggca tcaacagctc cataacaata gcgaaattct
     4621 cgtatatagt gactatggac atgtggacct actcctattg gagaccaaca agatcccagt
     4681 ttactgattc taccgaaacc agcctcatct tggtacatca agcgaacctt atgaaaacgt
     4741 ctactatatt taaaacgctt tcttgtcttc ttgaattgag attttatttt tagacgcgac
     4801 aatggtttga gcgtctgctt tcttaggatg ttctggacgt ggcataatat ttcgccaacc
     4861 atggcgcttc aacagttgat agaaggcatc acgtgtgtag gaacgatata agcctgaaat
     4921 aaggtattgt aacaaattct cctgcctctg tagccttcaa atggcgggca agaaaggctt
     4981 tctcttcctc aactgtcata tatgcatggt tacgaccacc acgtgtttct tgaaggagag
     5041 agtcgagtcc gaactcctca tattttttac atttcgccaa atcgttgttt gattacagtc
     5101 tatagtgtat tgaatctata atagtacacc ttggctacta aaatatttct ataaattaat
     5161 ttgactttcc tgatagagtt gttcacatct tatttcaaat cactataaaa gctctataat
     5221 ctctttataa gatttgccca tcagacgaaa tataataaat tgaaactaga atagtacacc
     5281 tctacttcta aaacattgtt agaaatcgat ttgactgtcc taatcgattt gtcctgttct
     5341 tgtttcattt tactatagaa cgatttgaag gcgtttatga tatttagc
//
LOCUS       DAVLZS010000084         5377 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLZS010000084 DAVLZS010000000
VERSION     DAVLZS010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.084"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            168..452
                     /locus_tag="VYO88_001961"
     CDS             168..452
                     /locus_tag="VYO88_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719996.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            445..693
                     /locus_tag="VYO88_001962"
     CDS             445..693
                     /locus_tag="VYO88_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719997.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            789..1007
                     /locus_tag="VYO88_001963"
     CDS             789..1007
                     /locus_tag="VYO88_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1719998.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(1375..3699)
                     /gene="pflB"
                     /locus_tag="VYO88_001964"
     CDS             complement(1375..3699)
                     /gene="pflB"
                     /locus_tag="VYO88_001964"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1719999.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            4048..5109
                     /gene="dinB"
                     /locus_tag="VYO88_001965"
     CDS             4048..5109
                     /gene="dinB"
                     /locus_tag="VYO88_001965"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1720000.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
BASE COUNT         1687 a          989 c         1062 g         1639 t
ORIGIN      
        1 catttctaaa cattcttttc taagatgaaa aacagaattt ttcgattgtg atttaaagca
       61 acaagaagat tttcagtatc atcctataga tacgagctaa ttaagaaaaa ctacattttc
      121 gaatataaac tacaataata taaactaaat tttataggag gaagacaatg gattggtacg
      181 attatatgat acaggcatcc aaacaatcac aattcaacgc aagccattgg tttcgctatt
      241 tgcgaaaagt tatttttgaa gactattctt atttaacaaa ccaagatgta gaaaagttgc
      301 tagactccaa agaactaacc cgttttcaaa aaattagctt gaagtatgcc tttcaagagc
      361 atactccaac tcataaatat gtgatttcat taaataaacc tgctaagtta accaatgttc
      421 aaaaattgat ggagaaatac aaacatggat aaaatgaaac cggtcttcca agccctaaat
      481 aaggaattaa ttcaggaaaa tctgacttta acaattatct gtgtcgatgg ttatgtctta
      541 gaatatcatg gtttacgtgc cacacaagat gttgatgctt tttatgacca aaatcagaaa
      601 atcaatgaaa ttattgctcg tgtaggaaaa cagtttaatc ttaacatcca cgaagagtta
      661 tggctcaaca atcatgttgc aaagcaaata tgaacaaaca acctccctta agtttatgcg
      721 aatccttgta ctcatttgag aatctgaccg ttttagtagt ccctattgag tatgtgttag
      781 gaatgaagat gatgagtatc agagagcagg atttgcaaga tattggtgca attattaaat
      841 acaaaaactt tcattcacca ttcgatacct ttaaatattt aaaagacatg ggatttgata
      901 ctattgacct ctctgttcta ttagaaggtt ttagttatgc ttatggtatg gattggttag
      961 aaaaattttt taaagaaaat caagataaac ttcgcgaatt ttattaacag tatcaaacaa
     1021 gatgattgtc aattagccag tcgtcttgtt ttttatgatg aaatgaaata aaatctgaac
     1081 aaatcgctta gagaattcca gtcaatttct agcgctgttt gagacgtttc agtggactat
     1141 agtaaaatga aataagaata ggacaaatcg atcaggacag tcaaatcgat ttctaagaat
     1201 gttttagaaa taaaggtgta ctattctagt ttcaatctat tatatttcag attcggtcca
     1261 ctattccttc ccaaaaacat tgcatattgc gccgaaggaa ttgctcatac tatcccaagc
     1321 acaaaaccct cagtcgtttg accgagggtt ccttttcatt attcaaaaac ttgattagct
     1381 caatgcatcc aaggcatcat ccattgaaag aacttcgtgg aagacacgtt gtgtcaattc
     1441 agttttttgt tctggagtga ggtatttagt atttacacag tatccagaga tacgtacgat
     1501 aacgtcttca ccggacatga ttttttcgta aacatcgttc aagtccataa cgttcaagtt
     1561 aacgtgttgt ccaccgtttt cgaagtaacc atcaaggatt gttaccaagt tatcaacttg
     1621 ttcatcacga gtcttaccaa gagcgcgagg tgatacttgt gtagtcaatg agataccgtc
     1681 agctgcataa ctaaagtcaa ggctagaaag tgagttcaag ttttgcaacc aaccaccttt
     1741 agctttgtta gatgggttag cacctggtga gaagaattca agtttagaca agttcacaga
     1801 accatcttcg ttgaggtata cacctttgtg aactggtgag ttaccagttt gtttagagta
     1861 agcaacgtta gatgtgattg tcaaaagtga tactgtagct tctgcgtctt tgtatagttt
     1921 gtggctacgt agacgagttg tgtaagcttc gatcaaccat tctgccaatt cgtttgaacg
     1981 tgggtcatct tcaccccagc gtgggtagtc accgattgtt tcgtaatcgt agatgtagcc
     2041 atcttcgtca cggattggtt taactgtagc gtatttgata gctgacaatg tatcaacagt
     2101 gttagcaaat ccacagatac cgaatcccat gttggcacgt tgtttagttg gcaagaaggc
     2161 catttgaaca gcttcgtagt tgtacctatc agtcatgtag tggatgatgt tcaaggcatc
     2221 tacgtaagtg tcagtcaacc agtcaagaga tttttcaaag ttcgctttaa ctgattcgaa
     2281 ttcaagaact tcgtcacgga ttggttcgat atcaaatact ttgtagtctt tgtgaacatc
     2341 gtcgtaacca ccattcaaac cagtaagaag ggctttaaga acgtttacac gagcaccgaa
     2401 gtactggatg ttgtggcgtt gttcttcatt ttctggatca agtggagaca cacagcatga
     2461 gatacagctc atttcaccat atccgtcttt agccattgtt gttacacctt cgtattggat
     2521 agaagagtgt ttgtggctca tgtgcataca gtagcgacgg aagttgtatg gcaatttgtc
     2581 agtccaaaga actgtcaagt ttggttctgg tgagttaccg atgttgtcaa gagtgttcaa
     2641 gaaacggtag tccatcttag taacacggtg acgaccgtcg ttacccatac cagccataga
     2701 agttgtgata aaggttgggt cacctgagta caattggtca taagcttttg tacgagcaaa
     2761 tttaactgta cgaagtttca taacgaaatc atcaacgaat tcttggattt ctgattcagt
     2821 aaatgtacca cgagcaaggt cacgttctgc aaagatgtcc aatacgattg gtacacgacc
     2881 tagagatgta gcagcaccgt taatcacacg gcagacagcc atgaaagcaa tgttaaccca
     2941 ttggattgct tctttcacgt tcatcgctgg tttgcgaaca tcaaccccgt aaaggtcacc
     3001 caggcgaaca acttgttgca atgcttggta ttgaaggttt acttcttcac gaagacggat
     3061 tgtttcttca tcgatttctt tgattgcatt ccagtcgttt actttttctt gcatcaagta
     3121 gtctgcaccg taaagagcaa gacgtgcgta aacaccgatg atacgtccgc gtgagtatgc
     3181 atctggaaga ccagttacag tgtgtgcatg acgagcgcga cgaatatttg aagtgtaggc
     3241 acggaaaata ccgtcgttaa ctgttgttac atatttagtg aagatttcgt gaacagctgg
     3301 gtctggttcg tatccatttt cttttaaagt agtttcagcc atacggatac caccttttgg
     3361 catgaagttc aatttgaaga gttcatcatt ttggatacca aagataactt cattttcttt
     3421 gtcgataaat ccagcaggga tatcagcgat agatgttgga cgagtgtcca ttgggaaacg
     3481 agtttcttcg tagtgtgctt tagtttcttc tacaattttc ttgatgtgaa gtgaacgctc
     3541 tgttggtcct gcaaggaagc tttcgtctcc atcataaggt gtgtagttag cttgtacaaa
     3601 tcgtgataca cttgcttttt ctttccaatc tacgcctttg aagccttccc aagctttgtc
     3661 aaaaatatct tgtgcttcaa caactgtctt aacaaccata ttaatgtcct cttttttcta
     3721 gtaacagtca tctgttacat tcataagaca agtataccat atagtaaccg atttcaacaa
     3781 gtgaaaattc cctattttta cactttcttt tctaaaacag tctatatttt atttcaaact
     3841 gtattatatt tttgaaaaaa ataaagtcct tttttctttt tttcagaaaa aagggtataa
     3901 taaaagaaaa taagcagtaa cactcaatgg aaatcgaaaa gcaaactagg aagctagccg
     3961 cagattgctc aaaacactgt tttgaggttg cagatagagc tgacgtggtt tgaagagatt
     4021 ttcgaagagt ataaaaaggt gctaggcatg ttgatttttc ctttgttaaa tgatttgtca
     4081 agaaaaatca tccatattga catggatgcc ttttttgctg cagtggaaat cagggataat
     4141 cctaaactca gaggaaaacc tgtcattatt ggaagcgacc ctcggcaaac aggtggacgg
     4201 ggagtcgttt ctacctgtag ttatgaggca agagcttttg gtgtccattc tgccatgagt
     4261 tccaaggaag cttatgaacg ttgtccccag gctgtcttta tctcagggaa ttatgagaaa
     4321 tacaagtctg tgggactcca gattcgagct atttttaagc gctatacaga tttgattgaa
     4381 cccatgagca ttgacgaagc ctatttggat gtgacagaaa ataaactcgg tatcaagtca
     4441 gcggtcaaaa ttgctcgcct cattcaaaaa gatatctggc aagaactcca tctaactgct
     4501 tccgcaggcg tttcttacaa caaattctta gctaaaatgg cgagtgatta tcaaaaacca
     4561 catggtttga cagtgattct acctgaacag gctgaggatt ttctcaaaca aatggatatt
     4621 tccaaatttc atggagtagg aaaaaagaca gtagaacgtc ttcatcaaat gggcgttttt
     4681 actggtgctg atttacttga agttcctgag gtaaccctaa tagaccgttt tggtagacta
     4741 ggctatgatc tgtatcgaaa ggctcgtggc attcacaact ctccagtcaa atccaatcgc
     4801 atccgtaaat caatcggcaa ggagaaaacc tacgggaaga ttctccttgc tgaggaagat
     4861 atcaaaaaag agctgactct tctatcagaa aaagtcgctc tcaatctaca tcaacaagaa
     4921 aaagctggaa aaattgtcat tttgaaaatc cgctacgagg acttttcaac tcttaccaaa
     4981 cgaaaaagtc ttgctcaaaa aacacaagat gctagtcaga taagccaaat agccctgcaa
     5041 ctctatgaag aattaagcga gaaagaaaga ggtgtccgcc tattggggat taccctgact
     5101 ggattttaaa gctcaatgaa aatcaaagag caaactagga agctagccgc aggctgctca
     5161 aaacactgtt ttgaggttgc agataaagct gacgcggttt gaagagattt tctaagagta
     5221 taaaaccttg aagagttgcc ccttcaaggt tttttcttag gctctataat atttgtagtg
     5281 ggtaaatcca ctatagatat tatggagcct attttattgt agaaaaaaag tcccatatga
     5341 cctataatga aaagcgacaa aaccatcatt agaaaga
//
LOCUS       DAVLZS010000085         5215 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLZS010000085 DAVLZS010000000
VERSION     DAVLZS010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.085"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(358..1086)
                     /locus_tag="VYO88_001966"
     CDS             complement(358..1086)
                     /locus_tag="VYO88_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1720001.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1244..2653
                     /locus_tag="VYO88_001967"
     CDS             1244..2653
                     /locus_tag="VYO88_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1720002.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2671..3966
                     /locus_tag="VYO88_001968"
     CDS             2671..3966
                     /locus_tag="VYO88_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1720003.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGKNIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3971..4279
                     /locus_tag="VYO88_001969"
     CDS             3971..4279
                     /locus_tag="VYO88_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1720004.1"
                     /translation="MKQILLVCNAGMSTSILVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4276..4584
                     /locus_tag="VYO88_001970"
     CDS             4276..4584
                     /locus_tag="VYO88_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1720005.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1757 a          882 c          945 g         1631 t
ORIGIN      
        1 ggagattgaa attcatttct agcaattttt tagaagtcac agtctactat tctaacctca
       61 gtatactata tgtgttacaa gaaaagactc aaaaacttct cgtcagtgta agaatgtttg
      121 aaacactatt taaaactaaa taactataag aagtagatca agtgaacaat ttcagtacct
      181 actctataag ctatacgaag atatttttca acatgatgga taaaacgatc actcttttaa
      241 agccatctta tttagaaaag agaaaccatt taagcataga tggaaccttc ttgccctgtt
      301 ttaaattttt cttaaactag agtctgtaaa agattggctt cattttcaca ttttctccta
      361 ggaggaatgt cgtaatgcaa aagaattaaa ttcaaataaa tcatagcgat gacgactaat
      421 cgagtactca aacggagttc cgttatccaa ataagccact tgttctactt caaataccgg
      481 ttccgttgga aggagctgca agtaatgttg ctcattttct gaactagaag aagctcgtaa
      541 gatttttgta gcactggcaa tatgcaatcc taactttcct tcaatgtaat tgtaaatcga
      601 tttttgtaaa atatcttcag taatacctgg aataacatcg gtactcatat aagtttgttc
      661 cagaacataa ggtttaccgt caataatacg caggcggtaa atattataaa ctggactctg
      721 caaagcgacc tgtagttttt ctgctaaaaa ttcatttgca aattctaatt tgaagtgaat
      781 aatcctcgag tcaattgtag aatgagcatc ttcagatatt tttgtcagtc cccggatatc
      841 tctttctgga acgattaatt ttctttttga gctgccacga gagagaacaa aggttccctg
      901 cccacgtttt ctaaaaatta agccctcaga aactaacaag tctaaagctt ttttgatcgt
      961 cattcgacta caggcaaact gtttagctaa tgtcatttca tcaggcaatt gttcgttcat
     1021 ggtatattta ttacaaagaa tcttttcacg aatctcattg taaataaata aatattttgt
     1081 actcatttaa tctggttctc tctataatat tctaatagta gtataacaaa gttcaagaaa
     1141 tgaggcaaac acaagatatg tatcaacaat ttttaaaatt gtctagacaa attttaaaat
     1201 tatgctatac tttatgtata gaataataga aaggaggttg agcatgaaaa aaaagttagt
     1261 atttcctaat ctgttttggt ggggagctgc ttctagcgga cctcagacag aaggtcaata
     1321 tggaaaagta catgaaaatg tgatggacta ctggttcaaa acgcatccag aagatttttt
     1381 cgataatgtc ggacctcttg tagccagtaa cttttttcat acttacaccg aagatttcca
     1441 cttgatgaag gaaattggag ttaattcttt ccgcacttcc atccaatgga gtcgactcat
     1501 caagaattta gagacaggtg agcctgatcc aaaaggtatt gctttctaca atgccatcat
     1561 tgaagaagct aaaaagaacc agatggatct tgtgatgaat ttacatcatt ttgatttacc
     1621 agtggaactt cttcaaaaat acggtggttg ggaaagcaaa catgtagtgg agttattcgt
     1681 gaagtttgcc aagactgctt tcacatgctt tggagataag gttcattact ggacaacttt
     1741 caatgagcca atggtcattc cagaagcagg atacttatat gctttccatt atccaaatct
     1801 aaaaggaaag ggaaaagagg ccgtacaagt catctataat ctaaaccttg ctagtgcaaa
     1861 agtgattcaa ctatatcgct cattaggact tgatggaaag attgggatta ttttaaactt
     1921 gacacctgct tatccaagaa gtaattctcc agaagactta gaagcaagtc gatttacaga
     1981 tgacttcttt aacaaagtct tcttgaatcc agctgttaaa ggaactttcc cagaaagatt
     2041 ggtaaaacag ctagagagag atggcgtgtt atggagtcat accgaaaaag agcttcaact
     2101 gatgaaatca aatacggttg attttcttgg agtaaactac taccatccaa aacgtgttca
     2161 agcacaagca aatcctgagg aatatcagac gccctggatg ccagaccaat acttcaaaga
     2221 gtatgaatgg ctggagcgtc gcatgaatcc atatcgtggt tgggaaattt ttccgaaagc
     2281 catttatgat attgctatga ttgtgaagga agaatatggt aatatcccat ggtttatcag
     2341 tgaaaacgga atgggtgttg aaaacgaagc acggtttatc gatgaaaatg gagttatcga
     2401 tgacgtgtat cgtattgaat tttatgaaga acatttaaga tggctacata aagccattga
     2461 agagggaagt cactgttttg gataccacgc ttggaccgca tttgattgct ggtcttggaa
     2521 taatgcatat aagaatcgtt acggatttat ctccgttgat ttagaaacgc aaaagagaac
     2581 catcaagagc tcaggaagat ggtatcgcaa agtaagtgac aataacggtt ttgaagtaga
     2641 aattgaggag taaagagagg agatattcat atgaaaaact caaaatttat agaccaattt
     2701 gccacctttg ctggtaaact agggaaccaa attcatttaa aaaccctaag agatgcattc
     2761 gtaacagtaa tgccattata tattttggca ggtttaatcg ttcttttgaa caacacggta
     2821 tttaagtgga ttttccaagg ggatacatta acaagattcc aatattgggg aataacaatt
     2881 gcaaacggta ctttaagtat ttcaggtatg attattgctg taatggttgg ttatttctta
     2941 gctaaaaaca gagatttcga aaacccgtta gcagcatcaa tgctatcatt agtttcttta
     3001 attgtgatga tgccaaatac agtttctgta gttcctgacg gagcaaaaga tgcggtaaac
     3061 atttcaggtg ttctttcatt caacaacaca ggtacaggcg caatgttcgc cggggttatc
     3121 gtagcgatta ttgcaacaga attattcatt gaattatcaa acgttaaagc tttacaaatg
     3181 aaccttggta aaaatattcc accagctgtt agtagatcat ttagcgtatt acttccagtc
     3241 atgaccgtca tctccttatt tggggttgtt tcagcattat tattcaatat aactggaatg
     3301 aacttaatct caatcattac aatctttatt caagaaccaa ttcgtcatat tggtacaagc
     3361 ttaatcgggg tcattattat ttactcttta ggaaatatgt tatggctatt tggtattcac
     3421 caagcagtta tttacagtgc catcctagaa ccattactat taattaacat tactgaaaac
     3481 atcactgcag caaataatgg acaagccatt ccacacatca tcaacctatc acaaatacaa
     3541 acattcgctt taatgggtgg tagtggatct acattatgtt tattaatagc aacattctta
     3601 gtgagtcgca atgctgtctc taaaaacgtg gctaaattat cttttggacc tggtatcttc
     3661 aatatcaatg aaccagtatt attcggttac ccaatcgttt ataacatttc attagctatt
     3721 ccatttatca cagttccagt ccttggtatt ttaatcagct acttagcaac agttacagga
     3781 ttcatgagtc ctgcatttat acaagttcct tggactacac cagtattctt aaatgcatgg
     3841 ttagcaacag caggggacgt gagagcagtt ctagttcaat tcatcatctt tgcacttgga
     3901 gttcttctat acattccatt tatcaaagtt aatgacaaag ttgttgaaca agaaatggaa
     3961 ggttaagatt atgaaacaaa ttttattagt atgtaatgcg ggaatgtcga caagtatact
     4021 tgttaaaaaa atgcaacaaa gtgcgactga acgtgggatt gaaatctcta tccaagcaaa
     4081 atcaatgaca gaagctaaaa agaatatcca tgaagcagat gtcattctaa ttgggccaca
     4141 aattcgttat gagttacttg ctgtgaaaga aattgcagga aatatccctg tagataccat
     4201 tgatatgcgg gattacggaa tgatgaatgg agcaaaagtt ctggaacaag cacttgcatg
     4261 gataggagaa ataagatgac agaagaaatg gaatatatct gttttcagct cattgccaat
     4321 agtggagcag ccaaatcatc ctttattgaa gccatccaac tagctaaggc aggaaattta
     4381 aaagaagcga aaattaaagt tgaagaagcg gaagactcct tagtagaagc gcacaagatt
     4441 cactctaatc tcatacaaaa agaagctact ggagaaaaaa taggattctc cttgctattt
     4501 atgcatgcag aagaccaaat ggcttcaaca gagattattc agttactatc taaagaattc
     4561 atcgatctct atcaaaataa ataggaacac tgtcattccc atctgtcttt attaatgacg
     4621 actacattgt aggaacctcc aaaagttgga caaaatgatt gaaaggattg gatcctgcat
     4681 tacacaagat ccaatccttt tcttttactc tagtttttat aatatgttga atctagaata
     4741 gtccactgca gtttctaaaa aatttctgga aatggatgtt aagctccaat ttatttgttt
     4801 atatcttatt tcagtttact atactagctt attattctag tgaaaaattg aatgagccac
     4861 tatttattta atatgtatga tgagggaatg actcaaaaac ttcttgtcga tataagaaca
     4921 tctgagatag tattttaaaa cgaaaggact ataaaagctc atttccttcg cacttatttt
     4981 atagagatct atcattatac tctttagaaa tcaaaaagca acacaccttg tcatcgtttt
     5041 atcgtaaatc tgttaatgag ggggctagtc ttatctgcaa tctcaaatca gtgttttgag
     5101 ctgaatggca ctcgttttct cgtttgctct ttgattttaa ttgggcctta gtaaatacta
     5161 ctcttaaatt aaactatagt gaattgaaat aagatgtgaa caactctatc aggaa
//
LOCUS       DAVLZS010000086         4426 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLZS010000086 DAVLZS010000000
VERSION     DAVLZS010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.086"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            1..488
                     /locus_tag="VYO88_001971"
                     /pseudo
     CDS             1..488
                     /locus_tag="VYO88_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            416..868
                     /locus_tag="VYO88_001972"
     CDS             416..868
                     /locus_tag="VYO88_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720006.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNTTIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1700..2059
                     /locus_tag="VYO88_001973"
     CDS             1700..2059
                     /locus_tag="VYO88_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720007.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            2069..2398
                     /locus_tag="VYO88_001974"
     CDS             2069..2398
                     /locus_tag="VYO88_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV1720008.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQV"
     gene            2421..4276
                     /locus_tag="VYO88_001975"
                     /pseudo
     CDS             2421..4276
                     /locus_tag="VYO88_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261786.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
BASE COUNT         1657 a          630 c          860 g         1279 t
ORIGIN      
        1 agcagaggca atcataaaaa atggaataga aatagttgta gtaactgatc ataatactac
       61 caaaggtatt aaaaagttac aaatggcagt ctcaatcata atgaaaaatt atccgattta
      121 tgatatacat cctcatattt tacatggagt agaaattagt gcagcagata aattgcatat
      181 tgtatgtata tatgattatg aacaagaatc atgggttaat caatggttaa gtgaaaatat
      241 tataagtgag aaagatggaa gttatcaaca ttcactgact ataatgaagg atttcaataa
      301 tcaaaaaata gttaactata ttgctaattt caatagttat gacattttga aaaaaggttc
      361 tcacttatta ggtgcatata aacgaaaaat tttttctaaa gaaaatacac gatttttgga
      421 gtttaatatt aactcgaaag aatcttcgca acaacttgat attctctata aagaagttgg
      481 tgtattaagt ttgggacaaa aagttgtagc catgcttgat tttttattag catatagtga
      541 ttattctaaa gacttcagac cattgattat tgatcagcct gaagacaatc tagacaatcg
      601 ttatatttac aggcatttag ttcagcagtt tagagatgtg aaagctcaac gtcaaattat
      661 tttagcaaca cataatacta caattgtaac aaattctatg acagatcaag ttgttattat
      721 ggagtcagat ggagttaacg gatggattga atcacaggga tatgttagtg aaaaatatat
      781 aaaaaatcat atcatcaatc aattagaggg aggaaaagat tccttcaagc ataaaatgtc
      841 tatatatgag acggctttat cagagtagag tcagaaaaag taggttagaa atttagccta
      901 cttttttctt tgtccgacag gcatagtgta catctgaggt ccaagtcctc tgtggatatt
      961 tgctgcagat gaaaccaata gcgactccta agcctgaata tcgtgaggta ggggggatag
     1021 gaaggaatta gcgaaatcaa ggttctacaa acagaatcgt gacttgaagc catatatagc
     1081 ggatgaggaa ctctaaaatc caaataggtg tcgtaaccta tatacgtaaa ttacgagagt
     1141 aaactaggaa agatgtacgg cttattccgt gagcgtttag gacgtagtac aacgaatcat
     1201 gggagtcagc tgaacacata gtattgaaga aatttctgta atggaaatgg agcgaagaag
     1261 tgaacaatta aatgaatacc tctctaatta aatttgtcaa ttctaattcc tggtatgaaa
     1321 agacagtgac ctgaaaatgt aaacgatggg agctgatcat aaatatagga cggtacatgc
     1381 agtggtgtta gagattagtc cttacttgat ttgtgataac ttccccaaat ttcttctgct
     1441 atacttttct caacttttaa aaatccaact aagaatttta cctgggggtt tgggggcgga
     1501 gccactaagt tatcttatcg ttagctgtca aaactggtag gttttgatag gctggcgata
     1561 tgatttttgg gatattgtgg acacaatatc tgagctcgca aagaccgaac aaggagagac
     1621 tgaggtcttt aggaatcgta ctgacaatgt gaggcagcct tacattgtca gacaagtata
     1681 atgttgaaag aatggtaaga tgggacaaga aattaagtta atccgtaagc aatttagaat
     1741 cacgagacaa gaagaaaaac agataaaaga aatgatgagg gaacaaaaag tggatagttt
     1801 ctcagaattt cttcgtcaaa atttattgaa aaagaattat caggatagaa tttttgaaag
     1861 ttggttctcc ctttggcagt ctcaaaagtt tgaacagatt agtcgagatg tgtatgaagt
     1921 tctggttgtc gcaagagaaa atcatcaagt gactcaagag cacgtctcaa tcttattgac
     1981 ttgcgttcaa gaattgattg cagaagtgaa tcaagtacag ccactcagtc gtgagtttcg
     2041 tgaaaaatat atgggttagg aggatgtaat ggtttatcgc tatcgtacca atctcaaaaa
     2101 agtatttcta actgatccag aattacacca attgaatgaa cggattgcta agagcaattg
     2161 tcaaaatttt tcagtctatg ccagaaaagt tttgcttaat cccaatatgt catttgtcac
     2221 gattaacact gatacttatg accagttagt ttttgaattg agacgtattg gaaataacat
     2281 caatcaaatt gcgcgtgcga ttaatcaaag ccatctgatt tctcaggacc aattacaaga
     2341 attgagtaaa ggagtcggag agttaattaa ggaagtggac aaagaatttc aagtgtaggt
     2401 gaaaagactg aaggagtttc atggtagtta ctaaacactt tgcgacgcac ggaaaaaaat
     2461 atcgtaggcg tttgattaaa tatatcctca atccagataa aacagataat ctaaaattag
     2521 tatctgattt tggcatgagt aattacttag attttcctag ccatacagaa atggtagaaa
     2581 tgtacaatgt taactttact aataacgaca agttgtacga gtccagaaat gaccgacaag
     2641 aaaaacacca acaaactatt catgcccatc atctcatcca atcattttct cctgaagata
     2701 atctgacacc tgaagaaatt aaccgcattg gttatgagac catgatggaa ttgacaggag
     2761 gtcgttttaa gtttatcgta gcaactcaca cagacaaaga tcatgttcat aatcacatcc
     2821 taatcaacgc tattgaccgc aattcagata aaaagttgat atggaactat gccttggaac
     2881 gaaacctccg tatgatttca gaccgtattt ctaaaatggc tggtgcaaaa attattgaga
     2941 aacgttattc ttatcgaggt tataaaaaat atagggaatc tagtcataag tttgaattga
     3001 aacaacgtct ttattttttg atgcagcaat ctaaatagtt tgatgatttt ttagagaaag
     3061 caaagcagtt gcatgttcag attgatttta gtcaaaagca tagtcgattc atgatgacgg
     3121 atcgagcaat gacaaaacct attcgaggac gccaactcag caaacgagat ctatatgatg
     3181 aagaattttt tagaacgcat tttgctaagc aagagattga aagtcgttta gaatttttgt
     3241 tgaaccgtgt caattcttta gaagagttaa taacaaaagc aaaagaattg aatctaacca
     3301 ttgacttaaa acaaaaaaat gtaactttta tcctgaaaga aaataatcaa aagataagtt
     3361 tgggtcatca aaaaataagt gataagaaat tatatgatgt caaatttttt caagattatt
     3421 ttaaaaataa ggaagtcatt gcttcagaag gattagagaa tttacaggaa cagtaccatg
     3481 ctttccaaga agaacgagat aaggataaag tatccactga agagattgag gaagccttta
     3541 agacatttaa gaagccttta agacatttaa ggaaaaatga gataccgttc gtgaatttga
     3601 agtggaactt gcagagaacc aaatagagaa gctagttgat aagggcgtct atatcaaggt
     3661 gtctttcggt gtcaaataga gcggtcttat tttcattccc aactatcaat tggatattat
     3721 ggaagaagaa aatcataaaa aatataaagt ctacattcga gaaacgtctt cttactttgt
     3781 ctataataaa gaaaacatgg ataataattg tttcatcaag ggtaggacct taatcagaca
     3841 attgagcaac gatagccaaa aactccccta tagacgacca actttaaaaa gtcttcaaga
     3901 gaagatttct gaaattaatc ttatgattga actatctaac acgaacaaac aataccaaga
     3961 aatcaaagat gagcttgtat tagaaattgc agagattgat atgaagctag aagaaaccca
     4021 agaaaaaatc gccaccttaa acaagatggc ggaagtcctt atcaatttga agagtgaaga
     4081 tgagatcggt agaaaattag ccaggtatga cttttcaaaa ctgaacttaa cagaatcaac
     4141 ttcattagaa aatgtgaacg aagaaataag agtattgcaa gaaaacttag actattatct
     4201 ttatgagttt gagaaaagag caataagatt agaaattttt gtaagcacgt taaatatgga
     4261 aaagatgttt tcgtaatgga caaattttag aggagggata aagctagaaa tgctggatta
     4321 tgcttgattt aaggaactgc aatacatgga gcacactcat atggtttaag cacaaataat
     4381 ttttgacaat aggattaaaa aattgtaaaa taaaaataga agcgct
//
LOCUS       DAVLZS010000087         4358 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLZS010000087 DAVLZS010000000
VERSION     DAVLZS010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4358
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.087"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            109..183
                     /locus_tag="VYO88_001976"
                     /pseudo
     CDS             109..183
                     /locus_tag="VYO88_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(564..761)
                     /locus_tag="VYO88_001977"
     CDS             complement(564..761)
                     /locus_tag="VYO88_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1720009.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
     gene            complement(746..964)
                     /locus_tag="VYO88_001978"
     CDS             complement(746..964)
                     /locus_tag="VYO88_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1720010.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(1062..1847)
                     /locus_tag="VYO88_001979"
     CDS             complement(1062..1847)
                     /locus_tag="VYO88_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1720011.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(1849..2667)
                     /locus_tag="VYO88_001980"
     CDS             complement(1849..2667)
                     /locus_tag="VYO88_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1720012.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2669..3661)
                     /locus_tag="VYO88_001981"
     CDS             complement(2669..3661)
                     /locus_tag="VYO88_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1720013.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
BASE COUNT         1471 a          934 c          743 g         1210 t
ORIGIN      
        1 ttatctctcc ataaatacag tatatcattt aaaaaaattt aattcaagaa aaattaacat
       61 gcattaattt attttttagc acacattaaa aaataagatt agtactcaat gaaaatcaaa
      121 gagcaaacta ggaaactagc cgcaggttgc tcaaaacagt gttttgaggt tgtggataga
      181 actgacgaag tcagtaacca tacgcacggc aaggcgacgt tgacgtggtt tgaagagatt
      241 ttcgaagagt ataagtccaa aactttcgtt aaccgggata cattataagc acattcatac
      301 catcaaaaat agtagcaata aacttgaaca actaccagaa acacgaaaac aggcataatt
      361 gatgaaatat cagcgctatt aaacaatata aataaccgct aagaataagg cttaacggtt
      421 atcttctacc tatctatttt ttcaactcct cagtcgttta tctacctata acctaggctt
      481 tacgagtgcc ttgctctacc aactgagcta aatcggcgat tacacttaca gtatagcact
      541 ctgagaatag atgtcaagta atattattca agctttttaa tcaaaatctg acaaggattt
      601 tgcggattcc atagctgaga aaaaatctct aactttttaa agccaagacc tcgataaaag
      661 tcatttgttc gatcataatc tttattagaa ccttctgcca ctgttttgac ctgcagataa
      721 ccaacttttt tacgagcttc actctctaaa gtagcaagca attggctccc aatttttcta
      781 ccttgataag cttttttacg ccgagacaat caatctctgc acaatcttca ctcgaatagg
      841 ataaccttac aaatccagtc aaatcactct cctgataggc ggtccaaact tgcagtgtcg
      901 tggttccttc tatataggct tgtgtgcttt ctgggattcc aaaccattct ggcaaatcct
      961 tcaaaacctc agcgacaact gccttttttg attttcatcc ttgacttctt caattacaaa
     1021 catcataagt tcctttcttg attttagtct tactttagct tttacgaacc cgcactttcg
     1081 taggaatcta agcccttatc ccaaagttta agggaaataa caaagaaaac cagagaaatc
     1141 aacatcaaac ctcctacgtt aaagaacaca tccttttcct gtaagaaata gctagctgga
     1201 tagtaggctg taaaggcgaa aggcacgata aagctaatca accaacgaag aagagaattg
     1261 taaatagaaa tcggatactt agcaaagtca ttgaacatat agaagatgta aatcatggcg
     1321 cctgactgct tagtccaaaa ggcgatactg gctgttgcga ttttaagaga agtataaatc
     1381 aaggtcgcaa aaggaataca aactaggaaa agcaggaatt ttggaagagt ccaaacaatg
     1441 ctggtcactg ttgttcccaa taaaatacca ccgactaaga gttcacccaa ggcatcaatc
     1501 tgaaaggttt caactaggat atgaaagaga ggattgatgg gacgagtcag atacttgtca
     1561 aactcccctt ttcggactag gcgttgccct agtgcccaga gattgtcaaa aaagagatgg
     1621 tccattccct tgggaatcaa ggaaaatcca taaatgaaag ctatctcttg aaaggtccag
     1681 ccttctagga atggaatatg ttgaaagatg acattgagaa acaagagatt caagccttga
     1741 gccagaaaga ctcccaagac accaaccaca aaatccacct tatattccat gatttgtttg
     1801 atgtattgtc tgataaaaat cagatgcatt cgttgatatt ttttcatact aacctccttg
     1861 aatggtgata aaggactgga cccgtttcca aatcaactga gacaatccca ccatcactaa
     1921 gagccagaag aactgcaaaa ggagtgcctg aagaatctga ctggcatcgt attttccaac
     1981 aatgatcata actggagtat aaatcaagga tgaaaaaggc aaaaaggaga gaatatctga
     2041 aacaaccttt ggaaagaatg ccaagggaat caaactcccc gacataaaag ccactatgga
     2101 agtcttaagt aggttggaac cccaaagatt tttaaacaca aaggctgaaa atccaaagca
     2161 aatattaaag aaaaagttaa tcagataggc gagcgttaag ctaaaaagat aaatgacagt
     2221 taatcctagc acctctacaa taccttgacc cgatatgatt ttcatcaaga caatgacact
     2281 taaaaatgga aggccaacgc tgataaaaat caaccacttg gaaccaagct cggtgaaaag
     2341 ataggaggcc gcaaaatgca ctggtcgcaa caaacgcatg ataatggagc catccttgac
     2401 ctcctcccca atcataaagg acgaatcgga tctagtcaga agattggtca caaaactcat
     2461 gatgatgtag agggtgatat ccgccatact gaagccctga atcaaagact cttgcgaaga
     2521 atcaaagaca gccttccaga gataaaaggc cacaaaagcc cccatgacat cgccaatccg
     2581 atagagaata aagttgactc ggtaagtaat caactcctga acccctgcat tgataaaggg
     2641 tttataacgt ctccacaatt tgatcatcct agagctcctt tcggtagaag cgacggataa
     2701 tatcctcaat atccgtatcc accatcttca aatcgcggat ttcaaaatca gacagggttt
     2761 gcttgataat gtcagctgac tggtagcgag aactatcaaa ttcaatgttg aggctgtttc
     2821 cttgtctatc aatggtcata tcagacagac cttcatagtg agagacgaga tgactttgac
     2881 ctggtagcag ttcaaaagag agagtcttca tcttaccaaa ggtctccttg agttggctca
     2941 ccgttccatc aaaaatctct tgccccttgt caatcatgaa aatccgatca caaagttgct
     3001 caatatcact caaatcgtga gtggtcaaaa gaatggtagt ttcttcctct tgattgatct
     3061 gagtaattgc ccgacgaata ttatccttaa ccgaaacgtc caaaccaatg gtcggctcat
     3121 ctaaaaaaag aaccttggga ttgtggagca aggaggccgc aatatccgcc cgcatccgtt
     3181 gtcccagtga aagagtccgc acgggatcct tgataaagtc cttcaaatcc aagacttcat
     3241 tcaaaaagtc catacgctta tgaaagagcg agtctggcac atcataaatc tcttttaaga
     3301 cagtgtaggt ctcttgcaga gccaaatccc accatagctg ggtgcgttgt ccaaagacta
     3361 cgccaatatc tttgacataa tcttgccgat tgttctgggg aatcttgccg ttaatccgac
     3421 aaaaaccaga tgttggtttc aaaattcctg tcagcatttt aatggttgtc gacttcccag
     3481 caccatttgc cccgataaat cctaaaatct gcccttttgg aacctcaaag gtcaaatcct
     3541 tgaccgcttc aaaggtctgc ttttcaggat gaataaagga gcgcaaagcc cccttcaagc
     3601 ccggttcctt aacagtcttc acaaaatttt tctgaagatg ttccacttct atcattgcca
     3661 tatctatctc cctatcgtaa ggaatagcaa cattgtgttt ttaactacaa atattctaaa
     3721 tccttacttt ctacaccttc tacattttat tactacagaa ggctttatac caacctatta
     3781 tagtccaata aaaaacagaa tgcaagcgtt tgcctatgga ttgtgaaatt aggatttctc
     3841 tcatgaaata atacttttaa tcaaaaattc tgtttaatag cttaaattac caacctactc
     3901 atcttctcac cagagggcgg tattaacttt gatcataaaa tcggatactc cctctatcca
     3961 gaaaatatgc tcagaatgat tgtctctaaa caatacctgc tcttttacct cattcatgaa
     4021 aaagaagtcc ataccctgag aattatcaac tcacgcaccg actacctaaa ccaactcgac
     4081 cacctctttc gtacatgtag gaaactattt tcctcacaaa taatctcatt ataaaatcca
     4141 ataaattttt tagctcactt gaatattttc tttgtatcgt tttatcagct tcaatctgat
     4201 ctagacttgt taccttggaa cgacttgaaa taacctttat aaaataacac ttaagacttt
     4261 catcatttcg tataaatttt tcaatagtga tataaaaagc tttcatattc tgtttgtaat
     4321 cagatatcaa ttgattaatt ttatcattct gatgaaga
//
LOCUS       DAVLZS010000088         4348 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLZS010000088 DAVLZS010000000
VERSION     DAVLZS010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4348
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.088"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(1..1491)
                     /gene="lysS"
                     /locus_tag="VYO88_001982"
     CDS             complement(1..1491)
                     /gene="lysS"
                     /locus_tag="VYO88_001982"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1720014.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIVQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(1619..1765)
                     /locus_tag="VYO88_001983"
     CDS             complement(1619..1765)
                     /locus_tag="VYO88_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV1720015.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            1980..2660
                     /locus_tag="VYO88_001984"
     CDS             1980..2660
                     /locus_tag="VYO88_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1720016.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            2620..3297
                     /locus_tag="VYO88_001985"
     CDS             2620..3297
                     /locus_tag="VYO88_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1720017.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTISLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(3472..4005)
                     /locus_tag="VYO88_001986"
     CDS             complement(3472..4005)
                     /locus_tag="VYO88_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1720018.1"
                     /translation="MNNQPYLELIESEIIEFCKSNTLLNFEELSKYFKKDRRIFVGGV
                     GRSSMAARGFVNRLVHLGYSAHLIGEISTPLARKDDVVLLISNSGNTNSLYTIGERAK
                     KDGAKILSITSNKDSKIFQISDDSLVLKDVDKSNQPMGSLFEQAALLVTDAFILFLMN
                     LNIETSESMRKRHSNLE"
     gene            complement(3998..>4348)
                     /locus_tag="VYO88_001987"
     CDS             complement(3998..>4348)
                     /locus_tag="VYO88_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1720019.1"
                     /translation="EFNKKVGVAISPHTSISSIESILPFVDQVLVLTIKPGTSNSHII
                     TEMYGKIKELHDIKSIKEYSYRIMVDGKVDDKTLGPILKSGAEAVVSGGYIFKNEKIL
                     DNIEILKKIGKSYE"
BASE COUNT         1217 a          889 c          797 g         1445 t
ORIGIN      
        1 ttatttcatt gttgggaaga gcaatacatc acggatagtt gttgtatcag tgaggagcat
       61 gcagagacgg tcgataccga ttcccaaacc acctgttggt ggcataccgt attcaagagc
      121 ctcgatgtag tcatagtcga ttcctgtcgc ttcatcatca ccaagttctt tggctttagc
      181 ttgggcttca aaacggctaa gttggtcgat tgggtcgttc aactcagtaa aggcattacc
      241 gtactcctta gtcatgataa agagctcgaa acggtcagta aagcgttggt cttcaggatt
      301 tttcttagcg agtggagata cagctactgg atgtccatag acaaaggttg gttggattaa
      361 agtttcttca acaaactctt caaagaaggc attgatgatg tgaccaacct cagtgtagtg
      421 tttctcaact ggaactttct tctcagcagc gatagcttta gcttcttcca aagtcatgtc
      481 ttgccagaaa tcgacaccag taatttctct gatagcatcc accatatgaa cacgcttaaa
      541 tggttcgtta atcttgattt cagtaccttg gtagttgact gggccatcgc ccttaactga
      601 tttagcagcg tgttggacaa tgccttccgt caagtccatg atgtcttgga agtctgcata
      661 agcttggtaa acttcgatag aagtaaactc agggttatga gtagcgtcca ttccctcgtt
      721 acggaagata cggccaattt catagacacg ttccatacca cccacgataa ggcgttttaa
      781 gtgaagctca gtcgcgatac gaagcaccat gtcaatgttt tgggcattgt ggtgggtgat
      841 aaatggacgg gcagcagcac caccggcttc attatgaaga acaggtgttt ccacttcaag
      901 gaatcctttt tggtcaaggt aacgacggat ttcagagatg atttttgaac gagtgacaaa
      961 gcgttcaaag ctttcacggt tagaaatcaa gtcaaggtaa cgtttacggt aaattgtttc
     1021 aacgtctgtc aaaccatgga atttctcagg aagaggacga agagccttag acaagtgtgt
     1081 gatgtgggtt gccttgatag agagttctcc catatccgta cgcatcactt caccttcgac
     1141 accaaggaag tcaccaaggt ctgctttttt gaagatttcg tagttttctt caccgacagc
     1201 atccttacga acatagatct gaatctggcc ttcgcggtct tgaaggtggg caaaacccac
     1261 tttaccttta ccacgtttgg ttaccaagcg tcctgcgata gtagctgttt cgtttttatc
     1321 gtgtaattgt tctttatcga ggttggcata tttatctttt aattcttgtg aatttgcagt
     1381 acgttcaaaa cgttttccga aaggatcgat tccttgttcg cggagcgcag ccattttttc
     1441 acggcgaacg atctgctggt catttagttc ttccatatgt tctgtagaca tgggatcctc
     1501 ctagttttac tcaaaattga atacgatgag tcattttttg cgatactccc attttatcat
     1561 aaataagcaa gaaattcacg gataatcttt aaaaactaaa aagaacctga cgctaaaatc
     1621 actggaaaga agtgaaagta tcttccgccc cactagcgat atagccaaat gctgctttag
     1681 gaataacttg ttgcgccatt ggctccaaat cataggtatt gatgaaatct acatgacctt
     1741 ctgcattgct tgttttgtat gacataaaat gtcctcctta ataagtaagc gtttactttg
     1801 tatattataa aaatatctta actctttttc aaaacttttc aaatattttg tttggaaatt
     1861 tcagaaattt tatgtctatg gtaaaaaatc cttataacgg caataaaaaa tagatattat
     1921 ccaaagaaga ttttaagtgc tacaataact gtattatttc tagatgggag gttctatttt
     1981 tggattggtc cattgttgaa caatatctac cactatatca aaaggcattc tttctgacct
     2041 tgcatattgc agtttgggga attttgggat cctttctgct cggtttaatc gttagtatca
     2101 tccgacatta tcgaatccct gttttggcgc aagtagcgac agcctacatt gaattgtcac
     2161 gtaatactcc ccttttgatt caactcttct ttctctactt cggtcttccc cgaatcggga
     2221 ttgtcctatc ttcagaagtc tgtgcaacgc ttgggcttgt ctttttagga ggctcctata
     2281 tggcagaatc tttccgaagt gggctggaag ccatcagtca aacccagcag gagattggcc
     2341 tcgctattgg tctgacacct ctacaggtct tttactatgt ggttcttccg caagcaacag
     2401 cggtggcact cccctccttt agtgccaatg tcattttcct tatcaaggaa acctctgttt
     2461 tctcagcagt ggctttggcc gacctcatgt acgtcgccaa ggatttgatt ggtctctact
     2521 atgagacaga cattgcgcta gctatgttgg tagttgctta tctgatcatg ctgctaccca
     2581 tctcactggt ctttagctgg atagaaagga ggacccgcca tgcaggattc gggaatccaa
     2641 gtactctttc aaggaaataa tctcctgaga atcttacagg ggttgggcgt tacgattggg
     2701 atatccatcc tgtctgtcct cttatccatg atgttcggaa cagtcatggg aatcatcatg
     2761 acctcccatt ctagaatcat acgattttta acacgattgt atctggactt tatccgtatc
     2821 atgccccagc tggtgctact cttcatcgtt tactttggct tggctcgaaa ctttaatatc
     2881 aatatctcag gtgagacttc agctattatc gtttttaccc tctggggaac agctgaaatg
     2941 ggagacttgg tacgtggagc tatcacttct ctccctaaac atcagtttga aagtggacag
     3001 gcactcggct tgactaatgt tcaactttac taccacatca tcatcccaca agtcttaaga
     3061 agactgctac cgcaggctat caatcttgtc actcggatga ttaaaaccat ttcattagtt
     3121 gttttgattg gggttgtgga agtgaccaaa gttggacaac aaatcatcga tagcaatcgc
     3181 ctgaccatcc caactgcttc attttggatt tatggaacca ttctagtctt atatttcgca
     3241 gtttgctacc ctatttccaa actatccact cacttagaaa aacattggag aaactaaatg
     3301 tctgaaacta tcttagaaat caaggaacta aaaaaatagg gttgcccgtc gacaaccctt
     3361 ttaaaatttc accatagata aagttatgta aatcgaataa tttgtttgat aaattactat
     3421 aatttattaa tcttaaacaa cgatatattc tagcataaga taagatttgt atcactccaa
     3481 atttgaatgt cttttcctca ttgattcaga tgtttctatg tttagattca ttagaaacaa
     3541 aatgaaagca tcagtcacaa gcaaagctgc ttgttcaaat aaactaccca taggctgatt
     3601 tgatttatca acatccttta ataccaatga atcatcgcta atttgaaaaa ttttagaatc
     3661 tttattggat gttatactta atattttagc tccatctttt tttgcccttt ctcctatggt
     3721 atacaatgaa tttgtatttc ctgaattaga tataagtaat acaacatcat cttttctagc
     3781 taaaggagtg ctaatctctc ctattaaatg tgcagagtat cctaaatgaa caagtctatt
     3841 tacgaatcct cttgctgcca tacttgatct tccgacacca ccaacgaata tccttctatc
     3901 tttcttaaaa tatttagata attcttcaaa atttaagaga gtatttgatt tgcaaaactc
     3961 aataatttcg ctctctatta attccaagta aggctgatta ttcataactt tttcctatct
     4021 tttttaatat ttcaatgttg tctaatattt tttcattttt aaaaatatat ccaccagata
     4081 caacagcctc agcaccgctt tttagtattg gtccaagtgt tttatcatca acttttccat
     4141 ctaccataat cctatatgag tattctttta tactttttat atcatgtaat tccttaattt
     4201 taccatacat ttcagtaatt atatgggaat ttgaagtacc aggctttatc gttaaaacta
     4261 aaacttgatc tacaaaaggt aaaatagatt ctatgcttga tattgatgta tgtggactaa
     4321 tagctactcc aactttttta ttgaattc
//
LOCUS       DAVLZS010000089         4176 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLZS010000089 DAVLZS010000000
VERSION     DAVLZS010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.089"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="VYO88_001988"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="VYO88_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1720020.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1320..2024
                     /locus_tag="VYO88_001989"
     CDS             1320..2024
                     /locus_tag="VYO88_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1720021.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2017..3366
                     /gene="vicK"
                     /locus_tag="VYO88_001990"
     CDS             2017..3366
                     /gene="vicK"
                     /locus_tag="VYO88_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1720022.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3368..>4176
                     /locus_tag="VYO88_001991"
     CDS             3368..>4176
                     /locus_tag="VYO88_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1720023.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
BASE COUNT         1253 a          743 c          968 g         1212 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat tcctggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gtctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccgg atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctttggtccc agtccagaag agagtttcca
     1021 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgcacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttt ggtataatag tagagaaaaa ggtgaacata
     1321 tgaaaaaaat actaattgta gatgatgaga aaccaatctc ggatattatc aagtttaata
     1381 tgaccaagga aggttacgaa gttgtaactg cttttaatgg tcgtgaagca ctagagcaat
     1441 ttgaagcaga gcaaccagat attattattc tggatttgat gcttccagaa attgatggtt
     1501 tagaagttgc taagaccatt cgtaagacaa gcagtgtgcc cattcttatg ctttcagcca
     1561 aagatagtga atttgataag gttatcggtt tggaacttgg ggcagatgac tatgtaacga
     1621 aacccttctc caatcgtgag ttgcaggcgc gtgttaaagc tcttctgcgt cgttctcaac
     1681 ctatgccagt agatggtcag gaagcagata gtaaacctca acctatccaa attggggatt
     1741 tagaaattgt tccagacgcc tacgtggcta aaaaatatgg cgaagaacta gacttaaccc
     1801 atcgtgaatt tgagcttttg tatcatttag catcgcatac aggtcaagtc atcacgcgcg
     1861 aacacttgct tgagactgtc tggggttatg actattttgg tgatgtccgt acagttgatg
     1921 tgactgtacg acgtctgcgt gagaagattg aagatacgcc cagccgacca gagtatatct
     1981 tgacgcgccg tggtgtaggg tattacatga gaaataatgc ttgatttact gaaacaaacc
     2041 atttttacca gagattttat ctttatcctg attttgttag gtttcatcct tgttgtgacc
     2101 ctcttattac tggaaaatag acgtgataat attcagttga agcaaatcaa tcaaaaggtt
     2161 aaagatttga ttgcaggaga ttattccaag gttcttgata tgcaaggtgg gtctgaaatc
     2221 accaatatta ccaataattt gaatgacttg tcggaggtta ttcgtctcac tcaggaaaat
     2281 ctagaacaag agagtaagag gctaaatagt attctgtttt atatgacaga tggggttctt
     2341 gcgaccaacc gtcggggtca gattatcatg attaacgata cagccaagaa gcaactgggg
     2401 ttggttaagg aagatgttct gaatagaagc attttggaat tgctcaagat agaagaaaac
     2461 tatgaattgc gtgatttgat tacccaaagt ccagaattgt tgctagattc ccaagatatc
     2521 aatggtgaat atttgaacct tcgagttcgc tttgccttga tacgtcgaga gtctggcttt
     2581 atttcaggtt tggtggctgt tttgcatgat acgacggagc aggagaagga agaacgcgaa
     2641 cgaagactct ttgtttccaa tgttagccat gagttacgga ctcctctgac tagcgtaaaa
     2701 tcctatcttg aagccttgga tgagggggct ttgtgtgaaa ctgtagcacc agactttatc
     2761 aaggtttctc ttgatgagac caaccgtatg atgcgcatgg tgacggatct cctccatctt
     2821 tcacgtattg ataatgctac cagtcaccta gatgtggaac tgattaactt cactgctttt
     2881 attaccttta tcctcaatcg ttttgacaag atgaaaggac aggaaaagga gaaaaaatat
     2941 gagttggtga gagattatcc catcaattct atctggatgg aaattgatac agataagatg
     3001 acgcaggttg tcgacaatat tttaaataat gctattaagt attcgccaga tgggggtaaa
     3061 atcactgtca gaatgaagac aactgaagac cagatgattt tatccatttc tgaccacggt
     3121 ttggggattc ctaagcagga tttaccacgt atctttgacc gtttctatcg tgtggatcgt
     3181 gctagaagtc gtgcacaagg tggtacaggt ctaggactgt ctatcgctaa agaaattatc
     3241 aaacaacata agggctttat ttgggccaag agtgaatacg gcaagggttc aacctttacc
     3301 attgtgctcc cttatgataa ggatgcagtg aaagaagaag tatgggagga tgaagtagaa
     3361 gactagaatg agtgaaatag gctttaaata cagtatttta gcgtcgggtt ccagtggaaa
     3421 ttctttttat ctggaaacct caaaaaagaa gcttttagta gatgcaggct tgtctggcaa
     3481 gaaaattacc agtctgctag ctgaaattaa ccgtaagcca gaagacctgg atgccatctt
     3541 gattacccat gagcattcag atcatatcca tggagtaggc gttttggctc gcaagtatgg
     3601 tatggatctt tatgccaatg aaaagacctg gcaagctatg gaaaatagta aatatcttgg
     3661 caaggtggat tcttcgcaaa agcatatttt tgaaatgggt aaaaccaaaa cctttggaga
     3721 tatcgacatc gagagttttg gtgtaagcca tgatgcagtc gcaccgcagt tctatcgctt
     3781 tatgaaggat gataagagtt ttgtcctttt gacagataca ggttatgtca gtgaccgtat
     3841 ggcgggcatt gtcgaaaatg cggatggcta tcttatcgag gccaaccatg atgtagagat
     3901 tttgcgatca ggttcttacg cttggcgact caaacaacga atcctatctg accttggtca
     3961 cctttctaac gaggacggtg ctgaagctat gattcggacg ctaggaaatc gtactaagaa
     4021 gatttacctt gggcatttat ctaaggaaaa caatatcaag gaactggctc atatgaccat
     4081 ggtcaatcag ctggctcaag ctgatctggg agtcggagta gactttaagg tttatgatac
     4141 ctcaccagat accgcaacac cattgacaga gatata
//
LOCUS       DAVLZS010000090         4112 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLZS010000090 DAVLZS010000000
VERSION     DAVLZS010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.090"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..746
                     /locus_tag="VYO88_001992"
     CDS             <1..746
                     /locus_tag="VYO88_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1720024.1"
                     /translation="STDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVK
                     NGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFG
                     NASDHVRKNKADQDSKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYKPSTDTE
                     ETEEEAEDTTDEAEIPQVEHSVINAKIAEAETLLEKVTDSSIRQNAVETLTGLKSSLL
                     LGTKDNNTISAEVDSLLALLKESQPTPIQ"
     gene            956..4075
                     /gene="phtE"
                     /locus_tag="VYO88_001993"
     CDS             956..4075
                     /gene="phtE"
                     /locus_tag="VYO88_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1720025.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSISKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1521 a          686 c          816 g         1089 t
ORIGIN      
        1 cttcgacaga ccatcaggat tcaggaaata ctgaggcaaa aggagcagaa gctatctaca
       61 accgcgtgaa agcagctaag aaggtgccac ttgatcgtat gccttacaat cttcaatata
      121 ctgtagaagt caaaaacggt agtttaatca tacctcatta tgaccattac cataacatca
      181 aatttgagtg gtttgacgaa ggcctttatg aggcacctaa ggggtatagt cttgaggatc
      241 ttttggcgac tgtcaagtac tatgtcgaac atccaaacga acgtccgcat tcagataatg
      301 gttttggtaa cgctagcgac catgttcgta aaaataaggc agaccaagac agtaaacctg
      361 aggaagataa ggaacatgat gaagtaagtg agccaactca ccctgaatct gatgaaaaag
      421 agaatcacgc tggtttaaat ccttcagcag ataatcttta taaaccaagc actgatacgg
      481 aagagacaga ggaagaagct gaagatacta cagatgaggc tgaaattcct caagtagagc
      541 attctgttat taacgctaag atagcagagg cggagacctt gctagaaaaa gtaacagatt
      601 ctagtattag acaaaatgct gtggagacat tgactggtct aaaaagtagt cttcttctcg
      661 gaacgaaaga taataacact atttcagcag aagtagatag tctcttggct ttgttaaaag
      721 aaagtcaacc gactcctata cagtagtaaa atgaatggag catattttat ggagaagtaa
      781 cctttcgtgt tacttctctt ttttagaaaa acgtaacaga aacttgacaa aagtaatttt
      841 aaatagtaaa ctatttactg gttaattaaa tggttaaata accggtttag aaaactattt
      901 aataaagtaa aagaagttga gaaaaaactt catcatttat tgaaatgagg gatttatgaa
      961 atttagtaaa aaatatatag cagctggatc agctgttatc gtatccttga gtttatgtgc
     1021 ctatgcacta aaccagcatc gttcgcagga aaataaggac aataatcgtg tctcttatgt
     1081 ggatggcagc cagtcaagtc agaaaagtga aaacttgaca ccagaccagg ttagccagaa
     1141 agaaggaatt caggctgagc aaattgtaat caaaattaca gatcagggct atgtaacgtc
     1201 acacggtgac cactatcatt actataatgg gaaagttcct tatgatgccc tctttagtga
     1261 agaactcttg atgaaggatc caaactatca acttaaagac gctgatattg tcaatgaagt
     1321 caagggtggt tatatcatca aggtcgatgg aaaatattat gtctacctga aagatgcagc
     1381 tcatgctgat aatgttcgaa ctaaagatga aatcaatcgt caaaaacaag aacatgtcaa
     1441 agataatgag aaggttaact ctaatgttgc tgtagcaagg tctcagggac gatatacgac
     1501 aaatgatggt tatgtcttta atccagctga tattatcgaa gatacgggta atgcttatat
     1561 cgttcctcat ggaggtcact atcactacat tcccaaaagc gatttatctg ctagtgaatt
     1621 agcagcagct aaagcacatc tggctggaaa aaatatgcaa ccgagtcagt taagctattc
     1681 ttcaacagct agtgacaata acacgcaatc tgtagcaaaa ggatcaatta gcaagccagc
     1741 aaataaatct gaaaatctcc agagtctttt gaaggaactc tatgattcac ctagcgccca
     1801 acgttacagt gaatcagatg gcctggtctt tgaccctgct aagattatca gtcgtacacc
     1861 aaatggagtt gcgattccgc atggcgacca ttaccacttt attccttaca gcaagctttc
     1921 tgccttagaa gaaaagattg ccagaatggt gcctatcagt ggaactggtt ctacagtttc
     1981 tacaaatgca aaacctaatg aagtagtgtc tagtctaggc agtctttcaa gcaatccttc
     2041 ttctttaacg acaagtaagg agctctcttc agcatctgat ggttatattt ttaatccaaa
     2101 agatatcgtt gaagaaacgg ctacagctta tattgtaaga catggtgatc atttccatta
     2161 cattccaaaa tcaaatcaaa ttgggcaacc gactcttcca aacaatagtc tagcaacacc
     2221 ttctccatct cttccaatca atccaggaac ttcacatgag aaacatgaag aagatggata
     2281 cggatttgat gctaatcgta ttatcgctga agatgaatca ggttttgtca tgagtcacgg
     2341 agaccacaat cattatttct tcaagaagga cttgacagaa gagcaaatta aggctgcgca
     2401 aaaacattta gaggaagtta aaactagtca taatggatta gattctttgt catctcatga
     2461 acaggattat ccaagtaatg ccaaagaaat gaaagattta gataaaaaaa tcgaagaaaa
     2521 aattgctggc attatgaaac aatatggtgt caaacgtgaa agtattgtcg tgaataaaga
     2581 aaaaaatgcg attatttatc cgcatggaga tcaccatcat gcagatccga ttgatgaaca
     2641 taaaccggtt ggaattggtc attctcacag taactatgaa ctgtttaaac ccgaagaagg
     2701 agttgctaaa aaagaaggga ataaagttta tactggagaa gaattaacga atgttgttaa
     2761 tttgttaaaa aatagtacgt ttaataatca aaactttact ctagccaatg gtcaaaaacg
     2821 cgtttctttt agttttccgc ctgaattgga gaaaaaatta ggtatcaata tgctagtaaa
     2881 attaataaca ccagatggaa aagtattgga gaaagtatct ggtaaagtat ttggagaagg
     2941 agtagggaat attgcaaact ttgaattaga tcaaccttat ttaccaggac aaacatttaa
     3001 gtatactatc gcttcaaaag attatccaga agtaagttat gatggtacat ttacagttcc
     3061 aacctcttta gcttacaaaa tggccagtca aacgattttc tatcctttcc atgcagggga
     3121 tacttattta agagtgaacc ctcaatttgc agtgcctaaa ggaactgatg ctttagtcag
     3181 agtgtttgat gaatttcatg gaaatgctta tttagaaaat aactataaag ttggtgaaat
     3241 caaattaccg attccgaaat taaaccaagg aacaaccaga acggccggaa ataaaattcc
     3301 tgtaaccttc atggcaaatg cttatttgga caatcaatcg acttatattg tggaagtacc
     3361 tatcttggaa aaagaaaatc aaactgataa accaagtatt ctaccacaat ttaaaaggaa
     3421 taaagcacaa gaaaactcaa aacttgatga aaaggtagaa gaaccaaaga ctagtgagaa
     3481 ggtagaaaaa gaaaaacttt ctgaaactgg gaatagtact agtaattcaa cgttagaaga
     3541 agttcctaca gtggatcctg tacaagaaaa agtagcaaaa tttgctgaaa gttatgggat
     3601 gaagctagaa aatgtcttgt ttaatatgga cggaacaatt gaattatatt taccatcggg
     3661 agaagtcatt aaaaagaata tggcagattt tacaggagaa gcacctcaag gaaatggtga
     3721 aaataaacca tctgaaaatg gaaaagtatc tactggaaca gttgagaacc aaccaacaga
     3781 aaataaacca gcagattctt taccagaggc accaaacgaa aaacctgtaa aaccagaaaa
     3841 ctcaacggat aatggaatgt tgaatccaga agggaatgtg gggagtgacc ctatgttaga
     3901 tccagcatta gaggaagctc cagcagtaga tcctgtacaa gaaaaattag aaaaatttac
     3961 agctagttac ggattaggct tagatagtgt tatattcaat atggatggaa cgattgaatt
     4021 aagattgcca agtggagaag ttataaaaaa gaatttatct gatctcatag cgtaaggaat
     4081 agcagtagaa aaagtctgaa tcaaaaatga ag
//
LOCUS       DAVLZS010000091         4085 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLZS010000091 DAVLZS010000000
VERSION     DAVLZS010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.091"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            170..370
                     /locus_tag="VYO88_001994"
     CDS             170..370
                     /locus_tag="VYO88_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720026.1"
                     /translation="MVVSASASSTSPQAQEQVDKSELRALSQELDQHLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            395..811
                     /locus_tag="VYO88_001995"
     CDS             395..811
                     /locus_tag="VYO88_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720027.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1042..1749
                     /gene="ccdA2"
                     /locus_tag="VYO88_001996"
     CDS             1042..1749
                     /gene="ccdA2"
                     /locus_tag="VYO88_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1720028.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1760..2317
                     /gene="sdbB"
                     /locus_tag="VYO88_001997"
     CDS             1760..2317
                     /gene="sdbB"
                     /locus_tag="VYO88_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1720029.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2691..4082
                     /locus_tag="VYO88_001998"
     CDS             2691..4082
                     /locus_tag="VYO88_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1720030.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASAWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
BASE COUNT         1189 a          743 c          861 g         1292 t
ORIGIN      
        1 gtaaaatgaa ataagaatag gataaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ccatatgtac tattctagtt tcaatatacc ataactgctc ctagtcaacc
      121 tgcaagtcct gtcccagctc caagctcagc tccgactcaa gatcctagag tggtagtaag
      181 cgcttcggct agctcaacga gcccacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagttag accaacactt gaaagctttg gcaacagtat ctgatccgaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgccttgg actctctcaa
      421 agatgtgaaa gcaaatgcta gcgacagcaa gcctgcacag gacaagaagg atgcaaaaca
      481 aggaacggaa gatagtaagg attcagataa gatgactgaa acaaactcag ttccagcagg
      541 agtgattgtg gtcagtctac ttgccctcct aggcgtgatt gccttctggc tgattcgccg
      601 taagaaagag tcagaaatcc agcaattaag cacggaatta atcaaggttc taggacagct
      661 agatgcagaa aaagcggata aaaaagtcct tgccaaagcc caaaaccttc tccaagaaac
      721 ccttgatttc gtgaaagaag aaaatggctc agcagagaca gaaactaaac tagtagagga
      781 gcttaaagca atccttgaca aactcaagta aaacatgatt tatgaaatgt cagacttaaa
      841 agacattttc gttcacaaaa gcagcgacga gtaatccttg tcgttgcttt ttggctattt
      901 tgggggataa gatccgcctt gactagcaaa agaaaagatt ggtccaatag tgcccgatac
      961 gattttgcgt agcagaaagc ttacaaataa aattgaatat agtaaaatag gattagaatt
     1021 attaagaaag ttggttcttt attggaaacg atagtatttt taatctctgt ttttctagca
     1081 ggtgttttat cctttttttc tccttgtatt tttcctcttc tgccagtcta tgctgggatt
     1141 ttattggatg atcaagaaag tgcaaaaagc ttttctttgt ttgggagaaa ggttctctgg
     1201 tcaggcttga ttcgaacact ttgctttatc gctggtatct ctctcatttt ctttattcta
     1261 ggctttggtg ctggttactt tggtcatatt ctctatgcaa attggtttcg atatgtcatg
     1321 ggagctatta ttatcatttt gggtcttcac cagatggaaa tttttcattt gaagaaatta
     1381 gaagttcaaa aaagttttac ctttaaaaaa tcagattcta atcgttattg gtcagctttt
     1441 ttacttggta ttacctttag ctttggttgg acaccttgta ttggtccagt tttaagttct
     1501 gttttagcac ttgcggcttc tggaggcaat ggtgcttggc aaggagcgat ttatactctc
     1561 atttacactc tgggcatggc ccttcctttc ttggtcttgg cactagcttc aggtctagtc
     1621 atgccatatt ttagtaaaat caagcgtcat atgatgctac taaagaaaat tggtggtttc
     1681 ctcattgttt taatgggaat tttgttacta ttaggacaag taaatgttct agctggaatt
     1741 tttgaataaa ggaggacaaa tgaaaaaagt aatgtttgct ggcttaagtc tcttgtcatt
     1801 agttgtattg atggcctgtg gtgaggaaga aactaaaaag actcaagcag cacaacagcc
     1861 aaaacaacaa acgactgtac aacaaatttc tgttggaaaa gatgctccag actttacatt
     1921 gcaatccatg gatggcaaag aagttaagtt atctgatttt aagggtaaaa aggtttactt
     1981 gaagttttgg gcttcatggt gtggtccatg caagaaaagt atgccagagt tgatggaact
     2041 agcggcgaaa ccagatcgtg atttcgaaat tcttactgtc attgcaccag gaattcaagg
     2101 tgaaaaaact gttgagcaat tcccacaatg gttccaggaa caaggatata aggatatccc
     2161 agttctttat gataccaaag caaccacctt ccaagcttat caaattcgaa gcattcctac
     2221 agaatattta attgatagcc aaggaaagat tggaaagatt caatttggtg ctatcagtaa
     2281 tgcggatgca gaagcagcat ttaaagaaat gaactagaat cgataaaatc tgattacaag
     2341 atgtagtcag attttggtaa cttctaaaac taacttccag tttcccacaa cctagctttt
     2401 agtatgagaa aaacgcgtga catcagtgga aatccgtctt agactaactt ccactggttt
     2461 tctttttctt gatatataag ggttcaaaag cgaaaaaact cagaaaaagt gcacgacaaa
     2521 tagccctaaa acagagtcgt cttagagtaa cttccagttt tgggagagag atggaagtta
     2581 ctttgagaag ttacggtagt cagatttttt tagaaaaaca ttttataaat attcacatat
     2641 ctcctatatt tatggtaaaa tagaattatc agtttatttt ggagtcaaag atgaatatat
     2701 ttagaacaaa gaatgttagt ttagataaaa cagagatgca taggcatttg aagttatggg
     2761 atttgatttt gctgggtatc ggagccatgg tagggacagg cgtctttaca atcacaggta
     2821 ctgcagctgc aacacttgct ggcccagccc tagtgatttc aatcgttatt tctgccttgt
     2881 gtgtgggatt atcagccctc ttttttgcag aatttgcctc gcgagtaccc gctacaggag
     2941 gtgcctatag ttacctctat gctatcttag gagaattccc tgcctggttg gctggttggt
     3001 taaccatgat ggagttcatg acagccatat caggcgtagc ttcggcttgg gcagcttatt
     3061 ttaaaggctt gctctctcaa tacgggatag cctttcctca ggctttaaat ggtaccttta
     3121 atcctcaagc agggacattt gttgatttat tgcctattct tgtcttggtc ttggtgactt
     3181 cgcttgtttt actaaatgcc aaggcagcct tacgctttaa ttcgattcta gttattttga
     3241 aattttccgc tttagctctc tttgttttag taggaatttg gaatattaag tttgataatt
     3301 ggagcaattt tgctccttac ggttttggac aaatctatgg agctagtact ggtattatgg
     3361 ctggtgcatc cttgatgttc ttcggttttt tgggatttga atccatctct atggctgtag
     3421 atgaagtcaa gactcctcaa aaaaatattc ctagagggat tgtcttatcg ctttctatcg
     3481 taaccattct ctatgccttg gtgacccttg ttttgactgg tgtggttcac tatagtcatt
     3541 taaatgtcga tgatgccgtt gcctttgccc ttcgtagtgt tgggattagt tgggcagcca
     3601 actatgtgtc attagtggct atcttgacct tgattacagt ttgtatttcg atgacctatg
     3661 ccctatcgcg tatgatttac agtttagcac gtgacggctt agtgcctgct gcctttaagg
     3721 aactgacgaa gactagcaag gtaccaaaga atgctactat cttgacaggt ctagcttcag
     3781 cagtagcagc aggaatgttc ccactagcca gtattgcagc ctttttaaat atttgtacct
     3841 tagcctactt gatcatgttg gcttatggtc tgattcgctt acggaaagaa aaaggaatgc
     3901 ccaaagctgg ggaatttaaa acaccattgg tacctctgtt accaatttta tcgatcatca
     3961 tttgtttatc cttcatgtta cagtataata tgaatacctg gattgctttc ctagttgcgt
     4021 tgttagtagg aagtattatt tacttcactt atggctataa gcattctacc atagaagaat
     4081 aaagt
//
LOCUS       DAVLZS010000092         4074 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLZS010000092 DAVLZS010000000
VERSION     DAVLZS010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.092"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(122..442)
                     /locus_tag="VYO88_001999"
     CDS             complement(122..442)
                     /locus_tag="VYO88_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1720031.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            1199..1579
                     /locus_tag="VYO88_002000"
     CDS             1199..1579
                     /locus_tag="VYO88_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEV1720032.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGGVGCNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            complement(1996..2844)
                     /locus_tag="VYO88_002001"
     CDS             complement(1996..2844)
                     /locus_tag="VYO88_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1720033.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVETHY"
     gene            3310..3648
                     /locus_tag="VYO88_002002"
     CDS             3310..3648
                     /locus_tag="VYO88_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1720034.1"
                     /translation="MLKKYPCTIQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKIKGTRITK"
     gene            3674..>4074
                     /locus_tag="VYO88_002003"
     CDS             3674..>4074
                     /locus_tag="VYO88_002003"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720035.1"
                     /translation="MMYLDGGGYLSKSACQGICAALAMSPGTFIALTGAAVLTKKLIN
                     YIKVGGLGGWLIGAAAGVLALIFLIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLD
                     LMVYIFLGYVLVIQKDVYLFSILIIFSNFSVP"
BASE COUNT         1280 a          552 c          834 g         1408 t
ORIGIN      
        1 tcatatggga ctttttttct acacaaaata ggctccataa tatccatagg ggggttaccc
       61 actacaaata ttatagagcc acaaataata tgtaaagagt cgaggaaatc cctcggcttt
      121 tttatctttc cttcgcttgg taatagatct ctacttcttt tttgagatga gacagcatag
      181 aagtttcctc ggtcagctct aggagtgaga accctttttg gataagtttc gcatcatccc
      241 tacaaatccc aatgcggaca tagcagatag ccagcctatc gtagcttttc ttattcttgg
      301 cgtcctccag taaagtgtag cagatttgct tacacatgtt tttatcttga ttgtatagat
      361 agagtgtgga aaggttgagc aggattgcta ttcgcaagtc atataaatgt tgatagtttt
      421 tatagacttc taagcgttgc aagattttct cggattattg acaaataaac ggacattctg
      481 atagacgatt gccctagcgg cttagtgtaa actttacaaa tttggcttgt aattttttta
      541 taaaattcac tttagttact tgacagttat tatattttcg ctcataatat agataaaagg
      601 atgggatagg agtttaaaaa tttgaaagcg ctatccataa tcataacgca taattttctc
      661 cttttcgtga aaaaagttaa cgtaattttg aaatgagctt aataagaggt actatgtagg
      721 tagaaaataa agataggaga aaaagtatga ataaaaaaat attttgtatt ctagtatgta
      781 ttatatcatt gattagtcta gctatagtct ttccatgggg ctggtcgata taatgtaagg
      841 gagcttgagt tgttagtgga ggataaaatg ttaagagtaa tagtagttat tcaatcttta
      901 gtaataatac tgcttgctgt tgctttatta ttatctcgga aaaactttga ttcgttaaat
      961 gttgttctta taatgatgat cgtatcacaa ttgttgttat tagtatattt gataaaatca
     1021 gggaatcagt gattagctgt tatttgaatt aagtaaactg ttaagcttca agcagtaact
     1081 ggttttaaat atttaaaata agataaagga aggaagtcta atttaggtaa ctaaacaaag
     1141 cctgcgatca cttgttagga aaccatccta accatgctta ataaaaagga gaaaacaaat
     1201 ggaacttgta ttaccaaata attatgttgt gattgatgaa gaagagatga tgtaccttga
     1261 tgggggtggt gttggttgta actggtggaa tagtagaggt agttttgcaa cagttctgga
     1321 tgtaggtttg gccatctata gtggtggtgc aacaatttat tctgcttatg cgataaaaaa
     1381 agctatctca gctaatagag gggctattac gagaacatta cgtagtttaa taattaaaca
     1441 tgtaggtagt gcagctggcc atttagtcaa tactgcacta aacgttgcac taactgttac
     1501 tggattttca ctaggtggag caatcgcata tggggctgat tgggctgacg gtagcttaga
     1561 tggttatatt tttgcttaaa atgaaacatt tttttgcagg aattggtgaa ataaactttg
     1621 taagttattt attgtatata tgtgtaggaa tagccccttt ttttcacgta tatataatag
     1681 gttctgaaat gaattttgtg aaaatagtgt tatctatttt gggaattata tttgtttgta
     1741 ttttaactat tgctcgaatt tataggactt ttttctataa agaatagttt ggacttgaaa
     1801 tgtatttaaa aacaagaggt tggtagatta tcagcctctt tcttgtcgtt gaaaaagtga
     1861 gatatattga cttttgaaaa aaatgtcata attgagttgg gataaacgta aaagtcatac
     1921 tttctcgtta aatcgttcgg cgattctatg aaaaggtcga ggagctccct cgaccttttt
     1981 ttataatttc tttggttaat aatgggtctc tacttctttt ttgagatgag acagcataga
     2041 agtttcctcg gtcagctcca gaagggagaa ccctttttgg ataagtttag aatcgtctgt
     2101 acaaatccca atgcggacat agcagatagc cagcctatcg tagcttttct tattcttggc
     2161 gtcctctagt aaagtgtagc agatttgctt acacatgttt ttatcttgat tgtatagata
     2221 gagtgtggaa aggttgagca ggattgctat tcgcaagtca tataaatgtt gatagttttt
     2281 atagacttct aagcgttgca agatttttcc agtgatgaga tggaggtatt caatgggaaa
     2341 actgaaaaga atggtattga ggatttttag atcactctca taccatgtat cttgtttttc
     2401 aatttttctc caaagttttt tgacaacctg ttctgcgtga tctgatagtt cccctgcccc
     2461 gtgttgacgg atataaatga caacttcaag catatctctg atttcttcta tagggagatc
     2521 gtggtgggtc ttgaggtagt cttggcattt ttgaaataaa ttgacaagat cgctggtccc
     2581 gataatggaa cgcatattga gataggtttg cataatctct gtgcgttgac ttggttgata
     2641 aagttgacag atatattcaa actcttcaaa actcatattg atttgacgga gaagaaattc
     2701 catattttca tattttgggg ttgtcttgcc actttcgatt tttgataagc tggttcttga
     2761 gagaacaccc ccacagacct cttcttgggt cagccccttt gactcacgta tttctttata
     2821 gacctttccg aaatcataac gcatgatttt ctcctttctg tgaaaaaagt taacaaataa
     2881 taaaatcttg ttaaaaatat tgtatcatag caatgtaaaa agtaaaaaag aaagtcgaaa
     2941 taaatttgtg aaaaaagtta acgtaatttt aaaatgagct taataagagg tatgatgtag
     3001 gtagaaaata aagataggag aaaaagtatg aataaaaaaa tattttgtat tctagtatgt
     3061 atgatatcat tgattagtct ggccataatc tttccatggg gctggtcgat ataatgtaag
     3121 ggagcttgag ttgttaaagg aggcttagtc cttggacaaa aatctgctgt actacaatgc
     3181 ttggaaagat atcaagaaca aagaatgata cgattgaaac taaactgatt caagaactac
     3241 tgggcagtga ttgaggtttg ggtgacatca aagaaaagtt agattaattc taaagaattg
     3301 agtatttcta tgttaaaaaa atatccttgt acgattcaac atgatcagtc agattgtgct
     3361 gcggcagttg tttcaacagt tcttttatct tacaaaaagg aactatcaat catgaagatt
     3421 cgggaaatta ttggtacaga catgtatgga acgactgtca gtggtattgt ttcaggtctg
     3481 aataagttga attttacagt aaaagctgtt cgagtagcac tggaagattt gactccaaaa
     3541 ttaacatttc ctgcgattct tcaagttaag aatgatttag gtcaaaatca ttttgtggta
     3601 ttacatagta taaaggagaa aataaaggga actcgtatta ccaaataatt atgttgctct
     3661 tgagcaagag gagatgatgt atcttgatgg ggggggttat ttaagcaaga gtgcttgtca
     3721 aggaatttgc gcagctttag ctatgagtcc aggaactttt atagcattga ctggagctgc
     3781 agttttaaca aaaaaactaa taaactatat taaggttgga ggccttggag gttggcttat
     3841 tggtgcagca gcaggtgtat tggctcttat ctttttgata aaaatttgtg tagatactac
     3901 gataaaggtt ctattaaaca gaatctttaa ggcaagtaag gtaatgaaaa ggaggatatt
     3961 ttctcttttt gtactagatt tgatggtcta tatattttta ggttatgttt tagtgataca
     4021 aaaagacgta tatctgtttt caattctgat aattttttct aatttttcag ttcc
//
LOCUS       DAVLZS010000093         3693 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLZS010000093 DAVLZS010000000
VERSION     DAVLZS010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.093"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..302
                     /locus_tag="VYO88_002004"
     CDS             <1..302
                     /locus_tag="VYO88_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720036.1"
                     /translation="IFSMLMLMLVIHLLGDIWTVKLMLVNNHKYVDHILFRTVKHPNY
                     FLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEEKLLHEVIIPNGSIKR"
     gene            402..533
                     /locus_tag="VYO88_002005"
                     /pseudo
     CDS             402..533
                     /locus_tag="VYO88_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            580..3234
                     /gene="pspC"
                     /locus_tag="VYO88_002006"
     CDS             580..3234
                     /gene="pspC"
                     /locus_tag="VYO88_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV1720037.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEEVGGRN
                     TPTVTSSGQDLSKKYADEVESHLKKILSEIQTQLDRKRHTKTVALINELQDIKKTYLY
                     NLNVLKEKSKAELPSKIKAKLDVAFEQFKKDTLKPGEKVAEAEKKVEEAKKKAKAQKE
                     EDFRNYPTNTYKTLELEIAESDVKVKEAELELVNEEVKEPLNEGTIKQAKEKVESEKA
                     EAIRLEEIKTDRKKAEATRLEKIKTDRKKAEEEEAKRQADAKEQEKPKRRAKRGVPGV
                     LATPDKKENDAKSSDSSVGEETLPSPSLNMANKSQTEHRKAAKQVDEYIEKMLSEIQL
                     DKRKHTQNFALNIKLSRIKTEYLYGLKEKSEAELPSKIKEKLDAAFEQFKKEPELTKK
                     VAEAKQKAEEAEKKAKAQKEEDFRNYPTNTYKTLELEIAESDVKVKEAELELVKEEAK
                     EHRNEEKIKQVKAKVESKKAEATRLEKIKTDRKKAAEAKRKAAEAEKKAAEAKPKVDA
                     EEYALEAKIAELEYEVQRLEKELKEIDESDSEDYVKEGLCAPLQSKLDTKKAKLSKLE
                     ELSDKIDELDAEIAKLEDQLKDAEKNNNVEDYVKEGLEKTIAEKKAELEKTEADLKKV
                     ANEPETPAPAPAPEKPETPAEKPALAPAPKPEKPTEQPKAEKPDDQQAEEDYARRSEE
                     EYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNA
                     NGAMAIGWLQNNGSWYYLNANGAMATGWLEYNGSWYYLNANGAMATGWLEYNGSWYYL
                     NSNGAMATGWLQYNGSWYYLNANGSMATDWVKDGDTWYYLEASGAMKTSQWFKVSDKW
                     YYVNGSGALAVNTTVDDYRVNANGEWVN"
BASE COUNT         1424 a          603 c          806 g          860 t
ORIGIN      
        1 ttattttttc tatgctgatg ttgatgttgg tgattcactt gttgggagat atttggacag
       61 tgaagcttat gcttgtcaat aatcacaaat atgtagatca tatcttgttt aggacagtaa
      121 aacaccctaa ttacttttta aatattttac ctgagttgat tggcttgacc ttgttgagtc
      181 atgcctatat gacttttgtt ttagtttttc cagtttatgc agttattttg tatcgacgaa
      241 tagctgaaga ggaaaagcta ttacatgaag ttataatccc aaatggaagc ataaagagat
      301 aaatacaaaa ttcgattcat atacagttca tattgaagtg atatagtaat agacttcatg
      361 cgaaacaaaa tatggtacaa tagttctatg aattatgaag caaggttgag aatatttttg
      421 ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg
      481 gattacgaat gaatttgatt gctggcatta tcaatcatga actaggattc tagttttgca
      541 gggagtctaa tgttaagaaa aatattggag gaaataacta tgtttgcatc aaaaagcgaa
      601 agaaaagtac attattcaat tcgtaaattt agtattggag tagctagtgt agtagttgct
      661 agcttgttct taggaggagt agttcatgca gaagaggttg gtggtaggaa tacccccacg
      721 gttacatcta gtgggcaaga tttatcgaag aagtatgctg atgaagtcga gtcgcatcta
      781 aaaaaaatat tgagtgagat ccaaacacaa ttagatagaa aacgacatac caaaactgta
      841 gcgctaatta acgagttgca agacattaag aaaacgtatt tgtataattt aaatgtttta
      901 aaagagaagt cgaaagctga gttgccgtca aaaataaaag caaagttaga cgtagctttt
      961 gagcagttta aaaaagatac attgaaacca ggagaaaagg tagcagaagc tgagaagaag
     1021 gttgaagaag ctaagaaaaa agccaaggct caaaaagaag aagatttccg taactaccca
     1081 accaatactt acaaaacgct tgaacttgaa attgctgagt ccgatgtgaa agttaaagaa
     1141 gcggagcttg aactagtaaa cgaggaagtt aaggaacctt taaacgaggg cacaattaag
     1201 caagcaaaag agaaagttga gagtgaaaaa gctgaggcta taaggttaga agaaatcaag
     1261 acagatcgta aaaaagcaga ggctacaagg ttagaaaaaa tcaagacaga tcgtaaaaaa
     1321 gcagaagaag aagaagctaa acgacaagca gatgctaaag agcaagaaaa accaaagagg
     1381 cgggcaaaac gaggagttcc tggagtgcta gcaacacctg ataaaaaaga aaatgatgcg
     1441 aagtcttcag attctagcgt aggtgaagaa actcttccaa gcccatccct taatatggca
     1501 aataaaagtc agacagaaca taggaaagct gctaaacaag tcgatgaata tatagaaaaa
     1561 atgttgagtg agattcaatt agataaaaga aaacataccc aaaatttcgc cttaaatata
     1621 aagttgagca gaattaaaac ggagtatttg tatggattaa aagagaagtc ggaagctgag
     1681 ttgccgtcaa aaataaaaga aaagttagac gcagcttttg agcagtttaa aaaagaacca
     1741 gaacttacta aaaaagtagc agaagctaaa caaaaagcag aagaagctga gaaaaaagcc
     1801 aaggctcaaa aagaagaaga tttccgtaac tacccaacca atacttacaa aacgcttgaa
     1861 cttgaaattg ctgagtccga tgtgaaagtt aaagaagcgg agcttgaact agtaaaagag
     1921 gaagctaagg aacatcgaaa cgaggaaaaa attaagcaag taaaagcgaa agttgagagt
     1981 aaaaaagctg aggctacaag gctagaaaaa atcaagacag atcgtaaaaa agcagcagaa
     2041 gctaaacgaa aagcagcaga agctgagaaa aaagctgctg aagccaaacc aaaagtggat
     2101 gcagaagaat atgctcttga agctaaaatc gctgagttgg aatatgaagt tcagagacta
     2161 gaaaaagagc tcaaagagat tgatgagtct gactcagaag attatgttaa agaaggcctc
     2221 tgtgctcctc ttcaatctaa attggatacc aaaaaagcta aactatcaaa acttgaagag
     2281 ttgagtgata agattgatga gttagacgct gaaattgcaa aacttgaaga tcaacttaaa
     2341 gatgctgaaa aaaacaataa tgtagaagac tacgttaaag aaggtttaga gaaaactatt
     2401 gctgagaaaa aagctgaatt agaaaaaact gaagcggacc ttaagaaagt agctaatgag
     2461 ccagaaactc cagccccagc cccagctcca gaaaaaccag aaactccagc tgaaaaacca
     2521 gcgctggccc cagctcctaa accagagaag ccaactgaac aaccaaaagc agaaaaacca
     2581 gatgatcaac aagctgaaga agactatgct cgtagatcag aagaagaata taatcgcttg
     2641 actcaacagc aaccgccaaa aactgaaaaa ccagcacaac catctactcc aaaaacaggc
     2701 tggaaacaag aaaacggtat gtggtacttc tacaatactg atggttcaat ggcgacagga
     2761 tggctccaaa acaacggttc atggtactat ctaaacgcta atggtgcaat ggcgatagga
     2821 tggctacaaa ataatggctc atggtactac ctcaacgcta atggtgctat ggcaacaggt
     2881 tggctagaat acaatggctc atggtactac ctcaacgcta atggtgctat ggcaacaggt
     2941 tggctagaat acaatggctc atggtactac ctcaacagca atggcgctat ggcgacagga
     3001 tggctccaat acaatggctc atggtactac ctcaacgcta acggttcaat ggcaacagat
     3061 tgggtgaaag atggagatac ctggtactat cttgaagcat caggtgctat gaaaacaagc
     3121 caatggttca aagtatcaga taaatggtac tatgtcaatg gctcaggtgc ccttgcagtc
     3181 aacacaactg tagatgacta tagagtcaat gccaatggtg aatgggtaaa ctaaacctaa
     3241 tataactagt taatactgac ttcctgtaag aactctttaa agtattccct acaaatacca
     3301 tatcctttca gtagatacga tacccttgta ggaagtttag attaaaaaat aactctgtaa
     3361 tctctagcca gatttatagg ctctttgtca actgtagtgg gttgaagact aaaatcgaga
     3421 aaggacaaaa tttgtccttt cttttttgag tacgacgggc atgtcgtgca tctggggtgt
     3481 aagtcctccg tgggcacccg ttaccggtga acccaatagc gattcccaag tctgactatc
     3541 gtgaggtagc ggggagagga agggatagcg aaatcgtggc tctacgaaca ggaaagtgat
     3601 agtaaggcgt atatagcgga taagggggct taaaactcta aagtccaaaa aggtagtcgt
     3661 aacctatatg cgtaaatcac gagagtaaac gag
//
LOCUS       DAVLZS010000094         3660 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLZS010000094 DAVLZS010000000
VERSION     DAVLZS010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.094"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..497
                     /locus_tag="VYO88_002007"
     rRNA            <1..497
                     /locus_tag="VYO88_002007"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            549..621
                     /locus_tag="VYO88_002008"
     tRNA            549..621
                     /locus_tag="VYO88_002008"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:582..584,aa:Ala,seq:tgc)
     gene            746..3647
                     /locus_tag="VYO88_002009"
     rRNA            746..3647
                     /locus_tag="VYO88_002009"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1025 a          755 c         1074 g          806 t
ORIGIN      
        1 caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag tcccgcaacg
       61 agcgcaaccc ctattgttag ttgccatcat ttagttgggc actctagcga gactgccggt
      121 aataaaccgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg acctgggcta
      181 cacacgtgct acaatggctg gtacaacgag tcgcaagccg gtgacggcaa gctaatctct
      241 taaagccagt ctcagttcgg attgtaggct gcaactcgcc tacatgaagt cggaatcgct
      301 agtaatcgcg gatcagcacg ccgcggtgaa tacgttcccg ggccttgtac acaccgcccg
      361 tcacaccacg agagtttgta acacccgaag tcggtgaggt aaccgtaagg agccagccgc
      421 ctaaggtggg atagatgatt ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg
      481 gctggatcac ctcctttcta aggataagga actgcgcatt ggtcttgttt agtcttgaga
      541 ggtcttgtgg ggccttagct cagctgggag agcgcctgct ttgcacgcag gaggtcagcg
      601 gttcgatccc gctaggctcc attggtgaga gatcaccaag taatgcacat tgaaaattga
      661 atatctatat caaatagtaa caagaaaata aaccgaaaac gctgtagtat taataagagt
      721 ttatgactga aaggtcagaa aataaggtta agttaataag ggcgcacggt ggatgccttg
      781 gcactaggag ccgacgaagg acgtgacaaa cgacgatatg ccttgggtag ctgtaagtaa
      841 gcgatgatcc agggatttcc gaatggggga acccaacagg tagtacctgt tacccacatc
      901 tgttaaggat gtgaggagga agacgcagtg aactgaaaca tctaagtagc tgcaggaaga
      961 gaaagcaaaa gcgattgcct tagtagcggc gagcgaaacg gcagaagggc aaaccgaaga
     1021 gtttactctt cggggttgta ggactgcaat gtggactcaa agattataga agaatgattt
     1081 gggaagatca gccaaagaga gtaatagcct cgtatttaaa atagtctttg tacctagcag
     1141 tatcctgagt acggcgggac acgtgaaatc ccgtcggaat ctgggaggac catctcccaa
     1201 ccctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag gtgaaaagca
     1261 ccccgggagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt tcgagcccgt
     1321 taatgggtga gagcgtgcct tttgtagaat gaaccggcga gttacgttat gatgcgaggt
     1381 taagttgaag agacggagcc gtagggaaac cgagtctgaa tagggcgcct tagtatcatg
     1441 acgtagaccc gaaaccatgt gacctaccca tgagcaggtt gaaggtgcgg taagacgcac
     1501 tggaggaccg aaccagggca cgttgaaaag tgcttggatg acttgtgggt agcggagaaa
     1561 ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc tagcgtcgac
     1621 attagagatt cttggaggta gagcactgtt tgggtgaggg gtccatcccg gattaccaat
     1681 ctcagataaa ctccgaatgc caatgaatta tggtcggcag tcagactgcg agtgctaaga
     1741 tccgtagtcg aaagggaaac agcccagacc accagctaag gtcccaaaat aattgttaag
     1801 tggaaaagga tgtggggttg cacagacaac taggatgtta gcttagaagc agctattcat
     1861 tcaaagagtg cgtaatagct cactagtcga gtgaccctgc gccgaaaatg taccggggct
     1921 aaaacaattt accgaagctg tggatacctt tataggtatg gtaggagagc gttctatgtg
     1981 tgatgaaggt ataccgtgag gagtgctgga acgcatagaa gtgagaatgc cggtatgagt
     2041 agcgaaagac aggtgagaat cctgtccacc gtaagactaa ggtttccagg ggaaggctcg
     2101 tccgccctgg gttagtcggg acctaaggag agaccgaaag gtgtatccga tggacaacag
     2161 gttgatattc ctgtactaga gtatgtagtg atggagggac gcagtaggct aactaaagca
     2221 gacgattgga agagtctgtc taagcagtga ggtgtgaatt gagtcaaatg cttaattcta
     2281 taacattgag ctgtgatggg gagcgaagtt tagtagcgaa gttagtgacg tcacactgcc
     2341 aagaaaagct tctagcgttt aaacatactc tacccgtacc gcaaaccgac acaggtagtc
     2401 gaggcgagta gcctcaggtg agcgagagaa ctctcgttaa ggaactcggc aaaatgaccc
     2461 cgtaacttcg ggagaagggg tgctgactta aagtcagccg cagtgaatag gcccaagcaa
     2521 ctgtttatca aaaacacagc tctctgctaa atcgtaagat gatgtatagg gggtgacgcc
     2581 tgcccggtgc tggaaggtta agaggagtgc ttagcgtaag cgaaggtatg aattgaagcc
     2641 ccagtaaacg gcggccgtaa ctataacggt cctaaggtag cgaaattcct tgtcgggtaa
     2701 gttccgaccc gcacgaaagg cgtaatgatt tgggcactgt ctcaacgaga gactcggtga
     2761 aattttagta cctgtgaaga tgcaggttac ccgcgacagg acggaaagac cccatggagc
     2821 tttactgcag tttgatattg agtgtctgta ccacatgtac aggataggta ggagtctaag
     2881 agatcgggac gccagtttcg aaggagacgc tgttgggata ctacccttgt gttatggcca
     2941 ctctaaccca gataggtgat ccctatcgga gacagtgtct gacgggcagt ttgactgggg
     3001 cggtcgcctc ctaaaaggta acggaggcgc ccaaaggttc cctcagaatg gttggaaatc
     3061 attcgcagag tgtaaaggta taagggagct tgactgcgag agctacaact cgagcaggga
     3121 cgaaagtcgg gcttagtgat ccggtggttc cgtatggaag ggccatcgct caacggataa
     3181 aagctaccct ggggataaca ggcttatctc ccccaagagt tcacatcgac ggggaggttt
     3241 ggcacctcga tgtcggctcg tcgcatcctg gggctgtagt cggtcccaag ggttgggctg
     3301 ttcgcccatt aaagcggcac gcgagctggg ttcagaacgt cgtgagacag ttcggtccct
     3361 atccgtcgcg ggcgtaggaa atttgagagg atctgctcct agtacgagag gaccagagtg
     3421 gacttaccgc tggtgtacca gttgtcttgc caaaggcatc gctgggtagc tatgtaggga
     3481 agggataaac gctgaaagca tctaagtgtg aaacccacct caagatgaga tttcccatga
     3541 ttatatatca gtaagagccc tgagagatga tcaggtagat aggttagaag tggaagtgtg
     3601 gcgacacatg tagcggacta atactaatag ctcgaggact tatccaaagt aactgagaat
//
LOCUS       DAVLZS010000095         3644 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLZS010000095 DAVLZS010000000
VERSION     DAVLZS010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3644
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.095"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(50..199)
                     /gene="blpO"
                     /locus_tag="VYO88_002010"
     CDS             complement(50..199)
                     /gene="blpO"
                     /locus_tag="VYO88_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV1720038.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCTAGVAYGAIDG
                     CATTV"
     gene            complement(443..646)
                     /gene="blpN"
                     /locus_tag="VYO88_002011"
     CDS             complement(443..646)
                     /gene="blpN"
                     /locus_tag="VYO88_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV1720039.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(662..916)
                     /gene="blpM"
                     /locus_tag="VYO88_002012"
     CDS             complement(662..916)
                     /gene="blpM"
                     /locus_tag="VYO88_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV1720040.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            complement(1066..1870)
                     /locus_tag="VYO88_002013"
                     /pseudo
     CDS             complement(1066..1870)
                     /locus_tag="VYO88_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(2073..2477)
                     /locus_tag="VYO88_002014"
     CDS             complement(2073..2477)
                     /locus_tag="VYO88_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1720041.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            complement(2474..2638)
                     /locus_tag="VYO88_002015"
     CDS             complement(2474..2638)
                     /locus_tag="VYO88_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720042.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(2935..3054)
                     /locus_tag="VYO88_002016"
     CDS             complement(2935..3054)
                     /locus_tag="VYO88_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1720043.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(3057..3236)
                     /locus_tag="VYO88_002017"
     CDS             complement(3057..3236)
                     /locus_tag="VYO88_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family peptide pheromone/bacteriocin"
                     /protein_id="HEV1720044.1"
                     /translation="MCWSTHWCNWGDFAKAGVGGAAARGLQLGIKTGTWQGAATGAAG
                     GAILGGVAYAAICWW"
     gene            complement(3152..3418)
                     /locus_tag="VYO88_002018"
     CDS             complement(3152..3418)
                     /locus_tag="VYO88_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEV1720045.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGEILPKQVLEEQQQEVFN"
BASE COUNT         1182 a          771 c          518 g         1173 t
ORIGIN      
        1 gcagcaccag ttacacctat tcctatagca aatggtccca atagaaatgt caaaccgttg
       61 ttgcacaccc atcaattgcg ccatatgcaa cccctgctgt acaactaatt tttcttcccc
      121 aatcaatatc tccaccttca acgcaagcaa gcatttcatt atccataact gcaaattgtg
      181 acatcatttt tgtatccata tagtatatca cttttcagtt acggaacaag tttaatataa
      241 aaattatcaa aaaaacatag gcaataaaga gaaaaattaa tttatcatag attagaaata
      301 atatgacaaa acaattcaat gatgttaatt caatagtctt ttgtttttta tcggagatac
      361 ttatggatag ataaataaga taggtttgaa aagcgaagag aataataaag aatatagcct
      421 tcataaaatt tagctttcat ttttatgatg tagcggtata ggctaaatat ccacaaacca
      481 ctgctcctcc aattcctcct attgcagcgc cccatggtcc tagaagtctc ccatatttca
      541 ctccacccgc tgcacaacct aaagcagcaa ctacagctgc tcctccggaa ttacctccat
      601 aaacctcact cagcattgtt tcatttatat tacaataagt attcatacaa gtctcctttt
      661 attaaaatcc acccgttgcc cctgttactc ctgcccaaag atccacacca aatttagctc
      721 ctatgtatcc acatgctccc ataaatggtg ctccaacacc actcgcagca caaatagctg
      781 tccctagccc ccagccacca aaagcagcac caccaccttc taagacatta gtttgccaat
      841 tattcttgcc tccttcaata ctagataaca tagttatatc catttcatga aattgttcca
      901 taatttttgt atccatgaca aatactcttt tttattttta atatttgtct tgttacaaac
      961 ttgacaagtt tagtatatca tcgtttttta aaatttttca tccagatctt gaatagtcat
     1021 cgaaacgtct tgaattgcaa aaattacatt agacttcctg caaaactaga atcctagttc
     1081 atgattgata ataccagcaa tcaaattcat tcgtaattcg aagcgtttac gatgatttcg
     1141 ataggttgtt gaaaacattt taaacgtttt tactttggca aagatgttct caaccttgct
     1201 tctctccttg gatagcgcat ggttataagc cttatcttca gctattagcg gcttgagttt
     1261 actggattta cgtggagttt gtgcttgagg atatatcttc atgggccctt gataaccact
     1321 gtcagacaag attttaccag cttgtccgat atttctgcga ctcattttga acaacttcat
     1381 atcatgacaa tagttcacag cgatatccaa agaaacaatt ctcccttgac ttgtgacaat
     1441 cgcttgagcc ttcatagcgt ggcatttctt tttaccagaa tcattcgcta attctttttt
     1501 taggacgatt tatttttacc tctgttgcat ccacaatcac cgtgtcctca aaactgagag
     1561 gagttcttga aatcgtaaaa ccactttgaa caagagttac ttcaacccat tagctccgac
     1621 ggagtaagtt gctttcgtgg ataccaaaat cagccgcaat ttgttcataa gttcgatatt
     1681 ctcgcacata gtgaagagtg gccataagaa ggtcttctag gcttaattta ggttttcgtc
     1741 caccttttgc gtgtttaagt tgataagctg tttttaatac agctaacatc tcttcaaaag
     1801 tggtacgctg aacaccaaca agacgcttaa atcgtgcatc ggttagttgt ttacttgctt
     1861 catcattcat agaactatag taaaatgaaa taagaacagg ataaatcgat caggacagtc
     1921 aaatcgattt ctaacaatgt tttagaagta gaggcgtact attctagttt caatctacta
     1981 tactatacca tattttgttt cgcagggaat ctattataaa agggtaagta ttgcaaaaac
     2041 acttaccctt ttcttttata cttcattaag ctctactttt tataatactt caagccccac
     2101 atgagcagaa gcatgatgat taagcagaga acagcgccaa tataagcgat tatttgttgg
     2161 taggattctc ctgctgtgat acctctatac aaacaaataa tagacataaa acctgtcaag
     2221 ccgatgaaca taagttgatt ggttctagga ctaaccaaat catcatcttc aaactctctt
     2281 atcctcattt ccctagtgag ataaacagta accaaaatag aagccaagtt aataactact
     2341 aaaagaaatt ggaaaactac ggaaaaattt aaaaactgac gagatagaaa tagataagta
     2401 gaaacaagca agggcaactg acctaagaac aatctcgcaa ggaagatgtt ccgtttttta
     2461 gcaagaaaag ttttcatttc ttttctcctt tctttttatt gatagcaaaa tagatcataa
     2521 ctgcaatcac ataggctatg gtataaaata gctgatacca agcactctcc ctaagcggat
     2581 atagaaagat ggacatgatt agatacagaa cgaaaataat cagtattttt ttcttcataa
     2641 gatttcctcc taaatgtgcg atttatctta gttgagcaag aacatttaca ctgctagtat
     2701 agcacttatt ttgaccttgg atcactcaaa tcataaatgg tcatcaaaac ctcttgaatt
     2761 gtaaaaatta aaaaagcaag catgaaaaac atactttcct ctttatattg tattgatacc
     2821 aacttgtttg tagacttttc atcctgctat cacatatcat tttgacaggc gaaacaaaat
     2881 taaagaaact cccctgtaaa ttaagctagc aaatacaggg gagaaattta ttttttagag
     2941 agtactatcc gtatcctttt tggaagattt tgaaaatatt tttctaatta agtcatccat
     3001 ataaggacca aatataccaa ctactaaacc aataataaaa cttttaaaat ccataattac
     3061 caccaacata ttgctgcata ggctacacct ccaagtatag ctccacccgc agcaccagtt
     3121 gctgcacctt gccatgttcc tgttttaatg cctagttgaa gacctcttgc tgctgctcct
     3181 ccaacacctg ctttggcaaa atctccccaa ttgcaccaat gtgtgctcca acaaatgcac
     3241 cagcaagtcc agctactcct aaagtggcca aacctgctcc agttccacca gttataattc
     3301 ccgtagtgac tcctgtaatc agtgcatttt gacaatcagt ggagctatac cccccttcaa
     3361 ctttcgcaag catttcagta tccataacct ctaactgtga caacattttt gtattcatga
     3421 tgaatacctc ctttttattt tcaatttgtt accaaagtct taaattcaat aaacaaatag
     3481 attttttata gtatcttttt gattttctta aaaaagtata tacgtctact atcttcttaa
     3541 aggtagcagt acctattttt tagtctaaga tttcaataat cttgagtatc taaaatatct
     3601 taatttcgtt attctccttg caataaaaag ttttactata ctat
//
LOCUS       DAVLZS010000096         3221 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLZS010000096 DAVLZS010000000
VERSION     DAVLZS010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.096"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..410
                     /locus_tag="VYO88_002019"
     CDS             <1..410
                     /locus_tag="VYO88_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720046.1"
                     /translation="NRPILEFKKKFPLTYRYLEEALSEEYKKNYGIFFGRTQGFLGYH
                     SSKVIIPKVADLKNSPFKLINEGFVQSGLSITFFENYSNRVLTRIVDYLNSPTVLNYL
                     SNISKNYAAGYQNISSTDLKYIKIPRRLLEDDV"
     gene            407..2632
                     /locus_tag="VYO88_002020"
     CDS             407..2632
                     /locus_tag="VYO88_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1720047.1"
                     /translation="MKETLKYIVEDKVLAEVLGRNNFSTKESAVLELVKNAYDAGAEK
                     LTISFRKSKSTGKLFIEIVDDGIGMSSEDIKNAWMHVGKSTRDYIDSKTGRVFAGSKG
                     IGRFALARLGEVIELRSHKEGNSKIKWTTDWEKSKLESIESTNDEQGTIIRIYDLRDK
                     WSSRNIDPLKDYLSKVYYDNQMEITLDYRTDEIAITNKTENIWANPKIGENFVDSIEI
                     NYDSSTQKLNIKLTLDEFNSSVEEIVGYSTVGKEFALDVVSELKKDIIKLLKEDDEDK
                     EVTEEEIKNVLLDLGDFSGRLYFSLVSITEKDAEKFEYKYKTLTNRYTHGVILYRNAF
                     SIDSFEGRRDWLKLSQRAVSSPAAATHPNGSWRVRPNQVSGHISIDKRKNKYIEDISN
                     RQGVVENIYYHIFLEIIHIALKEFESYRQGIIRTINEYQTALLEKAIYNEQREITAEE
                     IVRDTIKNPDRITELTKTDFEKIQEKLNVQRKVIDNLGEDRKRIEEDYRYEVQLLNVL
                     STLQLKVSSLSHEVKNNRNSIAANPTKIQEVLKRKYDWDALKLDKPSSRNLPLLIETL
                     SNDLEKVLDLADTIIDETKKDNFVVKEFKLDEITGLIINKWKQQYNWVNFIIKVEPDE
                     KITISYDLLMVILDNLILNSIQNNENVSGLSITVELNYTYGILNLVYFDNGKGLDAKY
                     KDKPEKILNVHETTREDGHGLGMWIVSNTIYKLGGEIKINPNYQGFFLSASILINESE
                     D"
     gene            2635..>3221
                     /locus_tag="VYO88_002021"
     CDS             2635..>3221
                     /locus_tag="VYO88_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720048.1"
                     /translation="MTSDIKLTYIDDKLDPLLVDYLYTISEKEHIFEYDEYKFDSSKD
                     SYQSLLENTSIASSDIIIVDSKLFENEFADSKSKFTGQELKIIYAIANPFIKIIVITQ
                     NNDLSKYGVIKKFATSRKCSGREQEEANRYYNDVLRKEIETLIKNVKEVRNVGQLLSE
                     NILSYEDSLIVEKANNLISKIPSYKDLTDEKINEL"
BASE COUNT         1281 a          370 c          585 g          985 t
ORIGIN      
        1 aaaatagacc aatattagaa tttaaaaaga agtttccgct aacttataga tatttagaag
       61 aggcactatc agaagagtat aaaaaaaatt acggaatttt ttttggaaga actcaaggat
      121 ttttaggata tcatagcagt aaagtaatta ttccaaaagt ggctgatttg aaaaactcac
      181 catttaaact cattaacgag ggatttgttc agtcaggtct atcaattaca ttttttgaaa
      241 attatagtaa tcgagtgttg actagaatag tagactattt gaattcacca actgttttga
      301 actacttatc taatatttct aaaaactatg cagcgggtta tcaaaatatt agctctaccg
      361 atttaaaata tattaaaatc ccaagaagat tattggagga tgatgtatga aggagacatt
      421 aaaatatatt gttgaagata aagtcttggc tgaagtgtta ggaagaaata acttttccac
      481 aaaggaatca gctgtcttag agttagtaaa aaatgcctat gatgcaggtg ctgaaaaatt
      541 aactatttca tttagaaaat ccaaaagtac cggaaaactt tttattgaaa ttgtcgatga
      601 tggaattggt atgagtagtg aggacatcaa aaatgcttgg atgcatgttg gtaagtctac
      661 tagagattac atagattcca aaactggaag agtctttgct ggttctaaag gaatagggag
      721 atttgcactt gctagattag gtgaagtaat tgaactacgt tctcataaag aaggaaattc
      781 taagattaaa tggactacag actgggaaaa atctaaactg gaaagtatag aatcaactaa
      841 tgatgaacag gggacaataa ttagaattta tgatctcaga gataaatggt catctagaaa
      901 tattgatcca ttaaaggatt atttgagtaa agtttattac gataatcaaa tggaaattac
      961 ccttgattat agaacagatg aaattgctat tacaaataaa acagagaaca tatgggcaaa
     1021 tcctaaaatt ggcgagaatt ttgttgattc tattgaaatt aattatgatt ctagtactca
     1081 aaaattaaat attaaactaa cattagatga attcaatagt tctgttgaag agatagtggg
     1141 ctactctaca gtgggaaagg aatttgcttt agatgttgtt tcagagttaa aaaaagatat
     1201 tataaaatta ttgaaagaag atgacgaaga taaggaagtt acagaagagg aaatcaagaa
     1261 tgtattgctt gatctaggtg atttttctgg aagattatat ttcagtctag tatctattac
     1321 agaaaaggac gctgaaaaat tcgagtataa atataaaaca ttaacaaata gatatactca
     1381 tggtgtaatt ttatatcgaa atgcctttag tatcgattca tttgaaggga gacgagattg
     1441 gttgaagcta tcacaaagag ctgtatcttc acctgcagca gctactcatc caaatggatc
     1501 gtggagagtg agacctaatc aagtttcagg gcatatctca attgataaaa ggaagaacaa
     1561 gtatatagaa gatatatcta ataggcaagg tgttgtagag aatatttact atcatatctt
     1621 tttagaaatt atacatatcg ctttaaaaga gtttgagtcg tatcgtcaag gaattattag
     1681 aacaattaac gaataccaga ctgcactatt agaaaaagca atttataatg aacaaagaga
     1741 gattactgcc gaggagattg ttcgagatac tattaaaaat ccagatagaa ttactgagtt
     1801 aaccaagact gattttgaga aaatccaaga aaagttgaat gttcaaagaa aagttataga
     1861 taatctcgga gaagatcgaa aaagaattga agaggattat cgttatgagg ttcaattatt
     1921 gaatgtttta tcgactttac aattaaaagt aagctcatta agtcacgagg ttaaaaataa
     1981 cagaaattct atcgcggcaa atccaactaa aatacaagaa gttttgaaaa gaaagtatga
     2041 ctgggatgca ctgaaacttg ataaacctag ttctagaaac ttacctctgc tcattgagac
     2101 actctcgaat gatttagaaa aagttttaga tttagctgat acaatcattg atgaaactaa
     2161 aaaagataac tttgttgtca aagagtttaa attagatgag ataactggtt tgattatcaa
     2221 taagtggaaa caacaatata attgggtgaa ctttataatc aaagtagaac cagacgaaaa
     2281 aatcacaatt tcttatgatt tactaatggt aatacttgat aatttaattt taaatagtat
     2341 tcaaaataat gaaaatgtta gcggactatc aataactgta gaattaaatt atacctatgg
     2401 aattcttaac ttagtatatt ttgacaatgg taaaggatta gatgctaagt ataaagacaa
     2461 accggagaaa attttaaatg tacatgagac tacaagagaa gatgggcatg ggcttggaat
     2521 gtggattgtg agtaatacta tatataaatt aggaggcgaa attaaaataa atcctaatta
     2581 tcaaggattt ttcctttccg cttcaatatt aattaatgaa agtgaggact aacaatgact
     2641 agtgatataa aactaacata tatcgacgat aagcttgatc ctcttctagt tgactattta
     2701 tacacaataa gtgagaaaga gcatattttt gaatatgatg agtataaatt tgatagtagt
     2761 aaggatagct atcaaagttt actagaaaat actagtatag cttcttcaga tatcattatt
     2821 gtcgattcaa agctttttga aaatgaattc gcagattcaa aatctaaatt tactgggcag
     2881 gaactgaaga ttatatatgc tatagcgaat ccttttatta aaatcattgt tattacacaa
     2941 aataatgatc tttcaaagta tggagtaatt aaaaaatttg cgacatctag gaagtgttca
     3001 ggaagagaac aagaggaagc gaatagatat tataatgatg ttcttaggaa agaaatagaa
     3061 acattaataa aaaatgtaaa agaagtaaga aacgttggtc aattattatc tgaaaatatt
     3121 ttatcatatg aagatagcct aattgttgag aaggcaaata atttaatcag taaaattcct
     3181 agttataaag atttaacaga cgaaaagatt aacgaattaa t
//
LOCUS       DAVLZS010000097         3161 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLZS010000097 DAVLZS010000000
VERSION     DAVLZS010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3161
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.097"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(284..1012)
                     /locus_tag="VYO88_002022"
                     /pseudo
     CDS             complement(284..1012)
                     /locus_tag="VYO88_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(1258..1569)
                     /locus_tag="VYO88_002023"
     CDS             complement(1258..1569)
                     /locus_tag="VYO88_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720049.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(1584..2870)
                     /locus_tag="VYO88_002024"
     CDS             complement(1584..2870)
                     /locus_tag="VYO88_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1720050.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATLRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
BASE COUNT          952 a          681 c          545 g          983 t
ORIGIN      
        1 taatgcaata tataaatgtc attttgtaaa attttattaa taaaaaaact ctctacaaca
       61 aaataataga gagttttctg cttattaatt tttttcaaaa tatctaagac atcgcttctt
      121 tgtttaattt gataggcttt gatacctaag ctccgacttt atcacttaaa aaataaaaaa
      181 ggacagctaa tctcttgcgc atcaagggat ttcgccattc tttaatctcg tttaagtgtt
      241 gtatatggag ctttgcacaa ttttttaaaa ctaaacaact acattaagca cgaactgtga
      301 cgctggttcc atcttcctta taaagattga taagcccctc tttaagagct cgaaccatgt
      361 ctcctgattg aacaggttgt gggactttaa tagtcaatag ttccattgga tttggagcgc
      421 ggtcgatttt attgcctttg gcatcatgca aatcttcaat ataggtttca aaatgacgga
      481 aacctggacc ataaaactca acttggtccc cttcgttaat gacatttcgt tgacgaatag
      541 ttgctgtttg tgccgcatca tcataagaaa ccacttcagc gacaaacttg tactcaggaa
      601 ttttacgacg agcaccaaac aactgctcat tttcagatgg tgtaccatag taaaatcctg
      661 tagccagttc acgttgggca accttccaca tctcgtccac caagtcttgt ttgatagctt
      721 caaacttttc aggactttca agataggcat ccacagccgc cttgtagcag ttggttactg
      781 ttaatacata gtgaatagac tccatacgtc cttcgatttt tagactgtcc acaccatttt
      841 caatcatatc tggaatgtgg tcaatcatag acatgtcaac ggctgacatt gaaaattctt
      901 ctggaatctc accctgcaaa ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt
      961 acttccaacg gcatgactga gaacatccac cacggttggc atcacgcata ctctagacgg
     1021 attgttttga caattctaat cttttagact ttgcataata actgttaaac agttgaaaat
     1081 taacccagtt ttaacaagta gtcaaaatac cagataaagg aaaaaagtct ttaaaatctt
     1141 aaaaacgcat agtatcaggt attgaacaat cttgatatta tgcgttttat tgtgggaaga
     1201 tttacttcat tttctcttgg aattgagttt tctcctactt caaaactaga tgatttgcta
     1261 tttaaaatag cgttccttat gattttggca acctggatta aagcgagaaa aacaaaaggg
     1321 gcaacttaaa ctttctttat attgcttata tgttagtagt tttagacaaa caccacataa
     1381 aataggctta tcctgtatca aagataaggg atacggctca aaagggtgat tttctaatga
     1441 atcatgacac cgataacaag cataatactt tttacaatca tagcattgta aagcaataat
     1501 atccagcttg ctatggtaat gaatgcatct tgtttgctta tccactaaga aaccctgtgc
     1561 ctctatcatt tccttttcct ttcttaagct cgaactgtga cgctggttcc atcttcctta
     1621 taaaaattga tgagtccttc ttttaatgca cgaaccatgt ctcctgattg aacgggttgt
     1681 gggactttaa tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgcctttg
     1741 gcatcatgca aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca
     1801 acttggtccc cttcgttaat gacgtttcgt tgacgaaggg ttgctgtttg taccgcatca
     1861 tcataagaaa ccacttcagc gacaaacttg tactcaggaa ttttacggcg agcaccaaac
     1921 aactgctcat tttcagatgg tataccgtag tagaaacctg ttgccaattc acgttgggca
     1981 accttccaca tctcgtccac caagtcttgt ttgatagctt caaacttttc aggactttca
     2041 agataggcat ccacagccgc cttgtagcag ttggttactg ttgatacgta gtgaatagac
     2101 ttcatacgtc cttcgatttt tagactgtcc acaccatttt caatcatatc tggaatgtgg
     2161 tcaatcatag acatgtcaac ggctgacatt gaaaattctt ctggaatctc accctgcaaa
     2221 ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt atttccaacg gcatgactga
     2281 gaacatccac cacggttggc atcacgcata ctcatgtggt ttgaaagagt acaacgtcca
     2341 gagtatgaaa tacacatagc tccatggaca aaggcttcaa tttcaacatc tgtacgtttg
     2401 cggatctcag ctaattcttc cattgaaacc tcacgcgcta aaacgacacg agtcaagcct
     2461 agctctttcc agaactcaag ggtttcatag ttagtggcac tggcttgggt agaaaggtgg
     2521 atttcaaggc ctggtgcttc agtcgctgca atcataatca aggctgggtc agatacgata
     2581 actgctgcaa tcccgatatc acgcagttta cggaaccact caccagcacc agcttcattt
     2641 ccttcgtgca taaccatatt agccgctaca tagaccttgg caccatactt ggccgcaaac
     2701 tgcacgcctt cttccatctg ttcgaaagta aagtttcccg cacggctacg aagaccatag
     2761 gcctgaccac cgataaagac agcatctgct ccatactgaa cagctacctt tagcttctct
     2821 aaagtccctg caggtgataa aacctcagga cgttttaatg tttttgtcat gatttctcct
     2881 atttgcaata taaaagtttg acatttttcc ttctcatttt atagtaaata aaggataaaa
     2941 tcaagcctag acggattgtt ttgacaattc taatctttta gactttgcat aataactgtt
     3001 aaacagtcga aaattatccc agttttaaca agtagtcaaa aagtctagaa aagtaaaaac
     3061 cagtatccca agatactgac tcgtaaaaat acataaatta gtccttagat gactactccc
     3121 actctgtttc tcctataatg gaaaaggatt gatacagtct a
//
LOCUS       DAVLZS010000098         3137 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLZS010000098 DAVLZS010000000
VERSION     DAVLZS010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.098"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..170
                     /locus_tag="VYO88_002025"
     CDS             <1..170
                     /locus_tag="VYO88_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1720051.1"
                     /translation="TVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSGVTLIT
                     GKNGTGKSTLL"
     gene            complement(536..1846)
                     /locus_tag="VYO88_002026"
     CDS             complement(536..1846)
                     /locus_tag="VYO88_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1720052.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2083..2955
                     /locus_tag="VYO88_002027"
     CDS             2083..2955
                     /locus_tag="VYO88_002027"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1720053.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT          964 a          525 c          710 g          938 t
ORIGIN      
        1 gaactgtttc ttttgctatt agttcaaaag gagaaaaaat gaaagtagaa aatatttcgt
       61 atagggtgga tcatcgtata ttgtttgata atatttcttt tgatacttcg agttcaggcg
      121 tgacattaat tactggtaaa aatggtacag gaaagtcaac tttactatag tagattgaaa
      181 ctagaatagt acacatctac ttctaaaata ttgttagaaa tcgatttgac tatcctgatc
      241 tatttgtcct gttcttattt catttcacta catctcaaat tgagtatgac gaagtgcgct
      301 cccatgtcct gggaacgcac tttcttcata tttttcatat tcttgaatcc atcgataaag
      361 actattggga tgaattttta aagttgaact aatcattttt acaggatgag gtttacagca
      421 gagagtttga aggctttatc aaaggttttt cttggcataa tgacttttcc tcgtttccac
      481 ttaattttgt gtctacttta ttataccaag tccaccctta agttagataa taaatctaac
      541 ttaaggaagc tagaaggatg agaatccagg tggtcaagag tcccaaactt aagctgatgg
      601 ggacacccag aataatttgc tttttgaagg caaggccacg ttcctctata ttgggaagtg
      661 agagttgaat gagagaacca gctgatgaaa agggtgagat attagtagat agagcgccaa
      721 taacggtggc tgttgtgagt aagtgaatat caatctgagg attttgagca ctgatgatag
      781 caatgatggg aaagagggct ggagctacaa cggatagggt ggaactaaag agtgacatca
      841 ctccggctat cacacaaaag aacagaggta accagaaatg aggaatggat gttgtcatga
      901 ggtgccctat cagtgtgact aaacctgact tgaccgctag agacattagt aagctcatgc
      961 cgcagagcat gataattgta gcccagggaa ctttagccaa aatggcttct tgcttcccta
     1021 atttgagcct taaggcgagg cagaccatga gtattgagac aaagccaata tcaaatgttt
     1081 tttgataagt agctatccag gcgatgtttg ggaaaatgag atgcaacaag ggaaaaagcc
     1141 aaaccaaaac catgctgctg atcatgagca aggtggtttg tctttgaacc ttgctgagga
     1201 gtggtggttg gtcaatagtc aaggatgagt ttgttcttcc cttactatag tgactgtaac
     1261 aggataataa aagcaagacg atgagtgggt agataatgct gacgataaag atatgattgc
     1321 caagtgaaaa agcttgctct tcccatccca tttgcttaaa caggccttga aagacaatgc
     1381 ctgagctact ggttatcaaa ttagcccctc ctgaagctcc ccaattgacg gcttgagctc
     1441 caatcaaagg gtgtttgtcc gctttttgac agagggtaat cgctagagga cagcaaacgg
     1501 ccatagtagt gaaaaatcca gcacctaaag cagacaaaag ggttgccatc aggtataaaa
     1561 tcatgtagag ggcgttaggg taggtgcgtg tgcggtagag aatgtgttga gccaaaacat
     1621 caagagtacc gttagttatt gcaaagttat aaaagagaga gacgctaaaa atggtaaaaa
     1681 agagtgaggt tggccaaaaa tgaagaagtt ctttggggct taatcccatg agagtggttg
     1741 cgatgaggta agaaaaagca atagccagca ggccaatatt gattttggtg cggtaaccaa
     1801 ttccaatggc tagagcaatg gcgctaatca ttattaaatg aatcattgaa ttgtcctttc
     1861 agttagaata tggaaatagg ttggcaattt tggcgctcaa aagaccacct gtttcctatt
     1921 ggtacttgac tattatacac aaaaaaaata caattgtctt gacaattgta ttgacacttg
     1981 ttagaattaa aaatgaggta ttcaggcttg tgatttccta tggaagttaa tagtgattgc
     2041 ctctagtgct tacaagtgat attaaaaata gaggacttag tgatgtcaat catttcaact
     2101 gatttaaccc cttttcaaat agatgataca ttgaaagcag ccttgcgaga agatgttcat
     2161 tccgaagatt acagtaccaa tgccattttt gatcatcatg gccaagccaa ggtgtcgctt
     2221 tttgccaagg aagctggtgt tttagcggga ctaaccgttt ttcaaagggt ttttacccta
     2281 tttgatgccg aggtgacctt ccagaatcct catcaattta aggatgggga tcgtttgact
     2341 agtggcgatt tggttttaga aatcataggc tcggtgagaa gtctcttaac atgtgaacgc
     2401 gttgccttga attttttaca acatttatca gggattgctt cgatgacagc tgcttatgta
     2461 gaagccttag gcgatgattg cattaaggta tttgatactc gaaaaactac tcctaattta
     2521 cgtctttttg agaaatatgc cgtgagagtt ggcggtggct ataatcatcg ctttaattta
     2581 tcagatgcta tcatgctaaa agacaatcac attgcggcag taggtagtgt tcaaaaggca
     2641 attgctcaag cgcgtgccta tgcccctttt gtgaaaatgg tcgaggtgga agtggaaagc
     2701 cttgctgctg ccgaagaagc tgcggcggcg ggtgctgata ttatcatgtt ggataatatg
     2761 tcattggaac agattgaaca ggccattacc ctaattgcag gacgttctcg gattgaatgt
     2821 tctggaaata ttgatatgac cactattagc cgttttcgtg gtttagcgat tgattacgtc
     2881 tccagtggta gtttaaccca tagtgctaag agtcttgatt tttccatgaa gggtttaacc
     2941 taccttgatg tctaagttgt aaaataaact aactttttaa aggatgtctt tcctctagaa
     3001 cgagttttat gtcagatagt ttaaacgcct cttcaaatat agtaaaatga accaaaaata
     3061 gtacacaatg tggtataatc ttcttatggc atattcaata gattttcgta aaaaagttct
     3121 ctcttattgt gagcgaa
//
LOCUS       DAVLZS010000099         3071 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLZS010000099 DAVLZS010000000
VERSION     DAVLZS010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.099"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..327)
                     /locus_tag="VYO88_002028"
     CDS             complement(<1..327)
                     /locus_tag="VYO88_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720054.1"
                     /translation="MSEVDFNEAVTYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCIGDFPHDFF
                     DIYLDHV"
     gene            complement(385..1098)
                     /locus_tag="VYO88_002029"
     CDS             complement(385..1098)
                     /locus_tag="VYO88_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1720055.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1557..1943)
                     /locus_tag="VYO88_002030"
     CDS             complement(1557..1943)
                     /locus_tag="VYO88_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV1720056.1"
                     /translation="MESIGIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEG
                     GGIGTSFDQVDRVVSENPADTLLVFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAY
                     NAAALLQAGAELSVIQIQLAELEINK"
     gene            complement(2365..>3071)
                     /locus_tag="VYO88_002031"
     CDS             complement(2365..>3071)
                     /locus_tag="VYO88_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1720057.1"
                     /translation="STDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVK
                     NGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFG
                     NASDHVQRNKNGQADTNQTEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEE
                     SPEESEEPQVETEKVKEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNT
                     IMAEAEKLLALLKESK"
BASE COUNT          928 a          608 c          500 g         1035 t
ORIGIN      
        1 tacatgatct aggtatatat caaaaaagtc atgaggaaaa tctcctatac agccattacg
       61 attcatattg aggctatatt ttcgattagt aagataattc ggaaatatat ttcctattac
      121 tctaagatta tctacttgtg aatcccttct cccaatataa tccccttctt tgactaatga
      181 tggagatttc caagtaaaaa ttaaatcgcc agagaaattt ttcttatcaa aaaacttaaa
      241 aagagattga taaatactat ttgctaattg acaagtgtca gatgtaaatt cataagtaac
      301 agcttcatta aaatcaactt cagacatttc aatgtactct tcaatagtaa tattagcttt
      361 tttgtagtca ttagctcgtc tcctttaaaa tgtgatcttt tcaagaatat ttttatctaa
      421 acaatccagc aagtcttggt aagaatagac ttcgtaagtc ggctgggctt gtgtgtgatt
      481 ttcgaggtga tgaggattat accagatagt gtcaatcccc gcattattgc caccttgaat
      541 gtcggcggtt agagaatctc caatcatcag cgtcttttct ttactaaatc cagcaatttg
      601 ctggccaatc ttttcataaa aaagagcatc cggcttttga gtttgcaact gttctgagat
      661 aaagacttga ttgaaataag gtgctagacc agattgagcc aaacgtcctg tctgaatggc
      721 agtaatgcca tttgtcgcag catacaagtt ataatcacgc tcaatgaggc tgtccaagag
      781 atcatgagcg cccgatagtg tttgtccctg ctgggcgagg taaaattggt aacgctgggc
      841 aagaaaacta ccgtcttttt cctgtccaaa atgagcaaat aaacgagaaa agcgcgtgtt
      901 aaccagctct tgtttactga ttttcttcag ctccaagtct ttccagagag ccttgttcat
      961 aggaacgtaa taatctttat aagcctgaat atccgcaact ccttcttctt ttagaagttg
     1021 ggtcaaagcc acatcctcag cagcatcaaa atcaagaaga gtgtggtcga ggtcgaagag
     1081 tagaaatttg tagaacaatt tgaggttttc ctttctgaaa attcattaag aacattatat
     1141 cataaagcac ctcatacaat taactaattt aatcacttaa aaaaaattcg aacactttct
     1201 atacaactga cagctcaaat ctttcagaat agaacaatac taactatcga gcaccccatc
     1261 ttcataaata tatgtgtaat tctagaccta gaattcctat aaactaaatg ctttcatact
     1321 cttccaagta attgatttcc ttaaatttta atttttgaag gattctaaag ctagaatagc
     1381 cccatcacaa tcagttttga ttgattcaca atttagaaac actatagttt cactcctgtt
     1441 aaaataaaaa ggaattgcat aaagcaatcc ctttctgatt ttgaaatcat ttacttaaca
     1501 ttttatagtt gagataatca atagcttacc tataaaaaga gttatagtaa aattccttat
     1561 ttattgattt caagctccgc taactgtatt tgaataactg acagttctgc accagcctga
     1621 agaagagcag ctgcattata ggcaccttct acaattggaa ccctgttgat gatgatactt
     1681 ttatcactga aatcagtcac catttttaag ttcattttag cagaacctag gtcaaaaaat
     1741 acaagtaaag tatctgctgg attttcggaa acaaccctat ctacttgatc aaaactcgtt
     1801 ccaattcctc cgccctcggt tcctcctaca taagtaatcg gaacatcttt agctacttta
     1861 ctaatcagtt caacaacacc ttctgcaatg tgtttggaat gtgaaacgat aacaagacca
     1921 ataccaatac caatactttc catcaaacca ccccagtttc taaaatagca gtaaagaata
     1981 atcctgatga gaatgatcca ggatcaatat gtccaagaaa ccacatgctc ctaagacaag
     2041 agctaacaga ctggccatca ataatagtat tgttcttttt ttcatcatta ctccttaact
     2101 agtgtttaac tgattaatta gccagtaaat agtttatctt tatttacact atctgttaag
     2161 atacagtaaa atgaaataag aacaggacag tcaaatcgat ttctaacaat gttttagaag
     2221 tagaggtata ctattctagt ttcaatctac tatattttgc acattttcat gaaaaaaatg
     2281 agaactagaa ctcacattct gctctcattt ttcgttttcc cgttctccta tcctgttttt
     2341 aggagttaga aaatgctgct acctttactt actctccttt aataaagcca atagtttttc
     2401 agcttctgcc ataatagtat tgttgtcctg ggtgccaaat agtaaattat tttttaatcc
     2461 tgtgagagtc tctttggcat tggacttgat aattggatcc tggatttttc caagtaaatc
     2521 ttcagcctct ctcagttttt ctttaacctt ttcagtctcg acctgaggtt cttctgattc
     2581 ctctggtgat tcttctggtg attcttcttc tggttcctct gttggttttg gagactccgg
     2641 tttctcgctt tgcggtttct cttctcgagg ggtttcttcc tcaggttttt ctgtctgagg
     2701 tttttccgtt tgattggtat cagcttgacc atttttgttt ctttgaacat ggtcgctagc
     2761 gttaccaaaa ccattatctg aatgcggacg ttcgtttgga tgttcgacat agtacttgac
     2821 agtcgccaaa agatcctcaa gactataccc cttaggtgcc tcataaaggc cttcgtcaaa
     2881 ccactcaaat ttgatgttat ggtaatggtc ataatgaggt atgattaaac taccgttttt
     2941 gacttctaca gtatattgaa gattgtaagg catacgatca agtggcacct tcttagctgc
     3001 tttcacgcgg ttgtagatag cttctgctcc ttttgcctca gtatttcctg aatcctgatg
     3061 gtctgtcgaa g
//
LOCUS       DAVLZS010000100         3008 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLZS010000100 DAVLZS010000000
VERSION     DAVLZS010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.100"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            97..552
                     /locus_tag="VYO88_002032"
     CDS             97..552
                     /locus_tag="VYO88_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004834933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1720058.1"
                     /translation="MYFDKKLINTFVNVDNQEELFRFMSDSLYDSGCVKDFFYDGIVS
                     RESEYPTGIQIGNVGFAIPHTDSKHVLESQICFVSLKKPILFADMTDINNKFPVNLVF
                     MLAMKEPGDQIKSLQKLMEIFANEEVISFLLETDNKDEILNILKENGID"
     gene            578..1918
                     /locus_tag="VYO88_002033"
     CDS             578..1918
                     /locus_tag="VYO88_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1720059.1"
                     /translation="MSVLINSFQWFIGLGSNVFLPIIIFILGIIFGLKPGKALMSGIT
                     VGIGSIGLGLVLNLLSGSMGSAIQDLGNHYGSSLNILDIGVGVGGPLAFSTSLGLLMI
                     PISLVVNIFFVFLGLTRTLNVDIWNFWFPIFMGMITQSITGNFVFGILGGTVAVMIQW
                     LLADINQKKNSEFFGYPGIAISHMMVNSGAIIARPLNWIFDRIPGLNKIDLDTESLTK
                     RFGILGDTVFIGLVIGALVGIFAKYDVSKIGNLAVSTAAVMKIMPKMVAMFMEGLGPI
                     AEAASDFANNKLGGRQVNIGMDAALVVGHSAVMSTSILLVPISLALALVLPGNQVLPF
                     GDLAFFAFAIAMMVPFFKGNVIRTVLGSAIYVVACLYLSTWLAPVMTDVFNLASFDVG
                     TAGLVTMLLAALWPVALYVLALKYLGIFGVVAIGILVILIMYYINKIKKISYFQ"
     gene            1950..2234
                     /locus_tag="VYO88_002034"
     CDS             1950..2234
                     /locus_tag="VYO88_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004834925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1720060.1"
                     /translation="MKKILVICGAGHATSTIAVSKIKKWLEDNNLDSDAKIYQSKIAD
                     ELNKFDDYDVVVSTTVVPDSVKEKVINGVALLTGVGIDKVFEQIRKELEK"
     gene            2234..2755
                     /locus_tag="VYO88_002035"
     CDS             2234..2755
                     /locus_tag="VYO88_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004834929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HEV1720061.1"
                     /translation="MIIHDFIKLETVAGRPSFHDITDDIKEIVEQNSITDGIIVISSS
                     HTTCSLFFDEDMHDRNYFGDDFLHVDIAKMMDKIAPPMRSEGDYHSPGEKHVEFGLNL
                     CDSEFPPEKWTMLNTDAHLKSSLFGSNSMTLIIKDKKILLGKLGKVFFVDWDHLRERD
                     RNISILLLGEKNG"
     gene            2739..>3008
                     /locus_tag="VYO88_002036"
     CDS             2739..>3008
                     /locus_tag="VYO88_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1720062.1"
                     /translation="MKKMVNILPSILNSDFWNIKETLNILNNSETKEIHIDIMDGNFV
                     EDMAFGPKFVRTIREHTDLKLDLHLMIINPERKIEKFIEAGADSIT"
BASE COUNT         1069 a          341 c          577 g         1021 t
ORIGIN      
        1 ataaaaagat aaattcaaaa gaaaaagttg ataagttggt agggtgtaaa aagcctgagg
       61 aattaataga agaaattaga agtatatgag gtggatatgt atttcgataa gaaattaata
      121 aatacgtttg taaatgttga taatcaggag gagctattta gatttatgtc agatagctta
      181 tatgatagtg gttgtgtaaa agattttttt tatgatggga tagtaagtag agaatctgaa
      241 tatccaacag gaatacaaat aggaaatgtt ggttttgcaa taccacatac ggattcaaaa
      301 cacgttttgg agtctcagat ttgttttgta tctttaaaaa aaccaatact ttttgcagat
      361 atgacagata ttaataataa atttccagta aatttggtat ttatgctagc tatgaaagag
      421 ccaggtgatc aaataaaatc tttacaaaaa ttgatggaaa tatttgctaa tgaagaagta
      481 ataagttttc ttttagaaac agataataaa gatgaaattc ttaatatttt aaaagaaaat
      541 ggtattgact aaaatataaa tttattagga ggataaaatg tcagttttaa ttaattcgtt
      601 tcaatggttc ataggccttg gatcaaatgt ttttttacca attataatat ttattttagg
      661 gattatcttt ggtctaaaac caggaaaggc cttaatgtca ggaattacag taggaattgg
      721 ttcaatcggt cttggactag tattgaattt attatcaggt agtatgggaa gtgcaattca
      781 agatctggga aatcattatg gaagctctct taatatatta gatataggtg ttggagttgg
      841 aggaccttta gctttctcta catctttagg cttgctgatg atacctattt cacttgtagt
      901 taatatattt ttcgtatttt taggcttaac tagaacttta aatgtagata tttggaattt
      961 ttggtttcct atatttatgg gaatgattac ccaatctatt accggtaact ttgtgtttgg
     1021 tatactaggt ggaaccgttg cggtaatgat tcagtggtta cttgcagata taaatcagaa
     1081 aaaaaatagt gagttttttg gctaccctgg tatagccata agccacatga tggttaattc
     1141 aggtgcaata attgcccgtc ctttaaattg gatttttgat agaatacctg gtctaaataa
     1201 aattgatctt gatactgaat ctttaactaa aaggtttgga atattggggg atacagtttt
     1261 tataggatta gttataggtg cactagtagg tatttttgct aaatatgatg tatctaagat
     1321 cggaaatctt gctgtatcta cagcagcggt aatgaaaata atgcctaaaa tggttgctat
     1381 gtttatggaa ggtctgggac caatagcaga agctgcctca gattttgcta ataataaatt
     1441 aggtggtaga caagttaata taggaatgga tgctgcacta gtagtaggac actctgcagt
     1501 tatgtctaca tcaatattac tagttccaat ttctttggct cttgcattag tattaccggg
     1561 caatcaagtt ttaccttttg gagatttagc atttttcgca tttgctatag ctatgatggt
     1621 tcctttcttt aaaggaaatg ttattagaac tgtactagga agtgctatat atgttgtagc
     1681 ttgtctatat ttatcaacat ggttagctcc agtaatgaca gatgtattta atttagctag
     1741 tttcgacgtt ggaacagcag gattggttac aatgctactc gctgctttat ggccagttgc
     1801 tttatatgta ttagctttaa aatatttagg catatttgga gtcgtagcaa taggaatatt
     1861 agtaatacta ataatgtatt acatcaacaa gattaagaaa atttcatatt ttcaatagaa
     1921 tataaatata aaatataaag gagataaaaa tgaaaaaaat attagtaatt tgtggagccg
     1981 gtcatgcaac atcaaccata gctgtttcta aaataaaaaa gtggttagaa gacaataatt
     2041 tggattctga tgcaaaaatt tatcaatcaa aaatagctga tgaactaaat aaatttgatg
     2101 attatgatgt cgttgtaagt acaacagttg taccagattc agtaaaggaa aaagtaatta
     2161 atggagttgc tttattaact ggtgttggta tagataaggt atttgaacaa atacgcaaag
     2221 aattggaaaa ataatgatta tacatgattt tattaagtta gaaacagttg caggaagacc
     2281 atccttccat gatataacag atgatattaa agaaatagta gagcaaaatt ctataacaga
     2341 tggaataatt gttatatcaa gctctcatac aacatgttca ttattttttg atgaggatat
     2401 gcatgataga aattattttg gagatgactt tctacatgtt gatatagcta aaatgatgga
     2461 taaaatcgcc ccaccgatga ggtctgaggg cgattaccat agtcctggag aaaaacatgt
     2521 agagtttgga ttaaatctat gtgattcgga atttccacca gaaaaatgga ccatgttaaa
     2581 tacggatgcc catctaaaat cttcactatt tggcagcaat tcgatgactc ttataataaa
     2641 agataaaaaa atcttattag gaaaacttgg taaagtattt tttgttgact gggatcattt
     2701 gagagaaaga gatagaaata ttagcatttt attgttgggt gaaaaaaatg gttaatattt
     2761 taccttcgat tctaaatagt gatttttgga atatcaaaga aacattaaat attctaaata
     2821 atagcgagac aaaagaaatc catatagata taatggatgg aaattttgtt gaagatatgg
     2881 catttgggcc aaagtttgta agaactataa gagaacatac agatctgaaa ttagacttac
     2941 atcttatgat tattaatcct gaaagaaaaa ttgaaaaatt tatagaagct ggggctgaca
     3001 gtataact
//
LOCUS       DAVLZS010000101         2929 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLZS010000101 DAVLZS010000000
VERSION     DAVLZS010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.101"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(140..673)
                     /locus_tag="VYO88_002037"
     CDS             complement(140..673)
                     /locus_tag="VYO88_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1720063.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(762..1538)
                     /gene="recX"
                     /locus_tag="VYO88_002038"
     CDS             complement(762..1538)
                     /gene="recX"
                     /locus_tag="VYO88_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1720064.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDINENIVSQVIANLKEEKW
                     INDSQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1576..>2929
                     /gene="rlmD"
                     /locus_tag="VYO88_002039"
     CDS             1576..>2929
                     /gene="rlmD"
                     /locus_tag="VYO88_002039"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1720065.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          922 a          537 c          531 g          939 t
ORIGIN      
        1 tacgaattct gcataaatct ctttctagta atgtgttgta actctgctat aatggattta
       61 ttcctttttg tgtttacaca atttatttta tactaccaaa aaaacaaggt caggattttg
      121 ttcctgacct ttgacaactt taccgattct ttagttctac atagcgcttg taccaaatgt
      181 ttacataggc ttctgagaaa ggaccacgtc cattgttaat ccaatcaaca agaattttga
      241 catgttcttt taaaatatag tccaagtcat cagaataatt cattttgcgt ttgtgacgct
      301 cgtactcttc aacgtccaag agacgttttt ccccatctgt aaaaatttta acatccaaat
      361 cgtaatcaat atacttcagt gcttcttcat ccagatagta ggggctagcc atattgcaat
      421 agtaagaagt tccattatca cgaatcatgg caatgatatt aaaccaatat ttcttgtgaa
      481 agtaaacaat agccggttct cgagtgaccc aacgacgacc atcactttcg gtaacaagtg
      541 tatgatcgtt gacaccaata atggcgtttt ctgttgtttt tagtaccatg gtgtcccgcc
      601 aagttcggtg gagactccca tcatgcttat aactttgaat tgtaataaag tcgccttctt
      661 ttggaagctt cataactaac caactttcta caatttataa gtttatcatt tactattgta
      721 ccataaaatt acccaaaatc tgtgaatttc acttggaaat attaaagata ttctctaaga
      781 gcgcttgcta tatccgaaaa atcgtaaccc tttcgtgcta aaacttgagt taaacgctgc
      841 ttcagttcgt atccttcata ctttcgggca tacttagtat attgcttatc aagttccttg
      901 aagatgagtt cctgagtcgt ttcttcatca acttgactat ccaattcgtc aaaggcaatt
      961 ttagcatcaa aataagagaa gcccttgtta gtcaagttct ggataatctt atcttgcagg
     1021 gcacgagctg gaagttttcc ctcatatttt ttcaatagtt tattggctac acgttgagca
     1081 acttccgaaa aatcaaaatc attcaagatt tcttctatag tagattttga aattcctttt
     1141 tgtgctaatt tctgagtcag tacataaggt cccttgtctc ctgaaagttg attggcattg
     1201 atgatagcat aagcgtactg gctatcatta atccacttct cttctttaag attagcaatg
     1261 acttgagaaa cgatgttttc attaatatca tattttttca gatattctct gacctctttt
     1321 tcagtacgtg ctttaaagga taagtggtag agggccagat tcttaccata agaaaattga
     1381 gcaaagtctt gaatctcttt caattcctct tcgcttatca ccttatctct cgataacata
     1441 aaacgaacaa ttgtgtcttc ggtgatatag catttgtcgc cattatcaag ctccatcaga
     1501 tagagtcttt ttttcttttc aagttttgtg attttcatag ctctattata actcaaaatg
     1561 tgataagata ggggtatgaa tctgaaagtg aaacaaaaaa taccattaaa aatcaagcgc
     1621 atgggaatta acggtgaggg aatcggcttt taccaaaaaa cattagtctt tgtaccagga
     1681 gctctcaaag gcgaagatat ctattgtcag attacttcta ttagacgcaa ctttgttgaa
     1741 gcaaaattac tgaaggtcaa caagaagtct aaatttcgaa ttgtgccatc ttgtactatt
     1801 tataatgaat gcggaggctg ccaaatcatg cacctgcatt atgataagca gctggagttc
     1861 aagacggact tacttcatca agcgctgaaa aaatttgctc ctgcaggata tgaaaattat
     1921 gaaattcgtc caactattgg aatgcaggaa ccaaaatatt acagagctaa gttacaattt
     1981 cagactcgaa aatttaaaaa tcaggtcaag gcgggcttat atgcacaaaa ctctcactat
     2041 ttagtagagt tgaaagactg cctggtacaa gataaggaaa cccaagtgat tgctaatcgc
     2101 ttagcagaat tacttactta tcaccagatt ccaatcacgg atgagagaaa agttctaggt
     2161 gtccgtacta ttatggtccg acgcgcgaga aagaccggac aggttcagat tattattgtt
     2221 acaaaccgcc agcttaattt aactcaattg gtaaaagagt tggttaaaga tttcccagaa
     2281 gttgtgacag tagctgttaa tacaaataca gctaaaacca gtgagatata tggtgaaaag
     2341 acagagatta tctgggggca agagagtatt caagaaggtg tactcaatta tgaattttca
     2401 ctatcccctc gagcttttta tcaactaaat cctgagcaaa cagaagtcct ctatagcgaa
     2461 gcagtaaaag cgctggatgt tgataaagaa gaccatttga ttgacgctta ttgtggagtt
     2521 ggaacgattg gatttgcctt tgcaaagaaa gtaaaaacac tcagaggtat ggatattatt
     2581 ccagaagcta ttgaagatgc caagcgaaat gctaaaagaa tgggatttga caatactcat
     2641 tatgaagctg gaacggcaga agagattatt cctcgttggt acaaggaagg ctaccgagca
     2701 gatgctttga ttgttgaccc accacgtaca ggtctggatg ataagttatt agatactatt
     2761 cttacttatg taccagaaaa aatggtttat atttcttgta atgtttcgac cttggctcgt
     2821 gatttggtac gcttagtaga agtctatgat cttcattata tccagtcggt cgatatgttc
     2881 ccacatacag ctcgaactga agctgttgta aaattaataa aaaaagttt
//
LOCUS       DAVLZS010000102         2768 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLZS010000102 DAVLZS010000000
VERSION     DAVLZS010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.102"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            209..1429
                     /locus_tag="VYO88_002040"
     CDS             209..1429
                     /locus_tag="VYO88_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HEV1720066.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFNNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEGASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            1442..2623
                     /locus_tag="VYO88_002041"
     CDS             1442..2623
                     /locus_tag="VYO88_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1720067.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREKGTLNLIKPGRIARQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYFMDDEGVMFNQTWLHQGGSWYAFKSSGAMISA
                     DWLYDNGSWYYLKDSGSMVTGWLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSM
                     ATGWVKDSGSWYYLKNSGSMATGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAW
                     K"
BASE COUNT          926 a          380 c          596 g          866 t
ORIGIN      
        1 tgccattttc gaaacgagaa atagttgatt cactaatttc attacatgat aaatctttaa
       61 ggcgaaaatt ttttgaaata cgaatatcct ttaaaactgc tccgaaattt tccataatgt
      121 tcctcttcca tttctgcaaa aaataaaacg cttgtttttt atttatgata tgattataca
      181 aaaataaaat agaaaggaca ataatatcat gaaaaaaatt ttattgtcaa cagttgcttt
      241 attaagctta gtagcatctc tgctagcaaa taatccagtt tctgctcaag aatcatcctc
      301 tcaagcaact tatagtaagt caagtggaag ttggataaaa tctggtaacc gttggtggta
      361 taagcattct gatggttctt atactacaaa tggatgggaa aaaataaatg gtacctggta
      421 ctattttgat agtgaaggtt ggatgaagac aggttggatt aaagaatatg ggaaatggta
      481 ttacctagat gatagtggtg ctatgaaaac tggatggtgt ttggtttctg gtagctggta
      541 ttatttaaat agtagcggtg taatgcaaac gggactacag actatcaatg gaaaacaata
      601 ttatttagct gccggcggtg ctatgcagac aggttggcac aatatcggag atgataccta
      661 tttctttgct aatagtgggg aaaatcaaaa tatcaatcgt cgtgctttag ttcttggtga
      721 aacatcaacg agagcagtac ctattgcaga tgttaatgct atggaaaagg tttttaataa
      781 ccaaaacttt agtgaagttg ttcgtttccc agatagaaca aaatccgaga taattgcaaa
      841 aatgcaagag ctttttgaat cttctagcga aggcgatgtg aactatcttt actttacttg
      901 tcatggagga agagatggaa gaatctatat tggtagtgat ggcctagcat tttctggttg
      961 ggaattggcg tccgttttga aacaatacaa aggtaagttt gttgttatgc tggattgttg
     1021 tcatgctgga acaattattt ctaaagataa tacaggtgaa ggcaatgaag gagcctctac
     1081 ggaatatttt gatttagatg aatttgtatc aggattttct aatatggatg gtaacgaaaa
     1141 atcaggtgag atgattgact ctaaattttt agtattatgc tcatcaagag gtgcagaata
     1201 ctctagtggt ggatcattaa gtttagcgac taaatattgg tctttaggtt caggatggaa
     1261 tcctctacag aattcacaag catatttagc agcagaccaa aataataatc gcagaatcac
     1321 attaaatgaa ttgtatacat actctcgtga acaagttttg aaacaaaatt ctaaccagca
     1381 tattgaagtt tatcctgaca acagtcaatt tgtgttattt aagaaataag ggggcaataa
     1441 aatgaaagta tcaaaaaaaa ttacactatt tagtttgtct tttgcaggtt ttgttttatt
     1501 gactttacct caagcaggaa aggcttttga acttaaagaa gactgggcat ttaaaggtgg
     1561 cattcgatac gagaatggga aagtcagcaa aattaataat ggatatgaag taaatattaa
     1621 agtgttagat ttacctagta ctagcgcaat cgaatggaca gttagattga atggagaaaa
     1681 gcaaaatact aacttcttag cggaggaaag aactgtatct aaaactgaag ataagggacg
     1741 tttcttgcac ttttatatcc cctatggata tcgtggggat attgtagtag aggctaagag
     1801 tggaaacgaa gtgaagactt ggtctactaa ggtagttgac gatgtttatt cagattctgc
     1861 taagagtggc tactttattc tcgatgggga acaaatctta gaaagttcat gggattccgt
     1921 aaatgagtct tatattgcaa cgcttccaac tgtaacatca ggaaaaactg ttgttgcttg
     1981 gcgtgaaaaa ggaactctta atttaattaa accaggaaga attgctcggc aatataatag
     2041 cagtggatca tatgtagaac tttctccaat ctttgaaact gctagttggc taaaatcaaa
     2101 ccaaaactgg tactatcaaa aacaaggtca attagttcaa aattcttgga tcaaggatca
     2161 gggaagctgg tactttatgg atgatgaagg ggttatgttt aatcaaacat ggctacacca
     2221 aggtggaagc tggtatgcct ttaagtcatc aggagccatg atttcagctg attggttgta
     2281 tgataatggt tcttggtatt acctaaagga ctcaggttct atggtaacag gatggcttaa
     2341 aaatggaggc tcttggtatt acctaaacaa gtcaggttca atggctacag gttggattaa
     2401 agatagtgga acttggtatt atctaaagaa ttcaggctct atggcgacag gctgggtgaa
     2461 agatagtggc tcttggtatt atctaaagaa ctcaggttca atggcaacag gttgggtcaa
     2521 agataatggt aagtggtact atctcgcatc atctggtaat atgcttcgca atacacgcac
     2581 accagatggc tattatgtag atggcagtgg cgcttggaaa taaattttta aaagagaaaa
     2641 tctactgaga aggtagattt tctttttagt taatgaatat agaataaagt agatcaggac
     2701 tggtctattt tattttgtaa ctattaatga atagtcttaa tgatgaagtt actttctgaa
     2761 gatattta
//
LOCUS       DAVLZS010000103         2756 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLZS010000103 DAVLZS010000000
VERSION     DAVLZS010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.103"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(111..1040)
                     /gene="psaA"
                     /locus_tag="VYO88_002042"
     CDS             complement(111..1040)
                     /gene="psaA"
                     /locus_tag="VYO88_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1720068.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(1072..1920)
                     /locus_tag="VYO88_002043"
     CDS             complement(1072..1920)
                     /locus_tag="VYO88_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1720069.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(1917..2639)
                     /locus_tag="VYO88_002044"
     CDS             complement(1917..2639)
                     /locus_tag="VYO88_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1720070.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKTKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT          811 a          515 c          571 g          859 t
ORIGIN      
        1 tcttttttct tccattgtat ctgaaacagt cagaattttc caatgatttg accggaaatg
       61 tgtgcataga aaaaacgcca gctcacatga gaatgacgtt tttcagaggc ttattttgcc
      121 aatccttcag caatcttgtc aaggttgtat ttcatcatgc tgtagtagct gtcgccttct
      181 ttaccttgtt ctgcgataga gtcagtaaag atttgtgcgt agattgggat gtttgtgtct
      241 tgagaaacag ttttcattgg acggtcatcc acacttgatt ctacaaagag tgatggaact
      301 tttgtttggc gaagtttttc aaccaaggtc ttgatttgtt caggagttcc ttcttcttca
      361 gtattgattt cccagatgta ggcacttggg acaccatagg ctttagagaa gtatttgaat
      421 gctccttcgc tggttacaat gagtttcttt tcagcaggga tcttattaaa tttatcctta
      481 ctttctttat caagtttgtc taacttatca gtatattctt tgagattttt ttcatagaat
      541 tctttattgt tagggtcttt ggcgctcaat tgtttggcga tatttttagc aaaaataata
      601 ccgttttcaa ggttaagcca agcgtgtggg tcttcttttc ctttttcatt ttgaccttca
      661 aggtagataa catcaacgcc gtcgctgact gcgaagtagt ctttgttttc agttttcttg
      721 gcattttcta ccaattttgt aaaccaagca ttgccacctg tttcaaggtt gataccgtta
      781 tagaaaatca aatcagcctc agaagttttc ttaacgtctt caggaagtgg ttcgtattcg
      841 tgtgggtctt gcccaatcgg aacgatacta tgaaggtcaa ttttgtcacc agcaatattt
      901 ttagtaatat cagcgatgat tgagtttgta gcaacaactt ttagtttttg accagaagtt
      961 gtatcttttt ttccgctagc acatgctaca agaatgattg cagaaagaaa gagaacgagt
     1021 aatgtaccta attttttcat tagatcctcc aatttattag ggctttgccc cttattttaa
     1081 caaatgttta tttttcagtt tcaaatatcg ttgtttggga gcgataaaga agctaatgag
     1141 aaagaaacta gcagctgtaa gcacgatact agaacctgcc gcaacattaa aactatagcc
     1201 aataaagagt cccaaaactg aagcagtagc tccgaaggtt gaggaaagga aaatcatgct
     1261 tttcagacta ttagcataca gataagcagt tgcagctggg gtaatcagca tggctacaat
     1321 caggatagtt ccgacacttt gcatggctgt cacagacacg agagtcagga gtaccatgag
     1381 aaggtagtga tagaaattga caggcattcc catggcttta gccaagagtt catcaaagga
     1441 agttatcaag agttgcttga agaaaatcca gattaacaag aggatggctg cccccacacc
     1501 catagtaata aacatatccg tatcttggac ggccagaata ttaccaaaaa ggatatggaa
     1561 aaggtcagtt gaacttttag cgacaccaat caagatgata ccgagggcta agaaagaaga
     1621 aaaggtaatg ccgatggcgg tatcgctttt gataatcgag tttcctttga tgtaggtaat
     1681 gatgatggca gctagcaatc caaagacaat ggctccgata aagaagtcaa ggcccaagat
     1741 gaaggagagt gctacacctg gtaagacagc atgtgaaatg gcatctccca tgagtgacat
     1801 cccgcgtaga ataatgaaac atcccacagc tccagctaca atcccgacga caatagctgt
     1861 tatcaaggca ttttgtagga aatggaattt ttgcaatcca tcgataaatt ctgcaatcat
     1921 aggtcacctc cattgaaaaa gagttgatta ccgtaagctt cttttagatt ggtttcggta
     1981 aaagtttctt ttgttggacc aaaggcaatc acttctcgat tgacaagtaa gacttgatcg
     2041 aagtagtggg gaatcttgct gaggtcgtgg tgaacgatga gaaccgtctt cccagctttt
     2101 ttcaaatctc tcagcgtatt catgatgatt tcctcactga cagaatcaat cccagcaaag
     2161 ggttcatcca agaggatata gtcggcttcc tgcaccaaac atctggcaat caagacccgc
     2221 tggaattgac ctccagacag ttgactaatt tgacgttcag cgtagtcagc taggccgacg
     2281 atttcaaggg cctcttgcac tttcttccaa tgtttagtct ttaaacttcg aaagagagga
     2341 atagagggaa atagtcctaa cgagacgcat tccttgacct tgatgggaaa gttgtagtcg
     2401 atattgattt tttgttcgac ataggcaatt cggtgtaagg attttttaac ttccttgtca
     2461 tcgagaaatg cctgaccttg atgtgggata attcccagca taccttttaa tagtgttgat
     2521 ttcccagcgc cgtttggacc aatgatgccg gtaattgttg gtccatggag cactagtgaa
     2581 atatccttaa gtgccaacgt ttctttgtag gagacactga ggttttcgat acgtatcata
     2641 aacttgtatt cctcctgtct cttaatatac attaaaaaaa aaattaagtc aagttaattt
     2701 ttgaaaaaat taaaataata actgaaaaat agattctaaa gataactttc aggata
//
LOCUS       DAVLZS010000104         2633 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLZS010000104 DAVLZS010000000
VERSION     DAVLZS010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.104"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..949
                     /locus_tag="VYO88_002045"
     CDS             <1..949
                     /locus_tag="VYO88_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV1720071.1"
                     /translation="YYIIALPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTV
                     PIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSI
                     STHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGV
                     CLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQ
                     ILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEPNLNVSIDNVIF
                     EKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            1344..2207
                     /locus_tag="VYO88_002046"
     CDS             1344..2207
                     /locus_tag="VYO88_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1720072.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQGQMAETYRRLNAIVIKNALHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKSGFLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGNNQKEIENFIQSLQVLENPQLTSLFE
                     LRLQQYKALID"
     gene            2499..2603
                     /locus_tag="VYO88_002047"
     CDS             2499..2603
                     /locus_tag="VYO88_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011225312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1720073.1"
                     /translation="MENTEFSLELDVTEVATEQDYVSSGVTSTGCCKN"
BASE COUNT          914 a          388 c          495 g          836 t
ORIGIN      
        1 ttattatatt attgcgcttc cgacagatta tgatgagaaa attggtagtt ttaatacata
       61 tgaaatcgaa caaacggtat cgaagattct gagggtaaaa cctaatggaa agattatttt
      121 aaagtcaaca gttccgatcg gcttttcaaa caaattaaaa aggctgtttg atacaaaaaa
      181 tatcattttt gtccctgaat ttttgagaga aggttgttct atatatgata atttatatcc
      241 aagtcgcata gttgttggag atgagacagt tgaaggaaga aaaattgcag agttgttcct
      301 ttcgattagt actcatagta ctgccaatat taaaaatgtt atgttagttt ctcctactga
      361 agcagaagca attaagcttt tttctaacac attcttagct ctccgtgttg ctttttttaa
      421 tgaactagat tcttttgctg agaggagaag tttaaatgct gaagttgtaa taaaaggtgt
      481 ttgtttagat ccaagaattg gaaattttta taataatcct tcttttggat ttggaggata
      541 ttgtcttccc aaagatacta aacaattaaa aaaagaattt atagaaataa atgccccagt
      601 gatagaagcg attgatattt caaacacaaa tagaaaacag ttcatagtta aacaaatatt
      661 ggaacgaaag ccaaagatag taggaatata taaattgggg atgaaatata attcagataa
      721 ttacaaagag tcagctattt taagtataat taatgaacta ttgattgtcg gtataaaaat
      781 tttagtatat gaaccaaatt taaacgttag tatagataac gtaatttttg aaaagaattt
      841 tgaactattt acaaaacaaa gcgatctaat tgttgcaaat agatgggata ggggccttga
      901 agcttataaa gataaagttt acacaagggg gatctggata agagattaac tattgatatt
      961 aaaaaggcaa taatttataa aatttgtaca aaaaaatgtt aaattttcac attttcatag
     1021 tatactgttt aatagaaagt aggttctttg taaccgctcc attataaaat cctttcactc
     1081 ttccggtata ctattaggaa aaacataact ggaggatatt ttgagctcac acctcatcgt
     1141 tccagtggct gttccccaag ctcgtgtact gcccaaaaaa gttagacatt ctatttagaa
     1201 cgaggattga gttctgtatt gtacaaggct cggtcctttt agagtcagct taaggctggc
     1261 ttttttaatc accaaagtgt cagaatgttt tgacaaatga acacaaataa tgatataata
     1321 tgcaaaagct aggaggtggt aggatgattg aaaaaatgga actgggggaa ttttacaagg
     1381 aattgcgttt ggcgagaaag ctcaagcagt cagatgtggc ttgtgctgga ctaacagctt
     1441 ctcagctatc caagttcgaa ctagggcagt ctatgctgtc tgcggataag ctcatactag
     1501 ccatccaagg gatcaatgtg acctttgatg agtttgggca caagctcaac aactatcaag
     1561 aatctccaca tatgcagatt ggtagaaagg ttgtggatcg ctttgctcat caagatatag
     1621 ctggcttaga gcaactgttg gaggaagtcg agcaaggaca gatggcggag acctatcgtc
     1681 gtttgaatgc tattgtgatt aaaaatgcac tccattcctt agataaaagc tatccgctag
     1741 cagaggagga tagcgagttt ttgactacct acctctatgc tattgagtct tggacctggt
     1801 ttgaactcta tcttttttgc aataccatgc ccttcttgag caatcaagat ctgatctttt
     1861 tatcaacctc tttgcttgaa aaatccaagg aatttaaaga gttggtacat aatagactgt
     1921 atatgaaaag tggctttctg aatattatat cagagctcat ggagcgcaag cttttctcct
     1981 atatcccaat ctttgaagca gagctggaga gcatgttgcg tccgtacgat gtttttgaaa
     2041 aagtattgtg gcaattttta aagaaaatga gtattttcct tcaaaccaaa ggaaacaatc
     2101 aaaaagagat tgaaaatttt atccaatctc tgcaagtatt agaaaatcca caattaacat
     2161 ccctttttga actacgctta cagcaataca aagcacttat cgattagtta gaaatgggaa
     2221 aaagataata atctcagcaa cgattgtcaa taatgttaaa acttgtttct tcatatgact
     2281 tccactcctc attagtaata actttattat accagggaaa tgatcaaatc tactaaaatc
     2341 gcaaatgtga aatttttata agaaaaaata tcaaatatgc gattttctaa aataagccaa
     2401 ttttcgtgtt atactgtact tactaaagta cttgaagcaa atcctaggtc gcagaagtgg
     2461 tttataagta aaaataattg gaggaggaat cgtttattat ggaaaataca gaattttcat
     2521 tggaacttga tgtgactgaa gttgcaactg aacaagatta tgtttctagt ggtgttacat
     2581 ctacaggttg ttgtaaaaac taatttaata attgatttta taaagcaggt aca
//
LOCUS       DAVLZS010000105         2619 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLZS010000105 DAVLZS010000000
VERSION     DAVLZS010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2619
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.105"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            15..1238
                     /locus_tag="VYO88_002048"
     CDS             15..1238
                     /locus_tag="VYO88_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1720074.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNIIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            2053..2223
                     /locus_tag="VYO88_002049"
     CDS             2053..2223
                     /locus_tag="VYO88_002049"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1720075.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
BASE COUNT          961 a          494 c          370 g          794 t
ORIGIN      
        1 aaaggaggaa acaaatgatt acaaaacaat cagccttttt acaaaataga gccactatac
       61 tggagtttct atatcgaaat ccagcaacat cccgtacaga tattgttaat gaaacaggac
      121 ttactccagc aacaacgact aacatcataa aagagctaag cgaacagtcc ctcatatacg
      181 aaactggtga tgaatttagc gagttttccg gatctggaag acgtagaaaa actatttcta
      241 tcacagataa tattccgtat gttgttggag gtattgaaat aaacgtccta ggtatctttc
      301 tcagtctatg tgacttacaa gggaaaactc ttttcgagac agaaattttg aatgaagatt
      361 atcctatttc agaaatcaat tccaccatta ccaatatgat aaaaacagct atagagtacg
      421 tccctttgga aacaaaatta cttggatttg gcttatcaat acctggacat tataacaaag
      481 actccggaag tatcattaca aacaacccca tatgggaatc ttttaattta ttaaatataa
      541 ttaaaagatt caattttcct tttattgtaa aaaataatat cgattgtatg gctataggac
      601 aatacctttt taatccacac aatacccccg ataactttat tttcctacac gctggattag
      661 gtatttacac ttcctttttc acaaaagaaa aaataggagc ctctaaaaat ccttatatcg
      721 gagaaattgg acacaccatt gtcgaattga atgggcaata ttgtgaatgc ggaaaaaaag
      781 gttgtttaca aacatatatt tcggatgctt ggttaatcaa acacgcccaa ttattattta
      841 aaaattccca actaactgta ctaaaaagcc ttgtaaagac tgaaaaagac attcatttag
      901 acaccctttt aacggcttat aatttaggcg actccgcttt acgtcaacaa attgataaag
      961 gagtcaattt attagccact tctattgcaa atctcctcct catcaatcct gctgataaaa
     1021 tctatatcaa cagtcaattg cttaattatc aacctttcac tcatgaagtc agggataaaa
     1081 tccaagacca gctccacttc gttcccttta ctcgtaatat agaaattgaa attttacctt
     1141 acaacaaaca tcgtggaagt ataggagctt gtgcattagc tatcgtcgct tttttcatag
     1201 aacatagcaa tgtattacaa gatattattt caccttaata tattagaaat ctatagacct
     1261 gtttaaatca actataacct gtagtagata tctcgtattt agacaatatg aaaacaagac
     1321 gacttccata taggaaaccg ccttctcgct atgttgagtg atttatatta aaataacttt
     1381 tcttctagct gcattttatt attataaaaa cattcatcat aacccccaga acttaaataa
     1441 caatttttat tcaagataca tactcctaga ataaacttta tatgaaatcc ccatttttgt
     1501 ttttacaatt ctccgtatac tcaatgaaaa tcaaagagca aactaggaag ctagctgcag
     1561 gctgctcaaa acactgtttt gaggttgtag atagaactga cgaagtcagt aacatctata
     1621 cggtaaggcg acgctgacgt ggtttgaaga gattttcgaa aagtattagt taaatcttgt
     1681 ttaatatctc tacaccatac tattttacat atattattta gcgccacata gtactgaact
     1741 ctctccaaaa acggttatgc ctctttgaat agggcgttat cacaagaaaa gcatctccac
     1801 gtttcaactt catatggctc aaaaacaatc aattgatgct aaaacctgta cctagatgtt
     1861 tcggttcata aaaccatgaa actgtaaaag tggatgaaat tgatagcgat agtcaaatca
     1921 agaggcatca taactctaaa aagtcacaat atataagttc atcctcggaa aaatatcatt
     1981 ctaattgttg aaatgcctac atgaaaagaa acgtcaaatg ctcatgaaac aacgaataca
     2041 ggtatcaaaa ctatgacaaa acaagtccct aaatttacta aagacactgc tcaactttac
     2101 acctgtaaat ggttgttgta taataaagtt acaaagatgt acgaccacac tgttgtaaat
     2161 catagtgttc gcgaatatat tactgatagc atttctacaa atacaattga agagactgga
     2221 tagactttaa acgaaatatg tcagtgtttt ggcattccta gccttcatat catttaaaga
     2281 attctataga caaaattttt cccaatacag acactcgtaa caactgcttc atttttctac
     2341 caacatattt aggaacagga taagatacaa gaggattaat ccatagatca gttctatacc
     2401 aatctaagac aaataagcta aaaaaacgat tgataataag caaatagatt ccaaattttc
     2461 tctatctgct cattttaata aacaatacta gtgtaactat ccttccagtc agaagcttgt
     2521 caaatcacac cgaaaattct tctaaaattt atctcgttag gcaatcaagc aaaaactcga
     2581 cgatagtaca aacattatca tacagaattg acttcctaa
//
LOCUS       DAVLZS010000106         2550 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLZS010000106 DAVLZS010000000
VERSION     DAVLZS010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.106"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            17..574
                     /locus_tag="VYO88_002050"
     CDS             17..574
                     /locus_tag="VYO88_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1720076.1"
                     /translation="MPESEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            631..1428
                     /gene="psrA"
                     /locus_tag="VYO88_002051"
     CDS             631..1428
                     /gene="psrA"
                     /locus_tag="VYO88_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1720077.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1439..2044
                     /locus_tag="VYO88_002052"
     CDS             1439..2044
                     /locus_tag="VYO88_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1720078.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(1992..>2550)
                     /locus_tag="VYO88_002053"
     CDS             complement(1992..>2550)
                     /locus_tag="VYO88_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1720079.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          875 a          367 c          440 g          868 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagtga aataccagaa agttgggaat gggtgaggtt
       61 aaacgatata acctcctaca ttcaaagagg gaagtctcca aaatattcaa atattcctat
      121 ataccctgtg attgctcaga aatgtaatca atggtctggc ttttctattg acttagcaag
      181 atttattgat cccgaaacag ttcatagtta ccagaaagaa agattactaa gagatggtga
      241 tttaatgtgg aattcaacag gtctaggtac gttaggacga ttagctattt accatgaaaa
      301 taaaaatcct tatggctggg ctgttgcaga tagccatgtt acagttataa gagtcttatc
      361 gggagttatt aattgccatt tcatctataa ttttctttcc tctcctattg ttcagtcagt
      421 tattgaagaa aaagcgtcgg gtagtacaaa acaaaaagaa ttattaacga aaactataaa
      481 agaatattta atccccctcc caccccttcc tgaacaatcc agaatcgttg ataaaatcga
      541 acaatttttc gcccatattg acgcactaat ttagtataat agttttacgt gcggtggaat
      601 ttctatcaaa cataagatag gagttttacg ttgaaagatt ttgaattaca tttgaagaaa
      661 gctggtttag ctgaaaatac tgtgcgttcg tacctttatg gtgttcgatt tttcttggag
      721 aattacgaac tcaaaatgga agatttattt gaatacaaag gatatttatt agacaatttt
      781 aaacctaaaa ctgtcaattt gcgactacaa ggagtaaata aatatctggc ttttattggt
      841 catgatgatt tgaaattaaa atttgtcaaa gtacagcaaa aaccgttttt agaagatgtc
      901 attagccatg ctgattacct ttttcttaaa cgtagtttga aaaaagatgg tattttaaaa
      961 tggcattttg tcgtttggtt tttaggtgca actggggctc gtgtaagtga acttattaaa
     1021 ctaaaagtag agcatgtaga aatcggttat tttgacattt actcaaaagg tggtaaaatt
     1081 cgtagactgt acattcctaa aaaattaaga aatagttgtc ttagttggtt agaatcagaa
     1141 aatcgccgaa gtggttattt atttttgaat aaatttaacg aaccaattac agcaagagga
     1201 gttgctcaac agttaaaaaa ttatgctgat aaatacaaaa tgaatcctaa agtaatttac
     1261 cctcattctt ttaggcattt atttgctaag aattttttag cgaagtataa tgatattgcc
     1321 ttgcttgcag atttgatggg acacgaaagt atagaaacta ctcgaattta tctaaggaaa
     1381 acagctactg aacaacaaaa tattgtagat aaaattgtta attggtaaaa aataacaggt
     1441 ggtcaaactg actacctgct atttttgtga ttatggctct tattatggga atatacctat
     1501 gaattgggtt gttataaaaa taaaagatat tttttcaatg aatacaggtc tttcttacaa
     1561 gaagggcgat ttaagcatta ataataaagg tgttagaatt atacgtggtg gtaatattaa
     1621 gcctttagaa ttttctctgt tggataacga ttactacatt gatacacaat tcatctcctc
     1681 tgagcaagtt tatttaaaac ataatcagct aataacacct gtatcaacct ctttagaaca
     1741 tattggaaag tttgcaagaa tcgataaaga ctatgatggt gttgtggctg gtggatttat
     1801 tttccaatta acaccattcg aaagttcaga gattatttca aaatttctat tatttaactt
     1861 gtcctctccg ttattttata aacaattgaa agcaataact aaactatcag gtcaagcttt
     1921 atataatatt cctaaaacta cactaagcga gctattaatt ccgttagctc cttttgagga
     1981 acaggaactt attactcaaa aagttgagaa actttttgaa aaagtaaatc aactttggaa
     2041 atgattcttt tcatctcttc atgattagaa atagggatta ataattcgga gatactggta
     2101 ctatttaatg ttttcccttt gatagcatct tttgaatcac ctaaagtaga gataagtggc
     2161 aaaaatatca ttaagtaatc tctgataata ttttctttat tagcataggg gaatatcgat
     2221 ataatggctt cattatgagt ggcaggaata tccaatatgg caacttttcc aatagataat
     2281 ttaaaactca ttaataaagt tcctttaggt gaaatgtcta ttttctttga ttttaatgct
     2341 aatttagaaa tagattctct cgtattagtt acataaccag atataggcat atctgatata
     2401 gatacccaag gtatttcagt tccccaaaaa gtagcttcac tgcgtggagg agtttttcct
     2461 attctgaagt taactaggct agcaaattta atatatctcc atgcttctgg gatttcatat
     2521 ataggataag aggttgtttc gtctttattc
//
LOCUS       DAVLZS010000107         2079 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLZS010000107 DAVLZS010000000
VERSION     DAVLZS010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2079
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.108"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            119..2011
                     /gene="pepO"
                     /locus_tag="VYO88_002054"
     CDS             119..2011
                     /gene="pepO"
                     /locus_tag="VYO88_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1720080.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT          631 a          420 c          477 g          551 t
ORIGIN      
        1 ttttatcatg gaaagatttt ttataatagc taaaaaataa tagttaaatg gttattaatt
       61 gcattcccta gtgatttttg ttaagataaa tgcaaataca aatgaaagcg agaacaagat
      121 gacacgttat caagatgatt tttatgatgc tatcaatgga gaatggcaac agacagctga
      181 aatcccagca gataagtctc aaacaggagg ttttgttgat ttagaccagg aaattgaaga
      241 cctgatgctg gcgacaacag acaagtggtt agcaggtgaa gaagtgcctg aggatgctat
      301 cttggaaaac tttgtcaaat accaccgcct agttcgtgat tttgacaaga gagaagctga
      361 cggtatcaca cctgtcttac cactccttaa agaattccaa gaattggaga cttttgcgga
      421 ttttacagct aaactagcag agtttgagct tgcaggaaaa ccaaacttcc ttccttttgg
      481 tgtatcgcca gactttatgg atgctagaat caatgttcta tgggctagcg ctccaagcac
      541 aatcttgcca gatacgacct actatgcaga agaacatcct cagcgcgaag agctcttgac
      601 tctttggaaa gaaagcagcg caaatctcct caaggcttat gatttctctg atgaagaaat
      661 tgaagacttg ctagaaaaaa gacttgaatt ggaccgccga gttgcggcag tggtgctctc
      721 taatgaagaa agttcagaat atgctaaact ctatcatcca tattcttacg aagatttcaa
      781 gaaattcgcg cctgccctac ctttggatga cttcttcaaa gcagttattg ggcaattacc
      841 agacaaggtt attgtagacg aggaacgttt ctggcaagca gcagagcaat tctacagtga
      901 ggaagcctgg tctctcctta aagcaacctt gattttgagt gttgtcaatc tttcaaccag
      961 ctatttaaca gaggatatcc gtgttttgtc tggtgcctac agccgtgccc tttctggagt
     1021 tccagaggca aaagataagg tcaaagcagc ttatcatcta gcacaagaac ctttcaagca
     1081 agccctgggt ctttggtacg cccgtgagaa gttctctcca gaagccaagg cggatgtgga
     1141 gaaaaaagtg gcaaccatga ttgatgttta taaggagcgt ctgcttaaga atgactggct
     1201 cactccagaa acctgtaaac aggctatcgt gaagctcaat gtgatcaaac cttatattgg
     1261 ctatccagaa gaattgcctg cacgttacaa ggataaggta gtgaatgaaa ctgccagtct
     1321 ttttgagaat gctctagcct ttgcgcgtgt ggaaatcaag cacagttgga gtaagtggaa
     1381 ccagcctgta gattataagg aatggggcat gcctgctcat atggtcaatg cctactacaa
     1441 tcctcagaag aacctgattg tctttccagc ggccatttta caggcgcctt tctatgactt
     1501 gcatcagtca tcttctgcta actacggtgg tattggggca gtgattgccc atgaaatttc
     1561 ccacgccttt gatactaacg gggcttcctt tgacgaaaat ggtagcctca aggattggtg
     1621 gacagagagc gactatgctg ccttcaagga gaaaacacaa aaagtcattg accaatttga
     1681 tggacaggat tcttatggag caaccattaa cggtaaattg actgtatcag aaaacgtggc
     1741 tgacttggga ggaatcgcag cagcgcttga agcagctaag agagaagcag acttctcagc
     1801 agaagagttc ttctacaact tcggtcgcat ctggcgcatg aaaggtcgac cagaatttat
     1861 gaaacttttg gctagcgtcg atgtgcacgc accagccaaa ctccgtgtca atgtgcaagt
     1921 accaaacttc gacgatttct ttacaaccta tgatgtcaaa gaaggagacg gaatgtggcg
     1981 ttcaccagag gagcgcgtga ttatttggta atgcaaaaaa tctagtcatc agaaaaaagg
     2041 catccaatca tgtgtgaaaa ccttgatagg atgcctttt
//
LOCUS       DAVLZS010000108         1994 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLZS010000108 DAVLZS010000000
VERSION     DAVLZS010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.109"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            3..75
                     /locus_tag="VYO88_002055"
     tRNA            3..75
                     /locus_tag="VYO88_002055"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Val,seq:tac)
     gene            78..150
                     /locus_tag="VYO88_002056"
     tRNA            78..150
                     /locus_tag="VYO88_002056"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Asp,seq:gtc)
     gene            175..247
                     /locus_tag="VYO88_002057"
     tRNA            175..247
                     /locus_tag="VYO88_002057"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:208..210,aa:Lys,seq:ttt)
     gene            253..334
                     /locus_tag="VYO88_002058"
     tRNA            253..334
                     /locus_tag="VYO88_002058"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:287..289,aa:Leu,seq:tag)
     gene            353..425
                     /locus_tag="VYO88_002059"
     tRNA            353..425
                     /locus_tag="VYO88_002059"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:386..388,aa:Thr,seq:tgt)
     gene            448..519
                     /locus_tag="VYO88_002060"
     tRNA            448..519
                     /locus_tag="VYO88_002060"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:480..482,aa:Gly,seq:gcc)
     gene            527..612
                     /locus_tag="VYO88_002061"
     tRNA            527..612
                     /locus_tag="VYO88_002061"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:561..563,aa:Leu,seq:taa)
     gene            622..695
                     /locus_tag="VYO88_002062"
     tRNA            622..695
                     /locus_tag="VYO88_002062"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:656..658,aa:Arg,seq:acg)
     gene            711..784
                     /locus_tag="VYO88_002063"
     tRNA            711..784
                     /locus_tag="VYO88_002063"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:745..747,aa:Pro,seq:tgg)
     gene            790..863
                     /locus_tag="VYO88_002064"
     tRNA            790..863
                     /locus_tag="VYO88_002064"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:824..826,aa:Met,seq:cat)
     gene            877..950
                     /locus_tag="VYO88_002065"
     tRNA            877..950
                     /locus_tag="VYO88_002065"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:911..913,aa:Ile,seq:cat)
     gene            961..1050
                     /locus_tag="VYO88_002066"
     tRNA            961..1050
                     /locus_tag="VYO88_002066"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:997..999,aa:Ser,seq:tga)
     gene            1064..1137
                     /locus_tag="VYO88_002067"
     tRNA            1064..1137
                     /locus_tag="VYO88_002067"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1098..1100,aa:Met,seq:cat)
     gene            1141..1213
                     /locus_tag="VYO88_002068"
     tRNA            1141..1213
                     /locus_tag="VYO88_002068"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1174..1176,aa:Phe,seq:gaa)
     gene            1233..1303
                     /locus_tag="VYO88_002069"
     tRNA            1233..1303
                     /locus_tag="VYO88_002069"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1265..1267,aa:Gly,seq:tcc)
     gene            1339..1412
                     /locus_tag="VYO88_002070"
     tRNA            1339..1412
                     /locus_tag="VYO88_002070"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1373..1375,aa:Ile,seq:gat)
     gene            1419..1506
                     /locus_tag="VYO88_002071"
     tRNA            1419..1506
                     /locus_tag="VYO88_002071"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1453..1455,aa:Ser,seq:gct)
     gene            complement(1713..>1994)
                     /locus_tag="VYO88_002072"
     CDS             complement(1713..>1994)
                     /locus_tag="VYO88_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1720081.1"
                     /translation="KEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT          470 a          411 c          528 g          585 t
ORIGIN      
        1 tagggagttt agctcagctg ggagagcatc tgccttacaa gcagagggtc agcggttcga
       61 tcccgttaac tcccaaaggt cccgtagtgt agcggttatc acgtcgccct gtcacggcga
      121 agatcgcggg ttcgattccc gtcgggaccg tttaaggtaa cgcaagttat tttagactcg
      181 ttagctcagt tggtagagca attgactttt aatcaatggg tcactggttc gagcccagta
      241 cgggtcatat atgcgggttt ggcggaattg gcagacgcac cagatttagg atctggcgct
      301 taacggcgtg ggggttcaag tcccttaacc cgcattaaga tataacaaat gagccggctt
      361 agctcagttg gtagagcatc tgatttgtaa tcagagggtc gcgtgttcaa gtcatgtagc
      421 cggcattttt agatagaaga aaacagtgcg aacgtagttc agtggtagaa caccaccttg
      481 ccaaggtggg ggtcgcgggt tcgaatcccg tcgttcgctt agagaggccg gggtggcgga
      541 actggcagac gcacaggact taaaatcctg cgattggtaa cgatcgtacc ggttcgattc
      601 cggtcctcgg cataatatgg agcaccctta gctcaactgg atagagtacc tgactacgaa
      661 tcaggcggtt agaggttcga ctcctctagg gtgcattttt ctatttaact cgggaagtag
      721 ctcagcttgg tagagtactt ggtttgggac caaggtgtcg caggttcgaa tcctgtcttc
      781 ccgattcatg gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg
      841 gggttcgatc cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga
      901 gctctcggct cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt
      961 ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag
     1021 cgtgcgtggg ttcgaatccc acatcctcct tttatattat taacgcggga tggagcagct
     1081 cggtagctcg tcgggctcat aacccgaagg tcgtaggttc aaatcctgct cccgcaataa
     1141 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cggttcgatt
     1201 ccgtctcgcg ccattttatt gatagtattt atgcgggtgt agtttagtgg taaaactaca
     1261 gccttccaag ctgttgtcgc gagttcgatt ctcgtcaccc gctttgaact ttgttcaaat
     1321 taccaagttt tttaacttgg gcgcgtagct caggtggtta gagcgcatgc ctgataagcg
     1381 tgaggtcggt ggttcgagtc cactcgtgcc cattaattgg agaattactc aagaggctga
     1441 agaggacggt ttgctaaatc gttaggtcgg gtaactggcg caagggttcg aatcccttat
     1501 tctccgtttt aatgagagtt tgtaactctc ttttttattt ttagagacaa taaagcttca
     1561 gatccgtaaa acttaattga attactaatc tgaagttatt tttatggctc tttgtcaact
     1621 gtagtgggtt gaagaaaagc taagctcgag caaggacaaa tttcgtcctt tcttttttgg
     1681 ctctttgtca actgtagtgg gttgaaaaaa agctaagctc gagaaaggac aaattttgtc
     1741 ctttcttttt tgatgttcaa agcgataaaa atcctttttt tgaagttttc aaagttccga
     1801 aatccaaagg cgtttcgttt gataagtttg atgagattat ttgtcgcttc cagtttggcg
     1861 ttagaatagt gtagttgaag ggcgttgaca atcttttctt tatctttgag gaaggtttta
     1921 aagacagtct gaaaaatagg atgaacctgc ttcagattgt cctcaataag cccgaaaaat
     1981 ttctctggtt cctt
//
LOCUS       DAVLZS010000109         1993 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLZS010000109 DAVLZS010000000
VERSION     DAVLZS010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.110"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            158..295
                     /locus_tag="VYO88_002073"
     CDS             158..295
                     /locus_tag="VYO88_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV1720082.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDEMRFSTFSTNHCGNWSAFSWEN
                     C"
     gene            590..1941
                     /locus_tag="VYO88_002074"
     CDS             join(590..1031,1031..1941)
                     /locus_tag="VYO88_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1720083.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMIELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNSMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
BASE COUNT          694 a          297 c          430 g          572 t
ORIGIN      
        1 aagaatgcaa aaattatttc ttaaaaattt gtaagttttc gctatataaa atagttaaat
       61 ctattttgta taattgcttg cattttactg gtggagagaa tataatgagg gtggataaag
      121 tacttaatcc caaaaattta aataggagga gctagctatg gcagaagaag tattaaatct
      181 tcaattagta tctgttcaag ttgacgaaac agatgaagtt gatgaaatgc gatttagtac
      241 attcagtaca aaccattgcg gtaactggag tgcttttagt tgggaaaatt gttaattcat
      301 ttaaattgta aactttaggg attctctgga gttatggatg tcgttccaat atgtgtacgt
      361 tggaatgtta gtgcttatat gggggaacag aatcctctct tgattgaaga caagttagcc
      421 attaggctgg tttgtctctt tgtcaactgt agtgggttga tataatagta ttagtgagtg
      481 ggataaaagt ttcatttagt ttattcagta caaatttaac gggtcaagat tttatgaact
      541 gcaccccaaa agttagacag aaaaaatcta acttttgggg tgttttatta tgaaattgag
      601 ttatgaagat aaagttcaga tctatgaact aagaaagcaa ggacaaagct tcaaacagct
      661 ttcaaaaaga tttggtgtgg atgtttctgg tctaaagtac atggtgaaat taattgaccg
      721 ttatggcata gaaatcgtta aaaaagggaa gaatcgtcac tattcttcta aattgaaaca
      781 agaaatgatg gataaagcct tactggaagg ttgttcacaa agaagtatta gtcttgatta
      841 tgccctccca aaccaaggaa tgctttcatt ttggccggca caatacaaga aaaacgggta
      901 tactattgtt gagaaaacaa gagggagacc agctaaaatg ggacgtaaac ggaagaagac
      961 ttgggaagaa atgatagaac tagaacgact ccaggaggag aatgaacgct tacggactga
     1021 ggtggcctac ctaaaaaagt taaaagagtt agaggaaagg gacgaagccc tagagcgaga
     1081 aaggcagaga cagttagaga aatggtttca ggaggatttc gactagattt tcttcttgaa
     1141 acagcacgtt tagctcgctc gacttactat tatcagttga aacaactgga tggggttgat
     1201 aaagataaag agattaaaac cgaaattcag ggcattgata atgaacataa aggcaactat
     1261 ggctatcgtc gaatccattt agaactaagg aatcgtggtt ttgtggtcaa tcataagaaa
     1321 gttcaacggt tgatgagaat tcttggttta acggctcgaa ttcgccgtaa acggaagtat
     1381 tcttcctacc aaggagagat tggcaagaaa gcagagaatc tcattcaacg ccagttcgaa
     1441 gcatcgaggc caatggaaaa gtgctataca gatgtgacag agtttgccat tccaaatagc
     1501 acacagaaac tctatttatc accagtttta gatggtttta acagtgaaat cattgcttat
     1561 catctttcta cttcgccaaa cttagaacaa gtgaagagta tgttagaaca ggcctttaca
     1621 gagaaatact atgagaatac gattctccat agtgaccaag gctggcaata ccaacacgat
     1681 tcttatcatc ggttcctaga gagtaaggga attcaagcat ccatgtcacg caagggcaac
     1741 agcccagaca acagcatgat ggaatctttc tttggcattt taaaatccga aatgttttat
     1801 ggctatgaga agaactttag atctttagaa aaccttgaac aagctattgt ggactacatt
     1861 gattactaca acaacaaacg aattaaggta aaactaaaag gacttagttc tgtgcagtac
     1921 agaactaaat cctttggata aattatttgt ctaatttttt ggggtcagta cagtattaaa
     1981 taccatgatc tta
//
LOCUS       DAVLZS010000110         1923 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLZS010000110 DAVLZS010000000
VERSION     DAVLZS010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.111"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            141..1058
                     /gene="adcAII"
                     /locus_tag="VYO88_002075"
     CDS             141..1058
                     /gene="adcAII"
                     /locus_tag="VYO88_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1720084.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            1066..>1923
                     /gene="phtB"
                     /locus_tag="VYO88_002076"
     CDS             1066..>1923
                     /gene="phtB"
                     /locus_tag="VYO88_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV1720085.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLS"
BASE COUNT          647 a          342 c          404 g          530 t
ORIGIN      
        1 tgaaagtcta ttgagttgtt gacactcagc agatttttat atgtgaaaga aatttcaaat
       61 tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta ctagttaatt
      121 aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg ttaagtgtct
      181 ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag gggatgaaaa
      241 ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt gacttgaatg
      301 atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg gcaaatgata
      361 tcgcagccat ctatgatgca gatgtctttg tttaccattc tcatacactc gaatcttggg
      421 caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag gcttctgagg
      481 gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat ggagttgatg
      541 aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga gaagaagccc
      601 aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact tatcaaaaaa
      661 atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa ccaaaatttg
      721 aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat ctagcgaaga
      781 gatttgggct taatcaactt ggtattgcag gtatctctcc tgaacaagaa ccaagtccac
      841 gacaactaac agaaattcag gaatttgtta agacctataa ggttaaaacg atttttacag
      901 aaagtaacgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt gtgggtctta
      961 aaactctgaa tcctttagag tcagacccac aaaatgacaa gacctattta gaaaatcttg
     1021 aagaaaatat gagtattcta gcagaagaat taaagtgagg aaagaatgaa aattaataaa
     1081 aaatatctag caggttcagt ggcagtcctt gccctaagtg tttgttccta tgagcttgga
     1141 cgttaccaag ctggtcagga taagaaagag tctaatcgag ttgcttatat agatggtgat
     1201 caggctggtc aaaaggcaga aaacttgaca ccagatgaag tcagtaagag ggaggggatc
     1261 aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc tcatggagac
     1321 cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga agagctcctc
     1381 atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat caagggtggc
     1441 tatgtcatta aggtaaacgg taaatactat gtttacctta aggatgcagc tcatgcggat
     1501 aatattcgga caaaagaaga gattaaacgt cagaagcagg aacgcagtca taatcataac
     1561 tcaagagcag ataatgctgt tgctgcagcc agagcccaag gacgctacac cacagatgat
     1621 ggttatatct ttaatgcttc tgatatcatt gaagatactg gtgatgccta tatcgttcct
     1681 catggcaatc acttccacta tattcctaag agtgatttat ctgccagtga attagctgct
     1741 gcccaagcct attggaatgg gaagcaggga tctcgtcctt cttcaagttc tagtcataat
     1801 gcaaatccag ctcaaccaag attgtcagag aaccacaatc tgactgtcac tccaacttat
     1861 catcaaaatc aaggggaaaa catttcaagc cttttacgtg aattgtatgc taaaccctta
     1921 tca
//
LOCUS       DAVLZS010000111         1791 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLZS010000111 DAVLZS010000000
VERSION     DAVLZS010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.112"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            365..841
                     /locus_tag="VYO88_002077"
     CDS             365..841
                     /locus_tag="VYO88_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1720086.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            841..1602
                     /locus_tag="VYO88_002078"
     CDS             841..1602
                     /locus_tag="VYO88_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV1720087.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTT
                     SVADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT          660 a          239 c          347 g          545 t
ORIGIN      
        1 agtaaaaaca acactttatt gaggtattgg atacgctttg ctaatagcct aataatcaca
       61 tgtggagtgt tgctacaacg aaaaaggcga taatccttga tttcaaacta ttttataagc
      121 attttgtctt tgtagataaa ggcaattttg acaataaaaa tcctaaaagg tgaatcgtta
      181 tagatgtatt tgtagatatc gtttgcgcat cgaaaaaatt aatacaagaa taaatattta
      241 tggctcttta ggtgactttt atagaagtaa agtttaggat agaaacacaa gaaataacgc
      301 accatttttg gtgcgttatg cttttttatg ctataatgga tttataaaaa taaaggagtt
      361 tgctatgatt ggaaagaaca taaaatcctt acgtaaaaca catgacttaa cacaacccga
      421 atttgcacga attataggaa tttctcgaaa tagcttgagt cgttatgaaa atggaactag
      481 ttcagtctct acggaattaa ttgacatcat ttgtcagaag tttaatgtat cttatgtcga
      541 tattgtagga gaagataaaa tgctcaatcc tgttgaagat tatgaattga ctttgaaaat
      601 tgaaattgtg aaagaaagag gagctaatct attatctcga ctctatcgtt atcaagatag
      661 tcagggaatt agcattgatg atgaatctaa tccttggatt ttaatgagtg atgatctatc
      721 tgacttgatt catacgaata tctatttagt agaaactttt gatgaaatag agagatatag
      781 tggctatttg gatggaattg aacgtatgtt agagatatct gaaaagcgga tggtagctta
      841 atggaaatcc aagattatac tgatagtgaa ttcaaacatg ctttagcaag gaatcttcgt
      901 tcactgacaa gaggaaaaaa gtccagtaag caacctatag cgattttgct tggagggcaa
      961 agtggtgccg gtaagactac aattcatcgt attaaacaga aagaatttca aggaaatatt
     1021 gttatcatag atggtgatag ttttcgttct cagcatccac actatttaga actgcagcaa
     1081 gaatatggca aagacagtgt agaatatacc aaagattttg caggaaaaat ggtagagtct
     1141 ttagtaacaa aattgagtag tttgagatac aatcttttga tagagggaac tttacgaaca
     1201 gttgatgttc caaagaaaac agcacaactc ttgaaaaata agggatatga agtacaattg
     1261 gccttaattg cgacaaagcc tgaattgtcg tatctaagta ctcttatccg ttatgaagaa
     1321 ctgtacatta tcaatccaaa tcaagcacgc gcaactccaa aagaacatca tgatttcatt
     1381 gtaaatcatc tagttgataa cacacgaaaa ttggaagaac tagctatctt tgaaagaatt
     1441 caaatttacc aacgagatag aagttgtgta tatgattcaa aagaaaatac aacttcagta
     1501 gcagatgttc ttcaagagtt actctttggg gagtggagtc aggtagagaa ggagatgttg
     1561 caggtggggg aaaagagact taatgaatta cttgaaaaat aaacaattga tatttttagg
     1621 agaatagaaa tgagagggtt taataacaag ataaagtctg tttatcaaga actaacaaat
     1681 tccaaagaga aattcggtag ctttcacaag actttaattc atttgcatac acctgtttct
     1741 tatgattaca agctattttc taattggact gcaacgaaat atagaaaaat t
//
LOCUS       DAVLZS010000112         1730 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLZS010000112 DAVLZS010000000
VERSION     DAVLZS010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1730
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.113"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            13..1014
                     /locus_tag="VYO88_002079"
     CDS             13..1014
                     /locus_tag="VYO88_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1720088.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT          575 a          233 c          351 g          571 t
ORIGIN      
        1 tggaggactg aaatgaaaaa tataaatggg aaaaaggtaa ctatttatga tattgcacgt
       61 ttatcaggtt tttctccaaa aacagtttca cgagttatta atggtggagt aaatgttaaa
      121 gaagaaactt atcaagcgat tcaaaaagtt atagaggaat tgtcgtatat tccaaatgcg
      181 tatgcaaaaa atttaactaa aaaagaagct ataaatatat tgatttctgt aaaaaaaatc
      241 gactcttttc ctttaatttg gtttcatacg ctgttagata aagtgttacg gacgtgtaaa
      301 gaatttggtg ttaatgctat agttgagtac tttggagagg aggatacaat tagtaattca
      361 attatatcaa gcacaggtag cctagtagat ggtgttattg ttttttatga aagtgtagat
      421 gatatcagaa ttcagtattt aaagaagaac catatgcctt ttcttgtttt cggtgaatct
      481 caaacgtctg gagtagtcta tgtatctaat aataattttc aagctactta tgatatgatg
      541 aaagctgtaa ctgaagaaaa atttaaaaat atgtggttgc ttatgggggg agaatcccat
      601 gttaataagg atcgtgaaag aggtgtgcgt tcttttctga atgataaaaa ttactttatg
      661 gatttaaaag tcatttatgg cttatctaca attgattcag tttattctta tgcaatgcag
      721 cacttgacta cccaaaatta tccggacatt atttttgttt caggagatga aaaggttcag
      781 ggcttgattc gtgcgtgcta tgagaaagga attcttattc cagatgatat ttctattatt
      841 ggatttgata atattcctat ttctcagtat tatactccag ctttgtctac aattgctccc
      901 aattatgtta aattggctaa agaaatgata gaaggtgttt tagcaattat taaaggggaa
      961 agtgtcacat ctgttgaagt ttctcctaaa tttgttagga gacagagttt ctagtattgt
     1021 ttaattcttg aaaatcctag tggaaaagat ggagtgttct aaaataagtt ctgtttagcc
     1081 tccattcagt ttctattgag ttggatccaa tttctaacaa gtgggacatg ttcatgttcg
     1141 atctaaggaa gacatggtca cattcgaatg atattttcaa aaaaatcgta aaaaagtctt
     1201 gacaaagaaa aaacaaagta ttaaaataag ttcaacaaat cagaaaagta actatttttg
     1261 atcttcaggg agcctgtggt gattgtgaat aggtggttgg aagtagtgaa agtgggctga
     1321 ttttgaaaat gaatttgaaa caatgaaaat tcggtgcgca caccttacag tgcagcttgt
     1381 tgttaaacaa ggcagagatg taaagggata gtccctttat aattgaggtg gcaccgcgtt
     1441 accaacgccc tcacacggaa gtatattctg tgtgtgggct tttttctatc cgtcgtttgg
     1501 tttatctttt attagggcct taagtcgctt tgatgaactt gagttctatc tacagctcct
     1561 tgcctactac taaaagcaaa caaaaagctg gactaatacg aaaaaagcta gtgatactca
     1621 atgaaaatca aagaacaaac taggaaacta gccgcaggtt gctcaaaaca ctgttttgag
     1681 gttgtggata aaactgacga agtcagctca aaatactgtt ttgaggttgt
//
LOCUS       DAVLZS010000113         1672 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLZS010000113 DAVLZS010000000
VERSION     DAVLZS010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.114"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            58..1548
                     /locus_tag="VYO88_002080"
     CDS             58..1548
                     /locus_tag="VYO88_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1720089.1"
                     /translation="MNLERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRN
                     RVATDISNSTYQEFHSKSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTL
                     NHYHWSLTVATLFSLMIMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLA
                     SLNLLYVLPKKIKEAGILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIK
                     GIVKIGTIEAIGALTGVIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEP
                     NEVNRDFPLYEAKNICYKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGF
                     LRDYSGELRFCGDDIKKTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQ
                     SLEQVGLSVKDFPNNILDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAI
                     DRRTSLAIERKILDREDLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          583 a          197 c          319 g          573 t
ORIGIN      
        1 ttattgctaa tttatgcagc aactattaat gctctggtgt tgaatgaatt aattgcgatg
       61 aatttagagc ggtttttgaa attgtcaatc taccaaatga ttgtctggtg tgggataata
      121 ttccttgact gggtagtgaa aaattatcag gttgaagtga tccaagagtt taatctagag
      181 attcgaaata gagttgccac agacatctct aactctacct atcaagaatt tcatagtaaa
      241 tcatcaggaa catatctttc gtggctaaat aatgacgttc agactttaaa tgatcaggct
      301 tttaaacaac tttttttagt aataaaagga atttctggta ctatatttgc agttgtgact
      361 cttaatcact atcattggtc attgactgta gccaccttgt tttcattaat gattatgcta
      421 cttgtaccaa aaatctttgc atcgaaaatg cgagaagtta gtctaaattt aactaaccaa
      481 aatgaagctt ttttaaaatc tagtgagact atattgaatg gatttgatgt gttagcgtcc
      541 ttgaatcttt tatatgtatt gcctaagaaa attaaagaag caggaatttt attaaagatg
      601 gttatacaaa gaaagacaac tgtagaaacg ttagcaggcg ctattagctt ctttctcaat
      661 attttttttc agatatctct cgttttttta acaggctatc ttgcaataaa aggaatagtg
      721 aaaattggta ctattgaagc aataggagca ctaacaggtg ttatttttac agcgctaggt
      781 gaattaggag gtcaattatc ctctattatt ggtacgaagc ctattttttt aaaattgtat
      841 tcaattaatc caattgagtc aaataaaatg aatgatatcg aaccaaatga ggtgaataga
      901 gattttccgt tatatgaagc aaaaaatatt tgctataagt atggagataa agaaatatta
      961 aaaaacttaa atttttgttt tcaacgtaat gaaaagtatt taattttagg tgaaagtgga
     1021 agcgggaaat ctacattatt aaaattattg aatggctttt tgagagatta tagtggagaa
     1081 ttgcgattct gcggggatga tataaaaaaa acctcctatt taaatatggt ttcgaatgtt
     1141 ctatatgtag atcaaaaagc ttatttgttt gaaggtacga ttagagataa tattttattg
     1201 gaagaaaatt atactgatga agaaatacta cagtctttag agcaagttgg tttgagtgta
     1261 aaagattttc ctaataacat tttagattat tatgttggtg atgatgggag attactgtca
     1321 ggagggcaga aacaaaaaat tactttagct agagggctaa ttagaaataa gaaaatagta
     1381 ttaattgacg agggaacttc tgctatcgat aggagaactt cgttagcgat tgaacgtaag
     1441 atattagata gagaggattt gactgtcatt attgttaccc atgctccgca tccggaactt
     1501 aaacaatatt ttactaagat atatcaattt ccaaaggatt ttatttaaga atatagggga
     1561 gggaaacatg agattctatt gtgaagctta tgaggtaatt actgaagaga aaaaagtata
     1621 ctttaatgat attgagttag aagttaagta ttcctctgtc gaagaattgt tt
//
LOCUS       DAVLZS010000114         1614 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLZS010000114 DAVLZS010000000
VERSION     DAVLZS010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.115"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..>1614
                     /locus_tag="VYO88_002081"
     CDS             <1..>1614
                     /locus_tag="VYO88_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HEV1720090.1"
                     /translation="TTDLLQLKSCIEKYSKSELGEGILQYAEICEKMSHIFNEEKQRY
                     LKVDLVNSYDSLLPKDLKKTLEDFVNFISRINLGKDYRNKELISYTEKFVEKYGEYVE
                     VPIKQLLDSKLGLGIPKQNLEPYSILSSVAEQTFLSYLSKEIFKAVKNNKKEIDISNI
                     PPELLYPNLDRFAVNQFELYCEMKNFGEQPVISIVPNTGSDMIGKSIGRFASYFLNSN
                     IELDSRVDNVELIEFPSDNKNLNVMSSHHGHSKKLLLSYEDDFDIDSLELDFLVVGVE
                     RVNEHYKLYFRDLRTDLIVNFVTTSMLNHKSIGVFSHLARFLLTVSLEWQDNPFSLFR
                     VIENLDFLPYIPRIKYKNIILSEEKWILSDVDKKDMSTISQWKKFFDVPSLLYFHKDD
                     ERLLIDLKNSLDVQWILKQNVDKLHFTRFDKIDGKNCEFIFGFENPRNSVYPHSVSEK
                     TVRRIENDFYKDYVKTFSSDWIYFKLYGINSSTMPELRENLLIFTDELLAEKLVSDFH
                     FVNYNDGGDGSIRLRFKIMNEDDFEKLRY"
BASE COUNT          575 a          183 c          294 g          562 t
ORIGIN      
        1 taactactga tttgttacaa cttaaatcat gcatcgagaa gtattcaaaa tcagagttag
       61 gagaaggtat tcttcaatat gctgaaattt gtgaaaaaat gtctcatatt tttaatgaag
      121 aaaaacagcg ctatctgaag gttgacttag tgaatagtta tgattcgcta ttacccaaag
      181 atttaaaaaa gacattggag gacttcgtta actttatttc gagaattaat ctgggtaaag
      241 attatcgaaa taaggaatta atctcgtaca cagaaaaatt tgtcgaaaaa tacggagagt
      301 atgttgaagt tcctattaag caactactgg atagtaagtt agggttgggg ataccaaaac
      361 aaaatttgga accttatagt atattatcaa gtgttgcaga acaaactttt ttgtcttatc
      421 taagtaaaga aatctttaaa gcagtgaaaa ataataaaaa ggaaattgat atatcaaata
      481 ttccgcctga attattgtat ccaaatttgg atagatttgc tgtgaatcag ttcgagttgt
      541 attgtgaaat gaagaatttt ggagaacaac ctgttatatc aattgtgcca aatactggga
      601 gtgatatgat aggaaagtct attggtagat ttgcttcata ttttctaaat tctaatatag
      661 aattagattc gagggttgat aatgtagaat taatagaatt tccaagtgat aataaaaatt
      721 taaatgttat gtcttctcac catggacatt ctaaaaagtt attactatct tatgaagatg
      781 actttgatat tgactcgtta gaattagatt tcttagtagt gggtgttgag agagtgaatg
      841 agcattacaa actatatttt agagacttac gaacagactt gattgttaat tttgtaacaa
      901 cctcaatgct gaatcataaa tctatcggag tttttagcca tttagcgaga tttttgttaa
      961 cagtttcgtt agagtggcaa gataatccat tttctctatt tagggtaatt gagaatcttg
     1021 atttccttcc ttatattcct agaattaaat ataagaatat tattttaagt gaagagaagt
     1081 ggattttatc agatgtcgat aaaaaagata tgtctactat tagtcagtgg aaaaaatttt
     1141 ttgatgtacc tagccttcta tactttcata aagatgatga gcgtttactg attgacctaa
     1201 agaatagttt agatgttcaa tggattttaa aacaaaatgt tgataaatta cattttacgc
     1261 gttttgataa gattgatggt aaaaattgcg agtttatctt tggatttgaa aatcctcgaa
     1321 atagtgtata ccctcattca gtaagtgaaa aaactgtcag aagaattgaa aatgactttt
     1381 ataaagatta tgtaaaaacg ttttcgagcg attggatata tttcaaatta tatggaatta
     1441 actcctcaac gatgcctgaa ctaagagaaa atcttcttat attcactgat gagcttttag
     1501 ctgagaaatt agttagtgat tttcattttg taaattataa tgatggcggg gatggttcta
     1561 ttagattaag gtttaaaatt atgaacgaag atgattttga aaagctaaga tatc
//
LOCUS       DAVLZS010000115         1586 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLZS010000115 DAVLZS010000000
VERSION     DAVLZS010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.116"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..740)
                     /locus_tag="VYO88_002082"
     CDS             complement(<1..740)
                     /locus_tag="VYO88_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720091.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFVQ
                     SYLGSNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLL"
     gene            complement(897..1106)
                     /locus_tag="VYO88_002083"
     CDS             complement(897..1106)
                     /locus_tag="VYO88_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720092.1"
                     /translation="MFFAGIGEIHFLLFLLYLSMSASPIIGLVIGYTKINLINSIIIA
                     LGMILALILVLSRVYRKYFYRDDDD"
BASE COUNT          606 a          275 c          198 g          507 t
ORIGIN      
        1 taaagcaaag gtaaaacttt ataaaaaata tctaagtcaa cctcactctg attctgaagc
       61 aagtaggagt caagcaaatt ttcaaaaata gctatcaata tgattggtgt aaggtttttg
      121 tattcacatg tcaagtattc tgagtatcgt gcagatgata tttcttttat ataacttttt
      181 gaaagcaaga ttttttcaaa ttcatcatct attattaatc ttctatttcc aatccaagcg
      241 gtattgctac ccaaataaga ttgtacaaat agcaatatgt aagaaaacat gaacgtaaat
      301 actgaaagag gtagaattct atgcgtaaaa aaatagacga taatggtagc caggagtaaa
      361 gctatctctc gtgacaatcg aattcttttc agcatctttt ttaacagtcc gtaaggttgt
      421 ccttggcaat attcttgaac taaattaatc ggaatgacat ctctcaccat ttctggaaag
      481 tagagtaagt ttataggttg aaatctccag ctcccatcat aagtaaatgg atatagaacc
      541 aaatacttaa aagatttttt tcttataaac ttaattatca caatatgaat gactgttcca
      601 atgaagtata ttaaatataa aagtaaaacc gccatcaata tacttacaaa aatccccttg
      661 gaatcaatca atggaaaata aaatattgca actagaagcg aataaagtcc cgctaataaa
      721 tatttctgat catctttcat ttaaaacacc atattattta ctaagaatgc atcaatacaa
      781 tagagcaact ctgtaagtca atatttgata aagcaaagct ttaaaccctt ccccagacgt
      841 tagcttttat tcaacccact acagttgaca aggagcccaa attattgata aaaactttag
      901 tcatcatcgt ctctataaaa atattttcta tacactcttg ataataccaa aattaatgcc
      961 aatatcatac caagagctat aataatagaa tttattagat ttattttagt atatccaatc
     1021 actagtccaa taattggact agcagacatg cttagatata ataaaaataa caaaaaatga
     1081 atttcaccaa ttcctgcaaa aaaaatgttt catagctata gttttacgcc cataaatacc
     1141 catcaaattt accgtctacg atatctaaac catatgcaat ggctcctcct aatgagaaga
     1201 cttcagcaac agtagccgca atattaagag cattagtaat agttgccata ctaactccac
     1261 caatatatct tgttatagca cttagttacc tagataagat atcctttagc ttgcttccaa
     1321 aatttaagtc tgcacctata atatgagttc atattagtac tgctaaatcc tatctatagt
     1381 aatgtcaaac acctaaataa agtcatctct ccaattcatt caagaaatga agaaaggcaa
     1441 aaaatcttta aaataagaaa aatgcatatt atcaggtgtt caaaaatatt gatgatatac
     1501 gttatataga tagaaagatt tactcaatct cattttcaaa ttgagttttt tcccaacctc
     1561 gtttttaatt tatatcttca ataaaa
//
LOCUS       DAVLZS010000116         1402 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLZS010000116 DAVLZS010000000
VERSION     DAVLZS010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.117"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            81..1046
                     /locus_tag="VYO88_002084"
     CDS             81..1046
                     /locus_tag="VYO88_002084"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1720093.1"
                     /translation="MAIIKKIVVLYGGLSEEREVSENSAKEISKSLLTLGYDVISIDL
                     SQDCSYEIGEIEKSERGLNKQKAEIGSGIIDVCRKVDIVFLATHGGIGENGKLQAIFD
                     VEKIDYTGNSFLSTAISMDKKLSKIVASSVGIKCASNLMVDRIQANDFPIVIKPIRSG
                     SSKGIKILQNKKQFDIYYKEHPELGSFFVEKYIKGREFSVGILGETVLPVIEIKVKNG
                     FYDYNNKYTVGAAEEVVPAKISEKLTHTLQKSAYKIHKALGFNVYSRTDFIVDEKGDV
                     YFIESNSLPGMTKTSLLPQEAKAAGIDFPNLCERIIELSREIRSQ"
     gene            1111..1347
                     /locus_tag="VYO88_002085"
     CDS             1111..1347
                     /locus_tag="VYO88_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720094.1"
                     /translation="MKIINGICRYIFDSKGFATIEVEIFLDSGDTGIGAAPRGSTTGR
                     YDIQYNEYYPRGNNFSPIPDGHIEFFRLYNICSG"
BASE COUNT          506 a          161 c          285 g          450 t
ORIGIN      
        1 ctataatatt tattatttat attttgagat aactattgct tcattttatt caataagatt
       61 ctaataagga ggttaagtga atggctatta ttaaaaaaat tgttgtacta tatggtggcc
      121 ttagcgaaga gagagaggtg tcagaaaatt ctgcaaagga gattagtaaa agtctattaa
      181 cattggggta cgatgtgatt tctatagatt tatctcaaga ctgttcgtac gagataggag
      241 aaattgaaaa aagtgagcgc ggattaaata aacaaaaagc tgagattggt tcgggtatta
      301 ttgatgtttg tagaaaggtt gatatagttt tcttagcaac tcatggcgga ataggtgaga
      361 atgggaaact acaggctatt tttgatgtag aaaaaataga ctatacagga aattcgtttc
      421 ttagtacagc tattagcatg gataaaaaat tatcaaaaat agtggctagt tctgttggaa
      481 taaaatgtgc ttcgaacttg atggttgata gaattcaggc aaatgatttt cctattgtta
      541 taaagccaat tagaagtggt tcaagtaaag gtattaagat acttcaaaat aaaaaacaat
      601 ttgacattta ttataaagag catcctgaac ttggttcatt ctttgtagaa aagtatatta
      661 aggggagaga attttcggta ggtattttag gtgaaactgt tttaccggtt attgaaataa
      721 aagtaaaaaa tggtttttat gattataata acaagtacac tgttggtgca gctgaagaag
      781 tcgttcccgc aaaaatatct gaaaagttaa ctcatacctt acaaaaatcc gcatataaaa
      841 tacataaggc tcttggattt aatgtttatt cacgtactga ttttattgta gatgagaagg
      901 gggatgtata ttttattgaa tcaaatagtt taccaggtat gactaaaaca agtttattac
      961 cacaggaagc gaaagcagct ggtatagatt tcccaaacct atgtgaacgt attattgagc
     1021 tgagtaggga aattagatct caatagaaaa taaaatcgac gacatttata aaaaagtaat
     1081 tttcaatgat aaaaaagaaa gtggaagcct atgaaaataa ttaatggtat ttgcagatat
     1141 atctttgact caaaagggtt cgcaacaatt gaagtagaga tttttcttga tagtggagat
     1201 actggaattg gtgctgctcc acgagggtct acaactgggc gttatgatat tcaatataat
     1261 gagtattatc ctagaggaaa taactttagt ccaataccag atggacatat agaatttttc
     1321 aggctctata atatttgtag tgggtaaatc ccctatggat attatggagc ctattttgtg
     1381 tagaaaaaaa gtcccatatg ac
//
LOCUS       DAVLZS010000117         1402 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLZS010000117 DAVLZS010000000
VERSION     DAVLZS010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.118"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            16..>1402
                     /gene="pcpA"
                     /locus_tag="VYO88_002086"
     CDS             16..>1402
                     /gene="pcpA"
                     /locus_tag="VYO88_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV1720095.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT          549 a          195 c          226 g          432 t
ORIGIN      
        1 tgtaaggaaa tttaaatgaa aaaaactaca atattatcat taactacagc tgcggttatt
       61 ttagcagcat atgtccctaa tgaaccaatc ctagcagata ctcctagttc ggaagtaatc
      121 aaagagacta aagttggaag tattattcaa caaaataata tcaaatataa ggttctaact
      181 gtagaaggta acataggaac tgttcaagtg ggtaatggag ttactcctgt agagtttgaa
      241 gctggtcaag atggaaaacc attcacgatt cctacaaaaa tcacagtagg tgataaagta
      301 tttaccgtta ctgaagtagc tagtcaagct tttagttatt atccagatga aacaggtaga
      361 attgtctact atcctagctc tattactatc ccatcaagca taaaaaaaat acaaaaaaaa
      421 ggcttccatg gaagtaaagc taaaactatt atttttgaca aaggcagtca gctggagaaa
      481 attgaagata gagcttttga tttttctgaa ttagaagaga ttgaattgcc tgcatctcta
      541 gaatatattg gaacaagtgc attttctttt agtcaaaaat tgaaaaagct aaccttttcc
      601 tcaagttcaa aattagaatt aatatcacat gaggcttttg ctaatttatc aaatttagag
      661 aaactaacat taccaaaatc ggttaaaaca ttaggaagta atctatttag actcactact
      721 agcttaaaac atgttgatgt tgaagaagga aatgaatcgt ttgcctcagt tgatggtgtt
      781 ttgttttcaa aagataaaac tcaattaatt tattatccaa gtcaaaaaaa tgacgaaagt
      841 tataaaacgc ctaaggagac aaaagaactt gcatcatatt cgtttaataa aaattcttac
      901 ttgaaaaaac tcgaattgaa tgaaggttta gaaaaaatcg gtacttttgc atttgcggat
      961 gcgattaaac ttgaagaaat tagcttacca aatagtttag aaactattga acgtttagcc
     1021 ttttacggta atttagaatt aaaagaactt atattaccag ataatgttaa aaattttggt
     1081 aaacacgtta tgaacggttt accaaaatta aaaagtttaa caattggtaa taatatcaac
     1141 tcattgccgt ccttcttcct aagtggcgtc ttagattcat taaaggaaat tcatattaag
     1201 aataaaagta cagagttttc tgtgaaaaaa gatacatttg caattcctga aactgttaag
     1261 ttctatgtaa catcagaaca tataaaagat gttcttaaat caaatttatc tactagtaat
     1321 gatatcattg ttgaaaaagt agataatata aaacaagaaa ctgatgtagc taaacctaaa
     1381 aagaattcta atcagggagt ag
//
LOCUS       DAVLZS010000118         1329 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLZS010000118 DAVLZS010000000
VERSION     DAVLZS010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.119"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..483)
                     /locus_tag="VYO88_002087"
     CDS             complement(<1..483)
                     /locus_tag="VYO88_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1720096.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     K"
     gene            complement(480..962)
                     /locus_tag="VYO88_002088"
     CDS             complement(480..962)
                     /locus_tag="VYO88_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEV1720097.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
BASE COUNT          516 a          224 c          155 g          434 t
ORIGIN      
        1 tttcatggaa attaagcgtt tagcaatcat atcaatactt cttgcatcca ctgttgataa
       61 agtctcatca ataaaaatat aatcccaatt tttagcaaaa attaaggata agcctaattt
      121 gaattttgtt ccagtagatg ctgtcatata gttatctccg attttattat caaaaaaagt
      181 atttatttgt tctttatcct caaatgatag atggatttga aaagaatcac acaacaactg
      241 caaattttct tctatagtaa atggaacaac cccaagctga ttggtatcaa ggtatagtac
      301 atctttggag acacaattct ttaaaccact atcaaaagtc tctagcccag ctaaaagttg
      361 tagaagggtg ctctttcctg aaccattctc tccttcaact ctgtaaattc ccttatcaat
      421 ctctagtgat atatttttca atatacattt atcataactt ttagattcat tttcaatttt
      481 cataatttaa ttccctctat caacgctgct aaaattaata aaagataaga aatgatatac
      541 cattttaaat tactttttat ataaataagt atatttttaa ttcccctatc cttcaataat
      601 cggtataaaa gatactgact cataccttga taccaaataa aattcggtat ttcaataaga
      661 gcatgaggta atattccttt tattgtagct actattccaa tcatctgacc agatataccc
      721 aattgtattc ctaaagatag caaatcaaaa agttgcaata agggcgaaat cggaaaacag
      781 aatagatata gcaaaaaatt tgtagaattt gcctgtaaaa ctgtcaatgt aaattgtaat
      841 tccagtttcg gaggtatagt agcaaaagtc tcatttttta atataaagct taaaagtaaa
      901 cctagtaaaa aacagactat acaaaataac acatagtaaa tcagaaaacc actttttctc
      961 atctaatgcc ccctactaaa attacaaata ttatcagaaa acaatataaa accagaaaac
     1021 tccatctcaa taaactaact gtacctttaa ttaaaaatag agctttctta taatagacat
     1081 aggctataaa ataattgaat ggaatcaata acaaattcaa caaaatactt tttatatcat
     1141 tactataact tgtcaccgga atcaaacata acaacaatga aaattgtaag aaagagatta
     1201 aatgcgtcaa catcattagt tgtgcattct taaaaaagaa attcatttta gaatgattaa
     1261 gagcagataa ttgaagtaaa gctagatcta ccccaattga ggatttatga ttccctatta
     1321 ttgcctcca
//
LOCUS       DAVLZS010000119         1265 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLZS010000119 DAVLZS010000000
VERSION     DAVLZS010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.120"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..707)
                     /locus_tag="VYO88_002089"
     CDS             complement(<1..707)
                     /locus_tag="VYO88_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720098.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKR"
     gene            complement(1022..>1265)
                     /locus_tag="VYO88_002090"
     CDS             complement(1022..>1265)
                     /locus_tag="VYO88_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720099.1"
                     /translation="IIYDNEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVI
                     NEFIACLNSRCVPSQYDRFFYKDRPYIFSRKSSIKG"
BASE COUNT          460 a          214 c          174 g          417 t
ORIGIN      
        1 cgcttaactt ctaataaatc aatttgttca cgcacactct ctgaaagata tggcttgatt
       61 aaactgatat aagataaagc cacgcatggc aactcagatt ttgattgcaa tttccaaatt
      121 tcatgataat cctgaagatt aaactcacaa ttcttcttag attccagtat tgttagtacc
      181 tttgatttta acagaaataa ttgttgattc tcaattctat aaagtttttg tactaatgct
      241 atgataatag aaaatgaaat aagaggcaaa agcaacggtt tgtcatacac aaaagtaaag
      301 aaaaaatagt atgaaattag tgttgtaaag tacaagaagt agtaaaattt aaacagattc
      361 ttagttgttt gactctcctt ataaaacact gctattcctg gactaaatcc cattagttgg
      421 tgaaagagaa ttcgatagta tttcctagct cctataatga tcacaaatat aaaataaaaa
      481 taaattggtc ttaatttaca aaagattgag gaaactagta atagcaaagt atgtaagcat
      541 tgagacaaaa tatagaataa cggtatcgcc aatacaaagg ttaagatggc atgagagggg
      601 gttcctaaga tgtccaattt tataaatact gggctgacac aaaatatcgt gcttataagc
      661 agtaaaatca ttaaaattgt gtcaaaaaaa taacgcttat ttttcattta gtctactttc
      721 cattgttaaa taatactact gctaacacca agccaactta gcacattgca tcacctaatc
      781 ctgcgctact tgtccataat cctttaatgt ttctactaaa attattccaa tttcccccat
      841 caagatagct tatttatcct agacaatgcc tactgcaaca gtataaataa gattcatcag
      901 ccatcttttc tggcaatcat atgggtagcc taatgatatt tctagttact caaaaatatc
      961 tagctatact agagttattt ctaatcccta ggacacttgt taatccaaat ataacaaatt
     1021 ttcacccctt aatagaactc tttctggaaa aaatataagg tctatcttta taaaaaaatc
     1081 tatcatattg ggatggcacg catctggaat ttaaacaagc tataaattca tttataacta
     1141 ctatttgttt agaggcaaca gcatcttgta taccgccctc gaaagaacca tcttgtaatt
     1201 ccgaaatatt tttgtttaaa tattgttttg acaaatctct taatgcttca ttatcgtaaa
     1261 tgatt
//
LOCUS       DAVLZS010000120         1220 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLZS010000120 DAVLZS010000000
VERSION     DAVLZS010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.121"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..386
                     /locus_tag="VYO88_002091"
     CDS             <1..386
                     /locus_tag="VYO88_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720100.1"
                     /translation="LEDFFIEMILDIQGIPEYSKHLLNLSLTNTGDIKEYFQQHFPLA
                     SSSYNELKDKFIDFTYNQFDTIEILENDSVFLFRKKDSVTLSPKNKESYLSYQKLPEK
                     LDLLAKYILLPMIDKLTLESLIYRK"
     gene            571..1008
                     /locus_tag="VYO88_002092"
     CDS             571..1008
                     /locus_tag="VYO88_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720101.1"
                     /translation="MENNFGKVSFNSPSLKNLLIGTSNVEHTPTSAFVIECRDVPKRN
                     EKNEVIDGTISKKVLLALQSEIVKAIQEVGGDLSSIKPFTIEIYNDESFLKKINNELI
                     IAKTIDLEGALLALKWVSDGRNGGAYREFKLIISEIKLSGAKS"
BASE COUNT          455 a          168 c          186 g          411 t
ORIGIN      
        1 atttagaaga tttctttatt gaaatgattc ttgatattca aggaatacca gaatattcta
       61 agcacttatt gaatttatca ctaacaaata caggagatat caaagaatac tttcaacaac
      121 attttccttt ggcaagttct tcttacaatg aattaaaaga taaatttatt gattttacct
      181 ataatcagtt tgatactata gaaattttag aaaacgattc agtattttta tttaggaaaa
      241 aggactctgt cacactatca cctaaaaata aggaatctta tcttagctat caaaaacttc
      301 cagaaaagtt agacttatta gcaaagtata ttttattacc aatgatagat aaactaacac
      361 tcgaaagttt aatttatcgt aaataataaa atttttattt agtactgtat agcatatttt
      421 ccccacttcg cgtggggatt tttttgttgt caaaaaattt ttatccccac atttcaacta
      481 attaaaaatg agacaatatg actgtcaagg aggtcatgaa ctgcttgatg aaattaatct
      541 agtgtgcaca caaagataaa gaggtaacaa atggaaaata attttggaaa agtgagtttt
      601 aactcaccaa gcttgaaaaa tctactaatt ggtacgtcca atgtagaaca tactcctact
      661 agtgcttttg ttattgaatg tagagatgtt cctaaacgta atgaaaaaaa tgaagtcatt
      721 gatggaacaa taagtaaaaa agttttattg gctcttcagt cagaaattgt taaggctatt
      781 caagaggttg gtggagattt aagtagcata aaacctttca ctattgagat atacaacgat
      841 gaatcttttt taaaaaaaat taataatgag ttaatcattg ctaaaacaat agatttagaa
      901 ggagcattat tagcgttaaa atgggtatct gatggtcgaa atggtggtgc gtaccgagaa
      961 ttcaagctca ttatttcaga aataaagtta tcgggtgcta aatcatgata gtatctaaaa
     1021 taaaaaggaa acttagtaaa tatgattgtc gtgaatatac ccctacttac ttatctgttt
     1081 cagaaactat agaaagccgt aaagaaaggc agtactctct tattaagaaa ctgttaaagg
     1141 tgttcctaat atctgttatc attacctttc tttcatcaca ttttccttta ttaagcacta
     1201 tctacaagat aagtattgtt
//
LOCUS       DAVLZS010000121         1164 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLZS010000121 DAVLZS010000000
VERSION     DAVLZS010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.122"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(374..>1164)
                     /locus_tag="VYO88_002093"
     CDS             complement(374..>1164)
                     /locus_tag="VYO88_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000925815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEV1720102.1"
                     /translation="QIKKNFIYLIPIAIFFVYAIISGGRLPLIRLVVGALLILYIYSV
                     YGSPKSQLTKSFKMITRSLFAFLILIVLFFLLKFVLGRSSQEDFISYITRYMGGSIQL
                     FDLFVIDPIRRNKELGAETFSGIYEMLAKLGFDNNIIKGLEWRVSPNYYSLGNVYTAI
                     RRYYSDFGVIGIVICQSFTAWLYTLGYEKVRHYSLVTNVQRFRLILLAASFYPIFLNS
                     IEDVFYISMVTIGYGIQIVIFYLVFWVLLKVQVDFNKGKLTINR"
BASE COUNT          459 a          214 c          135 g          356 t
ORIGIN      
        1 agaataaaac tgtttcttat ctaaattctg gtactctaat ccaccatatt taagataaat
       61 tccatcaatc caacccagat gaaaaaaacc aatatatgtt aggtaaaaaa tatatagttg
      121 ccaataacta tactcagtta ctcccataat ttttggtaaa attagtacaa ctataaccga
      181 tgtgacaatt gtaatcagat tagacaaaaa gacatgaaat aaatttgtta taagaaactt
      241 caatttcata gctatactcc ccacctaaaa attgtttcag aagatttgta cttcccattc
      301 aaggctctct tcctccaatt caaataccta ccaaatatat ccctttatat gattcaatac
      361 attagcgcta aattcatcta tttatcgtta atttaccttt gttaaagtca acctgaactt
      421 tcagaagaac ccaaaagacc agataaaaga taacaatttg tattccatat ccaatggtaa
      481 ccattgaaat ataaaacaca tcctcgatac tatttaaaaa tattggataa aatgaagctg
      541 ctaataggat caacctaaat ctttgaacat ttgtaactaa agaataatgt ctaacttttt
      601 cataacctaa agtatataac cacgctgtaa aactctgaca aattacaata ccaattacac
      661 caaagtctga ataataacgt ctaattgcag tatacacatt tcctaaagaa taataattag
      721 gagacactct ccattctaag ccttttataa tattattgtc aaatcctaat tttgcaagca
      781 tctcataaat tcccgaaaaa gtttctgcac ctagttcttt gttacgtcgt atcggatcta
      841 taacaaataa atcaaatagt tgaattgaac ctcccatata acgagtgatg taactgataa
      901 aatcttcctg agaggagcgc cctaatacaa attttaaaag aaagaataaa actatcaaaa
      961 taagaaatgc aaacagagag cgagtaatca ttttaaaact tttggtaagt tgagatttag
     1021 gactcccgta cacagagtat atatacaata tcaacagagc tccaacaact aaccttataa
     1081 ggggcaatct accaccacta atgattgcat agacaaagaa tatagctatt ggaatcaaat
     1141 aaatgaaatt tttctttatt tgtt
//
LOCUS       DAVLZS010000122         1124 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLZS010000122 DAVLZS010000000
VERSION     DAVLZS010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.123"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..162)
                     /locus_tag="VYO88_002094"
     CDS             complement(<1..162)
                     /locus_tag="VYO88_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1720103.1"
                     /translation="MISYKPFYETLFKQGKTEYELIFHHGLSSNTLHRMKKGKPITTA
                     TLDTLCFILN"
     gene            277..>1124
                     /locus_tag="VYO88_002095"
     CDS             277..>1124
                     /locus_tag="VYO88_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720104.1"
                     /translation="MKLEDFQTFPFKSVQEYISDKEKAIKFSFLLQGDEPDRSELMKL
                     IYKDIFEWYDDKVHSGDTLITYRTAIFRKYYGKSYSKLSRDKQREILNIIKSYTEYDD
                     DFPFEFELDNKEKNVYQICNNYQIGNFGIFPKGRINPKRAQSPYNDYFDLTLSVIWDL
                     YDGTLTPDDEFKRVILDEKEYFDQFKDFETFLSDNFLTVFFDDEGYLIRLSEIDDFEE
                     YVRISNQIIYTRGLAILTYLQSMYDDNSELPTQQLEEKKTVPRPTTKELAHRTLKIAE
                     EEIDKIS"
BASE COUNT          410 a          146 c          180 g          388 t
ORIGIN      
        1 gttcaaaata aaacataggg tatctaatgt agctgtagtt attggttttc cttttttcat
       61 tctatgtagt gtattgctgg atagaccgtg gtgaaaaatt aattcgtact ctgtttttcc
      121 ttgtttaaac aaggtttcgt agaagggttt atatgaaatc atcgttctca tctcttttct
      181 aaatagataa tttcatttta tctctattaa tttgttgact atactcaata aattgactat
      241 aattagaggg agagtaattg attggaggat tttatattga aacttgaaga ttttcagact
      301 tttccattta aaagtgtcca agaatatatt tcagacaaag aaaaagcaat aaaattcagt
      361 ttcttattgc aaggagacga acctgaccgt tctgaattga tgaaattaat atataaagac
      421 attttcgaat ggtatgatga caaagtacat agtggcgaca ctcttataac atatcgtaca
      481 gcaatttttc gaaaatatta tggaaaatca tatagtaagt tatccagaga taagcaacgc
      541 gagattctta atattataaa atcatacact gaatatgatg atgattttcc tttcgaattt
      601 gagcttgaca ataaagaaaa aaacgtttat cagatttgta ataattatca aataggaaat
      661 tttggaattt ttccaaaagg aagaataaat cctaaaagag cacagtctcc ttataatgat
      721 tattttgacc ttactctatc agtaatatgg gacttatatg atggcacatt gactccagat
      781 gatgagttta aaagagtaat tttagatgaa aaggaatatt ttgaccaatt taaagatttt
      841 gaaacatttc tatccgataa cttcttaact gtattttttg atgatgaagg atatttaatt
      901 cgattatctg aaattgatga ttttgaggaa tatgtaagaa ttagtaatca aattatttat
      961 actagagggc ttgctattct aacctacctt caatcaatgt atgatgataa tagtgaattg
     1021 cctacccaac aacttgaaga aaagaaaaca gttcctagac caactaccaa agagttagca
     1081 catcgaactc ttaaaattgc agaagaagaa atagataaaa tttc
//
LOCUS       DAVLZS010000123         1070 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLZS010000123 DAVLZS010000000
VERSION     DAVLZS010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.124"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            78..227
                     /locus_tag="VYO88_002096"
     CDS             78..227
                     /locus_tag="VYO88_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1720105.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVL"
     gene            270..635
                     /locus_tag="VYO88_002097"
     CDS             270..635
                     /locus_tag="VYO88_002097"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1720106.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            632..>1070
                     /locus_tag="VYO88_002098"
     CDS             632..>1070
                     /locus_tag="VYO88_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1720107.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEY"
BASE COUNT          441 a          130 c          174 g          325 t
ORIGIN      
        1 agaaagaaaa aatcgaaaaa ttagctgaga aatactctga taacttaaac atcaaagttc
       61 aagagagagt tcgtgaaatg gcaaatgata ataagagcca ttatttgata tacagagttt
      121 taggtatttc atttgaagaa ggagaaaata tcgatttgta tcaaaataaa ggtcgttttt
      181 tatacaaata tgctggttca tttttagaag aagctgcagt actatgattt aacgaaaaat
      241 ttggtataga aaatacttaa aaagttaaca ttcctaattc tgaaagtaca aaacctaaga
      301 cttttgaaat tgattgttta gtcggagaaa aacacgcata cgaaataaaa tggtgggatg
      361 caactacaga tggagaccat ataactaaag aacacactag aataaaagtt attcataaca
      421 aaggatatat accaattcgg ttaatgttct actatccaaa tagaactcaa gccataaaaa
      481 ttcagcaaac tttagaaaca ttgtataacg gtattggagg gaaatattat tatggagatt
      541 ctgcctggga acatttaaga gcagtgaccg gtattgattt acttagtatt ctaacagata
      601 ttgcaaataa aaaaacaggg gtaaaatcaa aatgacagta ttaaaaggag ataacttaga
      661 aatattaaaa actattgaat cctcaagtat tgatttaatc tatatggacc ctcctttctt
      721 tacacagaaa acccaaaaat tatctaataa caaaaatatt atgtattcat tcgaagatac
      781 gtggacttcg attgaggatt acaaagaatt tttgtctgta agattagaag aatgcaaaag
      841 agtgctaaaa aatagtggca gtattttcgt tcattgtgat aaaattgcaa atcatcatat
      901 tagattaatt ttagataata tctttggagc agatatgttt caaagcgaaa ttatatggaa
      961 ctataaacgg tggtctaatt caaaaaaggg attattgaac aatcatcaaa acatttactt
     1021 ttattcaaag tcaaaagatt ttaaatttaa tacaattttt acagagtatt
//
LOCUS       DAVLZS010000124         1045 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLZS010000124 DAVLZS010000000
VERSION     DAVLZS010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.125"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..>1045
                     /locus_tag="VYO88_002099"
     CDS             <1..>1045
                     /locus_tag="VYO88_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1720108.1"
                     /translation="QLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAE
                     TSIVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCL
                     PEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLKYDRAVRCRVKII
                     TMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAIK
                     RYWKLIQQDSRKLSDKHFYRPTFRMHLTNKEILNKLLSYSQDLKHHYQLYQLLLFHFQ
                     NKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKL
                     IKRNAFGFRNFENF"
BASE COUNT          332 a          220 c          166 g          327 t
ORIGIN      
        1 ccaattgaag aaatatgact ttcaaaaacc ttctaaaatt ccttatcttg aaacgactgg
       61 tatgcctact agaattctcc ttagaaagcg tcgattcaag tgctatcact gttcaaaaat
      121 gatggtcgct gaaacttcta tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca
      181 aaagattgct caaaagttaa ttgaaaagat ttctatgact gatattgccc atcagctttc
      241 catctcaact tcaactgtta ttcgtaagct caatgatttt cactttaaac atgatttttc
      301 ttgtcttcct gagattatgt cttgggatga gtatgctttt acaaagggaa agatgagctt
      361 cattgcgcaa gattttaaca atctcaatat catcactgtt cttgagggaa gaacacaagc
      421 tatcattcga aatcactttc ttaaatatga tagagccgtc cgatgtcgcg tcaaaattat
      481 tactatggat atgtttagtc cttactatga cttagctaga caacttttcc catgtgctaa
      541 aatcgtgttg gatcgctttc acattgtaca acatcttagc cgtgctatga gtcgtgtgcg
      601 tgttcaaatc atgaatcaat tggatcgaaa gtctcatgaa tacaaggcta tcaagcgcta
      661 ctggaagctc atacaacagg atagtcgtaa actcagcgat aaacattttt atcgccctac
      721 ttttcgtatg catttaacca ataaagagat tttaaacaag cttttgagct attcacaaga
      781 cttgaaacat cactatcagc tctatcaact cttgctgttt cactttcaga ataaggaacc
      841 ggagaaattt ttcggactca ttgaggacaa tctaaagcag gttcatcctc tttttcagac
      901 tgtctttaaa acctttctaa aggacaaaga gaaaatcgtc aacgcccttc aactacacta
      961 ttctaacgcc aaattggaag cgaccaataa tctcatcaaa cttatcaagc gcaatgcctt
     1021 tggttttcgg aactttgaaa acttc
//
LOCUS       DAVLZS010000125         1032 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLZS010000125 DAVLZS010000000
VERSION     DAVLZS010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.126"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            215..424
                     /locus_tag="VYO88_002100"
                     /pseudo
     CDS             215..424
                     /locus_tag="VYO88_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            479..>1032
                     /locus_tag="VYO88_002101"
     CDS             479..>1032
                     /locus_tag="VYO88_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1720109.1"
                     /translation="MEGSLFECGVILQYYLGRLLFQKGNTSILCGESADEIMTFKYHS
                     VNYNQFCNDKQKSVYFSYSDYPFYVTNSIVLKKNSLLLHSFGIHPRYPYKMSEIVEMS
                     KKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTTHLFSCLNIQTLVKIILYIFRYN
                     SCMKIFNFRDKELIFFNKIVNGLI"
BASE COUNT          378 a          119 c          166 g          369 t
ORIGIN      
        1 gttatctcat gttcccgtta ccttaaataa caaaaaaata caagaattta tgagaaatgg
       61 atttatttta gattcaaata ctttagtaac cgaaattaat aaattagaat atttctctta
      121 catttctgta aataatactc ttcgtatatg tggtattgat tataatgatt caaacaattt
      181 tactaaagaa caagtattaa agaattggga ctctatgcta cgtgaatcta tattaagagt
      241 gtatagtgaa gcaggagagg ctaatattac actatcatct ggttttgatt caaattatat
      301 attatataca ttagcgaatt atacgaattc ttcaattaat gcattttgca taggaggaga
      361 aaaaggaatt aatgagattc ctgaagtaac taaaattgca aaattttatg gtataaattt
      421 attagttgat actgtaatga gccaagattt agaatatttt cccgatatag tatggagatt
      481 ggaaggaagt ctctttgaat gtggtgtcat actgcagtac tatttaggca ggttgttgtt
      541 ccaaaaaggg aacacaagta ttctttgtgg cgagtcagcg gatgaaataa tgacttttaa
      601 gtatcattct gtgaactaca atcaattttg taatgataaa cagaagtcag tatattttag
      661 ttattccgac tatccatttt atgttacaaa ttcaattgtt ttaaagaaaa atagcctact
      721 tttgcatagt tttggcattc atcctagata tccatataaa atgtctgaga ttgttgaaat
      781 gtctaaaaaa atatcagatc taaacgataa aaaagaattt cacaaaaaga actgtgagtt
      841 gaggtttcaa gatagtgttc ttgataacat aaatagtgtc ccgggtacaa ctcatttatt
      901 tagttgttta aatattcaaa cattagtaaa aattatttta tatatttttc gatacaacag
      961 ttgtatgaaa atatttaatt ttagagataa agagcttatc ttttttaata agattgtaaa
     1021 tgggctgata ca
//
LOCUS       DAVLZS010000126          899 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLZS010000126 DAVLZS010000000
VERSION     DAVLZS010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.127"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..150)
                     /locus_tag="VYO88_002102"
     CDS             complement(<1..150)
                     /locus_tag="VYO88_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV1720110.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEEL"
     gene            complement(163..>899)
                     /locus_tag="VYO88_002103"
     CDS             complement(163..>899)
                     /locus_tag="VYO88_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1720111.1"
                     /translation="KYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGYPLSQQ
                     LQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNGNFLYR
                     HIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALEFMRYK
                     VIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYESQILIIWKSV
                     EKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          306 a          173 c          108 g          312 t
ORIGIN      
        1 aagctcttca tttttagatg gaagaatgcc cttttttaaa ttatttattt ttacagaatc
       61 tatatcatat gcaacaactt tatatttaga tgcaaatagt aacgcgtagg ccagcccaac
      121 atgccccaaa ccaattactg ctatattcat aaaactactt ccttatttct taatccaaaa
      181 tctaatagaa taagctgccc cattccttaa atacaactct ttaatattgt ttaaaagttt
      241 ttcaactgat ttccagatta tcaaaatctg agattcatag cacaatattg atgatattct
      301 atcaatataa tgtttttcat caagttcctc ttgatacatt tttaattctt tagtttttcc
      361 catataacta accatactac tatcacttac atatgggaag tcctcataat atattacttt
      421 ataacgcata aattcaagcg cccttccaat actattcaca aaaacatgat caacatggtc
      481 accaagtgaa agcggacaat atacgacaca tttgtcgtct aaatgcatta acagctcttt
      541 tatgatatca ttctttaatg tgtcctcatt ttttaattca ctatagatat gacggtatag
      601 aaaattgcca tttctatctt tcctatagag acattcatag tacgataagt gtctaaaatc
      661 acactgtaga cgttcacaag ctaacctgtc ttctttcttc ctttcttcaa tcggatattt
      721 cccaaggtta cacaacttat gaaattgctt agcagagggc tgtagctgtt ggctcaaagg
      781 gtaaccagaa aatatagtaa taacaagtac aatttctcct tctgaagtta attttgaaat
      841 ataatcacca caggaaaaaa ttgcgtcatc taaatgtgga gataaaaata tatacttag
//
LOCUS       DAVLZS010000127          857 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLZS010000127 DAVLZS010000000
VERSION     DAVLZS010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.128"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..>857
                     /gene="phtB"
                     /locus_tag="VYO88_002104"
     CDS             <1..>857
                     /gene="phtB"
                     /locus_tag="VYO88_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV1720112.1"
                     /translation="LIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEERIARIIP
                     LRYRSNHWVPDSRPEQPSPQPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFE
                     ENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGTKKTDLPSSDREFYNKAYDLLA
                     RIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVEDILAFLAPIRHPERLGKPNS
                     QITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEA
                     ERAAAQAYA"
BASE COUNT          273 a          188 c          178 g          218 t
ORIGIN      
        1 gccttatttt cgacccagcg caaatcacaa gtcgaaccgc cagaggtgta gctgtccctc
       61 atggtaacca ttaccacttt atcccttatg aacaaatgtc tgaattggaa gaacgaattg
      121 ctcgtattat tccccttcgt tatcgttcaa accattgggt accagattca agaccagaac
      181 aaccaagtcc acaacctagt ccaagtccgc aacctgcacc aaatcctcaa ccagctccaa
      241 gcaatccaat tgatgagaaa ttggtcaaag aagctgttcg aaaagtaggc gatggttatg
      301 tctttgagga gaatggagtt tctcgttata tcccagccaa ggatctttca gcagaaacag
      361 cagcaggcat tgatagcaaa ctggccaagc aggaaagttt atctcataag ctaggaacta
      421 agaaaactga cctcccatct agtgatcgag aattttacaa taaggcttat gacttactag
      481 caagaattca ccaagattta cttgataata aaggtcgaca agttgatttt gaggctttgg
      541 ataacctgtt ggaacgactc aaggatgtct caagtgataa agtcaagtta gtggaagata
      601 ttcttgcctt cttagctccg attcgtcatc cagaacgttt aggaaaacca aattcgcaaa
      661 ttacctacac tgatgatgag attcaagtag ccaagttggc aggcaagtac acaacagaag
      721 acggttatat ctttgatcct cgtgatataa ccagtgatga gggggatgcc tatgtaactc
      781 cacatatgac ccatagccac tggattaaaa aagatagttt gtctgaagct gagagagcgg
      841 cagcccaggc ttatgct
//
LOCUS       DAVLZS010000128          783 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLZS010000128 DAVLZS010000000
VERSION     DAVLZS010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.129"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(<1..>783)
                     /locus_tag="VYO88_002105"
     rRNA            complement(<1..>783)
                     /locus_tag="VYO88_002105"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          164 a          250 c          164 g          205 t
ORIGIN      
        1 agggatgtca agacctggta aggttcttcg cgttgcttcg aattaaacca catgctccac
       61 cgcttgtgcg ggcccccgtc aattcctttg agtttcaacc ttgcggtcgt actccccagg
      121 cggagtgctt aatgcgttag ctacggcact aaaccccgga aagggtctaa cacctagcac
      181 tcatcgttta cagcgtggac taccagggta tctaatcctg tttgctcccc acgctttcga
      241 gcctcagcgt cagttacaag ccagagagcc gctttcgcca ccggtgttcc tccatatatc
      301 tacgcatttc accgctacac atggaattcc actctcccct cttgcactca agttaaacag
      361 tttccaaagc ctactatggt taagccacag cctttaactt cagacttatc taaccgcctg
      421 cgctcgcttt acgcccaata aatccggaca acgctcggga cctacgtatt accgcggctg
      481 ctggcacgta gttagccgtc cctttctggt aagataccgt cacagtgtga actttccact
      541 ctcacactcg ttcttctctt acaacagagc tttacgatcc gaaaaccttc ttcactcacg
      601 cggcgttgct cggtcagact tccgtccatt gccgaagatt ccctactgct gcctcccgta
      661 ggagtctggg ccgtgtctca gtcccagtgt ggccgatcac cctctcaggt cggctatgta
      721 tcgtcgcctt ggtgagccgt taccccacca actagctaat acaacgcagg tccatctggt
      781 agt
//
LOCUS       DAVLZS010000129          654 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLZS010000129 DAVLZS010000000
VERSION     DAVLZS010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..654
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.130"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            <1..622
                     /locus_tag="VYO88_002106"
     CDS             <1..622
                     /locus_tag="VYO88_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1720113.1"
                     /translation="VPYLKEGGEYQIKNLSYKFTDDECLSLKDISFKLGKIYGIIGSN
                     GRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFTDEVFNEL
                     RLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAIASVMCKNSLFVFFDEP
                     SSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADEIFEL"
BASE COUNT          252 a           76 c          124 g          202 t
ORIGIN      
        1 agttccttat ttaaaagaag gtggagagta tcagataaaa aatcttagct acaaatttac
       61 tgatgatgag tgtttaagct taaaagatat ttcgttcaag cttgggaaaa tttatggcat
      121 aataggatcc aacggacgag gaaaatcaac gcttttaaga tgtttaatag gtcttgagaa
      181 aaaatcaaaa gaagaaattt attttaaggg agagaagcta tctaaaaaag aaagactcaa
      241 aaactcttca cttgttatgc aagatgtaaa tcatcaatta ttcacagatg aagtattcaa
      301 cgagcttaga ttaggagtaa agaattttga tgaagaaaag gcgaaaatca tcttaaaaga
      361 tttaggcctg gacgaattta ttgaaaggca tccgatgagt ttatcaggag ggcaaaagca
      421 aaggcttgca atagcatctg ttatgtgcaa gaattctcta tttgtctttt ttgacgaacc
      481 ttcaagtggt atggattatt ccaatatgat aaaaatctct gaactgatta ataagtataa
      541 aaccatggat aaaataattt ttattgtttc ccatgatata gaatttttaa atgaagtggc
      601 agatgaaatt tttgaattgt aaaatagagt ctgttaaaca tgtctataga acta
//
LOCUS       DAVLZS010000130          609 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLZS010000130 DAVLZS010000000
VERSION     DAVLZS010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..609
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.131"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            59..538
                     /locus_tag="VYO88_002107"
     CDS             59..538
                     /locus_tag="VYO88_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1720114.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          237 a           76 c          137 g          159 t
ORIGIN      
        1 gaaaatggaa caaatgtgtt ttctaatctg ttagactgta tctagaaagg ggaaaattat
       61 gattaaagaa ttgtatgaag aagtccaagg gactgtgtat aagtgtagaa atgaatatta
      121 ccttcattta tgggaattgt cggattggga ccaagaaggc atgctctgct tacatgaatt
      181 gattagtaga gaagaaggac tggcagacga tattccacgt ttaaggaaat atttcaaaac
      241 caagtttcga aatcgaattt tagactatat ccgtaagcag gaaagtcaga agcgtagata
      301 cgataaagaa ccctatgaag aagtgggtga gatcagtcat cgtataagtg aggggggtct
      361 ctggctagat gattattatc tctttcatga aacactaaga gattatagaa acaaacaaag
      421 taaagagaaa caagaagaac tagaacgcgt cttaagcaat gaacgatttc gagggcgtca
      481 aagagtatta agagacttac gcattgtgtt taaggagttt actatccgta cccattagta
      541 agtcatgcaa aaaaaataaa aaaaaattag aaaaagtagt tgacaaagtt tgaaaagact
      601 gtataatag
//
LOCUS       DAVLZS010000131          604 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLZS010000131 DAVLZS010000000
VERSION     DAVLZS010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.132"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            complement(218..514)
                     /locus_tag="VYO88_002108"
     CDS             complement(218..514)
                     /locus_tag="VYO88_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV1720115.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
BASE COUNT          215 a          109 c           77 g          203 t
ORIGIN      
        1 tttttttact ttggataggc agtttcatat tataacgatt caaagtagcg taatctacta
       61 ccaaaaaaag taaaaataat ttcccttgaa aaggaagata gcttttaaaa tagattgaca
      121 aacttatgat aacaaaaaac aaaagggtta tcccaataaa attaagataa cctaaaatac
      181 tttcacattc ttttttagaa agtattttca tctagttcta ccatagagct gctttagcag
      241 cacctttctt tttcaatata taaagaactg ttgctgcaat acccgaacca atagaaccta
      301 ctcctgtgat tgcacctaca attgaaatta ctgctgtaac tgtactataa gcactaatca
      361 aattgactac agtagcagca gcttttgtcg aaattcctaa tgtcccagcc aacataggaa
      421 aagaaacaac acctaagctt aaccaactaa tgactgctaa cattgctgaa acaataagaa
      481 atttattatg aaattccatt cttttagatt tcattttagt gtactccttt tgtatattat
      541 gtatgtttta ttgagagtta attcgcacat gttgtattcc taactctctt caaatgttcg
      601 tcta
//
LOCUS       DAVLZS010000132          530 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLZS010000132 DAVLZS010000000
VERSION     DAVLZS010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.denovo.133"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            1..>530
                     /locus_tag="VYO88_002109"
     CDS             1..>530
                     /locus_tag="VYO88_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV1720116.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNL"
BASE COUNT          176 a          112 c           85 g          157 t
ORIGIN      
        1 atggaacaat tacattttat cacaaaactg ctcgatatta aagacccaaa catcaagatt
       61 ctagatatca tcaatatgga tacccacaaa gaaattatcg ctaagctgga ttatgaggct
      121 ccatcttgcc ctgattgtgg aagtctaatg aagaaatatg actttcaaaa accgtctaag
      181 atcccttacc tcgaaacaac tggtatgcct tctagaattc tccttagaaa acgccgtttc
      241 aagtgctatc actgttcaaa aatgatggtt gctgagactc ccctggtaaa gaaaaatcac
      301 caaatccctc gtatcatcaa ccaaaaaatt gctcaaaagt taattgaaaa aatttctatg
      361 actgatattg cccatcagct ggccatttca acttcaactg tcattcgcaa gctcaatgac
      421 tttcactttg agcatgattt ttctcggctt ccaaagatta tgtcttggga tgagtatgcc
      481 ttcactaagg gaaagatgag tttcattgcg caagattttg ataatcttaa
//
LOCUS       DAVLZS010000133         2139 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037323
            SAMN33607074-rid17938853.guided.107, whole genome shotgun sequence.
ACCESSION   DAVLZS010000133 DAVLZS010000000
VERSION     DAVLZS010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607074
            Sequence Read Archive: SRR23725481
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721358.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721358.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:57:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,113
            CDSs (total)                      :: 2,065
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 63 of 133
            Pseudo Genes (incomplete)         :: 57 of 133
            Pseudo Genes (internal stop)      :: 49 of 133
            Pseudo Genes (multiple problems)  :: 31 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2139
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607074-rid17938853.guided.107"
                     /strain="AUSMDU00037323"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1692"
     gene            302..730
                     /locus_tag="VYO88_002110"
     CDS             302..730
                     /locus_tag="VYO88_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1720117.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVDLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            809..1396
                     /locus_tag="VYO88_002111"
     CDS             809..1396
                     /locus_tag="VYO88_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV1720118.1"
                     /translation="MGGNPPIKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            1648..1926
                     /locus_tag="VYO88_002112"
     CDS             1648..1926
                     /locus_tag="VYO88_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEV1720119.1"
                     /translation="MEKVASLGVPMCKPISIELCDDEVHSLHEWIDGRDAIDSILTYS
                     ENQQYTYGVEAGKILRKIHTIPATEVCEDWEIFFYLKIDDKISNEMIW"
     gene            2031..>2139
                     /locus_tag="VYO88_002113"
     CDS             2031..>2139
                     /locus_tag="VYO88_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEV1720120.1"
                     /translation="MDDEASKQLSDSRFKILVGVQRTTFEEMLAVLKTAY"
BASE COUNT          790 a          295 c          435 g          619 t
ORIGIN      
        1 cacaaggaaa tcatcgccaa actggactac gacgccccat gttgaggcag tatcactgct
       61 tgtacaagct gaggcatcag cgaagtagaa gtaaatgatc tcccatacga taggactcgt
      121 agaatgagga gggaaaccga cgaaatgata aggtaagtcc gaaccgctga gtgcgtggct
      181 ctgctcttcc gatctgagac agtcgaaaag tagaagggga tggtattggt atcaatcaat
      241 gagtaacaaa gtatcagcat gattcgaaac atttacttgt aatttgcgga ggaacatcaa
      301 tatggatgga ataacaaaag attttataaa aacggctaaa ctaatgaaac aattatggcc
      361 ccaattgacc gataaagaag ctattgatga agtaaaaaaa tatacgaatg gcaaaaatac
      421 tgcaatcttt actgaagttg aaggtgacac aattgtagat ctagcactat gttcactcag
      481 atttgattat gttgaaggtt gtaaatatag tcctgttgga ttcttagaag ggattattgt
      541 tgacgaggaa tatcgtttaa aggatattgc taaaaatctc tgtacaaaat gtgaggaatg
      601 ggcgaaaaat aaaggatgta aggaatttgc aagtgactgt actttaacga atacggattc
      661 tataagattt catctcaata ttggatttca ggaggcaaat agaattattc attttaagaa
      721 aaaattataa tttagaaacg tgaataaact tgtttaaact ttatgtatct ttagaaagtg
      781 tgttaacttg aaagaacaaa tttttttgat gggtgggaat cccccaataa agaaatatag
      841 tattgttgat aaaattgtat tatcaaccaa gattaaaaga attatcattt ttacagtttt
      901 tcgagaaaat tgggaaccgt acatgaaaaa gtacacggaa gtttttcaaa gtcaatttcc
      961 taatctaaac attgattact tgctcctgga cactgagcag attgatcttg atagctatct
     1021 agatgctgac ataattatca tcggtggtgg aaatacggaa aaatatattg ctacttatgt
     1081 taatcaggag ttcaaaagtt atatcgatca tatgcttaat aaagaggcaa aaattatagg
     1141 attttctgca ggagccctac tattaggaga aaaagtctat gtctcaccta atgataattc
     1201 agatcatcag ataaagataa aaaatggatt aggactcttt agtcagtttt taattagtgt
     1261 ccattatgat tcctggaatg ataaagcaaa taaggataga gctgaagaac tcgttaatgt
     1321 tcccataatt ccactaaatg atcattcttg tcttgtattg gataaacttg gaaacatcat
     1381 agagaaaatt gactaacttt cataatgtaa aaatggatct aggaaataaa agtgtagacg
     1441 aactggatag gttactagtg aaaactgcaa aaagtgttgt aaagtgaatc ggagtgtgct
     1501 tgatggattt tagtagtaag atagccataa ataaaggctg gtcagatgga taaaaaatat
     1561 tgtgtgacag ttcaaaatca gtaaacatat ttcttgcgtg tttctgataa gtcgaagtta
     1621 gattataaaa aaattgaatt tgatacgatg gagaaagtag cttctcttgg agttccgatg
     1681 tgtaaaccaa ttagcattga actctgcgat gacgaagtac attctttaca cgaatggata
     1741 gacggaagag atgcaataga tagcatttta acttattcag aaaaccaaca atacacatat
     1801 ggtgtagaag caggaaagat acttagaaag attcatacaa ttcctgctac agaagtttgt
     1861 gaagattggg aaatcttttt ttatctaaaa attgatgata aaatctccaa cgaaatgata
     1921 tggtaagtcc gaaacgctca gtgtgtaagc ttgttgctaa aagcgtaaaa accttggaac
     1981 gaaaggaata atagacttcc tgcgaaacaa aaatacaata caataaaact atggatgatg
     2041 aagcaagtaa acaattgagc gatagccgtt tcaagatcct tgtaggtgtt cagcgcacga
     2101 cttttgaaga gatgttagct gtgttaaaaa cagcttatc
//
